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Fatigue strength analysis of a new left atrial appendage occluder at different release scales. 新型左心房阑尾封堵器在不同释放尺度下的疲劳强度分析
IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2024-09-17 DOI: 10.1080/10255842.2024.2405084
Yanlong Chen,Haiquan Feng,Juan Su
Owing to its low incidence, small trauma, fast recovery, and high efficiency, left atrial appendage occlusion has become a new strategy for preventing stroke caused by atrial fibrillation. Due to a lack of relevant research information on this emerging technology, the effectiveness, stability, or related complications of occluders are mostly observed from a clinical perspective. However, there are fewer studies on the mechanical properties and safety of these occluders. In this study, a new left atrial appendage occluder is proposed, and a complete numerical simulation analysis framework is established through the finite element method to simulate the actual implantation and service process of the left atrial appendage occluder. Besides, the influence of the structural size and release scale of the occluder on its support performance, occluding effect, and safety is also explored. The results demonstrate that the structural size and release scale exert a significant impact on the support performance, occluding effect, and safety of the occluder. The structural optimization of the occluder contributes to enhancing its mechanical performance, thus ensuring its stability and effectiveness after implantation. Overall, these efforts may lay a scientific foundation for the structural optimization, safety evaluation, and effectiveness prediction of the occluder. Furthermore, these findings also provide effective reference for the application of numerical simulation technology in the research on the left atrial appendage occlusion.
左心房阑尾封堵术因其发病率低、创伤小、恢复快、效率高等特点,已成为预防心房颤动引起中风的一种新策略。由于缺乏对这一新兴技术的相关研究资料,人们大多从临床角度观察封堵器的有效性、稳定性或相关并发症。然而,关于这些封堵器的机械性能和安全性的研究较少。本研究提出了一种新型的左房阑尾封堵器,并通过有限元法建立了完整的数值模拟分析框架,模拟左房阑尾封堵器的实际植入和使用过程。此外,还探讨了封堵器的结构尺寸和释放尺度对其支撑性能、封堵效果和安全性的影响。结果表明,结构尺寸和释放尺度对闭塞器的支撑性能、闭塞效果和安全性有显著影响。闭塞器结构的优化有助于提高其机械性能,从而确保其植入后的稳定性和有效性。总之,这些工作可为闭塞器的结构优化、安全性评估和有效性预测奠定科学基础。此外,这些研究结果也为数值模拟技术在左房阑尾闭塞研究中的应用提供了有效参考。
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引用次数: 0
Joint multi-feature extraction and transfer learning in motor imagery brain computer interface 运动图像脑机接口中的联合多特征提取和迁移学习
IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2024-09-17 DOI: 10.1080/10255842.2024.2404541
Miao Cai, Jie Hong
Motor imagery brain computer interface (BCI) systems are considered one of the most crucial paradigms and have received extensive attention from researchers worldwide. However, the non-stationary f...
运动图像脑机接口(BCI)系统被认为是最重要的范例之一,受到全世界研究人员的广泛关注。然而,运动想象的非稳态...
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引用次数: 0
The impact of toe spring and foot strike angle on forefoot running biomechanics: a finite element analysis. 脚趾弹力和脚掌击球角度对前脚掌跑步生物力学的影响:有限元分析。
IF 1.7 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2024-09-16 DOI: 10.1080/10255842.2024.2402860
Fengping Li, Dong Sun, Chengyuan Zhu, Qiaolin Zhang, Yang Song, Xuanzhen Cen, Yining Xu, Zhiyi Zheng, Yaodong Gu

The surge in popularity of running has led to a multitude of designs in running shoe technology, notably, there is an increasing trend in toe spring elevation. However, the impact of this design on foot structures during running remains an essential exploration. To investigate the effects of toe spring on the foot during forefoot running, we employed finite element simulation to create two sole models with different toe spring heights (6.5 cm and 8 cm) and ground contact angles (5°, 10°, and 15°). We established and validated two foot-shoe coupling models and compared stress variations in metatarsal bones and the big toe under identical loading and environmental conditions. Higher toe spring resulted in lower peak stress and reduced stress concentration in metatarsal bones. The fourth and fifth metatarsals exhibited increasing stress trends with ground contact angle, with the fifth metatarsal experiencing the most significant stress concentration. In the case of low toe spring, stress on the fifth metatarsal increased from 15.917 MPa (5°) to 27.791 MPa (15°), indicating a rise of 11.874 MPa. Conversely, the first metatarsal showed lower stress, indicating relative safety but reduced functional significance. Moreover, higher toe spring running shoes exerted less pressure on the big toe, with an increasing trend in stress on the big toe with an increase in ground contact angle. Shoes with a higher toe spring design result in reduced pressure on the big toe. Therefore, it is advisable to avoid landing angles greater than 15° to prevent stress fractures resulting from repetitive loading.

随着跑步运动的普及,跑鞋技术也出现了许多新的设计,尤其是鞋头弹簧的升高趋势日益明显。然而,这种设计在跑步过程中对足部结构的影响仍然是一项重要的探索。为了研究前脚掌跑步时脚趾弹簧对足部的影响,我们采用有限元模拟创建了两个具有不同脚趾弹簧高度(6.5 厘米和 8 厘米)和地面接触角(5°、10° 和 15°)的鞋底模型。我们建立并验证了两种足鞋耦合模型,并比较了在相同负载和环境条件下跖骨和大脚趾的应力变化。脚趾弹簧越大,跖骨的峰值应力越低,应力集中程度越小。第四和第五跖骨的应力随地面接触角的增加而呈上升趋势,其中第五跖骨的应力集中最为明显。在脚趾弹簧较低的情况下,第五跖骨的应力从 15.917 兆帕(5°)增加到 27.791 兆帕(15°),增加了 11.874 兆帕。相反,第一跖骨的应力较低,表明相对安全,但功能意义降低。此外,鞋头弹簧较高的跑鞋对大脚趾施加的压力较小,随着地面接触角的增加,大脚趾的应力呈上升趋势。鞋头弹簧设计较高的跑鞋对大脚趾的压力较小。因此,建议避免着地角度大于 15°,以防止重复负荷造成应力性骨折。
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引用次数: 0
Finite element analysis of three internal fixations for the posteromedial split fracture fragment in tibial plateau fractures 胫骨平台骨折后内侧劈裂骨折片三种内固定的有限元分析
IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2024-09-16 DOI: 10.1080/10255842.2024.2399036
Wupeng Zhang, Cheng Xu, Zhengfeng Jia, Daofeng Wang, Weilu Gao, Jiantao Li, Licheng Zhang, Peifu Tang
Posteromedial tibial plateau fracture is one of the most challenging traumatic fractures. We aimed to compare and explain the biomechanical advantages and disadvantages of different internal fixati...
胫骨平台后内侧骨折是最具挑战性的创伤性骨折之一。我们的目的是比较和解释不同内固定方法在生物力学上的优缺点。
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引用次数: 0
Comment on permeability conditions in finite element simulation of bone fracture healing 关于骨骨折愈合有限元模拟中的渗透性条件的评论
IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2024-09-14 DOI: 10.1080/10255842.2024.2402878
Agnieszka Sabik
The most popular model of the bone healing considers the fracture callus as poroelastic medium. As such it requires an assumption of the callus’ external permeability. In this work a systematic stu...
最流行的骨愈合模型将骨折茧视为孔弹性介质。因此,它需要假设胼胝体的外部渗透性。在这项工作中,系统地研究了...
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引用次数: 0
A zero precision loss framework for EEG channel selection: enhancing efficiency and maintaining interpretability 用于脑电图信道选择的零精度损失框架:提高效率并保持可解释性
IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2024-09-13 DOI: 10.1080/10255842.2024.2401918
Lu Wang, Junkongshuai Wang, Haolong Su, Xueze Zhang, Lihua Zhang, Xiaoyang Kang
The brain-computer interface (BCI) systems based on motor imagery typically rely on a large number of electrode channels to acquire information. The rational selection of electroencephalography (EE...
基于运动图像的脑机接口(BCI)系统通常依靠大量的电极通道来获取信息。如何合理选择脑电图(EE)通道?
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引用次数: 0
A quasilinear hyperbolic one-dimensional model of the lymph flow through a lymphangion with valve dynamics and a contractile wall 带有瓣膜动力学和收缩壁的淋巴管淋巴流的准线性双曲一维模型
IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2024-09-11 DOI: 10.1080/10255842.2024.2399769
Alberto Girelli
This paper presents a one-dimensional model that describes fluid flow in lymphangions, the segments of lymphatic vessels between valves, using quasilinear hyperbolic systems. The model incorporates...
本文提出了一个利用准线性双曲系统描述淋巴管(淋巴管在瓣膜之间的一段)中流体流动的一维模型。该模型包含...
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引用次数: 0
Fracture risk prediction in diabetes patients based on Lasso feature selection and Machine Learning. 基于拉索特征选择和机器学习的糖尿病患者骨折风险预测
IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2024-09-11 DOI: 10.1080/10255842.2024.2400325
Yu Shi,Junhua Fang,Jiayi Li,Kaiwen Yu,Jingbo Zhu,Yan Lu
Fracture risk among individuals with diabetes poses significant clinical challenges due to the multifaceted relationship between diabetes and bone health. Diabetes not only affects bone density but also alters bone quality and structure, thereby increases the susceptibility to fractures. Given the rising prevalence of diabetes worldwide and its associated complications, accurate prediction of fracture risk in diabetic individuals has emerged as a pressing clinical need. This study aims to investigate the factors influencing fracture risk among diabetic patients. We propose a framework that combines Lasso feature selection with eight classification algorithms. Initially, Lasso regression is employed to select 24 significant features. Subsequently, we utilize grid search and 5-fold cross-validation to train and tune the selected classification algorithms, including KNN, Naive Bayes, Decision Tree, Random Forest, AdaBoost, XGBoost, Multi-layer Perceptron (MLP), and Support Vector Machine (SVM). Among models trained using these important features, Random Forest exhibits the highest performance with a predictive accuracy of 93.87%. Comparative analysis across all features, important features, and remaining features demonstrate the crucial role of features selected by Lasso regression in predicting fracture risk among diabetic patients. Besides, by using a feature importance ranking algorithm, we find several features that hold significant reference values for predicting early bone fracture risk in diabetic individuals.
由于糖尿病与骨骼健康之间的多方面关系,糖尿病患者的骨折风险给临床带来了巨大挑战。糖尿病不仅会影响骨密度,还会改变骨质和结构,从而增加骨折的易感性。鉴于糖尿病及其相关并发症在全球的发病率不断上升,准确预测糖尿病患者的骨折风险已成为一项迫切的临床需求。本研究旨在调查影响糖尿病患者骨折风险的因素。我们提出了一个将 Lasso 特征选择与八种分类算法相结合的框架。首先,采用 Lasso 回归来选择 24 个重要特征。随后,我们利用网格搜索和 5 倍交叉验证来训练和调整所选的分类算法,包括 KNN、Naive Bayes、决策树、随机森林、AdaBoost、XGBoost、多层感知器(MLP)和支持向量机(SVM)。在使用这些重要特征训练的模型中,随机森林的性能最高,预测准确率达到 93.87%。对所有特征、重要特征和其余特征的比较分析表明,Lasso 回归所选择的特征在预测糖尿病患者骨折风险方面起着至关重要的作用。此外,通过使用特征重要性排序算法,我们还发现了几个对预测糖尿病患者早期骨折风险具有重要参考价值的特征。
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引用次数: 0
Biomechanical model of minimally invasive hallux valgus surgery 微创外翻手术的生物力学模型
IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2024-09-10 DOI: 10.1080/10255842.2024.2400321
Yueyang Zhang, Yibo Ren, Jiateng Pan, Zihe Liu, Wanan Xiao, Yu Zhan
Hallux valgus is a common foot deformity characterized by outward tilting and twisting of the big toe, often accompanied by a medial prominence at the base. Minimally invasive surgical techniques a...
拇外翻是一种常见的足部畸形,其特征是大脚趾向外倾斜和扭曲,通常伴有脚底内侧突出。微创手术技术是治疗拇指外翻的最佳方法。
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引用次数: 0
Finite element analysis and surrogate-optimized design of a nature-inspired auxetic stent. 受自然启发的辅助支架的有限元分析和代用优化设计。
IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Pub Date : 2024-09-10 DOI: 10.1080/10255842.2024.2399018
Y W Teong,K B Mustapha,Morufu Olusola Ibitoye
Prior studies have revealed that the structural design of stents is critical to reducing some of the alarming post-operative complications associated with stent-related intervention. However, the technical search for stents that guarantee robustness against stent-induced post-intervention complications remains an open problem. Along this objective, this study investigates a re-entrant auxetic stent's structural response and performance optimizations. In pursuit of the goal, a nonlinear finite element analysis (FEA) is employed to uncover metrics characterizing the auxetic stent's mechanical behavior. Subsequently, the non-dominated sorting genetic algorithm (NSGA-II) is implemented to simultaneously minimize the stent's von Mises stress and the elastic radial recoil (ERR). Results from the FEA revealed a tight connection between the stent's response and the features of the base auxetic building block (the rib length, strut width, and the re-entrant angle). It is observed that the auxetic stent exhibits a much lower ERR. Besides, larger values of its rib length and re-entrant angle are noticed to favor smaller von Mises stress. The Pareto-optimal front from the NSGA-II-based optimization scheme revealed a sharp trade-off in the simultaneous minimization of the von Mises stress and the ERR. Moreover, an optimal combination of the auxetic unit cell's geometric parameters is found to yield a much lower maximum von Mises stress of ≈403 MPa and ERR of ≈0.4%.
先前的研究表明,支架的结构设计对于减少与支架相关的介入治疗引起的一些令人担忧的术后并发症至关重要。然而,如何从技术上寻求支架,以确保其坚固耐用,防止支架引发介入术后并发症,仍是一个有待解决的问题。根据这一目标,本研究对再入式辅助支架的结构响应和性能优化进行了研究。为了实现这一目标,我们采用了非线性有限元分析(FEA)来揭示辅助支架机械行为的特征指标。随后,采用非支配排序遗传算法(NSGA-II)同时最小化支架的冯米塞斯应力和弹性径向反冲(ERR)。有限元分析的结果表明,支架的响应与基础辅助构件的特征(肋骨长度、支柱宽度和再入角等)密切相关。可以看出,辅助支架的等效误差要小得多。此外,肋长和再入角值越大,von Mises 应力越小。基于 NSGA-II 的优化方案得出的帕累托最优前沿显示,在同时最小化 von Mises 应力和 ERR 的过程中,存在着急剧的权衡。此外,还发现辅助单元几何参数的最佳组合可产生更低的最大 von Mises 应力(≈403 兆帕)和ERR(≈0.4%)。
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Computer Methods in Biomechanics and Biomedical Engineering
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