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Functional and radiological outcomes of multiple dorsal carpometacarpal fracture dislocations treated with open reduction and internal fixation. 切开复位内固定治疗多发性掌背骨折脱位的功能和影像学结果。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-08-01 DOI: 10.5606/ehc.2019.64279
Mehmet Ali Talmaç, Mehmet Akif Görgel, Ferdi Dırvar, Okan Tok, Hacı Mustafa Özdemir

Objectives: This study aims to evaluate the clinical and radiological results of patients with multiple dorsal carpometacarpal (CMC) joint fracture dislocations treated with open reduction and internal fixation (ORIF).

Patients and methods: We evaluated 14 patients (12 males, 2 females; mean age 35.1 years; range, 22 to 64 years) between January 2013 and December 2017. Our main outcome measurements were the Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) score, loss of grip strength, limitation of range of motion (ROM), and Kellgren-Lawrence osteoarthritis classification identified with radiographs and computed tomography images.

Results: The mean QuickDASH scores at seventh week and third month were 73.57 (range, 65-90) and 29.11 (range, 25-42.5), respectively. The mean QuickDASH score at seventh, ninth, and 12th month, and final follow-up was 4.64 (range, 0-30) and the QuickDASH score at these follow-up points was not 0 for only three patients. The mean loss of grip strength was 32.14% and two patients (14.29%) had limitation of ROM in third proximal interphalangeal joint at final follow-up. Four patients had grade I, nine patients had grade II, and one patient had grade III osteoarthritis according to Kellgren-Lawrence classification at final follow-up.

Conclusion: Although functional results demonstrated that multiple CMC joint fracture dislocations can be treated with ORIF, the high rate of osteoarthritis is a disadvantage.

目的:本研究旨在评价切开复位内固定(ORIF)治疗多发性腕掌骨背(CMC)关节骨折脱位的临床和影像学结果。患者和方法:我们评估了14例患者(男性12例,女性2例;平均年龄35.1岁;从2013年1月到2017年12月,年龄从22岁到64岁不等。我们的主要结果测量是手臂、肩膀和手的快速残疾(QuickDASH)评分,握力丧失,活动范围受限(ROM),以及通过x线片和计算机断层扫描图像确定的Kellgren-Lawrence骨关节炎分类。结果:第7周和第3个月的平均QuickDASH评分分别为73.57(范围65-90)和29.11(范围25-42.5)。第7个月、第9个月和第12个月以及最终随访的平均QuickDASH评分为4.64(范围0-30),只有3例患者在这些随访点的QuickDASH评分不为0。最后随访时,平均握力丧失32.14%,2例(14.29%)患者第三近端指间关节活动受限。根据最后随访时kelgren - lawrence分级,4例患者为I级,9例患者为II级,1例患者为III级骨关节炎。结论:虽然功能结果表明,ORIF可以治疗多发性CMC关节骨折脱位,但其较高的骨关节炎发生率是一个缺点。
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引用次数: 2
The positive impact of platelet-derived growth factor on the repair of full-thickness defects of articular cartilage. 血小板源性生长因子对关节软骨全层缺损修复的积极影响。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-08-01 DOI: 10.5606/ehc.2019.64018
Sezgin Sarban, Hasan Tabur, Z Füsun Baba, U Erdem Işıkan

Objectives: This study aims to investigate the potential use and histological effects of the local administration of platelet-derived growth factor (PDGF) in the repair of full-thickness osteochondral defects in articular cartilage in an animal model.

Materials and methods: Twenty-four adolescent 18-week-old New Zealand White rabbits with an average weight of 2500 g (range, 1600 g to 3200 g) were used in the study. The rabbits were randomly divided into three groups (n=8) as the control group (group A) and two experimental groups (groups B and C). Defects of cylindrical full-thickness (3.5 mm wide, 4 mm deep) were created in the weight-bearing area of the right knee medial femoral condyles. In group A, the defect was left empty. In group B, the defect was filled with a collagen sponge. In group C, the defect was filled with a collagen sponge impregnated with PDGF. All rabbits were followed-up for 12 weeks. Right knee medial femoral condyles were used for macroscopic and histological analyses.

Results: At macroscopic level, the repair tissue was similar to normal adjacent cartilage at 12 weeks in group C. The surface of the repair tissue in group C was smoother and more regular compared to groups A and B. The total histological score of defects in group C was statistically significantly superior compared to groups A and B (p<0.05). Matrix staining and immunostaining of collagen type 2 were stronger in group C compared to the other groups, indicating the presence of a tissue similar to a normal cartilage.

Conclusion: Platelet-derived growth factor can induce repair in full-thickness defects of articular cartilage in an animal model. Thus, this study demonstrates the potential use of PDGF for full-thickness osteochondral defects.

目的:本研究旨在探讨局部给药血小板衍生生长因子(PDGF)在动物模型中修复关节软骨全层骨软骨缺损的潜在用途和组织学效果。材料与方法:选取24只18周龄青春期新西兰大白兔,平均体重2500 g(范围1600 ~ 3200g)。将实验兔随机分为3组(n=8),分别为对照组(A组)和实验组(B、C组),在右膝股骨内侧髁负重区制造圆柱状全层缺损(宽3.5 mm,深4mm)。在A组,缺陷是空的。B组用胶原蛋白海绵填充缺损。C组用PDGF浸渍的胶原海绵填充缺损。所有家兔均随访12周。右膝股骨内侧髁进行宏观和组织学分析。结果:在宏观水平上,C组修复组织在12周时与正常相邻软骨相似,C组修复组织表面较A、B组更光滑、更规则,C组缺损的总组织学评分较A、B组有统计学意义(p)。结论:血小板源性生长因子在动物模型中可诱导关节软骨全层缺损的修复。因此,本研究证明了PDGF在全层骨软骨缺损中的潜在应用。
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引用次数: 4
Biochemical markers decrease and increase disproportionally in A1 pulley tissue of type 2 diabetic trigger finger patients. 2型糖尿病扳机指患者A1滑轮组织生化指标呈不成比例的升高和降低。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-08-01 DOI: 10.5606/ehc.2019.66112
Nazmi Bülent Alp, Gökhan Akdağ, Gülsüm Karduz, Kübra Vardar, Uğur Aksu

Objectives: This study aims to detect the levels of some biochemical markers in A1 pulley tissue of type 2 diabetic trigger finger patients to enlighten the mechanisms leading to cellular complications.

Patients and methods: The study included 35 trigger finger patients (5 males, 30 females; mean age 53.9±9.15 years; range, 37 to 71 years). We measured total thiol (total-SH) levels to determine the status of the non-enzymatic antioxidant defense system and advanced oxidation protein product (AOPP) levels to determine levels of oxidative protein modification in pulley tissues of trigger finger patients with or without diabetes. Extracellular matrix degradation was assessed by measuring levels of sialic acid (SA) in the pulley tissue.

Results: Total-SH values for the groups with and without diabetes were 22.7±1.6 vs. 38.9±5.2 nmol/mg protein, respectively, while AOPP values were 472.5±131.6 vs.175.6±9.9 mmol/g protein, respectively. The SA levels of diabetic and nondiabetic patients were 0.4±0.0 vs. 0.63±0.1 nmol/mg protein, respectively.

Conclusion: Our results revealed that tissue SA levels and tissue SH levels decreased and AOPP levels increased disproportionally in the A1 pulley tissue of diabetic patients, which may indicate the role of oxidative protein damage and extracellular matrix changes in diabetic trigger finger etiology.

目的:本研究旨在检测2型糖尿病扳机指患者A1滑轮组织中一些生化标志物的水平,以揭示细胞并发症的发生机制。患者与方法:35例扳机指患者(男5例,女30例;平均年龄53.9±9.15岁;范围:37至71岁)。我们测量了总硫醇(total- sh)水平,以确定非酶抗氧化防御系统的状态,并测量了高级氧化蛋白产物(AOPP)水平,以确定有或无糖尿病的扳机指患者滑轮组织中氧化蛋白修饰的水平。通过测量滑轮组织中唾液酸(SA)的水平来评估细胞外基质降解。结果:糖尿病组和非糖尿病组的总sh值分别为22.7±1.6和38.9±5.2 nmol/mg蛋白,AOPP值分别为472.5±131.6和175.6±9.9 mmol/g蛋白。糖尿病和非糖尿病患者的SA水平分别为0.4±0.0和0.63±0.1 nmol/mg蛋白。结论:糖尿病患者A1皮带轮组织中SA水平和SH水平明显降低,AOPP水平明显升高,这可能提示氧化蛋白损伤和细胞外基质改变在糖尿病扳机指发病机制中的作用。
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引用次数: 1
Modified percutaneous fixation for displaced intra-articular calcaneal fractures. 改良经皮内固定治疗移位的跟骨关节内骨折。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-08-01 DOI: 10.5606/ehc.2019.66386
Emre Baca, Alican Koluman

Objectives: This study aims to review the results of surgically treated displaced intra-articular calcaneal fractures with a fast, less complicated, and modified percutaneous technique.

Patients and methods: This retrospective study included 114 patients (86 males, 28 females; mean age 39 years; range, 16 to 66 years) admitted to our clinic for calcaneal fractures between May 2012 and June 2016 and operated using closed reduction and percutaneous fixation with two crossed Schanz pins. Trauma type, additional injuries, medical comorbidities, pre- and postoperative period, duration of operation, time to bone healing, complications, postoperative functional and radiological results were evaluated.

Results: The increase in the postoperative Bohler's angle measurements was statistically significant compared to preoperative values (p=0.001; p<0.01). According to Sanders classification, seven feet (5.3%) were type II, 76 feet (57.57%) were type III, and 49 feet (37.12%) were type IV. The mean American Orthopaedic Foot and Ankle Society (AOFAS) score was 80.4 (range, 47 to 92). According to Sanders classification, the mean AOFAS scores were 81.25 for type II, 81.88 for type III, and 80.19 for type IV. Mean duration of operation was 8±1.5 minutes.

Conclusion: Modified percutaneous fixation can give good results, even when open reduction is contraindicated. Maintaining the alignment and elevating the depressed intra-articular fragment may be sufficient for good mid-term results without anatomic reduction.

目的:本研究旨在回顾一种快速、简单、改良的经皮技术治疗移位的跟骨关节内骨折的结果。患者与方法:本研究纳入114例患者,其中男性86例,女性28例;平均年龄39岁;年龄16至66岁)于2012年5月至2016年6月因跟骨骨折入院,采用闭合复位和经皮两根交叉Schanz针固定。评估创伤类型、附加损伤、医疗合并症、术前和术后时间、手术时间、骨愈合时间、并发症、术后功能和放射学结果。结果:与术前相比,术后勃勒角测量值的增加具有统计学意义(p=0.001;结论:改良的经皮内固定可以获得良好的效果,即使有切开复位的禁忌。维持对准和抬高凹陷的关节内碎片可能足以获得良好的中期结果,而无需解剖复位。
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引用次数: 11
Suprapatellar approach for fractures of the tibia: Does the fracture level matter? 髌骨上入路治疗胫骨骨折:骨折水平重要吗?
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-04-01 DOI: 10.5606/ehc.2019.63487
Özgür Çiçekli, Alauddin Kochai, Erhan Şükür, Ali Murat Başak, Alper Kurtoğlu, Mehmet Türker

Objectives: This study aims to evaluate proximal, shaft, and distal tibial fractures treated with suprapatellar (SP) tibial intramedullary nailing (IMN) in terms of alignment, healing, and patellofemoral (PF) pain.

Patients and methods: The study included 58 patients (41 males, 17 females; mean age 42.9 years; range, 18 to 75 years) treated via the SP approach in semiextention. Suprapatellar IMN surgeries were performed by two surgeons. After a minimum of 12 months of follow-up, patients' genders, ages, limb sides, fracture types, and classifications were recorded. Fracture reduction accuracy, angulation, PF arthritis, healing time, complications, and nonunions were analyzed. Anterior knee pain, visual analog scale (VAS), and Lysholm knee scoring scale were used as clinical measurements.

Results: Seventeen fractures were in the proximal third, while 22 were in the middle third and 19 were in the distal third of the tibia. The mean healing time was 7.14 months (range, 4 to 13 months); differences in healing time between fracture locations were not statistically significant (p=0.83). The mean follow-up duration was 19.83 months (range, 12 to 30 months); there were no statistically significant differences in follow-up times in terms of fracture sites (p=0.51). The VAS score for the knee was 0 in 49 patients (84.5%) and <3 in nine patients (15.5%). The Lysholm score differences between the fracture location groups were not statistically significant (p=0.33).

Conclusion: Suprapatellar tibial IMN can be applicable to extra-articular tibial fractures in all locations. Providing easy anatomic reduction in semiextention, convenient fluoroscopic imaging, safety for the PF joint, acceptable anterior knee pain, and satisfactory functional outcomes render SP approach more feasible.

目的:本研究旨在评估髌上(SP)胫骨髓内钉(IMN)治疗胫骨近端、胫骨骨干和胫骨远端骨折在对齐、愈合和髌骨股骨(PF)疼痛方面的效果。患者与方法:共纳入58例患者,其中男性41例,女性17例;平均年龄42.9岁;范围,18至75岁),采用半延伸的SP方法治疗。髌上IMN手术由两名外科医生进行。在至少12个月的随访后,记录患者的性别、年龄、肢体侧面、骨折类型和分类。分析骨折复位精度、成角、PF关节炎、愈合时间、并发症和骨不连。临床测量采用膝关节前侧疼痛、视觉模拟量表(VAS)和Lysholm膝关节评分量表。结果:胫骨近三分之一骨折17例,胫骨中三分之一骨折22例,胫骨远三分之一骨折19例。平均愈合时间7.14个月(范围4 ~ 13个月);骨折部位愈合时间差异无统计学意义(p=0.83)。平均随访时间为19.83个月(12 ~ 30个月);骨折部位随访时间差异无统计学意义(p=0.51)。49例患者膝关节VAS评分为0分,占84.5%。结论:髌上胫骨IMN适用于所有部位的胫骨关节外骨折。半伸位解剖复位容易,透视成像方便,PF关节安全,膝关节前侧疼痛可接受,功能结果满意,使得SP入路更可行。
{"title":"Suprapatellar approach for fractures of the tibia: Does the fracture level matter?","authors":"Özgür Çiçekli,&nbsp;Alauddin Kochai,&nbsp;Erhan Şükür,&nbsp;Ali Murat Başak,&nbsp;Alper Kurtoğlu,&nbsp;Mehmet Türker","doi":"10.5606/ehc.2019.63487","DOIUrl":"https://doi.org/10.5606/ehc.2019.63487","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to evaluate proximal, shaft, and distal tibial fractures treated with suprapatellar (SP) tibial intramedullary nailing (IMN) in terms of alignment, healing, and patellofemoral (PF) pain.</p><p><strong>Patients and methods: </strong>The study included 58 patients (41 males, 17 females; mean age 42.9 years; range, 18 to 75 years) treated via the SP approach in semiextention. Suprapatellar IMN surgeries were performed by two surgeons. After a minimum of 12 months of follow-up, patients' genders, ages, limb sides, fracture types, and classifications were recorded. Fracture reduction accuracy, angulation, PF arthritis, healing time, complications, and nonunions were analyzed. Anterior knee pain, visual analog scale (VAS), and Lysholm knee scoring scale were used as clinical measurements.</p><p><strong>Results: </strong>Seventeen fractures were in the proximal third, while 22 were in the middle third and 19 were in the distal third of the tibia. The mean healing time was 7.14 months (range, 4 to 13 months); differences in healing time between fracture locations were not statistically significant (p=0.83). The mean follow-up duration was 19.83 months (range, 12 to 30 months); there were no statistically significant differences in follow-up times in terms of fracture sites (p=0.51). The VAS score for the knee was 0 in 49 patients (84.5%) and <3 in nine patients (15.5%). The Lysholm score differences between the fracture location groups were not statistically significant (p=0.33).</p><p><strong>Conclusion: </strong>Suprapatellar tibial IMN can be applicable to extra-articular tibial fractures in all locations. Providing easy anatomic reduction in semiextention, convenient fluoroscopic imaging, safety for the PF joint, acceptable anterior knee pain, and satisfactory functional outcomes render SP approach more feasible.</p>","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37069061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Selective arterial embolization as neoadjuvant treatment in hip pseudotumors. 选择性动脉栓塞作为髋关节假性肿瘤的新辅助治疗。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-04-01 DOI: 10.5606/ehc.2019.65011
Mehmet Ali Tokgöz, Andrea Sambri, Giuseppe Rossi, Giuseppe Bianchi, Davide Maria Donati

Objectives: This study aims to investigate the significance of selective arterial embolization (SAE) as neoadjuvant for the treatment of pseudotumor (PT) associated with hip arthroplasty and present our case series including all the known bearing techniques.

Patients and methods: This retrospective study included 16 patients (9 males, 7 females; mean age 75.5 years; range, 55 to 87 years) affected by hip PT. Seven patients were treated only surgically without any adjuvant treatment (group A), while nine patients were performed preoperative SAE (group B). Pseudotumors were grouped according to magnetic resonance imaging and computed tomography (CT) classifications. Durations of all operations and number of blood units given intra- and postoperatively were recorded.

Results: Although embolization did not change the amount of intraoperative bleeding (p=0.619), a common vascular network leading to PT was observed in all patients in angiography. Group A's mean duration of operation was shorter than group B (p=0.03); however, this condition was attributed to larger and more complex lesions of patients who underwent embolization. According to CT classification, blood loss was more and duration of operation was longer in severe stages (p=0.046 and p=0.035, respectively).

Conclusion: Successful demonstration of vascular network in patients with PT strengthens the idea that SAE technique may be used particularly in severe cases according to CT classification. Our findings suggest that PT may develop in all commonly used bearings.

目的:本研究旨在探讨选择性动脉栓塞(SAE)作为髋关节置换术相关假性肿瘤(PT)新辅助治疗的意义,并介绍我们的病例系列,包括所有已知的承载技术。患者和方法:本回顾性研究纳入16例患者(男9例,女7例;平均年龄75.5岁;7例患者仅接受手术治疗,未进行任何辅助治疗(A组),9例患者术前行SAE (B组)。假肿瘤根据磁共振成像和计算机断层扫描(CT)分类进行分组。记录所有手术持续时间及术中、术后输血单位数。结果:栓塞术虽未改变术中出血量(p=0.619),但所有患者血管造影均观察到导致PT的共同血管网络。A组平均手术时间短于B组(p=0.03);然而,这种情况归因于接受栓塞治疗的患者的更大更复杂的病变。CT分型显示,重症出血量多、手术时间长(p=0.046、p=0.035)。结论:在PT患者中成功显示血管网络加强了SAE技术可以应用的想法,特别是在根据CT分类的严重病例中。我们的研究结果表明,PT可能在所有常用轴承中发展。
{"title":"Selective arterial embolization as neoadjuvant treatment in hip pseudotumors.","authors":"Mehmet Ali Tokgöz,&nbsp;Andrea Sambri,&nbsp;Giuseppe Rossi,&nbsp;Giuseppe Bianchi,&nbsp;Davide Maria Donati","doi":"10.5606/ehc.2019.65011","DOIUrl":"https://doi.org/10.5606/ehc.2019.65011","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate the significance of selective arterial embolization (SAE) as neoadjuvant for the treatment of pseudotumor (PT) associated with hip arthroplasty and present our case series including all the known bearing techniques.</p><p><strong>Patients and methods: </strong>This retrospective study included 16 patients (9 males, 7 females; mean age 75.5 years; range, 55 to 87 years) affected by hip PT. Seven patients were treated only surgically without any adjuvant treatment (group A), while nine patients were performed preoperative SAE (group B). Pseudotumors were grouped according to magnetic resonance imaging and computed tomography (CT) classifications. Durations of all operations and number of blood units given intra- and postoperatively were recorded.</p><p><strong>Results: </strong>Although embolization did not change the amount of intraoperative bleeding (p=0.619), a common vascular network leading to PT was observed in all patients in angiography. Group A's mean duration of operation was shorter than group B (p=0.03); however, this condition was attributed to larger and more complex lesions of patients who underwent embolization. According to CT classification, blood loss was more and duration of operation was longer in severe stages (p=0.046 and p=0.035, respectively).</p><p><strong>Conclusion: </strong>Successful demonstration of vascular network in patients with PT strengthens the idea that SAE technique may be used particularly in severe cases according to CT classification. Our findings suggest that PT may develop in all commonly used bearings.</p>","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37067898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Wear pattern on the bottom of tennis shoe after surgical repair of acute Achilles tendon rupture: 22-year follow-up. 急性跟腱断裂手术修复后网球鞋底磨损模式:22年随访。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-04-01 DOI: 10.5606/ehc.2019.002
O Şahap Atik

In this article, we report a 67-year-old male patient who had a different wear pattern on the bottom of his tennis shoe after surgical repair of acute Achilles tendon rupture with 22-year follow-up. The wear pattern was well-matched with dynamic pedobarography. In left shoe with less total contact area and higher pressure values, there was more wear compared to right shoe.

在这篇文章中,我们报告了一位67岁的男性患者,在手术修复急性跟腱断裂后,他的网球鞋底部有不同的磨损模式,并进行了22年的随访。磨损模式与动态足检相吻合。总接触面积小、压力值高的左鞋比右鞋磨损大。
{"title":"Wear pattern on the bottom of tennis shoe after surgical repair of acute Achilles tendon rupture: 22-year follow-up.","authors":"O Şahap Atik","doi":"10.5606/ehc.2019.002","DOIUrl":"https://doi.org/10.5606/ehc.2019.002","url":null,"abstract":"<p><p>In this article, we report a 67-year-old male patient who had a different wear pattern on the bottom of his tennis shoe after surgical repair of acute Achilles tendon rupture with 22-year follow-up. The wear pattern was well-matched with dynamic pedobarography. In left shoe with less total contact area and higher pressure values, there was more wear compared to right shoe.</p>","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37067905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Are peripheral nerve blocks effective in pain control of pediatric orthopedic tumor surgery? 周围神经阻滞在小儿骨科肿瘤手术疼痛控制中有效吗?
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-04-01 DOI: 10.5606/ehc.2019.62395
Güldeniz Argun, Göze Çayırlı, Güray Toğral, Murat Arıkan, Süheyla Ünver

Objectives: This study aims to evaluate the efficacy of ultrasound (US)-guided peripheral nerve blocks in postoperative analgesia after pediatric orthopedic tumor surgery.

Patients and methods: This retrospective study included 108 children (64 boys, 44 girls, mean age 10.23 years; range, 2 to 18 years) who were performed orthopedic tumor surgery under general anesthesia. The children were divided into two groups as those who were performed nerve block for postoperative pain control (group 1, n=54) and those who were performed intravenous analgesic (group 2, n=54). In group 1, nerve blocks were performed with bupivacaine 0.25%. In group 2, intraoperative acetaminophen 15 mg/kg was performed intravenously. Postoperative visual analog scale (VAS) scores, time to pain onset, nausea, vomiting, total analgesic consumption in 24 hours, and complications were recorded at first, second, sixth and 24th hours.

Results: Visual analog scale scores were higher in group 2 than group 1 at first, second, and sixth hours, but were not different at 24th hour. Mean time to pain onset was 10.2 hours in group 1 and 1.8 hours in group 2 (p<0.05). Mean time to pain onset and VAS values at first, second, sixth and 24th hours did not differ between nerve block types. Nausea and vomiting rates were not different between groups 1 and 2 (18.51% and 16.66%, respectively; p=0.4). Total analgesic consumption in 24 hours was higher in group 2 compared to group 1 (1.7 and 0.07 mg/kg, respectively; p<0.05).

Conclusion: Pain-free periods extending up to 10 hours provided by US-guided peripheral nerve blocks may help recovery while reducing postoperative analgesic use and their side effects.

目的:本研究旨在评价超声引导下周围神经阻滞在小儿骨科肿瘤手术后镇痛中的作用。患者和方法:本回顾性研究纳入108例儿童,其中男孩64例,女孩44例,平均年龄10.23岁;范围,2至18岁),在全身麻醉下进行骨科肿瘤手术。将患儿分为术后神经阻滞镇痛组(1组,n=54)和静脉镇痛组(2组,n=54)。第1组采用0.25%布比卡因进行神经阻滞。2组术中静脉滴注对乙酰氨基酚15 mg/kg。记录术后第1、2、6、24小时视觉模拟评分(VAS)、疼痛发生时间、恶心、呕吐时间、24小时内镇痛药总用量及并发症。结果:第1、2、6 h组视觉模拟量表评分高于第1、2、6 h组,第24 h组差异无统计学意义。1组平均疼痛发作时间为10.2小时,2组为1.8小时(结论:us引导下的周围神经阻滞提供的无痛期可达10小时,有助于恢复,同时减少术后镇痛药的使用及其副作用。
{"title":"Are peripheral nerve blocks effective in pain control of pediatric orthopedic tumor surgery?","authors":"Güldeniz Argun,&nbsp;Göze Çayırlı,&nbsp;Güray Toğral,&nbsp;Murat Arıkan,&nbsp;Süheyla Ünver","doi":"10.5606/ehc.2019.62395","DOIUrl":"https://doi.org/10.5606/ehc.2019.62395","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to evaluate the efficacy of ultrasound (US)-guided peripheral nerve blocks in postoperative analgesia after pediatric orthopedic tumor surgery.</p><p><strong>Patients and methods: </strong>This retrospective study included 108 children (64 boys, 44 girls, mean age 10.23 years; range, 2 to 18 years) who were performed orthopedic tumor surgery under general anesthesia. The children were divided into two groups as those who were performed nerve block for postoperative pain control (group 1, n=54) and those who were performed intravenous analgesic (group 2, n=54). In group 1, nerve blocks were performed with bupivacaine 0.25%. In group 2, intraoperative acetaminophen 15 mg/kg was performed intravenously. Postoperative visual analog scale (VAS) scores, time to pain onset, nausea, vomiting, total analgesic consumption in 24 hours, and complications were recorded at first, second, sixth and 24th hours.</p><p><strong>Results: </strong>Visual analog scale scores were higher in group 2 than group 1 at first, second, and sixth hours, but were not different at 24th hour. Mean time to pain onset was 10.2 hours in group 1 and 1.8 hours in group 2 (p<0.05). Mean time to pain onset and VAS values at first, second, sixth and 24th hours did not differ between nerve block types. Nausea and vomiting rates were not different between groups 1 and 2 (18.51% and 16.66%, respectively; p=0.4). Total analgesic consumption in 24 hours was higher in group 2 compared to group 1 (1.7 and 0.07 mg/kg, respectively; p<0.05).</p><p><strong>Conclusion: </strong>Pain-free periods extending up to 10 hours provided by US-guided peripheral nerve blocks may help recovery while reducing postoperative analgesic use and their side effects.</p>","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37067902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Surgical management of primary malignant proximal fibular tumors: Functional and clinical outcomes of 23 patients. 原发性腓骨近端恶性肿瘤的手术治疗:23例患者的功能和临床结果。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-04-01 DOI: 10.5606/ehc.2019.62888
İsmail Burak Atalay, Selçuk Yılmaz, İzzet Korkmaz, Mehmet Fatih Ekşioğlu, Bedii Şafak Güngör

Objectives: This study aims to evaluate the clinical characteristics and treatment outcomes of patients with primary malignant tumors located in the proximal fibula.

Patients and methods: This retrospective study included 23 patients (15 males, 8 females; mean age 22.1 years; range, 9 to 63 years) with primary malignant tumors located in the proximal fibula between May 2007 and May 2017. The anamnesis or medical history, physical examination, plain chest radiography, lung computed tomography, direct radiograph, and magnetic resonance imaging of the affected extremity and routine laboratory tests of all patients were evaluated.

Results: Of the patients, 11 were diagnosed with osteosarcoma (47.8%), nine with Ewing's sarcoma (39.1%), two with chondrosarcoma (8.7%), and one was diagnosed with synovial sarcoma (4.3%). Pain and palpable mass were the most common symptoms. Six patients had lung metastases at the time of diagnosis. Of the patients, eight were performed Malawer type 1 resection (34.8%), nine type 2 resection (39.1%), four above knee amputation (17.4%), and two proximal tibia tumor resection prosthesis (8.6%). Mean follow-up duration was 36 months (range, 12 to 119 months). Local recurrence developed in three patients. Mean Musculoskeletal Tumor Society (MSTS) score of all patients was 62.

Conclusion: Surgical treatment of primary malignant tumors of the proximal fibula is problematic. In appropriate indications, Malawer type 1 resection should be the treatment of choice due to lower local recurrence rates and higher MSTS scores.

目的:探讨腓骨近端原发性恶性肿瘤的临床特点及治疗效果。患者和方法:本回顾性研究纳入23例患者(男15例,女8例;平均年龄22.1岁;范围,9至63岁),2007年5月至2017年5月期间原发性恶性肿瘤位于腓骨近端。评估所有患者的记忆或病史、体格检查、胸部平片、肺部计算机断层摄影、直接x线摄影、患肢磁共振成像和常规实验室检查。结果:其中骨肉瘤11例(47.8%),尤文氏肉瘤9例(39.1%),软骨肉瘤2例(8.7%),滑膜肉瘤1例(4.3%)。疼痛和可触及的肿块是最常见的症状。6例患者在诊断时已发生肺转移。其中Malawer 1型切除8例(34.8%),2型切除9例(39.1%),膝上截肢4例(17.4%),胫骨近端肿瘤切除假体2例(8.6%)。平均随访时间36个月(12 ~ 119个月)。3例出现局部复发。所有患者的平均肌肉骨骼肿瘤学会(MSTS)评分为62分。结论:腓骨近端原发性恶性肿瘤的手术治疗存在问题。在适当的适应症下,Malawer 1型切除术应该是治疗的选择,因为局部复发率低,MSTS评分高。
{"title":"Surgical management of primary malignant proximal fibular tumors: Functional and clinical outcomes of 23 patients.","authors":"İsmail Burak Atalay,&nbsp;Selçuk Yılmaz,&nbsp;İzzet Korkmaz,&nbsp;Mehmet Fatih Ekşioğlu,&nbsp;Bedii Şafak Güngör","doi":"10.5606/ehc.2019.62888","DOIUrl":"https://doi.org/10.5606/ehc.2019.62888","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to evaluate the clinical characteristics and treatment outcomes of patients with primary malignant tumors located in the proximal fibula.</p><p><strong>Patients and methods: </strong>This retrospective study included 23 patients (15 males, 8 females; mean age 22.1 years; range, 9 to 63 years) with primary malignant tumors located in the proximal fibula between May 2007 and May 2017. The anamnesis or medical history, physical examination, plain chest radiography, lung computed tomography, direct radiograph, and magnetic resonance imaging of the affected extremity and routine laboratory tests of all patients were evaluated.</p><p><strong>Results: </strong>Of the patients, 11 were diagnosed with osteosarcoma (47.8%), nine with Ewing's sarcoma (39.1%), two with chondrosarcoma (8.7%), and one was diagnosed with synovial sarcoma (4.3%). Pain and palpable mass were the most common symptoms. Six patients had lung metastases at the time of diagnosis. Of the patients, eight were performed Malawer type 1 resection (34.8%), nine type 2 resection (39.1%), four above knee amputation (17.4%), and two proximal tibia tumor resection prosthesis (8.6%). Mean follow-up duration was 36 months (range, 12 to 119 months). Local recurrence developed in three patients. Mean Musculoskeletal Tumor Society (MSTS) score of all patients was 62.</p><p><strong>Conclusion: </strong>Surgical treatment of primary malignant tumors of the proximal fibula is problematic. In appropriate indications, Malawer type 1 resection should be the treatment of choice due to lower local recurrence rates and higher MSTS scores.</p>","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37067899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A new method for the assessment of reduction tension during open reduction in patients with developmental dysplasia of the hip. 一种评估髋关节发育不良患者切开复位时复位张力的新方法。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-04-01 DOI: 10.5606/ehc.2019.61744
Oktay Adanır, Serdar Yüksel, Ozan Beytemur

Objectives: This study aims to describe our standardized method for evaluating the tension of reduction around the hip joint during open reduction in patients with developmental dysplasia of the hip (DDH).

Patients and methods: We retrospectively evaluated 67 pediatric patients (8 males, 59 females; mean age 21.9±11.1 months; range, 9 to 67 months) who were performed open reduction or open reduction with concomitant pelvic and/or femoral osteotomy for DDH at our clinic between January 2009 and March 2014. The amount of distraction between femoral head and acetabulum was measured to evaluate the tension of reduction during surgery. Factors associated with avascular necrosis (AVN) such as age at reduction, presence of concomitant pelvic and/or femoral shortening osteotomy, and severity of dislocation were determined.

Results: Statistically significant association was found between the presence of femoral osteotomy, severity of dislocation, and amount of distraction and AVN. The incidence of AVN was 38.8% (10 grade I, 12 grade II, 3 grade III, and one grade IV AVN). Cut-off value for the amount of distraction to prevent the development of AVN was calculated as 4 mm.

Conclusion: According to our study findings, we advise using our technique for the evaluation of the tension of reduction around the hip joint and performing tension free reduction in the treatment of DDH to minimize the risk of AVN development.

目的:本研究旨在描述我们在髋关节发育不良(DDH)患者切开复位期间评估髋关节周围复位张力的标准化方法。患者和方法:我们回顾性评估了67例儿科患者(男8例,女59例;平均年龄21.9±11.1个月;2009年1月至2014年3月期间在我们诊所接受切开复位或切开复位合并骨盆和/或股骨截骨治疗DDH的患者(9至67个月)。术中测量股骨头与髋臼间牵张量以评估复位张力。与缺血性坏死(AVN)相关的因素,如复位时的年龄,骨盆和/或股骨短截骨术的存在,以及脱位的严重程度被确定。结果:股骨截骨术、脱位严重程度、牵张量和AVN之间存在统计学意义的关联。AVN发生率为38.8% (I级10例,II级12例,III级3例,IV级1例)。结论:根据我们的研究结果,我们建议使用我们的技术来评估髋关节周围的张力复位,并在DDH治疗中进行无张力复位,以尽量减少AVN的发生风险。
{"title":"A new method for the assessment of reduction tension during open reduction in patients with developmental dysplasia of the hip.","authors":"Oktay Adanır,&nbsp;Serdar Yüksel,&nbsp;Ozan Beytemur","doi":"10.5606/ehc.2019.61744","DOIUrl":"https://doi.org/10.5606/ehc.2019.61744","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to describe our standardized method for evaluating the tension of reduction around the hip joint during open reduction in patients with developmental dysplasia of the hip (DDH).</p><p><strong>Patients and methods: </strong>We retrospectively evaluated 67 pediatric patients (8 males, 59 females; mean age 21.9±11.1 months; range, 9 to 67 months) who were performed open reduction or open reduction with concomitant pelvic and/or femoral osteotomy for DDH at our clinic between January 2009 and March 2014. The amount of distraction between femoral head and acetabulum was measured to evaluate the tension of reduction during surgery. Factors associated with avascular necrosis (AVN) such as age at reduction, presence of concomitant pelvic and/or femoral shortening osteotomy, and severity of dislocation were determined.</p><p><strong>Results: </strong>Statistically significant association was found between the presence of femoral osteotomy, severity of dislocation, and amount of distraction and AVN. The incidence of AVN was 38.8% (10 grade I, 12 grade II, 3 grade III, and one grade IV AVN). Cut-off value for the amount of distraction to prevent the development of AVN was calculated as 4 mm.</p><p><strong>Conclusion: </strong>According to our study findings, we advise using our technique for the evaluation of the tension of reduction around the hip joint and performing tension free reduction in the treatment of DDH to minimize the risk of AVN development.</p>","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37067901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery
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