Jörg Renkawitz is an endowed Peter Hans Hofschneider Professor in Molecular Medicine at Ludwig Maximilians-University Munich, Germany. Following his bachelor and Master's degrees in biochemistry, during which he was first introduced to the field of cell motility, he completed his doctoral work with Prof. Dr Stefan Jentsch at the Max Planck Institute of Biochemistry in Martinsried, Germany, studying the mechanisms of DNA repair. Still intrigued by the mechanics of migrating cells, he moved to the Institute of Science and Technology in Vienna, Austria for his postdoc with Prof. Dr Michael Sixt, which cemented his passion for understanding how motile cells navigate their environments. In 2018, he started his own lab at Ludwig Maximilians-University Munich, and now applies his molecular expertise to unravel the mechanobiology of the immune system by combining omics approaches with engineered microenvironments and high-throughput imaging. We spoke with Jörg over Zoom to learn about his career path, rigorous approaches to experimental design and mentorship philosophy.
约尔格-伦卡维茨是德国慕尼黑路德维希-马克西米利安大学分子医学彼得-汉斯-霍夫施奈德教授。在获得生物化学学士和硕士学位期间，他首次接触到细胞运动领域，之后在德国马丁斯里德马克斯-普朗克生物化学研究所师从斯特凡-詹茨教授完成了博士学业，研究 DNA 修复机制。他仍然对迁移细胞的力学原理很感兴趣，于是来到奥地利维也纳科技研究所，跟随迈克尔-西斯特（Michael Sixt）博士教授做博士后研究，这坚定了他对了解运动细胞如何在环境中导航的热情。2018年，他在慕尼黑路德维希-马克西米利安大学（Ludwig Maximilians-University Munich）成立了自己的实验室，现在他将自己的分子专业知识应用于通过将全局学方法与工程微环境和高通量成像相结合来揭示免疫系统的机械生物学。我们通过中联重科采访了约尔格，了解他的职业道路、严谨的实验设计方法和导师理念。
{"title":"Cell scientist to watch – Jörg Renkawitz","authors":"","doi":"10.1242/jcs.261954","DOIUrl":"https://doi.org/10.1242/jcs.261954","url":null,"abstract":"\u0000 Jörg Renkawitz is an endowed Peter Hans Hofschneider Professor in Molecular Medicine at Ludwig Maximilians-University Munich, Germany. Following his bachelor and Master's degrees in biochemistry, during which he was first introduced to the field of cell motility, he completed his doctoral work with Prof. Dr Stefan Jentsch at the Max Planck Institute of Biochemistry in Martinsried, Germany, studying the mechanisms of DNA repair. Still intrigued by the mechanics of migrating cells, he moved to the Institute of Science and Technology in Vienna, Austria for his postdoc with Prof. Dr Michael Sixt, which cemented his passion for understanding how motile cells navigate their environments. In 2018, he started his own lab at Ludwig Maximilians-University Munich, and now applies his molecular expertise to unravel the mechanobiology of the immune system by combining omics approaches with engineered microenvironments and high-throughput imaging. We spoke with Jörg over Zoom to learn about his career path, rigorous approaches to experimental design and mentorship philosophy.","PeriodicalId":510778,"journal":{"name":"Journal of Cell Science","volume":"37 36","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139775933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dan Dickinson is an Assistant Professor in Molecular Biosciences at the University of Texas at Austin (UT Austin), USA. He completed his doctoral studies at Stanford University in California, co-mentored by Prof. Bill Weis and Prof. James Nelson, where he became fascinated with cell polarity in the amoeba Dictyostelium discoideum. He next moved to Prof. Bob Goldstein's lab at the University of North Carolina at Chapel Hill for his postdoctoral research, where he developed a single-cell method to probe protein interactions in Caenorhabditis elegans zygotes. In 2017, he started his own lab at UT Austin. Intrigued by capacity of proteins to generate complex patterns across scales, his group aims to close the gap between biochemistry and cell biology using single-cell methods to investigate cell polarity in diverse contexts. For our Special Issue on Cell and Tissue Polarity, we spoke with Dan over Zoom about his goals as a researcher and educator and his dedication to teaching students the joy of scientific inquiry.
丹-迪金森是美国得克萨斯大学奥斯汀分校分子生物科学助理教授。他在加州斯坦福大学完成了博士学业，由 Bill Weis 教授和 James Nelson 教授共同指导，在那里他对盘状变形虫的细胞极性产生了浓厚的兴趣。随后，他来到北卡罗来纳大学教堂山分校鲍勃-戈尔茨坦教授的实验室从事博士后研究，在那里他开发了一种单细胞方法，用于探测秀丽隐杆线虫子囊中的蛋白质相互作用。2017 年，他在UT Austin 成立了自己的实验室。他的研究小组对蛋白质产生跨尺度复杂模式的能力很感兴趣，旨在缩小生物化学与细胞生物学之间的差距，利用单细胞方法研究各种情况下的细胞极性。在《细胞与组织极性特刊》中，我们与 Dan 通过 Zoom 谈论了他作为研究人员和教育工作者的目标，以及他教导学生科学探究乐趣的奉献精神。
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First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Tanja Müller is first author on ‘ The neuronal transcription factor MEIS2 is a calpain-2 protease target’, published in JCS. Tanja conducted the research described in this article while a PhD student in Prof. Dr Dorothea Schulte's lab at the Institute of Neurology (Edinger Institute), University Hospital Frankfurt, Germany. She is now a postdoc and co-lead of the Translational Neurooncology Junior Group in the lab of Dr Ann-Christin Hau at the Translational Neurooncology Group at the University Hospital Frankfurt, Germany. Her current research focuses on the identification of invasion-promoting genes in high-grade glial tumors.
First Person 是对《细胞科学杂志》上发表的部分论文的第一作者的系列采访，帮助研究人员在发表论文的同时宣传自己。Tanja Müller是发表在《细胞科学杂志》上的 "The neuronal transcription factor MEIS2 is a calpain-2 protease target "一文的第一作者。Tanja 在德国法兰克福大学医院神经病学研究所（艾丁格研究所）Dorothea Schulte 教授的实验室攻读博士学位期间，开展了本文所述的研究。她现在是德国法兰克福大学医院转化神经肿瘤学小组 Ann-Christin Hau 博士实验室的博士后和转化神经肿瘤学初级小组的共同负责人。她目前的研究重点是鉴定高级别胶质瘤中的侵袭促进基因。
{"title":"First person – Tanja Müller","authors":"","doi":"10.1242/jcs.262013","DOIUrl":"https://doi.org/10.1242/jcs.262013","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Tanja Müller is first author on ‘ The neuronal transcription factor MEIS2 is a calpain-2 protease target’, published in JCS. Tanja conducted the research described in this article while a PhD student in Prof. Dr Dorothea Schulte's lab at the Institute of Neurology (Edinger Institute), University Hospital Frankfurt, Germany. She is now a postdoc and co-lead of the Translational Neurooncology Junior Group in the lab of Dr Ann-Christin Hau at the Translational Neurooncology Group at the University Hospital Frankfurt, Germany. Her current research focuses on the identification of invasion-promoting genes in high-grade glial tumors.","PeriodicalId":510778,"journal":{"name":"Journal of Cell Science","volume":"542 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140455506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Calin Dragoi is first author on ‘ The oscillation of mitotic kinase governs cell cycle latches in mammalian cells’, published in JCS. Calin is a DPhil student in Biochemistry in the lab of Prof. Bela Novak at University of Oxford, Oxford, UK, using mathematical modelling to investigate the emergence of cell cycle properties.
First Person 是对《细胞科学杂志》上发表的部分论文的第一作者的系列采访，帮助研究人员在发表论文的同时宣传自己。Calin Dragoi 是发表在《细胞科学杂志》上的 "The oscillation of mitotic kinase governs cell cycle latches in mammalian cells "一文的第一作者。Calin 是英国牛津大学贝拉-诺瓦克（Bela Novak）教授实验室的生物化学博士生，利用数学建模研究细胞周期特性的出现。
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First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. JingHui Cao is first author on ‘ Artificial tethering of constitutive centromere-associated network proteins induces CENP-A deposition without Knl2 in DT40 cells’, published in JCS. JingHui is a PhD student in the lab of Tatsuo Fukagawa at the Graduate School of Frontier Biosciences, Osaka, Japan, investigating the relationship between cancer and chromosomal instability (CIN).
First Person 是对《细胞科学杂志》（Journal of Cell Science）上发表的部分论文的第一作者的系列采访，帮助研究人员在发表论文的同时宣传自己。曹景辉是《细胞科学杂志》（JCS）上发表的 "Artificial tethering of constitutive centromere-associated network proteins induces CENP-A deposition without Knl2 in DT40 cells "一文的第一作者。JingHui 是日本大阪前沿生物科学研究生院深川达夫实验室的博士生，研究癌症与染色体不稳定性（CIN）之间的关系。
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First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Ashley Peterson is first author on ‘ Neutrophil motility is regulated by both cell intrinsic and endothelial cell ARPC1B’, published in JCS. Ashley conducted the research described in this article while a graduate research assistant (PhD student) in Anna Huttenlocher's lab at the University of Wisconsin-Madison, USA. She is currently searching for jobs in pharmaceutical/biotech industry. Her research interests are in using in vitro and microfluidics systems to model human disease for drug discovery and preclinical testing.
First Person 是对《细胞科学杂志》上发表的部分论文的第一作者进行的系列采访，帮助研究人员在发表论文的同时宣传自己。Ashley Peterson 是发表在《细胞科学杂志》上的 "中性粒细胞的运动受细胞内在和内皮细胞 ARPC1B 的调控 "一文的第一作者。Ashley 在美国威斯康星大学麦迪逊分校 Anna Huttenlocher 实验室担任研究生助理（博士生）期间进行了本文所述的研究。她目前正在寻找制药/生物技术行业的工作。她的研究兴趣是利用体外和微流控系统为药物发现和临床前测试建立人类疾病模型。
{"title":"First person – Ashley Peterson","authors":"","doi":"10.1242/jcs.261983","DOIUrl":"https://doi.org/10.1242/jcs.261983","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Ashley Peterson is first author on ‘ Neutrophil motility is regulated by both cell intrinsic and endothelial cell ARPC1B’, published in JCS. Ashley conducted the research described in this article while a graduate research assistant (PhD student) in Anna Huttenlocher's lab at the University of Wisconsin-Madison, USA. She is currently searching for jobs in pharmaceutical/biotech industry. Her research interests are in using in vitro and microfluidics systems to model human disease for drug discovery and preclinical testing.","PeriodicalId":510778,"journal":{"name":"Journal of Cell Science","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139878337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Samuele Metti is co-first author on ‘ Native collagen VI delays early muscle stem cell differentiation’, published in JCS. Samuele conducted the research described in this article while a PhD student in Prof. Paolo Bonaldo's lab at University of Padova, Italy. He is now a postdoc in the lab of Prof. Gisou van der Goot at School of Life Science, École Polytechnique Fédérale de Lausanne, Switzerland, investigating how extracellular matrix proteins affect muscle stem cell behaviour.
First Person 是对《细胞科学杂志》上发表的部分论文的第一作者的系列采访，帮助研究人员在发表论文的同时宣传自己。Samuele Metti 是《细胞科学杂志》上发表的 "Native collagen VI delays early muscle stem cell differentiation "一文的共同第一作者。Samuele 在意大利帕多瓦大学 Paolo Bonaldo 教授的实验室攻读博士学位期间，开展了本文所述的研究。他现在是瑞士洛桑联邦理工学院生命科学学院 Gisou van der Goot 教授实验室的博士后，研究细胞外基质蛋白如何影响肌肉干细胞的行为。
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First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. JingHui Cao is first author on ‘ Artificial tethering of constitutive centromere-associated network proteins induces CENP-A deposition without Knl2 in DT40 cells’, published in JCS. JingHui is a PhD student in the lab of Tatsuo Fukagawa at the Graduate School of Frontier Biosciences, Osaka, Japan, investigating the relationship between cancer and chromosomal instability (CIN).
First Person 是对《细胞科学杂志》（Journal of Cell Science）上发表的部分论文的第一作者的系列采访，帮助研究人员在发表论文的同时宣传自己。曹景辉是《细胞科学杂志》（JCS）上发表的 "Artificial tethering of constitutive centromere-associated network proteins induces CENP-A deposition without Knl2 in DT40 cells "一文的第一作者。JingHui 是日本大阪前沿生物科学研究生院深川达夫实验室的博士生，研究癌症与染色体不稳定性（CIN）之间的关系。
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Jakub Sedzinski is an Associate Professor at the University of Copenhagen and the Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Denmark. After his undergraduate and Master's degrees in biotechnology at the University of Wroclaw, Poland, he completed his PhD in Prof. Ewa Paluch's lab at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany, where he studied biophysical aspects of fundamental cell behaviours. Next, he moved to the University of Texas at Austin in the USA for a postdoctoral fellowship with Prof. John Wallingford. There, he became interested in how cell-level mechanics influence the complex development and maintenance of tissues like the mucociliary epithelium. In 2017, he started his own lab in Copenhagen where he continues to integrate biophysics with cell biology and developmental models in order to elucidate the relationships between cell and tissue mechanics and cell fate acquisition in epithelial tissue dynamics. We spoke with Jakub over Zoom about his career and how his cross-disciplinary approach to research is driven by his fundamental passion for learning new things.
Jakub Sedzinski 是丹麦哥本哈根大学和诺和诺德基金会干细胞医学中心 (reNEW) 的副教授。在波兰弗罗茨瓦夫大学获得生物技术本科和硕士学位后，他在德国德累斯顿马克斯-普朗克分子细胞生物学和遗传学研究所 Ewa Paluch 教授的实验室攻读博士学位，研究基本细胞行为的生物物理方面。随后，他前往美国德克萨斯大学奥斯汀分校，跟随约翰-沃林福德教授从事博士后研究。在那里，他对细胞级力学如何影响粘膜上皮等组织的复杂发育和维持产生了浓厚的兴趣。2017年，他在哥本哈根成立了自己的实验室，继续将生物物理学与细胞生物学和发育模型相结合，以阐明细胞和组织力学与上皮组织动力学中细胞命运获得之间的关系。我们通过 Zoom 与 Jakub 谈论了他的职业生涯，以及他的跨学科研究方法是如何被他学习新事物的基本热情所驱动的。
{"title":"Cell scientist to watch – Jakub Sedzinski","authors":"","doi":"10.1242/jcs.261929","DOIUrl":"https://doi.org/10.1242/jcs.261929","url":null,"abstract":"\u0000 Jakub Sedzinski is an Associate Professor at the University of Copenhagen and the Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Denmark. After his undergraduate and Master's degrees in biotechnology at the University of Wroclaw, Poland, he completed his PhD in Prof. Ewa Paluch's lab at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany, where he studied biophysical aspects of fundamental cell behaviours. Next, he moved to the University of Texas at Austin in the USA for a postdoctoral fellowship with Prof. John Wallingford. There, he became interested in how cell-level mechanics influence the complex development and maintenance of tissues like the mucociliary epithelium. In 2017, he started his own lab in Copenhagen where he continues to integrate biophysics with cell biology and developmental models in order to elucidate the relationships between cell and tissue mechanics and cell fate acquisition in epithelial tissue dynamics. We spoke with Jakub over Zoom about his career and how his cross-disciplinary approach to research is driven by his fundamental passion for learning new things.","PeriodicalId":510778,"journal":{"name":"Journal of Cell Science","volume":"5 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139875965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Calin Dragoi is first author on ‘ The oscillation of mitotic kinase governs cell cycle latches in mammalian cells’, published in JCS. Calin is a DPhil student in Biochemistry in the lab of Prof. Bela Novak at University of Oxford, Oxford, UK, using mathematical modelling to investigate the emergence of cell cycle properties.
First Person 是对《细胞科学杂志》上发表的部分论文的第一作者的系列采访，帮助研究人员在发表论文的同时宣传自己。Calin Dragoi 是发表在《细胞科学杂志》上的 "The oscillation of mitotic kinase governs cell cycle latches in mammalian cells "一文的第一作者。Calin 是英国牛津大学贝拉-诺瓦克（Bela Novak）教授实验室的生物化学博士生，利用数学建模研究细胞周期特性的出现。
{"title":"First person – Calin Dragoi","authors":"","doi":"10.1242/jcs.261974","DOIUrl":"https://doi.org/10.1242/jcs.261974","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers promote themselves alongside their papers. Calin Dragoi is first author on ‘ The oscillation of mitotic kinase governs cell cycle latches in mammalian cells’, published in JCS. Calin is a DPhil student in Biochemistry in the lab of Prof. Bela Novak at University of Oxford, Oxford, UK, using mathematical modelling to investigate the emergence of cell cycle properties.","PeriodicalId":510778,"journal":{"name":"Journal of Cell Science","volume":"35 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139819731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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