首页 > 最新文献

Statistical Papers最新文献

英文 中文
Dimension reduction-based adaptive-to-model semi-supervised classification 基于降维的自适应模型半监督分类法
IF 1.3 3区 数学 Q2 STATISTICS & PROBABILITY Pub Date : 2024-05-30 DOI: 10.1007/s00362-024-01578-6
Xuehu Zhu, Rongzhu Zhao, Dan Zeng, Qian Zhao, Jun Zhang

This paper introduces a novel Dimension Reduction-based Adaptive-to-model Semi-supervised Classification method, specifically designed for scenarios where the number of unlabeled samples significantly exceeds that of labeled samples. Leveraging the strengths of sufficient dimension reduction and non-parametric interpolation, the method significantly amplifies the value derived from unlabeled samples, thus enhancing the precision of the classification model. An iterative version is also presented to extract further insights from the interpolated unlabeled samples. Theoretical analyses and numerical studies demonstrate substantial improvements in classifier accuracy, particularly in the context of model misspecified. The effectiveness of the proposed method in enhancing classification accuracy is further substantiated through two empirical analyses: credit card application evaluations and coronary heart disease diagnostic assessments.

本文介绍了一种新颖的基于降维的自适应模型半监督分类方法,该方法专门针对未标注样本数量大大超过标注样本数量的情况而设计。利用充分的维度缩减和非参数插值的优势,该方法能显著放大来自未标记样本的价值,从而提高分类模型的精度。该方法还提出了一个迭代版本,以便从插值的非标记样本中获得更多的启示。理论分析和数值研究表明,分类器的精确度有了大幅提高,尤其是在模型未定义的情况下。通过信用卡申请评估和冠心病诊断评估这两项实证分析,进一步证实了所提方法在提高分类准确性方面的有效性。
{"title":"Dimension reduction-based adaptive-to-model semi-supervised classification","authors":"Xuehu Zhu, Rongzhu Zhao, Dan Zeng, Qian Zhao, Jun Zhang","doi":"10.1007/s00362-024-01578-6","DOIUrl":"https://doi.org/10.1007/s00362-024-01578-6","url":null,"abstract":"<p>This paper introduces a novel Dimension Reduction-based Adaptive-to-model Semi-supervised Classification method, specifically designed for scenarios where the number of unlabeled samples significantly exceeds that of labeled samples. Leveraging the strengths of sufficient dimension reduction and non-parametric interpolation, the method significantly amplifies the value derived from unlabeled samples, thus enhancing the precision of the classification model. An iterative version is also presented to extract further insights from the interpolated unlabeled samples. Theoretical analyses and numerical studies demonstrate substantial improvements in classifier accuracy, particularly in the context of model misspecified. The effectiveness of the proposed method in enhancing classification accuracy is further substantiated through two empirical analyses: credit card application evaluations and coronary heart disease diagnostic assessments.</p>","PeriodicalId":51166,"journal":{"name":"Statistical Papers","volume":"83 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141191719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On weighted version of dynamic cumulative residual inaccuracy measure based on extropy 基于外熵的动态累积残差误差测量的加权版本
IF 1.3 3区 数学 Q2 STATISTICS & PROBABILITY Pub Date : 2024-05-25 DOI: 10.1007/s00362-024-01568-8
Morteza Mohammadi, Majid Hashempour

This paper introduces the concept of dynamic cumulative residual extropy inaccuracy (DCREI) by expanding on the existing dynamic cumulative residual extropy (DCRE) measure and proposes a weighted version of it. The paper then investigates a characterization problem for the proposed weighted dynamic extropy inaccuracy measure under the proportional hazard model and characterizes some well-known lifetime distributions using the weighted dynamic cumulative residual extropy inaccuracy (WDCREI) measure. Additionally, the study discusses the stochastic ordering of WDCREI and certain results based on it. Non-parametric estimations of the proposed measures based on kernel and empirical estimators are suggested. Results of a simulation study show that the kernel-based estimators perform better than the empirical-based estimator. Finally, applications of the proposed measures on model selection are provided.

本文通过扩展现有的动态累积残余外熵不准确度(DCRE)度量,引入了动态累积残余外熵不准确度(DCREI)的概念,并提出了其加权版本。然后,本文研究了所提出的加权动态外熵不准确度在比例危险模型下的表征问题,并使用加权动态累积残余外熵不准确度 (WDCREI) 表征了一些著名的寿命分布。此外,研究还讨论了 WDCREI 的随机排序和基于它的某些结果。研究还提出了基于核估计器和经验估计器的非参数估计方法。模拟研究结果表明,基于核的估计方法比基于经验的估计方法表现更好。最后,还介绍了所提方法在模型选择中的应用。
{"title":"On weighted version of dynamic cumulative residual inaccuracy measure based on extropy","authors":"Morteza Mohammadi, Majid Hashempour","doi":"10.1007/s00362-024-01568-8","DOIUrl":"https://doi.org/10.1007/s00362-024-01568-8","url":null,"abstract":"<p>This paper introduces the concept of dynamic cumulative residual extropy inaccuracy (DCREI) by expanding on the existing dynamic cumulative residual extropy (DCRE) measure and proposes a weighted version of it. The paper then investigates a characterization problem for the proposed weighted dynamic extropy inaccuracy measure under the proportional hazard model and characterizes some well-known lifetime distributions using the weighted dynamic cumulative residual extropy inaccuracy (WDCREI) measure. Additionally, the study discusses the stochastic ordering of WDCREI and certain results based on it. Non-parametric estimations of the proposed measures based on kernel and empirical estimators are suggested. Results of a simulation study show that the kernel-based estimators perform better than the empirical-based estimator. Finally, applications of the proposed measures on model selection are provided.</p>","PeriodicalId":51166,"journal":{"name":"Statistical Papers","volume":"9 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141153701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A non-classical parameterization for density estimation using sample moments 利用样本矩进行密度估计的非经典参数化方法
IF 1.3 3区 数学 Q2 STATISTICS & PROBABILITY Pub Date : 2024-05-20 DOI: 10.1007/s00362-024-01563-z
Guangyu Wu, Anders Lindquist

Probability density estimation is a core problem in statistics and data science. Moment methods are an important means of density estimation, but they are generally strongly dependent on the choice of feasible functions, which severely affects the performance. In this paper, we propose a non-classical parametrization for density estimation using sample moments, which does not require the choice of such functions. The parametrization is induced by the squared Hellinger distance, and the solution minimizing it, which is proved to exist and be unique subject to a simple prior that does not depend on data, and which can be obtained by convex optimization. Statistical properties of the density estimator, together with an asymptotic error upper bound, are proposed for the estimator by power moments. Simulation results validate the performance of the estimator by a comparison to several prevailing methods. The convergence rate of the proposed estimator is proved to be (m^{-1/2}) (m being the number of data samples), which is the optimal convergence rate for parametric estimators and exceeds that of the nonparametric estimators. To the best of our knowledge, the proposed estimator is the first one in the literature for which the power moments up to an arbitrary even order exactly match the sample moments, while the true density is not assumed to fall within specific function classes.

概率密度估计是统计学和数据科学的核心问题。矩方法是密度估计的一种重要手段,但它通常严重依赖于可行函数的选择,这严重影响了其性能。在本文中,我们提出了一种利用样本矩进行密度估计的非经典参数化方法,它不需要选择此类函数。参数化由平方海灵格距离和最小化海灵格距离的解诱导,该解被证明是存在的,并且在不依赖于数据的简单先验条件下是唯一的,可以通过凸优化获得。针对幂矩估计法,提出了密度估计法的统计特性以及渐近误差上限。通过与几种常用方法的比较,仿真结果验证了估计器的性能。事实证明,所提估计器的收敛速率为(m^{-1/2})(m 为数据样本数),这是参数估计器的最佳收敛速率,并且超过了非参数估计器的收敛速率。据我们所知,所提出的估计器是文献中第一个幂矩直到任意偶数阶都与样本矩完全匹配的估计器,而真实密度并不假定属于特定的函数类别。
{"title":"A non-classical parameterization for density estimation using sample moments","authors":"Guangyu Wu, Anders Lindquist","doi":"10.1007/s00362-024-01563-z","DOIUrl":"https://doi.org/10.1007/s00362-024-01563-z","url":null,"abstract":"<p>Probability density estimation is a core problem in statistics and data science. Moment methods are an important means of density estimation, but they are generally strongly dependent on the choice of feasible functions, which severely affects the performance. In this paper, we propose a non-classical parametrization for density estimation using sample moments, which does not require the choice of such functions. The parametrization is induced by the squared Hellinger distance, and the solution minimizing it, which is proved to exist and be unique subject to a simple prior that does not depend on data, and which can be obtained by convex optimization. Statistical properties of the density estimator, together with an asymptotic error upper bound, are proposed for the estimator by power moments. Simulation results validate the performance of the estimator by a comparison to several prevailing methods. The convergence rate of the proposed estimator is proved to be <span>(m^{-1/2})</span> (<i>m</i> being the number of data samples), which is the optimal convergence rate for parametric estimators and exceeds that of the nonparametric estimators. To the best of our knowledge, the proposed estimator is the first one in the literature for which the power moments up to an arbitrary even order exactly match the sample moments, while the true density is not assumed to fall within specific function classes.</p>","PeriodicalId":51166,"journal":{"name":"Statistical Papers","volume":"57 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141153313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geometric infinitely divisible autoregressive models 几何无限可分自回归模型
IF 1.3 3区 数学 Q2 STATISTICS & PROBABILITY Pub Date : 2024-05-20 DOI: 10.1007/s00362-024-01564-y
Monika S. Dhull, Arun Kumar

In this article, we discuss some geometric infinitely divisible (gid) random variables using the Laplace exponents which are Bernstein functions and study their properties. The distributional properties and limiting behavior of the probability densities of these gid random variables at (0^{+}) are studied. The autoregressive (AR) models with gid marginals are introduced. Further, the first order AR process is generalized to kth order AR process. We also provide the parameter estimation method based on conditional least square and method of moments for the introduced AR(1) process. We also apply the introduced AR(1) model with geometric inverse Gaussian marginals on the household energy usage data which provide a good fit as compared to normal AR(1) data.

本文利用伯恩斯坦函数的拉普拉斯指数讨论了一些几何无限可分(gid)随机变量,并研究了它们的性质。研究了这些gid随机变量在(0^{+})处的概率密度的分布性质和极限行为。引入了具有 gid 边值的自回归(AR)模型。此外,还将一阶 AR 过程泛化为 kth 阶 AR 过程。我们还为引入的 AR(1) 过程提供了基于条件最小二乘法和矩法的参数估计方法。我们还将引入的具有几何反高斯边际的 AR(1) 模型应用于家庭能源使用数据,与普通 AR(1) 数据相比,该模型具有良好的拟合效果。
{"title":"Geometric infinitely divisible autoregressive models","authors":"Monika S. Dhull, Arun Kumar","doi":"10.1007/s00362-024-01564-y","DOIUrl":"https://doi.org/10.1007/s00362-024-01564-y","url":null,"abstract":"<p>In this article, we discuss some geometric infinitely divisible (gid) random variables using the Laplace exponents which are Bernstein functions and study their properties. The distributional properties and limiting behavior of the probability densities of these gid random variables at <span>(0^{+})</span> are studied. The autoregressive (AR) models with gid marginals are introduced. Further, the first order AR process is generalized to <i>k</i>th order AR process. We also provide the parameter estimation method based on conditional least square and method of moments for the introduced AR(1) process. We also apply the introduced AR(1) model with geometric inverse Gaussian marginals on the household energy usage data which provide a good fit as compared to normal AR(1) data.</p>","PeriodicalId":51166,"journal":{"name":"Statistical Papers","volume":"5 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141153300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Variation comparison between infinitely divisible distributions and the normal distribution 无限可分分布与正态分布的变异比较
IF 1.3 3区 数学 Q2 STATISTICS & PROBABILITY Pub Date : 2024-05-10 DOI: 10.1007/s00362-024-01561-1
Ping Sun, Ze-Chun Hu, Wei Sun

Let X be a random variable with finite second moment. We investigate the inequality: (P{|X-textrm{E}[X]|le sqrt{textrm{Var}(X)}}ge P{|Z|le 1}), where Z is a standard normal random variable. We prove that this inequality holds for many familiar infinitely divisible continuous distributions including the Laplace, Gumbel, Logistic, Pareto, infinitely divisible Weibull, Log-normal, Student’s t and Inverse Gaussian distributions. Numerical results are given to show that the inequality with continuity correction also holds for some infinitely divisible discrete distributions.

假设 X 是一个具有有限第二矩的随机变量。我们研究不等式(P{|X-textrm{E}[X]|le sqrt{textrm{Var}(X)}}ge P{|Z|le 1}),其中 Z 是标准正态随机变量。我们证明了这个不等式对许多熟悉的无限可分连续分布都成立,包括拉普拉斯分布、甘贝尔分布、对数分布、帕累托分布、无限可分韦布尔分布、对数正态分布、Student's t 分布和反高斯分布。给出的数值结果表明,带连续性修正的不等式也适用于某些无限可分离散分布。
{"title":"Variation comparison between infinitely divisible distributions and the normal distribution","authors":"Ping Sun, Ze-Chun Hu, Wei Sun","doi":"10.1007/s00362-024-01561-1","DOIUrl":"https://doi.org/10.1007/s00362-024-01561-1","url":null,"abstract":"<p>Let <i>X</i> be a random variable with finite second moment. We investigate the inequality: <span>(P{|X-textrm{E}[X]|le sqrt{textrm{Var}(X)}}ge P{|Z|le 1})</span>, where <i>Z</i> is a standard normal random variable. We prove that this inequality holds for many familiar infinitely divisible continuous distributions including the Laplace, Gumbel, Logistic, Pareto, infinitely divisible Weibull, Log-normal, Student’s <i>t</i> and Inverse Gaussian distributions. Numerical results are given to show that the inequality with continuity correction also holds for some infinitely divisible discrete distributions.</p>","PeriodicalId":51166,"journal":{"name":"Statistical Papers","volume":"3 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140925479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multivariate stochastic comparisons of sequential order statistics with non-identical components 具有非相同成分的序列阶次统计的多变量随机比较
IF 1.3 3区 数学 Q2 STATISTICS & PROBABILITY Pub Date : 2024-05-07 DOI: 10.1007/s00362-024-01558-w
Tanmay Sahoo, Nil Kamal Hazra, Narayanaswamy Balakrishnan

Sequential order statistics (SOS) are useful tools for modeling the lifetimes of systems wherein the failure of a component has a significant impact on the lifetimes of the remaining surviving components. The SOS model is a general model that contains most of the existing models for ordered random variables. In this paper, we consider the SOS model with non-identical components and then discuss various univariate and multivariate stochastic comparison results in both one-and two-sample scenarios.

序列有序统计(SOS)是建立系统寿命模型的有用工具,其中一个组件的失效会对其余存活组件的寿命产生重大影响。SOS 模型是一个通用模型,包含了大多数现有的有序随机变量模型。在本文中,我们考虑了具有非相同组件的 SOS 模型,然后讨论了单样本和双样本情况下的各种单变量和多变量随机比较结果。
{"title":"Multivariate stochastic comparisons of sequential order statistics with non-identical components","authors":"Tanmay Sahoo, Nil Kamal Hazra, Narayanaswamy Balakrishnan","doi":"10.1007/s00362-024-01558-w","DOIUrl":"https://doi.org/10.1007/s00362-024-01558-w","url":null,"abstract":"<p>Sequential order statistics (SOS) are useful tools for modeling the lifetimes of systems wherein the failure of a component has a significant impact on the lifetimes of the remaining surviving components. The SOS model is a general model that contains most of the existing models for ordered random variables. In this paper, we consider the SOS model with non-identical components and then discuss various univariate and multivariate stochastic comparison results in both one-and two-sample scenarios.</p>","PeriodicalId":51166,"journal":{"name":"Statistical Papers","volume":"128 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140883338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New copula families and mixing properties 新的共轭系和混合特性
IF 1.3 3区 数学 Q2 STATISTICS & PROBABILITY Pub Date : 2024-05-06 DOI: 10.1007/s00362-024-01559-9
Martial Longla

We characterize absolutely continuous symmetric copulas with square integrable densities in this paper. This characterization is used to create new copula families, that are perturbations of the independence copula. The full study of mixing properties of Markov chains generated by these copula families is conducted. An extension that includes the Farlie–Gumbel–Morgenstern family of copulas is proposed. We propose some examples of copulas that generate non-mixing Markov chains, but whose convex combinations generate (psi )-mixing Markov chains. Some general results on (psi )-mixing are given. The Spearman’s correlation (rho _S) and Kendall’s (tau ) are provided for the created copula families. Some general remarks are provided for (rho _S) and (tau ). A central limit theorem is provided for parameter estimators in one example. A simulation study is conducted to support derived asymptotic distributions for some examples.

我们在本文中描述了具有平方可积分密度的绝对连续对称 copula 的特征。我们利用这一特征创建了新的共轭族,它们是独立性共轭的扰动。本文全面研究了由这些共轭族生成的马尔可夫链的混合特性。我们提出了包括 Farlie-Gumbel-Morgenstern 共轭系的扩展。我们提出了一些产生非混合马尔科夫链的共线性的例子,但它们的凸组合产生了(psi )混合马尔科夫链。给出了一些关于混杂的一般结果。为所创建的 copula 系列提供了 Spearman 相关性和 Kendall 相关性。为 (rho _S) 和 (tau ) 提供了一些一般性说明。在一个例子中为参数估计值提供了中心极限定理。对一些例子进行了模拟研究,以支持推导出的渐近分布。
{"title":"New copula families and mixing properties","authors":"Martial Longla","doi":"10.1007/s00362-024-01559-9","DOIUrl":"https://doi.org/10.1007/s00362-024-01559-9","url":null,"abstract":"<p>We characterize absolutely continuous symmetric copulas with square integrable densities in this paper. This characterization is used to create new copula families, that are perturbations of the independence copula. The full study of mixing properties of Markov chains generated by these copula families is conducted. An extension that includes the Farlie–Gumbel–Morgenstern family of copulas is proposed. We propose some examples of copulas that generate non-mixing Markov chains, but whose convex combinations generate <span>(psi )</span>-mixing Markov chains. Some general results on <span>(psi )</span>-mixing are given. The Spearman’s correlation <span>(rho _S)</span> and Kendall’s <span>(tau )</span> are provided for the created copula families. Some general remarks are provided for <span>(rho _S)</span> and <span>(tau )</span>. A central limit theorem is provided for parameter estimators in one example. A simulation study is conducted to support derived asymptotic distributions for some examples.</p>","PeriodicalId":51166,"journal":{"name":"Statistical Papers","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140883228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple random change points in survival analysis with applications to clinical trials 生存分析中的多个随机变化点在临床试验中的应用
IF 1.3 3区 数学 Q2 STATISTICS & PROBABILITY Pub Date : 2024-05-06 DOI: 10.1007/s00362-023-01507-z
Jianbo Xu

There is often a presence of random change points (RCPs) with varying timing of hazard rate change among patients in survival analysis within oncology trials. This is in contrast to fixed change points in piecewise constant hazard models, where the timing of hazard rate change remains the same for all subjects. However, currently there is a lack of appropriate statistical methods to effectively tackle this particular issue. This article presents novel statistical methods that aim to characterize these complex survival models. These methods allow for the estimation of important features such as the probability of an event occurring and being censored, and the expected number of events within the clinical trial, prior to any specific time, and within specific time intervals. They also derive expected survival time and parametric expected survival and hazard functions for subjects with any finite number of RCPs. Simulation studies validate these methods and demonstrate their reliability and effectiveness. Real clinical data from an oncology trial is also used to apply these methods. The applications of these methods in oncology trials are extensive, including estimating hazard rates and rate parameters of RCPs, assessing treatment switching, delayed onset of immunotherapy, and subsequent anticancer therapies. They also have value in clinical trial planning, monitoring, and sample size adjustment. The expected parametric survival and hazard functions provide a thorough understanding of the behaviors and effects of RCPs in complex survival models.

在肿瘤试验的生存分析中,经常会出现随机变化点(RCPs),不同患者的危险率变化时间各不相同。这与片断恒定危险模型中的固定变化点形成鲜明对比,在固定变化点中,所有受试者的危险率变化时间保持不变。然而,目前缺乏适当的统计方法来有效解决这一特殊问题。本文介绍了旨在描述这些复杂生存模型特征的新型统计方法。这些方法可估算重要特征,如事件发生和被删减的概率,以及临床试验中、任何特定时间之前和特定时间间隔内的预期事件数量。他们还推导出了具有任意有限数量 RCP 的受试者的预期生存时间以及参数预期生存和危险函数。模拟研究验证了这些方法,并证明了它们的可靠性和有效性。来自肿瘤试验的真实临床数据也被用来应用这些方法。这些方法在肿瘤试验中的应用非常广泛,包括估计 RCP 的危险率和速率参数、评估治疗转换、免疫疗法的延迟开始以及后续抗癌疗法。它们在临床试验规划、监测和样本量调整方面也有价值。预期参数生存和危险函数让我们对复杂生存模型中 RCP 的行为和影响有了透彻的了解。
{"title":"Multiple random change points in survival analysis with applications to clinical trials","authors":"Jianbo Xu","doi":"10.1007/s00362-023-01507-z","DOIUrl":"https://doi.org/10.1007/s00362-023-01507-z","url":null,"abstract":"<p>There is often a presence of random change points (RCPs) with varying timing of hazard rate change among patients in survival analysis within oncology trials. This is in contrast to fixed change points in piecewise constant hazard models, where the timing of hazard rate change remains the same for all subjects. However, currently there is a lack of appropriate statistical methods to effectively tackle this particular issue. This article presents novel statistical methods that aim to characterize these complex survival models. These methods allow for the estimation of important features such as the probability of an event occurring and being censored, and the expected number of events within the clinical trial, prior to any specific time, and within specific time intervals. They also derive expected survival time and parametric expected survival and hazard functions for subjects with any finite number of RCPs. Simulation studies validate these methods and demonstrate their reliability and effectiveness. Real clinical data from an oncology trial is also used to apply these methods. The applications of these methods in oncology trials are extensive, including estimating hazard rates and rate parameters of RCPs, assessing treatment switching, delayed onset of immunotherapy, and subsequent anticancer therapies. They also have value in clinical trial planning, monitoring, and sample size adjustment. The expected parametric survival and hazard functions provide a thorough understanding of the behaviors and effects of RCPs in complex survival models.</p>","PeriodicalId":51166,"journal":{"name":"Statistical Papers","volume":"26 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140883339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nested symmetrical Latin hypercube designs 嵌套对称拉丁超立方设计
IF 1.3 3区 数学 Q2 STATISTICS & PROBABILITY Pub Date : 2024-05-06 DOI: 10.1007/s00362-024-01556-y
Xiaodi Wang, Hengzhen Huang

Symmetrical global sensitivity analysis (SGSA) can aid practitioners in reducing the model complexity by identifying symmetries within the model. In this paper, we propose a nested symmetrical Latin hypercube design (NSLHD) for implementing SGSA in a sequential manner. By combining the strengths of the nested Latin hypercube design and symmetrical design, the proposed design allows for the implementation of SGSA without the need to pre-determine the sample size of the experiment. We develop a random sampling procedure and an efficient sequential optimization algorithm to construct flexible NSLHDs in terms of runs and factors. Sampling properties of the constructed designs are studied. Numerical examples are given to demonstrate the effectiveness of the NSLHD for designing sequential sensitivity analysis.

对称全局敏感性分析(SGSA)可以通过识别模型内部的对称性来帮助从业人员降低模型的复杂性。在本文中,我们提出了一种嵌套对称拉丁超立方设计(NSLHD),用于以顺序方式实施 SGSA。通过结合嵌套拉丁超立方设计和对称设计的优势,所提出的设计可以在无需预先确定实验样本大小的情况下实施 SGSA。我们开发了一种随机抽样程序和一种高效的序列优化算法,以在运行和因子方面构建灵活的 NSLHD。我们研究了所构建设计的抽样特性。我们给出了数值示例,以证明 NSLHD 在设计顺序敏感性分析方面的有效性。
{"title":"Nested symmetrical Latin hypercube designs","authors":"Xiaodi Wang, Hengzhen Huang","doi":"10.1007/s00362-024-01556-y","DOIUrl":"https://doi.org/10.1007/s00362-024-01556-y","url":null,"abstract":"<p>Symmetrical global sensitivity analysis (SGSA) can aid practitioners in reducing the model complexity by identifying symmetries within the model. In this paper, we propose a nested symmetrical Latin hypercube design (NSLHD) for implementing SGSA in a sequential manner. By combining the strengths of the nested Latin hypercube design and symmetrical design, the proposed design allows for the implementation of SGSA without the need to pre-determine the sample size of the experiment. We develop a random sampling procedure and an efficient sequential optimization algorithm to construct flexible NSLHDs in terms of runs and factors. Sampling properties of the constructed designs are studied. Numerical examples are given to demonstrate the effectiveness of the NSLHD for designing sequential sensitivity analysis.</p>","PeriodicalId":51166,"journal":{"name":"Statistical Papers","volume":"112 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140883227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A two sample nonparametric test for variability via empirical likelihood methods 通过经验似然法对变异性进行双样本非参数检验
IF 1.3 3区 数学 Q2 STATISTICS & PROBABILITY Pub Date : 2024-05-02 DOI: 10.1007/s00362-024-01555-z
Lisa Parveen, Ruhul Ali Khan, Murari Mitra

Comparison of variability or dispersion of two distributions is the major focus of this work. To this end, we consider a two sample testing problem for detecting dominance in dispersive order and develop a test based on U-statistic approach. We also explore a link between the two measures of variability, viz. dispersive order and Gini’s mean difference (GMD). We exploit methodologies based on jackknife empirical likelihood (JEL) and adjusted JEL in order to overcome certain practical difficulties. The performance of the proposed test is assessed by means of a simulation study. Finally, we apply our test in the context of several real life situations including medical studies and insurance data.

比较两个分布的变异性或分散性是这项工作的重点。为此,我们考虑了一个检测分散秩支配性的双样本检验问题,并开发了一种基于 U 统计的检验方法。我们还探讨了两种可变性测量之间的联系,即分散秩序和基尼均值差(GMD)。为了克服某些实际困难,我们利用了基于杰克刀经验似然法(JEL)和调整 JEL 的方法。我们通过模拟研究来评估所提出的检验方法的性能。最后,我们将我们的检验方法应用于包括医学研究和保险数据在内的几种实际情况中。
{"title":"A two sample nonparametric test for variability via empirical likelihood methods","authors":"Lisa Parveen, Ruhul Ali Khan, Murari Mitra","doi":"10.1007/s00362-024-01555-z","DOIUrl":"https://doi.org/10.1007/s00362-024-01555-z","url":null,"abstract":"<p>Comparison of variability or dispersion of two distributions is the major focus of this work. To this end, we consider a two sample testing problem for detecting dominance in dispersive order and develop a test based on <i>U</i>-statistic approach. We also explore a link between the two measures of variability, viz. dispersive order and Gini’s mean difference (GMD). We exploit methodologies based on jackknife empirical likelihood (JEL) and adjusted JEL in order to overcome certain practical difficulties. The performance of the proposed test is assessed by means of a simulation study. Finally, we apply our test in the context of several real life situations including medical studies and insurance data.\u0000</p>","PeriodicalId":51166,"journal":{"name":"Statistical Papers","volume":"194 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140883340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Statistical Papers
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1