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Writing Case Reports Can Improve Seven Components in Clinical Reasoning 撰写病例报告可提高临床推理能力的七个组成部分
Pub Date : 2024-03-01 DOI: 10.2147/imcrj.s449310
Toshinori Nishizawa, Kosuke Ishizuka, Yuki Otsuka, Toshiyuki Nakanishi, Akira Kawashima, Taiju Miyagami, S. Yamashita
: Case reports provide scientific knowledge and opportunities for new clinical research. However, it is estimated that less than 5% of cases presented by Japanese generalists at academic conferences are published due to various barriers such as the complex process of writing articles, conducting literature searches, the significant time required, the reluctance to write in English, and the challenge of selecting appropriate journals for publication. Therefore, the purpose of this opinion paper is to provide clinicians with practical tips for writing case reports that promote diagnostic excellence. In recent years, clinical practitioners have been striving for diagnostic excellence and optimal methods to accurately and comprehensively understand the patient’s condition. To write a case report, it is essential to be mindful of the elements of diagnostic excellence and consider the quality of the diagnostic reasoning process. We (the authors) are seven academic generalists who are members of the Japanese Society of Hospital General Medicine (JSHGM) – Junior Doctors Association, with a median of 7 years after graduation and extensive experience publishing case reports in international peer-reviewed journals. We conducted a narrative review and discussed ways to write case reports to promote diagnostic excellence, leveraging our unique perspectives as academic generalists. Our review did not identify any reports addressing the critical points in writing case reports that embody diagnostic excellence. Therefore, this report proposes a methodology that describes the process involved in writing diagnostic excellence-promoting case reports and provides an overview of the lessons learned. Based on our review and discussion, we explain the essential points for promoting diagnostic excellence through case reports categorized into seven components of clinical reasoning. These strategies are useful in daily clinical practice and instrumental in promoting diagnostic excellence through case reports.
:病例报告为新的临床研究提供了科学知识和机会。然而,据估计,日本普通医生在学术会议上发表的病例报告只有不到 5%得以发表,原因是存在各种障碍,如撰写文章、进行文献检索的复杂过程、所需的大量时间、不愿用英语撰写以及选择合适期刊发表的挑战。因此,本意见书旨在为临床医生提供撰写病例报告的实用技巧,以促进卓越诊断。近年来,临床医生一直在努力追求卓越的诊断效果和最佳的诊断方法,以准确、全面地了解患者的病情。撰写病例报告时,必须注意卓越诊断的要素,并考虑诊断推理过程的质量。我们(作者)是日本医院全科医学会(JSHGM)--初级医生协会的七名学术型全科医生,毕业后的工作年限中位数为 7 年,在国际同行评审期刊上发表病例报告的经验丰富。我们进行了叙述性回顾,并讨论了如何撰写病例报告以促进卓越诊断,充分利用我们作为学术全科医生的独特视角。我们的综述没有发现任何报告论述了撰写体现卓越诊断的病例报告的关键点。因此,本报告提出了一种方法,描述了撰写促进卓越诊断的病例报告的过程,并概述了所吸取的经验教训。在回顾和讨论的基础上,我们将通过病例报告促进卓越诊断的要点归纳为临床推理的七个组成部分。这些策略在日常临床实践中非常有用,有助于通过病例报告促进卓越诊断。
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引用次数: 0
Lower Motor Neuron Facial Palsy Following COVID-19 Infection and COVID-19 AZD1222 Vaxzervria (AstraZeneca) Vaccine Administration: Two Case Reports 接种 COVID-19 AZD1222 Vaxzervria(阿斯利康)疫苗后出现下运动神经元面瘫:两个病例报告
Pub Date : 2024-03-01 DOI: 10.2147/imcrj.s453158
Khabab Abbasher Hussien Mohamed Ahmed, A. Siddig, AlHussien Abbashar, Mohammed Abbasher, Abubaker Alsedig Abbasher, A. Hussien, Gaffar Alemam A Manhal
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引用次数: 0
Whole-Exome Sequencing Identifies DYNC2H1 Mutations as a Cause of Jeune Asphyxiating Thoracic Dystrophy Without Extra‐Skeletal Organ Involvement 全基因组测序发现DYNC2H1突变是无骨骼外器官受累的幼年窒息性胸廓营养不良症的病因之一
Pub Date : 2024-03-01 DOI: 10.2147/imcrj.s447466
A. Asseri, Ahmad Alzoani, Mohammed Almahdi, Hussein Almahdi, Nouf Almushayt, Noha Alyazidi, Basmah M Al Mufarrih
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引用次数: 0
Pneumonia Caused by Chlamydia psittaci and SARS-CoV-2 Coinfection Diagnosed Using Metagenomic Next-Generation Sequencing: A Case Report 利用元基因组下一代测序诊断鹦鹉热衣原体引起的肺炎和 SARS-CoV-2 合并感染:病例报告
Pub Date : 2024-03-01 DOI: 10.2147/imcrj.s458131
Anbing Zhang, Jinguang Liang, Xiaoli Lao, Xiuqiong Xia, Jianping Liang
: We report a case of pneumonia caused by coinfection with Chlamydia psittaci and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron XBB.1 variant, confirmed using metagenomic next-generation sequencing (mNGS) and quantitative polymerase chain reaction (qPCR). C. psittaci and SARS-CoV-2 were detected in bronchoalveolar lavage fluid using mNGS. Additionally, mNGS detected C. psittaci in blood and nasopharyngeal specimens and was more sensitive than qPCR. The patient recovered after treatment with moxifloxacin. This report highlights the use of coinfections of C. psittaci and SARS-CoV-2, as mNGS has already been recognized to be a diagnostic tool for identifying coinfections.
:我们报告了一例由鹦鹉热衣原体和严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)Omicron XBB.1 变体合并感染引起的肺炎病例,该病例通过元基因组新一代测序(mNGS)和定量聚合酶链反应(qPCR)得到了证实。利用 mNGS 在支气管肺泡灌洗液中检测到了鹦鹉热杆菌和 SARS-CoV-2 。此外,mNGS 还能检测到血液和鼻咽标本中的鹦鹉热杆菌,其灵敏度高于 qPCR。患者在接受莫西沙星治疗后康复。本报告强调了鹦鹉热杆菌和 SARS-CoV-2 协同感染的应用,因为 mNGS 已被认为是识别协同感染的诊断工具。
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引用次数: 0
Evaluation of Oral Health-Related Quality of Life in Patient with Herpes-Associated Erythema Multiforme: A Unique Case Report 评估多形性疱疹患者与口腔健康相关的生活质量:一份独特的病例报告
Pub Date : 2024-03-01 DOI: 10.2147/IMCRJ.S456301
Fitrah Bakti, T. Dewi
Introduction Erythema multiforme (EM) is an acute mucocutaneous hypersensitivity reaction with various etiological factors, including herpes simplex virus type 1 (HSV-1) infection, known as herpes-associated erythema multiforme (HAEM). Oral health-related quality of life (OHRQoL) is a multidimensional concept of biopsychosocial aspects related to oral health. OHRQol contains information for patient-centered treatment plan development. The OHRQoL measurement instrument widely used by clinicians is the oral health impact profile-14 (OHIP-14). This case report aimed to evaluate OHRQoL in HAEM patient, which only manifests on the lips and oral cavity. Case A 25-year-old male patient came to the Department of Oral Medicine with the chief complaint of painful canker sores on the lips. Extra-oral examination revealed serosanguineous crusts on the lips that were painful and easily bleed. Intra-oral examination showed diffused and painful irregular erythematous lesions on the upper and lower labial mucosa. The anti-HSV1 IgG test was positive. The patient was diagnosed with HAEM. Case Management Pharmacological therapy included triamcinolone acetonide 0.1% in orabase, acyclovir tablets, multivitamins, and 0.9% NaCl. Non-pharmacological therapy included advice on maintaining good oral hygiene, avoiding spicy and sour foods, and breaking the bad habit of licking the lips. Conclusion The patient’s physical, psychological, and social conditions showed improvement and returned to normal after 7 days of treatment. In conclusion, oral health is an important factor that can improve the quality of life of HAEM patient.
导言:多形性红斑(EM)是一种急性粘膜超敏反应,有多种致病因素,包括单纯疱疹病毒 1 型(HSV-1)感染,被称为疱疹相关性多形性红斑(HAEM)。口腔健康相关生活质量(OHRQoL)是与口腔健康相关的生物-心理-社会多维概念。OHRQol 包含以患者为中心制定治疗计划的信息。临床医生广泛使用的 OHRQoL 测量工具是口腔健康影响档案-14(OHIP-14)。本病例报告旨在评估仅表现在嘴唇和口腔的 HAEM 患者的 OHRQoL。病例 一位 25 岁的男性患者来到口腔内科就诊,主诉是嘴唇上出现疼痛的口腔溃疡。口腔外检查发现嘴唇上有血清样痂皮,疼痛且易出血。口腔内部检查显示,上下唇粘膜有弥漫性不规则红斑,疼痛难忍。抗HSV1 IgG检测呈阳性。患者被诊断为 HAEM。病例管理 药物治疗包括 0.1% 奥拉帕斯曲安奈德、阿昔洛韦片剂、多种维生素和 0.9% 氯化钠。非药物治疗包括建议患者保持良好的口腔卫生、避免酸辣食物和改掉舔嘴唇的坏习惯。结论 经过 7 天的治疗,患者的身体、心理和社交状况均有所改善,恢复正常。总之,口腔健康是改善 HAEM 患者生活质量的重要因素。
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引用次数: 0
A Case Report of Herpes Zoster After Botulinum Toxin Injections 肉毒杆菌毒素注射后的带状疱疹病例报告
Pub Date : 2024-03-01 DOI: 10.2147/imcrj.s457239
Shadi Zari
Abstract This case report presents a rare occurrence of herpes zoster (HZ) outbreak in a 50-year-old male following botulinum toxin (BTX) type A injections. The patient developed burning swollen lesions on the left forehead four days after receiving BTX injections. Physical examination revealed papules and erosions in a dermatomal distribution. He was diagnosed with HZ and promptly treated with oral acyclovir. The lesions resolved within two weeks without complications. Previous literature reports a few similar HZ outbreaks following aesthetic treatments with BTX injections. The exact mechanism triggering varicella reactivation in these cases remains unclear. Prompt diagnosis and treatment of HZ are crucial in order to minimize outbreak duration and reduce complications. Physicians should maintain awareness of HZ as a potential complication following BTX injections.
摘要 本病例报告了一名 50 岁男性在注射 A 型肉毒毒素(BTX)后发生带状疱疹(HZ)爆发的罕见病例。患者在注射 BTX 四天后,左前额出现灼热肿胀的皮损。体格检查发现丘疹和糜烂呈皮节分布。他被诊断为 HZ,并迅速接受了口服阿昔洛韦治疗。皮损在两周内消退,未出现并发症。以往的文献报道了一些类似的 HZ 在注射 BTX 美容治疗后爆发的情况。在这些病例中,引发水痘再激活的确切机制仍不清楚。及时诊断和治疗 HZ 对缩短疫情持续时间和减少并发症至关重要。医生应始终将 HZ 作为 BTX 注射后的一种潜在并发症。
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引用次数: 0
Diagnosis of Thyroid Neoplasm-Associated Dermatomyositis in Ethiopian Woman 埃塞俄比亚妇女甲状腺肿瘤相关皮肌炎的诊断
Pub Date : 2024-03-01 DOI: 10.2147/imcrj.s448187
Gebrehiwot Legese, Y. Tesfaye, Eleni Ayele, Desalew Ayalew, Aron Abebaw, T. Gurji, A. Tadesse
Background: Dermatomyositis is an inflammatory myopathies causing proximal muscle weakness accompanied by muscular inflammation and skin rash. Dermatomyositis patients have a higher incidence of malignancy as compared to the general population. Case Report: A 52-year-old known female patient with a toxic multi-nodular goiter presented with insidious onset of itchy erythematous rash on her neck and bilateral hands and progressive muscle weakness of 4 months’ duration. Associated with this, she had photosensitivity, and periorbital edema of 2 months’ duration. On physical examination, she had an anterior neck mass, proximal muscle weakness, periorbital edema, and violaceous skin rash on her bilateral arms, shoulders and neck. Thyroid function tests were normal, creatinine kinase was elevated, and muscle biopsy revealed inflammatory myositis. Ultrasound of the anterior neck mass and analysis of fine needle aspiration suggested thyroid cancer. Conclusion: A high index of clinical suspicion is usually required for early diagnosis of dermatomyositis in resource-limited settings in order to prevent adverse outcomes and identify associated malignancies.
背景:皮肌炎是一种炎症性肌病,会导致近端肌肉无力,并伴有肌肉炎症和皮疹。与普通人群相比,皮肌炎患者的恶性肿瘤发病率较高。病例报告:一名 52 岁的女性患者,患有毒性多结节性甲状腺肿,隐匿性发病,颈部和双侧手部出现瘙痒性红斑皮疹,并持续 4 个月出现进行性肌无力。与此同时,她还出现了光敏感和持续两个月的眶周水肿。体格检查时,她的颈部前部有肿块,近端肌肉无力,眶周水肿,双臂、肩膀和颈部有荨麻疹。甲状腺功能检查正常,肌酸激酶升高,肌肉活检显示患有炎性肌炎。颈部前部肿块的超声波检查和细针穿刺分析提示为甲状腺癌。结论在资源有限的环境中,皮肌炎的早期诊断通常需要高度的临床怀疑,以防止不良后果的发生并识别相关的恶性肿瘤。
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引用次数: 0
HCV Reactivation in a Patient with Hepatocellular Carcinoma Due to Sorafenib: A Case Report 索拉非尼导致一名肝细胞癌患者的 HCV 再激活:病例报告
Pub Date : 2024-02-01 DOI: 10.2147/IMCRJ.S444521
Jun Cheng, Jinjin Pan, Dongmei Zhao, Xuejiao Ma, Qiulin Sun, Jiabin Li
Abstract The global prevalence of hepatitis C virus (HCV) infection is approximately 3%, with a post-infection chronicity rate of up to 50%–85%. HCV reactivation can occur when anti-HCV positive individuals receive antineoplastic therapy. In this study, we report a case of an anti-HCV positive patient with negative HCV RNA after 12 weeks of direct antiviral therapy. Two months later, sorafenib was used to treat hepatocellular carcinoma, and HCV reactivation occurred after 8 months of the treatment. HCV RNA was negative after 12 weeks of antiviral treatment with Sofosbuvir-velpatasvir. We also discussed the mechanism of HCV reactivation caused by sorafenib and the antiviral treatment regimen after HCV reactivation with the relevant literature.
摘要 全球丙型肝炎病毒(HCV)感染率约为 3%,感染后慢性化率高达 50%-85%。当抗-HCV 阳性者接受抗肿瘤治疗时,可能会发生 HCV 再激活。在本研究中,我们报告了一例抗-HCV 阳性患者在接受了 12 周的直接抗病毒治疗后,HCV RNA 为阴性。两个月后,患者使用索拉非尼治疗肝细胞癌,治疗 8 个月后出现 HCV 再激活。索非布韦-韦帕他韦抗病毒治疗 12 周后,HCV RNA 为阴性。我们还结合相关文献探讨了索拉非尼导致HCV再激活的机制以及HCV再激活后的抗病毒治疗方案。
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引用次数: 0
Minimally Invasive Resection of a Foraminal Lumbar Root Schwannoma 微创切除椎管内腰椎根部许旺瘤
Pub Date : 2024-02-01 DOI: 10.2147/IMCRJ.S445098
Chien-Ching Lee, Hao-Yu Chuang, C. Chang, Hung-Lin Lin, Cheng-Hsin Cheng
Background and Importance This video article reports a rare case of a right L5/S1 foraminal root schwannoma that presents the natural course of the disease, imaging findings, treatment protocol, operative procedure, and highlights some of the possible surgical complications. Clinical Presentation Magnetic resonance imaging (MRI) revealed an intradural, extramedullary, well-enhanced mass at the right L5/S1 level. The operative procedure involved a right minimal L5/S1 laminotomy/foraminotomy posteriorly to open the right L5 root. The facet joints were preserved to prevent spinal instability. The tumor was located along the root after opening the right L5/S1 foramen. Intraoperative electromyography (IOM) was conducted to detect any nerve injury in the patient. After opening the dura, the tumor was carefully separated from the normal root nerve under IOM monitoring. The mass was removed piece-by-piece using mini-forceps. Conclusion Histopathological examination confirmed the diagnosis of a schwannoma. The patient recovered without incident after surgery with minimal soreness and numbness in the right leg.
背景和重要性 这篇视频文章报道了一例罕见的右侧 L5/S1 腔根部裂孔瘤病例,介绍了该病的自然病程、影像学检查结果、治疗方案、手术过程,并强调了一些可能出现的手术并发症。临床表现 磁共振成像(MRI)显示右侧 L5/S1 水平有一个硬膜内、髓外、强化良好的肿块。手术过程包括右侧最小L5/S1椎板切除术/后方椎板切除术,以打开右侧L5根部。为防止脊柱不稳,手术保留了面关节。打开右侧L5/S1孔后,肿瘤沿着根部被找到。术中进行了肌电图(IOM)检查,以发现患者是否有神经损伤。打开硬脑膜后,在 IOM 监测下小心地将肿瘤与正常的根神经分离。用微型钳将肿块逐块切除。结论 组织病理学检查确诊为分裂瘤。患者术后恢复顺利,右腿疼痛和麻木症状轻微。
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引用次数: 0
Minimally Invasive Resection of a Foraminal Lumbar Root Schwannoma 微创切除椎管内腰椎根部许旺瘤
Pub Date : 2024-02-01 DOI: 10.2147/IMCRJ.S445098
Chien-Ching Lee, Hao-Yu Chuang, C. Chang, Hung-Lin Lin, Cheng-Hsin Cheng
Background and Importance This video article reports a rare case of a right L5/S1 foraminal root schwannoma that presents the natural course of the disease, imaging findings, treatment protocol, operative procedure, and highlights some of the possible surgical complications. Clinical Presentation Magnetic resonance imaging (MRI) revealed an intradural, extramedullary, well-enhanced mass at the right L5/S1 level. The operative procedure involved a right minimal L5/S1 laminotomy/foraminotomy posteriorly to open the right L5 root. The facet joints were preserved to prevent spinal instability. The tumor was located along the root after opening the right L5/S1 foramen. Intraoperative electromyography (IOM) was conducted to detect any nerve injury in the patient. After opening the dura, the tumor was carefully separated from the normal root nerve under IOM monitoring. The mass was removed piece-by-piece using mini-forceps. Conclusion Histopathological examination confirmed the diagnosis of a schwannoma. The patient recovered without incident after surgery with minimal soreness and numbness in the right leg.
背景和重要性 这篇视频文章报道了一例罕见的右侧 L5/S1 腔根部裂孔瘤病例,介绍了该病的自然病程、影像学检查结果、治疗方案、手术过程,并强调了一些可能出现的手术并发症。临床表现 磁共振成像(MRI)显示右侧 L5/S1 水平有一个硬膜内、髓外、强化良好的肿块。手术过程包括右侧最小L5/S1椎板切除术/后方椎板切除术,以打开右侧L5根部。为防止脊柱不稳,手术保留了面关节。打开右侧L5/S1孔后,肿瘤沿着根部被找到。术中进行了肌电图(IOM)检查,以发现患者是否有神经损伤。打开硬脑膜后,在 IOM 监测下小心地将肿瘤与正常的根神经分离。用微型钳将肿块逐块切除。结论 组织病理学检查确诊为分裂瘤。患者术后恢复顺利,右腿疼痛和麻木症状轻微。
{"title":"Minimally Invasive Resection of a Foraminal Lumbar Root Schwannoma","authors":"Chien-Ching Lee, Hao-Yu Chuang, C. Chang, Hung-Lin Lin, Cheng-Hsin Cheng","doi":"10.2147/IMCRJ.S445098","DOIUrl":"https://doi.org/10.2147/IMCRJ.S445098","url":null,"abstract":"Background and Importance This video article reports a rare case of a right L5/S1 foraminal root schwannoma that presents the natural course of the disease, imaging findings, treatment protocol, operative procedure, and highlights some of the possible surgical complications. Clinical Presentation Magnetic resonance imaging (MRI) revealed an intradural, extramedullary, well-enhanced mass at the right L5/S1 level. The operative procedure involved a right minimal L5/S1 laminotomy/foraminotomy posteriorly to open the right L5 root. The facet joints were preserved to prevent spinal instability. The tumor was located along the root after opening the right L5/S1 foramen. Intraoperative electromyography (IOM) was conducted to detect any nerve injury in the patient. After opening the dura, the tumor was carefully separated from the normal root nerve under IOM monitoring. The mass was removed piece-by-piece using mini-forceps. Conclusion Histopathological examination confirmed the diagnosis of a schwannoma. The patient recovered without incident after surgery with minimal soreness and numbness in the right leg.","PeriodicalId":508214,"journal":{"name":"International Medical Case Reports Journal","volume":"44 2","pages":"125 - 129"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139880887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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International Medical Case Reports Journal
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