Setyoadi Setyoadi, F. Efendi, Joni Haryanto, Siti Fatmawati, N. Kristianingrum, Tina Handayani Nasution, Dina Dewi Sartika Lestari Ismail
Type 2 diabetes mellitus (T2DM) requires dietary compliance to manage elevated blood glucose levels. In calorie counseling, a client and counselor have conversations about calorie consumption problems related to type 2 diabetes. The study aimed to evaluate how calorie counseling affected T2DM patients’ adherence to their diets. A quasi-experimental design was employed to randomly assign 40 T2DM patients to the intervention (n=20) or control (n=20) groups. Food logs were gathered prior to and following counseling, and analysis was done using independent T-tests. The findings revealed a post-intervention mean discrepancy in calorie consumption of 132.08 Kcal. The results of the T-test analysis, however, showed that there was no significant difference between the groups (P=0.26>0.05), suggesting that group-based calorie counseling had no appreciable impact on diabetes diet compliance. Confounding variables like age, education, employment status, and family support could have impacted these results. It is advised that future studies consider how family support and demographic factors might improve diet compliance in T2DM patients. This method can lead to more effective interventions for this population and a more thorough understanding of the variables influencing dietary adherence.
{"title":"The effects of dietary compliance counseling on calorie consumption in type 2 diabetes mellitus","authors":"Setyoadi Setyoadi, F. Efendi, Joni Haryanto, Siti Fatmawati, N. Kristianingrum, Tina Handayani Nasution, Dina Dewi Sartika Lestari Ismail","doi":"10.4081/hls.2024.12095","DOIUrl":"https://doi.org/10.4081/hls.2024.12095","url":null,"abstract":"Type 2 diabetes mellitus (T2DM) requires dietary compliance to manage elevated blood glucose levels. In calorie counseling, a client and counselor have conversations about calorie consumption problems related to type 2 diabetes. The study aimed to evaluate how calorie counseling affected T2DM patients’ adherence to their diets. A quasi-experimental design was employed to randomly assign 40 T2DM patients to the intervention (n=20) or control (n=20) groups. Food logs were gathered prior to and following counseling, and analysis was done using independent T-tests. The findings revealed a post-intervention mean discrepancy in calorie consumption of 132.08 Kcal. The results of the T-test analysis, however, showed that there was no significant difference between the groups (P=0.26>0.05), suggesting that group-based calorie counseling had no appreciable impact on diabetes diet compliance. Confounding variables like age, education, employment status, and family support could have impacted these results. It is advised that future studies consider how family support and demographic factors might improve diet compliance in T2DM patients. This method can lead to more effective interventions for this population and a more thorough understanding of the variables influencing dietary adherence.","PeriodicalId":507714,"journal":{"name":"Healthcare in Low-resource Settings","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Empowering families can enhance their ability to detect high-risk pregnancies early, which can improve the health status of pregnant women. This study aimed to analyze the effect of the family empowerment model on the hemoglobin levels of pregnant women. It employed a quasi-experimental method with a cross-sectional study approach, implementing a family empowerment intervention to examine its impact on the health of pregnant women. Sampling was conducted using probability sampling with simple random sampling, resulting in 60 pregnant women divided equally into an intervention group and a control group. The independent variable was the family empowerment model intervention, and the dependent variable was the hemoglobin level of the pregnant women. Data were collected using a questionnaire and analyzed with the Wilcoxon test statistic, which indicated a significant effect (p=0.000) of the family empowerment model on the hemoglobin levels of pregnant women. The statistical analysis revealed that the intervention group’s hemoglobin levels showed a significant difference (p<0.05) before and after the intervention. In summary, the treatment involving the family empowerment model significantly affected the hemoglobin levels in pregnant women. After the intervention, nearly all respondents demonstrated increased family involvement in maintaining and caring for pregnant women, facilitating the early detection of high-risk pregnancies, and contributing to increased hemoglobin levels among these women.
{"title":"The effect of family empowerment on hemoglobin levels in pregnant women","authors":"Ika Mardiyanti, Aldilia Wyasti Pratama, Lailatul Khusnul Rizki, Esty Puji Rahayu","doi":"10.4081/hls.2024.11987","DOIUrl":"https://doi.org/10.4081/hls.2024.11987","url":null,"abstract":"Empowering families can enhance their ability to detect high-risk pregnancies early, which can improve the health status of pregnant women. This study aimed to analyze the effect of the family empowerment model on the hemoglobin levels of pregnant women. It employed a quasi-experimental method with a cross-sectional study approach, implementing a family empowerment intervention to examine its impact on the health of pregnant women. Sampling was conducted using probability sampling with simple random sampling, resulting in 60 pregnant women divided equally into an intervention group and a control group. The independent variable was the family empowerment model intervention, and the dependent variable was the hemoglobin level of the pregnant women. Data were collected using a questionnaire and analyzed with the Wilcoxon test statistic, which indicated a significant effect (p=0.000) of the family empowerment model on the hemoglobin levels of pregnant women. The statistical analysis revealed that the intervention group’s hemoglobin levels showed a significant difference (p<0.05) before and after the intervention. In summary, the treatment involving the family empowerment model significantly affected the hemoglobin levels in pregnant women. After the intervention, nearly all respondents demonstrated increased family involvement in maintaining and caring for pregnant women, facilitating the early detection of high-risk pregnancies, and contributing to increased hemoglobin levels among these women.","PeriodicalId":507714,"journal":{"name":"Healthcare in Low-resource Settings","volume":"62 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141683130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coronary Heart Disease (CHD) is the leading cause of death worldwide and is rising, annually. Improved health outcomes require early treatment and self-monitoring, which need health literacy. This study examined how health literacy affects CHD patients’ Quality of Life (QoL) at the Hospital’s Cardiology Clinic. This quantitative, descriptive correlation study was cross-sectional. The sample was 164 respondents, sampled consecutively. Patients must be willing to participate, diagnosed with CHD, and attend cardiology outpatient follow-up appointments. Health literacy was measured with the HLS-EU-SQ10 and QoL with the Seattle Angina Questionnaire. This study used chi-square to analyze the relationship between two ordinal scale variables in a contingency table. The average age was 58.07 years, according to research. Of the respondents, 59 (36.0%) had graduated high school. Health literacy was assessed in three QoL domains: physical limitation (P=0.024), angina frequency (P=0.570), and QoL (P=0.338). Service agencies should be able to use pamphlets to improve health literacy and provide rehabilitation to acute coronary syndrome patients to improve QoL.
{"title":"Examining the relationship between health literacy and quality of life in patients with coronary heart disease: a quantitative study at a cardiology clinic","authors":"Lita Lita, Nadila Khairiyah, Agnita Utami, Silvia Nora Anggreini, Faridah Mohd. Said","doi":"10.4081/hls.2024.11851","DOIUrl":"https://doi.org/10.4081/hls.2024.11851","url":null,"abstract":"Coronary Heart Disease (CHD) is the leading cause of death worldwide and is rising, annually. Improved health outcomes require early treatment and self-monitoring, which need health literacy. This study examined how health literacy affects CHD patients’ Quality of Life (QoL) at the Hospital’s Cardiology Clinic. This quantitative, descriptive correlation study was cross-sectional. The sample was 164 respondents, sampled consecutively. Patients must be willing to participate, diagnosed with CHD, and attend cardiology outpatient follow-up appointments. Health literacy was measured with the HLS-EU-SQ10 and QoL with the Seattle Angina Questionnaire. This study used chi-square to analyze the relationship between two ordinal scale variables in a contingency table. The average age was 58.07 years, according to research. Of the respondents, 59 (36.0%) had graduated high school. Health literacy was assessed in three QoL domains: physical limitation (P=0.024), angina frequency (P=0.570), and QoL (P=0.338). Service agencies should be able to use pamphlets to improve health literacy and provide rehabilitation to acute coronary syndrome patients to improve QoL.","PeriodicalId":507714,"journal":{"name":"Healthcare in Low-resource Settings","volume":"4 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141681600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ernani Setyawati, Endah Wijayanti, Ita Kusumayanti, Damai Noviasari, Sekar Handayani, Novi Pasiriani, Eli Rahmawati
The sustainability of breastfeeding remains a challenge for primiparous mothers. Empowering women through home visits by midwives needs to be enhanced to ensure the continuity of breastfeeding. This research aimed to compare the effectiveness of the SETIA (Self-Empowering Women, Empathy, Trust, Intimacy, and Affection) program with a standard program in assisting primiparous mothers to breastfeed their babies after one month. A total of 50 primiparous participants were divided into two groups through simple random sampling. The standard group received four home visits, while the SETIA group received five home visits within one month postpartum. The breastfeeding competency variable was evaluated after one month using the World Health Organization (WHO) instruments and interviews about exclusive breastfeeding. The variables were analyzed using comparative statistics. The results showed no significant difference between the standard and SETIA groups, with Mann-Whitney U values of 253.5 and Wilcoxon values of 578.5 (p-value=0.086, α<0.05). However, there is evidence that the intervention group managed breastfeeding problems better, and more mothers continued breastfeeding after one month. Therefore, the authors suggest more frequent home visits to help new mothers adapt to their breastfeeding roles, especially in the first week after birth. Further research is needed to assess exclusive breastfeeding after six months in both groups.
{"title":"Effectiveness of the SETIA (Self Empowering Woman, Empathy, Trust, Intimate and Affection) program in enhancing exclusive breastfeeding in Indonesia","authors":"Ernani Setyawati, Endah Wijayanti, Ita Kusumayanti, Damai Noviasari, Sekar Handayani, Novi Pasiriani, Eli Rahmawati","doi":"10.4081/hls.2024.12089","DOIUrl":"https://doi.org/10.4081/hls.2024.12089","url":null,"abstract":"The sustainability of breastfeeding remains a challenge for primiparous mothers. Empowering women through home visits by midwives needs to be enhanced to ensure the continuity of breastfeeding. This research aimed to compare the effectiveness of the SETIA (Self-Empowering Women, Empathy, Trust, Intimacy, and Affection) program with a standard program in assisting primiparous mothers to breastfeed their babies after one month. A total of 50 primiparous participants were divided into two groups through simple random sampling. The standard group received four home visits, while the SETIA group received five home visits within one month postpartum. The breastfeeding competency variable was evaluated after one month using the World Health Organization (WHO) instruments and interviews about exclusive breastfeeding. The variables were analyzed using comparative statistics. The results showed no significant difference between the standard and SETIA groups, with Mann-Whitney U values of 253.5 and Wilcoxon values of 578.5 (p-value=0.086, α<0.05). However, there is evidence that the intervention group managed breastfeeding problems better, and more mothers continued breastfeeding after one month. Therefore, the authors suggest more frequent home visits to help new mothers adapt to their breastfeeding roles, especially in the first week after birth. Further research is needed to assess exclusive breastfeeding after six months in both groups.","PeriodicalId":507714,"journal":{"name":"Healthcare in Low-resource Settings","volume":" 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dedes Fitria, Sri Wahyuni, Elin Supliyani, Fauzia Djamilus, Ari Kurniarum, Sri Sumarni
Adolescents with disabilities deserve the best health care without discrimination. They can access gender-sensitive health care and rehabilitation. Health services include promotive, preventive, curative, and rehabilitative care. HIV and AIDS prevention in disabled people must start as soon as possible. Those with speech disabilities are encouraged to reach their full independence potential in case of an incident. This study tested an HIV/AIDS education model for speech-impaired people. At Indonesia's School of Disability, a non-randomized control group pre- and post-test design was used. In the study, 60 speech-impaired students were divided into 30 intervention and 30 control groups. Analyses used T-tests. Speech-disabled people's knowledge and attitudes improved with the virtual HIV/AIDS education model (P=0.007). Therefore, the HIV/AIDS education model should be implemented using virtual platforms to improve knowledge and attitudes, especially among speech-disabled teens. Virtual reproductive health education for children with speech disabilities improves knowledge and attitudes more than traditional methods, especially among visually impaired children.
残疾青少年应不受歧视地获得最好的医疗保健。他们可以获得对性别问题有敏感认识的保健和康复服务。保健服务包括促进、预防、治疗和康复护理。必须尽早开始预防残疾人感染艾滋病毒和艾滋病。鼓励有语言障碍的人充分发挥其独立潜能，以防不测。本研究测试了针对语言障碍者的艾滋病教育模式。印度尼西亚残疾学校采用了非随机对照组前后测试设计。研究中，60 名语言障碍学生被分为 30 个干预组和 30 个对照组。分析采用 T 检验。在虚拟艾滋病教育模式下，语言残疾人的知识和态度都有所改善（P=0.007）。因此，应利用虚拟平台实施艾滋病教育模式，以改善知识和态度，尤其是语言障碍青少年的知识和态度。针对语言残疾儿童的虚拟生殖健康教育比传统方法更能改善知识和态度，尤其是在视障儿童中。
{"title":"The effectiveness of HIV/AIDS education models for adolescents with speech disabilities","authors":"Dedes Fitria, Sri Wahyuni, Elin Supliyani, Fauzia Djamilus, Ari Kurniarum, Sri Sumarni","doi":"10.4081/hls.2024.11973","DOIUrl":"https://doi.org/10.4081/hls.2024.11973","url":null,"abstract":"Adolescents with disabilities deserve the best health care without discrimination. They can access gender-sensitive health care and rehabilitation. Health services include promotive, preventive, curative, and rehabilitative care. HIV and AIDS prevention in disabled people must start as soon as possible. Those with speech disabilities are encouraged to reach their full independence potential in case of an incident. This study tested an HIV/AIDS education model for speech-impaired people. At Indonesia's School of Disability, a non-randomized control group pre- and post-test design was used. In the study, 60 speech-impaired students were divided into 30 intervention and 30 control groups. Analyses used T-tests. Speech-disabled people's knowledge and attitudes improved with the virtual HIV/AIDS education model (P=0.007). Therefore, the HIV/AIDS education model should be implemented using virtual platforms to improve knowledge and attitudes, especially among speech-disabled teens. Virtual reproductive health education for children with speech disabilities improves knowledge and attitudes more than traditional methods, especially among visually impaired children.","PeriodicalId":507714,"journal":{"name":"Healthcare in Low-resource Settings","volume":"63 s239","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hypertension remains a significant global public health concern. Non-pharmacological interventions such as light massage and the Spiritual Emotional Freedom Technique (SEFT) offer potential avenues to mitigate sustained increases in blood pressure among patients with hypertension. However, research exploring these methods as alternative therapies, particularly in Indonesia, is limited. This study aimed to investigate the effects of light massage and SEFT on the blood pressure of hypertensive individuals. Employing a quasi-experimental design with a time series approach, the study utilized purposive sampling to select 27 participants. Light massage and SEFT were considered independent variables, while blood pressure served as the dependent variable. Data analysis involved repeated measures ANOVA and one-way ANOVA tests. The results revealed significant differences in mean blood pressure before and after the light massage intervention (p-values: 0.002, <0.001, <0.001). The intervention sessions yielded the most significant results (p-values: <0.001, 0.002, <0.001), whereas no differences were observed in the control group (systolic and Mean Arterial Pressure, MAP, p-values: 0.012 and 0.017, respectively). Notably, there were discrepancies in mean blood pressure before and after interventions in both the light massage and SEFT groups, indicating a potential benefit of these interventions. Conversely, no such differences were noted in the control group. These results highlight the potential benefits of integrating light massage and SEFT into holistic approaches for managing hypertension, potentially improving outcomes and quality of life for affected individuals.
{"title":"The effect of light massage and Spiritual Emotional Freedom Technique interventions on blood pressure among hypertension patients in Indonesia","authors":"Arsyawina Arsyawina, Rivan Firdaus, Diah Setiani, Raisyah Chaiarunnisya","doi":"10.4081/hls.2024.11958","DOIUrl":"https://doi.org/10.4081/hls.2024.11958","url":null,"abstract":"Hypertension remains a significant global public health concern. Non-pharmacological interventions such as light massage and the Spiritual Emotional Freedom Technique (SEFT) offer potential avenues to mitigate sustained increases in blood pressure among patients with hypertension. However, research exploring these methods as alternative therapies, particularly in Indonesia, is limited. This study aimed to investigate the effects of light massage and SEFT on the blood pressure of hypertensive individuals. Employing a quasi-experimental design with a time series approach, the study utilized purposive sampling to select 27 participants. Light massage and SEFT were considered independent variables, while blood pressure served as the dependent variable. Data analysis involved repeated measures ANOVA and one-way ANOVA tests. The results revealed significant differences in mean blood pressure before and after the light massage intervention (p-values: 0.002, <0.001, <0.001). The intervention sessions yielded the most significant results (p-values: <0.001, 0.002, <0.001), whereas no differences were observed in the control group (systolic and Mean Arterial Pressure, MAP, p-values: 0.012 and 0.017, respectively). Notably, there were discrepancies in mean blood pressure before and after interventions in both the light massage and SEFT groups, indicating a potential benefit of these interventions. Conversely, no such differences were noted in the control group. These results highlight the potential benefits of integrating light massage and SEFT into holistic approaches for managing hypertension, potentially improving outcomes and quality of life for affected individuals.","PeriodicalId":507714,"journal":{"name":"Healthcare in Low-resource Settings","volume":"303 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141692129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Le-Diabet is an Android mobile application developed for diabetes management whose effectiveness has remained unknown. This research aimed to investigate its impact on self-efficacy and blood glucose levels in patients with diabetes. Employing a quasi-experimental approach, the study utilized a pretest and posttest control group design. The sample included 28 respondents in the control group and 34 in the intervention group, selected through purposive sampling based on criteria such as diagnosed diabetes, smartphone usage, and 6 weeks of using the Le-Diabet application. Self-efficacy was measured using the Diabetes Management Self-Efficacy Scale, while blood glucose levels were monitored with a glucometer. Data analysis involved paired and unpaired t-tests. The results revealed a significant increase in self-efficacy scores by 3.1 points [p=0.000, 95% confidence interval (CI) = -6.006 to -1.876] in the intervention group, whereas the control group experienced a decrease of 1.9 points. Both groups exhibited an increase in blood glucose levels, with a significant rise of 35.6 mg/dL (p=0.035, 95% CI = -68.578 to -2.636) in the control group and a non-significant increase of 3.59 mg/dL (p=0.076, 95% CI = -22.759 to 15.582) in the intervention group. The research concludes that the use of the Le-Diabet application enhances self-efficacy and maintains blood glucose level stability; however, it has not shown an impact on metabolic syndrome indicators in diabetic patients. Further research is needed, utilizing a larger and more diverse sample from various age groups and extending the duration of the study to evaluate the long-term impact of the applied intervention.
{"title":"The impact of the Le-Diabet application on self-efficacy and blood glucose levels in diabetes mellitus patients","authors":"Lina Erlina, Widi Hastuti","doi":"10.4081/hls.2024.11984","DOIUrl":"https://doi.org/10.4081/hls.2024.11984","url":null,"abstract":"Le-Diabet is an Android mobile application developed for diabetes management whose effectiveness has remained unknown. This research aimed to investigate its impact on self-efficacy and blood glucose levels in patients with diabetes. Employing a quasi-experimental approach, the study utilized a pretest and posttest control group design. The sample included 28 respondents in the control group and 34 in the intervention group, selected through purposive sampling based on criteria such as diagnosed diabetes, smartphone usage, and 6 weeks of using the Le-Diabet application. Self-efficacy was measured using the Diabetes Management Self-Efficacy Scale, while blood glucose levels were monitored with a glucometer. Data analysis involved paired and unpaired t-tests. The results revealed a significant increase in self-efficacy scores by 3.1 points [p=0.000, 95% confidence interval (CI) = -6.006 to -1.876] in the intervention group, whereas the control group experienced a decrease of 1.9 points. Both groups exhibited an increase in blood glucose levels, with a significant rise of 35.6 mg/dL (p=0.035, 95% CI = -68.578 to -2.636) in the control group and a non-significant increase of 3.59 mg/dL (p=0.076, 95% CI = -22.759 to 15.582) in the intervention group. The research concludes that the use of the Le-Diabet application enhances self-efficacy and maintains blood glucose level stability; however, it has not shown an impact on metabolic syndrome indicators in diabetic patients. Further research is needed, utilizing a larger and more diverse sample from various age groups and extending the duration of the study to evaluate the long-term impact of the applied intervention.","PeriodicalId":507714,"journal":{"name":"Healthcare in Low-resource Settings","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141716680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In social life and global health, infertility is common. History of abdominal surgery, body mass index (BMI), endometriosis, menstrual history, and polycystic ovarian syndrome (PCOS) have not been fully explained as female infertility factors. This study examined infertility causes at ASHA in vitro fertilization Primasatya Husada Citra (PHC) Hospital Surabaya. This quantitative study was cross-sectional. In May-July 2023, 82 childbearing-age women with infertility issues visited the hospital and completed questionnaires. Description and analysis were performed using the Wilcoxon rank test to evaluate menstrual history, BMI, PCOS, endometriosis, and abdominal surgery history in relation to infertility. Infertility was statistically associated with abdominal surgery history (P=0.008), BMI (P=0.000), endometriosis diagnosis (P=0.000), and PCOS (P=0.000). Women with abdominal surgery, endometriosis, and PCOS had significant infertility. Women’s infertility can be caused by ovulation disorders, tubal and pelvic disorders, or uterine disorders, but one-third of cases are unexplained. Infertility treatment may benefit from addressing abdominal surgery history, BMI, endometriosis, and PCOS. Early intervention and targeted care based on these determinants may improve fertility outcomes and reduce unexplained infertility.
{"title":"Analysis of determinants of infertility among women at in vitro fertilization clinic in Surabaya","authors":"Yati Isnaini Safitri, Esty Puji Rahayu, Lailatul Khusnul Rizki, Siska Nurul Abidah, Ima Nadatien","doi":"10.4081/hls.2024.11985","DOIUrl":"https://doi.org/10.4081/hls.2024.11985","url":null,"abstract":"In social life and global health, infertility is common. History of abdominal surgery, body mass index (BMI), endometriosis, menstrual history, and polycystic ovarian syndrome (PCOS) have not been fully explained as female infertility factors. This study examined infertility causes at ASHA in vitro fertilization Primasatya Husada Citra (PHC) Hospital Surabaya. This quantitative study was cross-sectional. In May-July 2023, 82 childbearing-age women with infertility issues visited the hospital and completed questionnaires. Description and analysis were performed using the Wilcoxon rank test to evaluate menstrual history, BMI, PCOS, endometriosis, and abdominal surgery history in relation to infertility. Infertility was statistically associated with abdominal surgery history (P=0.008), BMI (P=0.000), endometriosis diagnosis (P=0.000), and PCOS (P=0.000). Women with abdominal surgery, endometriosis, and PCOS had significant infertility. Women’s infertility can be caused by ovulation disorders, tubal and pelvic disorders, or uterine disorders, but one-third of cases are unexplained. Infertility treatment may benefit from addressing abdominal surgery history, BMI, endometriosis, and PCOS. Early intervention and targeted care based on these determinants may improve fertility outcomes and reduce unexplained infertility.","PeriodicalId":507714,"journal":{"name":"Healthcare in Low-resource Settings","volume":"221 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141692482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Zainul, V. D. Kharisma, Pauline Ciuputri, A. Ansori, Mochammad Aqilah Herdiansyah, Sukma Sahadewa, F. D. Durry
HIV-2 infection is a unique concern with fewer cases than HIV-1, but it poses a high mortality rate due to its resistance to all HIV-1 antiretroviral treatments. This study focuses on one type of antiretroviral, reverse transcriptase (RT) inhibitors, as they play an important role in HIV-2 replication. The screening of potential HIV-2 antiretroviral candidates was carried out using compounds from elderberry (Sambucus nigra L.) flower extract. There is a lack of research on the antiviral potential of elderberry flower extracts, particularly in HIV-2; therefore, this study is important to explain the molecular mechanism underlying the potential of elderberry (Sambucus nigra L.) flower extracts to inhibit RT activity in HIV-2 through bioinformatics simulations. This study uses the in silico method, involving sample preparation in the database, drug-like molecular prediction through the server, molecular docking simulation, chemical bond interaction analysis, and three-dimensional structure visualization. Isorhamnetin has the most negative binding affinity of -9.9 kcal/mol compared to other compounds. It interacts with the HIV-2 RT domain at residues Trp4(B), Pro25(B), Asn137(B), Pro133(B), Gln23(B), Pro140(B), Leu21(B), Ile90(A), Thr131(B), Asn57(B), Arg22(B), and Glu89(A) with hydrophobic bond interactions. Hydrogen bond interactions are formed at the positions of Ser134(B), Gly141(B), and Thr88(A). Isorhamnetin from elderberry (Sambucus nigra L.) flower extract could be a potential HIV-2 antiretroviral candidate because it has the most negative binding affinity and the formation of hydrophobic hydrogen bond interactions on the RT domain.
{"title":"Antiretroviral activity from elderberry (Sambucus nigra L.) flowers against HIV-2 infection via reverse transcriptase inhibition: a viroinformatics study","authors":"R. Zainul, V. D. Kharisma, Pauline Ciuputri, A. Ansori, Mochammad Aqilah Herdiansyah, Sukma Sahadewa, F. D. Durry","doi":"10.4081/hls.2024.12047","DOIUrl":"https://doi.org/10.4081/hls.2024.12047","url":null,"abstract":"\u0000HIV-2 infection is a unique concern with fewer cases than HIV-1, but it poses a high mortality rate due to its resistance to all HIV-1 antiretroviral treatments. This study focuses on one type of antiretroviral, reverse transcriptase (RT) inhibitors, as they play an important role in HIV-2 replication. The screening of potential HIV-2 antiretroviral candidates was carried out using compounds from elderberry (Sambucus nigra L.) flower extract. There is a lack of research on the antiviral potential of elderberry flower extracts, particularly in HIV-2; therefore, this study is important to explain the molecular mechanism underlying the potential of elderberry (Sambucus nigra L.) flower extracts to inhibit RT activity in HIV-2 through bioinformatics simulations. This study uses the in silico method, involving sample preparation in the database, drug-like molecular prediction through the server, molecular docking simulation, chemical bond interaction analysis, and three-dimensional structure visualization. Isorhamnetin has the most negative binding affinity of -9.9 kcal/mol compared to other compounds. It interacts with the HIV-2 RT domain at residues Trp4(B), Pro25(B), Asn137(B), Pro133(B), Gln23(B), Pro140(B), Leu21(B), Ile90(A), Thr131(B), Asn57(B), Arg22(B), and Glu89(A) with hydrophobic bond interactions. Hydrogen bond interactions are formed at the positions of Ser134(B), Gly141(B), and Thr88(A). Isorhamnetin from elderberry (Sambucus nigra L.) flower extract could be a potential HIV-2 antiretroviral candidate because it has the most negative binding affinity and the formation of hydrophobic hydrogen bond interactions on the RT domain.\u0000","PeriodicalId":507714,"journal":{"name":"Healthcare in Low-resource Settings","volume":"48 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141345171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Infertility poses multifaceted challenges, prompting many women to explore complementary and alternative medicine (CAM). This study investigated CAM prevalence and types among infertile women in Khartoum. A descriptive cross-sectional study was conducted, involving 253 women. Data was collected through structured interviews, and descriptive and inferential statistics, with a significance level set at p>0.05. The mean age of the participants was 31.59±6.9 years, with 53.8% being graduates, 54.5% diagnosed with primary infertility, and 45.5% with secondary infertility. CAM usage was reported by 52.2% of participants, with herbal treatments being the most prevalent (e.g., fenugreek 26.9%, argell 20.2%). Spiritual healing (11.4%) and folkloric methods (9.5%) were also noted. Most users (76.5%) did not disclose CAM usage to healthcare providers, citing beliefs in safety (56.8%) and effectiveness (39.4%). Family (72%) and friends (46%) significantly influenced CAM use. Infertility duration and rural residence were associated with CAM usage (p=0.002). The study underscores a high prevalence of CAM usage among Sudanese infertile women, primarily herbal remedies, and emphasizes the importance of healthcare providers engaging patients in CAM utilization.
{"title":"Prevalence and correlates of complementary and alternative medicine utilization among infertile women attending selected fertility clinics in Khartoum state","authors":"M. Elmahdy, Faiza Ali Nasor","doi":"10.4081/hls.2024.12319","DOIUrl":"https://doi.org/10.4081/hls.2024.12319","url":null,"abstract":"\u0000Infertility poses multifaceted challenges, prompting many women to explore complementary and alternative medicine (CAM). This study investigated CAM prevalence and types among infertile women in Khartoum. A descriptive cross-sectional study was conducted, involving 253 women. Data was collected through structured interviews, and descriptive and inferential statistics, with a significance level set at p>0.05. The mean age of the participants was 31.59±6.9 years, with 53.8% being graduates, 54.5% diagnosed with primary infertility, and 45.5% with secondary infertility. CAM usage was reported by 52.2% of participants, with herbal treatments being the most prevalent (e.g., fenugreek 26.9%, argell 20.2%). Spiritual healing (11.4%) and folkloric methods (9.5%) were also noted. Most users (76.5%) did not disclose CAM usage to healthcare providers, citing beliefs in safety (56.8%) and effectiveness (39.4%). Family (72%) and friends (46%) significantly influenced CAM use. Infertility duration and rural residence were associated with CAM usage (p=0.002). The study underscores a high prevalence of CAM usage among Sudanese infertile women, primarily herbal remedies, and emphasizes the importance of healthcare providers engaging patients in CAM utilization.\u0000","PeriodicalId":507714,"journal":{"name":"Healthcare in Low-resource Settings","volume":"10 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141353725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：