South African Journal of Psychiatry最新文献_第3页

South African mental healthcare providers' views about exercise for people with mental illness. 南非精神医疗服务提供者对精神病患者锻炼的看法。

IF 1 4区医学 Q3 Medicine

South African Journal of Psychiatry

Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.4102/sajpsychiatry.v30i0.2227

Belinda S Marais

Background: People living with mental illness (PWMI) have significantly reduced life expectancy compared to the general population, yet mental healthcare providers (MHCPs) do not regularly prescribe exercise, despite its proven health benefits.

Aim: This study aimed to evaluate South African MHCPs' views regarding exercise for PWMI.

Setting: A cross-sectional descriptive study conducted across five public sector specialised psychiatric units in Gauteng.

Methods: Mental healthcare providers were surveyed using the Exercise in Mental Illness Questionnaire - Health Professionals Version.

Results: Most participants were nurses (49.1%) and doctors (26.2%) and reported no prior formal training in exercise prescription (79.4%). The vast majority (up to 89.7%) agreed regarding the physical benefits of exercise, particularly cardiometabolic benefits. The most common barriers, as perceived by MHCPs, to exercise participation for PWMI were: stigma (56.5%) and medication side effects (56.5%). The majority (76.2%) reported prescribing exercise for PWMI at least 'occasionally'. The method most frequently used was personal discussion (77.3%) and aerobic exercise was most frequently recommended (81.0%). Specific instructions regarding physical activity recommendations however were often not provided. Regarding MHCPs personal exercise habits, only a third (34%) met physical activity guidelines. Most MHCPs (92.1%) indicated an interest in further training regarding exercise for PWMI.

Conclusion: Mental healthcare providers were supportive of exercise for PWMI. Strategies to address the stigma around mental illness and medication side-effects, to improve training regarding exercise prescription, as well as the exercise habits of MHCPs themselves, and collaboration with exercise professionals and organisations are recommended.

Contribution: This study provides insight into the views of South African MHCPs regarding exercise for PWMI.

背景：与普通人相比，精神疾病患者的预期寿命明显缩短，尽管运动对健康有益，但精神医疗服务提供者（MHCPs）并不经常开具运动处方：在豪滕省的五个公共部门精神病专科进行的横断面描述性研究：方法：使用精神疾病运动问卷--卫生专业人员版对精神卫生保健提供者进行调查：结果：大多数参与者是护士（49.1%）和医生（26.2%），并称之前未接受过运动处方方面的正规培训（79.4%）。绝大多数人（高达 89.7%）认同运动对身体的益处，尤其是对心脏代谢的益处。医疗保健人员认为，残疾人参与运动最常见的障碍是：耻辱感（56.5%）和药物副作用（56.5%）。大多数医疗保健人员（76.2%）表示至少 "偶尔 "为残疾人开具运动处方。最常用的方法是个人讨论（77.3%），最常推荐的是有氧运动（81.0%）。然而，他们往往没有提供有关体育锻炼建议的具体指导。关于健康保健医生的个人运动习惯，只有三分之一（34%）符合体育锻炼指南。大多数精神卫生保健提供者（92.1%）表示有兴趣接受有关残疾人运动的进一步培训：结论：精神卫生保健提供者支持针对残疾人的运动。结论：精神健康医疗服务提供者支持针对残疾人的运动，建议采取以下策略来解决与精神疾病和药物副作用相关的污名化问题，改善运动处方方面的培训以及精神健康医疗服务提供者自身的运动习惯，并与运动专业人士和组织合作：本研究有助于深入了解南非精神健康保健医生对残疾人运动的看法。

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引用次数: 0

Lived experience narrative: My journey with schizophrenia. 生活经历叙事：我的精神分裂症之旅

IF 1 4区医学 Q3 Medicine

South African Journal of Psychiatry

Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.4102/sajpsychiatry.v30i0.2259

引用次数: 0

Introducing the 'Lived Experience' section of the South African Journal of Psychiatry. 介绍《南非精神病学杂志》的 "生活经历 "栏目。

IF 1 4区医学 Q3 Medicine

South African Journal of Psychiatry

Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.4102/sajpsychiatry.v30i0.2268

Laila Asmal, Mehita Iqani

引用次数: 0

Suicidal behaviour among patients with congestive cardiac failure in a Nigerian teaching hospital 尼日利亚一家教学医院充血性心力衰竭患者的自杀行为

IF 1 4区医学 Q3 Medicine

South African Journal of Psychiatry

Pub Date : 2024-04-23 DOI: 10.4102/sajpsychiatry.v30i0.2204

Tomilola O. Shofu-Akanji, Bolanle Ola, D. Adegbaju, A. Ajibare, Adefemi A. Adeoye, Ismail O. Adesina

Background: Suicidal behaviour is an established psychiatric complication of congestive cardiac failure (CCF), contributing significantly to morbidity and death by suicide. The magnitude and risk factors for suicidal behaviour among patients with CCF are yet to be unpacked, especially in developing nations such as Nigeria.Aim: To determine the prevalence of suicidal behaviour and the risk factors associated with suicidal behaviour, among patients with CCF in Nigeria.Setting: Cardiology outpatient clinic of Lagos State University Teaching Hospital, Lagos, Nigeria.Methods: A cross-sectional study was conducted among 98 randomly selected patients with a diagnosis of CCF. Participants were assessed with a socio-demographic and clinical factors questionnaire and Beck Scale of Suicidal Ideation. Chi-square test, t-test and logistic regression were used to analyse data.Results: The prevalence of suicidal ideation and suicidal attempt among patients with CCF was 52% and 1%, respectively. No socio-demographic factor was significantly associated with suicidal ideation. Clinical factors associated with suicidal ideation were age at diagnosis (p = 0.042), aetiology of CCF (p = 0.001) and severity of CCF (p = 0.032). Only the severity of CCF (odds ratio [OR] = 20.557, p = 0.014) predicted suicidal ideation among patients with CCF.Conclusion: Suicidal behaviour constitutes a huge burden among the outpatient CCF population. The identification of clinical risk factors for suicidal ideation (age at diagnosis, aetiology and severity of CCF) further illuminates a pathway to mortality among patients with CCF.Contribution: The findings lend a voice to the need for screening for suicidal behaviour, suicide prevention programmes, surveillance systems and government policies that support mental health for patients with CCF.

背景：自杀行为是充血性心力衰竭（CCF）的一种公认的精神并发症，是导致自杀发病和死亡的重要原因。充血性心力衰竭患者自杀行为的严重程度和风险因素尚待研究，尤其是在尼日利亚等发展中国家：地点：尼日利亚拉各斯拉各斯州立大学教学医院心脏病学门诊：方法：对随机抽取的 98 名确诊为 CCF 的患者进行横断面研究。通过社会人口学和临床因素问卷以及贝克自杀意念量表对参与者进行了评估。采用卡方检验、t检验和逻辑回归分析数据：结果：在CCF患者中，自杀意念和自杀未遂的发生率分别为52%和1%。没有任何社会人口因素与自杀意念显著相关。与自杀意念相关的临床因素有诊断时的年龄（p = 0.042）、CCF 的病因（p = 0.001）和 CCF 的严重程度（p = 0.032）。只有CCF的严重程度（几率比[OR] = 20.557，p = 0.014）能预测CCF患者的自杀意念：结论：自杀行为是CCF门诊患者的一大负担。自杀意念的临床风险因素（CCF 的诊断年龄、病因和严重程度）的确定进一步揭示了导致 CCF 患者死亡的途径：研究结果说明，有必要对CCF患者进行自杀行为筛查、实施自杀预防计划、建立监控系统并制定支持心理健康的政府政策。

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引用次数: 0

Factors associated with long hospitalisation for psychotic disorder patients in an acute ward: Tertiary care hospital 急症病房精神病患者长期住院的相关因素：三级护理医院

IF 1 4区医学 Q3 Medicine

South African Journal of Psychiatry

Pub Date : 2024-04-23 DOI: 10.4102/sajpsychiatry.v30i0.2049

Tshepiso I. Paliweni-Zwane, Lucas N. Modisane, G. Grobler

Background: The average length of stay is often used to indicate health system efficiency; shorter stays are associated with reduced costs. In South Africa, mental healthcare expenditure is spent on inpatient care.Aim: To identify factors associated with a long stay in an acute psychiatric unit.Setting: A tertiary hospital.Methods: A case-control study review of inpatients diagnosed with psychotic symptoms was used. Sample was divided into two groups, length of stay (LOS) (LOS greater than 21 days, LOS less than 14 days). Total of 82 patients were divided into short stay group (SSG, n = 23) and long stay group (LSG) (n = 59). A comparison of demographic, clinical and system variables was conducted.Results: In demographics, LSG had fewer men compared to SSG (78.3%) and differed statistically from LSG with p = 0.05. Long stay groups were older in comparison to SSG with a p = 0.02. Illicit substance use in LSG was 44.1% and statistically less than SSG (73.91%; p = 0.02). A high proportion of LSG had medical or surgical and psychiatric comorbidities (67.8%) compared to SSG (43.5%) (p = 0.04). A total of 95% patients in SSG had family support.Conclusion: Longer stay was found to be associated with older females with primary psychotic disorders. Comorbidities with less availability of family support were associated with younger males presenting with psychotic symptoms that may be related to illicit substances that respond to rapid stabilisation.Contribution: Active surveillance of medical comorbidities amongst older female patients is necessary for early liaison services to reduce their length of stay.

背景：平均住院时间通常用来衡量医疗系统的效率；住院时间越短，成本越低。在南非，精神疾病的医疗支出主要用于住院治疗。目的：确定与急性精神病科长期住院相关的因素：环境：一家三级医院：方法：对确诊有精神病症状的住院患者进行病例对照研究。样本按住院时间（LOS）分为两组（LOS大于21天，LOS小于14天）。共有 82 名患者被分为短期住院组（SSG，n = 23）和长期住院组（LSG，n = 59）。对人口统计学、临床和系统变量进行了比较：在人口统计学方面，LSG 组的男性人数少于 SSG 组（78.3%），且在统计学上与 LSG 组存在差异（P = 0.05）。与 SSG 相比，长期住院组的年龄更大，P = 0.02。长期住院组使用非法药物的比例为 44.1%，在统计学上低于长期住院组（73.91%；P = 0.02）。与 SSG（43.5%）相比，LSG 中患有内科、外科和精神科并发症的比例较高（67.8%）（p = 0.04）。SSG中95%的患者有家庭支持：结论：老年女性原发性精神病患者的住院时间较长。合并症和较少家庭支持与出现精神症状的年轻男性有关，这些症状可能与非法药物有关，并对快速稳定病情有反应：贡献：有必要对老年女性患者的合并症进行积极监测，以便及早提供联络服务，缩短住院时间。

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引用次数: 0

Nurses’ practice of metabolic monitoring for patients on antipsychotics in Lesotho 莱索托护士对服用抗精神病药物的患者进行代谢监测的做法

IF 1 4区医学 Q3 Medicine

South African Journal of Psychiatry

Pub Date : 2024-04-22 DOI: 10.4102/sajpsychiatry.v30i0.2219

Relebohile P. Matete, L. Rathobei

Background: Severe mental illness is associated with higher physical health morbidities and reduced life expectancy, with an estimated 14.3% of global deaths attributed to mental disorders. Antipsychotic medications (APs) used in treatment contribute to physical health issues, including metabolic and cardiovascular effects.Aim: The aim of this study was to assess nurses’ practices regarding metabolic monitoring for patients prescribed antipsychotic medications at Mohlomi Hospital in Lesotho.Setting: The study was conducted at Mohlomi Hospital, the primary psychiatric facility in Lesotho.Methods: Using a cross-sectional design, 44 nurses from Mohlomi Hospital participated in the study. A structured questionnaire assessed nurses’ metabolic monitoring practices.Results: Most of the respondents were female (n = 30, 75%), and minority were male (n = 10, 25%). The academic qualifications of respondents were distributed as follows: 40% (16) held a nursing assistant certificate and 22.5% (9) held an advanced nursing diploma, among others. The average age of all respondents was 39.05 (s.d. 8.9), with an average of 8 years of experience in psychiatry (s.d. 7.6). The overall rate of nurses’ practices of metabolic monitoring for patients taking antipsychotic medications showed variability, with a mean score of 2.83 (s.d. 0.524). However, only 20% performed ECG tests, 22.5% measured blood pressure, 27.5% tested for glucose abnormalities and 17.5% conducted lipid profile testing.Conclusion: Results revealed a significant gap in the practice of metabolic monitoring among nurses with various aspects of metabolic monitoring, not being adequately monitored.Contribution: The study’s findings shall inform policy and guidelines for monitoring patients on antipsychotic medications while guiding future research.

背景：严重的精神疾病与较高的身体健康发病率和预期寿命缩短有关，据估计，全球14.3%的死亡归因于精神障碍。研究目的：本研究旨在评估莱索托莫赫罗米医院护士在对处方抗精神病药物的患者进行代谢监测方面的做法：研究在莱索托的主要精神病院莫赫罗米医院进行：44名来自莫赫罗米医院的护士参与了研究。一份结构化问卷对护士的代谢监测实践进行了评估：大多数受访者为女性（30 人，占 75%），少数为男性（10 人，占 25%）。受访者的学历分布如下：40%（16 人）持有护理助理证书，22.5%（9 人）持有高级护理文凭等。所有受访者的平均年龄为 39.05 岁（标准差为 8.9），平均从事精神科工作 8 年（标准差为 7.6）。护士对服用抗精神病药物的患者进行代谢监测的总体比例存在差异，平均得分为 2.83（标准差为 0.524）。然而，只有 20% 的护士进行了心电图检测，22.5% 的护士测量了血压，27.5% 的护士检测了血糖异常，17.5% 的护士进行了血脂检测：结果表明，护士在代谢监测方面的实践存在很大差距，代谢监测的各个方面都没有得到充分监测：贡献：研究结果将为监测服用抗精神病药物患者的政策和指南提供参考，同时为今后的研究提供指导。

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引用次数: 0

Schizophrenia and schizoaffective disorder: Length of stay and associated factors 精神分裂症和分裂情感障碍：住院时间和相关因素

IF 1 4区医学 Q3 Medicine

South African Journal of Psychiatry

Pub Date : 2024-04-22 DOI: 10.4102/sajpsychiatry.v30i0.2237

Ladawa Y. Goga, B. Marais

Background: Patients with schizophrenia and schizoaffective disorder often require longer admissions.Aim: To explore length of stay (LOS) and associated factors of patients with schizophrenia and schizoaffective disorder, admitted to a public sector specialised psychiatric hospital, over a 4-year period.Setting: The study was conducted at Tara Hospital in Johannesburg.Methods: A retrospective record review of 367 adult schizophrenia and schizoaffective disorder patients admitted between 01 January 2015 and 31 December 2018. Average LOS was calculated and the proportion of short-stay ( 30 days), medium-stay (31–90 days) and long-stay ( 90 days) admissions determined. Sociodemographic, clinical and admission outcome data were collected and analysed from a randomly selected subset of patients in each LOS category.Results: Mean LOS was 128 days (median 87, interquartile range [IQR] 49–164, range 0–755 days). A significantly greater proportion had long-stay admissions (p 0.001). Male gender (p = 0.018), being unmarried (p = 0.006), treatment resistant (p 0.001) and on clozapine (p = 0.009) were factors found to have a significant association with long-stay admissions. Rates of unemployment ( 80%), comorbid substance use disorders ( 40%), medical illnesses ( 40%), antipsychotic polypharmacy ( 40%) and readmissions ( 80%) were high. Most ( 80%) were discharged.Conclusion: Long-stay admissions were frequently required for patients with schizophrenia and schizoaffective disorder admitted to Tara Hospital.Contribution: This study highlights factors associated with long-stay admissions in patients with schizophrenia and schizoaffective disorder. More research is needed into whether increased access to community-based services, such as residential and daycare facilities, outpatient substance rehabilitation programmes and dual diagnosis clinics, could translate into shorter admissions, less frequent relapses and improved outcomes in this population.

背景：精神分裂症和情感分裂症患者通常需要较长的入院时间：目的：探讨一家公立精神病专科医院四年来收治的精神分裂症和情感分裂症患者的住院时间（LOS）及相关因素：研究在约翰内斯堡的塔拉医院进行：对2015年1月1日至2018年12月31日期间收治的367名成年精神分裂症和分裂情感障碍患者进行回顾性记录审查。计算平均住院日，并确定短期住院（30 天）、中期住院（31-90 天）和长期住院（90 天）的比例。从每个住院时间类别中随机抽取一组患者，收集并分析其社会人口学、临床和入院结果数据：平均住院日为 128 天（中位数 87 天，四分位数间距 [IQR] 49-164 天，范围 0-755 天）。长期住院患者的比例明显更高（P 0.001）。研究发现，男性（p = 0.018）、未婚（p = 0.006）、耐药（p 0.001）和服用氯氮平（p = 0.009）等因素与长期住院有显著关联。失业率（80%）、合并药物使用障碍（40%）、内科疾病（40%）、服用抗精神病药物（40%）和再入院率（80%）都很高。大多数患者（80%）已经出院：结论：塔拉医院收治的精神分裂症和分裂情感障碍患者经常需要长期住院：本研究强调了精神分裂症和情感分裂症患者长期住院的相关因素。我们需要开展更多的研究，以了解更多的社区服务（如寄宿和日托设施、门诊物质康复计划和双重诊断诊所）是否能缩短住院时间、减少复发频率并改善这类人群的治疗效果。

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引用次数: 0

Nigeria mental health law: Challenges and implications for mental health services 尼日利亚精神卫生法：心理健康服务面临的挑战和影响

IF 1 4区医学 Q3 Medicine

South African Journal of Psychiatry

Pub Date : 2024-04-19 DOI: 10.4102/sajpsychiatry.v30i0.2134

G. O. Ozota, Ruth N. Sabastine, Franklin C. Uduji, Vanessa C. Okonkwo

Background: The Nigerian mental health law titled the Lunacy Act of 1958 has been under scrutiny for violating the human rights of people with mental illness. The call to reform the obsolete Lunacy Act has garnered attention from the government, as the law has been unamended for over 60 years.Aim: This study presents the challenges and implications of the new mental health law to the mental health services of Nigeria.Methods: ScienceDirect, PubMed, and Google Scholar were used to find pertinent material. The implications and difficulties facing the new mental health law examined from the literature were discussed. Recommendations were made following an exploratory search for literature on mental health legislation in Nigeria.Results: The new Law in Section 5(6) saw the introduction of mental health services in primary and secondary healthcare. It also addresses critical issues such as non-discrimination, fundamental human rights, standards of treatment, access to information, confidentiality and autonomy, and the employment rights of persons with mental health and substance abuse-related disorders. The Law failed to include mental health services in the country’s health insurance system.Conclusion: There is a need for legislation to meet people’s mental health needs and encourage them to seek treatments, such as regulations that protect against discrimination and harsh treatment of people with mental illness.Contribution: Nigerian mental health services would benefit from the new mental health law if the key issues raised in this review are addressed.

背景：名为 1958 年《癫狂法》的尼日利亚精神卫生法因侵犯精神病患者的人权而备受关注。目的：本研究介绍了新精神卫生法对尼日利亚精神卫生服务的挑战和影响：方法：使用 ScienceDirect、PubMed 和 Google Scholar 查找相关资料。方法：使用 ScienceDirect、PubMerm 和 Google 学术搜索相关资料，讨论了文献中研究的新精神卫生法的影响和面临的困难。在对尼日利亚精神卫生立法文献进行探索性搜索后，提出了相关建议：新法第 5（6）条规定在初级和中级医疗保健中引入心理健康服务。它还解决了一些关键问题，如不歧视、基本人权、治疗标准、信息获取、保密性和自主性，以及精神疾病患者和药物滥用相关疾病患者的就业权利。该法未能将精神健康服务纳入国家医疗保险体系：结论：有必要通过立法来满足人们的心理健康需求并鼓励他们寻求治疗，例如制定相关法规，防止歧视和苛待精神病患者：贡献：如果本报告中提出的关键问题得到解决，尼日利亚的心理健康服务将从新的心理健康法中受益。

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引用次数: 0

Demographic and mental health profile of youth in a gender service: An African case series 性别服务中青年的人口和心理健康概况：非洲案例系列

IF 1 4区医学 Q3 Medicine

South African Journal of Psychiatry

Pub Date : 2024-04-17 DOI: 10.4102/sajpsychiatry.v30i0.2160

Simon D. Pickstone-Taylor, E. L. Davids, Graham N. De Bever, Petrus J. De Vries

Background: Despite a massive global increase in research on gender-diverse youth, there have been no studies in Africa on gender-diverse children and adolescents presenting to health services.Aim: This study aimed to present the first African findings of the demographic and mental health profile of youth who have presented at a gender service in South Africa.Setting: A specialist mental health outpatient service, consisting of psychiatry, psychology and nursing input, for gender-diverse child and adolescent patients in the Western Cape.Methods: All consenting youth seen at a gender service, consisting of psychiatry, psychology and nursing input, in state and by the same clinician in private practice between January 2012 and May 2019 were participants of a retrospective, sequential case series study. Data of interest, including gender identity and sexuality, mental health history and social information, were extracted from the psychiatry files of participants.Results: Thirty-nine participants were part of the registry and qualified for the study: 72% self-identified as white, 15% as coloured and 13% as black African. The rate of co-occurring psychopathology was high (64%) and included high rates of autism, particularly in trans males (26%), suicidal ideation in 31% and a history of suicide attempt(s) in 10%.Conclusions: This first study describing gender-diverse youth seeking support relating to their gender identity in Africa showed they had remarkable similarities to those studied internationally.Contribution: Establishing that transgender youth of all major racial groups in the province with similar demographic profiles to other parts of the world are presenting to services in South Africa and in need of mental health support and interventions.

背景：尽管全球范围内对性别多元化青少年的研究大量增加，但在非洲，还没有关于前来医疗服务机构就诊的性别多元化儿童和青少年的研究：地点：南非西开普省的一家专科心理健康门诊服务机构，该机构由精神病学、心理学和护理学组成，主要为性别多元化的儿童和青少年患者提供服务：方法：2012年1月至2019年5月期间，所有同意在由精神病学、心理学和护理学组成的性别服务机构就诊的青少年均参与了一项回顾性、连续性病例系列研究。研究人员从参与者的精神病学档案中提取了相关数据，包括性别认同和性行为、心理健康史和社会信息：39 名参与者是登记册的一部分，符合研究条件：72%的参与者自我认定为白人，15%为有色人种，13%为非洲黑人。合并精神病理学的比例很高（64%），其中自闭症的比例很高，尤其是变性男性（26%），31%的人有自杀倾向，10%的人有自杀未遂史：这项研究首次描述了在非洲寻求与性别认同相关支持的不同性别青年的情况，表明他们与国际上研究的对象有显著的相似之处：贡献：研究表明，在南非，该省所有主要种族群体中的变性青年都向心理健康服务机构求助，并需要心理健康支持和干预。

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引用次数: 0

Comparing the medication costs of treating patients with schizophrenia who use cannabis with those who do not 比较治疗使用大麻和不使用大麻的精神分裂症患者的药物成本

IF 1 4区医学 Q3 Medicine

South African Journal of Psychiatry

Pub Date : 2024-04-15 DOI: 10.4102/sajpsychiatry.v30i0.2211

Nikhil Nowbath, Nada Abdelatif, Gian Lippi

Background: Cannabis use is more prevalent among people with schizophrenia than in the general population. This usage detrimentally impacts disease prognosis, contributing to escalated admissions, heightened severity of psychotic symptoms, and reduced medication response. The recent decriminalisation of cannabis in South Africa may lead to an upsurge in usage, consequently intensifying the strain on mental healthcare services.Aim: This study aimed to compare the medication costs of patients with schizophrenia depending on cannabis use.Setting: Weskoppies Hospital, Pretoria, South Africa, 2018–2019.Methods: Data pertaining to medication expenses during the 2018–2019 period were acquired from the hospital pharmacy. Data were collected from 114 patient records to form two equal cohorts: one exposed to cannabis and the other non-exposed, as indicated by urine drug screens or admission of cannabis use. Medications prescribed from admission to time of being ready for discharge were recorded and corresponding costs were calculated.Results: Patients who were exposed to cannabis had higher medication costs (R 516.47) than patients who were non-exposed (R 328.69) (p = 0.0519), over the whole admission period.Conclusion: Cannabis exposure escalates the financial burden of treating schizophrenia at Weskoppies Hospital. This might be attributed to failure of cost-effective, first-line medications prompting the prescription of costlier, second-line alternatives or higher prescribed dosages.Contribution: This study contributes to findings that it is more expensive to treat patients with schizophrenia who have relapsed, if they are using cannabis. This finding has future cost implications when budgeting for pharmacotherapeutic treatment.

背景：与普通人群相比，精神分裂症患者吸食大麻的情况更为普遍。吸食大麻会对疾病预后产生不利影响，导致入院人数增加、精神症状更加严重以及药物反应减弱。最近，南非不再将大麻视为犯罪，这可能会导致大麻使用量激增，从而加剧精神医疗服务的压力。目的：本研究旨在比较精神分裂症患者因使用大麻而产生的药物费用：2018-2019年南非比勒陀利亚Weskoppies医院：从医院药房获取2018-2019年期间的药费数据。从 114 份患者记录中收集数据，形成两个相等的队列：一个队列暴露于大麻，另一个队列未暴露于大麻，以尿液药物筛查或承认使用大麻为标志。记录了从入院到准备出院期间的处方药，并计算了相应的费用：结果：在整个入院期间，接触过大麻的患者的药费（R 516.47）高于未接触过大麻的患者（R 328.69）（p = 0.0519）：结论：接触大麻会加重韦斯科皮斯医院治疗精神分裂症的经济负担。这可能是由于成本效益高的一线药物治疗失败，促使患者开出成本更高的二线替代药物或更高的处方剂量：本研究有助于发现，治疗复发的精神分裂症患者时，如果他们使用大麻，治疗费用会更高。这一发现对今后编制药物治疗预算具有成本影响。

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引用次数: 0