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Treated unruptured cerebral aneurysm in elderly patients: a single center study 老年未破裂脑动脉瘤治疗:一项单中心研究
IF 1.6 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2023-12-14 DOI: 10.1016/j.neuchi.2023.101522
Thomas Metayer , Raphael Blanc , Stanislas Smajda , Jean Philippe Desilles , Hocine Redjem , Simon Escalard , Mikael Mazighi , Adnan Al Tayeb , Erwan Robichon , Amira Al Raaisi , William Boisseau , Francois Delvoye , Michel Piotin

Introduction

The increase in life expectancy raises the question of the treatment of unruptured intracranial aneurysms in extremely old patients (>80 years). We present results in terms of occlusion and complications in both symptomatic and asymptomatic aneurysm.

Methods

All patients aged >80 years admitted to the Foundation Adolphe de Rothschild between January 1, 2005 and March, 2023 were included. Aneurysms were grouped as compressive and non-compressive. Procedural complications were grouped as symptomatic (i.e., leading to any temporary or permanent neurological deficit) and severe (defined by modified Rankin Scale (mRS) ≥3 at follow-up).

Results

Forty-two aneurysms were treated in the study period. Coiling (with or without remodeling) was the treatment of choice in 30 patients. Eighteen patients had compressive aneurysm. Six complications occurred (14.2%), all ischemic. The majority of complications occurred in symptomatic aneurysms, in 4 patients (66.6%). One of the patients treated by flow-diverter had severe complications (mRs ≥3) with hemiplegia.

Conclusion

In extremely specific cases, treatment of unruptured aneurysm in people older than 80 years may be considered. Compressive aneurysm is associated with a high risk of complications. Treatments can be endovascular. Further prospective studies are required to confirm this hypothesis.

预期寿命的增加提出了对高龄患者(80岁)未破裂颅内动脉瘤治疗的问题。我们提出的结果,在闭塞和并发症的症状和无症状的动脉瘤。方法选取2005年1月1日至2023年3月在Adolphe de Rothschild基金会就诊的80岁患者。动脉瘤分为压缩性和非压缩性。手术并发症分为症状性(即导致任何暂时性或永久性神经功能缺损)和重度(随访时以改良Rankin量表(mRS)≥3定义)。结果本组共治疗42例动脉瘤。30例患者选择盘绕(伴或不伴重塑)作为治疗方法。18例患者有压缩性动脉瘤。并发症6例(14.2%),均为缺血性并发症。并发症主要发生在有症状的动脉瘤,4例(66.6%)。1例经分流治疗的患者出现严重并发症(mRs≥3)伴偏瘫。结论在特殊情况下,可考虑对80岁以上人群的未破裂动脉瘤进行治疗。压缩性动脉瘤与并发症的高风险相关。治疗可以在血管内进行。需要进一步的前瞻性研究来证实这一假设。
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引用次数: 0
Effects of indirect foraminal decompression during anterior cervical disc fusion procedure: preliminary results of a prospective study with clinical and radiological outcomes 颈椎椎间盘前路融合术期间间接椎间孔减压的效果:临床和放射学结果前瞻性研究的初步结果
IF 1.6 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2023-12-12 DOI: 10.1016/j.neuchi.2023.101523
Lainé G. , Coudert P. , Damade C. , Boissiere L. , Pointillart V. , Vital J.M. , Bouyer B. , Gille O.

Introduction

The respective effects of direct and indirect decompression in the clinical outcome after anterior cervical disc fusion (ACDF) is still debated. The main purpose of this study was to analyze the effects of indirect decompression on foraminal volumes during ACDF performed in patients suffering from cervico-brachial neuralgias due to degenerative foraminal stenosis, i.e. to determine whether implant height was associated with increased postoperative foraminal height and volume.

Methods

A prospective follow-up of patients who underwent ACDF for cervicobrachial neuralgias due to degenerative foraminal stenosis was conducted. Patient had performed a CT-scan pre and post-operatively. Disc height, foraminal heights and foraminal volumes were measured pre and post operatively.

Results

37 cervical disc fusions were successfully performed in 20 patients, with a total of 148 foramina studied. Foraminal height and volume were measured bilaterally on the pre- and post-operative CT scans (148 foramina studied). After univariate analysis, it was found a significant improvement for every radiological parameter, with a significant increase in disc height, foraminal height and foraminal volume being respectively +3,22 mm (p < 0,001), +2,12 mm (p < 0,001) and +54 mm3 (p < 0,001). Increase in disc height was significantly associated with increase in foraminal height (p < 0,001) and foraminal volume (p < 0,001). At the same time, increase in foraminal height was significantly correlated with foraminal volume (p < 0,001), and seems to be the major component affecting increasing in foraminal volume.

Conclusion

Indirect decompression plays an important part in the postoperative foraminal volume increase after ACDF performed for cervicobrachial neuralgias.

引言 直接减压和间接减压对颈椎间盘前路融合术(ACDF)术后临床效果的影响仍存在争议。本研究的主要目的是分析在对因退行性椎间孔狭窄导致的颈臂神经痛患者实施 ACDF 过程中,间接减压对椎间孔容积的影响,即确定植入物的高度是否与术后椎间孔高度和容积的增加有关。患者在术前和术后均接受了 CT 扫描。结果20名患者成功实施了37例颈椎间盘融合术,共研究了148个椎孔。术前和术后 CT 扫描测量了双侧椎管的高度和容积(共研究了 148 个椎管)。经过单变量分析,发现每个放射学参数都有显著改善,椎间盘高度、椎孔高度和椎孔容积分别显著增加了+3,22 mm (p < 0,001)、+2,12 mm (p < 0,001)和+54mm3 (p < 0,001)。椎间盘高度的增加与椎管高度(p < 0,001)和椎管容积(p < 0,001)的增加明显相关。同时,椎间孔高度的增加与椎间孔容积(p < 0,001)明显相关,似乎是影响椎间孔容积增加的主要因素。
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引用次数: 0
Pseudoaneurysm formation after placement of a FRED flow diverter stent in a patient with iatrogenic ICA injury during transsphenoidal surgery: A case report 一名在经蝶窦手术中先天性 ICA 损伤的患者在置入 FRED 分流支架后形成假性动脉瘤:病例报告
IF 1.6 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2023-12-05 DOI: 10.1016/j.neuchi.2023.101520
Mohammad Hasanpour , Navid Golchin , Hojjat Mirsardoo , Ahmad Alagha , Daniel Elyassirad , Ehsan Keykhosravi
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引用次数: 0
Internal carotid artery injury during endoscopic transsphenoidal pituitary surgery: risk factors, management 经蝶窦垂体内窥镜手术中颈动脉损伤:危险因素及处理
IF 1.6 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2023-12-04 DOI: 10.1016/j.neuchi.2023.101515
Xin Ma , Yu Zhang , Zhi-Jun Yang , Bo Wang , Xin-Chao Wang , Chao Zhang , Pi-Nan Liu , Zhi-Yong Bi

Background

Transsphenoidal surgeons should try to avoid internal carotid artery (ICA) injury but also be prepared to manage it. We analyzed our experience with ICA injury during endoscopic transsphenoidal pituitary surgery and present associated risk factors and a management protocol.

Methods

We retrospectively reviewed and analyzed the medical records of 1596 patients who underwent endoscopic transsphenoidal surgery for pituitary tumor resection in our institution from January 2009 to October 2022.

Results

Six patients experienced an ICA injury. All received timely and effective hemostasis with immediate direct tamponade followed by endovascular treatment. No serious postoperative complications occurred.

Conclusions

We proposed a treatment plan for ICA injuries encountered during endoscopic transsphenoidal surgery and described our hemostasis process, methods of endovascular treatment, and means of postoperative follow-up in detail.

背景:经蝶窦外科医生应尽量避免颈内动脉(ICA)损伤,但也要准备好处理它。我们分析了内镜下经蝶窦垂体手术中ICA损伤的经验,并提出了相关的危险因素和处理方案。方法回顾性分析我院2009年1月至2022年10月1596例经蝶窦内镜下垂体瘤切除术患者的病历。结果6例患者发生ICA损伤。所有患者均及时有效止血,立即直接填塞,然后进行血管内治疗。术后未发生严重并发症。结论我们提出了内镜下经蝶窦手术中ICA损伤的治疗方案,并详细描述了我们的止血过程、血管内治疗方法和术后随访方式。
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引用次数: 0
Modified orbitozygomatic craniotomy with a single burr hole in the alternative sphenoid ridge keyhole 改良眶颧骨开颅术,在蝶骨脊锁孔上加单刺孔
IF 1.6 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2023-12-03 DOI: 10.1016/j.neuchi.2023.101514
Semyon A. Melchenko , Grigorii E. Golodnev , Vasiliy A. Cherekaev , Albert A. Sufianov , Marat R. Gizatullin , Denis A. Golbin , Nikolay V. Lasunin , Ivan S. Sheliagin , Artem A. Surikov , Ilya V. Senko

Background

One-piece modified orbitozygomatic approach (OZA) is an extended version of the pterional approach that also includes orbital walls and frontal process of the zygomatic bone. For this craniotomy one burr hole must be placed in MacCarty keyhole and another - in the temporal region.

Objective

To develop a technique of the one-piece modified OZA with single a burr hole in the alternative sphenoid ridge keyhole that allows access to orbit, anterior cranial fossa and middle cranial fossa and apply it intraoperatively.

Methods

A single human head specimen was used. The dissection was performed using standard surgical instruments high-speed Stryker drill. Every stage of the approach was photographed. We also report a surgical case of a patient with orbital cavernous hemangioma that was resected using the described technique.

Results

The technique of the one-piece modified OZA with a single burr hole in the alternative sphenoid ridge keyhole is described, and its advantages and limitations are analyzed. The technique is used to totally resect an orbital cavernous hemangioma with good functional and cosmetic result.

Conclusion

Modified OZA with a single burr hole in the sphenoid ridge keyhole is possible and may be an alternative to the classic technique. The advantages of this variation are the placement of just one burr hole and the preservation of a larger portion of the orbital roof. The latter facilitates better bone reconstruction and better cosmetic outcome. Disadvantages are the difficulty of identifying the location of the sphenoid ridge keyhole and risk of damaging the dura.

背景:完成片改良眶颧入路(OZA)是翼点入路的扩展版本,也包括眶壁和颧骨额突。对于这种开颅术,一个钻孔必须放置在麦卡蒂锁眼上,另一个钻孔必须放置在颞区。目的探讨一种可进入眼眶、颅前窝和颅中窝的单孔蝶脊锁孔一体式改良OZA技术,并在术中应用。方法采用单个人头标本。采用标准手术器械,高速Stryker钻头进行解剖。接近的每个阶段都被拍了下来。我们也报告一例眶海绵状血管瘤的手术病例,采用上述技术切除。结果介绍了一种改进型单毛刺孔单件式蝶骨脊锁孔技术,并分析了其优点和局限性。该技术用于眼眶海绵状血管瘤的完全切除,具有良好的功能和美容效果。结论改良OZA在蝶脊锁眼内加单毛刺孔是可行的,可作为经典技术的替代方法。这种变化的优点是只放置一个毛刺孔和保存眶顶的较大部分。后者有助于更好的骨重建和更好的美容效果。缺点是难以确定蝶骨脊锁孔的位置,并且有损伤硬脑膜的危险。
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引用次数: 0
A narrative review of techniques for surgical revascularization of the extracranial vertebral artery in vertebrobasilar insufficiency 椎基底动脉功能不全的颅外椎动脉外科血运重建技术综述。
IF 1.6 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2023-11-23 DOI: 10.1016/j.neuchi.2023.101516
Laura Stone McGuire, Fady T. Charbel

Vertebrobasilar insufficiency is a condition characterized by poor blood flow through the posterior circulation of the brain, which supplies the brainstem, thalamus, hippocampus, cerebellum, occipital lobes, and medial temporal lobes. Narrowing or occlusion of the vertebral arteries may be result in a range of neurological symptoms, including dizziness, imbalance, dysarthria, and even stroke. If symptomatic patients fail medical management, revascularization of the vertebral artery should be considered. Restoration of blood flow may involve transluminal balloon angioplasty or stent placement; however, certain cases may still require surgical intervention. The complexity of surgical revascularization of the vertebral artery requires careful consideration of skull base and neck anatomy. This review article will focus on bypass of the vertebral artery in the setting of ischemic pathology, describing the technique, anatomical nuances, steps involved in preoperative planning, and postoperative management.

椎基底动脉功能不全是一种以脑干、丘脑、海马、小脑、枕叶和内侧颞叶的后循环供血不足为特征的疾病。椎动脉狭窄或闭塞可导致一系列神经系统症状,包括头晕、失衡、构音障碍,甚至中风。如果有症状的患者治疗失败,应考虑椎动脉血运重建。血流的恢复可能涉及腔内球囊血管成形术或支架置入;然而,某些病例可能仍需要手术干预。椎动脉外科血运重建的复杂性需要仔细考虑颅底和颈部解剖。这篇综述文章将聚焦于缺血病理背景下的椎动脉搭桥术,描述技术、解剖上的细微差别、术前计划和术后处理的步骤。
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引用次数: 0
Super acute subdural hematoma following drain removal for chronic subdural haematoma 慢性硬膜下血肿引流术后超急性硬膜下血肿
IF 1.6 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2023-11-15 DOI: 10.1016/j.neuchi.2023.101510
Charles Champeaux Depond, Dahmane El Hairech, Philippe Metellus
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引用次数: 0
A narrative review of techniques for surgical revascularization of the extracranial vertebral artery in vertebrobasilar insufficiency 椎基底动脉功能不全手术颅内外椎动脉血运重建术的综述
IF 1.6 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2023-11-09 DOI: 10.1016/j.neuchi.2023.101512
Laura Stone McGuire, Fady T. Charbel

Vertebrobasilar insufficiency is a condition characterized by poor blood flow through the posterior circulation of the brain, which supplies the brainstem, thalamus, hippocampus, cerebellum, occipital lobes, and medial temporal lobes. Narrowing or occlusion of the vertebral arteries may be result in a range of neurological symptoms, including dizziness, imbalance, dysarthria, and even stroke. If symptomatic patients fail medical management, revascularization of the vertebral artery should be considered. Restoration of blood flow may involve transluminal balloon angioplasty or stent placement; however, certain cases may still require surgical intervention. The complexity of surgical revascularization of the vertebral artery requires careful consideration of skull base and neck anatomy. This review article will focus on bypass of the vertebral artery in the setting of ischemic pathology, describing the technique, anatomical nuances, steps involved in preoperative planning, and postoperative management.

椎基底动脉功能不全是一种以脑干、丘脑、海马、小脑、枕叶和内侧颞叶的后循环供血不足为特征的疾病。椎动脉狭窄或闭塞可导致一系列神经系统症状,包括头晕、失衡、构音障碍,甚至中风。如果有症状的患者治疗失败,应考虑椎动脉血运重建。血流的恢复可能涉及腔内球囊血管成形术或支架置入;然而,某些病例可能仍需要手术干预。椎动脉外科血运重建的复杂性需要仔细考虑颅底和颈部解剖。这篇综述文章将聚焦于缺血病理背景下的椎动脉搭桥术,描述技术、解剖上的细微差别、术前计划和术后处理的步骤。
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引用次数: 0
Hemangioblastomas of the cauda equina: Clinical features and long-term surgical outcomes 马尾血管母细胞瘤:临床特征和长期手术结果。
IF 1.6 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2023-11-04 DOI: 10.1016/j.neuchi.2023.101513
Bo Han , Liang Zhang , Wenqing Jia

Background

Spinal hemangioblastomas (HBs) that involving cauda equina are rare. Data on clinical characteristics and long-term intervention outcomes of patients harboring cauda equina HBs remain lacking due to its scarcity.

Objective

This study aims to present the clinical-radiological features and treatment results of this rare pathology by using cases from a single center.

Methods

A review of demographic data and intervention outcomes of patients harboring cauda equina HBs in our department between 2009 and 2020 was retrospectively carried out.

Results

Ten consecutive adult patients were incorporated, with a slight female predominance (n = 6, 60%). The mean age was 39.9 ± 14.7 (range: 18–58) years. Six patients (60%) had von Hippel‒Lindau (VHL) syndrome and showed multiple symptoms and severe neurological deficits, while 4 (40%) were in the sporadic group and only presented pain symptoms. During follow-up, 3 patients (30%) experienced lesion relapse and underwent repeated surgery. Favorable outcomes were achieved in all patients.

Conclusion

Cauda equina HBs are rare spinal vascular lesions that should be differentiated from other lumbar canal lesions. Total surgical resection is the main treatment modality and can benefit patients, even recurrent patients. The treatment outcome is usually satisfactory, especially in sporadic cases.

背景:累及马尾神经的脊髓血管母细胞瘤是罕见的。由于缺乏关于携带马尾HBs的患者的临床特征和长期干预结果的数据,因此仍然缺乏。目的:本研究旨在通过单个中心的病例介绍这种罕见病理的临床放射学特征和治疗结果。方法:回顾性分析2009年至2020年我科携带马尾HBs患者的人口学数据和干预结果。结果:连续10例成年患者被纳入,其中女性略占优势(n = 60%)。平均年龄39.9岁 ± 14.7(范围:18-58)岁。6名患者(60%)患有von Hippel-Lindau(VHL)综合征,表现出多种症状和严重的神经功能缺损,而4名患者(40%)属于散发组,仅表现出疼痛症状。在随访期间,3名患者(30%)出现病变复发并接受了反复手术。所有患者都取得了良好的结果。结论:马尾HBs是一种罕见的脊髓血管病变,应与其他椎管病变鉴别。全手术切除是主要的治疗方式,可以使患者受益,甚至使复发患者受益。治疗结果通常是令人满意的,尤其是在散发病例中。
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引用次数: 0
Corrigendum to “A2B5-positive oligodendrocyte precursor cell transplantation improves neurological deficits in rats following spinal cord contusion associated with changes in expression of factors involved in the Notch signaling pathway” [Neurochirurgie 68 (2) (2022) 188–95] 更正“A2B5阳性少突胶质细胞前体细胞移植可改善脊髓挫伤后大鼠的神经功能缺损,该损伤与Notch信号通路相关因子的表达变化有关”[Neurochirgie 68(2)(2022)188-95]。
IF 1.6 4区 医学 Q4 CLINICAL NEUROLOGY Pub Date : 2023-11-04 DOI: 10.1016/j.neuchi.2023.101481
H. Yuan , C.-L. Fang , Y.-P. Deng , J. Huang , R.-Z. Niu , J.-L. Chen , T.-B. Chen , Z.-Q. Zhu , L. Chen , L.-L. Xiong , T.-H. Wang
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引用次数: 0
期刊
Neurochirurgie
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