Pub Date : 2024-06-01DOI: 10.1016/j.jcyt.2024.03.424
E. K. Ghahe, N. Wellhausen, R. Geczy, A. Balgi, S. Clarke, C. June, S. Gill, F. Herbst-Nowrouzi
{"title":"LIPID NANOPARTICLES ENABLE EFFICIENT BASE EDITING OF CD45-DIRECTED CAR T CELLS FOR UNIVERSAL BLOOD CANCER IMMUNOTHERAPY","authors":"E. K. Ghahe, N. Wellhausen, R. Geczy, A. Balgi, S. Clarke, C. June, S. Gill, F. Herbst-Nowrouzi","doi":"10.1016/j.jcyt.2024.03.424","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.424","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141232381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.jcyt.2024.03.384
E. Ruffo, G. Falcone, V. So, M. Kvorjak, A. Deiters, J. Lohmueller
{"title":"COVALENT PROGRAMMING OF SNAP-CAR T CELLS VIA ANTIBODY ADAPTORS","authors":"E. Ruffo, G. Falcone, V. So, M. Kvorjak, A. Deiters, J. Lohmueller","doi":"10.1016/j.jcyt.2024.03.384","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.384","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141233826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.jcyt.2024.03.137
M. Goonetilleke, J. Correia, Y. Chen, H. McDonald, S.T. Chan, I. Simpson, I.M. Inocencio, W. Sievert, R. Lim
{"title":"EXTRACELLULAR VESICLES AS A THERAPY FOR THE TREATMENT OF METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS (MASH) AND HEPATOCELLULAR CARCINOMA (HCC)","authors":"M. Goonetilleke, J. Correia, Y. Chen, H. McDonald, S.T. Chan, I. Simpson, I.M. Inocencio, W. Sievert, R. Lim","doi":"10.1016/j.jcyt.2024.03.137","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.137","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141233903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.jcyt.2024.03.428
S. Mangrati, É. Schulze, U. Jung, S. Boi, S. Mathias, Y. Huang, Q.A. Rafiq
{"title":"PAAVING THE WAY TO HIGH TITRES: EVALUATING PLASMID RATIOS FOR AAV PRODUCTION UTILISING THE AMBR® 15 STIRRED-TANK BIOREACTOR","authors":"S. Mangrati, É. Schulze, U. Jung, S. Boi, S. Mathias, Y. Huang, Q.A. Rafiq","doi":"10.1016/j.jcyt.2024.03.428","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.428","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141230462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.jcyt.2024.03.154
S. Hyun, J. Lee, D. Woo, Y. Cho, K. Moon
{"title":"CARDIAC RISK ASSESSMENT OF MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES BY TELEMETRY IN CYNOMOLGUS MONKEYS","authors":"S. Hyun, J. Lee, D. Woo, Y. Cho, K. Moon","doi":"10.1016/j.jcyt.2024.03.154","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.154","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141229014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.jcyt.2024.03.446
J. Stoodley, D. S. Miraz, N. G. Riera, R. Chalcroft, R. Ellerington, C. Webster, M.J. Wood, M.A. Varela
{"title":"DIFFERENTIAL TFR1 EXPRESSION PATTERNS IMPACT TFR1 TARGETING DELIVERY STRATEGIES IN NEUROMUSCULAR DISEASE MODELS.","authors":"J. Stoodley, D. S. Miraz, N. G. Riera, R. Chalcroft, R. Ellerington, C. Webster, M.J. Wood, M.A. Varela","doi":"10.1016/j.jcyt.2024.03.446","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.446","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141229965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.jcyt.2024.03.422
M. Jain, J. Lesnik, N. Syed
{"title":"DEVELOPMENT OF A NEXT-GENERATION EX VIVO DELIVERY PLATFORM USING SILICON NANONEEDLES FOR PHYSICAL CARGO DELIVERY INTO DIFFICULT-TO-TRANSFECT CELLS","authors":"M. Jain, J. Lesnik, N. Syed","doi":"10.1016/j.jcyt.2024.03.422","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.422","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141229078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.jcyt.2024.03.194
D. Vozniuk, R. Pattarkine, E. Ntrivalas, O. Secka, M. Dontsova, A. Vladimirov, E. Feuer, C. Yang, D. Kehn, A. Johnson, F. Wafa, J. Levin, J. Zhu, J. Veliaj, B. Sa, M. Thomsen, D. Elterman, A. Kolovrat, P.D. Borge, M. Roshal, E. Maryamchik
{"title":"UNIVERSAL POST-THAW VIABILITY TESTING OF ALLOGENEIC HEMATOPOIETIC STEM CELL (HPC) COLLECTIONS SHOWS INCREASED RISK OF NON-ENGRAFTMENT AND DELAYED PLATELET ENGRAFTMENT IN PRODUCTS WITH DECREASED POST-THAW VIABLE CD34 (vCD34) YIELD.","authors":"D. Vozniuk, R. Pattarkine, E. Ntrivalas, O. Secka, M. Dontsova, A. Vladimirov, E. Feuer, C. Yang, D. Kehn, A. Johnson, F. Wafa, J. Levin, J. Zhu, J. Veliaj, B. Sa, M. Thomsen, D. Elterman, A. Kolovrat, P.D. Borge, M. Roshal, E. Maryamchik","doi":"10.1016/j.jcyt.2024.03.194","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.194","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141230031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.jcyt.2024.03.418
J. Frankish
{"title":"NOVEL NON-VIRAL DELIVERY TECHNOLOGY, SOLUPORE®, ENABLES GENE DELIVERY FOR A HEALTHIER, MORE POTENT, AND SIGNIFICANTLY MORE EFFECTIVE CAR-T THERAPY IN VIVO.","authors":"J. Frankish","doi":"10.1016/j.jcyt.2024.03.418","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.418","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141230056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.jcyt.2024.03.350
S.R. Kuenzel, M. Arriens, W. Rackwitz, J. Pappermann, J. Thiel, R. Kronstein-Wiedemann, J. Eitler, T. Tonn
{"title":"FAPα-TARGETED IMMUNOTHERAPY WITH SIBROTUZUMAB AND HIGH AFFINITY FC-RECEPTOR EXPRESSING NK92 CELLS: A PROMISING APPROACH TO REVERSE FIBROSIS","authors":"S.R. Kuenzel, M. Arriens, W. Rackwitz, J. Pappermann, J. Thiel, R. Kronstein-Wiedemann, J. Eitler, T. Tonn","doi":"10.1016/j.jcyt.2024.03.350","DOIUrl":"https://doi.org/10.1016/j.jcyt.2024.03.350","url":null,"abstract":"","PeriodicalId":505215,"journal":{"name":"Cytotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141230093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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