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THANK YOU TO DEVELOPING WORLD BIOETHICS REVIEWERS 感谢发展中国家的生物伦理审稿人
IF 1 3区 哲学 Q3 ETHICS Pub Date : 2025-12-05 DOI: 10.1111/dewb.70009
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引用次数: 0
Beyond Affordability: The Bioethics of Inclusion and Justice in Advanced Therapies. 超越负担能力:先进治疗中包容和公正的生物伦理。
IF 1 3区 哲学 Q3 ETHICS Pub Date : 2025-11-16 DOI: 10.1111/dewb.70013
Carlos M Ardila, Anny Marcela Vivares-Builes, Eliana Pineda-Vélez
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引用次数: 0
Brazil's Ethical Research Framework Is Under Threat-And the Pharmaceutical Industry Stands to Gain. 巴西的伦理研究框架正面临威胁——制药业将从中获益。
IF 1 3区 哲学 Q3 ETHICS Pub Date : 2025-11-15 DOI: 10.1111/dewb.70012
Fernando Augusto Lima Marson
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引用次数: 0
What Retractions Tell Us About Research Integrity in Mexican Academia. 撤稿告诉我们墨西哥学术界的研究诚信。
IF 1 3区 哲学 Q3 ETHICS Pub Date : 2025-11-14 DOI: 10.1111/dewb.70011
Karina Ordoñez-Torres, Sergio Litewka, Elizabeth Heitman

Research integrity remains a challenge to public trust in science around the world. Retracted scientific papers can erode the public's trust by raising doubt about the reliability of the published literature. This paper assesses article retractions involving Mexican authors through analysis of relevant data and retraction patterns. The study examines 55 retracted articles with Mexican corresponding authors, categorizing them by publication venue, article type, scientific area, reasons for retraction, and time between publication and retraction. The findings underscore core challenges to research integrity in Mexico and the need to strengthen both research training and research integrity initiatives in Mexican research institutions. The paper concludes with recommendations for contextually relevant strategies for Mexican academia to foster research integrity.

研究诚信仍然是全世界公众对科学信任的一个挑战。撤稿的科学论文会让公众对已发表文献的可靠性产生怀疑,从而削弱公众的信任。本文通过分析相关数据和撤稿模式来评估涉及墨西哥作者的文章撤稿。该研究检查了55篇由墨西哥通讯作者撤回的文章,并根据发表地点、文章类型、科学领域、撤回原因以及发表和撤回之间的时间对它们进行了分类。这些发现强调了墨西哥科研诚信面临的核心挑战,以及加强墨西哥科研机构的科研培训和科研诚信举措的必要性。论文最后为墨西哥学术界促进研究诚信的相关战略提出了建议。
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引用次数: 0
Ubuntu Vis-à-Vis the Saying "We Are All in This Together" in the Context of the COVID-19 Pandemic. Ubuntu Vis-à-Vis在COVID-19大流行背景下的“我们都在一起”这句话。
IF 1 3区 哲学 Q3 ETHICS Pub Date : 2025-10-30 DOI: 10.1111/dewb.70010
John Mark Ogu

This article analyzes the interplay between Ubuntu's philosophy: "I am, because we are; and because we are, therefore I am" with the expression "We are all in this together," which resounded mostly in North America and Europe during the COVID-19 pandemic. This article argues that the expression "We are all in this together" directly or indirectly adopted Ubuntu's philosophy of relational solidarity in handling and navigating the COVID-19 pandemic. The expression implicitly acknowledges that pandemics can be mitigated through collaboration, shared responsibility, and relational solidarity.

本文分析了Ubuntu哲学之间的相互作用:“我存在,因为我们存在;因为我们在一起,所以我在一起”。在2019冠状病毒病大流行期间,这句话主要在北美和欧洲回响。本文认为,在处理和应对COVID-19大流行时,“我们都在一起”这一表达直接或间接地采用了Ubuntu的关系团结理念。这一表述含蓄地承认,可以通过合作、分担责任和相互关系的团结来缓解大流行病。
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引用次数: 0
Being the index-case: For an ethics of reciprocity 作为示范案例:互惠伦理。
IF 1 3区 哲学 Q3 ETHICS Pub Date : 2025-10-22 DOI: 10.1111/dewb.70008
Debora Diniz, Arbel Griner, Patricia Kingori
<p>Public health experts and research protocols trace disease outbreaks back to their potential origins.1 These investigations can focus on one person or a whole community. The effort is to identify the first case of a new infection, trace how far and at what pace the new disease is spreading, and understand and anticipate the best ways to contain it. Once “patient zero” or the “index case” is identified, the scientific community races to understand the evidence better. However, naming someone or a community as the origin case has ethical implications that deserves more reflection in bioethics and research ethics.2 To start, tying an outbreak to one person or community—with a specific status, gender and other social determinants—narrows down causality and responsibility, placing blame on an event or subject, and obscuring wider structures favoring disease occurrence and spread.3 Through our fieldwork with communities affected by health emergencies, we have witnessed the identification of “index cases.” This has inspired us to explore how persons and communities circulate subjectivities related to the status of being reference cases, and what they expect from scientists as being an index case becomes part of their lived experience.</p><p>In the past ten years, we have listened to stories from persons identified as the first cases of vertical transmission of Zika, to families related to the first documented events of maternal mortality from Covid-19, and, now, the primary vertical transmission of Oropouche fever in Brazil.4 Nathalia Neri, 33, shared her story surrounded by family members who work at the local public health facility. Nathalia's family lives in Rio Formoso, a community in Brazil that was devastated by the Zika epidemic in 2015 and remains in a permanent state of response to endemic arboviruses outbreaks. In 2024, her mother, a community health worker, noticed a new disease emerging in the village. Clinics were full of people, however, testing negative for Dengue, Zika, and Chikungunya.</p><p>Nathalia's mother decided to collect her daughter's blood sample for health surveillance because “something seemed unusual for mild Dengue or Zika.” She requested a test for the Oropouche virus, which was not easily accessible via the public health system. Nathalia tested negative. The mother had decided to closely monitor her pregnancy, as she remained intrigued by Nathalia's clinical symptoms, and was the one who notified the state's health secretary and researchers of her suspicion of fetal loss. Nathalia agreed to an autopsy on her daughter, extending the trust she had in her mother to scientists and medical personnel. The research team found the Oropouche virus in several of the fetus's organs and published a paper supporting the hypothesis that the Oropouche virus is vertically transmitted and can lead to fetal death.5</p><p>In strict terms, the research team and policymakers followed the best practices of a research protocol. Nathalia was
暂停监测和准备应对Oropouche,以及Nathalia的索引病例情况,并没有降低她的期望或她对意义的追求。作为零号病人现在是她主观性的一部分,是她如何看待自己的一部分,而不是公共卫生问题和监测人员对她的看法。我们遵循这个过程。不只是作为中立的旁观者,而是作为社会科学研究人员,娜塔莉亚的期望也是写作的一部分。我们拜访了娜塔莉亚和她的家人,收集了故事、照片和文件,随着时间的推移,我们也减少了出现的强度。娜塔莉亚想要更多。她想知道我们在写什么,我们是如何讲述她的故事的。我们与她分享了这篇社论的第一手资料。她在新闻中搜索有关女性的信息。每当她讲述自己的故事时,她都称自己为“零号病人”或“第一个病例”。她希望我们写的关于她的文章上都有她的名字,因为“这是我的故事,”她解释说。和她一起,我们开始考虑将某人命名为“第一人”的伦理含义——这是卫生紧急事件历史上独一无二的称号——以及它如何影响一个人在疾病中幸存的生活经历。作为研究人员,我们如何与研究对象建立一种互惠的伦理?对于nathalia——也许还有其他有索引案例潜力的人——我们暂时提出三条建议。首先,涉及与人们和社区接触的研究也涉及建立信任、培养长期关系和负责任。研究的总体过程规定了一个特定的交流时间表——调查、分析、发表——但这样的结构并不能反映任何真正关系的时间。在协议达成后,人们和社区会继续寻找信息和寻求联系。其次,收集和并列数据和样本的科学家和公共卫生官员应该与纳塔利亚分享的不仅仅是一篇带有公式和数字的学术论文。我们应该提供可理解的信息,说明已经发现的情况,包括调查路径、缺失的数据以及其他挑战、担忧和不确定性。我们应该总是说出个人索引条件的真相,我们的解释,并让那些参与研究的人获得共享的、科学授权的“不知道”。第三,我们应该培养一种互惠的伦理,这种伦理超越了将科学文章的发表作为成就或终点,同时解决公共卫生难题,并终止由同一问题引发的关系。作者声明无利益冲突。
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引用次数: 0
Reframing Justice in Healthcare AI: An Ubuntu-Based Approach for Africa. 重塑医疗保健人工智能中的正义:非洲基于ubuntu的方法。
IF 1 3区 哲学 Q3 ETHICS Pub Date : 2025-10-15 DOI: 10.1111/dewb.70007
Aloysius Ochasi, Abdoul Jalil Djiberou Mahamadou, Russ B Altman, Levi U C Nkwocha

There is an ongoing debate on how to balance the benefits and risks of artificial intelligence (AI), especially in healthcare. In resource-constrained settings, such as Africa, where access to quality care remains a challenge, AI has the potential to improve efficiency, accessibility, and patient outcomes. Yet, its development and deployment raise complex ethical, legal, ecological, and socioeconomic concerns. To ensure context-sensitive solutions, this paper introduces Ubuntu, a traditional African ethical philosophy, as a guiding framework for AI in African healthcare. Ubuntu offers a people-centered alternative to dominant Western-centric models, providing a culturally grounded lens for interpreting justice-related principles in line with Africa's unique needs and realities. Drawing on Ubuntu's five core values of communalism, interdependence, humanism, sharing, and compassion, we analyze how these principles can ethically guide AI across three normative pillars: justice and fairness, solidarity, and sustainability. For each, we identify risks and offer concrete, culturally resonant strategies to address them. In doing so, we undertake a distinctive scholarly contribution that meaningfully enriches the emerging discourse on decolonizing AI by reframing Ubuntu not only as a moral compass but also as a strategic tool for structural reform and innovation.

关于如何平衡人工智能(AI)的好处和风险,特别是在医疗保健领域,一直存在争论。在资源受限的环境中,如非洲,获得优质医疗服务仍然是一个挑战,人工智能有可能提高效率、可及性和患者的治疗效果。然而,它的发展和部署引发了复杂的伦理、法律、生态和社会经济问题。为了确保上下文敏感的解决方案,本文介绍了Ubuntu,一种传统的非洲伦理哲学,作为人工智能在非洲医疗保健的指导框架。Ubuntu为主导的西方中心模式提供了一个以人为本的选择,提供了一个基于文化的视角,根据非洲独特的需求和现实来解释与正义相关的原则。根据Ubuntu的五个核心价值观:社群主义、相互依存、人文主义、分享和同情,我们分析了这些原则如何在道德上指导人工智能跨越三个规范支柱:正义和公平、团结和可持续性。对于每一个问题,我们都能识别风险,并提供具体的、文化上能引起共鸣的策略来解决它们。在这样做的过程中,我们承担了一个独特的学术贡献,通过重新构建Ubuntu,不仅作为道德指南针,而且作为结构改革和创新的战略工具,有意义地丰富了关于非殖民化人工智能的新兴话语。
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引用次数: 0
A 'Neopotterian Theory of Global Bioethics': Additional Moral Frameworks and Bio-Ethical Criteria for Asia and Europe. “全球生命伦理学的新派理论”:亚洲和欧洲的附加道德框架和生物伦理标准。
IF 1 3区 哲学 Q3 ETHICS Pub Date : 2025-10-08 DOI: 10.1111/dewb.70006
Henri-Corto Stoeklé, Christian Hervé
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引用次数: 0
When Austerity Kills: The Ethical Cost of US HIV/AIDS Policy Shifts 《当紧缩致死:美国艾滋病政策的伦理成本转变》。
IF 1 3区 哲学 Q3 ETHICS Pub Date : 2025-07-07 DOI: 10.1111/dewb.70000
Udo Schüklenk
<p>It is difficult to offer a comprehensive account of the current US government's impact on global HIV/AIDS efforts. However, two particularly troubling developments merit urgent ethical scrutiny due to their immediate and long-term consequences for people living with HIV and for the future trajectory of the pandemic in the Global South.</p><p>At the core of both developments lies the United States’ unilateral decision to terminate support for PEPFAR (the President's Emergency Plan for AIDS Relief), a cornerstone of global HIV/AIDS funding for treatment, prevention, and research. Interestingly, PEPFAR was the brainchild of another Republican administration, albeit led by a different President, George W. Bush. In March 2025, the US Agency for International Development (USAID) was effectively dismantled by a newly appointed government efficiency czar, resulting in the abrupt cessation of financial support for these programmes. Simultaneously, the National Institutes of Health (NIH) implemented sweeping changes to its research funding policies, effectively ending its capacity to subcontract research to institutions in the Global South.</p><p>According to UNAIDS, the termination of PEPFAR could result in up to 4.2 million HIV-related deaths by 2029, assuming affected national governments are unable or unwilling to replace the lost funding.1 UNAIDS has also provided detailed country-level assessments of the impact of these cuts, which underscore the scale of the unfolding crisis.2</p><p>The second major consequence of these policy shifts is the widespread disruption—and in many cases, termination—of ongoing HIV vaccine and therapeutic research in the Global South. These projects, often midstream, were halted without prior warning, undermining years of scientific progress and infrastructure development.3</p><p>The harmful effects of these funding cuts then, in terms of life-years lost, are both immediate, in that people with HIV lose access to life-preserving drugs, as well as long-term, given that they undermine the development of a preventive vaccine. Glenda Gray, a globally leading HIV researcher in South Africa, lays out the immediate practical implications of the policy changes implemented by the US government. She writes, ‘basically you lose the knowledge or the value of understanding HIV prevention, HIV vaccines or therapeutics. We [<i>in South Africa</i>] have the infrastructure, we have the burden of disease, and we have the ability to answer these questions. And so it's going to take much longer to answer these questions than if you had South Africa there’.4 Gray's colleague, Francoise Venter, offers an equally sobering assessment: ‘We're watching the largest HIV treatment programme in the world unravelling in real time’.5</p><p>In Gray's considered view South Africa, a middle-income country, doesn't have the financial capacity to continue funding the existing projects and infrastructure. She puts it in these stark terms, ‘I'm going from ban
很难全面描述当前美国政府对全球艾滋病毒/艾滋病努力的影响。然而,有两个特别令人不安的事态发展值得紧急进行伦理审查,因为它们对艾滋病毒感染者和这一流行病在全球南方的未来发展轨迹产生了直接和长期的影响。这两个事态发展的核心是美国单方面决定终止对总统艾滋病紧急救援计划(PEPFAR)的支持,该计划是全球艾滋病毒/艾滋病治疗、预防和研究资金的基石。有趣的是,PEPFAR是另一届共和党政府的创意,尽管由另一位总统乔治·w·布什领导。2025年3月,美国国际开发署(USAID)实际上被新任命的政府效率沙皇解散,导致对这些项目的财政支持突然停止。与此同时,美国国立卫生研究院(NIH)对其研究资助政策进行了全面改革,有效地终止了将研究分包给南半球国家机构的能力。据联合国艾滋病规划署称,如果受影响的国家政府不能或不愿弥补损失的资金,到2029年,终止总统防治艾滋病紧急救援计划可能会导致多达420万人死于艾滋病联合国艾滋病规划署还提供了对这些削减的影响的详细国家一级评估,这强调了正在发生的危机的规模。2 .这些政策转变的第二个主要后果是,全球南方国家正在进行的艾滋病毒疫苗和治疗研究受到广泛干扰,在许多情况下甚至终止。这些项目往往处于中游,在没有事先警告的情况下被叫停,破坏了多年来的科学进步和基础设施建设。3 .因此,这些资金削减的有害影响,就失去的生命年数而言,既是立即的,因为艾滋病毒感染者无法获得维持生命的药物;又是长期的,因为它们破坏了预防性疫苗的研制。格伦达·格雷(Glenda Gray)是南非一位全球领先的艾滋病研究人员,她列出了美国政府实施的政策变化的直接实际影响。她写道,“基本上你失去了了解艾滋病毒预防、艾滋病毒疫苗或治疗方法的知识或价值。我们(在南非)有基础设施,我们有疾病负担,我们有能力回答这些问题。因此,回答这些问题要比回答南非的问题要长得多格雷的同事弗朗索瓦丝·文特尔(Francoise Venter)给出了一个同样发人深思的评估:“我们正在看着世界上最大的艾滋病治疗项目实时瓦解。”在格雷深思熟虑的观点中,南非是一个中等收入国家,没有财力继续为现有的项目和基础设施提供资金。她直截了当地说:“就我们的工作能力而言,我正从破产走向彻底破产。文特尔的预测同样可怕,他写道:“我们即将看到一波新的艾滋病毒感染、疾病和死亡浪潮,出生时感染艾滋病毒的儿童数量将达到创纪录的水平。”我们将看到我们的公立医院进一步不堪重负,我们在抗击结核病方面来之不易的胜利被逆转。在南非,非政府组织领导的诊所一夜之间关闭,据报道抗逆转录病毒药物短缺,数千名艾滋病毒项目的工作人员失去了工作。提供重要艾滋病服务的机构MatCH进入了商业救援。ANOVA也是一家主要的服务提供商,它裁减了2000名员工。负责监督艾滋病项目的TAC/Ritshidze裁减了75%的团队成员。由于资金冻结,23万剂预防艾滋病毒传播的长效注射药物没有发放如果这就是南非这个资源相对丰富的国家的情况,那么南半球较贫穷国家的前景就更加可怕了。即使人们认为美国政府的“美国优先”原则在道德上是站得住的,传染病传播的全球性质也会使这种孤立主义政策弄巧成拙。治疗中断增加了耐药艾滋病毒变体出现的可能性——这些变体不受国界限制。从纯粹务实、利己的角度来看,取消PEPFAR是一场高风险的赌博,赌的是全球和美国的国民健康。与资金有关的测试项目的崩溃进一步加剧了危机。在高患病率地区,被诊断并开始接受治疗的人数较少。这不仅危及他们的生命,而且还增加了进一步传播的风险,因为今天的有效治疗使个人几乎没有传染性。 值得注意的是,据报道,负责协调这些削减的个人是埃隆·马斯克,他是南非出生的亿万富翁,也是世界上最富有的人,他曾短暂领导过一个负责削减公共开支的政府机构。一个亿万富翁主持的削减计划对世界上最贫穷和最脆弱的群体造成了不成比例的伤害,这种讽刺意味很难被忽视。如果不反思这些发展的伦理层面,这篇社论将是不完整的。虽然道德争论是否会影响现任政府还值得怀疑,但它们对历史记录来说仍然至关重要。Christopher Lowry和我在几年前发表在《公共卫生伦理学》上的一篇论文中概述了全球卫生伦理学的两种范式是如何基于不同的道德原因支持这样一种观点,即美国对全球南方负有卫生援助义务(其他国家,包括欧洲国家也是如此)人道主义模式支持这样一种观点,即富裕国家有道德义务防止可避免的人类苦难,因为如果代价不是高得不合理的话,这样做在道德上是可取的。这种政治模式为这种观点辩护,认为这种全球卫生援助在道义上是有义务的,因为它认为全球南方国家最贫穷的公民是脆弱的,因为国与国之间的有害行为使全球北方国家受益,而损害了全球南方国家的公民。无论以哪一种标准衡量,当前美国政府的政策都构成了严重的道德失败。如果不改变,它们将导致数以百万计的可预防的死亡——主要是在全球南方,但最终也会在全球北方,因为艾滋病毒继续不受控制地传播。文特尔对南非局势的生动描述表明,时间是至关重要的。削减的速度和力度几乎没有留下缓解的余地。这场正在上演的灾难要求其他高收入国家和有能力采取行动的私人资助者采取协调一致的应对措施。道德和实际的利害关系不能再高了。全球北方的资助者撤回对全球南方人民受益的项目的资助,不应被视为道德失败的自动迹象。例如,人们可以对格雷的说法提出异议,他认为一个像南非这样相对富裕的国家,确实无法为其感染艾滋病毒的公民承担更大的经济责任也许应该,而且应该向政府施加更大的压力,要求其提供必要的资金。人们也可能会质疑,为什么其他富裕国家(尤其是欧洲国家)不愿意挺身而出提供帮助。然而,尽管如此,如果考虑这种单方面的退出决定,应作出合理的努力,尽量减少由此造成的损害。这就需要充分提前通知受影响国家和社区的地方当局,使其能够实施缓解措施。在没有事先警告的情况下采取本社论所述的行动,表明对全球南方人民缺乏尊重,对那些因撤出重要保健服务而直接受影响的人所受的伤害漠不关心,令人担忧。最后,在试验中途突然撤回研究经费也引发了关于国际研究伦理治理的严重问题。也许是时候让伦理审查委员会重新审视这些资金的发放和撤回条件了。不应该允许批准机构或当时的政治权力改变政策前景的外来条件结束原本正在成功进行的临床试验。作者声明无利益冲突。
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引用次数: 0
Anaesthesia Waste Gases and Bioethics: Balancing Patient Care, Environmental Responsibility, and Occupational Safety. 麻醉废气和生物伦理:平衡病人护理、环境责任和职业安全。
IF 0.9 3区 哲学 Q3 ETHICS Pub Date : 2025-06-15 DOI: 10.1111/dewb.12489
Shibu Sasidharan, Harpreet Dhillon

Anaesthesia waste gases (AWGs) represent a significant yet often overlooked contributor to healthcare's environmental footprint, with implications extending beyond ecological concerns to encompass occupational hazards and complex ethical considerations. This article examines the intersection of AWGs and bioethics through the framework of environmental stewardship, occupational health principles, patient-centered care, and distributive justice. Contemporary volatile anaesthetics possess global warming potentials thousands of times greater than carbon dioxide, while implicated occupational exposures raise concerns about reproductive health and neurological function among healthcare workers. The bioethical paradigms of principalism-encompassing nonmaleficence, beneficence, autonomy, and justice-and environmental ethics provide structured approaches to addressing these multifaceted challenges. This review synthesizes current evidence regarding AWGs' environmental and occupational impacts, evaluates emerging mitigation strategies, and proposes an integrated ethical framework to guide clinical practice, institutional policy, and professional standards in anaesthesiology.

麻醉废气(awg)是医疗保健环境足迹的重要贡献者,但往往被忽视,其影响超出了生态问题,包括职业危害和复杂的道德考虑。本文通过环境管理、职业健康原则、以患者为中心的护理和分配正义的框架,探讨了AWGs和生物伦理学的交集。当代挥发性麻醉剂具有比二氧化碳大数千倍的全球变暖潜能值,而涉及的职业暴露引起了对卫生保健工作者生殖健康和神经功能的关注。原则主义的生物伦理范式——包括无害、仁慈、自治和正义——以及环境伦理为解决这些多方面的挑战提供了结构化的方法。本综述综合了AWGs对环境和职业影响的现有证据,评估了新兴的缓解策略,并提出了一个综合的道德框架,以指导临床实践、机构政策和麻醉学专业标准。
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引用次数: 0
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Developing World Bioethics
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