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Classification of bioactive peptides: a systematic benchmark of models and encodings 生物活性肽的分类:模型和编码的系统基准
Pub Date : 2024-05-01 DOI: 10.1016/j.csbj.2024.05.040
Edoardo Bizzotto, Guido Zampieri, Laura Treu, Pasquale Filannino, Raffaella Di Cagno, Stefano Campanaro
{"title":"Classification of bioactive peptides: a systematic benchmark of models and encodings","authors":"Edoardo Bizzotto, Guido Zampieri, Laura Treu, Pasquale Filannino, Raffaella Di Cagno, Stefano Campanaro","doi":"10.1016/j.csbj.2024.05.040","DOIUrl":"https://doi.org/10.1016/j.csbj.2024.05.040","url":null,"abstract":"","PeriodicalId":505673,"journal":{"name":"Computational and Structural Biotechnology Journal","volume":"167 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141133654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles 针对可溶解的疏水和静电斑块的抗体突变的生物物理筛选框架,以增强粘度曲线
Pub Date : 2024-05-01 DOI: 10.1016/j.csbj.2024.05.041
Georgina B Armstrong, Vidhi Shah, Paula Sanches, Mitul Patel, Ricky Casey, Craig J Jamieson, Glenn A Burley, William J Lewis, Zahra Rattray
{"title":"A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles","authors":"Georgina B Armstrong, Vidhi Shah, Paula Sanches, Mitul Patel, Ricky Casey, Craig J Jamieson, Glenn A Burley, William J Lewis, Zahra Rattray","doi":"10.1016/j.csbj.2024.05.041","DOIUrl":"https://doi.org/10.1016/j.csbj.2024.05.041","url":null,"abstract":"","PeriodicalId":505673,"journal":{"name":"Computational and Structural Biotechnology Journal","volume":" 98","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141132503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insulin-related traits and prostate cancer: a Mendelian randomization study 胰岛素相关特征与前列腺癌:孟德尔随机研究
Pub Date : 2024-05-01 DOI: 10.1016/j.csbj.2024.05.034
Guihua Chen, Yi Wang, Xiang Wang
{"title":"Insulin-related traits and prostate cancer: a Mendelian randomization study","authors":"Guihua Chen, Yi Wang, Xiang Wang","doi":"10.1016/j.csbj.2024.05.034","DOIUrl":"https://doi.org/10.1016/j.csbj.2024.05.034","url":null,"abstract":"","PeriodicalId":505673,"journal":{"name":"Computational and Structural Biotechnology Journal","volume":"12 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141137706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causal association and shared genetics between telomere length and COVID-19 outcomes: new evidence from the latest large-scale summary statistics 端粒长度与 COVID-19 结果之间的因果关系和共享遗传学:来自最新大规模汇总统计的新证据
Pub Date : 2024-05-01 DOI: 10.1016/j.csbj.2024.05.012
Jingwei Zhang, Jie Wen, Ziyu Dai, Hao Zhang, Nan Zhang, Ruoyan Lei, Zhixiong Liu, Luo Peng, Quan Cheng
{"title":"Causal association and shared genetics between telomere length and COVID-19 outcomes: new evidence from the latest large-scale summary statistics","authors":"Jingwei Zhang, Jie Wen, Ziyu Dai, Hao Zhang, Nan Zhang, Ruoyan Lei, Zhixiong Liu, Luo Peng, Quan Cheng","doi":"10.1016/j.csbj.2024.05.012","DOIUrl":"https://doi.org/10.1016/j.csbj.2024.05.012","url":null,"abstract":"","PeriodicalId":505673,"journal":{"name":"Computational and Structural Biotechnology Journal","volume":"41 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141030003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Multi-omic Single-cell Landscape of Cellular Diversification in the Developing Human Cerebral Cortex 发育中人类大脑皮层细胞多样化的多原子单细胞图谱
Pub Date : 2024-05-01 DOI: 10.1016/j.csbj.2024.05.019
Yuhan Tian, Xia Wu, Songhao Luo, Dan Xiong, Rong Liu, Lanqi Hu, Yuchen Yuan, Guowei Shi, Junjie Yao, Zhiwei Huang, Fang Fu, Xin Yang, Zhonghui Tang, Jiajun Zhang, Kunhua Hu
{"title":"A Multi-omic Single-cell Landscape of Cellular Diversification in the Developing Human Cerebral Cortex","authors":"Yuhan Tian, Xia Wu, Songhao Luo, Dan Xiong, Rong Liu, Lanqi Hu, Yuchen Yuan, Guowei Shi, Junjie Yao, Zhiwei Huang, Fang Fu, Xin Yang, Zhonghui Tang, Jiajun Zhang, Kunhua Hu","doi":"10.1016/j.csbj.2024.05.019","DOIUrl":"https://doi.org/10.1016/j.csbj.2024.05.019","url":null,"abstract":"","PeriodicalId":505673,"journal":{"name":"Computational and Structural Biotechnology Journal","volume":"108 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141037557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In silico and in vivo analysis reveal impact of c-Myc tag in FMC63 scFv-CD19 protein interface and CAR-T cell efficacy 硅学和体内分析揭示了 c-Myc 标签对 FMC63 scFv-CD19 蛋白界面和 CAR-T 细胞疗效的影响
Pub Date : 2024-05-01 DOI: 10.1016/j.csbj.2024.05.032
Ana Julia Ferreira Lima, K. Hajdu, Luiza Abdo, L. R. Batista-Silva, Clara de Oliveira Andrade, E. Correia, E. Aragão, Martín Bonamino, M. Lourenzoni
{"title":"In silico and in vivo analysis reveal impact of c-Myc tag in FMC63 scFv-CD19 protein interface and CAR-T cell efficacy","authors":"Ana Julia Ferreira Lima, K. Hajdu, Luiza Abdo, L. R. Batista-Silva, Clara de Oliveira Andrade, E. Correia, E. Aragão, Martín Bonamino, M. Lourenzoni","doi":"10.1016/j.csbj.2024.05.032","DOIUrl":"https://doi.org/10.1016/j.csbj.2024.05.032","url":null,"abstract":"","PeriodicalId":505673,"journal":{"name":"Computational and Structural Biotechnology Journal","volume":"22 3‐4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive integration of single-cell RNA and transcriptome RNA sequencing to establish a pyroptosis-related signature for improving prognostic prediction of gastric cancer 全面整合单细胞 RNA 和转录组 RNA 测序,建立胃癌预后预测的热蛋白沉积相关特征
Pub Date : 2024-02-01 DOI: 10.1016/j.csbj.2024.02.002
Jie Li, Tian Yu, Juan Sun, M. Ma, Zicheng Zheng, Weiming Kang, Xin Ye
{"title":"Comprehensive integration of single-cell RNA and transcriptome RNA sequencing to establish a pyroptosis-related signature for improving prognostic prediction of gastric cancer","authors":"Jie Li, Tian Yu, Juan Sun, M. Ma, Zicheng Zheng, Weiming Kang, Xin Ye","doi":"10.1016/j.csbj.2024.02.002","DOIUrl":"https://doi.org/10.1016/j.csbj.2024.02.002","url":null,"abstract":"","PeriodicalId":505673,"journal":{"name":"Computational and Structural Biotechnology Journal","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139819496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computational Design of α-amylase from Bacillus licheniformis to Increase Its Activity and Stability at High Temperatures 计算设计地衣芽孢杆菌的 α 淀粉酶,提高其在高温下的活性和稳定性
Pub Date : 2024-02-01 DOI: 10.1016/j.csbj.2024.02.005
S. Fan, Xudong Lü, Xiyu Wei, Ruijie Lü, Cuiyue Feng, Yuanyuan Jin, Maocai Yan, Zhaoyong Yang
{"title":"Computational Design of α-amylase from Bacillus licheniformis to Increase Its Activity and Stability at High Temperatures","authors":"S. Fan, Xudong Lü, Xiyu Wei, Ruijie Lü, Cuiyue Feng, Yuanyuan Jin, Maocai Yan, Zhaoyong Yang","doi":"10.1016/j.csbj.2024.02.005","DOIUrl":"https://doi.org/10.1016/j.csbj.2024.02.005","url":null,"abstract":"","PeriodicalId":505673,"journal":{"name":"Computational and Structural Biotechnology Journal","volume":"21 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139822455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Limits of Prediction: Why Intrinsically Disordered Regions Challenge Our Understanding of Antimicrobial Peptides 预测的局限:本质上无序的区域为何挑战我们对抗菌肽的理解
Pub Date : 2024-02-01 DOI: 10.1016/j.csbj.2024.02.008
Roberto Bello-Madruga, Marc Torrent Burgas
{"title":"The Limits of Prediction: Why Intrinsically Disordered Regions Challenge Our Understanding of Antimicrobial Peptides","authors":"Roberto Bello-Madruga, Marc Torrent Burgas","doi":"10.1016/j.csbj.2024.02.008","DOIUrl":"https://doi.org/10.1016/j.csbj.2024.02.008","url":null,"abstract":"","PeriodicalId":505673,"journal":{"name":"Computational and Structural Biotechnology Journal","volume":"74 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139873819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automated Machine Learning in Nanotoxicity Assessment: A Comparative Study of Predictive Model Performance 纳米毒性评估中的自动机器学习:预测模型性能比较研究
Pub Date : 2024-02-01 DOI: 10.1016/j.csbj.2024.02.003
Xiao Xiao, T. X. Trinh, Zayakhuu Gerelkhuu, Eunyong Ha, Tae Hyun Yoon
{"title":"Automated Machine Learning in Nanotoxicity Assessment: A Comparative Study of Predictive Model Performance","authors":"Xiao Xiao, T. X. Trinh, Zayakhuu Gerelkhuu, Eunyong Ha, Tae Hyun Yoon","doi":"10.1016/j.csbj.2024.02.003","DOIUrl":"https://doi.org/10.1016/j.csbj.2024.02.003","url":null,"abstract":"","PeriodicalId":505673,"journal":{"name":"Computational and Structural Biotechnology Journal","volume":"41 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139818039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Computational and Structural Biotechnology Journal
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