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Comparison of Short-Term Outcomes Following Surgical Intervention of Salivary Gland Malignancies in Adult and Pediatric Patients: A National Database Analysis 成人和儿童唾液腺恶性肿瘤手术干预后短期疗效的比较:全国数据库分析
Pub Date : 2024-03-27 DOI: 10.1177/27325016241241826
Victor J. Yu, Aseela Samsam, Rajendra Sawh-Martinez, Joseph Lopez
Salivary gland malignancy (SGM) is a rare surgical pathology in the pediatric population, with currently ambiguous surgical management guidelines for the pediatric population. Therefore, we aim to use a national database to provide demographical and episode-of-care comparisons between the adult and pediatric population suffering from SGMs, with the interest of discovering baseline characteristic differences and outcomes, in addition to assessing the overall level of reporting at a national scale. The 2012 to 2019 American College of Surgeons’ National Surgical Quality Improvement Program Adult and Pediatric (ACS NSQIP, NSQIP-P) databases were queried to identify diagnoses of salivary gland malignancies based on postoperative ICD-10 codes. Age was stratified into adult (age ≥ 22 years) or pediatric (age < 22 years). Each age-based cohort were further stratified based on cancer site. Demographics, comorbidities, and complications were compared between adults and children. Overall, 1967 adult and 67 pediatric cases were included. Parotid gland malignancy comprised the majority of both adult and pediatric cases. Within cases of parotid gland malignancies, there were proportionally more adult compared to pediatric males. A lower comorbidity burden was also noted across pediatric cases. Operative time was slightly lower for pediatric cases compared to adult, with roughly 1 day less of total hospital stay. Complication rates were similar between adult and pediatric cases without statistically significant difference. Documentation of surgical outcomes in children with SGMs is severely lacking and continued reporting is imperative in order to improve outcomes of both oncologic and necessary reconstructive surgery. Optimal management of pediatric SGM demands use of a longitudinal multidisciplinary approach by surgeons cross-trained in head and neck surgery and plastic surgery. This is a burgeoning field with a need for studies aimed at developing guidelines specific for children.
唾液腺恶性肿瘤(SGM)是儿科中一种罕见的外科病变,目前儿科的手术治疗指南尚不明确。因此,我们旨在利用一个全国性数据库,对成人和儿科 SGM 患者的人口统计学和护理发作进行比较,以发现基线特征差异和结果,并评估全国范围内的总体报告水平。我们查询了 2012 年至 2019 年美国外科医生学会国家外科质量改进计划成人和儿科(ACS NSQIP、NSQIP-P)数据库,根据术后 ICD-10 编码确定唾液腺恶性肿瘤的诊断。年龄分为成人(年龄≥ 22 岁)和儿童(年龄< 22 岁)。每个年龄组又根据癌症部位进行分层。对成人和儿童的人口统计学、合并症和并发症进行了比较。总共纳入了 1967 例成人病例和 67 例儿童病例。腮腺恶性肿瘤占成人和儿童病例的大多数。在腮腺恶性肿瘤病例中,成人男性比例高于儿童。儿科病例的合并症负担也较低。儿科病例的手术时间略低于成人病例,住院总时间大约少1天。成人和儿科病例的并发症发生率相似,但无明显统计学差异。有关儿童 SGM 手术疗效的文献资料严重缺乏,为了提高肿瘤和必要的重建手术的疗效,继续报告势在必行。小儿 SGM 的最佳治疗方法要求接受过头颈外科和整形外科交叉培训的外科医生采用纵向多学科方法。这是一个方兴未艾的领域,需要开展研究以制定专门针对儿童的指南。
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引用次数: 0
A Review of Temporomandibular Joint (TMJ) Synovitis and the Important Role of the Nuclear Protein, High Mobility Group Box 1 (HMGB1) 颞下颌关节 (TMJ) 滑膜炎与核蛋白高迁移率基团框 1 (HMGB1) 的重要作用综述
Pub Date : 2024-03-27 DOI: 10.1177/27325016241235621
Vince DiFabio, Eman Mirdamadi, Sangyoon Kim
Studies identifying TMJ synovitis biomarkers are few and far between. During the late 1990s, Chuck Milam’s oxidative stress and re-perfusion models elucidated the molecular mechanisms of TMJ synovitis which centrally involves the cytokines TNF-α, IL-1β, and IL-6. However, a new understanding of TMJ synovitis has been developed given the fields current knowledge on pattern recognition receptors (PRRs), damageassociated molecular patterns (DAMPs), pathogen-associated molecular patterns (PAMPs) and most notably, high mobility group box 1 (HMGB1). Among these molecular markers, the oxidation of HMGB1 plays a key role in promoting pathological inflammation. In this perspective, we explore the role of HMGB1 during TMJ synovitis and how a traumatized TMJ responds to different HMGB1 post translational modifications (PTMs). Specifically, synovial inflammation will be explored in the context of how different PTMs of HMGB1 directs leukocytes to produce chemokines or cytokines. We will also look at the different modifications of HMGB1 molecule via Reduction Oxygenation Reactions. These recently identified mechanisms provide a suitable addition to the currently understood molecular actions of TMJ synovitis noted by Milam and others in the late 1990s and early 2000s. We will then conclude with a discussion on the use of antibodies to the HMGB1 molecule for a variety of conditions: cancers, sepsis, liver disease, traumatic brain injuries and early intervention for joint synovitis along with the use of different delivery modalities.
确定颞下颌关节滑膜炎生物标志物的研究少之又少。20 世纪 90 年代末,查克-米拉姆(Chuck Milam)的氧化应激和再灌注模型阐明了颞下颌关节滑膜炎的分子机制,其中主要涉及细胞因子 TNF-α、IL-1β 和 IL-6。然而,随着人们对模式识别受体(PRRs)、损伤相关分子模式(DAMPs)、病原体相关分子模式(PAMPs)以及最显著的高迁移率基团框 1(HMGB1)的了解,人们对颞下颌关节滑膜炎有了新的认识。在这些分子标记中,HMGB1 的氧化在促进病理炎症中起着关键作用。从这个角度出发,我们将探讨 HMGB1 在颞下颌关节滑膜炎中的作用,以及受到创伤的颞下颌关节如何对不同的 HMGB1 转化后修饰 (PTM) 作出反应。具体来说,我们将从 HMGB1 的不同 PTM 如何引导白细胞产生趋化因子或细胞因子的角度来探讨滑膜炎症。我们还将研究通过还原氧化反应对 HMGB1 分子进行的不同修饰。这些最新发现的机制为 Milam 等人在 20 世纪 90 年代末和 21 世纪初指出的颞下颌关节滑膜炎分子作用提供了适当的补充。最后,我们将讨论 HMGB1 分子抗体在多种疾病中的应用:癌症、败血症、肝病、脑外伤和关节滑膜炎的早期干预,以及不同给药方式的使用。
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引用次数: 0
Autologous Fat Transfer in Craniofacial Surgery 颅颌面手术中的自体脂肪移植
Pub Date : 2024-03-11 DOI: 10.1177/27325016241238441
Tatevik Malisetyan, Joshua L. Harrison, S. Shahriari, Tegan N. Clarke, Elizaveta V. Rogol, Gregory L. Borah
Over the past two decades, autologous fat transfer has garnered significant recognition and widespread adoption within esthetic and reconstructive surgical domains. In craniofacial surgery, fat transplantation is frequently employed to address soft tissue volumetric deficiencies and asymmetries that influence facial contours. While adipose tissue (AT) is widely regarded as an optimal choice for augmentation due to its abundant availability and biocompatibility, the unpredictability and heightened resorption rates observed with traditional lipofilling techniques present a challenge for clinicians. Adipose-derived stem cells (ASCs) housed within the grafted tissue play a pivotal role in graft survival and offer avenues for tissue repair due to their angiogenic, anti-inflammatory, and immunosuppressive properties. Micro Fragmentation of Adipose Tissue (MFAT), utilized in several FDA-approved processing devices, has demonstrated promising outcomes in treating osteoarthritic joints, with success primarily attributed to enhanced paracrine function of ASCs via preservation of the perivascular niche. Currently, its application for treating bone or articular defects in the craniofacial region, including abnormalities of the temporomandibular joint, remains limited. This scarcity underscores the need for further investigation prior to its widespread integration into clinical practice.
在过去的二十年里,自体脂肪移植在美容和整形外科领域获得了广泛的认可和采用。在颅面部手术中,脂肪移植经常被用来解决影响面部轮廓的软组织体积不足和不对称问题。虽然脂肪组织(AT)因其丰富的可用性和生物相容性而被广泛认为是增量的最佳选择,但传统脂肪填充技术的不可预测性和较高的吸收率给临床医生带来了挑战。移植组织中的脂肪源性干细胞(ASCs)因其血管生成、抗炎和免疫抑制特性,在移植存活中发挥着关键作用,并为组织修复提供了途径。美国食品和药物管理局(FDA)批准的几种加工设备都采用了脂肪组织微碎裂技术(MFAT),该技术在治疗骨关节炎方面取得了可喜的成果,其成功主要归功于通过保留血管周围龛位增强了间充质干细胞的旁分泌功能。目前,该技术在治疗颅面部骨骼或关节缺损(包括颞下颌关节异常)方面的应用仍然有限。这种稀缺性凸显了在将其广泛应用于临床实践之前进行进一步研究的必要性。
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引用次数: 0
Establishing a Resident-Driven Three-Dimensional Printing Lab Within an Academic Institution 在学术机构内建立居民驱动的三维打印实验室
Pub Date : 2024-02-28 DOI: 10.1177/27325016241234043
Srdjan Kamenko, Elizabeth Shepard, Andrew M. Ferry, Brynn A. Hathaway, Jens U. Berli, Reid V. Mueller
Three-dimensional (3D) modeling and printing technologies have been increasingly used throughout healthcare for research, educational, and clinical purposes. Despite the benefits associated with their use in surgical training, the literature poorly outlines the value of establishing an in-house, resident-driven 3D printing lab. Herein, we outline our quantifiable experience with our 3D printing lab and outline all necessary components needed to establish a lab such that the reader can replicate our experience at their institution. Additionally, we outline the process of creating a 3D-printed model from patient imaging with supplementary tutorial videos. A retrospective review of all 3D-printed models created in our in-house 3D printing lab since its creation in 2022 was performed. 3D-printed models that were utilized for formal educational or clinical purposes were included in this study. All 3D-printed models were created using the Raise3D 2 Pro. Cost estimates associated with each print were collected from the printer’s cost estimation function. A total of 14 3D-printed models met the inclusion criteria for our study. Of these, 4 (28.6%) were utilized for patient and/or resident education with the remaining 10 (71.4%) being used in patient care. By and large, the average cost of educational 3D-printed models was greater than clinical models ($12.00 vs $1.50, respectively). Ten 3D-printed models of mandibular fractures were successfully used to pre-bend plates prior to reconstructive surgery, and minimal intraoperative adjustment of the plate was required for each case. The processes of establishing a 3D printing lab along with creating a 3D-printed model from patient imaging are outlined. Establishing a 3D printing lab is an attainable feat for most institutions. High-value clinical and educational tools can be created for a reasonable price once the initial overhead costs of establishing a lab are covered.
三维(3D)建模和打印技术已越来越多地用于医疗保健领域的研究、教育和临床目的。尽管三维建模和打印技术在外科培训中的应用带来了诸多益处,但文献中对建立一个由住院医师主导的内部三维打印实验室的价值却缺乏概述。在此,我们概述了我们的 3D 打印实验室的量化经验,并概述了建立实验室所需的所有必要组件,以便读者可以在自己的机构复制我们的经验。此外,我们还通过辅助教学视频概述了根据患者成像创建 3D 打印模型的过程。我们对自 2022 年内部三维打印实验室成立以来创建的所有三维打印模型进行了回顾性审查。本研究包括用于正式教育或临床目的的三维打印模型。所有 3D 打印模型均使用 Raise3D 2 Pro 创建。打印机的成本估算功能收集了每次打印的相关成本估算。共有 14 个 3D 打印模型符合我们的研究纳入标准。其中 4 个(28.6%)用于患者和/或住院医师教育,其余 10 个(71.4%)用于患者护理。总体而言,教育用 3D 打印模型的平均成本高于临床模型(分别为 12.00 美元和 1.50 美元)。10 个下颌骨骨折的 3D 打印模型被成功用于重建手术前的钢板预弯,每个病例都只需要在术中对钢板进行最小程度的调整。本文概述了建立三维打印实验室以及根据患者图像创建三维打印模型的过程。对于大多数医疗机构来说,建立 3D 打印实验室是一项可以实现的壮举。只要支付了建立实验室的初期管理费用,就能以合理的价格制作出高价值的临床和教育工具。
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引用次数: 0
Evaluation of Head Height After Endoscopic Strip Craniectomy and Orthotic Therapy for Sagittal Craniosynostosis 矢状颅畸形内窥镜带状颅骨切除术和矫形治疗后的头高评估
Pub Date : 2024-02-19 DOI: 10.1177/27325016241233754
Andrew D. Linkugel, Gary B. Skolnick, Sybill D. Naidoo, Matthew D. Smyth, Kamlesh Patel
Achievement of normal head shape is one of the primary goals of all treatment modalities for craniosynostosis, in addition to maintenance of normal intracranial pressure and allowing normal brain development. Pre- and postoperative quantification of head shape in sagittal craniosynostosis has largely relied on cephalic index (width divided by anterior-posterior length of skull). However, many infants with sagittal craniosynostosis have a head that is short in addition to long and narrow. Height is not captured by the cephalic index. Patients who underwent endoscopic repair of sagittal craniosynostosis between 2016 and 2019 with available pre- and 1-year postoperative head computed tomography (CT) scans were identified. Age-matched controls with available CT scans were used for comparison. Twenty-one patients with sagittal craniosynostosis who underwent endoscopic repair, 10 preoperative, and 10 postoperative age-matched controls were identified. CT scans were measured with Analyze 12.0 software using soft tissue windows. Head height was defined as the vertical distance from the opisthocranion to the top of the head along a line crossing the tragus. Patients with sagittal craniosynostosis had a shorter head height (mean 6.01 cm) than age-matched controls (mean 6.94 cm, P = .0003), and, after endoscopic repair and helmeting, the head height (mean 8.05 cm) was similar to age matched controls (mean 8.22 cm, P = .515). This head height measurement quantifies the third dimension of abnormal head shape in sagittal craniosynostosis. Additionally, it is adequately corrected in endoscopic repair with helmeting.
除了维持正常的颅内压和允许大脑正常发育外,实现正常头型是所有颅脑发育畸形治疗方法的主要目标之一。矢状颅畸形术前和术后头型的量化主要依靠头颅指数(头颅宽度除以头颅前后长度)。然而,许多矢状颅畸形婴儿的头部除了狭长外,还很矮。头颅指数不能反映身高。研究人员确定了在 2016 年至 2019 年期间接受内窥镜修复矢状颅畸形并提供术前和术后 1 年头部计算机断层扫描(CT)的患者。与年龄相匹配且有 CT 扫描结果的对照组进行比较。确定了 21 名接受内窥镜修复的矢状颅畸形患者、10 名术前对照组和 10 名术后年龄匹配对照组。使用 Analyze 12.0 软件的软组织窗口对 CT 扫描进行测量。头高的定义是从颅骨外侧到头顶的垂直距离,沿一条线穿过颅骨外侧。矢状颅畸形患者的头高(平均 6.01 厘米)短于年龄匹配的对照组(平均 6.94 厘米,P = 0.0003),而经过内窥镜修复和戴头盔后,患者的头高(平均 8.05 厘米)与年龄匹配的对照组(平均 8.22 厘米,P = 0.515)相似。这种头高测量方法可量化矢状颅畸形患者头型异常的第三个维度。此外,在内窥镜修复术中,头盔也能对其进行适当矫正。
{"title":"Evaluation of Head Height After Endoscopic Strip Craniectomy and Orthotic Therapy for Sagittal Craniosynostosis","authors":"Andrew D. Linkugel, Gary B. Skolnick, Sybill D. Naidoo, Matthew D. Smyth, Kamlesh Patel","doi":"10.1177/27325016241233754","DOIUrl":"https://doi.org/10.1177/27325016241233754","url":null,"abstract":"Achievement of normal head shape is one of the primary goals of all treatment modalities for craniosynostosis, in addition to maintenance of normal intracranial pressure and allowing normal brain development. Pre- and postoperative quantification of head shape in sagittal craniosynostosis has largely relied on cephalic index (width divided by anterior-posterior length of skull). However, many infants with sagittal craniosynostosis have a head that is short in addition to long and narrow. Height is not captured by the cephalic index. Patients who underwent endoscopic repair of sagittal craniosynostosis between 2016 and 2019 with available pre- and 1-year postoperative head computed tomography (CT) scans were identified. Age-matched controls with available CT scans were used for comparison. Twenty-one patients with sagittal craniosynostosis who underwent endoscopic repair, 10 preoperative, and 10 postoperative age-matched controls were identified. CT scans were measured with Analyze 12.0 software using soft tissue windows. Head height was defined as the vertical distance from the opisthocranion to the top of the head along a line crossing the tragus. Patients with sagittal craniosynostosis had a shorter head height (mean 6.01 cm) than age-matched controls (mean 6.94 cm, P = .0003), and, after endoscopic repair and helmeting, the head height (mean 8.05 cm) was similar to age matched controls (mean 8.22 cm, P = .515). This head height measurement quantifies the third dimension of abnormal head shape in sagittal craniosynostosis. Additionally, it is adequately corrected in endoscopic repair with helmeting.","PeriodicalId":508736,"journal":{"name":"FACE","volume":"47 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140452307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Branchial Arch Remnants in the Pediatric Patient Under Local Anesthesia 局部麻醉下小儿患者的腮弓残留物
Pub Date : 2024-02-19 DOI: 10.1177/27325016241232713
S. Othman, Nissim Hazkour, Jose Palacios, Nicholas Bastidas
Objective: Branchial arch remnants are a well-encountered pathology in pediatric patients. In the majority of cases, these vestiges are superficial and benign, save for minor cosmetic deformity or discomfort. Although branchial arch remnants in the form of skin vestiges are commonly removed, there remains a lack of in-depth study regarding appropriate protocol and experience under local anesthesia. Design: A retrospective review of subjects undergoing first branchial arch vestige excision utilizing local anesthesia was conducted (2017-2021). Demographics were recorded, including age, sex, comorbidities, vestige location, presence of tracts, post-operative complications, and significant associations. Results: A total of 178 subjects were identified for inclusion. The mean patient age during the procedure was 18.4 ± 38.3 months. A total of 34 patients presented with a current or prior comorbidity (24.7%). The most common location of the branchial remnant was the preauricular region (79.2%). Most patients were without complication (96.1%). Secondarily developed branchial anomalies were significantly associated with complications as compared to congenital anomalies (22.2% vs 3.0%, P < .042). Additionally, patients with a past medical history were significantly more likely to develop a post-operative complication (71.4% vs 22.6%, P < .13). Conclusion: In-office branchial remnant removal is a safe procedure in the young pediatric patient. Complication rates are low; patients with a significant past medical history may be more likely to incur postoperative complications. Additionally, patients with secondary vestige development may also be more likely to develop complications. Further in-office procedures are encouraged.
目的:腮弓残余是儿童患者中经常遇到的一种病理现象。在大多数病例中,这些残余都是浅表性的良性病变,仅有轻微的外观畸形或不适。虽然皮肤残基形式的腮弓残留物通常会被切除,但关于局部麻醉下的适当方案和经验仍缺乏深入研究。设计:对首次使用局部麻醉进行杈弓残迹切除术的受试者进行回顾性研究(2017-2021 年)。记录了人口统计学特征,包括年龄、性别、合并症、残基位置、有无束带、术后并发症和重要关联。结果:共确定了 178 名纳入对象。手术期间患者的平均年龄为(18.4 ± 38.3)个月。共有 34 名患者目前或之前患有合并症(24.7%)。耳前区域是最常见的残余腮腺位置(79.2%)。大多数患者没有并发症(96.1%)。与先天性畸形相比,后天形成的腮腺畸形与并发症有显著相关性(22.2% vs 3.0%,P < .042)。此外,有既往病史的患者发生术后并发症的几率明显更高(71.4% vs 22.6%,P < .13)。结论对于年轻的儿科患者来说,诊室内残余腮腺切除术是一种安全的手术。并发症发生率较低;有严重既往病史的患者可能更容易出现术后并发症。此外,有继发性残迹的患者也更容易出现并发症。我们鼓励更多的诊室内手术。
{"title":"Branchial Arch Remnants in the Pediatric Patient Under Local Anesthesia","authors":"S. Othman, Nissim Hazkour, Jose Palacios, Nicholas Bastidas","doi":"10.1177/27325016241232713","DOIUrl":"https://doi.org/10.1177/27325016241232713","url":null,"abstract":"Objective: Branchial arch remnants are a well-encountered pathology in pediatric patients. In the majority of cases, these vestiges are superficial and benign, save for minor cosmetic deformity or discomfort. Although branchial arch remnants in the form of skin vestiges are commonly removed, there remains a lack of in-depth study regarding appropriate protocol and experience under local anesthesia. Design: A retrospective review of subjects undergoing first branchial arch vestige excision utilizing local anesthesia was conducted (2017-2021). Demographics were recorded, including age, sex, comorbidities, vestige location, presence of tracts, post-operative complications, and significant associations. Results: A total of 178 subjects were identified for inclusion. The mean patient age during the procedure was 18.4 ± 38.3 months. A total of 34 patients presented with a current or prior comorbidity (24.7%). The most common location of the branchial remnant was the preauricular region (79.2%). Most patients were without complication (96.1%). Secondarily developed branchial anomalies were significantly associated with complications as compared to congenital anomalies (22.2% vs 3.0%, P < .042). Additionally, patients with a past medical history were significantly more likely to develop a post-operative complication (71.4% vs 22.6%, P < .13). Conclusion: In-office branchial remnant removal is a safe procedure in the young pediatric patient. Complication rates are low; patients with a significant past medical history may be more likely to incur postoperative complications. Additionally, patients with secondary vestige development may also be more likely to develop complications. Further in-office procedures are encouraged.","PeriodicalId":508736,"journal":{"name":"FACE","volume":"25 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140450610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scalp and Dural Reconstruction With a Tensor Fascia Lata Myofascial and Anterolateral Thigh Fasciocutaneous Chimeric Flap: A Case Report 用张肌筋膜和大腿前外侧筋膜皮嵌合瓣重建头皮和硬脑膜:病例报告
Pub Date : 2024-02-15 DOI: 10.1177/27325016241232822
Kristen S. Whalen, Sarah Moffitt, Nicole K. Le, Jared S. Troy
Composite scalp and cranial defects present a challenge due to the unique elements that need to be reconstructed. The goals of reconstruction are to protect intracranial contents, prevent cerebrospinal fluid leak (CSF) and infection, and to provide durable soft tissue coverage. We present a case of an immunocompromised patient with history of craniotomy who developed osteomyelitis and a cranial abscess resulting in a composite defect with dural, bony, and soft tissue loss. To achieve vascularized watertight dural repair and durable soft tissue coverage for resolution of infection and eventual staged cranioplasty, we performed a free tensor fascia lata (TFL) myofascial and anterolateral thigh (ALT) fasciocutaneous chimeric flap. The patient healed well without CSF leak or infection at 5-month follow-up and cranioplasty is planned. Use of a chimeric TFL and ALT flap is effective in the treatment of large, composite cranial defects in the setting of active infection.
复合头皮和颅骨缺损是一项挑战,因为需要重建的元素非常独特。重建的目的是保护颅内内容物,防止脑脊液漏(CSF)和感染,并提供持久的软组织覆盖。我们介绍了一例有开颅手术史的免疫功能低下患者的病例,该患者出现骨髓炎和颅内脓肿,导致硬脑膜、骨和软组织缺损的复合缺损。为了实现血管化不漏水硬膜修复和持久的软组织覆盖,以解决感染并最终进行分期颅骨成形术,我们进行了游离张肌筋膜(TFL)肌筋膜瓣和大腿前外侧(ALT)筋膜瓣嵌合。随访5个月时,患者愈合良好,无脑脊液渗漏或感染,并计划进行头颅成形术。使用TFL和ALT嵌合皮瓣可以有效治疗活动性感染情况下的大面积复合颅骨缺损。
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引用次数: 0
Scalp and Dural Reconstruction With a Tensor Fascia Lata Myofascial and Anterolateral Thigh Fasciocutaneous Chimeric Flap: A Case Report 用张肌筋膜和大腿前外侧筋膜皮嵌合瓣重建头皮和硬脑膜:病例报告
Pub Date : 2024-02-15 DOI: 10.1177/27325016241232822
Kristen S. Whalen, Sarah Moffitt, Nicole K. Le, Jared S. Troy
Composite scalp and cranial defects present a challenge due to the unique elements that need to be reconstructed. The goals of reconstruction are to protect intracranial contents, prevent cerebrospinal fluid leak (CSF) and infection, and to provide durable soft tissue coverage. We present a case of an immunocompromised patient with history of craniotomy who developed osteomyelitis and a cranial abscess resulting in a composite defect with dural, bony, and soft tissue loss. To achieve vascularized watertight dural repair and durable soft tissue coverage for resolution of infection and eventual staged cranioplasty, we performed a free tensor fascia lata (TFL) myofascial and anterolateral thigh (ALT) fasciocutaneous chimeric flap. The patient healed well without CSF leak or infection at 5-month follow-up and cranioplasty is planned. Use of a chimeric TFL and ALT flap is effective in the treatment of large, composite cranial defects in the setting of active infection.
复合头皮和颅骨缺损是一项挑战,因为需要重建的元素非常独特。重建的目的是保护颅内内容物,防止脑脊液漏(CSF)和感染,并提供持久的软组织覆盖。我们介绍了一例有开颅手术史的免疫功能低下患者的病例,该患者出现骨髓炎和颅内脓肿,导致硬脑膜、骨和软组织缺损的复合缺损。为了实现血管化不漏水硬膜修复和持久的软组织覆盖,以解决感染并最终进行分期颅骨成形术,我们进行了游离张肌筋膜(TFL)肌筋膜瓣和大腿前外侧(ALT)筋膜瓣嵌合。随访5个月时,患者愈合良好,无脑脊液渗漏或感染,并计划进行头颅成形术。使用TFL和ALT嵌合皮瓣可以有效治疗活动性感染情况下的大面积复合颅骨缺损。
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引用次数: 0
The Sonopet iQ® Ultrasonic Bone Aspirator in Craniofacial Surgery: A Scoping Review and Qualitative Analysis 颅颌面手术中的 Sonopet iQ® 超声骨抽吸器:范围审查和定性分析
Pub Date : 2024-02-10 DOI: 10.1177/27325016241230672
Gwendolyn E. Daly, Rebecca A. Luh, Darius Balumuka, Lori K. Howell, Erik M. Wolfswinkel
The Sonopet iQ® Ultrasonic Aspirator is a surgical tool used for the fragmentation and emulsification of bone and soft tissue. Ultrasonic vibrations emulsify bone with cited benefits of decreased damage to surrounding soft tissue and minimal heat dispersion. Despite these potential benefits, there is a paucity of published articles on the safety and efficacy of the Sonopet® in the setting of craniofacial surgery. In accordance with PRISMA guidelines, MEDLINE and Pubmed were searched for articles that studied use of the Sonopet® for osteotomies in the craniofacial setting. Studies exclusively investigating soft tissue aspiration were excluded. Out of 61 articles discovered, 22 met inclusion criteria and discussed a total of 816 patients. Of the 22 articles, there were 8 retrospective chart reviews, 7 case series, 5 cadaver models, and 2 case reports. Studies spanned multiple disciplines including otolaryngology, ophthalmology, craniofacial surgery, neurosurgery, and oral and maxillofacial surgery. Despite its frequent use in orthognathic and cranial vault remodeling surgery, only 4 studies described its use in these fields. The most commonly cited benefits of the Sonopet® were enhanced ergonomics and safety, discussed in 20 of the included studies. Eighteen studies claimed the Sonopet® was safer to use in surgically tight spaces compared to traditional drills. Four studies found decreased bone dust generation by the Sonopet® compared to conventional cutting devices. No studies reported an increase in postoperative complications due to the device. The most commonly cited disadvantage was the cost of the device, however, the majority of authors believed the benefits of the device outweighed the increase in cost. There is a dearth of research investigating the use of the Sonopet® in craniofacial surgery. Available studies emphasize the ergonomic and safety benefits of the Sonopet® and encourage expanded use of the device despite its cost.
Sonopet iQ® 超声波抽吸器是一种用于破碎和乳化骨骼和软组织的手术工具。超声波振动可乳化骨骼,其优点是减少对周围软组织的损伤,并将热扩散降至最低。尽管有这些潜在的优点,但有关 Sonopet® 在颅面手术中的安全性和有效性的发表文章却很少。根据 PRISMA 指南,我们在 MEDLINE 和 Pubmed 上搜索了研究在颅面手术中使用 Sonopet® 进行截骨的文章。排除了专门研究软组织抽吸的文章。在发现的 61 篇文章中,22 篇符合纳入标准,共讨论了 816 名患者。在这 22 篇文章中,有 8 篇回顾性病历评论、7 篇系列病例、5 篇尸体模型和 2 篇病例报告。研究涉及多个学科,包括耳鼻喉科、眼科、颅面外科、神经外科以及口腔颌面外科。尽管在正颌和颅顶重塑手术中经常使用,但只有 4 项研究描述了它在这些领域的应用。Sonopet®最常被提及的优点是提高了工效学和安全性,有20项研究对此进行了讨论。18 项研究称,与传统钻头相比,Sonopet® 在狭小的手术空间中使用更安全。四项研究发现,与传统切割设备相比,Sonopet® 减少了骨粉的产生。没有研究报告称该设备会增加术后并发症。最常提到的缺点是该设备的成本,但大多数作者认为该设备的优点超过了成本的增加。关于在颅颌面手术中使用 Sonopet® 的研究还很缺乏。现有研究强调了 Sonopet® 在人体工程学和安全性方面的优势,并鼓励扩大该设备的使用范围,尽管其成本较高。
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引用次数: 0
The Sonopet iQ® Ultrasonic Bone Aspirator in Craniofacial Surgery: A Scoping Review and Qualitative Analysis 颅颌面手术中的 Sonopet iQ® 超声骨抽吸器:范围审查和定性分析
Pub Date : 2024-02-10 DOI: 10.1177/27325016241230672
Gwendolyn E. Daly, Rebecca A. Luh, Darius Balumuka, Lori K. Howell, Erik M. Wolfswinkel
The Sonopet iQ® Ultrasonic Aspirator is a surgical tool used for the fragmentation and emulsification of bone and soft tissue. Ultrasonic vibrations emulsify bone with cited benefits of decreased damage to surrounding soft tissue and minimal heat dispersion. Despite these potential benefits, there is a paucity of published articles on the safety and efficacy of the Sonopet® in the setting of craniofacial surgery. In accordance with PRISMA guidelines, MEDLINE and Pubmed were searched for articles that studied use of the Sonopet® for osteotomies in the craniofacial setting. Studies exclusively investigating soft tissue aspiration were excluded. Out of 61 articles discovered, 22 met inclusion criteria and discussed a total of 816 patients. Of the 22 articles, there were 8 retrospective chart reviews, 7 case series, 5 cadaver models, and 2 case reports. Studies spanned multiple disciplines including otolaryngology, ophthalmology, craniofacial surgery, neurosurgery, and oral and maxillofacial surgery. Despite its frequent use in orthognathic and cranial vault remodeling surgery, only 4 studies described its use in these fields. The most commonly cited benefits of the Sonopet® were enhanced ergonomics and safety, discussed in 20 of the included studies. Eighteen studies claimed the Sonopet® was safer to use in surgically tight spaces compared to traditional drills. Four studies found decreased bone dust generation by the Sonopet® compared to conventional cutting devices. No studies reported an increase in postoperative complications due to the device. The most commonly cited disadvantage was the cost of the device, however, the majority of authors believed the benefits of the device outweighed the increase in cost. There is a dearth of research investigating the use of the Sonopet® in craniofacial surgery. Available studies emphasize the ergonomic and safety benefits of the Sonopet® and encourage expanded use of the device despite its cost.
Sonopet iQ® 超声波抽吸器是一种用于破碎和乳化骨骼和软组织的手术工具。超声波振动可乳化骨骼,其优点是减少对周围软组织的损伤,并将热扩散降至最低。尽管有这些潜在的优点,但有关 Sonopet® 在颅面手术中的安全性和有效性的发表文章却很少。根据 PRISMA 指南,我们在 MEDLINE 和 Pubmed 上搜索了研究在颅面手术中使用 Sonopet® 进行截骨的文章。排除了专门研究软组织抽吸的文章。在发现的 61 篇文章中,22 篇符合纳入标准,共讨论了 816 名患者。在这 22 篇文章中,有 8 篇回顾性病历评论、7 篇系列病例、5 篇尸体模型和 2 篇病例报告。研究涉及多个学科,包括耳鼻喉科、眼科、颅面外科、神经外科以及口腔颌面外科。尽管在正颌和颅顶重塑手术中经常使用,但只有 4 项研究描述了它在这些领域的应用。Sonopet®最常被提及的优点是提高了工效学和安全性,有20项研究对此进行了讨论。18 项研究称,与传统钻头相比,Sonopet® 在狭小的手术空间中使用更安全。四项研究发现,与传统切割设备相比,Sonopet® 减少了骨粉的产生。没有研究报告称该设备会增加术后并发症。最常提到的缺点是该设备的成本,但大多数作者认为该设备的优点超过了成本的增加。关于在颅颌面手术中使用 Sonopet® 的研究还很缺乏。现有研究强调了 Sonopet® 在人体工程学和安全性方面的优势,并鼓励扩大该设备的使用范围,尽管其成本较高。
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