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Icariin promotes early and late stages of fracture healing in rats. 淫羊藿苷促进大鼠骨折早期和晚期愈合。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-10-24 DOI: 10.5606/ehc.2019.66796
Kaan Gürbüz, M. Yerer, P. Gürbüz, M. Halıcı
OBJECTIVESThis study aims to evaluate the effects of locally applied icariin on bone fracture healing in femur fractured rat model.MATERIALS AND METHODSThe study included 64 male Sprague-Dawley rats (mean age 6 months; weighing, 280-490 g) in eight main study groups. Fracture healing process and level were evaluated with radiography, histopathology and dual energy X-ray absorptiometry to investigate the effects of local administration of icariin at varying doses, which is an exogenous osteo-inductive substance. Activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) were measured in the peripheral blood in addition to glutathione (GSH) and myeloperoxidase (MPO) levels to investigate the effects of icariin on the oxidant-antioxidant systems.RESULTSRadiological bone mineral density measurements and histopathological findings revealed that icariin improved all these parameters in the two healing periods tested. Superoxide dismutase activity decreased in association with local icariin application to the fractured side whereas GPx and GSH increased and MPO remained unchanged. Icariin increased the GPx and GSH levels which are responsible from scavenging hydroxyl radical and hydrogen peroxide.CONCLUSIONLocally administered icariin to the fracture accelerated bone healing by reducing the oxidative stress.
目的探讨淫羊藿苷局部应用对大鼠股骨骨折模型骨折愈合的影响。材料与方法雄性Sprague-Dawley大鼠64只,平均年龄6个月;体重280-490克)。采用x线摄影、组织病理学和双能x线吸收仪评估骨折愈合过程和程度,探讨不同剂量淫羊藿苷局部给药对骨折愈合的影响。淫羊藿苷是一种外源性骨诱导物质。通过测定外周血超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GPx)活性、谷胱甘肽过氧化物酶(GSH)和髓过氧化物酶(MPO)水平,探讨淫羊藿苷对氧化-抗氧化系统的影响。结果放射学骨密度测量和组织病理学结果显示淫羊藿苷在两个愈合期改善了所有这些参数。超氧化物歧化酶活性随着局部淫羊藿苷的施用而降低,GPx和GSH升高,而MPO保持不变。淫羊藿苷增加了GPx和GSH的水平,这是清除羟基自由基和过氧化氢的原因。结论局部给药淫羊藿苷可减轻氧化应激,促进骨折愈合。
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引用次数: 9
Treatment of adult isolated ulnar diaphyseal fractures: A comparison of new-generation locked intramedullary nail and plate fixation. 成人孤立性尺骨干骨折的治疗:新一代锁定髓内钉与钢板固定的比较。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-10-24 DOI: 10.5606/ehc.2019.66344
Birkan Kibar, T. Kurtulmuş
OBJECTIVESThis study aims to compare the radiological and functional results of adult patients with isolated ulnar diaphyseal fractures treated with plate and new-generation locked intramedullary nail (IMN).PATIENTS AND METHODSThe study included 57 patients (38 males, 19 females; mean age 39.1 years; range, 18 to 77 years) with isolated ulnar diaphyseal fractures treated with IMN or plate fixation between January 2008 and December 2017. Thirty patients (Plate group) were treated with plate fixation and 27 patients (IMN group) with IMN. Functional results were evaluated according to the Grace-Eversmann evaluation system and the disabilities of the arm, shoulder and hand (DASH) questionnaire.RESULTSThe mean union time was 12.8±1.2 weeks in the IMN group and 13.7±1.4 weeks in the plate group (p=0.092). The mean operation time was significantly shorter in the IMN group (30 minutes) than in the plate group (46 minutes; p<0.001). The mean DASH score was 7.0±4.5 in the IMN group and 7.7±8.6 in the plate group (p=0.766).CONCLUSIONWith similar union rates, functional results, and shorter operation times, locked IMNs are a suitable alternative to plate osteosynthesis in adult isolated ulnar diaphyseal fractures.
目的比较钢板与新一代锁定髓内钉(IMN)治疗成年孤立性尺骨干骨折的影像学和功能效果。患者与方法纳入57例患者(男性38例,女性19例;平均年龄39.1岁;2008年1月至2017年12月期间,18岁至77岁的患者接受了IMN或钢板固定治疗。钢板组30例,内固定组27例。功能结果根据Grace-Eversmann评估系统和手臂、肩膀和手的残疾(DASH)问卷进行评估。结果IMN组和钢板组的平均愈合时间分别为12.8±1.2周和13.7±1.4周(p=0.092)。IMN组平均手术时间(30分钟)明显短于钢板组(46分钟);p < 0.001)。IMN组平均DASH评分为7.0±4.5分,钢板组平均DASH评分为7.7±8.6分(p=0.766)。结论锁定内固定神经网络具有相似的愈合率、功能效果和较短的手术时间,是成人孤立性尺骨干骨折钢板内固定的理想选择。
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引用次数: 4
Biomechanical comparison of a new handy tension band with malleolar screw, bicortical screw and conventional tension band for the fixation of transverse medial malleolar fractures. 新型手持式张力带与外踝螺钉、双皮质螺钉及常规张力带固定内踝横向骨折的生物力学比较。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-10-24 DOI: 10.5606/ehc.2019.66919
T. Kuru, F. Akpinar, Cengiz Işık, Recai Özkılıç, Serdar Ipek, İ. Mutlu, Hasan Kizilay
OBJECTIVESThis study aims to compare the biomechanical features of a new handy tension band with the malleolar screw, bicortical screw and conventional tension band for the fixation of transverse medial malleolar fractures.MATERIALS AND METHODSThis study used 20 Kirschner wires, five cerclage wires, six double-hole U pins, six cortical screws, six malleolar screws, three malleolar clamps and one osteotomy set. A total of 24 tibias of two-year-old cows were obtained and stripped from soft tissue. Each tibia was cut with an electric saw at 15 cm proximal to the tibiotalar joint surface and the proximal tibia sections were discarded. A transverse fracture line was created with an osteotome on the medial malleolus. The tibias were separated into four groups with six tibias in each group. The distal tibia medial malleolar transverse fragments were fixed under guidance of fluoroscopy with the malleolar screw, bicortical screw, conventional tension band and the new handy tension band.RESULTSIn the application of both transverse and axial force, the new handy tension band resisted higher forces in respect of catastrophic damage force being more resistant compared to the bicortical screw, malleolar screw, and conventional tension band. However, in respect of the 2 mm displacement force of the forces applied in the axial and transverse sections, no difference was determined between the handy tension band and the other three implants.CONCLUSIONThe new handy tension band seems to be more successful when biomechanically compared with the other implants.
目的比较一种新型手持式张力带与外踝螺钉、双皮质螺钉及常规张力带固定内踝横向骨折的生物力学特点。材料与方法本研究使用克氏针20枚,环扎针5枚,双孔U销6枚,皮质螺钉6枚,踝骨螺钉6枚,踝骨钳3枚,截骨组1套。取24只2岁奶牛胫骨,并将其从软组织中剥离。每块胫骨在胫骨关节面近端15cm处用电锯切割,胫骨近端部分丢弃。内踝骨切开术形成横向骨折线。胫骨分为4组,每组6块。在透视指导下用踝螺钉、双皮质螺钉、常规张力带和新型手持式张力带固定胫骨远端内踝横向碎片。结果在横向力和轴向力的作用下,新型手持式张力带比双皮质螺钉、外踝螺钉和常规张力带具有更高的抗突变损伤力的能力。然而,在施加在轴向和横截面上的力的2mm位移力方面,手持式张力带与其他三种种植体之间没有差异。结论与其他种植体相比,新型手持式张力带在生物力学方面更成功。
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引用次数: 2
Comparison of early clinical results and re-tear rates of transosseous-equivalent rotator cuff repairs with or without medial knots. 有或无内侧关节结的经骨等效肩袖修复的早期临床结果和再撕裂率的比较。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-10-24 DOI: 10.5606/ehc.2019.70137
T. Gürpınar, B. Polat, Saltuk Buğra Tekin, Ayşe Esin Polat, Engin Çarkçı, Y. Öztürkmen
OBJECTIVESThis study aims to compare the clinical results and repair integrity of two of the commonly used transosseous-equivalent arthroscopic rotator cuff repair techniques, which are the knotless and the medial knotted suture bridge, for patients with full-thickness medium to large-sized rotator cuff tears.PATIENTS AND METHODSThe study included 121 patients (55 males, 66 females; mean age 56.7±7.3 years; range, 39 to 72 years) with cuff tears. In total, 64 shoulders were operated on using the conventional medial knotted suture bridge technique (group A) and 57 shoulders were operated on using the knotless suture bridge technique (group B). The Constant score, visual analog scale (VAS) and active forward flexion angle were assessed preoperatively and after a minimum of 12 months postoperatively. Postoperative rotator cuff integrity was evaluated by magnetic resonance imaging (MRI) after a mean of 19±4.7 months.RESULTSThere were no significant differences between the groups in terms of age, gender, body mass index, and anteroposterior extension of the tear on the sagittal MRIs. Postoperatively, the mean Constant score increased from 32.3±8.5 points to 84±11.6 points in group A and from 31.3±9.3 points to 86.4±8.7 points in group B (p<0.001), while the mean VAS score decreased from 6.0±1.0 to 1.3±1.2 in group A and from 6.4±1.0 to 1.0±0.8 in group B (p<0.001). According to the control MRIs, the re-tear rate was 10.9% (n=7) in group A and 8.8% (n=5) in group B. No statistically significant difference was found in either the clinical scores or re-tear rates between the groups (p>0.05).CONCLUSIONIn comparison to the medial knotted technique, less time-consuming and simpler knotless technique provides similar satisfactory outcomes after a minimum of one year postoperatively.
目的:本研究旨在比较两种常用的经骨等效关节镜下肩袖修复技术,即无结缝合桥和内侧结缝合桥,对全层中~大尺寸肩袖撕裂患者的临床效果和修复完整性。患者与方法121例患者(男性55例,女性66例;平均年龄56.7±7.3岁;范围,39到72岁),袖口撕裂。共有64个肩部采用常规内侧打结缝合桥技术(A组),57个肩部采用无打结缝合桥技术(B组)。在术前和术后至少12个月后评估恒定评分、视觉模拟评分(VAS)和主动前屈角。术后平均19±4.7个月后通过磁共振成像(MRI)评估肩袖完整性。结果两组患者在年龄、性别、体重指数、矢状面mri撕裂前后展度等方面无显著差异。术后平均Constant评分A组由32.3±8.5分提高到84±11.6分,B组由31.3±9.3分提高到86.4±8.7分(p < 0.05)。结论与内侧打结技术相比,无打结技术更简单、耗时更短,术后至少1年即可获得满意的结果。
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引用次数: 8
Comparison of single event multilevel surgery and multiple surgical events in the lower extremities of children with spastic cerebral palsy. 痉挛型脑瘫患儿下肢单事件多节段手术与多事件手术的比较。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-10-24 DOI: 10.5606/ehc.2019.66516
A. Aslan, Sabri Kerem Diril, Demir Demirci, Huseyin Yorgancigil
OBJECTIVESThis study aims to compare patients treated with single event multilevel surgery (SEMS) and multiple surgical events (MSE) for disorders of the lower extremities due to cerebral palsy (CP).PATIENTS AND METHODSThe study included 130 patients (74 males, 56 females; mean age 7.7±4 years; range, 4 to 13 years) who were retrospectively staged preoperatively and at the final follow-up with the Gross Motor Function Classification System (GMFCS). The patients were divided into two groups as group 1 (MSE) and group 2 (SEMS). Gross Motor Function Measure-88 (GMFM-88) was used as evaluation criteria and visual analog scale was used to measure family satisfaction.RESULTSIn the final follow-up, group 2 had better GMFM-88 D and E scores (p=0.037 and p=0.045, respectively). Similarly, family satisfaction was better in group 2 (p=0.047). There was a difference between preoperative and final follow-up GMFCS stages (I, II, III) of all patients (21÷53÷56 and 53÷49÷28; respectively, p<0.001). A total of 3.8 (range, 2-7) operations were performed per child.CONCLUSIONIn this study, SEMS contributed significantly to movement, posture and independence of children with CP compared to MSE. Single event multilevel surgery also increased family satisfaction.
目的本研究旨在比较脑瘫(CP)所致下肢疾病的单事件多节段手术(SEMS)和多事件手术(MSE)治疗。患者与方法本研究纳入130例患者(男性74例,女性56例;平均年龄7.7±4岁;年龄范围4至13岁),术前和最后随访时采用大运动功能分类系统(GMFCS)进行回顾性分期。将患者分为两组:1组(MSE)和2组(SEMS)。以大运动功能量表-88 (GMFM-88)作为评价标准,以视觉模拟量表衡量家庭满意度。结果在末次随访中,2组患者GMFM-88 D、E评分较高(p=0.037、p=0.045)。同样,第二组的家庭满意度更好(p=0.047)。所有患者术前与最终随访GMFCS分期(I、II、III)存在差异(21÷53÷56和53÷49÷28;分别为p < 0.001)。每个儿童总共进行了3.8次手术(范围2-7)。结论在本研究中,与MSE相比,SEMS对CP患儿的运动、姿势和独立性有显著的改善。单事件多节段手术也提高了家庭满意度。
{"title":"Comparison of single event multilevel surgery and multiple surgical events in the lower extremities of children with spastic cerebral palsy.","authors":"A. Aslan, Sabri Kerem Diril, Demir Demirci, Huseyin Yorgancigil","doi":"10.5606/ehc.2019.66516","DOIUrl":"https://doi.org/10.5606/ehc.2019.66516","url":null,"abstract":"OBJECTIVES\u0000This study aims to compare patients treated with single event multilevel surgery (SEMS) and multiple surgical events (MSE) for disorders of the lower extremities due to cerebral palsy (CP).\u0000\u0000\u0000PATIENTS AND METHODS\u0000The study included 130 patients (74 males, 56 females; mean age 7.7±4 years; range, 4 to 13 years) who were retrospectively staged preoperatively and at the final follow-up with the Gross Motor Function Classification System (GMFCS). The patients were divided into two groups as group 1 (MSE) and group 2 (SEMS). Gross Motor Function Measure-88 (GMFM-88) was used as evaluation criteria and visual analog scale was used to measure family satisfaction.\u0000\u0000\u0000RESULTS\u0000In the final follow-up, group 2 had better GMFM-88 D and E scores (p=0.037 and p=0.045, respectively). Similarly, family satisfaction was better in group 2 (p=0.047). There was a difference between preoperative and final follow-up GMFCS stages (I, II, III) of all patients (21÷53÷56 and 53÷49÷28; respectively, p<0.001). A total of 3.8 (range, 2-7) operations were performed per child.\u0000\u0000\u0000CONCLUSION\u0000In this study, SEMS contributed significantly to movement, posture and independence of children with CP compared to MSE. Single event multilevel surgery also increased family satisfaction.","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90719548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Clinical, radiological and patient-reported outcomes in intra-articular calcaneal fractures: Comparison of conservative and surgical treatment. 跟骨关节内骨折的临床、放射学和患者报告结果:保守治疗和手术治疗的比较。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-08-01 DOI: 10.5606/ehc.2019.66447
Ahmet Aslan, Serdar Sargın, Anıl Gülcü, Mehmet Nuri Konya

Objectives: This study aims to compare the radiological, clinical and patient-reported outcomes of patients with intra-articular calcaneus fractures treated conservatively or surgically.

Patients and methods: Fifty-four patients (30 males, 24 females; mean age 41.0 years; range, 18 to 73 years) treated due to calcaneus fracture were included in the study. Twenty-nine patients underwent conservative treatment (group 1) and 25 patients underwent surgical treatment (group 2). The fractures were classified according to Sanders. At the final follow-up, patients' Bohler's angle, The American Orthopedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score and Foot Function Index (FFI) were used to evaluate their radiological, clinical and patient-reported outcomes. Postoperative complications were also noted.

Results: The fracture was at the right foot in 28 patients and the left foot in 26 patients. The mean follow-up duration was 41.1±23.2 months (range, 24 to 126 months). No statistically significant differences were found between the groups in terms of gender, fracture side, mean age, or follow-up duration (p=0.951, p=0.571, p=0.326, and p=0.620, respectively). According to Sanders classification, 18 patients were type 2 and 11 patients were type 3 in group 1, while 11 patients were type 2 and 14 patients were type 3 in group 2. However, there was no statistically significant difference between the groups in terms of the type of the fracture (p=0.184). On the other hand, the outcomes were significantly better for group 2 compared to group 1 in terms of the Bohler's angle, AOFAS and FFI scores (p=0.004, p=0.003 and p=0.006, respectively). In group 1, subtalar arthritis developed in three patients. In group 2, wound healing problems and superficial infection developed in three patients, while subtalar arthritis developed in two patients.

Conclusion: Surgical treatment is more effective in intra-articular calcaneus fractures compared to conservative treatment according to clinical, radiological and patient-reported outcomes. In addition, wound problems should be considered in surgical management.

目的:本研究旨在比较跟骨关节内骨折患者的放射学、临床和患者报告的结果。患者与方法:54例患者(男30例,女24例;平均年龄41.0岁;研究对象为18至73岁的跟骨骨折患者。保守治疗29例(第一组),手术治疗25例(第二组)。骨折按Sanders分类。在最后的随访中,使用患者的Bohler角、美国骨科足踝学会(AOFAS)踝关节-后足评分和足功能指数(FFI)来评估他们的放射学、临床和患者报告的结果。术后并发症也有记录。结果:右脚骨折28例,左脚骨折26例。平均随访时间为41.1±23.2个月(24 ~ 126个月)。两组患者性别、骨折侧、平均年龄、随访时间差异无统计学意义(p=0.951、p=0.571、p=0.326、p=0.620)。根据Sanders分类,1组2型18例,3型11例;2组2型11例,3型14例。但两组间骨折类型差异无统计学意义(p=0.184)。另一方面,在Bohler角、AOFAS和FFI评分方面,2组的结果明显优于1组(p=0.004、p=0.003和p=0.006)。在第一组中,3名患者出现距下关节炎。在第二组中,3例患者出现伤口愈合问题和浅表感染,2例患者出现距下关节炎。结论:从临床、影像学和患者报告的结果来看,手术治疗跟骨关节内骨折比保守治疗更有效。此外,伤口问题应考虑到手术处理。
{"title":"Clinical, radiological and patient-reported outcomes in intra-articular calcaneal fractures: Comparison of conservative and surgical treatment.","authors":"Ahmet Aslan,&nbsp;Serdar Sargın,&nbsp;Anıl Gülcü,&nbsp;Mehmet Nuri Konya","doi":"10.5606/ehc.2019.66447","DOIUrl":"https://doi.org/10.5606/ehc.2019.66447","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare the radiological, clinical and patient-reported outcomes of patients with intra-articular calcaneus fractures treated conservatively or surgically.</p><p><strong>Patients and methods: </strong>Fifty-four patients (30 males, 24 females; mean age 41.0 years; range, 18 to 73 years) treated due to calcaneus fracture were included in the study. Twenty-nine patients underwent conservative treatment (group 1) and 25 patients underwent surgical treatment (group 2). The fractures were classified according to Sanders. At the final follow-up, patients' Bohler's angle, The American Orthopedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score and Foot Function Index (FFI) were used to evaluate their radiological, clinical and patient-reported outcomes. Postoperative complications were also noted.</p><p><strong>Results: </strong>The fracture was at the right foot in 28 patients and the left foot in 26 patients. The mean follow-up duration was 41.1±23.2 months (range, 24 to 126 months). No statistically significant differences were found between the groups in terms of gender, fracture side, mean age, or follow-up duration (p=0.951, p=0.571, p=0.326, and p=0.620, respectively). According to Sanders classification, 18 patients were type 2 and 11 patients were type 3 in group 1, while 11 patients were type 2 and 14 patients were type 3 in group 2. However, there was no statistically significant difference between the groups in terms of the type of the fracture (p=0.184). On the other hand, the outcomes were significantly better for group 2 compared to group 1 in terms of the Bohler's angle, AOFAS and FFI scores (p=0.004, p=0.003 and p=0.006, respectively). In group 1, subtalar arthritis developed in three patients. In group 2, wound healing problems and superficial infection developed in three patients, while subtalar arthritis developed in two patients.</p><p><strong>Conclusion: </strong>Surgical treatment is more effective in intra-articular calcaneus fractures compared to conservative treatment according to clinical, radiological and patient-reported outcomes. In addition, wound problems should be considered in surgical management.</p>","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37133825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Comparison of the impact factors of subscription access and open access orthopedics and sports medicine journals in the SCImago database. SCImago数据库骨科与运动医学期刊订阅获取与开放获取影响因子比较
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-08-01 DOI: 10.5606/ehc.2019.64729
Barış Polat, Ramadan Özmanevra, Pınar Tunçbilek Özmanevra, Kadir Çağdaş Kazıkdaş

Objectives: This study aims to compare the annual impact factors (IFs) for the period 1999-2017 and the tri-annual IFs in 2011, 2014 and 2017 of the subscription access (SA) and open access (OA) journals published in the field of orthopedics, traumatology and sports medicine according to the SCImago Journal Rank (SJR).

Material and methods: All data for this study were obtained from the SCImago Journal & Country Rank database. We compared the change in the mean annual IFs of 197 SA journals with 52 OA journals in the field of orthopedics and sports medicine for the period between 1999 and 2017. In addition, we determined and compared the changes in the mean tri-annual IFs of these journals in 2011, 2014 and 2017. The mean publication fee values of the OA journals as well as the correlation between the three-year IFs of the year 2017 and the publication fee values were evaluated.

Results: From 1999 to 2017, the mean IF of SA journals increased 0.47-fold to 0.69, while the mean IF of the OA journals increased 0.85-fold to 0.63. Significant positive correlation was observed between the tri-annual IF and publication fee of OA journals in 2017 (r=0.458, p=0.001).

Conclusion: We can predict that the mean IFs of OA journals in the field of orthopedics and sports medicine will reach the mean IFs of SA journals after several years. Choosing OA journals becomes advantageous when the desire for a higher number of citations is the most important factor.

目的:比较SCImago期刊排名(SJR)中骨科、创伤学和运动医学领域的订阅获取(SA)和开放获取(OA)期刊1999-2017年的年度影响因子(IFs)和2011年、2014年和2017年的三年影响因子(IFs)。材料和方法:本研究的所有数据均来自SCImago Journal & Country Rank数据库。我们比较了1999年至2017年期间骨科和运动医学领域的197种SA期刊和52种OA期刊的平均年度影响因子的变化。此外,我们确定并比较了这些期刊在2011年、2014年和2017年的平均三年期if的变化。评估开放获取期刊的平均出版费用价值以及2017年3年if与出版费用价值的相关性。结果:1999 - 2017年,SA期刊的平均影响因子增加了0.47倍,达到0.69;OA期刊的平均影响因子增加了0.85倍,达到0.63。2017年OA期刊三年期IF与出版费用呈显著正相关(r=0.458, p=0.001)。结论:我们可以预测,骨科和运动医学领域OA期刊的平均IFs将在几年后达到SA期刊的平均IFs。当对更高引用次数的渴望是最重要的因素时,选择OA期刊就变得有利。
{"title":"Comparison of the impact factors of subscription access and open access orthopedics and sports medicine journals in the SCImago database.","authors":"Barış Polat,&nbsp;Ramadan Özmanevra,&nbsp;Pınar Tunçbilek Özmanevra,&nbsp;Kadir Çağdaş Kazıkdaş","doi":"10.5606/ehc.2019.64729","DOIUrl":"https://doi.org/10.5606/ehc.2019.64729","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare the annual impact factors (IFs) for the period 1999-2017 and the tri-annual IFs in 2011, 2014 and 2017 of the subscription access (SA) and open access (OA) journals published in the field of orthopedics, traumatology and sports medicine according to the SCImago Journal Rank (SJR).</p><p><strong>Material and methods: </strong>All data for this study were obtained from the SCImago Journal & Country Rank database. We compared the change in the mean annual IFs of 197 SA journals with 52 OA journals in the field of orthopedics and sports medicine for the period between 1999 and 2017. In addition, we determined and compared the changes in the mean tri-annual IFs of these journals in 2011, 2014 and 2017. The mean publication fee values of the OA journals as well as the correlation between the three-year IFs of the year 2017 and the publication fee values were evaluated.</p><p><strong>Results: </strong>From 1999 to 2017, the mean IF of SA journals increased 0.47-fold to 0.69, while the mean IF of the OA journals increased 0.85-fold to 0.63. Significant positive correlation was observed between the tri-annual IF and publication fee of OA journals in 2017 (r=0.458, p=0.001).</p><p><strong>Conclusion: </strong>We can predict that the mean IFs of OA journals in the field of orthopedics and sports medicine will reach the mean IFs of SA journals after several years. Choosing OA journals becomes advantageous when the desire for a higher number of citations is the most important factor.</p>","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37147355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Comparison of arthroscopic microfracture and cell-free scaffold implantation techniques in the treatment of talar osteochondral lesions. 关节镜下微骨折与无细胞支架植入治疗距骨软骨病变的比较。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-08-01 DOI: 10.5606/ehc.2019.64401
Toygun Kağan Eren, Muhammet Baybars Ataoğlu, Ali Eren, Dilan Ece Geylan, Ali Yusuf Öner, Ulunay Kanatlı

Objectives: This study aims to compare two single-step arthroscopic techniques, microfracture and cell-free scaffold implantation, in the treatment of talar osteochondral lesions (OCLs) clinically and radiologically.

Patients and methods: This retrospective study included 62 patients (35 males, 27 females; mean age 41±13 years; range, 15 to 65 years) diagnosed with talar OCLs between March 2007 and January 2015. Patients who were followed-up with a minimum of 24 months with lesions larger than 1 cm2 were included. Pre- and postoperative clinical evaluations were performed according to the American Orthopedic Foot and Ankle Society (AOFAS) ankle-hindfoot scale and radiological evaluations according to the magnetic resonance observation of cartilage repair tissue (MOCART) scale.

Results: Patients were divided into microfracture (n=22) and scaffold (n=40) groups. The mean follow-up duration was 36.1±14.9 months. The mean preoperative AOFAS score increased from 60.6±13.9 to 82.1±11.8 in the microfracture group (p<0.001) and from 53.8±13.6 to 89.4±9.9 in the scaffold group (p<0.001). The scaffold group had superior results than the microfracture group clinically (p=0.011). Clinical results were superior in younger patients (<45 years) (p=0.018), male patients (p=0.020), and traumatic lesions (p=0.014). There was no significant difference between the two techniques according to the total MOCART scores (p=0.199). However, the scaffold technique was more successful in terms of lesion border and effusion subgoups of MOCART scale.

Conclusion: Both single-step arthroscopic techniques are effective and safe in the treatment of talar OCLs. The scaffold technique showed superior clinical results than the microfracture technique in short-term follow-up. Age, trauma history and gender significantly affected the treatment outcomes. The scaffold technique can be considered as a safe and good alternative particularly in the treatment of large lesions.

目的:本研究旨在比较两种单步关节镜技术,微骨折和无细胞支架植入治疗距骨软骨病变(ocl)的临床和影像学效果。患者和方法:本回顾性研究纳入62例患者(男35例,女27例;平均年龄41±13岁;在2007年3月至2015年1月期间,年龄在15岁至65岁之间。随访至少24个月且病灶大于1cm2的患者纳入研究。术前和术后临床评价采用美国骨科足踝学会(AOFAS)踝后量表,影像学评价采用软骨修复组织磁共振观察(MOCART)量表。结果:患者分为微骨折组(22例)和支架组(40例)。平均随访36.1±14.9个月。微骨折组术前平均AOFAS评分由60.6±13.9上升至82.1±11.8。结论:单步关节镜技术治疗距骨骨鳞状细胞是安全有效的。短期随访中支架技术临床效果优于微骨折技术。年龄、创伤史和性别显著影响治疗结果。支架技术可以被认为是一种安全而良好的替代方法,特别是在治疗大病变方面。
{"title":"Comparison of arthroscopic microfracture and cell-free scaffold implantation techniques in the treatment of talar osteochondral lesions.","authors":"Toygun Kağan Eren,&nbsp;Muhammet Baybars Ataoğlu,&nbsp;Ali Eren,&nbsp;Dilan Ece Geylan,&nbsp;Ali Yusuf Öner,&nbsp;Ulunay Kanatlı","doi":"10.5606/ehc.2019.64401","DOIUrl":"https://doi.org/10.5606/ehc.2019.64401","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare two single-step arthroscopic techniques, microfracture and cell-free scaffold implantation, in the treatment of talar osteochondral lesions (OCLs) clinically and radiologically.</p><p><strong>Patients and methods: </strong>This retrospective study included 62 patients (35 males, 27 females; mean age 41±13 years; range, 15 to 65 years) diagnosed with talar OCLs between March 2007 and January 2015. Patients who were followed-up with a minimum of 24 months with lesions larger than 1 cm2 were included. Pre- and postoperative clinical evaluations were performed according to the American Orthopedic Foot and Ankle Society (AOFAS) ankle-hindfoot scale and radiological evaluations according to the magnetic resonance observation of cartilage repair tissue (MOCART) scale.</p><p><strong>Results: </strong>Patients were divided into microfracture (n=22) and scaffold (n=40) groups. The mean follow-up duration was 36.1±14.9 months. The mean preoperative AOFAS score increased from 60.6±13.9 to 82.1±11.8 in the microfracture group (p<0.001) and from 53.8±13.6 to 89.4±9.9 in the scaffold group (p<0.001). The scaffold group had superior results than the microfracture group clinically (p=0.011). Clinical results were superior in younger patients (<45 years) (p=0.018), male patients (p=0.020), and traumatic lesions (p=0.014). There was no significant difference between the two techniques according to the total MOCART scores (p=0.199). However, the scaffold technique was more successful in terms of lesion border and effusion subgoups of MOCART scale.</p><p><strong>Conclusion: </strong>Both single-step arthroscopic techniques are effective and safe in the treatment of talar OCLs. The scaffold technique showed superior clinical results than the microfracture technique in short-term follow-up. Age, trauma history and gender significantly affected the treatment outcomes. The scaffold technique can be considered as a safe and good alternative particularly in the treatment of large lesions.</p>","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37133818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
The role of biomarkers in osteoarthritis and osteoporosis for early diagnosis and monitoring prognosis. 生物标志物在骨关节炎和骨质疏松症早期诊断和监测预后中的作用。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-08-01 DOI: 10.5606/ehc.2019.004
O Şahap Atik, Erdem Aras Sezgin, H Emre Tepedelenlioğlu
There are a number of promising candidates for biomarkers such as urinary C-terminal telopeptide of type II collagen and serum cartilage oligomeric matrix protein, while none is sufficiently discriminating for diagnosis or prediction of prognosis in patients or for use as a surrogate outcome in clinical trials.[4] However, the combination of specific markers seems to improve the prediction of disease progression at the individual level.[5]
{"title":"The role of biomarkers in osteoarthritis and osteoporosis for early diagnosis and monitoring prognosis.","authors":"O Şahap Atik,&nbsp;Erdem Aras Sezgin,&nbsp;H Emre Tepedelenlioğlu","doi":"10.5606/ehc.2019.004","DOIUrl":"https://doi.org/10.5606/ehc.2019.004","url":null,"abstract":"There are a number of promising candidates for biomarkers such as urinary C-terminal telopeptide of type II collagen and serum cartilage oligomeric matrix protein, while none is sufficiently discriminating for diagnosis or prediction of prognosis in patients or for use as a surrogate outcome in clinical trials.[4] However, the combination of specific markers seems to improve the prediction of disease progression at the individual level.[5]","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37147357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Fit assessment of two different anatomically contoured distal femur plate sets on cadaveric bones. 两种不同解剖形状股骨远端钢板在尸体骨上的贴合评估。
IF 1.6 4区 医学 Q2 Medicine Pub Date : 2019-08-01 DOI: 10.5606/ehc.2019.64940
Ali Utkan, Volkan İğdir, Aydın Arslan, Tülin Şen Esmer, Bülent Özkurt

Objectives: This study aims to investigate the fitness of two anatomic distal femoral plates with cadaveric femurs and to show whether current plates optimally match each femur.

Materials and methods: Two different sets of plates with five, seven and nine shaft holes were applicated on 62 cadaveric femurs. Ball clay was molded onto the entire inner surfaces of the plates and then the plates were fixed to the bones using two self-locking nylon cable zip ties. The volume of ball clay sandwiched in between the plate and bone was calculated and used as a quantitative fit parameter. Data of each plate were analyzed separately.

Results: Using Double Medical Technology IncorporatedTM plates, the mean plate to bone volumes were calculated as 8.4 mL (range, 5-14 mL), 10.0 mL (range, 6-17 mL), and 13.1 mL (range, 7-25 mL) in five, seven and nine-hole plates, respectively. Using Zimmer Biomet IncorporatedTM plates, the mean volumes were 10.5 mL (range, 6-21 mL), 12.7 mL (range, 7-22 mL) and 16.3 mL (range, 8-30 mL) in five, seven and nine-hole plates, respectively. Within each group, the measurements were significantly correlated positively with femoral length.

Conclusion: Optimal fit may not be achieved in each femur using current distal femoral plate implant sets. Thus additional sizes of plates should be supplied in the implant sets.

目的:本研究旨在探讨两个解剖股骨远端钢板与尸体股骨的适应性,并显示当前钢板是否与每根股骨最佳匹配。材料与方法:将5孔、7孔和9孔两组不同的钢板应用于62具尸体股骨。球粘土被模压在钢板的整个内表面上,然后用两个自锁尼龙电缆拉链将钢板固定在骨头上。计算了夹在板与骨之间的球泥体积,并将其作为定量拟合参数。各板数据分别进行分析。结果:采用Double Medical Technology公司的tm板,计算出五孔、七孔和九孔板的平均板骨体积分别为8.4 mL(范围5-14 mL)、10.0 mL(范围6-17 mL)和13.1 mL(范围7-25 mL)。使用Zimmer Biomet incorporated™板,五孔、七孔和九孔板的平均体积分别为10.5 mL(范围6-21 mL)、12.7 mL(范围7-22 mL)和16.3 mL(范围8-30 mL)。在每一组中,测量值与股骨长度显著正相关。结论:目前使用的股骨远端钢板植入装置可能无法达到最佳配合。因此,在植入装置中应提供额外尺寸的钢板。
{"title":"Fit assessment of two different anatomically contoured distal femur plate sets on cadaveric bones.","authors":"Ali Utkan,&nbsp;Volkan İğdir,&nbsp;Aydın Arslan,&nbsp;Tülin Şen Esmer,&nbsp;Bülent Özkurt","doi":"10.5606/ehc.2019.64940","DOIUrl":"https://doi.org/10.5606/ehc.2019.64940","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate the fitness of two anatomic distal femoral plates with cadaveric femurs and to show whether current plates optimally match each femur.</p><p><strong>Materials and methods: </strong>Two different sets of plates with five, seven and nine shaft holes were applicated on 62 cadaveric femurs. Ball clay was molded onto the entire inner surfaces of the plates and then the plates were fixed to the bones using two self-locking nylon cable zip ties. The volume of ball clay sandwiched in between the plate and bone was calculated and used as a quantitative fit parameter. Data of each plate were analyzed separately.</p><p><strong>Results: </strong>Using Double Medical Technology IncorporatedTM plates, the mean plate to bone volumes were calculated as 8.4 mL (range, 5-14 mL), 10.0 mL (range, 6-17 mL), and 13.1 mL (range, 7-25 mL) in five, seven and nine-hole plates, respectively. Using Zimmer Biomet IncorporatedTM plates, the mean volumes were 10.5 mL (range, 6-21 mL), 12.7 mL (range, 7-22 mL) and 16.3 mL (range, 8-30 mL) in five, seven and nine-hole plates, respectively. Within each group, the measurements were significantly correlated positively with femoral length.</p><p><strong>Conclusion: </strong>Optimal fit may not be achieved in each femur using current distal femoral plate implant sets. Thus additional sizes of plates should be supplied in the implant sets.</p>","PeriodicalId":50551,"journal":{"name":"Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37133824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Eklem Hastaliklari Ve Cerrahisi-Joint Diseases and Related Surgery
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