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Development of a methodology for radon pollution studies based on algorithms taking into account the influence of constant mountain-valley winds 根据考虑到山谷常风影响的算法,制定氡污染研究方法
Pub Date : 2024-03-13 DOI: 10.59429/ace.v7i2.1865
Andrey A.Sokolov, Vladimir A.Fomenko, Maria A.Aksenova, Nikita V.Martyushev, Boris V.Malozyemov, Manshuk F.Kerimzhanova
The article describes the development of a methodology for radon pollution studies based on algorithms that take into account the influence of constant mountain-valley winds. The solved problem of the study of radon emanations arising from the stress-strain state of rocks is an important step in the study of man-made bulk arrays on the environment and the assessment of radiation safety. Decommissioned tailings dumps eventually dry up and turn into hardening man-made bulk arrays, which negatively affect the surrounding ecosystems. The proposed methodology is implemented on the basis of the proposed algorithms for determining the optimal choice of measurement conditions, taking into account the influence of constant mountain-valley winds. As an approbation of the methodology, field studies were carried out, including measurements of the equivalent equilibrium volume activity of radon-222 at various points of the tailings dump. For this purpose, specialized methods and devices were used, which made it possible to determine the concentration of radon in the air and evaluate its emanations from the tailings dump. The data obtained were processed and analyzed using specialized software and algorithmic software, which allows for a detailed analysis and evaluation of the values.
文章介绍了氡污染研究方法的发展情况,该方法基于考虑到山谷常风影响的算法。研究岩石应力应变状态引起的氡散发问题的解决,是研究人造散堆对环境和辐射安全评估的重要一步。退役的尾矿堆最终会干涸,变成硬化的人造块状阵列,对周围的生态系统产生负面影响。所建议的方法是在所提出的算法基础上实施的,这些算法用于确定测量条件的最佳选择,同时考虑到持续的山谷风的影响。为验证该方法,进行了实地研究,包括测量尾矿堆各点的氡-222 等效平衡体积活度。为此,使用了专门的方法和设备,从而可以确定空气中的氡浓度,并评估其从尾矿堆中散发的情况。使用专门软件和算法软件对获得的数据进行处理和分析,以便对数值进行详细分析和评估。
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引用次数: 0
Cellulose and cellulose derivatives in sustainable membrane development for oil/water separation 纤维素和纤维素衍生物在油/水分离可持续膜开发中的应用
Pub Date : 2024-03-13 DOI: 10.59429/ace.v7i2.1867
C. Chiam, Z. Kamin, Chi HueyNg, Farhana AbdLahin, R. Sarbatly
Cellulose is a natural polymer and most abundant organic substance on Earth. Inexhaustible hydroxyl groups on the cellulose surface allow derivatives of cellulose produced. This article discusses the recent progress of cellulose and cellulose derivatives in membrane development for oil/water separation. Functional groups that are available on the cellulose and its derivatives provide modification features to improve membrane wettability. Membranes with super wetting properties possess remarkable self-cleaning abilities which in turn can enhance permeation fluxes and extend membrane lifespan. However, the role of cellulose-based membranes in oily wastewater treatments is still in its early stages. This review article emphasizes on the development and modification of cellulose-based membranes for improvement of wettability, flux and separation efficiency, and the future directions of research.
纤维素是一种天然聚合物,也是地球上最丰富的有机物质。纤维素表面取之不尽的羟基使纤维素衍生物得以生产。本文讨论了纤维素及其衍生物在油/水分离膜开发方面的最新进展。纤维素及其衍生物上的官能团具有改性功能,可改善膜的润湿性。具有超强润湿性能的膜具有显著的自清洁能力,这反过来又能提高渗透通量并延长膜的使用寿命。然而,纤维素基膜在含油废水处理中的作用仍处于早期阶段。这篇综述文章强调了纤维素基膜的开发和改性,以改善其润湿性、通量和分离效率,以及未来的研究方向。
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引用次数: 0
Sigmatropic rearrangements in the synthesis of heterocyclic compounds and their functionalization 杂环化合物合成中的西格玛托普重排及其功能化
Pub Date : 2024-03-13 DOI: 10.59429/ace.v7i2.1869
Tubai Ghosh, S. Santra, G. Zyryanov, Brindaban C.Ranu
Sigmatropic rearrangements are well documented in the carbocyclic as well as heterocyclic chemistry. Various molecules have been obtained from easily accessible starting materials via involvement of sigmatropic rearrangements. This review presented a brief account of the synthesis of some important heterocyclic compounds and their functionalization involving sigmatropic rearrangements, particularly, [3,3]-, [2,3] and [1,5]-ones. The mechanism of some rearrangements has also been discussed.
在碳环和杂环化学中,西格玛托普重排都是有据可查的。各种分子都是通过参与西格玛重排从容易获得的起始材料中获得的。本综述简要介绍了一些重要杂环化合物的合成及其官能化过程,特别是[3,3]-、[2,3]和[1,5]-酮的西格玛重排。还讨论了一些重排的机理。
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引用次数: 0
Molecular docking, pharmacokinetic profiling and toxicity studies of 2-substituted benzimidazole derivatives against breast cancer 针对乳腺癌的 2-取代苯并咪唑衍生物的分子对接、药代动力学分析和毒性研究
Pub Date : 2024-03-11 DOI: 10.59429/ace.v7i2.1864
Jyoti Monga, Niladry SekharGhosh, Geeta Deswal, Ashwani K.Dhingra, Ajmer SinghGrewal
The most prevalent malignancy among women is breast cancer, which had almost 1.3 million new cases in 2020. It is the second most common cancer in the world, followed by lung cancer. The survival rate would be 99% if the cancerous tumour was limited to the breast. If the cancer migrated to neighbouring lymph nodes, the survival percentage would be 85% and it would drop to 27% if it spread to distant regions. In fact, the most prevalent breast cancer subtype is that caused by excessive estrogen levels. The enhancement of pertinent treatment techniques depends on the estrogen receptors (ER) in both healthy and pathological conditions. There are two primary types of ER, ERα and ERβ, which are each encoded by a different gene. ER status is the most important indicator of breast cancer prediction. To develop novel therapeutics for breast cancer, 30 newly designed benzimidazole compounds targeting the ER were docked. Among them, a compound with a glide score of −9.293 was discovered to be the leading compound. ADME investigations provided additional validation of the docking results. The pyrazole fused benzimidazole nucleus is therefore suggested as a potential pharmacophore for the development of innovative anticancer treatment for breast cancer.
女性最常见的恶性肿瘤是乳腺癌,2020 年新增病例近 130 万。它是世界上第二大常见癌症,其次是肺癌。如果癌症肿瘤仅限于乳房,生存率将达到 99%。如果癌细胞转移到邻近的淋巴结,存活率将为 85%;如果癌细胞扩散到远处,存活率将降至 27%。事实上,最常见的乳腺癌亚型是由雌激素水平过高引起的。如何提高治疗技术的针对性,取决于健康和病理状态下的雌激素受体(ER)。ER主要有两种类型,即ERα和ERβ,它们分别由不同的基因编码。ER状态是预测乳腺癌的最重要指标。为了开发治疗乳腺癌的新疗法,我们对接了 30 个新设计的针对 ER 的苯并咪唑化合物。在这些化合物中,发现了一种滑翔得分为-9.293的化合物,它是最主要的化合物。ADME 研究进一步验证了对接结果。因此,吡唑融合苯并咪唑核被认为是开发创新型乳腺癌抗癌疗法的潜在药源。
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引用次数: 0
Effects of initial turbidity and myco-coagulant dose on the effectiveness of the coagulation process in water treatment 初始浊度和菌凝剂剂量对水处理过程中混凝效果的影响
Pub Date : 2024-03-01 DOI: 10.59429/ace.v7i2.1546
R. Nedjai, Abdullah Al-Mamun, Md Zahangir Alam
High turbidity is a pollutant that requires coagulants to be removed from treated water and wastewater. This study was conducted to characterize and analyze the potential of myco-coagulant-producing fungus isolated from the moist area of a kitchen. Myco-coagulant production was carried out using solid-state fermentation using coco peat as a substrate. One factor-at-a-time analysis (OFAT) was carried out to assess the capacity of the produced myco-coagulant in various initial turbidities and myco-coagulant doses. The potential of myco-coagulant was tested using turbid synthetic water with different turbidity levels (50, 100, 150, 200, 250 and 300 NTU). The results showed that turbidity removal by the myco-coagulant was influenced by the initial turbidity. The coagulant was less efficient at low turbidity levels, which was approximately 5% for 50 NTU, while the highest was 52% for 300 NTU water. Furthermore, the results demonstrated that myco-coagulant could remove the highest possible turbidities on day 6 with all initial turbidity values studied in this work. Different myco-coagulant doses ranging from 1 to 10% (v/v) were also used to determine the optimum dose for effective flocculation. The highest turbidity removal of 57% could be obtained at an optimum coagulant dose of 4% (v/v). Like any other commercial coagulant, the residual turbidity value increased at a coagulant dose higher than the optimum dose of 4% (v/v).
高浊度是一种污染物,需要用混凝剂去除处理过的水和废水中的高浊度。本研究旨在描述和分析从厨房潮湿区域分离出来的产生霉菌凝固剂的真菌的潜力。以椰子泥炭为基质,采用固态发酵法生产菌胶凝剂。进行了一次因素分析(OFAT),以评估在不同初始浊度和菌凝剂剂量下生产的菌凝剂的能力。使用不同浊度水平(50、100、150、200、250 和 300 NTU)的浑浊合成水测试了菌凝剂的潜力。结果表明,霉菌凝固剂的除浊效果受初始浊度的影响。浊度较低时,混凝剂的去除率较低,50 NTU 水的去除率约为 5%,而 300 NTU 水的去除率最高,为 52%。此外,研究结果表明,在第 6 天,霉菌凝固剂可以去除本研究中所有初始浊度值可能达到的最高浊度。为确定有效絮凝的最佳剂量,还使用了 1% 至 10% (v/v) 不等的不同霉凝剂剂量。最佳混凝剂剂量为 4%(v/v)时,浊度去除率最高,可达 57%。与其他商用混凝剂一样,当混凝剂剂量高于 4% (v/v) 的最佳剂量时,残余浊度值会增加。
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引用次数: 0
A system dynamic modeling to evaluate fluidized bed dryers under tempering and recirculation strategies 评估回火和再循环策略下流化床干燥器的系统动态模型
Pub Date : 2024-01-10 DOI: 10.24294/ace.v7i1.3276
R. Amantea, Daniele Sarri, Giuseppe Rossi
Grain drying control strategies aim for a rational energy use and a final product with low breakage levels. However, an experimental approach may be prohibitive due to the costs, scale, and theoretical complexity of this operation. The simulation environment is suitable to design equipment’s and plan operations strategies with low cost and high certainty. This work utilized system dynamics modelling to quantify the percentage of product breakage during drying in fluidized bed dryers under recirculation and tempering strategies. A sensitivity analysis of the model’s input parameters including different fractions of recirculation was performed, showing their effects on drying and post-drying product quality. Finally, we present optimizations from different objectives of drying operations. The recirculation strategy worked as an attenuator to the drying rates and combined with tempering strategy reached a minimum breakage level.
谷物干燥控制策略的目标是合理使用能源,并使最终产品的破损程度较低。然而,由于这种操作的成本、规模和理论复杂性,实验方法可能会令人望而却步。模拟环境适用于以低成本和高确定性来设计设备和规划操作策略。这项工作利用系统动力学建模来量化流化床干燥器在再循环和回火策略下干燥过程中产品破损的百分比。我们对模型的输入参数(包括不同的再循环比例)进行了敏感性分析,显示了这些参数对干燥和干燥后产品质量的影响。最后,我们介绍了不同干燥操作目标的优化情况。再循环策略是干燥速率的衰减器,与调质策略相结合可达到最低破损水平。
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引用次数: 0
Enhancing the engineering properties of gypseous soils by adding the Anthan polymers 通过添加 Anthan 聚合物提高石膏土的工程特性
Pub Date : 2024-01-09 DOI: 10.24294/ace.v7i1.2828
N. A. Hassan, Hassan Ali Ahmed, Akram Khalaf Mohammed
Large areas of soil in Iraq are formed up of gypsum soil. As a result, understanding the habits of this soil and its treatment approach is critical, because its current solution is to replace gypsum soil before beginning any building activity. This study used gypsum soil from Tikrit City, which has a gypsum concentration that is around 38%, and the goal of the study is to illustrate the impact of the polymer on the gypsum soil parameters. Simultaneously, researchers are investigating the beneficial effects of polymers on the behavior of gypsum soil. The percentages of the polymer additive (5%, 7.5%, 10%, 12.5%, and 15%) were weight percentages, while the soil tests were chemical, physical, and engineering. When the percentage of additive was increased from 0% to 15%, Soil engineering characteristics enhanced the collapse of the from 5.11 to 1.21, cohesion improved from (28.98 KN/m2) to (51.16 KN/m2), and angles of internal friction decreased from 33.190 to 38.850.
伊拉克的大片土壤是由石膏土构成的。因此,了解这种土壤的习性及其处理方法至关重要,因为目前的解决方案是在开始任何建筑活动之前更换石膏土。这项研究使用了提克里特市的石膏土壤,其石膏浓度约为 38%,研究的目的是说明聚合物对石膏土壤参数的影响。同时,研究人员还在调查聚合物对石膏土壤行为的有利影响。聚合物添加剂的百分比(5%、7.5%、10%、12.5% 和 15%)是重量百分比,而土壤测试是化学、物理和工程测试。当添加剂的百分比从 0% 增加到 15%时,土壤工程特性从 5.11 提高到 1.21,内聚力从(28.98 KN/m2)提高到(51.16 KN/m2),内摩擦角从 33.190 减小到 38.850。
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引用次数: 0
Assessing the potentials of rice straws as a solid fuel for the production of clean energy 评估稻草作为固体燃料生产清洁能源的潜力
Pub Date : 2024-01-09 DOI: 10.24294/ace.v7i1.3097
Abu Md. Mehdi Hassan, Chengxi Yao, Muhammad Asif, Md. Ripaj Uddin, M. A. Al-Mansur, Mayeen Uddin Khandaker, Farzana Yasmin
Environmental contamination increased as a result of the extensive use of fossil fuels, large-scale industrialization, and population growth. It has become an urgent need to reduce carbon emissions for environmental sustainability. The revolution in renewable energy may be the best option for lowering carbon emissions. In this research, rice straw was considered as a possible wellspring of bioenergy production. The aim of the study is to determine the best way to use biomass by comprehending its thermal qualities. Several state-of-the-art techniques were used to characterize the rice straws to understand their potential as a solid fuel for clean energy production. Elemental analysis reveals the predominance of carbon and oxygen content while nitrogen and sulfur are minor constituents in the studied rice straws. Fourier transform infrared (FTIR) spectroscopy analysis suggested the presence of cellulosic and ligneous constituents. Pyrolysis is one of the appropriate choices to make esteem expansion and contributes to biomass utilization. The thermogravimetric analysis (TGA) analyses revealed that rice straw pyrolysis has occurred in three distinct stages i.e., dehydration, active pyrolysis, and passive pyrolysis. The differential thermogravimetric graph (DTG) depicts how the temperature peak at the greatest weight loss shifts as the heating rate rises. Based on the characterization and subsequent analysis, it can be concluded that rice straw is a critical biomass and suitable to be used in clean energy production and maintain environmental sustainability.
由于化石燃料的广泛使用、大规模工业化和人口增长,环境污染日益严重。为了环境的可持续发展,减少碳排放已成为当务之急。可再生能源革命可能是降低碳排放的最佳选择。在这项研究中,稻草被认为是生物能源生产的可能源泉。研究的目的是通过了解生物质的热能质量,确定使用生物质的最佳方法。研究人员使用了几种最先进的技术对稻草进行表征,以了解其作为清洁能源生产固体燃料的潜力。元素分析表明,在所研究的稻草中,碳和氧含量占主导地位,而氮和硫则是次要成分。傅立叶变换红外光谱(FTIR)分析表明存在纤维素和木质成分。热解是扩大价值的适当选择之一,有助于生物质的利用。热重分析(TGA)显示,稻草热解分为三个不同阶段,即脱水、主动热解和被动热解。微分热重图 (DTG) 描述了重量损失最大时的温度峰值是如何随着加热速率的增加而移动的。根据表征和后续分析,可以得出结论:稻草是一种重要的生物质,适合用于清洁能源生产,并能保持环境的可持续发展。
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引用次数: 0
Biocatalysts for biomethanol production: Advancements and future prospects 生产生物甲醇的生物催化剂:进展与前景
Pub Date : 2024-01-08 DOI: 10.24294/ace.v7i1.2646
R. K. Srivastava, P. Sarangi, U. K. Sahoo, Tarun Kumar Thakur, Harikesh B. Singh, Sanjukta Subudhi
Biomethanol, a renewable and sustainable alternative to traditional fossil-fuel-derived methanol, has garnered considerable attention as a potential solution to mitigate greenhouse gas emissions and dependence on non-renewable resources. The utilization of biocatalysts in biomethanol production offers a promising avenue to achieve environmentally friendly and economically viable processes. Paper highlights the biocatalytic pathways involved in biomethanol synthesis. Particular emphasis is placed on microbial biocatalysts, such as methanogenic archaea and certain bacteria, which possess the unique capability of converting carbon dioxide and hydrogen into methanol through a series of enzymatic reactions. Additionally, enzyme-based systems derived from various microorganisms and genetically engineered organisms are also discussed as potential biocatalysts for biomethanol synthesis. Paper also delves into the current challenges and limitations faced in harnessing biocatalysts for biomethanol production. These challenges include substrate availability, low conversion rates, enzyme stability, and process scalability. Several strategies to address these issues are highlighted, including metabolic engineering, synthetic biology, and bioprocess optimization techniques. The advantages of utilizing biocatalysts for biomethanol production are outlined. Biocatalytic routes offer the advantage of operating under mild conditions, which reduces energy consumption and minimizes the production of unwanted by-products. Furthermore, the utilization of renewable feedstocks, such as carbon dioxide captured from industrial emissions or waste streams, enhances the sustainability of the process. The final section discusses future prospects and potential research directions in the field of biocatalytic biomethanol production. Advances in biotechnology, omics technologies, and computational modeling are poised to accelerate the discovery and optimization of novel biocatalysts, thereby unlocking the full potential of biomethanol as a sustainable fuel and chemical precursor. The use of biocatalysts for biomethanol production offers an attractive approach to establish a green and circular economy. With ongoing research and technological advancements, the field holds significant promise for reducing carbon emissions and transitioning towards a more sustainable energy landscape. However, to fully realize the potential of biocatalytic biomethanol production, interdisciplinary collaboration and concerted efforts are required to address existing challenges.
生物甲醇是传统化石燃料甲醇的可再生和可持续替代品,作为减少温室气体排放和对不可再生资源依赖的潜在解决方案,生物甲醇已经引起了广泛关注。在生物甲醇生产中利用生物催化剂为实现环境友好型和经济可行型工艺提供了一条大有可为的途径。论文重点介绍了生物甲醇合成所涉及的生物催化途径。论文特别强调了微生物生物催化剂,如产甲烷古细菌和某些细菌,它们具有通过一系列酶促反应将二氧化碳和氢转化为甲醇的独特能力。此外,论文还讨论了从各种微生物和基因工程生物中提取的基于酶的系统,将其作为生物甲醇合成的潜在生物催化剂。论文还深入探讨了目前利用生物催化剂生产生物甲醇所面临的挑战和限制。这些挑战包括底物的可用性、低转化率、酶的稳定性和工艺的可扩展性。重点介绍了解决这些问题的几种策略,包括代谢工程、合成生物学和生物工艺优化技术。概述了利用生物催化剂生产生物甲醇的优势。生物催化路线具有在温和条件下操作的优势,可降低能耗并最大限度地减少不需要的副产品的产生。此外,利用可再生原料(如从工业排放或废物流中捕获的二氧化碳)可增强工艺的可持续性。最后一节讨论了生物催化生物甲醇生产领域的未来前景和潜在研究方向。生物技术、omics 技术和计算建模的进步将加速新型生物催化剂的发现和优化,从而释放生物甲醇作为可持续燃料和化学前体的全部潜力。使用生物催化剂生产生物甲醇为建立绿色和循环经济提供了一种极具吸引力的方法。随着研究的不断深入和技术的不断进步,该领域在减少碳排放和向更可持续的能源格局过渡方面大有可为。然而,要充分发挥生物催化生物甲醇生产的潜力,需要跨学科合作和共同努力来应对现有挑战。
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引用次数: 0
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Applied Chemical Engineering
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