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Size and Function of the Right Atrium in Healthy Children by Three-Dimensional Echocardiography 通过三维超声心动图观察健康儿童右心房的大小和功能
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-10 DOI: 10.1111/echo.15929
Brendan Haughian, Pei-Ni Jone, Lisa Le, Nee Scze Khoo, Timothy Colen, Zoe Vetten, Luke Eckersley

Purpose

Right atrial volume (RAV) and function have proven prognostic value in the assessment of cardiac disease and may be more accurately assessed using three-dimensional echocardiography (3DE). Normal 3DE reference values for the right atrial (RA) volume and function in healthy children have not yet been published. Furthermore, current methods of indexing cardiac measurements to body surface area (BSA) alone may be insufficient. We aimed to develop reference values for 3DE-derived RAV and function in the pediatric population, to provide a comparison of regression methods using BSA, height, weight, and sex, and to compare 3DE values to two-dimensional echocardiography (2DE) derived volumes.

Methods

We retrospectively analyzed 187 3DE datasets acquired for a multi-center study on healthy children at two international centers. 3DE volumes were measured with vendor-agnostic software (Tomtec), and 2DE endo-diastolic volume (EDV) using the area-length single-plane approach. Regression curve-fitting of height (Ht), weight (Wt), BSA, and sex were explored to optimize Pearson coefficient and homoscedasticity.

Results

The relationship of 3DE RAVs to BSA alone was heteroscedastic, with a residual positive relationship on indexing (R2 = 0.2506). Optimal regression of Ln (Volume) = b0 + x*Ln (Ht) + y*Ln (Wt) + z*Sex was homoscedastic. Total RA emptying fraction (EF) did not vary across age or sex, however active and passive emptying was best fit by a spline curve with a knot at approximately BSA = 1 m2. Strong agreement with 2DE-derived EDV was present (r2 = 0.83).

Conclusion

We provide reference values for RA size and function in the pediatric population and provide a comparison of methods for indexing these values.

目的 右心房容积(RAV)和功能在心脏疾病的评估中已被证明具有预后价值,使用三维超声心动图(3DE)可对其进行更准确的评估。目前尚未公布健康儿童右心房容积和功能的正常三维超声心动图参考值。此外,目前仅将心脏测量值与体表面积(BSA)挂钩的方法可能不够充分。我们的目的是为三维超声心动图(3DE)得出的儿童心房体积和功能制定参考值,比较使用体表面积(BSA)、身高、体重和性别的回归方法,并将三维超声心动图值与二维超声心动图(2DE)得出的心房体积进行比较。 方法 我们回顾性分析了在两个国际中心进行的一项多中心研究中获得的 187 个三维超声心动图数据集,这些数据集针对的是健康儿童。三维超声心动图的容积是用供应商诊断软件(Tomtec)测量的,二维超声心动图的舒张末期容积(EDV)是用面积-长度单平面方法测量的。探讨了身高(Ht)、体重(Wt)、BSA 和性别的回归曲线拟合,以优化皮尔逊系数和同方差性。 结果 仅 3DE RAV 与 BSA 的关系是异方差的,与指数化的残余正相关(R2 = 0.2506)。Ln (Volume) = b0 + x*Ln (Ht) + y*Ln (Wt) + z*Sex 的最佳回归是同方差的。总 RA 排空分数(EF)不随年龄或性别而变化,但主动和被动排空的最佳拟合曲线是以大约 BSA = 1 m2 为节点的样条曲线。与 2DE 导出的 EDV 非常吻合(r2 = 0.83)。 结论 我们提供了小儿 RA 大小和功能的参考值,并对这些值的指数化方法进行了比较。
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引用次数: 0
Complete Transposition of the Great Arteries: 5-Year Experience From a Single Center 大动脉完全移位:一个中心的五年经验
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-09 DOI: 10.1111/echo.15940
Oung Savly MD, FASE, FAPSC, Sujith S. Pereira FRCPCH, FESC, PhD, Ponn Ladin MD

Complete transposition of the great arteries (TGA) is the most common cause of cyanosis in the first week of life. Prenatal diagnosis helps with counseling, planning delivery, and postnatal management for resource-rich health services. In a resource-limited setting, postnatal diagnosis is the norm. This work examines cases of complete TGA in one center in Cambodia without prenatal testing. Twenty-four cases were studied over 5 years. Complex TGA was frequently seen. The majority had normal coronary anatomy and arterial switch operation (ASO) was performed in most cases with a favorable outcome.

完全性大动脉转位(TGA)是导致婴儿出生后第一周出现紫绀的最常见原因。对于资源丰富的医疗服务机构而言,产前诊断有助于咨询、计划分娩和产后管理。在资源有限的环境中,通常采用产后诊断。本研究对柬埔寨一家中心在未进行产前检测的情况下发生的完全性 TGA 病例进行了研究。在 5 年时间里研究了 24 个病例。复杂的TGA经常出现。大多数病例的冠状动脉解剖结构正常,并进行了动脉转换手术(ASO),结果良好。
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引用次数: 0
Artificial Intelligence Echocardiography in Resource-Limited Regions: Applications and Challenges 资源有限地区的人工智能超声心动图:应用与挑战。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-05 DOI: 10.1111/echo.15939
Izhan Hamza, Patricia A. Pellikka, Amer Abdulla, Masood Ahmad

Artificial intelligence (AI) is revolutionizing cardiac imaging, including echocardiography. However, AI has scarce penetration in resource-limited regions. The implementation of AI-aided echocardiography (AIE) poses unique challenges and opportunities in resource-limited areas. Some obvious advantages of AIE include aiding image acquisition, interpretation, and triaging patients based on severity. The challenges AIE faces in resource-limited regions include a lack of data accessibility for model development, physician apprehension, and an outdated regulatory framework. Based on our early experience with AI, we believe AIE in resource-limited regions will enhance health equity, improve access to the technology, and lead to cost savings. However, significant efforts are needed to realize these objectives.

人工智能(AI)正在彻底改变包括超声心动图在内的心脏成像技术。然而,人工智能在资源有限的地区普及率很低。在资源有限的地区,人工智能辅助超声心动图(AIE)的实施带来了独特的挑战和机遇。人工智能辅助超声心动图的一些明显优势包括辅助图像采集、解读和根据严重程度分流患者。人工智能心动图在资源有限地区面临的挑战包括:缺乏用于模型开发的数据、医生的疑虑和过时的监管框架。根据我们在人工智能方面的早期经验,我们相信在资源有限的地区开展人工智能医疗将提高医疗公平性,改善技术的可及性,并节约成本。然而,要实现这些目标还需要付出巨大的努力。
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引用次数: 0
Noninvasive Left Ventricular Pressure-Strain Loop for Quantitative Assessment of Early Left Ventricular Systolic Dysfunction in Patients With Chronic Kidney Disease 用于定量评估慢性肾病患者早期左心室收缩功能障碍的无创左心室压力-应变环路。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-05 DOI: 10.1111/echo.15941
Qin Wang, Jin-Ping Wang, Yan Li, Jie Zhang, Rui Wang, Hai-Yun Xu

Background

Patients with chronic kidney disease (CKD) possess a pronounced risk for cardiovascular events. A noninvasive left ventricular pressure-strain loop (LV-PSL) has recently been introduced to detect subtler changes in cardiac function. This study aims to investigate the value of LV-PSL for quantitative assessment of myocardial work (MW) in patients with CKD.

Methods

Seventy-five patients with CKD were enrolled retrospectively (37 patients with CKD Stages 2–3, and 38 patients with CKD Stages 4–5), and 35 healthy volunteers were included as controls. All subjects underwent transthoracic echocardiography. LV-PSL analysis was performed to estimate LV MW and efficiency. Global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE) were obtained by echocardiography, and the differences among the groups were compared.

Results

There was a significant increase in GWW and reduction in GWE in patients with CKD compared to normal controls (p < 0.05). No significant difference in GWI and GCW was observed among the three groups. Multiple linear regression revealed that increased GWW was significantly associated with age, serum creatinine, and systolic pressure, and decreased GWE was associated with age, serum creatinine, and GLS.

Conclusion

LV-PSL can be used for noninvasive quantitative assessment of MW in patients with CKD, providing a new sensitive approach for the clinical assessment of myocardial function.

背景:慢性肾脏病(CKD)患者有明显的心血管事件风险。最近推出的无创左心室压力应变环(LV-PSL)可检测心脏功能的细微变化。本研究旨在探讨 LV-PSL 在定量评估慢性肾脏病患者心肌功(MW)方面的价值:75名慢性肾脏病患者(37名慢性肾脏病2-3期患者和38名慢性肾脏病4-5期患者)和35名健康志愿者作为对照。所有受试者均接受了经胸超声心动图检查。进行左心室-PSL分析以估算左心室的重量和效率。通过超声心动图获得全局工作指数(GWI)、全局建设性工作(GCW)、全局浪费工作(GWW)和全局工作效率(GWE),并比较各组间的差异:结果:与正常对照组相比,慢性肾脏病患者的 GWW 明显增加,GWE 明显降低(P < 0.05)。三组患者的 GWI 和 GCW 无明显差异。多元线性回归显示,GWW的增加与年龄、血清肌酐和收缩压显著相关,而GWE的减少与年龄、血清肌酐和GLS相关:结论:LV-PSL 可用于无创定量评估慢性肾脏病患者的 MW,为临床评估心肌功能提供了一种新的敏感方法。
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引用次数: 0
Benefit of Interventional Septal Reduction for Hypertrophic Cardiomyopathy: Looking for a Needle in a Haystack? 肥厚型心肌病介入性房间隔缩短术的益处:大海捞针?
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-05 DOI: 10.1111/echo.15952
Olivier Piot, Olivier Paziaud, Julien Dreyfus
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引用次数: 0
Cardiovascular Magnetic Resonance Imaging of Takotsubo Syndrome: Evolving Diagnostic and Prognostic Perspectives 塔克次氏综合征的心血管磁共振成像:不断发展的诊断和预后观点。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-05 DOI: 10.1111/echo.15949
Riccardo Cau, Salvatore Masala, Lorenzo Manelli, Michele Porcu, Mariano Scaglione, Tommaso D'Angelo, Rodrigo Salgado, Luca Saba

Takotsubo syndrome (TS) is a temporary form of left ventricular (LV) dysfunction characterized by a distinct pattern of LV impairment, often triggered by a physical or emotional stressful event. Historically, TS was considered a benign condition due to its prompt restoration of myocardial function and generally excellent outcomes. However, recent studies have shown that complications similar to those seen after myocardial infarction can occur, necessitating careful monitoring of these patients. Among noninvasive imaging techniques, cardiovascular magnetic resonance (CMR) is becoming increasingly important in evaluating patients with TS. CMR offers a unique ability to noninvasively assess myocardial tissue characteristics, allowing for detecting the typical features of TS, such as specific wall motion abnormalities and myocardial edema. Beyond its well-established diagnostic utility in the clinical management of TS, CMR has also proven valuable in prognosis and risk stratification for these patients. Advances in CMR, including myocardial strain and parametric mapping have expanded its role in the diagnosis, prognosis, and follow-up of these patients. This review aims to provide a comprehensive overview of the potential applications of CMR in the diagnostic and prognostic evaluation of TS patients. It explores the emerging use of novel CMR imaging biomarkers that may enhance diagnosis, improve prognostic accuracy, and contribute to the overall management of these patients.

高突波综合征(Takotsubo syndrome,TS)是一种暂时性左心室(LV)功能障碍,其特征是一种明显的左心室功能损害模式,通常由身体或情绪上的应激事件引发。从历史上看,TS 被认为是一种良性病症,因为它能迅速恢复心肌功能,而且一般都能取得很好的疗效。然而,最近的研究表明,可能会出现类似于心肌梗塞后的并发症,因此有必要对这些患者进行仔细监测。在非侵入性成像技术中,心血管磁共振(CMR)在评估 TS 患者方面的重要性与日俱增。CMR 具有无创评估心肌组织特征的独特能力,可检测出 TS 的典型特征,如特定的室壁运动异常和心肌水肿。除了在 TS 的临床治疗中具有公认的诊断作用外,CMR 还被证明在这些患者的预后和风险分层方面具有重要价值。包括心肌应变和参数图在内的 CMR 技术的进步扩大了其在这些患者的诊断、预后和随访中的作用。本综述旨在全面概述 CMR 在 TS 患者诊断和预后评估中的潜在应用。它探讨了新型 CMR 成像生物标记物的新兴应用,这些标记物可增强诊断、提高预后准确性并有助于这些患者的整体管理。
{"title":"Cardiovascular Magnetic Resonance Imaging of Takotsubo Syndrome: Evolving Diagnostic and Prognostic Perspectives","authors":"Riccardo Cau,&nbsp;Salvatore Masala,&nbsp;Lorenzo Manelli,&nbsp;Michele Porcu,&nbsp;Mariano Scaglione,&nbsp;Tommaso D'Angelo,&nbsp;Rodrigo Salgado,&nbsp;Luca Saba","doi":"10.1111/echo.15949","DOIUrl":"10.1111/echo.15949","url":null,"abstract":"<div>\u0000 \u0000 <p>Takotsubo syndrome (TS) is a temporary form of left ventricular (LV) dysfunction characterized by a distinct pattern of LV impairment, often triggered by a physical or emotional stressful event. Historically, TS was considered a benign condition due to its prompt restoration of myocardial function and generally excellent outcomes. However, recent studies have shown that complications similar to those seen after myocardial infarction can occur, necessitating careful monitoring of these patients. Among noninvasive imaging techniques, cardiovascular magnetic resonance (CMR) is becoming increasingly important in evaluating patients with TS. CMR offers a unique ability to noninvasively assess myocardial tissue characteristics, allowing for detecting the typical features of TS, such as specific wall motion abnormalities and myocardial edema. Beyond its well-established diagnostic utility in the clinical management of TS, CMR has also proven valuable in prognosis and risk stratification for these patients. Advances in CMR, including myocardial strain and parametric mapping have expanded its role in the diagnosis, prognosis, and follow-up of these patients. This review aims to provide a comprehensive overview of the potential applications of CMR in the diagnostic and prognostic evaluation of TS patients. It explores the emerging use of novel CMR imaging biomarkers that may enhance diagnosis, improve prognostic accuracy, and contribute to the overall management of these patients.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 10","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tetralogy of Fallot With Absent Pulmonary Valve Syndrome: The Experience of a Tertiary Care Center in a Developing Country 法洛氏四联症伴无肺动脉瓣综合征:发展中国家三级医疗中心的经验。
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-05 DOI: 10.1111/echo.15942
Aziz Farhat, Sujud Charanek, Rana Zareef, Issam El-Rassi, Fadi Bitar, Mariam Arabi

Background

Tetralogy of Fallot with an absent pulmonary valve is a very rare variant of tetralogy. It is characterized by absent valve tissue, severe pulmonary regurgitation, and secondary aneurysmal dilatation of the pulmonary arteries.

Aim

In this study, we aim to investigate the clinical presentations, management strategies, and outcomes of patients with tetralogy of Fallot and absent pulmonary valve.

Methodology

We retrospectively reviewed the charts of all patients who presented to the American University of Beirut Medical Center between January 2010 and December 2020 and who were diagnosed with this anomaly.

Results

A total of 300 cases of tetralogy of Fallot were identified, of which 18 patients had absent pulmonary valves. They were followed up for an average of 8.2 years. Prenatal diagnoses were made in four patients, while 13 patients were identified in the neonatal period, with an average age of 4.5 days. Genetic testing confirmed DiGeorge syndrome in one patient. Five patients underwent surgical intervention in the neonatal period, while the remaining patients were operated on during their early childhood. While overall there were no surgical mortalities nor any need for reinterventions, a variety of morbidities were encountered.

Conclusion

This study provides an overview of this rare anomaly and its management in a developing country.

背景:法洛氏四联症伴肺动脉瓣缺失是一种非常罕见的四联症变异型。目的:本研究旨在探讨法洛四联症伴肺动脉瓣缺失患者的临床表现、治疗策略和预后:我们回顾性地查看了 2010 年 1 月至 2020 年 12 月期间在贝鲁特美国大学医疗中心就诊并被确诊为这种异常的所有患者的病历:结果:共发现300例法洛四联症患者,其中18例患者肺动脉瓣缺失。他们平均接受了 8.2 年的随访。4名患者在产前确诊,13名患者在新生儿期确诊,平均年龄为4.5天。基因检测证实一名患者患有迪乔治综合征。五名患者在新生儿期接受了手术治疗,其余患者在幼儿期接受了手术治疗。虽然总体上没有手术死亡病例,也不需要再次手术,但也出现了各种病症:本研究概述了这一罕见畸形及其在发展中国家的治疗情况。
{"title":"Tetralogy of Fallot With Absent Pulmonary Valve Syndrome: The Experience of a Tertiary Care Center in a Developing Country","authors":"Aziz Farhat,&nbsp;Sujud Charanek,&nbsp;Rana Zareef,&nbsp;Issam El-Rassi,&nbsp;Fadi Bitar,&nbsp;Mariam Arabi","doi":"10.1111/echo.15942","DOIUrl":"10.1111/echo.15942","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Tetralogy of Fallot with an absent pulmonary valve is a very rare variant of tetralogy. It is characterized by absent valve tissue, severe pulmonary regurgitation, and secondary aneurysmal dilatation of the pulmonary arteries.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>In this study, we aim to investigate the clinical presentations, management strategies, and outcomes of patients with tetralogy of Fallot and absent pulmonary valve.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methodology</h3>\u0000 \u0000 <p>We retrospectively reviewed the charts of all patients who presented to the American University of Beirut Medical Center between January 2010 and December 2020 and who were diagnosed with this anomaly.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 300 cases of tetralogy of Fallot were identified, of which 18 patients had absent pulmonary valves. They were followed up for an average of 8.2 years. Prenatal diagnoses were made in four patients, while 13 patients were identified in the neonatal period, with an average age of 4.5 days. Genetic testing confirmed DiGeorge syndrome in one patient. Five patients underwent surgical intervention in the neonatal period, while the remaining patients were operated on during their early childhood. While overall there were no surgical mortalities nor any need for reinterventions, a variety of morbidities were encountered.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study provides an overview of this rare anomaly and its management in a developing country.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 10","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Left Ventricular Functional Impairment in Patients With Chronic Kidney Disease Using Three-Dimensional Speckle Tracking Imaging 利用三维斑点追踪成像评估慢性肾病患者的左心室功能障碍
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-05 DOI: 10.1111/echo.15928
Xue Gao, Weiwei Xiao, Liqin Ji, Houyu Li, Anlingzi Zou, Xinru Zhang, Zhuomeng Miao, Siyuan Yang, Shaomei Yu

Background

Chronic kidney disease (CKD) is strongly linked to the incidence and mortality of cardiovascular diseases (CVDs), with left ventricular myocardial damage being the most prevalent. This study aimed to assess left ventricle (LV) dysfunction using three-dimensional speckle tracking imaging (3D-STI) in CKD patients.

Methods

A total of 110 CKD patients and 55 healthy volunteers underwent echocardiography. CKD patients were divided into CKD1 group and CKD2 group based on the estimated glomerular filtration rate (eGFR). Assessing cardiac function via two-dimensional speckle tracking echocardiography (2D-STE) and three-dimensional speckle tracking echocardiography (3D-STE) parameters, with strain presented in absolute terms. Collecting and comparing clinical and echocardiographic parameters from three groups, assessing 3D-STI's value in evaluating LV functional impairment in CKD patients via correlation and receiver operating characteristic (ROC) curve analyses, and identifying risk factors for CKD progression to end-stage renal disease (ESRD) through univariate and multivariate analyses.

Results

In CKD2 group, 2D-left ventricular ejection fraction (LVEF), 3D-LVEF, 2D left ventricular global longitudinal strain (2D-LVGLS), 3D-LVGLS, and 3D-left ventricular global circumferential peak strain (LVGCS) significantly worsen compared to the control and CKD1 groups, with statistically significant distinctions between the latter two (all p < 0.05). The absolute value of 3D-LVGLS shows a robust correlation with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and serum creatinine (Scr) (r = −0.598, −0.649, both p < 0.001). ROC curve analysis indicates higher diagnostic efficacy of 3D-LVGLS and 3D-LVGCS for LV systolic function than 2D-LVGLS. Univariate and multivariate analyses reveal an independent association of 3D-LVGLS with the progression to ESRD in CKD.

Conclusion

3D-LVGLS and 3D-LVGCS effectively detect LV dysfunction in CKD patients. Specifically, 3D-LVGLS demonstrates a robust correlation with NT-proBNP and Scr and is independently linked to CKD progressing to ESRD.

背景:慢性肾脏病(CKD)与心血管疾病(CVDs)的发病率和死亡率密切相关,其中以左心室心肌损伤最为普遍。本研究旨在利用三维斑点追踪成像(3D-STI)评估慢性肾脏病患者的左心室(LV)功能障碍:方法:共有 110 名 CKD 患者和 55 名健康志愿者接受了超声心动图检查。根据估计的肾小球滤过率(eGFR),CKD 患者被分为 CKD1 组和 CKD2 组。通过二维斑点追踪超声心动图(2D-STE)和三维斑点追踪超声心动图(3D-STE)参数评估心脏功能,应变以绝对值表示。收集并比较三组患者的临床和超声心动图参数,通过相关性和接收器操作特征曲线(ROC)分析评估三维斑点追踪超声心动图在评估 CKD 患者左心室功能损伤方面的价值,并通过单变量和多变量分析确定 CKD 进展为终末期肾病(ESRD)的风险因素:结果:与对照组和CKD1组相比,CKD2组的二维左心室射血分数(LVEF)、三维左心室射血分数(3D-LVEF)、二维左心室全周纵向应变(2D-LVGLS)、三维左心室全周纵向应变(3D-LVGLS)和三维左心室全周峰值应变(LVGCS)明显恶化,后两者之间的差异有统计学意义(P均<0.05)。3D-LVGLS 的绝对值与 N 端前 B 型钠尿肽(NT-proBNP)和血清肌酐(Scr)呈显著相关性(r = -0.598,-0.649,均 p <0.001)。ROC曲线分析表明,3D-LVGLS和3D-LVGCS对左心室收缩功能的诊断效力高于2D-LVGLS。结论:3D-LVGLS 和 3D-LVGCS 能有效检测出 CKD 患者的左心室功能障碍。结论:3D-LVGLS 和 3D-LVGCS 能有效检测出 CKD 患者的左心室功能障碍,特别是 3D-LVGLS 与 NT-proBNP 和 Scr 有很强的相关性,并且与 CKD 进展到 ESRD 有独立联系。
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引用次数: 0
Advanced Echocardiography in Assessment of Subclinical Right Ventricular Dysfunction in Behcet's Disease 高级超声心动图在评估白塞氏病亚临床右心室功能障碍中的应用
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-10-04 DOI: 10.1111/echo.15935
Izhan Hamza, Masood Ahmad
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引用次数: 0
Left Ventricular Geometric Pattern Impacts QT Dispersion in Males Athletes and Sedentary Men 左心室几何形态对男性运动员和久坐男性 QT 弥散的影响
IF 1.6 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-09-30 DOI: 10.1111/echo.15937
Emilija Stojanović, Aaron Scanlan, Vladimir Jakovljević, Viktor Stoičkov, Dragan Radovanović

Aim

To (1) compare QT dispersion (QTd) and echocardiographic features between athletes with concentric left ventricular (LV) hypertrophy, athletes with eccentric LV hypertrophy, and sedentary controls with a normal LV geometric pattern and (2) quantify associations between QTd and echocardiographic features within these groups.

Methods

Male athletes competing in different sports and sedentary men were stratified into groups according to their LV geometric pattern. These groups included eccentric LV hypertrophy (LV index > 115 g/m2, relative wall thickness [RWT] < 0.42) consisting of 38 athletes, concentric LV hypertrophy (LV index > 115 g/m2, RWT > 0.42) consisting of 40 athletes, and normal LV geometric pattern (LV index < 115 g/m2, RWT < 0.42) consisting of 40 sedentary controls. Following a cross-sectional design, participants underwent electrocardiographic (ECG) and echocardiographic screening. Data were compared between groups using one-way analyses of variance with Bonferroni post hoc tests. Associations between corrected QTd and echocardiographic variables were quantified using Pearson correlations.

Results

Alongside structural disparities between groups, corrected QTd was significantly (p < 0.001) lower in athletes with eccentric LV hypertrophy compared to athletes with concentric LV hypertrophy and sedentary controls. Significant, moderate-to-very-large correlations were found between corrected QTd and interventricular septal wall thickness in athletes with concentric (r = 0.416, p = 0.008) or eccentric LV hypertrophy (r = 0.734, p < 0.001), and sedentary controls (r = 0.464, p = 0.003).

Conclusion

The provided comparative and relationship data may inform the development of more precise approaches for ECG and echocardiographic screening in athletes, particularly in those with concentric LV hypertrophy who may be at greater risk for developing prolonged QTd.

目的:(1)比较左心室同心性肥厚运动员、左心室偏心性肥厚运动员和左心室几何形态正常的静坐对照组之间的QT频散(QTd)和超声心动图特征;(2)量化这些组别中QTd和超声心动图特征之间的关联:方法:根据左心室几何形态将参加不同运动的男性运动员和久坐不动的男性分为不同组别。这些组别包括偏心性左心室肥厚(左心室指数> 115 g/m2,相对室壁厚度[RWT]< 0.42),由38名运动员组成;同心性左心室肥厚(左心室指数> 115 g/m2,RWT> 0.42),由40名运动员组成;正常左心室几何形态(左心室指数< 115 g/m2,RWT< 0.42),由40名久坐不动的对照组组成。采用横断面设计,参与者接受心电图(ECG)和超声心动图检查。组间数据采用单因素方差分析和Bonferroni事后检验进行比较。校正后的 QTd 与超声心动图变量之间的关联采用皮尔逊相关性进行量化:结果:除组间结构差异外,偏心性左心室肥厚运动员的校正 QTd 显著低于同心性左心室肥厚运动员和静坐对照组(p < 0.001)。在同心型(r = 0.416,p = 0.008)或偏心型左心室肥厚运动员(r = 0.734,p < 0.001)和久坐对照组(r = 0.464,p = 0.003)中,校正 QTd 与室间隔壁厚度之间存在显著的中度至高度相关性:所提供的比较和关系数据可为制定更精确的运动员心电图和超声心动图筛查方法提供参考,尤其是那些患有同心左心室肥厚的运动员,他们可能更容易出现 QTd 延长。
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引用次数: 0
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Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques
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