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Is computer-assisted surgery in total knee arthroplasty as accurate as it can be? 全膝关节置换术的计算机辅助手术是否尽可能准确?
Q Medicine Pub Date : 2012-01-01 Epub Date: 2012-06-08 DOI: 10.3109/10929088.2012.691178
David R Lionberger, Catherine L Crocker, Mohammad H Rahbar

Three hundred and eighty computer-assisted total knee arthroplasty cases were reviewed for accuracy of mechanical alignment. The 331 patients in the first set, designated Group A, showed a consistent valgus error of 1° from neutral alignment. It was hypothesized that a manual 1° varus correction during femur resection would yield a significantly greater level of accuracy in the second set of 49 patients, designated Group B. A mechanical alignment of ±3° was achieved in 91% of the uncalibrated Group A patients, which was significantly lower (p = 0.035) than the rate of 98% achieved in the calibrated Group B. Further statistical analysis of the data showed the time expenditure was not significantly changed once a new target value was recalibrated. By quantifying mean errors of measures at an early timeframe, enhanced accuracy in CAS can be achieved.

本文回顾了380例计算机辅助全膝关节置换术的机械对齐精度。第一组331例患者,被称为A组,显示出与中性对齐一致的1°外翻误差。假设在第二组49例患者(b组)中,在股骨切除术期间手动1°内翻矫正会产生更高的准确性。未校准的a组患者中,91%的患者实现了±3°的机械对准。显著低于经校准的b组98%的成功率(p = 0.035)。对数据的进一步统计分析表明,重新校准新的目标值后,时间支出没有显著变化。通过量化早期测量的平均误差,可以提高CAS的精度。
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引用次数: 0
Computer guidance system for single-incision bimanual robotic surgery. 单切口手工机器人手术的计算机引导系统。
Q Medicine Pub Date : 2012-01-01 Epub Date: 2012-06-11 DOI: 10.3109/10929088.2012.692168
Marina Carbone, Giuseppe Turini, Gianluigi Petroni, Marta Niccolini, Arianna Menciassi, Mauro Ferrari, Franco Mosca, Vincenzo Ferrari

The evolution of surgical robotics is following the progress of developments in Minimally Invasive Surgery (MIS), which is moving towards Single-Incision Laparoscopic Surgery (SILS) procedures. The complexity of these techniques has favored the introduction of robotic surgical systems. New bimanual robots, which are completely inserted into the patient's body, have been proposed in order to enhance the surgical gesture in SILS procedures. However, the limited laparoscopic view and the focus on the end-effectors, together with the use of complex robotic devices inside the patient's abdomen, may lead to unexpected collisions, e.g., between the surrounding anatomical organs not involved in the intervention and the surgical robot. This paper describes a computer guidance system, based on patient-specific data, designed to provide intraoperative navigation and assistance in SILS robotic interventions. The navigator has been tested in simulations of some of the surgical tasks involved in a cholecystectomy, using a synthetic anthropomorphic mannequin. The results demonstrate the usability and efficacy of the navigation system, underlining the importance of avoiding unwanted collisions between the robot arms and critical organs. The proposed computer guidance software is able to integrate any bimanual surgical robot design.

手术机器人的发展是随着微创手术(MIS)的发展而发展的,它正朝着单切口腹腔镜手术(SILS)的方向发展。这些技术的复杂性有利于引入机器人手术系统。为了提高SILS手术过程中的手术姿态,已经提出了一种完全插入患者体内的新型双手机器人。然而,有限的腹腔镜视野和对末端执行器的关注,以及在患者腹部使用复杂的机器人装置,可能会导致意外的碰撞,例如,周围未参与干预的解剖器官与手术机器人之间的碰撞。本文描述了一种基于患者特定数据的计算机引导系统,旨在为SILS机器人干预提供术中导航和辅助。导航仪已经在模拟一些涉及胆囊切除术的手术任务中进行了测试,使用的是合成的拟人化人体模型。结果证明了导航系统的可用性和有效性,强调了避免机器人手臂与关键器官之间不必要碰撞的重要性。所提出的计算机引导软件能够集成任何手工手术机器人的设计。
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引用次数: 6
Three-dimensional multimodal image non-rigid registration and fusion in a High Intensity Focused Ultrasound system. 三维多模态图像在高强度聚焦超声系统中的非刚性配准与融合。
Q Medicine Pub Date : 2012-01-01 DOI: 10.3109/10929088.2011.637235
Xuesong Lu, Shiteng Suo, Haihua Liu, Su Zhang

High Intensity Focused Ultrasound (HIFU) has been successfully applied in tumor therapy. For a successful HIFU therapy, it is crucial to localize the tumor region accurately. In this paper, we present a semi-automatic non-rigid registration method for implementing image guided surgery navigation and localization by matching pre-operative CT/MR images and intra-operative ultrasound images. The global motion of the target is modeled by an affine transformation, while the local deformation of the target is described by Free-Form Deformation (FFD) based on B-splines. The results of our experiments on simulated and real data show that the non-rigid registration method based on HPV interpolation (partial volume based on the Hanning windowed sinc function) is effective at restraining local extrema and improves the accuracy of registration results. A preliminary clinical validation of the use of the non-rigid registration method in image guided localization of a HIFU system is also reported.

高强度聚焦超声(HIFU)已成功应用于肿瘤治疗。对于成功的HIFU治疗,准确定位肿瘤区域是至关重要的。本文提出了一种半自动非刚性配准方法,通过匹配术前CT/MR图像和术中超声图像,实现图像引导手术导航和定位。目标的全局运动采用仿射变换建模,目标的局部变形采用基于b样条的自由形式变形(FFD)描述。在仿真和实际数据上的实验结果表明,基于HPV插值的非刚性配准方法(基于Hanning窗口sinc函数的部分体积)能够有效抑制局部极值,提高配准结果的精度。非刚性配准方法在HIFU系统的图像引导定位的初步临床验证也被报道。
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引用次数: 2
Effect of registration mode on neuronavigation precision: an exploration of the role of random error. 配准方式对神经导航精度的影响:随机误差作用的探讨。
Q Medicine Pub Date : 2012-01-01 Epub Date: 2012-06-08 DOI: 10.3109/10929088.2012.691992
Asem Salma, Orphée Makiese, Steffen Sammet, Mario Ammirati

The aim of this paper is to analyze the variations in registration accuracy for computer-assisted surgical navigation using three different modes of registration, in order to explore the behavior of random error, and to highlight the precision of neuronavigation as a concept distinct from accuracy. The operational accuracy of three different registration modes (bone fiducials, scalp adhesive fiducials and an auto-registration mask) was evaluated in a total of 20 fresh cadaveric heads. The precision of the neuronavigation system was then assessed by evaluating the variation in the accuracy measurements associated with each registration mode. The coefficient of variation was employed to quantify the degree of variation in the attained accuracy using the following formula: Coefficient of variation = standard deviation/mean * 100. For external targets, the precision of the neuronavigation system was greatest with mask registration (43.75 and 51.41 for anterior and posterior external targets, respectively) and lowest with bone registration (65.30 and 67.17 for anterior and posterior external targets, respectively). For internal targets, the precision of the neuronavigation system was greatest with bone registration (47.69 and 42.6 for anterior and posterior internal targets, respectively) and lowest with mask registration (62.9 and 58.67 for anterior and posterior internal targets, respectively). The precision (reproducibility) of the neuronavigation system is another important quantity besides accuracy that characterizes the performance of the system. Understanding both of these quantities for a given registration mode enhances the use of a neuronavigation system in neurosurgery.

本文的目的是分析使用三种不同的配准模式的计算机辅助手术导航的配准精度的变化,以探讨随机误差的行为,并突出神经导航的精度作为一个不同于精度的概念。在总共20个新鲜尸体头部中评估了三种不同配准模式(骨基准、头皮黏附基准和自动配准面罩)的操作精度。然后通过评估与每种注册模式相关的精度测量的变化来评估神经导航系统的精度。变异系数用于量化获得精度的变异程度,公式如下:变异系数=标准差/平均值* 100。对于外部目标,面罩配准时神经导航系统的精度最高(前后外部目标分别为43.75和51.41),骨配准时精度最低(前后外部目标分别为65.30和67.17)。对于内靶,骨配准时神经导航系统的精度最高(前后路内靶分别为47.69和42.6),而面罩配准时精度最低(前后路内靶分别为62.9和58.67)。神经导航系统的精度(再现性)是除精度外表征系统性能的另一个重要指标。对于给定的配准模式,理解这两个量可以增强神经导航系统在神经外科中的应用。
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引用次数: 11
Towards modeling tumor motion in the deflated lung for minimally invasive ablative procedures. 在微创消融手术中模拟肺内肿瘤运动的研究。
Q Medicine Pub Date : 2012-01-01 DOI: 10.3109/10929088.2012.708788
Ali Sadeghi-Naini, Zahra Shirzadi, Abbas Samani

A computational model is proposed to demonstrate the feasibility of characterizing the motion of lung tumors caused by respiratory diaphragm forces using a tissue biomechanics approach. Compensating for such motion is very important for developing effective systems of minimally invasive tumor ablative procedures, e.g., Low Dose Rate (LDR) lung brachytherapy. To minimize the effects of respiratory motion, the target lung is almost completely deflated before starting such procedures. However, a significant amount of motion persists in the target lung due to the diaphragm contact forces required for the other lung's respiration. In this study, a model pipeline was developed which inputs a pre-operative 4D-CT image sequence of the lung to output the predicted 3D motion trajectory of the tumor over the respiratory cycle. A finite element method was used in this pipeline to model the lung tissue deformation in order to predict the tumor motion. Experiments were conducted on an ex vivo porcine lung to demonstrate the performance and assess the accuracy of the proposed pipeline. The resultant tumor motion trajectory obtained from the biomechanical model of the lung was compared to the experimental trajectory obtained from CT imaging. Results were promising, suggesting that tissue mechanics-based modeling can be employed for effective characterization of lung tumor respiratory motion to improve accuracy in lung tumor ablative procedures.

提出了一个计算模型,以证明利用组织生物力学方法表征由呼吸隔膜力引起的肺肿瘤运动的可行性。补偿这种运动对于开发有效的微创肿瘤消融手术系统非常重要,例如低剂量率(LDR)肺近距离放射治疗。为了尽量减少呼吸运动的影响,靶肺在开始这种手术之前几乎完全放气。然而,由于另一个肺的呼吸所需要的隔膜接触力,在目标肺中持续有大量的运动。在这项研究中,开发了一个模型管道,它输入肺的术前4D-CT图像序列,以输出预测的肿瘤在呼吸周期内的3D运动轨迹。采用有限元法对肺组织变形进行建模,以预测肿瘤的运动。实验在离体猪肺上进行,以证明该管道的性能并评估其准确性。将肺生物力学模型得到的肿瘤运动轨迹与CT成像得到的实验轨迹进行比较。结果很有希望,表明基于组织力学的建模可用于有效表征肺肿瘤呼吸运动,以提高肺肿瘤消融手术的准确性。
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引用次数: 2
Sensor fusion for laparoscopic surgery skill acquisition. 传感器融合在腹腔镜手术技能获取中的应用。
Q Medicine Pub Date : 2012-01-01 DOI: 10.3109/10929088.2012.727641
Fraser Anderson, Daniel W Birch, Pierre Boulanger, Walter F Bischof

Surgical techniques are becoming more complex and require substantial training to master. The development of automated, objective methods to analyze and evaluate surgical skill is necessary to provide trainees with reliable and accurate feedback during their training programs. We present a system to capture, visualize, and analyze the movements of a laparoscopic surgeon for the purposes of skill evaluation. The system records the upper body movement of the surgeon, the position, and orientation of the instruments, and the force and torque applied to the instruments. An empirical study was conducted using the system to record the performances of a number of surgeons with a wide range of skill. The study validated the usefulness of the system, and demonstrated the accuracy of the measurements.

外科技术正变得越来越复杂,需要大量的训练才能掌握。开发自动化、客观的方法来分析和评估手术技能是必要的,以便在培训计划中为受训者提供可靠和准确的反馈。我们提出了一个系统来捕捉、可视化和分析腹腔镜外科医生的动作,以进行技能评估。系统记录外科医生上半身的运动,器械的位置和方向,以及施加在器械上的力和扭矩。一项实证研究使用该系统来记录一些具有广泛技能的外科医生的表现。该研究验证了该系统的实用性,并证明了测量的准确性。
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引用次数: 13
Patient-specific surgical simulator for the pre-operative planning of single-incision laparoscopic surgery with bimanual robots. 用于单切口腹腔镜手术术前规划的患者特异性手术模拟器与双手机器人。
Q Medicine Pub Date : 2012-01-01 DOI: 10.3109/10929088.2012.672595
Giuseppe Turini, Andrea Moglia, Vincenzo Ferrari, Mauro Ferrari, Franco Mosca

Introduction: The trend of surgical robotics is to follow the evolution of laparoscopy, which is now moving towards single-incision laparoscopic surgery. The main drawback of this approach is the limited maneuverability of the surgical tools. Promising solutions to improve the surgeon's dexterity are based on bimanual robots. However, since both robot arms are completely inserted into the patient's body, issues related to possible unwanted collisions with structures adjacent to the target organ may arise.

Materials and methods: This paper presents a simulator based on patient-specific data for the positioning and workspace evaluation of bimanual surgical robots in the pre-operative planning of single-incision laparoscopic surgery.

Results: The simulator, designed for the pre-operative planning of robotic laparoscopic interventions, was tested by five expert surgeons who evaluated its main functionalities and provided an overall rating for the system.

Discussion: The proposed system demonstrated good performance and usability, and was designed to integrate both present and future bimanual surgical robots.

手术机器人的发展趋势是跟随腹腔镜技术的发展,目前正在向单切口腹腔镜手术发展。这种方法的主要缺点是手术工具的可操作性有限。有希望提高外科医生灵活性的解决方案是基于双手机器人。然而,由于两个机械臂都完全插入患者体内,可能会出现与目标器官附近结构发生不必要碰撞的问题。材料与方法:本文提出了一种基于患者特异性数据的模拟器,用于单切口腹腔镜手术术前规划中手动手术机器人的定位和工作空间评估。结果:该模拟器是为机器人腹腔镜干预的术前规划而设计的,由五位专家外科医生进行了测试,他们评估了其主要功能并提供了系统的总体评级。讨论:提出的系统表现出良好的性能和可用性,并被设计用于集成当前和未来的双手手术机器人。
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引用次数: 8
Hinged external fixator placement at the elbow: navigated versus conventional technique. 肘部铰接外固定架放置:导航与常规技术比较。
Q Medicine Pub Date : 2012-01-01 DOI: 10.3109/10929088.2012.722683
C C Egidy, D Fufa, D Kendoff, A Daluiski

Introduction: During the application of a hinged external elbow fixator, exact placement of the central pin remains difficult. Proper placement often necessitates multiple drilling attempts and fluoroscopic localization, which can be time consuming. We hypothesized that use of computerized navigation would enable a more precise placement of the central axis pin and would reduce the total number of drilling attempts.

Materials and methods: Twelve elbow models incorporating soft tissue coverage were used in this study. First, the optimal placement trajectory (OPJ) of the axis pin was defined in the anterior-posterior (AP) and lateral planes of the elbow. Six elbows were used with the navigation system and the axis pin was inserted in combination with a conventional fluoroscopy system under constant two-dimensional guidance from the virtual images. The pins for the remaining six elbow specimens were implanted conventionally under fluoroscopic guidance. The distances and angular deviations from the OPJ position were measured, and the results for the conventional placement and computer navigation groups were compared. To determine the definitive axis pin placement, a CT scan of each elbow with 1-mm slice thickness was used and the results were measured based on the defined optimal pin placement. AP plane angulations and lateral plane distances were calculated in relation to the optimal insertion trajectory for each specimen. Finally, we counted the overall number of drilling attempts needed to find the optimal position for the axis pin.

Results: For the AP angulations, of the six elbows implanted using the conventional technique, half (n=3) had deviations of ≥20° from the optimal axis. In contrast, in the navigated group, all cases (n=6) were within 20° of the optimal axis in the AP plane. The mean AP angulation deviation in the conventional group was 20.5°, compared to 15° in the navigation group (p=0.077). For the lateral distances, the mean distance from the drilling point to the point of optimal placement was 3.83 mm in the conventional group, versus 1.83 mm in the navigation group (p=0.042). For all navigated cases, only one drilling attempt was necessary to achieve the desired position of the axial pin.

Conclusion: Compared with the conventional method of axis pin placement for an elbow fixator, two-dimensional navigation allows a reduction in the number of drilling attempts required. Furthermore, the accuracy in terms of AP angulation and lateral distance from a defined optimal placement is better when compared to that obtained with the conventional technique.

简介:在应用铰链式肘外固定器时,中心销的精确定位仍然很困难。适当的放置通常需要多次钻孔尝试和透视定位,这可能是耗时的。我们假设使用计算机导航可以更精确地定位中心轴销,并减少钻井尝试的总次数。材料和方法:本研究采用12个肘关节软组织覆盖模型。首先,在肘关节的前后(AP)和外侧平面确定轴钉的最佳放置轨迹(OPJ)。导航系统使用六个肘部,在虚拟图像的恒定二维引导下,将轴销与常规透视系统结合插入。其余6个肘关节标本的针在透视引导下常规植入。测量与OPJ位置的距离和角度偏差,并比较常规放置组和计算机导航组的结果。为了确定最终的轴向销钉放置位置,对每个肘关节进行1毫米厚度的CT扫描,并根据确定的最佳销钉放置位置测量结果。根据每个标本的最佳插入轨迹计算AP平面角度和侧向平面距离。最后,我们计算了为轴销找到最佳位置所需的钻孔次数。结果:对于AP角度,使用常规技术植入的6个肘关节中,有一半(n=3)的肘关节偏离最佳轴≥20°。相比之下,在导航组中,所有病例(n=6)都在AP平面最佳轴的20°范围内。常规组AP角度偏差均值为20.5°,导航组为15°(p=0.077)。对于横向距离,常规组从钻孔点到最佳放置点的平均距离为3.83 mm,而导航组为1.83 mm (p=0.042)。对于所有导航情况,只需一次钻井尝试即可达到轴向销的理想位置。结论:与传统的肘关节固定器轴向销钉放置方法相比,二维导航可以减少所需的钻孔次数。此外,与传统技术相比,在AP成角和从定义的最佳位置获得的横向距离方面的准确性更好。
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引用次数: 4
Image guided surgery of the lateral skull base: testing a new dental splint registration device. 图像引导手术的侧颅底:测试一种新的牙夹板配准装置。
Q Medicine Pub Date : 2012-01-01 DOI: 10.3109/10929088.2011.632783
Georg J Ledderose, Hjalmar Hagedorn, Kathrin Spiegl, Andreas Leunig, Klaus Stelter

Objective: The widespread use of image guided surgery in the frontolateral skull base region has been limited by the need for a reliable and non-invasive registration procedure that provides sub-millimetric accuracy. We developed and validated preclinically a non-invasive, easy-to-use registration device based on a dental splint with a laterally mounted fiducial carrier.

Methods: Repeated accuracy measurements were performed on six titanium target fiducials which were screwed into the lateral skull base region of a cadaver head and could be unequivocally identified both on the CT image and in reality. The system accuracy was evaluated by determining the deviation of the real target position from the position indicated in the CT scan. The accuracy of the dental splint-based registration was compared to that of two standard registration procedures: contour-based laser surface registration and fixed marker registration.

Results: The mean accuracy of 0.55±0.28 mm obtained when using the maxillary splint device was similar to that obtained with the "gold standard" registration using bone-implanted markers (0.33±0.26 mm), while being clearly superior to that obtained with contour-based laser surface registration (1.91±0.74 mm).

Conclusions: Registration using the non-invasively fixed maxillary fiducial platform can provide sub-millimetric accuracy in the lateral skull base region. In vivo validation may prove dental splint-based registration to be an accurate and non-invasive alternative option for image guided surgery of the lateral skull base, and may facilitate the application of navigation systems in this delicate region.

目的:图像引导手术在额外侧颅底区域的广泛应用受到了限制,因为需要一种可靠的、无创的、提供亚毫米精度的配准程序。我们开发并验证了一种非侵入性、易于使用的注册设备,该设备基于牙夹板和横向安装的基准载体。方法:将6个钛靶基准螺钉固定在尸体头部外侧颅底区,对其进行重复精度测量,使其在CT图像和现实中都能明确识别。通过确定实际目标位置与CT扫描显示位置的偏差来评估系统精度。将基于牙夹板的配准精度与两种标准配准程序进行比较:基于轮廓的激光表面配准和固定标记物配准。结果:上颌夹板装置的平均精度为0.55±0.28 mm,与植骨标记物的“金标准”配准(0.33±0.26 mm)相似,明显优于基于轮廓的激光表面配准(1.91±0.74 mm)。结论:采用无创固定上颌基准平台对侧颅底区进行配准可达到亚毫米精度。体内验证可能证明基于牙夹板的配准是外侧颅底图像引导手术的一种准确且无创的替代选择,并可能促进导航系统在这一脆弱区域的应用。
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引用次数: 19
Cadaveric analysis of an accelerometer-based portable navigation device for distal femoral cutting block alignment in total knee arthroplasty. 全膝关节置换术中基于加速度计的便携式股骨远端切割块定位导航装置的尸体分析。
Q Medicine Pub Date : 2012-01-01 Epub Date: 2012-06-08 DOI: 10.3109/10929088.2012.689335
Denis Nam, Seth A Jerabek, Michael B Cross, David J Mayman

Femoral intramedullary guides have been shown to be insufficiently accurate in creating a distal femoral resection perpendicular to the mechanical axis in total knee arthroplasty (TKA), as they make assumptions regarding the difference between the patient's femoral mechanical and anatomical angles. The aim of this cadaveric study was to validate the accuracy of a portable accelerometer-based navigation device for alignment of the distal femoral cutting block in TKA. Twenty-nine trials were performed on five cadaveric specimens (hip-to-ankle), in which the distal femoral cutting block was placed using the KneeAlign 2™ navigation device. For each specimen, a preoperative "target" was assigned for varus/valgus and flexion/extension alignment of the cutting block. The actual alignment of each cutting block was then measured using the ORTHOsoft Computer Assisted Surgery (CAS) system. The mean absolute difference between the preoperative target and the alignment of the cutting block was 0.83 ± 0.60° for varus/valgus, and 0.83 ± 0.83° for flexion/extension. The KneeAlign 2™ navigation device can set and align the distal femoral resection guide with the same accuracy as a large-console CAS system, thus demonstrating that portable accelerometer-based navigation can be used reliably in total knee arthroplasty.

在全膝关节置换术(TKA)中,股骨髓内导具在创建垂直于机械轴的股骨远端切除时已被证明不够准确,因为它们假设了患者股骨机械角度和解剖角度之间的差异。本尸体研究的目的是验证便携式加速度计导航装置在TKA中股骨远端切割块对齐的准确性。在5个尸体标本(臀部到脚踝)上进行了29次试验,其中使用knneealign 2™导航装置放置股骨远端切割块。对于每个标本,术前“目标”被指定为内翻/外翻和屈伸对齐的切割块。然后使用ORTHOsoft计算机辅助手术(CAS)系统测量每个切割块的实际对齐。对于内翻/外翻,术前目标与切割块对齐的平均绝对差为0.83±0.60°,对于屈曲/伸展,平均绝对差为0.83±0.83°。knneealign 2™导航装置可以以与大型控制台CAS系统相同的精度设置和对准股骨远端切除导管,从而证明基于便携式加速度计的导航可以可靠地用于全膝关节置换术。
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引用次数: 14
期刊
Computer Aided Surgery
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