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Virtual diversity and the value-ladenness of science
IF 3 2区 社会学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-01-30 DOI: 10.1177/03063127251314860
Charles Thorpe
Collins, Evans, and Reyes-Galindo develop the concept of interactional expertise into the idea of virtual diversity. They thereby provide a strong case against the epistemic barriers established by identity politics. This commentary questions, however, whether virtual diversity can incorporate the critique of institutional power that Wynne has argued is at the center of tensions between lay publics and scientific establishments. The commentary argues for a critical theory of science, as suggested by Doppelt on the basis of his normative interpretation of Kuhnian incommensurability.
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引用次数: 0
Silence of the labs.
IF 2.9 2区 社会学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-01-22 DOI: 10.1177/03063127251314452
Banu Subramaniam

This is a commentary on 'Virtual diversity: Resolving the tension between the wider culture and the institution of science', by Harry Collins, Robert Evans, Luis Reyes-Galindo.

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引用次数: 0
The commercial roots of the genomic commons 基因组公地的商业根源
IF 3 2区 社会学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-01-18 DOI: 10.1177/03063127241310122
Steve Sturdy
Accounts of the origins of the genomic commons typically focus on the development of public repositories and data-sharing agreements. This article tells a different story. During the 1990s in the United States, efforts of private companies to prevent the patenting of certain kinds of DNA sequences were essentially a conservative response to shifts in the sociotechnical constitution of the pharmaceutical innovation system, and to the operation of intellectual property as one of the key knowledge control regimes that regulate that system. In this context, the idea of ‘the commons’ was rehabilitated from earlier tragic theorizations to argue that industry’s ability to deliver new pharmaceutical products would be better served if certain kinds of intellectual property were left in the public domain. The genomic commons is not a neutral space of disinterested scientific research that naturally aligns with some abstract ‘public good’, but is part of an innovation system that has evolved to serve the interests of a range of stakeholders, among which the big pharmaceutical companies enjoy a dominant position.
对基因组公地起源的描述通常集中在公共存储库和数据共享协议的发展上。这篇文章讲述了一个不同的故事。在20世纪90年代的美国,私营公司努力阻止某些种类的DNA序列的专利实质上是对制药创新系统的社会技术构成的转变的保守反应,以及对知识产权作为规范该系统的关键知识控制制度之一的运作的保守反应。在这种背景下,“公地”的概念从早期的悲剧性理论中恢复过来,认为如果某些类型的知识产权留在公共领域,工业提供新药品的能力将得到更好的服务。基因组公地不是一个无私的科学研究的中立空间,自然地与一些抽象的“公共利益”保持一致,而是一个创新系统的一部分,它已经演变为服务于一系列利益相关者的利益,其中大型制药公司享有主导地位。
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引用次数: 0
From the bench to public policy: Enhancing public trust in science. 从法官到公共政策:增强公众对科学的信任。
IF 2.9 2区 社会学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-01-13 DOI: 10.1177/03063127241310587
Shobita Parthasarathy

There is growing concern around the world about declining trust in the scientific enterprise. Some STS scholars argue that the solution is to move to a system of 'virtual diversity' where scientists are responsible for translating public concerns into their work. This commentary argues that this containment approach will have the opposite effect. The history of similar efforts suggests that scientists have trouble understanding the scope and urgency of public frustrations, and devalue the contributions of non-scientists, damaging the social fabric. A better approach for producing socially useful science and enhancing public trust is to create a truly inclusive scientific enterprise, which takes the knowledge and priorities of non-scientists seriously and engages them throughout the investigative process.

全世界越来越担心人们对科学事业的信任度下降。一些STS学者认为,解决方案是转向一种“虚拟多样性”的系统,在这种系统中,科学家负责将公众关注的问题转化为他们的工作。这篇评论认为,这种遏制措施将产生相反的效果。类似努力的历史表明,科学家很难理解公众挫折感的范围和紧迫性,并且贬低了非科学家的贡献,破坏了社会结构。生产对社会有用的科学和增强公众信任的更好方法是创建一个真正包容的科学企业,认真对待非科学家的知识和优先事项,并在整个调查过程中让他们参与。
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引用次数: 0
Coordinating uncertainty in the political economy of cyber threat intelligence. 协调网络威胁情报政治经济中的不确定性。
IF 2.9 2区 社会学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-01-10 DOI: 10.1177/03063127241299132
Rebecca Slayton, Lilly Muller

Cyber threat intelligence firms play a powerful role in producing knowledge, uncertainty, and ignorance about threats to organizations and governments globally. Drawing on historical and ethnographic methods, we show how cyber threat intelligence analysts navigate distinctive types of uncertainty as they transform digital traces into marketable products and services. We make two related contributions and arguments. First, building on STS research on uncertainty and ignorance, we articulate two kinds of uncertainty and their potential to interact. Coordinative uncertainty emerges from socially and technologically distributed processes of producing, interpreting, and reporting data that emerges when analysts create standards to make data travel. However, standards can be exploited by intelligent adversaries behaving in deliberately unpredictable ways. We argue that efforts to reduce coordinative uncertainty through standardization can thus ironically increase opportunities for adversarial uncertainty, creating a potential tradeoff. Second, we aim to show how STS can deepen and integrate studies of international security and political economy, by providing an example of how the geopolitical structuring of private industry shapes the science and technology that industry produces. In particular, we argue that the political economy of the cyber threat intelligence industry tends to produce relatively little knowledge about cyber operations that are conducted by governments in the U.S. and its allies, and more about cyber operations conducted by adversaries of U.S. and allied governments. We conclude with a reflection on the broader significance of these findings for the ways that coordinative and adversarial uncertainties refract through the political economies of technoscience.

网络威胁情报公司在制造对全球组织和政府威胁的知识、不确定性和无知方面发挥着强大的作用。利用历史和民族志方法,我们展示了网络威胁情报分析师如何在将数字痕迹转化为可销售的产品和服务时导航不同类型的不确定性。我们有两个相关的贡献和论点。首先,基于STS对不确定性和无知的研究,我们阐明了两种不确定性及其相互作用的潜力。当分析人员创建数据传输标准时,协调不确定性出现在生产、解释和报告数据的社会和技术分布式过程中。然而,标准可以被聪明的对手利用,以故意不可预测的方式行事。我们认为,通过标准化减少协调不确定性的努力可能会讽刺地增加对抗性不确定性的机会,从而产生潜在的权衡。其次,我们的目标是通过提供一个私营工业的地缘政治结构如何塑造工业生产的科学和技术的例子,展示STS如何深化和整合国际安全和政治经济学的研究。特别是,我们认为,网络威胁情报行业的政治经济学倾向于对美国及其盟国政府进行的网络行动产生相对较少的了解,而对美国及其盟国政府的对手进行的网络行动则有更多的了解。最后,我们反思了这些发现对通过技术科学的政治经济学折射出的协调和对抗性不确定性的方式的更广泛意义。
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引用次数: 0
Making expert advice public in a time of emergency: Independent SAGE and the contestation of science during the Covid pandemic in the UK. 在紧急情况下公开专家建议:独立的SAGE和英国Covid大流行期间的科学争论。
IF 2.9 2区 社会学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-01-10 DOI: 10.1177/03063127241309071
Noortje Marres, Matías Valderrama Barragán

This article presents a situational analysis of the expert advice offered by Independent SAGE, a group of scientists that formed in May 2020 in the UK to provide advice on the Covid response. Based on interviews with the group's members and partners, we argue that through its interventions Indie SAGE demonstrated an important alternative approach to linking science and politics in a time of emergency. They showed that the only way to ensure that policy and decision-making on Covid-19 was grounded in knowledge was by making expert advice public. Indie SAGE's decision to 'go public' was a response to the political situation in the UK, one in which scientific advice, in particular public health expertise, was being ignored, sidelined and contested as such. We identify four rationales for making expert advice public: openness, calling out, translation, and responsive engagement. We describe associated modes of intervention that Indie SAGE adopted in relation to different critical situations of Covid-19. Distinctive about their advice, we argue, is its prioritization of situational adequacy. Much of it was explicitly oriented towards addressing practical and existential challenges experienced by particular social groups, professions and everyday publics. We argue that this way of making science public in an 'ontological' register acquires critical importance in a political situation like the UK Covid response, which was marked not just by disagreements about science but growing contestation of science as such. In this respect, our study holds a wider lesson for the understanding of the role of evidence in public politics. To advocate for evidence-based governance, as Indie SAGE did, is not necessarily to endorse a post-political vision of government. When science is contested in a time of emergency, making evidence public becomes a key means for responding to the demands of situations. It is not only pragmatic but a critical accomplishment.

本文对独立SAGE提供的专家建议进行了情景分析,该专家组于2020年5月在英国成立,旨在为应对Covid提供建议。根据对该小组成员和合作伙伴的采访,我们认为,通过其干预措施,Indie SAGE展示了在紧急情况下将科学与政治联系起来的重要替代方法。他们表明,确保Covid-19政策和决策建立在知识基础上的唯一途径是公开专家建议。Indie SAGE“上市”的决定是对英国政治局势的回应,在这种政治局势中,科学建议,特别是公共卫生专业知识,被忽视、边缘化和争议。我们确定了公开专家建议的四个基本原则:开放、呼吁、翻译和响应性参与。我们描述了独立SAGE针对Covid-19的不同危急情况采取的相关干预模式。我们认为,他们的建议的独特之处在于其对情境充分性的优先考虑。其中很大一部分明确面向解决特定社会群体、职业和日常公众所面临的实际和存在的挑战。我们认为,这种以“本体论”的方式公开科学的方式,在像英国应对新冠肺炎这样的政治局势中具有至关重要的意义,英国应对新冠肺炎的特点不仅是对科学的分歧,而且是对科学本身日益激烈的争论。在这方面,我们的研究为理解证据在公共政治中的作用提供了更广泛的经验。正如Indie SAGE所做的那样,提倡基于证据的治理并不一定支持后政治的政府愿景。当科学在紧急情况下受到质疑时,公开证据成为应对形势要求的关键手段。这不仅是务实的,而且是一项重要的成就。
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引用次数: 0
Can democracy save children's lives? Addressing the constitutional problem of expertise. 民主能拯救儿童的生命吗?解决专业知识的宪法问题。
IF 2.9 2区 社会学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-01-06 DOI: 10.1177/03063127241310461
Brice Laurent

This comment critically examines Collins, Evans, and Reyes-Galindo's (CE&RG) concept of 'virtual diversity', proposed as a norm to safeguard scientific expertise in policy-making. CE&RG argue that scientists should acquire 'interactional expertise' in relevant 'non-scientific domains', enabling informed policy advice while preserving scientific integrity. This comment describes CE&RG's dualist approach, which separates epistemic and political concerns, and discusses its implications. It shows that for virtual diversity to contribute to the quality of and trust in expertise, this approach needs to be radically re-worked to include legitimacy-building processes. Using examples such as South Africa's AIDS policy and the COVID-19 pandemic, the comment argues that defending expertise requires ensuring the robustness of both scientific and political representations, of, in other terms, addressing expertise as a constitutional problem. Without a broader critical constitutional analysis, CE&RG's proposal risks reinforcing the crisis of expertise it seeks to remedy.

本评论对柯林斯、埃文斯和雷耶斯-加林多(CE&RG)提出的 "虚拟多样性 "概念进行了批判性研究。CE&RG 认为,科学家应掌握相关 "非科学领域 "的 "互动专业知识",从而在维护科学完整性的同时,为政策提供明智的建议。本评论介绍了 CE&RG 的二元论方法,即把认识论和政治问题分开,并讨论了其影响。它表明,要使虚拟多样性有助于提高专业知识的质量和信任度,就需要对这一方法进行彻底改革,将合法性建设过程纳入其中。评论以南非的艾滋病政策和 COVID-19 大流行病为例,认为捍卫专业知识需要确保科学和政治表述的稳健性,换句话说,需要将专业知识作为一个宪法问题来解决。如果不对宪法进行更广泛的批判性分析,CE&RG 的建议有可能会强化其试图补救的专业知识危机。
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引用次数: 0
Right data, wrong data: Statistical sampling and the making of modern agriculture in India. 正确的数据,错误的数据:统计抽样和印度现代农业的形成。
IF 2.9 2区 社会学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-01-06 DOI: 10.1177/03063127241307947
Madhumita Saha

The size of India's food deficit became a pressing question for the Indian state in the early years of independence. As different organizations, government bodies, and individuals debated over the ways, means, and expertise needed to tide over the food crisis, policymakers realized that the primary requirement was to have a numerical understanding of the problem. Data became crucial to accurately assess production trends and compare them with requirements. This article looks into the use of statistical methods, particularly, random sampling and production estimation through a crop-cutting technique. Exploring the statistical survey work done by P.C. Mahalanobis in Bengal from the late years of colonial rule to the surveys conducted by the Indian Council of Agricultural Research under the supervision of P.V. Sukhatme and V.G. Panse, the article analyzes how different factors, such as varying revenue systems of different regions and administrative structures, power struggles amongst statisticians, and leverage gained by Indian statisticians from support they received from better known British counterparts, all played a role in determining the nature of statistical tools adopted in India to measure its food production. Inaccurate data continued to be a challenge for the Indian state until well into the late 1950s, and that can now be explained in terms of this discord between Mahalanobis-led Kolkata-ISI and the ICAR of Sukhatme's time. India continued to follow different methods of statistical survey of foodcrops, thus, the scientific/political establishment always struggled with the apprehension that they did not have the 'right' data to come up with the correct assessment of the scene.

在印度独立的最初几年,粮食短缺的规模成为印度政府面临的一个紧迫问题。当不同的组织、政府机构和个人就渡过粮食危机所需的方式、手段和专业知识进行辩论时,政策制定者意识到,首要要求是对问题有一个数字上的理解。数据对于准确评估生产趋势并将其与需求进行比较至关重要。本文探讨了统计方法的应用,特别是随机抽样和通过作物切割技术进行产量估计。本文探讨了P.C. Mahalanobis从殖民统治末期到印度农业研究委员会在P.V. Sukhatme和V.G. Panse的监督下所做的统计调查工作,分析了不同地区和行政结构的不同收入制度、统计学家之间的权力斗争等不同因素如何影响统计研究的发展。以及印度统计学家从更知名的英国同行那里获得的支持所获得的杠杆作用,都在决定印度采用统计工具来衡量其粮食生产的性质方面发挥了作用。直到20世纪50年代末,不准确的数据一直是印度政府面临的一个挑战,现在可以用mahalanobis领导的加尔各答isi和苏哈特梅时代的ICAR之间的分歧来解释。印度继续采用不同的粮食作物统计调查方法,因此,科学/政治机构总是担心他们没有“正确”的数据来对现场进行正确的评估。
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引用次数: 0
Postcolonial technoscience revisited. 重新审视后殖民技术科学。
IF 2.9 2区 社会学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-12-16 DOI: 10.1177/03063127241303778
Cameron Hu

What does a postcolonial inquiry into technoscience do? And what is it for? I develop these questions by reconsidering one powerful idea: that science and technology studies (STS) is postcolonial when it elucidates the hybridity, heterogeneity, and indeterminacy of global technoscientific formations, and does so to falsify colonial fantasies of hegemony expressed in imperious conceptual generalities and sovereign universalisms. Revisiting Warwick Anderson's expositions of postcolonial STS-initiated in this journal two decades ago-I reflect on the form and force of this critical operation. Despite an animating aversion to universalisms, the pursuit of hybridity and heterogeneity may ultimately universalize a liberal metaphysics of agency. This paradox suggests limits to the critical operation that pits hybridity and indeterminacy against hegemony in a postcolonial spirit.

对技术科学的后殖民主义探究是做什么的?又是为了什么?我通过重新考虑一个强有力的观点来阐释这些问题:科学技术研究(STS)在阐明全球技术科学形态的混合性、异质性和不确定性时,就是后殖民主义的,这样做的目的是为了篡改以强制性的概念概括和主权普遍主义表达的殖民霸权幻想。重温沃里克-安德森(Warwick Anderson)二十年前在本刊发表的关于后殖民科技创新的论述,我反思了这一批判行动的形式和力量。尽管人们对普遍主义深恶痛绝,但对混杂性和异质性的追求最终可能会使自由主义的代理形而上学普遍化。这一悖论表明,以后殖民精神将混杂性和不确定性与霸权对立起来的批判行动是有局限性的。
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引用次数: 0
A precision immuno-oncology turn? Hybridizing cancer genomics and immunotherapy through neoantigens-based adoptive cell therapies 精准免疫肿瘤学转向?杂交癌症基因组学和免疫疗法通过新抗原为基础的过继细胞疗法
IF 3 2区 社会学 Q1 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-12-16 DOI: 10.1177/03063127241303720
Luca Chiapperino, Nils Graber, Francesco Panese
This article explores the development of T cell-based therapies in Switzerland. These therapies, which elicit the immunological potential of each patient to respond to tumor development, constitute a major promise for so-called ‘precision oncology’. We document how immunological concepts, technologies, and practices are articulated given the centrality of genomics in ‘precision oncology’. We consider ‘precision immunotherapies’ to probe whether and how change ensues in these established sociotechnical regimes of biomedicine. The case of genomics and immunology in oncology offers a unique insight into the conditions of possibility for change in such regimes. How does the present new wave of cancer immunotherapies challenge, integrate, and complement the centrality of genomics in ‘precision oncology’? What are the specific processes that make possible the convergence, competition, or co-existence of distinct conceptions, infrastructures, and programs of innovative cancer medicine? Drawing from observations and interviews with researchers and clinicians, we qualify these sociotechnical processes as hybridizations. Bringing together different sociotechnical regimes of biomedical research is conditional to the articulation of core concepts, technologies, and translational practices of genomics and immunology. Pivotal to this objective are neoantigens, cell surface proteins originating from the somatic genetic mutations of tumors and which activate a patient’s immune response. While neoantigens are an unstable entity in experimentation, they offer a conceptual and material substrate to renegotiate the dominance of cancer genomics, and initiate the production of a new, hybrid regime of ‘immunogenomic precision’ in oncology.
这篇文章探讨了T细胞疗法在瑞士的发展。这些疗法可以激发每个患者的免疫潜能,对肿瘤的发展做出反应,这对所谓的“精确肿瘤学”来说是一个重大的承诺。我们记录了免疫学概念、技术和实践是如何在“精确肿瘤学”基因组学的中心地位下得到阐述的。我们考虑“精确免疫疗法”来探索这些已建立的生物医学社会技术制度是否以及如何发生变化。肿瘤学基因组学和免疫学的案例提供了一个独特的见解,以改变这种制度的可能性条件。当前癌症免疫疗法的新浪潮如何挑战、整合和补充基因组学在“精确肿瘤学”中的中心地位?创新癌症医学的不同概念、基础设施和项目的融合、竞争或共存的具体过程是什么?根据对研究人员和临床医生的观察和访谈,我们将这些社会技术过程定性为杂交。汇集生物医学研究的不同社会技术制度是有条件的核心概念,技术,以及基因组学和免疫学的转化实践的衔接。实现这一目标的关键是新抗原,即源自肿瘤体细胞基因突变的细胞表面蛋白,它能激活患者的免疫反应。虽然新抗原在实验中是一个不稳定的实体,但它们为重新协商癌症基因组学的主导地位提供了概念和物质基础,并启动了肿瘤学中“免疫基因组学精确”的新混合体制的生产。
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引用次数: 0
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Social Studies of Science
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