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Advantages of an Image-Guided Subcranial Technique for Le Fort III Osteotomies for Midface Advancement: A Case Series 图像引导下的颅下技术用于 Le Fort III 型中面推进截骨术的优势:病例系列
Pub Date : 2024-01-30 DOI: 10.1177/27325016241227446
Katherine G. Holste, Katelyn G. Makar, R. Ulma, H. J. Garton, S. Buchman, Christian J. Vercler, K. Muraszko
Le Fort III osteotomies are used to advance the midface in children with midface hypoplasia and syndromic craniosynostosis. Complications can occur during the subcranial osteotomies, leading todural violations as well as vascular and neurologic injuries. In patients with cerebrospinal fluid (CSF) shunts, CSF leak places them at risk of shunt infection. To avoid these injuries, surgeons may utilize an intracranial approach to gain optimal visualization of the cranial base for the horizontal cut through the ethmoid bone, at the naso-frontal junction, below the cribiform plate. A formal craniotomy to simply assure a safe osteotomy, however, may well be an unnecessary morbidity. The aim of this study was to describe the indications for and technical advantages of image guidance for subcranial Le Fort III osteotomies without a craniotomy. We describe the use of the StealthStation 3-D intraoperative image guidance system for subcranial Le Fort III osteotomies and associated clinical outcomes. An electronic medical record search at a single academic institution identified 10 patients with Current Procedural Terminology codes 21154-21155 (reconstruction midface, Le Fort III). Six patients underwent image-guided subcranial Le Fort III osteotomies between 2008 and 2023. There were no cases of vascular injury, cranial nerve injury, or cerebrospinal fluid leak. No patients with a CSF shunt experienced shunt infection during follow up. Image-guidance provides technical advantages as an alternative approach to subcranial Le Fort III osteotomies while allowing the surgeon to avoid the morbidity of a craniotomy.
Le Fort III 截骨术用于推进中面发育不良和综合颅畸形患儿的中面。颅下截骨术可能会发生并发症,导致硬脑膜损伤以及血管和神经损伤。在脑脊液(CSF)分流患者中,CSF 泄漏会使他们面临分流感染的风险。为了避免这些损伤,外科医生可能会采用颅内入路,以获得最佳的颅底视野,在鼻额交界处、楔形板下方的乙状骨上进行水平切开。然而,为了确保安全截骨而进行的正式开颅手术很可能会造成不必要的发病。本研究的目的是描述在不开颅的情况下进行颅下 Le Fort III 截骨术的图像引导的适应症和技术优势。我们描述了 StealthStation 3-D 术中图像引导系统在颅下 Le Fort III 截骨术中的应用及相关临床结果。通过对一家学术机构的电子病历进行搜索,我们发现了 10 位当前程序术语代码为 21154-21155(重建中面,Le Fort III)的患者。六名患者在 2008 年至 2023 年期间接受了图像引导下的颅下 Le Fort III 截骨术。无血管损伤、颅神经损伤或脑脊液漏病例。在随访期间,没有脑脊液分流患者发生分流感染。作为颅下 Le Fort III 截骨术的替代方法,图像引导具有技术优势,同时允许外科医生避免开颅手术的发病率。
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引用次数: 0
Revealing a Cleft in the Community: A Systematic Review of Sociodemographic Disparities Affecting the Care of Patients With Cleft Lip 在社区发现唇裂:影响唇裂患者护理的社会人口差异系统回顾
Pub Date : 2024-01-30 DOI: 10.1177/27325016241227614
Chioma G. Obinero, Alexandra Boyd, Jose E Barrera, Alyssa Valenti, Naikhoba C. O. Munabi, Thomas A. Imahiyerobo, M. Greives
Comprehensive management of cleft lip with or without cleft palate (CL/P) often begins prenatally, continues into adulthood, and involves multidisciplinary collaboration. This study aims to review the current literature and summarize sociodemographic disparities that impact access to care, management, and postoperative outcomes in patients with CL/P. A systematic review was conducted using Pubmed, Embase, and Medline databases. Studies discussing sociodemographic disparities regarding access to care, management, and treatment outcomes for patients with CL/P were included. Studies performed outside the US and published before the year 2000 were excluded. Of 3782 studies initially identified, 26 met the inclusion criteria. Disparities discussed included access to care (n = 11), missed appointments (n = 2), use of nasoalveolar molding [NAM] (n = 3), surgical timing (n = 8), and surgical outcomes (n = 8). Minority race or ethnicity, particularly black, Hispanic, Asian, and Native-American, as well as public insurance were associated with impaired access to care. Other factors causing impaired access to care were non-English primary language and high cost. Predictors for missed appointments were black race and Medicaid insurance. Decreased use of or success with NAM was associated with Asian race, public insurance, and long travel distance to a cleft care center. Factors associated with delayed CL surgery were Asian or black race, Hispanic ethnicity, public insurance, and non-English primary language. Surgical outcomes were assessed using various esthetic, speech, and quality of life measures; factors linked to worse outcomes included black or latin race and public insurance. Patients with CL/P from minority racial or ethnic groups, particularly black, Asian, and Hispanic, as well as those with public insurance are disproportionately impacted by health disparities. Disparities related to age, geographic location, and primary language have also been reported, among others. Statewide or institutional social programs may help address these disparities.
唇裂伴或不伴腭裂(CL/P)的综合治疗通常从产前开始,一直持续到成年,并涉及多学科协作。本研究旨在回顾现有文献,总结影响 CL/P 患者获得护理、管理和术后效果的社会人口差异。我们使用 Pubmed、Embase 和 Medline 数据库进行了系统性综述。纳入的研究讨论了 CL/P 患者在获得护理、管理和治疗效果方面的社会人口差异。排除了在美国以外进行的研究和 2000 年以前发表的研究。在最初确定的 3782 项研究中,有 26 项符合纳入标准。讨论的差异包括获得治疗的机会(11 例)、错过预约(2 例)、鼻齿槽成型[NAM]的使用(3 例)、手术时机(8 例)和手术结果(8 例)。少数种族或民族(尤其是黑人、西班牙裔、亚裔和美国本土人)以及公共保险与就医障碍有关。其他导致就医障碍的因素包括非英语母语和高额费用。错过预约的预测因素是黑人和医疗补助保险。使用 NAM 的减少或成功率的降低与亚裔、公共保险和前往唇裂护理中心的路途遥远有关。延迟 CL 手术的相关因素包括亚裔或黑人、西班牙裔、公共保险和非英语母语。手术效果通过各种美学、语言和生活质量指标进行评估;与较差的手术效果相关的因素包括黑人或拉丁种族以及公共保险。来自少数种族或民族群体(尤其是黑人、亚裔和西班牙裔)以及有公共保险的 CL/P 患者受到健康差异的影响尤为严重。与年龄、地理位置和主要语言等有关的差异也有报道。全州或机构的社会计划可能有助于解决这些差异。
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引用次数: 0
Mon Cher Tony: A Tribute to S. Anthony Wolfe, MD Mon Cher Tony:向 S. Anthony Wolfe 医生致敬
Pub Date : 2024-01-28 DOI: 10.1177/27325016241228873
Jordan P. Steinberg
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引用次数: 0
A Man From Miami 来自迈阿密的男人
Pub Date : 2024-01-28 DOI: 10.1177/27325016241229899
Bill Hoffman
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引用次数: 0
Independent, Determined, Caring: A Tribute to S. Tony Wolfe 独立、坚定、富有爱心:向托尼-沃尔夫致敬
Pub Date : 2024-01-28 DOI: 10.1177/27325016241229895
David Matthews
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引用次数: 0
Remembering Our Mentors: Paul Tessier, Ralph Millard, Tony Wolfe, Dave Matthews, Bill Hoffman, Reza Jarrahy, Joe Williams, Jordan Steinberg 缅怀我们的导师保罗-泰西尔、拉尔夫-米拉德、托尼-沃尔夫、戴夫-马修斯、比尔-霍夫曼、雷扎-贾拉希、乔-威廉姆斯、乔丹-斯坦伯格
Pub Date : 2024-01-28 DOI: 10.1177/27325016241229898
John van Aalst
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引用次数: 0
A Brief Self-Reflection of a Man and His Life: Anthony Wolfe 一个人及其一生的简短自述:安东尼-沃尔夫
Pub Date : 2024-01-28 DOI: 10.1177/27325016241229903
Tony Wolfe
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引用次数: 0
Giant Shoulders 巨肩
Pub Date : 2024-01-28 DOI: 10.1177/27325016241229900
Reza Jarrahy
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引用次数: 0
Is Botox or Dermabond Superior in the Appearance of the Lip Scar After Primary Cleft Lip Repair and Revision? A Systematic Review and Meta-Analysis 原发性唇裂修复和翻修术后唇部疤痕的外观是肉毒杆菌素更佳还是 Dermabond 更佳?系统回顾与元分析
Pub Date : 2024-01-25 DOI: 10.1177/27325016231226300
Paul F. Martinez, Theresa K. Webster, Thomas A. Imahiyerobo
Cleft lip scar formation is an inevitable consequence of cleft lip repair (CLR) and is exacerbated by the dynamic movement of the middle face. Various methods to correct or prevent these deformities have been described including silicone sheeting, surgical revisions, laser therapy, and more recently, Botulinum toxin-A (Botox) and Dermabond. This study aims to analyze and compare the impact of Botox versus Dermabond on scar appearance after CLR. Following PRISMA guidelines, a systematic review was performed on Medline, Embase, Cochrane, and CINAHL using the following keywords: “Dermabond,” “botulinum toxin,” and “cleft lip.” Outcomes of interest were the rates of scar hypertrophy, scar width, Vancouver scar scale (VSS), visual analog scale (VAS), Hollander wound evaluation scale (HWES), and complications. Nine studies were included of which 4 articles analyzed Botox and 5 analyzed Dermabond. Forest plots for scar width at the first and second time point supported the use of Botox to achieve a smaller scar width with P < .0001 (95% CI: −1.09 [−1.56 to −0.63] and 95% CI: −0.94 [−1.37 to −0.50], respectively). A significant increase in VAS was observed with Botox (95% CI: 1.66 [1.27-2.05], P value < .0001) and VSS was insignificant. Of the articles that analyzed Dermabond, scar appearance was comparable to the traditional suture closure group. There were no feeding complications for either intervention. Pooled forest plots for VAS comparing Botox and Dermabond supported the use of Botox with improved VAS (95% CI: 1.66 [1.27-2.05], P < .0001) compared to Dermabond (95% CI: 0.07 [ −0.48 to 0.61], P = .80). The current literature supports the use of Botox for scar improvement following CLR or revision. However, there is limited data to support Dermabond’s utility in improving scars in CLR, which highlights the need for further studies.
唇裂疤痕的形成是唇裂修复术(CLR)不可避免的后果,并因面部中部的动态运动而加剧。目前已有多种方法可纠正或预防这些畸形,包括硅胶薄片、手术修整、激光治疗,以及最近的 A 型肉毒杆菌毒素(Botox)和 Dermabond。本研究旨在分析和比较肉毒杆菌毒素和 Dermabond 对 CLR 后疤痕外观的影响。根据 PRISMA 指南,我们使用以下关键词在 Medline、Embase、Cochrane 和 CINAHL 上进行了系统性综述:"Dermabond"、"肉毒素 "和 "唇裂"。研究结果包括疤痕肥大率、疤痕宽度、温哥华疤痕量表(VSS)、视觉模拟量表(VAS)、霍兰德伤口评估量表(HWES)和并发症。共纳入了 9 项研究,其中 4 篇分析了肉毒杆菌毒素,5 篇分析了 Dermabond。第一和第二个时间点的疤痕宽度森林图显示,使用肉毒杆菌毒素可使疤痕宽度变小,P < .0001(95% CI:-1.09 [-1.56 to -0.63]和 95% CI:-0.94 [-1.37 to -0.50])。肉毒杆菌毒素可使 VAS 明显增加(95% CI:1.66 [1.27-2.05],P 值<.0001),而 VSS 则无明显增加。在分析 Dermabond 的文章中,疤痕外观与传统缝合组相当。两种干预方法均未出现进食并发症。比较肉毒杆菌毒素和 Dermabond 的 VAS 汇总森林图显示,与 Dermabond 相比,使用肉毒杆菌毒素可改善 VAS(95% CI:1.66 [1.27-2.05],P < .0001)(95% CI:0.07 [ -0.48 至 0.61],P = .80)。目前的文献支持使用肉毒杆菌毒素来改善 CLR 或翻修后的疤痕。然而,支持 Dermabond 用于改善 CLR 后疤痕的数据很有限,这就凸显了进一步研究的必要性。
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引用次数: 0
The Anatomy and Physiology of the Glymphatic System and Its Role in Craniectomies and Syndrome of the Trephined 淋巴系统的解剖学和生理学及其在颅骨切除术和锥体综合征中的作用
Pub Date : 2024-01-25 DOI: 10.1177/27325016231226301
Haley K. Talbot-Stetsko, Katherine G. Holste, Megan Dietze-Fiedler, Geoffrey E. Hespe, Christian J. Vercler, K. Muraszko
The glymphatic system, a relatively recently discovered system for transport of cerebrospinal fluid (CSF) and waste products in the central nervous system, has been implicated in several neurologic disorders. Altered CSF dynamics are seen after decompressive craniectomy, suggesting this procedure may impact glymphatic function. We aimed to systematically review the current literature to understand the effect of the glymphatic system on patients with decompressive craniectomies and Syndrome of the Trephined (SoT). PubMed and Embase were searched for preclinical and clinical studies investigating the glymphatic system and craniectomy, cranioplasty, or SoT in years 2012 to 2023. Sixty-three studies were identified for review. Intracranial oscillations, cerebral perfusion, and arterial pulsations have been identified as major drivers of glymphatic influx. Each of these processes are diminished following craniectomy, suggesting craniectomy may impair glymphatic function. Reductions in brain pulsatility and alterations in glymphatic drainage after craniectomy were accompanied by impaired functional outcomes, as seen in SoT. Radiologically, CSF flow alterations are seen after craniectomies, which improve with cranioplasty. Glymphatic system dysfunction after craniectomy and in SoT may be a potential therapeutic target for patients with iatrogenically altered cranial vault anatomy.
脑 glymphatic 系统是最近才被发现的中枢神经系统脑脊液(CSF)和废物运输系统,与多种神经系统疾病有关。颅骨减压切除术后会出现 CSF 动态变化,这表明该手术可能会影响脑泡功能。我们的目的是系统回顾现有文献,以了解脑 glymphatic 系统对颅骨减压切除术和 Trephined 综合征(SoT)患者的影响。我们在 PubMed 和 Embase 中检索了 2012 年至 2023 年间有关甘液系统与颅骨切除术、开颅术或 SoT 的临床前和临床研究。最终确定了 63 项研究供审查。颅内振荡、脑灌注和动脉搏动已被确定为甘液流入的主要驱动因素。这些过程在颅骨切除术后都会减弱,这表明颅骨切除术可能会损害甘液功能。颅骨切除术后脑搏动性的降低和甘液引流的改变会导致功能受损,这在 SoT 中也有所体现。从放射学角度看,颅骨切除术后会出现脑脊液流改变,而颅骨成形术后情况会有所改善。颅骨切除术后和SoT中的淋巴系统功能障碍可能是先天性颅顶解剖结构改变患者的潜在治疗目标。
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