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Impact of ginger supplementation on serum PGE2, COX2, and IL-6 in response to exhaustive exercise in female taekwondo athletes 补充生姜对女性跆拳道运动员在剧烈运动后血清 PGE2、COX2 和 IL-6 反应的影响
Pub Date : 2024-02-07 DOI: 10.1163/17552559-20230041
S.Z. Karizak, M. Shahnehzad, A. Zar
Inflammation and muscle soreness sometimes occur after high-intensity exercise in some athletes. This study aimed to determine the effect of a ginger supplement period on serum cyclooxygenase-2 (COX2), prostaglandin E2 (PGE2), and interleukin (IL)-6 in response to exhaustive exercise in female taekwondo athletes. In this semi-experimental study, 24 semi-professional female taekwondo athletes (mean age 19.75 ± 2.03 years, height 160 ± 6 cm, weight 53.99 ± 7.49 kg) were selected voluntarily. Subjects were randomly assigned to the ginger supplement + exhaustive (GE + EE) and exhaustive exercise (EE) groups. 24 doses of 2,000 mg of pure ginger supplement (3 days/week for 8 weeks) were taken in the morning and evening (4 capsules of 500 mg: 2 in the morning and 2 in the evening). Then Bruce’s test was performed as an exhaustive exercise. Blood samples were collected in two stages before and after the intervention, and serum levels of COX2, PGE2, and IL-6 were measured using the Elisa method. T-tests and analysis of variance with repeated measures were used to examine intra-group changes and compare between groups from pre-test to post-test using SPSS version 25 software. The results showed a significant increase in the level of serum COX2 (), and no significant increase in the level of serum PGE2 () and IL-6 () in the EE group compared to baseline levels. Also, there was a significant decrease in the level of serum PGE2 (), COX2 (), and IL-6 () in the group of GE + EE compared to baseline levels. In addition, there was a significant difference between the group of GE + EE and the EE (). GE + EE group, in comparison with the EE group, partially reduced inflammation. Taking 8-weeks of ginger supplementations can effectively reduce muscle inflammation following exhaustive exercise in female taekwondo athletes.
一些运动员在高强度运动后有时会出现炎症和肌肉酸痛。本研究旨在确定生姜补充剂对女性跆拳道运动员在剧烈运动后血清环氧化酶-2(COX2)、前列腺素 E2(PGE2)和白细胞介素(IL)-6 的影响。在这项半实验研究中,自愿挑选了 24 名半专业女子跆拳道运动员(平均年龄为 19.75 ± 2.03 岁,身高 160 ± 6 厘米,体重 53.99 ± 7.49 千克)。受试者被随机分配到生姜补充剂+排气(GE + EE)组和排气运动(EE)组。受试者早晚各服用 24 次 2,000 毫克纯生姜补充剂(每周 3 天,共 8 周)(4 粒 500 毫克的胶囊:早晚各 2 粒)。然后进行布鲁斯测试。干预前后分两次采集血样,用 Elisa 法测定血清中 COX2、PGE2 和 IL-6 的水平。使用 SPSS 25 版软件进行 T 检验和重复测量方差分析,以检验组内变化并比较组间从试验前到试验后的变化。结果显示,与基线水平相比,EE 组的血清 COX2()水平明显升高,而血清 PGE2()和 IL-6()水平没有明显升高。此外,与基线水平相比,GE + EE 组的血清 PGE2()、COX2()和 IL-6 ()水平明显下降。此外,GE + EE 组与 EE 组之间也存在明显差异()。与 EE 组相比,GE + EE 组部分减轻了炎症。为期 8 周的生姜补充剂可有效减轻女性跆拳道运动员在剧烈运动后的肌肉炎症。
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引用次数: 0
Impact of ginger supplementation on serum PGE2, COX2, and IL-6 in response to exhaustive exercise in female taekwondo athletes 补充生姜对女性跆拳道运动员在剧烈运动后血清 PGE2、COX2 和 IL-6 反应的影响
Pub Date : 2024-02-07 DOI: 10.1163/17552559-20230041
S.Z. Karizak, M. Shahnehzad, A. Zar
Inflammation and muscle soreness sometimes occur after high-intensity exercise in some athletes. This study aimed to determine the effect of a ginger supplement period on serum cyclooxygenase-2 (COX2), prostaglandin E2 (PGE2), and interleukin (IL)-6 in response to exhaustive exercise in female taekwondo athletes. In this semi-experimental study, 24 semi-professional female taekwondo athletes (mean age 19.75 ± 2.03 years, height 160 ± 6 cm, weight 53.99 ± 7.49 kg) were selected voluntarily. Subjects were randomly assigned to the ginger supplement + exhaustive (GE + EE) and exhaustive exercise (EE) groups. 24 doses of 2,000 mg of pure ginger supplement (3 days/week for 8 weeks) were taken in the morning and evening (4 capsules of 500 mg: 2 in the morning and 2 in the evening). Then Bruce’s test was performed as an exhaustive exercise. Blood samples were collected in two stages before and after the intervention, and serum levels of COX2, PGE2, and IL-6 were measured using the Elisa method. T-tests and analysis of variance with repeated measures were used to examine intra-group changes and compare between groups from pre-test to post-test using SPSS version 25 software. The results showed a significant increase in the level of serum COX2 (), and no significant increase in the level of serum PGE2 () and IL-6 () in the EE group compared to baseline levels. Also, there was a significant decrease in the level of serum PGE2 (), COX2 (), and IL-6 () in the group of GE + EE compared to baseline levels. In addition, there was a significant difference between the group of GE + EE and the EE (). GE + EE group, in comparison with the EE group, partially reduced inflammation. Taking 8-weeks of ginger supplementations can effectively reduce muscle inflammation following exhaustive exercise in female taekwondo athletes.
一些运动员在高强度运动后有时会出现炎症和肌肉酸痛。本研究旨在确定生姜补充剂对女性跆拳道运动员在剧烈运动后血清环氧化酶-2(COX2)、前列腺素 E2(PGE2)和白细胞介素(IL)-6 的影响。在这项半实验研究中,自愿挑选了 24 名半专业女子跆拳道运动员(平均年龄为 19.75 ± 2.03 岁,身高 160 ± 6 厘米,体重 53.99 ± 7.49 千克)。受试者被随机分配到生姜补充剂+排气(GE + EE)组和排气运动(EE)组。受试者早晚各服用 24 次 2,000 毫克纯生姜补充剂(每周 3 天,共 8 周)(4 粒 500 毫克的胶囊:早晚各 2 粒)。然后进行布鲁斯测试。干预前后分两次采集血样,用 Elisa 法测定血清中 COX2、PGE2 和 IL-6 的水平。使用 SPSS 25 版软件进行 T 检验和重复测量方差分析,以检验组内变化并比较组间从试验前到试验后的变化。结果显示,与基线水平相比,EE 组的血清 COX2()水平明显升高,而血清 PGE2()和 IL-6()水平没有明显升高。此外,与基线水平相比,GE + EE 组的血清 PGE2()、COX2()和 IL-6 ()水平明显下降。此外,GE + EE 组与 EE 组之间也存在明显差异()。与 EE 组相比,GE + EE 组部分减轻了炎症。为期 8 周的生姜补充剂可有效减轻女性跆拳道运动员在剧烈运动后的肌肉炎症。
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引用次数: 0
Correlation of detrended fluctuation analysis alpha 1 with blood lactate concentration in field standardised exercise tests in sport horses 在运动马的现场标准化运动测试中,去趋势波动分析α1与血液乳酸浓度的相关性
Pub Date : 2024-02-07 DOI: 10.1163/17552559-20230024
K. Murphy, C. Solomon, D. Stefanovski, O. Lorello, M. Robinson, J. Haughan, C. Navas de Solis
Methods to determine exercise intensity thresholds, such as the aerobic and anaerobic threshold, that separate different exercise intensities in exercising horses in the field setting or on the treadmill often require equipment, standardised conditions and/or blood sampling. Detrended fluctuation analysis (DFA) is a heart rate variability variable proposed as a non-invasive tool for exercise intensity monitoring and with a potential association with exercise intensity thresholds and fatigue. The objectives of this study were to (1) describe the first component of DFA (DFA-α1) during standardised field incremental exercise tests in sport horses in active Eventing competition and in sport horses ridden without the goal of participating in competitions, and (2) to determine if DFA-α1 is associated with blood lactate concentration. Null hypotheses of the study were that (1) DFA-α1 is not correlated with blood lactate concentration measurements and (2) the correlation between DFA-α1 and blood lactate concentration is not stronger than the one between blood lactate concentration and heart rate or blood lactate concentration and speed. An in vivo observational study was performed analysing exercising electrocardiograms obtained in 59 standardised exercise tests in the field. DFA-α1 was significantly and moderately correlated with blood lactate concentration (, ). A strong correlation was observed between blood lactate concentration and speed (, ), as well as between blood lactate concentration and heart rate (, ). DFA-α1 correlation with blood lactate concentration was moderate but weaker than the correlation of blood lactate concentration and heart rate or blood lactate concentration and speed. DFA-α1 was not a useful surrogate of blood lactate concentration in field incremental standardised tests used for sport horses in this setting.
确定运动强度阈值(如有氧阈值和无氧阈值)的方法通常需要设备、标准化条件和/或血液采样,以区分运动马匹在野外环境或跑步机上的不同运动强度。去趋势波动分析(DFA)是一种心率变异性变量,被提议作为运动强度监测的非侵入性工具,并可能与运动强度阈值和疲劳有关。本研究的目的是:(1) 描述在积极参加赛事的运动马匹和不以参加赛事为目标的运动马匹进行标准化野外增量运动测试时的 DFA 第一成分(DFA-α1);(2) 确定 DFA-α1 是否与血液乳酸浓度有关。该研究的零假设是:(1)DFA-α1 与血液乳酸浓度测量值不相关;(2)DFA-α1 与血液乳酸浓度之间的相关性不强于血液乳酸浓度与心率或血液乳酸浓度与速度之间的相关性。一项体内观察研究分析了在 59 次实地标准化运动测试中获得的运动心电图。DFA-α1 与血液乳酸浓度有明显的中度相关性(,)。在血液乳酸浓度与速度(, )以及血液乳酸浓度与心率(, )之间观察到了很强的相关性。DFA-α1 与血乳酸浓度的相关性中等,但弱于血乳酸浓度与心率或血乳酸浓度与速度的相关性。在这种情况下,DFA-α1 并不是运动马匹进行现场增量标准化测试时血乳酸浓度的有效替代指标。
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引用次数: 0
Impact of anti-gravity muscle training protocol on plantar pressure, pain threshold and foot posture on chronic painful heel: an RCT study 反重力肌肉训练方案对慢性足跟疼痛患者足底压力、疼痛阈值和足部姿势的影响:一项 RCT 研究
Pub Date : 2024-01-19 DOI: 10.1163/17552559-20230036
S. Gotecha, P. Gurudut, A. Welling, V. Kage
Chronic painful heel (CPH) is a symptom of an underlying condition caused due to obesity, excessive foot pronation, tightness of Tendo-Achilles (TA), excessive running, and sedentary life. The antigravity muscles (AGM) atrophy results due to long working hours in sitting, leading to their deteriorating relationship with gravity thereby reduced sensitivity to its force. Hence, need arises to explore training effects of AGM protocol on CPH condition. A randomised controlled trial was conducted on thirty individuals with CPH allocated randomly to two study groups viz. AGMT (n = 15) and Control group (n = 15) who received intervention for twelve sessions over four weeks. Control group received conventional physiotherapy in form of therapeutic ultrasound and exercises while AGMT received conventional physiotherapy using the AGMT protocol. Outcomes assessed were plantar pressure and foot posture assessed using Harris mat, muscle strength by dynamometer, pain threshold with pressure algometer, and foot functions using Foot and Ankle Ability Measure Scale (FAAM) which were taken at pre- and post-training. The between group analysis of data revealed that foot posture, plantar pressure and muscle strength, pain threshold were significantly better in the AGMT group than in the Control group ( 0.0001), while pain intensity (P = 0.3952) and foot functions (P = 0.2372) were equally effective in both the study groups. In conclusion, the AGMT protocol along with conventional physiotherapy proved to be a promising training protocol for individuals with CPH showing positive outcomes in comparison to conventional therapy alone, suggesting to incorporate AGM strengthening alongside conventional therapy to obtain better clinical outcomes.Trial registration: This trial was prospectively registered in the Clinical trial registry of India with registration number CTRI/2022/10/046138.
慢性足跟痛(CPH)是由于肥胖、足部过度前倾、跟腱紧绷(TA)、过度跑步和久坐引起的潜在疾病症状。由于长时间坐着工作,反重力肌(AGM)萎缩,导致其与重力的关系恶化,从而降低了对重力的敏感性。因此,有必要探讨反重力肌训练方案对 CPH 状况的影响。研究人员对 30 名 CPH 患者进行了随机对照试验,将他们随机分配到两个研究组,即 AGMT 组(15 人)和对照组(15 人),接受为期四周、共 12 节课的干预。对照组接受传统的物理治疗,包括超声波治疗和运动,而 AGMT 组则接受 AGMT 方案的传统物理治疗。评估结果包括使用哈里斯垫评估足底压力和足部姿势,使用测力计评估肌肉力量,使用压力阈值计评估疼痛阈值,以及使用足踝能力测量量表(FAAM)评估足部功能。组间数据分析显示,AGMT 组的足部姿势、足底压力和肌肉力量、疼痛阈值明显优于对照组(0.0001),而疼痛强度(P = 0.3952)和足部功能(P = 0.2372)在两组研究中效果相同。总之,AGMT方案与传统物理疗法相结合,对CPH患者来说是一种很有前景的训练方案,与单纯的传统疗法相比,显示出积极的疗效,建议在传统疗法的基础上结合AGM强化训练,以获得更好的临床疗效:该试验已在印度临床试验登记处进行了前瞻性登记,登记号为 CTRI/2022/10/046138。
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引用次数: 0
Corrigendum on: Self-reported acute injury and chronic pain in American equestrian athletes 更正:美国马术运动员自我报告的急性损伤和慢性疼痛
Pub Date : 2024-01-16 DOI: 10.1163/17552559-2024x001
M. Keener, K. Tumlin
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引用次数: 0
Body measurements in Icelandic horses used for two different purposes and the relationship to performance and usability 用于两种不同用途的冰岛马的身体测量结果以及与性能和实用性的关系
Pub Date : 2024-01-11 DOI: 10.1163/17552559-20230034
D. Söderroos, G. Stefánsdóttir, V. Gunnarsson, M. Rhodin, S. Ragnarsson, A. Jansson
Many horse breeds are used for a variety of tasks and studies have shown within breed variations in conformation depending on the task. The Icelandic horse is used for several tasks, e.g. leisure riding, competitions and tour riding. Research about conformation and relationship to subjectively assessed performance (usability) in Icelandic horses used by tourist companies and riding schools (TRh) are lacking. Back condition score has been shown to be associated with weight carrying capacity in the breed. However, the association between back condition score and angle and performance in Icelandic horses participating in a breed evaluation field test (BEFTh) and usability in TRh has not been investigated previously. The aim of the study was to compare body measurements in BEFTh and TRh and examine the relationship with riding ability in BEFTh and usability in TRh. Data of height at withers, back and croup, body condition score (BCS) and back angle were collected in 48 BEFTh (age 8 ± 2 years) and 65 TRh (age 14 ± 5 years). Transversal back angle at the 18th thoracic vertebra was determined using a flexible curve ruler. A questionnaire was used to evaluate the relationship between body measurements and owners’ assessment of usability in TRh. The relationship between back condition score and angle and riding ability was evaluated in BEFTh. Compared with TRh, BEFTh had a greater difference between height at withers and height at back and croup, lower BCS and greater back angle (). In TRh, height were positively correlated with usability (). Back condition score and angle were not associated with riding ability in BEFTh or usability in TRh (). In conclusion, body measurements differs between BEFTh and TRh and further studies are needed to investigate if the same conformation traits are associated with good performance in BEFTh and usability in TRh.
许多马的品种都能胜任各种任务,研究表明,根据任务的不同,不同品种的马在体形上也有差异。冰岛马可用于多种任务,如休闲骑乘、比赛和旅游骑乘。目前还缺乏对旅游公司和骑术学校(TRh)使用的冰岛马的体形以及与主观评估性能(可用性)之间关系的研究。研究表明,马匹的背部状况评分与马匹的负重能力有关。然而,此前尚未研究过参加品种评估现场测试(BEFTh)的冰岛马的背部状况评分和角度与性能之间的关系,以及TRh的可用性。本研究的目的是比较 BEFTh 和 TRh 的身体测量数据,并研究与 BEFTh 骑乘能力和 TRh 可用性之间的关系。研究收集了 48 头 BEFTh(8 岁 ± 2 岁)和 65 头 TRh(14 岁 ± 5 岁)马的肩高、背高和脊背高、身体状况评分(BCS)和背角数据。使用柔性曲线尺测定第 18 胸椎处的横向背部角度。调查问卷用于评估身体测量值与车主对 TRh 可用性评估之间的关系。对BEFTh的背部状况评分和角度与骑乘能力之间的关系进行了评估。与TRh相比,BEFTh的肩高与背高和颈高之间的差异更大,BCS更低,背角更大()。在 TRh 中,身高与可用性呈正相关()。BEFTh的背部状况评分和角度与骑乘能力无关,TRh的可用性也与骑乘能力无关()。总之,BEFTh 和 TRh 的体型测量结果不同,需要进一步研究相同的体型特征是否与 BEFTh 的良好表现和 TRh 的可用性相关。
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Comparative Exercise Physiology
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