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Reply to Letter Regarding “A Randomized, Double-Blind, Placebo-Controlled Trial on the Efficacy of Dexamethasone Combined With Neuraxial Anesthesia in Reducing Pain and Opioid Consumption After Primary Cementless Total Hip Arthroplasty Using the Direct Anterior Approach” 关于“一项随机、双盲、安慰剂对照试验:地塞米松联合轴向麻醉减少直接前路一期无骨水泥全髋关节置换术后疼痛和阿片类药物消耗的疗效”的回复
IF 3.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-26 DOI: 10.1016/j.arth.2025.07.055
Wouter Schroven MD, Dries Verrewaere MD, Thomas Deckmyn MD, Maxence Vandekerckhove MD, Anthony Van Eemeren MD, Jan Vanlommel MD
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引用次数: 0
The Challenges With Artificial Intelligence in Scientific Writing 人工智能在科学写作中的挑战
IF 3.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-26 DOI: 10.1016/j.arth.2025.12.001
Giles R. Scuderi MD, Michael J. Taunton MD, James A. Browne MD, Michael A. Mont MD
Artificial intelligence (AI) is rapidly reshaping scientific writing, peer review, and academic publishing. While these technologies offer benefits, including improved clarity, enhanced editorial screening, and expanded global accessibility, they also present substantial challenges. Among the most pressing concerns are accuracy, bias, intellectual property, security, and the potential manipulation of peer review systems. Publishers and editorial boards continue to refine policies to maintain scientific rigor, ensure transparency in AI use, and protect the integrity of human authorship. This article reviews the legal, ethical, and practical challenges associated with AI in medical publishing, highlights emerging risks such as hidden prompts and data security vulnerabilities, and explores how journals, like the Journal of Arthroplasty, can balance innovation with responsible oversight.
人工智能(AI)正在迅速重塑科学写作、同行评审和学术出版。虽然这些技术带来了好处,包括提高清晰度、加强编辑筛选和扩大全球可及性,但它们也带来了重大挑战。其中最紧迫的问题是准确性、偏见、知识产权、安全性以及对同行评审系统的潜在操纵。出版商和编辑委员会继续完善政策,以保持科学严谨性,确保人工智能使用的透明度,并保护人类作者的完整性。本文回顾了医学出版中与人工智能相关的法律、伦理和实践挑战,强调了诸如隐藏提示和数据安全漏洞等新出现的风险,并探讨了《关节成形术杂志》等期刊如何在创新与负责任的监督之间取得平衡。
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引用次数: 0
Comment on “A Randomized, Double-Blind, Placebo-Controlled Trial on the Efficacy of Dexamethasone Combined With Neuraxial Anesthesia in Reducing Pain and Opioid Consumption After Primary Cementless Total Hip Arthroplasty Using the Direct Anterior Approach” “一项随机、双盲、安慰剂对照试验:地塞米松联合轴向麻醉在直接前路首次无骨水泥全髋关节置换术后减轻疼痛和阿片类药物消耗的疗效”评论
IF 3.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-26 DOI: 10.1016/j.arth.2025.07.051
Jiekun Jian MMed, Xianwen Sun MMed
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引用次数: 0
Outcomes After Conversion of High Tibial Osteotomy to Total Knee Arthroplasty: Nearly 14-Year Follow-Up in a United States Population. 美国人群胫骨高位截骨转全膝关节置换术后的长期疗效分析。
IF 3.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-19 DOI: 10.1016/j.arth.2025.12.034
Eva A Bax, Rana A Ahmad, Marieke A Kietselaer, Sean C Clark, Roel J H Custers, Michael J Taunton, Rafael J Sierra, Mario Hevesi, Daniel B F Saris

Background: High tibial osteotomy (HTO) is a joint-preserving treatment for younger patients who have unicompartmental knee osteoarthritis. Although effective, concerns persist that prior HTO may compromise subsequent total knee arthroplasty (TKA). This study aimed to assess the revision-free survival of TKA following ipsilateral HTO and identify factors associated with failure of both procedures in a U.S.

Population:

Methods: Patients who underwent TKA after prior ipsilateral HTO between 2000 and 2023 at a single academic institution were prospectively followed (n = 134), with a mean follow-up of 13.5 years (range, zero to 24.0) postoperative TKA and median ages at HTO and TKA of 52 and 63 years, respectively. Preoperative TKA radiographs were assessed using the Kellgren and Lawrence system. Kaplan-Meier analysis was performed to assess HTO and TKA survival. The mean HTO survival was 11.7 years (range, zero to 31.0), with a 10-year TKA conversion rate of 35.8%. Cox regressions identified factors associated with osteotomy survival.

Results: Older age (hazard ratio [HR]: 1.06; P < 0.001), higher body mass index (HR: 1.03; P = 0.033), and lower Charlson Comorbidity Index (CCI) (HR: 0.79; P < 0.001) were significantly associated with earlier conversion. Following TKA, 6.0% underwent revision surgery. Revisions were more common in younger patients (P = 0.01) and those who had lower CCI (P = 0.002). The infection rate for postoperative TKA was 2.2%.

Conclusions: In this U.S. cohort, TKA following prior ipsilateral HTO demonstrated a revision rate of 6.0%, with younger patients who have lower CCI scores more likely to require revision. The mean survival of HTO was approximately 12 years, with age, body mass index, and comorbidity index significantly influencing longevity. These findings support HTO as a durable joint-preserving treatment in younger patients, helping to guide clinical decision-making and may contribute to increased consideration of HTO as a treatment option in suitable people.

背景:胫骨高位截骨术(HTO)是一种保护关节的治疗方法,适用于年轻的单室膝骨关节炎患者。虽然有效,但先前的HTO可能会影响后续的全膝关节置换术(TKA)。本研究旨在评估美国人群中同侧HTO术后TKA的无修复生存,并确定两种手术失败的相关因素。方法:前瞻性随访2000年至2023年间在单一学术机构接受同侧HTO后接受TKA的患者(n = 134),平均随访时间为13.5年(范围为0.0至24.0),HTO和TKA的中位年龄分别为52岁和63岁。术前TKA x线片采用Kellgren和Lawrence系统进行评估。采用Kaplan-Meier分析评估HTO和TKA的生存率。平均HTO生存期为11.7年(范围为0.0 ~ 31.0年),10年TKA转换率为35.8%。Cox回归确定了与截骨术存活率相关的因素。结果:年龄越大(危险比1.06,P < 0.001)、体重指数(BMI)越高(危险比1.03,P = 0.033)、Charlson合病指数(CCI)越低(危险比0.79,P < 0.001)与早期转化有显著相关性。TKA后,6.0%的患者接受了翻修手术。修订在年轻患者(P = 0.01)和CCI较低患者(P = 0.002)中更为常见。术后TKA感染率为2.2%。结论:在这个美国队列中,先前同侧HTO后的TKA翻修率为6.0%,CCI评分较低的年轻患者更有可能需要翻修。HTO的平均生存期约为12年,年龄、BMI和合并症指数显著影响寿命。这些发现支持HTO作为年轻患者持久的关节保持治疗,有助于指导临床决策,并可能有助于增加HTO作为治疗选择的考虑。
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引用次数: 0
The Shift to Outpatient Total Hip and Knee Arthroplasty: Perioperative Work Has Not Changed. 转向门诊全髋关节和膝关节置换术:围手术期工作没有改变。
IF 3.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-18 DOI: 10.1016/j.arth.2025.12.035
Hunter Warwick, Neeku Salehi, David N Kugelman, Ramakanth Yakkanti, Chad A Krueger, P Maxwell Courtney

Background: Total hip arthroplasty (THA) and knee arthroplasty (TKA) are increasingly being performed on an outpatient basis. With this shift in site of service, the volume and complexity of work required for these procedures may be affected. The purpose of this study was to quantify the amount of perioperative work performed by the surgeon and advanced practice providers for same-day THA and TKA.

Methods: We prospectively timed preservice, immediate postservice, and discharge coordination activities for a consecutive series of 96 outpatient cases over a 4-week period. Timing data for activities performed in the operating room were obtained retrospectively from our institutional electronic medical record for 500 patients who underwent THA and 500 who underwent TKA. Results were compared with the current approved values reviewed by the Relative Value Scale Update Committee (RUC) in 2019. Cases were also separated into those performed in tertiary care hospitals, specialty hospitals, and ambulatory surgical centers to compare perioperative work by surgical setting.

Results: The average pre-evaluation time was 43.9 ± 7.3 minutes. The average time from the patient entering the operating room to incision was 39.0 ± 9.8 minutes. Immediate post-service tasks took 26.6 ± 7.2 minutes, and discharge coordination tasks took 122.1 ± 33.9 minutes. Overall, tasks measured took 231.6 minutes and were allotted only 208 minutes by the 2019 RUC. All phases of perioperative work took longer at ambulatory surgical centers relative to other settings, particularly discharge coordination, which took an average of 140.3 minutes (P = 0.043).

Conclusion: Outpatient arthroplasty requires at least the same amount of perioperative work as traditional inpatient arthroplasty. Further, our results suggest surgical teams are doing more work than is currently valued by the RUC. Policymakers should take this information into consideration while evaluating TKA and THA as these procedures continue to move to the outpatient setting.

背景:全髋关节(THA)和膝关节置换术(TKA)越来越多地在门诊进行。由于服务地点的这种转移,这些程序所需工作的数量和复杂性可能会受到影响。本研究的目的是量化外科医生和高级实践提供者进行当日THA和TKA的围手术期工作量。方法:我们在4周的时间内对96例连续的门诊病例进行了预期的服务前、立即服务后和出院协调活动。回顾性地从500例THA患者和500例TKA患者的机构电子病历中获得了在手术室(OR)进行活动的时间数据。结果与2019年相对价值比额表更新委员会(RUC)审查的当前批准值进行了比较。病例也被分为三级医院、专科医院和门诊外科中心(ASCs),以比较不同手术环境的围手术期工作。结果:平均预评时间为43.9±7.3 min。患者入手术室至切口平均时间为39.0±9.8分钟。立即离职任务耗时26.6±7.2分钟,出院协调任务耗时122.1±33.9分钟。总体而言,测量的任务耗时231.6分钟,而2019年的人大只分配了208分钟。与其他设置相比,ASCs围手术期的所有阶段工作都需要更长时间,特别是出院协调,平均需要140.3分钟(P = 0.043)。结论:门诊THA和TKA至少需要与传统住院关节置换术相同的围手术期工作量。此外,我们的结果表明,外科团队所做的工作比RUC目前所重视的要多。决策者在评估TKA和THA时应考虑到这些信息,因为这些程序继续向门诊环境转移。
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引用次数: 0
General, Spinal, and Regional Nerve Blocks: Do Different Anesthesia Practices Affect Same-Day Discharge in Primary Total Hip and Knee Arthroplasty? 全身、脊柱和局部神经阻滞:不同的麻醉方式对初次全髋关节置换术患者当日出院有影响吗?
IF 3.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-18 DOI: 10.1016/j.arth.2025.12.033
Clayton W Wing, Behnaz Hatami, Ahmad T Oseili, Daniel S Ubl, Bryan D Springer, Alberto E Ardon, Cameron K Ledford

Background: The purpose of this study was to compare the effect of spinal anesthesia (SA) versus general anesthesia (GA) on acute 90-day outcomes in same-day discharge (SDD) total hip (THA) and total knee arthroplasty (TKA) patients, including subgroup analysis of peripheral nerve block usage.

Methods: A retrospective review of 1,002 SDD patients (402 THAs, 600 TKAs) was performed, including 868 and 134 undergoing SA and GA, respectively. All patients received periarticular injections and multimodal analgesia; 80% of THAs received a paravertebral block (PVB), and 58% of TKAs received an adductor canal block (ACB). Intraoperative and postoperative narcotic usage (morphine milligram equivalents, MMEs) through SDD, numerical pain scores, first ambulation distance, hospital length of stay, and 90-day complications (readmissions or reoperations) were compared.

Results: The SA performed in SDD THA resulted in decreased intraoperative MME (0.1 versus 8.7, P < 0.01), postoperative MME (12.3 versus 16.1, P < 0.02), and pain scores (1.6 versus 3.8, P < 0.01). A similar result was found in TKA, as SA patients had decreased intraoperative MME (0.1 versus 13.1, respectively, P < 0.01), postoperative MME (9.7 versus 15.5, P < 0.01), and pain scores (1.5 versus 3.2, P < 0.01). There was no difference in hospital length of stay between groups, but THA patients undergoing GA showed an increased 90-day readmission rate (4.8 versus 0.3%, P < 0.01). For SA, the use of PVBs in THA reduced postoperative MMEs and pain scores, while there were minimal effects with ACBs in TKA.

Conclusions: For SDD THA and TKA patients, SA improved intraoperative and immediate postoperative pain control compared to GA without affecting acute recovery. The use of PVBs modestly improved acute pain for THA, while ACBs for TKA did not demonstrate the same effect in the setting of contemporary multimodal analgesia.

Level of evidence: Level 4, retrospective review.

背景:本研究的目的是比较脊髓麻醉(SA)与全身麻醉(GA)对当日出院(SDD)全髋关节(THA)和全膝关节置换术(TKA)患者90天急性预后的影响,包括周围神经阻滞使用的亚组分析。方法:回顾性分析1002例SDD患者(402例tha, 600例tka),其中868例行SA, 134例行GA。所有患者均接受关节周注射和多模式镇痛;80%的tha患者接受椎旁阻滞(PVB), 58%的tka患者接受内收管阻滞(ACB)。通过SDD比较术中和术后麻醉用量(吗啡毫克当量,MME)、数值疼痛评分、首次行走距离、住院时间(LOS)和90天并发症(再入院或再手术)。结果:SDD THA行SA可降低术中MME(0.1比8.7,P < 0.01)、术后MME(12.3比16.1,P < 0.02)和疼痛评分(1.6比3.8,P < 0.01)。在TKA中发现了类似的结果,SA患者术中MME(分别为0.1比13.1,P < 0.01),术后MME(9.7比15.5,P < 0.01)和疼痛评分(1.5比3.2,P < 0.01)均降低。两组间LOS无差异,但行GA的THA患者90天再入院率增加(4.8 vs 0.3%, P < 0.01)。对于SA,在THA中使用PVBs降低了术后MMEs和疼痛评分,而在TKA中使用ACBs的影响很小。结论:对于SDD THA和TKA患者,与GA相比,SA改善了术中和术后即时疼痛控制,且不影响急性恢复。PVBs的使用适度改善了全髋关节置换术的急性疼痛,而ACBs在全髋关节置换术中并没有显示出相同的效果。
{"title":"General, Spinal, and Regional Nerve Blocks: Do Different Anesthesia Practices Affect Same-Day Discharge in Primary Total Hip and Knee Arthroplasty?","authors":"Clayton W Wing, Behnaz Hatami, Ahmad T Oseili, Daniel S Ubl, Bryan D Springer, Alberto E Ardon, Cameron K Ledford","doi":"10.1016/j.arth.2025.12.033","DOIUrl":"10.1016/j.arth.2025.12.033","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this study was to compare the effect of spinal anesthesia (SA) versus general anesthesia (GA) on acute 90-day outcomes in same-day discharge (SDD) total hip (THA) and total knee arthroplasty (TKA) patients, including subgroup analysis of peripheral nerve block usage.</p><p><strong>Methods: </strong>A retrospective review of 1,002 SDD patients (402 THAs, 600 TKAs) was performed, including 868 and 134 undergoing SA and GA, respectively. All patients received periarticular injections and multimodal analgesia; 80% of THAs received a paravertebral block (PVB), and 58% of TKAs received an adductor canal block (ACB). Intraoperative and postoperative narcotic usage (morphine milligram equivalents, MMEs) through SDD, numerical pain scores, first ambulation distance, hospital length of stay, and 90-day complications (readmissions or reoperations) were compared.</p><p><strong>Results: </strong>The SA performed in SDD THA resulted in decreased intraoperative MME (0.1 versus 8.7, P < 0.01), postoperative MME (12.3 versus 16.1, P < 0.02), and pain scores (1.6 versus 3.8, P < 0.01). A similar result was found in TKA, as SA patients had decreased intraoperative MME (0.1 versus 13.1, respectively, P < 0.01), postoperative MME (9.7 versus 15.5, P < 0.01), and pain scores (1.5 versus 3.2, P < 0.01). There was no difference in hospital length of stay between groups, but THA patients undergoing GA showed an increased 90-day readmission rate (4.8 versus 0.3%, P < 0.01). For SA, the use of PVBs in THA reduced postoperative MMEs and pain scores, while there were minimal effects with ACBs in TKA.</p><p><strong>Conclusions: </strong>For SDD THA and TKA patients, SA improved intraoperative and immediate postoperative pain control compared to GA without affecting acute recovery. The use of PVBs modestly improved acute pain for THA, while ACBs for TKA did not demonstrate the same effect in the setting of contemporary multimodal analgesia.</p><p><strong>Level of evidence: </strong>Level 4, retrospective review.</p>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uncontrolled Diabetes Mellitus in the Year Prior to Total Hip or Knee Arthroplasty Is Associated with Similar Perioperative Glucose Control, Early Complication Rates, and 5-Year Reoperation Rates after Preoperative Diabetes Mellitus Optimization. 全髋关节或膝关节置换术前一年未控制的糖尿病与围手术期血糖控制、早期并发症发生率和术前糖尿病优化后5年再手术率相关。
IF 3.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-18 DOI: 10.1016/j.arth.2025.12.029
Jonathan Umelo, Ayodeji Jubril, Philomena U Burger, Janet N Tran, Rishi Balkissoon, Nathan B Kaplan, Caroline P Thirukumaran, Benjamin F Ricciardi

Background: Perioperative glycemic control is considered a modifiable risk factor prior to primary total hip and total knee arthroplasty; however, it is still unknown whether preoperatively optimizing hemoglobin A1C values affects perioperative glucose control or postoperative complications. The purpose of this study was to compare patients who required preoperative diabetes mellitus (DM) optimization in the year prior to surgery (defined as hemoglobin A1C ≥ 8%) versus patients who had DM who did not require preoperative DM optimization to compare (1) postoperative glycemic control and (2) 90-day complications and incidence of revision arthroplasty.

Methods: This was a retrospective single-center analysis. Patients undergoing primary total joint arthroplasty who had a diagnosis of DM (hemoglobin A1C greater than 6.5%) were eligible for inclusion (N = 585). Patients who had previously uncontrolled DM requiring optimization (hemoglobin A1C ≥ 8.0%) in the year prior to surgery (N = 164) were compared to patients who had controlled DM (N = 421). All patients had hemoglobin A1C less than 8% preoperatively. Outcomes included median and peak perioperative glycemic control (postoperative day zero to two), 90-day complications, and incidence of revision arthroplasty at the final follow-up (mean 64 months). Multivariable logistic regressions evaluated associations of underlying preoperative demographic and treatment characteristics with outcomes.

Results: Early postoperative median serum glucose and peak serum glucose were similar between patients who had controlled versus optimized DM. Higher preoperative hemoglobin A1C and peak hemoglobin A1C in the year prior to surgery were associated with worse median and peak serum glucose. The 90-day complication rates were similar in patients needing DM optimization versus controlled DM patients (odds ratio 1.67, 95% confidence interval 0.91 to 2.88; P = 0.10). Metformin use was independently associated with lower complication rates. Reoperations were similar between patients requiring preoperative DM optimization versus controlled DM (odds ratio 1.60, 95% confidence interval 0.59 to 4.36, P = 0.35).

Conclusions: This study suggests that the need for DM optimization does not affect perioperative glucose control, postoperative complications, or reoperations, suggesting that efforts to optimize hemoglobin A1C prior to total hip and total knee arthroplasty are warranted.

背景:围手术期血糖控制被认为是原发性全髋关节(THA)和全膝关节(TKA)置换术前可改变的危险因素;然而,术前优化血红蛋白A1C值是否影响围术期血糖控制或术后并发症尚不清楚。本研究的目的是比较术前一年需要术前糖尿病(DM)优化的患者(定义为血红蛋白A1C≥8%)与不需要术前DM优化的DM患者,比较1)术后血糖控制和2)90天并发症和翻修性关节置换术的发生率。方法:回顾性单中心分析。接受原发性全关节置换术(TJA)且诊断为DM(血红蛋白A1C bb0 6.5%)的患者符合纳入条件(N = 585)。术前一年需要优化治疗的未控制糖尿病患者(血红蛋白A1C≥8.0%)(N = 164)与控制糖尿病患者(N = 421)进行比较。所有患者术前血红蛋白A1C均< 8%。结果包括围手术期血糖控制的中位和峰值(术后一天[POD] 0至2),90天的并发症,以及最终随访时翻修关节置换术的发生率(平均64个月)。多变量logistic回归评估了术前基本人口学特征和治疗特征与预后的关系。结果:控制型糖尿病患者与优化型糖尿病患者术后早期的中位血糖和峰值血糖相似。术前糖化血红蛋白和术前一年糖化血红蛋白峰值较高与较差的中位血糖和峰值血糖相关。需要优化糖尿病的患者与对照糖尿病患者的90天并发症发生率相似(OR[优势比]1.67,95% CI[置信区间]0.91至2.88;P = 0.10)。二甲双胍的使用与较低的并发症发生率独立相关。术前DM优化患者与对照DM患者的再手术率相似(OR 1.60, 95% CI 0.59 ~ 4.36, P = 0.35)。结论:本研究提示糖尿病优化并不影响围手术期血糖控制、术后并发症或再手术,提示在THA和TKA前优化血红蛋白A1C是有必要的。
{"title":"Uncontrolled Diabetes Mellitus in the Year Prior to Total Hip or Knee Arthroplasty Is Associated with Similar Perioperative Glucose Control, Early Complication Rates, and 5-Year Reoperation Rates after Preoperative Diabetes Mellitus Optimization.","authors":"Jonathan Umelo, Ayodeji Jubril, Philomena U Burger, Janet N Tran, Rishi Balkissoon, Nathan B Kaplan, Caroline P Thirukumaran, Benjamin F Ricciardi","doi":"10.1016/j.arth.2025.12.029","DOIUrl":"10.1016/j.arth.2025.12.029","url":null,"abstract":"<p><strong>Background: </strong>Perioperative glycemic control is considered a modifiable risk factor prior to primary total hip and total knee arthroplasty; however, it is still unknown whether preoperatively optimizing hemoglobin A1C values affects perioperative glucose control or postoperative complications. The purpose of this study was to compare patients who required preoperative diabetes mellitus (DM) optimization in the year prior to surgery (defined as hemoglobin A1C ≥ 8%) versus patients who had DM who did not require preoperative DM optimization to compare (1) postoperative glycemic control and (2) 90-day complications and incidence of revision arthroplasty.</p><p><strong>Methods: </strong>This was a retrospective single-center analysis. Patients undergoing primary total joint arthroplasty who had a diagnosis of DM (hemoglobin A1C greater than 6.5%) were eligible for inclusion (N = 585). Patients who had previously uncontrolled DM requiring optimization (hemoglobin A1C ≥ 8.0%) in the year prior to surgery (N = 164) were compared to patients who had controlled DM (N = 421). All patients had hemoglobin A1C less than 8% preoperatively. Outcomes included median and peak perioperative glycemic control (postoperative day zero to two), 90-day complications, and incidence of revision arthroplasty at the final follow-up (mean 64 months). Multivariable logistic regressions evaluated associations of underlying preoperative demographic and treatment characteristics with outcomes.</p><p><strong>Results: </strong>Early postoperative median serum glucose and peak serum glucose were similar between patients who had controlled versus optimized DM. Higher preoperative hemoglobin A1C and peak hemoglobin A1C in the year prior to surgery were associated with worse median and peak serum glucose. The 90-day complication rates were similar in patients needing DM optimization versus controlled DM patients (odds ratio 1.67, 95% confidence interval 0.91 to 2.88; P = 0.10). Metformin use was independently associated with lower complication rates. Reoperations were similar between patients requiring preoperative DM optimization versus controlled DM (odds ratio 1.60, 95% confidence interval 0.59 to 4.36, P = 0.35).</p><p><strong>Conclusions: </strong>This study suggests that the need for DM optimization does not affect perioperative glucose control, postoperative complications, or reoperations, suggesting that efforts to optimize hemoglobin A1C prior to total hip and total knee arthroplasty are warranted.</p>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can External Rotator Preservation Reduce Dislocation Risk Following Posterior Approach Total Hip Arthroplasty in High-Risk Patients? A Propensity-Matched Comparative Study. 保留外旋肌能否降低高危患者后路全髋关节置换术后脱位的风险?倾向匹配比较研究。
IF 3.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-18 DOI: 10.1016/j.arth.2025.12.024
Seok-Hyung Won, Yongwon Joh, Young-Wook Lim, Soon-Yong Kwon, Yong-Sik Kim, Seung-Chan Kim

Background: Although multiple studies have examined the efficacy of muscle-sparing techniques in reducing dislocation after posterior approach THA, their findings are limited by small sample sizes and short follow-up durations, and to our knowledge, none have specifically evaluated outcomes in high-risk patients. This study compared the overall and 90-day dislocation risks of the previously described external rotator preservation (ERP) and standard posterior approach THA in high-risk patients.

Methods: We retrospectively reviewed patients who underwent THA between January 2008 and December 2022 at three tertiary centers, including those who had osteonecrosis of the femoral head (ONFH), inflammatory arthritis (IA), or a history of lumbar spinal fusion. Patients who underwent the ERP approach were identified from medical records and matched 1:1 to controls (standard posterior approach) by age, sex, body mass index, American Society of Anesthesiologists score, year of surgery, and surgical indication, yielding 501 patients per group. Binary logistic regressions were used to compare overall and 90-day dislocation risk. Kaplan-Meier analysis evaluated revision due to dislocation and all-cause revision. Surgical complications, Harris Hip Score (HHS), and postoperative radiographic parameters were compared. The mean follow-up was 10.7 years.

Results: The ERP group showed lower overall (odds ratio, 0.25; P < 0.001) and 90-day dislocation risks (odds ratio, 0.20; P = 0.002). Subgroup analyses revealed reduced dislocation risks in the ONFH and IA patients, with no difference in the lumbar spinal fusion subgroup. The estimated 10-year survivorship free from both revision for dislocation (P = 0.302) and any revision (P = 0.739) was similar. Other complications, the latest Harris Hip Score, and radiographic parameters were comparable.

Conclusions: The ERP approach for THA demonstrated lower overall and 90-day dislocation rates compared to the standard posterior approach in patients at high risk of dislocation without compromising long-term outcomes. The ERP may serve as an effective option for performing posterior approach THA in ONFH and IA patients.

Level of evidence: Level III, retrospective cohort study.

背景:虽然已有多项研究考察了保留肌肉技术在后路THA术后减少脱位的疗效,但其研究结果受到样本量小、随访时间短的限制,而且据我们所知,没有一项研究专门评估了高危患者的预后。本研究比较了先前描述的外旋肌保留(ERP)和标准后路THA在高危患者中的整体脱位风险和90天脱位风险。方法:我们回顾性分析了2008年1月至2022年12月在三个三级中心接受THA治疗的患者,包括股骨头骨坏死(ONFH)、炎症性关节炎(IA)或腰椎融合(LSF)史的患者。采用ERP入路的患者从医疗记录中确定,并按年龄、性别、体重指数、美国麻醉医师学会评分、手术年份和手术指征与对照组(标准后路入路)1:1匹配,每组501例患者。二元logistic回归用于比较总体和90天脱位风险。Kaplan-Meier分析评估脱位矫正和全因矫正。比较手术并发症、Harris髋关节评分(HHS)和术后影像学参数。平均随访10.7年。结果:ERP组整体较低(比值比[OR], 0.25; P < 0.001), 90天脱位风险较低(OR, 0.20; P = 0.002)。亚组分析显示,ONFH和IA患者脱位风险降低,LSF亚组无差异。无脱位翻修(P = 0.302)和任何翻修(P = 0.739)的估计10年生存率相似。其他并发症、最新HHS和影像学参数具有可比性。结论:在不影响长期预后的情况下,与标准后路入路相比,ERP入路治疗THA的总体脱位率和90天脱位率较低。保留外旋肌可作为ONFH和IA患者后路THA的有效选择。
{"title":"Can External Rotator Preservation Reduce Dislocation Risk Following Posterior Approach Total Hip Arthroplasty in High-Risk Patients? A Propensity-Matched Comparative Study.","authors":"Seok-Hyung Won, Yongwon Joh, Young-Wook Lim, Soon-Yong Kwon, Yong-Sik Kim, Seung-Chan Kim","doi":"10.1016/j.arth.2025.12.024","DOIUrl":"10.1016/j.arth.2025.12.024","url":null,"abstract":"<p><strong>Background: </strong>Although multiple studies have examined the efficacy of muscle-sparing techniques in reducing dislocation after posterior approach THA, their findings are limited by small sample sizes and short follow-up durations, and to our knowledge, none have specifically evaluated outcomes in high-risk patients. This study compared the overall and 90-day dislocation risks of the previously described external rotator preservation (ERP) and standard posterior approach THA in high-risk patients.</p><p><strong>Methods: </strong>We retrospectively reviewed patients who underwent THA between January 2008 and December 2022 at three tertiary centers, including those who had osteonecrosis of the femoral head (ONFH), inflammatory arthritis (IA), or a history of lumbar spinal fusion. Patients who underwent the ERP approach were identified from medical records and matched 1:1 to controls (standard posterior approach) by age, sex, body mass index, American Society of Anesthesiologists score, year of surgery, and surgical indication, yielding 501 patients per group. Binary logistic regressions were used to compare overall and 90-day dislocation risk. Kaplan-Meier analysis evaluated revision due to dislocation and all-cause revision. Surgical complications, Harris Hip Score (HHS), and postoperative radiographic parameters were compared. The mean follow-up was 10.7 years.</p><p><strong>Results: </strong>The ERP group showed lower overall (odds ratio, 0.25; P < 0.001) and 90-day dislocation risks (odds ratio, 0.20; P = 0.002). Subgroup analyses revealed reduced dislocation risks in the ONFH and IA patients, with no difference in the lumbar spinal fusion subgroup. The estimated 10-year survivorship free from both revision for dislocation (P = 0.302) and any revision (P = 0.739) was similar. Other complications, the latest Harris Hip Score, and radiographic parameters were comparable.</p><p><strong>Conclusions: </strong>The ERP approach for THA demonstrated lower overall and 90-day dislocation rates compared to the standard posterior approach in patients at high risk of dislocation without compromising long-term outcomes. The ERP may serve as an effective option for performing posterior approach THA in ONFH and IA patients.</p><p><strong>Level of evidence: </strong>Level III, retrospective cohort study.</p>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Total Hip Arthroplasty in Patients Who Have a Body Mass Index > 50: Is the Risk Worth the Reward? 原发性全髋关节置换术治疗体重指数为bb50的患者:风险值得回报吗?
IF 3.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-18 DOI: 10.1016/j.arth.2025.12.030
Christiaan H Righolt, Colby Finney, Thomas R Turgeon, Eric R Bohm, Jhase Sniderman

Background: The obesity epidemic has given rise to a growing number of patients who have a body mass index (BMI) exceeding 50. As BMI cutoffs are no longer recommended, arthroplasty surgeons continue to push the limits of surgical feasibility in total hip arthroplasty (THA) despite possible risks.

Methods: A retrospective cohort study of patients who underwent primary THA (N = 7,458) was developed, comparing outcomes between patients who had a BMI ≥ 50 (N = 147) and those of other weight classes. We used Cox proportional hazard models to estimate the association between patient BMI and revision risk using overweight patients (BMI 25 to 30) as the reference group. Patients entered the study cohort on their date of surgery and exited on the earliest of the date of revision, date of death, or the end of the study. Patient-reported outcome measures were compared pre- and postoperatively.

Results: Increased obesity class led to a gradient of elevated revision risk. In the first year after surgery, THA patients who had a BMI ≥ 50 demonstrated an adjusted hazard ratio (for revision of 11.8 (95% confidence interval [CI] 5.3 to 26.2). This risk was also elevated in patients who had a BMI of 40 to 50 (N = 635, hazard ratio = 3.8, 95% CI = 1.9 to 7.7). Although the patients who had a BMI ≥ 50 had a significantly worse preoperative Oxford-12 Hip score than other overweight patients, at five years, this difference was negligible.

Conclusions: There was an increased risk of early THA revision surgery in patients who had a BMI ≥ 50. This risk plateaued after the first year and was equivalent to other weight classes afterward. Despite worse preoperative function and greater failure rates, this population reports major benefits and high satisfaction with THA. The risk of THA appears to be worth it for most patients who have a BMI ≥ 50.

背景:肥胖的流行导致越来越多的患者身体质量指数(BMI)超过50。由于不再推荐BMI临界值,尽管可能存在风险,关节置换外科医生仍在继续推动全髋关节置换术(THA)手术可行性的极限。方法:对因退行性关节炎接受原发性THA治疗的患者(N = 7,458)进行回顾性队列研究,比较BMI≥50 (N = 147)和其他体重级别患者的结果。我们使用Cox比例风险模型,以超重患者(BMI为25 ~ 30)为参照组,估计患者BMI与翻修风险之间的关系。患者在手术日期进入研究队列,并在修订日期、死亡日期或研究结束日期中最早的日期退出。比较患者术前和术后的Oxford-12髋关节评分(OHS)。结果:肥胖等级增加导致翻修风险梯度升高。术后第一年,BMI≥50的THA患者的校正风险比(HR)为11.8(95%可信区间[CI] 5.3 - 26.2)。BMI在40 - 50之间的患者的这种风险也升高(N = 635,风险比(HR) = 3.8, 95% CI = 1.9 - 7.7)。虽然BMI≥50的患者术前OHS明显差于其他超重患者,但在5年后,这种差异可以忽略不计。结论:BMI≥50的患者早期THA翻修手术的风险增加。这种风险在第一年之后趋于稳定,之后与其他体重级别相当。尽管术前功能较差,失败率较高,但该人群报告THA的主要益处和高满意度。对于大多数BMI≥50的患者来说,THA的风险似乎是值得的。
{"title":"Primary Total Hip Arthroplasty in Patients Who Have a Body Mass Index > 50: Is the Risk Worth the Reward?","authors":"Christiaan H Righolt, Colby Finney, Thomas R Turgeon, Eric R Bohm, Jhase Sniderman","doi":"10.1016/j.arth.2025.12.030","DOIUrl":"10.1016/j.arth.2025.12.030","url":null,"abstract":"<p><strong>Background: </strong>The obesity epidemic has given rise to a growing number of patients who have a body mass index (BMI) exceeding 50. As BMI cutoffs are no longer recommended, arthroplasty surgeons continue to push the limits of surgical feasibility in total hip arthroplasty (THA) despite possible risks.</p><p><strong>Methods: </strong>A retrospective cohort study of patients who underwent primary THA (N = 7,458) was developed, comparing outcomes between patients who had a BMI ≥ 50 (N = 147) and those of other weight classes. We used Cox proportional hazard models to estimate the association between patient BMI and revision risk using overweight patients (BMI 25 to 30) as the reference group. Patients entered the study cohort on their date of surgery and exited on the earliest of the date of revision, date of death, or the end of the study. Patient-reported outcome measures were compared pre- and postoperatively.</p><p><strong>Results: </strong>Increased obesity class led to a gradient of elevated revision risk. In the first year after surgery, THA patients who had a BMI ≥ 50 demonstrated an adjusted hazard ratio (for revision of 11.8 (95% confidence interval [CI] 5.3 to 26.2). This risk was also elevated in patients who had a BMI of 40 to 50 (N = 635, hazard ratio = 3.8, 95% CI = 1.9 to 7.7). Although the patients who had a BMI ≥ 50 had a significantly worse preoperative Oxford-12 Hip score than other overweight patients, at five years, this difference was negligible.</p><p><strong>Conclusions: </strong>There was an increased risk of early THA revision surgery in patients who had a BMI ≥ 50. This risk plateaued after the first year and was equivalent to other weight classes afterward. Despite worse preoperative function and greater failure rates, this population reports major benefits and high satisfaction with THA. The risk of THA appears to be worth it for most patients who have a BMI ≥ 50.</p>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comparison of the Efficacy and Complications Between Intraosseous and Periarticular Multimodal Analgesic Cocktail Injections After Primary Total Knee Arthroplasty: A Randomized Controlled Trial. 首次全膝关节置换术后骨内和关节周围多模式鸡尾酒镇痛注射的疗效和并发症的比较:一项随机对照试验。
IF 3.8 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-18 DOI: 10.1016/j.arth.2025.12.026
Warunyoo Suttikadsanee, Parn Pinsornsak, Piya Pinsornsak

Background: Early postoperative pain control after total knee arthroplasty (TKA) plays a crucial role in patient satisfaction following surgery. Despite current multimodal pain management strategies, postoperative pain remains a concern for patients and can hinder the decision to undergo TKA. With the advent of intraosseous (IO) analgesic injections, the efficacy of IO multimodal analgesic cocktail administration compared to standard periarticular (PA) injections remains controversial.

Methods: A prospective randomized controlled trial was conducted comparing 45 patients who received an IO multimodal cocktail injection (five mg of morphine, 30 mg of ketorolac, 20 mL of 0.5% bupivacaine, and 0.6 mL of 1:1,000 epinephrine) with 45 patients who received a standard PA cocktail injection. A total of 43 patients in each group completed the study. Postoperative visual analog scale for pain at rest and during motion, morphine consumption, functional outcomes, and postoperative complications were recorded.

Results: In the IO group, visual analog scale for pain was significantly lower both at rest and during motion at four, six, and 12 hours, as well as two weeks postoperatively. The Timed Up and Go test was faster in the IO group at 48 hours, but not at two weeks. However, morphine consumption, time to start walking, time to discharge, postoperative range of motion, and complications showed no differences up to two weeks.

Conclusions: Intraosseous multimodal cocktail injection resulted in better pain control compared to PA injection during the early postoperative period, as well as improved function in the Timed Up and Go test at 48 hours after TKA, without increasing postoperative complications.

Level of evidence: Therapeutic Level I.

背景:全膝关节置换术(TKA)术后早期疼痛控制对术后患者满意度起着至关重要的作用。尽管目前的多模式疼痛管理策略,术后疼痛仍然是患者关注的问题,并可能阻碍接受TKA的决定。随着骨内(IO)镇痛注射的出现,与标准关节周(PA)注射相比,IO多模式鸡尾酒镇痛给药的疗效仍然存在争议。方法:采用前瞻性随机对照试验,将45例接受IO多模式鸡尾酒注射(吗啡5 mg、酮咯酸30 mg、0.5%布比卡因20 ml、1:10 00肾上腺素0.6 ml)的患者与45例接受标准PA鸡尾酒注射的患者进行比较。每组共有43名患者完成了研究。记录术后休息和运动时疼痛的视觉模拟评分(VAS)、吗啡用量、功能结局和术后并发症。结果:IO组术后4、6、12小时及2周休息和运动时疼痛VAS评分均明显降低。在48小时内,IO组的Timed Up and Go测试更快,但在两周内则不然。然而,吗啡用量、开始行走时间、出院时间、术后活动范围和并发症在两周内没有差异。结论:与关节周注射相比,术后早期骨内多模态鸡尾酒注射能更好地控制疼痛,TKA后48小时的Timed Up and Go测试功能得到改善,且未增加术后并发症。
{"title":"A Comparison of the Efficacy and Complications Between Intraosseous and Periarticular Multimodal Analgesic Cocktail Injections After Primary Total Knee Arthroplasty: A Randomized Controlled Trial.","authors":"Warunyoo Suttikadsanee, Parn Pinsornsak, Piya Pinsornsak","doi":"10.1016/j.arth.2025.12.026","DOIUrl":"10.1016/j.arth.2025.12.026","url":null,"abstract":"<p><strong>Background: </strong>Early postoperative pain control after total knee arthroplasty (TKA) plays a crucial role in patient satisfaction following surgery. Despite current multimodal pain management strategies, postoperative pain remains a concern for patients and can hinder the decision to undergo TKA. With the advent of intraosseous (IO) analgesic injections, the efficacy of IO multimodal analgesic cocktail administration compared to standard periarticular (PA) injections remains controversial.</p><p><strong>Methods: </strong>A prospective randomized controlled trial was conducted comparing 45 patients who received an IO multimodal cocktail injection (five mg of morphine, 30 mg of ketorolac, 20 mL of 0.5% bupivacaine, and 0.6 mL of 1:1,000 epinephrine) with 45 patients who received a standard PA cocktail injection. A total of 43 patients in each group completed the study. Postoperative visual analog scale for pain at rest and during motion, morphine consumption, functional outcomes, and postoperative complications were recorded.</p><p><strong>Results: </strong>In the IO group, visual analog scale for pain was significantly lower both at rest and during motion at four, six, and 12 hours, as well as two weeks postoperatively. The Timed Up and Go test was faster in the IO group at 48 hours, but not at two weeks. However, morphine consumption, time to start walking, time to discharge, postoperative range of motion, and complications showed no differences up to two weeks.</p><p><strong>Conclusions: </strong>Intraosseous multimodal cocktail injection resulted in better pain control compared to PA injection during the early postoperative period, as well as improved function in the Timed Up and Go test at 48 hours after TKA, without increasing postoperative complications.</p><p><strong>Level of evidence: </strong>Therapeutic Level I.</p>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Arthroplasty
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