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Mechanical ventilation management and airway pressure release ventilation practice in acute respiratory distress syndrome: A cross‐sectional survey of intensive care unit clinicians in mainland China 急性呼吸窘迫综合征的机械通气管理和气道压力释放通气实践:中国大陆重症监护室临床医生横断面调查
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 2024-07-03 DOI: 10.1002/hkj2.12033
Yinxia Lv, Xinyang Jin, MeiLing Dong, Lan Yang, Bo Wang, Guopeng Liang, Peng Wang, Xiaorong Jing, Yiyi Yang, Yunqing Yang, Zhen Wang, Xuelian Liao, Wei Yang, Shuo Zhu, Mandie Lu, Yang Kang, Yongfang Zhou
Airway pressure release ventilation (APRV) has become increasingly popular for the management of acute respiratory distress syndrome (ARDS); however, its clinical impact remains a topic of debate. Furthermore, there is a gap between the guidelines and the actual clinical practices in mechanical ventilation management for ARDS. This survey aimed to explore the utilization of APRV and mechanical ventilation strategies for ARDS in Chinese intensive care unit (ICU) clinicians.A comprehensive 34‐item survey was distributed online platforms amongst ICU clinicians across mainland China from June to August 2019.A total of 420 valid responses were collected, with 57.4% (241) originating from academic hospitals and 42.6% (179) from non‐academic hospitals. Of the respondents, 98.6% (414) recognized the significance of low tidal volume ventilation for ARDS prognosis, 85.2% adhered to a tidal volume below 8 mL/kg predicted body weight, and most (46.4%) selected the initial positive end‐expiratory pressure within the range of 5–10 cmH2O based on experience. Among the respondents, 62.1% (261) reported familiarity with APRV and 41.9% (176) had implemented APRV. Of those who had utilized APRV, 93.2% (164) believed in its effectiveness for ARDS patients and 69.3% (122) advocated for early application of APRV. Substantial variations were noted regarding APRV initiation settings and the preservation of spontaneous breathing during APRV. Academic hospitals exhibited higher usage rates of lung recruitment, neuromuscular blockade, prone ventilation, and acquaintance with and utilization of APRV compared to non‐academic hospitals (all p values ≤ 0.001).Our findings highlight opportunities for improvement in mechanical ventilation management for ARDS, particularly in non‐academic hospitals. Additionally, a significant proportion of clinicians demonstrated limited knowledge of APRV, and there was a lack of consensus on its application. Further training and larger‐scale clinical trials are required to validate the efficacy and utilization of APRV in managing ARDS.
气道压力释放通气(APRV)在急性呼吸窘迫综合征(ARDS)的治疗中越来越受欢迎,但其临床影响仍是一个争论的话题。此外,ARDS 机械通气管理指南与实际临床实践之间也存在差距。本调查旨在探讨中国重症监护病房(ICU)临床医生对APRV和ARDS机械通气策略的使用情况。2019年6月至8月,我们在中国大陆地区的ICU临床医生中发放了一份包含34个项目的综合调查问卷,共收集到420份有效回复,其中57.4%(241份)来自学术医院,42.6%(179份)来自非学术医院。受访者中,98.6%(414 人)认识到低潮气量通气对 ARDS 预后的意义,85.2%坚持潮气量低于 8 mL/kg 预测体重,大多数(46.4%)根据经验选择初始呼气末正压在 5-10 cmH2O 范围内。在受访者中,62.1%(261 人)表示熟悉 APRV,41.9%(176 人)曾使用过 APRV。在使用过 APRV 的受访者中,93.2%(164 人)相信 APRV 对 ARDS 患者有效,69.3%(122 人)主张尽早使用 APRV。在 APRV 启动设置和 APRV 期间保留自主呼吸方面存在巨大差异。与非学术性医院相比,学术性医院在肺募集、神经肌肉阻滞、俯卧位通气以及熟悉和使用 APRV 方面的使用率更高(所有 p 值均≤ 0.001)。此外,相当一部分临床医生对 APRV 的了解有限,对其应用缺乏共识。需要进一步的培训和更大规模的临床试验来验证 APRV 在管理 ARDS 中的有效性和应用。
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引用次数: 0
Comparison of film array pneumonia panel to routine diagnostic methods and its potential impact in an adult intensive care unit in Hong Kong and the potential role of emergency departments 薄膜阵列肺炎面板与常规诊断方法的比较及其对香港成人重症监护病房的潜在影响和急诊科的潜在作用
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2024-06-14 DOI: 10.1002/hkj2.12018
Ping Wu, Kin Ho Steven Ling
Pneumonia is a leading diagnosis for patients requiring critical care. Prediction of the causal organisms has proved challenging, and antibiotic overuse is a burning issue.This study aimed to compare the results of the BioFire FilmArray Pneumonia Panel (PN Panel) to standard diagnostic methods and evaluate its potential impact in an intensive care unit (ICU).This is a retrospective study including adult patients admitted to the ICUs with a diagnosis of pneumonia. The agreement between the PN panel results and the standard diagnostic method was analyzed. Actual and potential adjustments of antimicrobials after the PN panel results were reviewed and compared.Two hundred ninety three patients with pneumonia were included. The PN panel identified at least one pathogen in 159 specimens (54.2%), while the standard diagnostic method identified at least one pathogen in 132 specimens (45.0%). Positive percentage agreement between the PN panel and standard‐of‐care culture reached 94%, and negative percentage agreement reached 97%. Among 293 patients, the availability of PN results led to escalation of antimicrobials in 38 (19%) patients and de‐escalation or discontinuation of antimicrobials in 95 (32.4%) patients.This pilot study showed the PN panel could provide accurate results on the causative pathogens and detect resistant bacteria. It could reduce the use of broad‐spectrum antibiotics and overall antibiotic use. If the PN panel could be checked at the emergency department, targeted antibiotics could be administered when the patient arrived at the ICU.
肺炎是危重症患者的主要诊断病症。本研究旨在比较 BioFire FilmArray 肺炎面板(PN 面板)与标准诊断方法的结果,并评估其在重症监护病房(ICU)中的潜在影响。这是一项回顾性研究,包括重症监护病房收治的诊断为肺炎的成年患者。研究分析了 PN 小组的结果与标准诊断方法之间的一致性。研究还回顾并比较了根据 PN 面板结果对抗菌药物进行的实际和潜在调整。PN 小组在 159 份标本(54.2%)中至少确定了一种病原体,而标准诊断方法在 132 份标本(45.0%)中至少确定了一种病原体。PN 小组与标准培养方法之间的正比例一致率达到 94%,负比例一致率达到 97%。在 293 名患者中,有 38 名患者(19%)因获得 PN 结果而升级了抗菌药物,95 名患者(32.4%)因获得 PN 结果而降级或停用了抗菌药物。这项试点研究表明,PN 面板可提供致病病原体的准确结果,并能检测出耐药菌,从而减少广谱抗生素的使用和抗生素的总体使用量。如果能在急诊科检查 PN 面板,就能在患者到达重症监护室时使用有针对性的抗生素。
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引用次数: 0
Questionnaire survey on point‐of‐care ultrasound utilization during cardiac arrest among emergency physicians in Hong Kong 关于香港急诊医生在心脏骤停期间使用护理点超声波的问卷调查
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2024-05-23 DOI: 10.1002/hkj2.12024
Kwong Tat Lo, Chun Hei Kwok, Kenneth Kin Wing Suen
Although point‐of‐care ultrasound (POCUS) is recognized as a useful diagnostic and prognostic tool during the management of out‐of‐hospital cardiac arrest (OHCA), opposing viewpoints exist. The objectives of this study are to investigate the knowledge, attitude, and practice (KAP) in POCUS utilization during OHCA among emergency medicine (EM) physicians in Hong Kong and to identify their barriers.A cross‐sectional questionnaire was conducted among EM physicians in 9 accident and emergency departments in Hong Kong. The questionnaire assessed participants' demographics, knowledge, attitude, practices, and barriers on this issue. Composite scores for KAP were calculated. Subgroup analysis and multiple regression analysis were used to explore the correlation between KAP and participants' demographics. Participants' barriers were evaluated by binary and open‐ended questions.A total of 224 questionnaires were distributed and 150 questionnaires were returned (response rate: 67.0%). Statistically significant associations of knowledge and attitude with practice were demonstrated (both p < 0.001). Independent predictors of more frequent POCUS use in OHCA included EM fellowship status (p = 0.005), receiving training on this issue (p < 0.001), and working in large hospitals (p = 0.007). The top‐ranked barriers were chaotic environment (74%), no structural education on this practice (63%), and the lack of staff (61%).The knowledge and attitude of performing POCUS during OHCA were demonstrated to enhance EM physicians' practice. By improving physicians' knowledge and removing the possible barriers they are facing, POCUS can be optimally utilized during OHCA to improve patient care.
尽管在院外心脏骤停(OHCA)的救治过程中,床旁超声(POCUS)被认为是一种有用的诊断和预后工具,但仍存在相反的观点。本研究旨在调查香港急诊科医生在院外心脏骤停期间使用 POCUS 的知识、态度和实践(KAP),并找出其障碍。调查问卷对参与者的人口统计学、知识、态度、实践和障碍进行了评估。并计算出 KAP 的综合得分。采用分组分析和多元回归分析来探讨 KAP 与参与者人口统计学特征之间的相关性。共发放了 224 份问卷,收回 150 份(回复率:67.0%)。调查结果显示,知识和态度与实践之间存在明显的统计学关联(P 均小于 0.001)。在 OHCA 中更频繁使用 POCUS 的独立预测因素包括急诊科研究员身份(p = 0.005)、接受过相关培训(p < 0.001)和在大型医院工作(p = 0.007)。排名靠前的障碍是混乱的环境(74%)、没有关于这一实践的结构性教育(63%)和缺乏工作人员(61%)。通过提高医生的知识水平并消除他们可能面临的障碍,POCUS 可在 OHCA 期间得到最佳利用,从而改善对患者的护理。
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引用次数: 0
Burnout in emergency physicians in Hong Kong—A cross‐sectional study on its prevalence, associated factors, and impact 香港急诊医生的职业倦怠--关于其发生率、相关因素和影响的横断面研究
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2024-05-17 DOI: 10.1002/hkj2.12025
Tsz Kit Chan, C. Lui, Wing Yee Clara Wu, Timothy Rainer, Chin San Leung
To evaluate the prevalence of burnout, its underlying personal or occupational stressors, and impact on individual well‐being and patient care.Cross‐sectional survey.All emergency physicians in the public and the private sector in Hong Kong.Self‐administered, anonymous, voluntary questionnaires were distributed in physical and electronic forms from April to June 2022. Burnout was assessed by the Maslach Burnout Inventory (MBI). Stressors were assessed by questions on demographic, occupational, and social background. Impact was assessed by the Patient Health Questionnaire‐9 (PHQ‐9) for depression and questions on job satisfaction and self‐perceived patient care.The response rate was 37.8% (n = 241). Prevalence of high overall burnout was 28.2% (n = 68), with 47.7% (n = 115) having high emotional exhaustion, 63.1% (n = 152) high depersonalization, and 56% (n = 135) low personal accomplishment. A higher burnout rate was observed in younger age, female, not married, job position (associate consultant, resident specialist, and higher trainee), working on shift duty, more night shifts, and consecutive shifts. Burnout is also associated with depression, suicidal idea, consideration of quitting, less job satisfaction, and less favorable patient care (p < 0.05).Burnout is prevalent in emergency physicians in Hong Kong, and its impact on individual well‐being and clinical care was evident. A higher burnout rate was observed in younger doctors and also fellows. Identified stressors such as shift pattern should be addressed and potentially improved. Further strategies should be explored to reduce burnout in our colleagues.
在2022年4月至6月期间,以实物和电子形式发放匿名自愿自填问卷。倦怠感通过马斯拉赫倦怠感量表(Maslach Burnout Inventory,MBI)进行评估。压力源通过人口、职业和社会背景问题进行评估。患者健康问卷-9(Patient Health Questionnaire-9,PHQ-9)针对抑郁症以及工作满意度和自我感觉患者护理方面的问题对影响进行了评估。总体倦怠感较高的比例为 28.2%(n = 68),其中 47.7%(n = 115)有较高的情感衰竭,63.1%(n = 152)有较高的人格解体,56%(n = 135)有较低的个人成就感。据观察,年龄较小、女性、未婚、工作职位(副顾问、常驻专家和高级实习生)、轮班工作、夜班较多和连续轮班的倦怠率较高。职业倦怠还与抑郁、自杀念头、考虑辞职、工作满意度较低和病人护理较差有关(P < 0.05)。职业倦怠在香港急诊医生中普遍存在,对个人福祉和临床护理的影响显而易见。年轻医生和研究员的职业倦怠率较高。已发现的压力因素(如轮班模式)应得到解决和改善。我们还应该探索更多的策略,以减少同事的职业倦怠。
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引用次数: 0
Factors for predicting 28‐day mortality in older patients with suspected of having sepsis in the emergency department 预测急诊科疑似败血症老年患者 28 天死亡率的因素
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2024-05-12 DOI: 10.1002/hkj2.12023
Pitsucha Sanguanwit, C. Yuksen, J. Khorana, Yuranun Phootothum, Siriporn Damdin, Krongkarn Sutham
Older patients face increased sepsis risk, requiring precise prognostic tools in the emergency department (ED). This study aimed to explore factors predicting 28‐day mortality among older (≥60 years) patients with suspicion of sepsis in the ED.We performed a retrospective cohort study. Data for all older patients with clinical suspected sepsis presenting to the ED from 1 October 2018 to 31 December 2018, were collected. Prognostic factors, characteristics, comorbidities, vital signs at triage, the emergency severity score, initial laboratory results, and sepsis bundle treatment were analyzed using univariable and multivariable Cox regression. Hazard ratios (HR) were calculated using these analytical methodologies to prognosticate 28‐day mortality.A total of 329 older patients with suspected sepsis were included. The overall 28‐day mortality was 10.33%. Independent prognostic factors that were significantly associated with 28‐day mortality were malignancy (adjusted hazard ratio [aHR]: 3.67; 95% confidence interval [CI]: 1.90, 7.09; p < 0.01), oxygen saturation ≤93% (aHR: 3.37; 95% CI: 1.79, 3.43; p < 0.01), and dependent status (hazard ratio [HR]: 2.27; 95% CI: 1.14, 4.53; p = 0.02).This study suggests that “MOD”; M‐Malignancy, O‐Oxygen saturation ≤93%, and D‐Dependent status are significant prognostic indicators for 28‐day mortality among older patients with suspected sepsis in the ED.The trial was retrospectively registered in the Thai Clinical Trial Registry on 06/05/2022, identification number TCTR20220506006.
老年患者面临的败血症风险增加,急诊科(ED)需要精确的预后工具。本研究旨在探讨预测急诊科疑似败血症老年患者(≥60 岁)28 天死亡率的因素。研究收集了2018年10月1日至2018年12月31日期间所有到急诊科就诊的临床疑似败血症老年患者的数据。使用单变量和多变量 Cox 回归分析了预后因素、特征、合并症、分诊时的生命体征、急诊严重程度评分、初始实验室结果和脓毒症捆绑治疗。共纳入了 329 名老年疑似败血症患者。28天的总死亡率为10.33%。与 28 天死亡率显著相关的独立预后因素是恶性肿瘤(调整后危险比 [aHR]:3.67;95% 置信区间 [CI]:1.90, 7.09; p < 0.01)、血氧饱和度 ≤93% (aHR: 3.37; 95% CI: 1.79, 3.43; p < 0.01) 和依赖状态(危险比 [HR]: 2.27; 95% CI: 1.14, 4.53; p = 0.02)。该研究表明,"MOD"、M-恶性肿瘤、O-氧饱和度≤93%和D-依赖状态是影响急诊室疑似败血症老年患者28天死亡率的重要预后指标。该试验于2022年5月6日在泰国临床试验登记处进行了回顾性登记,登记号为TCTR20220506006。
{"title":"Factors for predicting 28‐day mortality in older patients with suspected of having sepsis in the emergency department","authors":"Pitsucha Sanguanwit, C. Yuksen, J. Khorana, Yuranun Phootothum, Siriporn Damdin, Krongkarn Sutham","doi":"10.1002/hkj2.12023","DOIUrl":"https://doi.org/10.1002/hkj2.12023","url":null,"abstract":"Older patients face increased sepsis risk, requiring precise prognostic tools in the emergency department (ED). This study aimed to explore factors predicting 28‐day mortality among older (≥60 years) patients with suspicion of sepsis in the ED.We performed a retrospective cohort study. Data for all older patients with clinical suspected sepsis presenting to the ED from 1 October 2018 to 31 December 2018, were collected. Prognostic factors, characteristics, comorbidities, vital signs at triage, the emergency severity score, initial laboratory results, and sepsis bundle treatment were analyzed using univariable and multivariable Cox regression. Hazard ratios (HR) were calculated using these analytical methodologies to prognosticate 28‐day mortality.A total of 329 older patients with suspected sepsis were included. The overall 28‐day mortality was 10.33%. Independent prognostic factors that were significantly associated with 28‐day mortality were malignancy (adjusted hazard ratio [aHR]: 3.67; 95% confidence interval [CI]: 1.90, 7.09; p < 0.01), oxygen saturation ≤93% (aHR: 3.37; 95% CI: 1.79, 3.43; p < 0.01), and dependent status (hazard ratio [HR]: 2.27; 95% CI: 1.14, 4.53; p = 0.02).This study suggests that “MOD”; M‐Malignancy, O‐Oxygen saturation ≤93%, and D‐Dependent status are significant prognostic indicators for 28‐day mortality among older patients with suspected sepsis in the ED.The trial was retrospectively registered in the Thai Clinical Trial Registry on 06/05/2022, identification number TCTR20220506006.","PeriodicalId":50401,"journal":{"name":"Hong Kong Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of COVID‐19 pandemic on pediatric traumatic injury and demographic presentations to a university emergency department COVID-19大流行对大学急诊科儿科外伤和人口病例的影响
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2024-04-19 DOI: 10.1002/hkj2.12021
Mehmet Arikan, Cem Oktay
The objective of this study is to investigate how lifestyle changes affect the emergency department (ED) presentations of pediatric patients with acute traumatic injuries during the COVID‐19 pandemic.This retrospective cohort study was conducted in the ED of Akdeniz University Hospital. We analyzed the medical records of pediatric patients who presented to our ED with acute traumatic injury during the 52‐week period after March 16, 2020, which marks the official date when in‐person education was suspended in Turkey due to COVID‐19. These records were compared with those from the 52‐week period prior to March 16, 2020 (pre‐COVID). Patients with nontraumatic presentations or follow‐up visits (e.g., dressing, suture removal, injection, etc.) were excluded from the study. The data was obtained through the Hospital Information System.The total number of ED pediatric trauma visits declined by 46%. The overall presentation rates of patients between the ages of 1 and 4 years, home injuries, falls, burns, hospitalizations, and costs per patient increased during COVID‐19. In contrast, the rate of motor vehicle accidents, sports injuries, and injuries that occurred at schools and playgrounds decreased.It should be expected that the decrease in the number of acute trauma presentations due to the implementation of distance education and lockdown restrictions will increase after the pandemic. As a result, it is necessary to pay attention to the safety of children in streets, playgrounds, and schools as the pandemic ends, as much as it will continue to be important to create safe environments for children at home. In order to reduce mortality and morbidity due to pediatric traumatic injuries, all authorized people, including the relevant ministries, should take precautions to protect children from injuries, and pediatric trauma should be addressed as a preventable public health problem.
本研究旨在调查生活方式的改变如何影响 COVID-19 大流行期间急诊科(ED)收治的急性外伤儿科患者。我们分析了在 2020 年 3 月 16 日(即 COVID-19 在土耳其正式暂停现场教育的日期)之后的 52 周内因急性外伤而到急诊室就诊的儿科患者的医疗记录。我们将这些记录与 2020 年 3 月 16 日之前 52 周(COVID 前)的记录进行了比较。非创伤性就诊或复诊(如包扎、拆线、注射等)的患者不在研究范围内。研究数据通过医院信息系统获取。在 COVID-19 期间,1-4 岁患者的总体就诊率、家庭伤害、跌倒、烧伤、住院率和每位患者的费用均有所上升。与此相反,机动车事故、运动伤害以及在学校和游乐场所发生的伤害的发病率却有所下降。可以预见的是,由于实施远程教育和封锁限制而导致的急性创伤就诊人数的减少在大流行后将会增加。因此,随着大流行的结束,有必要关注儿童在街道、游乐场和学校的安全,就像为儿童创造安全的家庭环境一样重要。为了降低小儿外伤导致的死亡率和发病率,包括相关部门在内的所有相关人员都应采取预防措施,保护儿童免受伤害,并将小儿外伤作为可预防的公共卫生问题加以解决。
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引用次数: 0
Comparative etiological analysis of critical patients presenting to the emergency department with altered consciousness across age groups: A prospective observational study 不同年龄段急诊科意识改变危重病人的病因比较分析:前瞻性观察研究
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2024-04-18 DOI: 10.1002/hkj2.12022
Harun Yildirim, E. Armağan, Ataman Kose, S. Eraybar, E. Ahun, Pinar Cinar Sert
The aim of our study is to assess the relationship between altered consciousness in patients presenting to the emergency department (ED) without a history of trauma and the physiological changes associated with aging. Additionally, we aim to compare diagnostic differences between patients under the age of 65 and those aged 65 and above.This prospective study was conducted at the ED of Uludağ University Medical Faculty Hospital over a 1‐year period from December 2012 to November 2013. Patients aged 18 and above presenting with non‐traumatic altered consciousness were included, and they were categorized into two groups based on age: <65 years and ≥65 years. Comparison between age groups included gender, seasonal presentation, vital signs, consciousness level, Glasgow Coma Scale (GCS) score, requested consultations, diagnoses, and outcomes.Out of 646 patients, 312 (48%) were female, and 334 (52%) were male, with a mean age of 64.9 ± 16.4 years. The highest number of admissions for altered consciousness occurred during the summer season (n = 200, 31%). In the 65 and above age group, a statistically significant elevation was found in the mean systolic blood pressure (p < 0.05). In neurological diagnoses, cerebrovascular events were observed most frequently, while in non‐neurological diagnoses, endocrine/metabolic diseases were more common. It was observed that GCS scores were lower in neurological diagnoses (p = 0.020). Discharges were more frequent in the under 65 age group, with a statistically significant difference (p < 0.05). It was found that the mortality rate was higher in non‐neurological diagnoses, and this was statistically significant (p < 0.001).When determining the cause of altered consciousness in patients with such symptoms, a comprehensive understanding of physiological changes in elderly individuals is crucial. While high blood pressure may indicate neurological diagnoses, tachycardia, tachypnea, and fever may suggest non‐neurological causes.
我们的研究旨在评估急诊科(ED)无外伤史患者的意识改变与衰老相关生理变化之间的关系。这项前瞻性研究于 2012 年 12 月至 2013 年 11 月在乌鲁达大学医学院附属医院急诊科进行,为期 1 年。这项前瞻性研究于 2012 年 12 月至 2013 年 11 月在乌鲁达大学医学院附属医院急诊室进行,为期 1 年。研究纳入了 18 岁及以上出现非外伤性意识改变的患者,并根据年龄将他们分为两组:年龄<65岁和≥65岁。年龄组之间的比较包括性别、季节性表现、生命体征、意识水平、格拉斯哥昏迷量表(GCS)评分、就诊请求、诊断和结果。夏季因意识改变入院的人数最多(200人,31%)。在 65 岁及以上年龄组中,平均收缩压的升高具有统计学意义(P < 0.05)。在神经系统诊断中,脑血管事件最为常见,而在非神经系统诊断中,内分泌/代谢疾病更为常见。据观察,神经系统诊断的 GCS 评分较低(p = 0.020)。65 岁以下年龄组的出院率更高,差异有统计学意义(p < 0.05)。研究发现,非神经系统诊断的死亡率较高,且具有统计学意义(p < 0.001)。在确定出现此类症状的患者意识改变的原因时,全面了解老年人的生理变化至关重要。高血压可能提示神经系统诊断,而心动过速、呼吸过速和发热则可能提示非神经系统原因。
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引用次数: 0
April 2024 global research highlights 2024 年 4 月全球研究要点
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2024-04-06 DOI: 10.1002/hkj2.12019
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引用次数: 0
Characteristics and outcome of patients with malaria presented to a Hong Kong emergency department—A retrospective cohort analysis 香港急诊科疟疾患者的特征和预后--回顾性队列分析
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2024-03-28 DOI: 10.1002/hkj2.12015
Chi Yeung Yeung, Marc L. C. Yang, Yan W. Y. Kwong, T. Rainer
Malaria remains a significant cause of illness for return travellers in Hong Kong. However, the lack of experience of local healthcare providers in tropical medicine and non‐specific presenting symptoms may lead to underdiagnosis or delayed diagnosis of the disease. We evaluate patients presenting with malaria to a local emergency department to understand the disease presentation and outcome.A retrospective review of all patients diagnosed with malaria presenting to the emergency department from January 2009 to December 2019 was conducted. Information about patient demographics, travel history, presenting vital signs and blood results, how the diagnosis is made, clinical features and outcomes were analysed. Subgroup analysis was also performed for comparison.Among the 70 patients diagnosed with malaria, most of them were imported cases (98.6%). Most were infected with Plasmodium Falciparum (50%) and Plasmodium vivax (45.7%). The common presenting symptoms included fever (100%), nausea or vomiting (42.9%) and headache (38.6%). 43 out of 70 cases had a diagnosis made in the emergency department, either by malarial blood smear (34.3%) or incidental haematological findings (27.1%). Most cases could be discharged uneventfully (90%), with six cases requiring Intensive Care Unit admission during the stay (8.6%). Patients with diagnoses not made in AED had a significantly lower mean arterial pressure (p = 0.009) and haemoglobin level (p = 0.004). Significantly lower platelet count (p = 0.002) and higher bilirubin level (p = 0.041) were found in patients who required ICU admission. For those who had AED reattendance before diagnosis was made, their creatinine levels were significantly higher (p = 0.022) and had a longer length of stay (p = 0.021).The clinical presentation of imported malaria cases is non‐specific, and high suspicion of malaria should be raised when diagnosing febrile patients with a travel history. The history of taking malarial chemoprophylaxis is essential and should have been included in most cases. Malarial‐specific treatments were rarely given in the emergency department despite diagnosis.
疟疾仍然是导致返港旅客患病的一个重要原因。然而,由于本地医护人员缺乏热带医学方面的经验,加之患者的症状不具特异性,可能导致疾病诊断不足或延误。我们对在本地急诊科就诊的疟疾患者进行了评估,以了解疾病的表现和结果。研究分析了患者的人口统计学特征、旅行史、出现的生命体征和血液结果、诊断方式、临床特征和结果等信息。在确诊的 70 名疟疾患者中,大部分是输入性病例(98.6%)。大多数患者感染了恶性疟原虫(50%)和间日疟原虫(45.7%)。常见症状包括发烧(100%)、恶心或呕吐(42.9%)和头痛(38.6%)。在 70 个病例中,有 43 个在急诊科通过疟原虫血涂片(34.3%)或偶然的血液学检查结果(27.1%)确诊。大多数病例都能顺利出院(90%),只有 6 例病例在住院期间需要入住重症监护室(8.6%)。未经 AED 诊断的患者平均动脉压(p = 0.009)和血红蛋白水平(p = 0.004)明显较低。需要入住重症监护室的患者血小板计数明显降低(p = 0.002),胆红素水平明显升高(p = 0.041)。在确诊前接受 AED 再治疗的患者,其肌酐水平明显更高(p = 0.022),住院时间更长(p = 0.021)。服用疟原虫预防药物的病史至关重要,大多数病例都应包括在内。尽管已经确诊,但急诊科很少给予疟疾特异性治疗。
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引用次数: 0
Comparing accuracy of clinical prediction rules to predict pneumonia in children and adolescents with acute febrile respiratory illness 比较临床预测规则预测儿童和青少年急性发热呼吸道疾病肺炎的准确性
IF 0.6 4区 医学 Q3 Medicine Pub Date : 2024-03-22 DOI: 10.1002/hkj2.12010
Yuet Hong Wu, Jeremy Ho Hei Chiu, C. F. Tse, Yuet Yan Fiona Chan, K. M. Poon, C. Lui
It is a common challenge for emergency physicians to differentiate pneumonia from simple upper respiratory tract infections. Several clinical prediction rules exist to assist the diagnosis process and guide the clinical decisions of ordering investigations such as chest X‐ray (CXR).This study aims to validate and compare the accuracy of various prediction rules in the setting of children and adolescents presenting with acute febrile respiratory illness (AFRI).This was a prospective multicentre study. Three hundred and fifty‐five patients, aged 6–18 years, were recruited. Patients with immunocompromised state or hypoxia were excluded. Pneumonia was defined as diagnosis by CXR or subsequent diagnosis of pneumonia upon re‐attendance within 7 days. Clinical rules including Diehr rule, Heckerling rule, Bilkis simpler rule, the AFRI rule, the paediatric acute febrile respiratory illness rule (PAFRI) were compared in terms of accuracy of predicting pneumonia in the recruited subjects and presented as receiver operating characteristic curves.Five patients were excluded. In the 350 patients included, 38 were diagnosed as pneumonia by CXR and 1 was subsequently diagnosed as pneumonia upon re‐attendance. The area under the receiver operating characteristic curve of Diehr rule, Heckerling rule, Bilkis simpler rule, AFRI rule and PAFRI rule were 0.703, 0.565, 0.59, 0.807 and 0.846 respectively. The PAFRI rule is superior to other prediction rules in terms of diagnostic accuracy. At the cut‐off of PAFRI ≥0, the rule has high sensitivity of 97.44% and negative predictive value of 99.09%.Among the rules compared, the PAFRI rule has the highest diagnostic accuracy in assisting emergency physicians to identify pneumonia among children and adolescents aged 6–18 years presenting with AFRI.
如何区分肺炎和单纯上呼吸道感染是急诊医生面临的共同挑战。本研究旨在验证和比较各种预测规则在儿童和青少年急性发热性呼吸道疾病(AFRI)中的准确性。研究招募了 355 名 6-18 岁的患者。免疫力低下或缺氧的患者被排除在外。肺炎的定义是通过气管造影确诊或在 7 天内再次就诊时被诊断为肺炎。临床规则包括 Diehr 规则、Heckerling 规则、Bilkis 简易规则、AFRI 规则、儿科急性发热呼吸道疾病规则 (PAFRI)。在纳入的 350 名患者中,38 人经 CXR 诊断为肺炎,1 人随后在再次就诊时被诊断为肺炎。Diehr规则、Heckerling规则、Bilkis简化规则、AFRI规则和PAFRI规则的接收者操作特征曲线下面积分别为0.703、0.565、0.59、0.807和0.846。就诊断准确性而言,PAFRI 规则优于其他预测规则。在所比较的规则中,PAFRI 规则在协助急诊医生识别 6-18 岁儿童和青少年 AFRI 患者的肺炎方面具有最高的诊断准确性。
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Hong Kong Journal of Emergency Medicine
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