Pub Date : 2021-03-17DOI: 10.17533/UDEA.VITAE.V28N1A341703
German Madrigal Redondo, Daniela González Corrales, Marianela Chavarría Rojas, Tatiana Monge Quiros, Wendy Cruz Sibaja, Norman Rojas Campos
Background: Periodontal disease is the infection and inflammation of the gums, bones, and tissues involved in teeth support, and it is one of the most common diseases affecting pet dogs. Essential oils have shown antimicrobial activity against bacteria causing periodontal disease; therefore, they are considered potential therapeutic agents. Objectives: The main objective was to formulate and evaluate the antimicrobial activity of a 0.2% chlorhexidine canine mouthwash with essential oils. Methods: Three microemulsion formulations were obtained by constructing a pseudo-ternary phase diagram using the phase titration method. Different surfactant agents were evaluated, and hydrogenated castor oil was selected as the emulsifier agent. The antimicrobial activity of oregano essential oil (Origanum vulgare), thyme essential oil (Thymus vulgaris), and the three formulations were evaluated against Staphylococcus aureus, Streptococcus mutans, Streptococcus salivarius, and Escherichia coli. Results: Pure thyme and oregano essential oils showed higher antimicrobial activity than a 0,2% chlorhexidine solution. The formulations with essential oils plus chlorhexidine and chlorhexidine alone showed antimicrobial activity. The formulation containing only essential oils did not show antimicrobial activity. Conclusions: A canine mouthwash was formulated with chlorhexidine and thyme and oregano essential oil. Based on the evaluation of antimicrobial activity, two of the proposed formulations could be a therapeutic option to reduce the risk and prevent periodontal disease in canines.
{"title":"Formulation and antimicrobial activity evaluation of a 0.2% chlorhexidine canine mouthwash with essential oils","authors":"German Madrigal Redondo, Daniela González Corrales, Marianela Chavarría Rojas, Tatiana Monge Quiros, Wendy Cruz Sibaja, Norman Rojas Campos","doi":"10.17533/UDEA.VITAE.V28N1A341703","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V28N1A341703","url":null,"abstract":"Background: Periodontal disease is the infection and inflammation of the gums, bones, and tissues involved in teeth support, and it is one of the most common diseases affecting pet dogs. Essential oils have shown antimicrobial activity against bacteria causing periodontal disease; therefore, they are considered potential therapeutic agents. Objectives: The main objective was to formulate and evaluate the antimicrobial activity of a 0.2% chlorhexidine canine mouthwash with essential oils. Methods: Three microemulsion formulations were obtained by constructing a pseudo-ternary phase diagram using the phase titration method. Different surfactant agents were evaluated, and hydrogenated castor oil was selected as the emulsifier agent. The antimicrobial activity of oregano essential oil (Origanum vulgare), thyme essential oil (Thymus vulgaris), and the three formulations were evaluated against Staphylococcus aureus, Streptococcus mutans, Streptococcus salivarius, and Escherichia coli. Results: Pure thyme and oregano essential oils showed higher antimicrobial activity than a 0,2% chlorhexidine solution. The formulations with essential oils plus chlorhexidine and chlorhexidine alone showed antimicrobial activity. The formulation containing only essential oils did not show antimicrobial activity. Conclusions: A canine mouthwash was formulated with chlorhexidine and thyme and oregano essential oil. Based on the evaluation of antimicrobial activity, two of the proposed formulations could be a therapeutic option to reduce the risk and prevent periodontal disease in canines.","PeriodicalId":51213,"journal":{"name":"Vitae","volume":"140 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88744962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-25DOI: 10.17533/UDEA.VITAE.V28N1A342472
C. Marín-Tello, Haydée Villafana-Medina, J. Aliaga-Arauco, Violeta Malpartida-Tello, E. Castañeda-Marín, C. Sánchez-Marín, J. Vasquez-Kool
Background: Oxidative stress, genetic expression changes, and decomposition of the blood-brain barrier have been shown to be caused by exposure to radiofrequency radiation (RFR); therefore, the search for drugs or food products that offer some protection from these effects has attracted interest. Lepidium meyenii (maca) is a native Andean plant known for its effects on the female reproductive system as well as its immunomodulating, energizing, antioxidant, and nutritive properties due to its high concentration of alkaloids, amino acids, glucosinolates, fatty acids, and macamides. Objectives: We aim to determine the effect of dietary maca supplementation on spatial memory and cerebral oxidative damage in rats with induced menopause and/or with exposure to mobile phone radiation. Method: Female rats divided into 6 groups (six rats in each group): control or not ovariectomized (O-), ovariectomized (O+), ovariectomized + estrogen (O+E+), ovariectomized + estrogen + irradiated (O+E+I+), ovariectomized + maca (O+M+), and ovariectomized + maca + irradiated (O+M+I). Rat spatial memory was tested using the Morris water navigation task. Rats were sacrificed, and cerebral malondialdehyde was measured. Results: After exposure to mobile phone radiation, the group supplemented with maca showed improved spatial memory and lower levels of malondialdehyde than the estrogenized group. Conclusions: Our results suggest that consumption of maca has a positive effect on the maintenance of memory and decreases oxidative stress caused by mobile phone radiation. However, it is necessary to extend this work using a larger sample size.
{"title":"Effect of Lepidium meyenii (maca) on spatial memory and brain oxidative damage of ovariectomized-rats exposed to mobile phone","authors":"C. Marín-Tello, Haydée Villafana-Medina, J. Aliaga-Arauco, Violeta Malpartida-Tello, E. Castañeda-Marín, C. Sánchez-Marín, J. Vasquez-Kool","doi":"10.17533/UDEA.VITAE.V28N1A342472","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V28N1A342472","url":null,"abstract":"Background: Oxidative stress, genetic expression changes, and decomposition of the blood-brain barrier have been shown to be caused by exposure to radiofrequency radiation (RFR); therefore, the search for drugs or food products that offer some protection from these effects has attracted interest. Lepidium meyenii (maca) is a native Andean plant known for its effects on the female reproductive system as well as its immunomodulating, energizing, antioxidant, and nutritive properties due to its high concentration of alkaloids, amino acids, glucosinolates, fatty acids, and macamides. Objectives: We aim to determine the effect of dietary maca supplementation on spatial memory and cerebral oxidative damage in rats with induced menopause and/or with exposure to mobile phone radiation. Method: Female rats divided into 6 groups (six rats in each group): control or not ovariectomized (O-), ovariectomized (O+), ovariectomized + estrogen (O+E+), ovariectomized + estrogen + irradiated (O+E+I+), ovariectomized + maca (O+M+), and ovariectomized + maca + irradiated (O+M+I). Rat spatial memory was tested using the Morris water navigation task. Rats were sacrificed, and cerebral malondialdehyde was measured. Results: After exposure to mobile phone radiation, the group supplemented with maca showed improved spatial memory and lower levels of malondialdehyde than the estrogenized group. Conclusions: Our results suggest that consumption of maca has a positive effect on the maintenance of memory and decreases oxidative stress caused by mobile phone radiation. However, it is necessary to extend this work using a larger sample size.","PeriodicalId":51213,"journal":{"name":"Vitae","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90575293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Globally, the need to address strategies for preventing infections associated with health care has increased worldwide. In the city of Valledupar, Colombia, reports of bacteria resistant to chemical or enzymatic biocides in hospital environments and surfaces are increasingly frequent, evidencing the importance of conducting studies aimed at identifying alternative active ingredients for disinfectant products. Objective: Evaluate the in vitro effectiveness of Neem leaves extract over bacteria strains isolated from different areas and surfaces of a health institution in Valledupar, compared to disinfectants for hospital use, an enzymatic detergent, and a commercial chemical disinfectant. Methods: Biocidal activities on bacteria isolated from hospital surfaces, such as Acinetobacter baumanni, Bacillus subtilis, Enterobacter aerogenes, Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus sp, and Stenotrophomonas malthophila were analyzed. The Neem leaves extract was evaluated at concentrations of 3, 4, and 5 % for each bacterium during 15-minute contact time, incubated at 37 °C for 18 hours. We compared two antimicrobial chemicals, a disinfectant (based on formaldehyde, cetrimide, and glutaraldehyde), and an enzymatic detergent (based on protease, lipase, and amylase). Results: The aqueous Neem extract did not show significant differences with the other treatments with 99.48 to 100% inhibition against bacteria of the species Acinetobacter baumanni, Enterobacter aerogenes, Staphylococcus aureus, and Micrococcus sp.; Bacillus subtilis, and Stenotrophomonas maltophilia strains were the most resistant strains inhibited by enzymatic detergent and disinfectant, respectively. None of the products evaluated were effective against all in vitrostrains. Conclusions: These data show Neem’s bacteriostatic properties, its potential in in-hospital products, and the need to combine different active ingredients in a disinfection plan.
{"title":"In vitro effectiveness of an aqueous extract of Neem (Azadirachta indica A. Juss) leaves on bacteria causing healthcare associated infection in Valledupar","authors":"Aslenis Emidia Melo Rios, Hedilka Jimenez Rios, Bertilda Pedraza Claros, Jeraldin Castrillon Mejia, Ailyn Fuentes Arias","doi":"10.17533/UDEA.VITAE.V27N3A05","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V27N3A05","url":null,"abstract":"Background: Globally, the need to address strategies for preventing infections associated with health care has increased worldwide. In the city of Valledupar, Colombia, reports of bacteria resistant to chemical or enzymatic biocides in hospital environments and surfaces are increasingly frequent, evidencing the importance of conducting studies aimed at identifying alternative active ingredients for disinfectant products. Objective: Evaluate the in vitro effectiveness of Neem leaves extract over bacteria strains isolated from different areas and surfaces of a health institution in Valledupar, compared to disinfectants for hospital use, an enzymatic detergent, and a commercial chemical disinfectant. Methods: Biocidal activities on bacteria isolated from hospital surfaces, such as Acinetobacter baumanni, Bacillus subtilis, Enterobacter aerogenes, Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus sp, and Stenotrophomonas malthophila were analyzed. The Neem leaves extract was evaluated at concentrations of 3, 4, and 5 % for each bacterium during 15-minute contact time, incubated at 37 °C for 18 hours. We compared two antimicrobial chemicals, a disinfectant (based on formaldehyde, cetrimide, and glutaraldehyde), and an enzymatic detergent (based on protease, lipase, and amylase). Results: The aqueous Neem extract did not show significant differences with the other treatments with 99.48 to 100% inhibition against bacteria of the species Acinetobacter baumanni, Enterobacter aerogenes, Staphylococcus aureus, and Micrococcus sp.; Bacillus subtilis, and Stenotrophomonas maltophilia strains were the most resistant strains inhibited by enzymatic detergent and disinfectant, respectively. None of the products evaluated were effective against all in vitrostrains. Conclusions: These data show Neem’s bacteriostatic properties, its potential in in-hospital products, and the need to combine different active ingredients in a disinfection plan.","PeriodicalId":51213,"journal":{"name":"Vitae","volume":"158 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86946656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-14DOI: 10.17533/UDEA.VITAE.V27N3A04
Gerardo Alberto Castaño Riobueno, Monica Garcia Baquero, Yhoinson Aranda Moreno
Background: Self-medication is a social practice that is becoming increasingly common in Colombia due to difficulties in healthcare access, long waits for appointments, or not enough time for users to visit their doctors or make checkup appointments. The aforementioned is reflected by the requests, claims and complaints received by the Superintendent of Health in Colombia during 2018, reaching near one million, 12% of which were due to the untimely availability of specialized medical appointments, and 6% are due to the untimely and delivery of medications. The untimely delivery of medications can lead to consequences such as self-medication along with its side effects, adverse reactions, occasional intoxications, and ineffectiveness due to their use in situations for which they are not indicated. For these reasons, this study explores cases among students from the Faculty of Health Sciences at the Universidad de Los Llanos. Methodology: A descriptive cross-sectional study was conducted, and the information was gathered by surveying a group of 270 students. Sampling was done on a pro-rata basis, accounting for the number of students per semester, and study degree. This instrument was approved by health professionals who held masters-level educations. The survey included variables such as demographic data, health status, knowledge of medications, and self-medication culture. Results: From the results obtained, 91% of the students are between ages 15 and 24, and 67% admitted self-medicated or used medications for ailments such as flu (67%), headache (60%), and fever (40%). The most used drugs included acetaminophen 90.1%, ibuprofen 49.7%, and 53.6% natural products, especially herbal infusions. Students stated they self-medicated because they did not have enough time to visit the doctor (42.5%). Conclusion: This study found that students understood the concept of self-medication and still used medications without a prescription, and 39.6% (107/270) of the students self-medicated at least once a month.
{"title":"Factors that predispose self-medication in university students, a colombian case","authors":"Gerardo Alberto Castaño Riobueno, Monica Garcia Baquero, Yhoinson Aranda Moreno","doi":"10.17533/UDEA.VITAE.V27N3A04","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V27N3A04","url":null,"abstract":"Background: Self-medication is a social practice that is becoming increasingly common in Colombia due to difficulties in healthcare access, long waits for appointments, or not enough time for users to visit their doctors or make checkup appointments. The aforementioned is reflected by the requests, claims and complaints received by the Superintendent of Health in Colombia during 2018, reaching near one million, 12% of which were due to the untimely availability of specialized medical appointments, and 6% are due to the untimely and delivery of medications. The untimely delivery of medications can lead to consequences such as self-medication along with its side effects, adverse reactions, occasional intoxications, and ineffectiveness due to their use in situations for which they are not indicated. For these reasons, this study explores cases among students from the Faculty of Health Sciences at the Universidad de Los Llanos. Methodology: A descriptive cross-sectional study was conducted, and the information was gathered by surveying a group of 270 students. Sampling was done on a pro-rata basis, accounting for the number of students per semester, and study degree. This instrument was approved by health professionals who held masters-level educations. The survey included variables such as demographic data, health status, knowledge of medications, and self-medication culture. Results: From the results obtained, 91% of the students are between ages 15 and 24, and 67% admitted self-medicated or used medications for ailments such as flu (67%), headache (60%), and fever (40%). The most used drugs included acetaminophen 90.1%, ibuprofen 49.7%, and 53.6% natural products, especially herbal infusions. Students stated they self-medicated because they did not have enough time to visit the doctor (42.5%). Conclusion: This study found that students understood the concept of self-medication and still used medications without a prescription, and 39.6% (107/270) of the students self-medicated at least once a month.","PeriodicalId":51213,"journal":{"name":"Vitae","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79163319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-18DOI: 10.17533/UDEA.VITAE.V27N3A03
Melany Villegas-Valencia, Libardo Andrés González-Reyes, Helberg Asencio-Santofimio, José Óscar Gutiérrez-Montes, A. Garcia, Silverio Garzón-Gaviria
BACKGROUND: Colombia has a high diversity of medicinal plants, including Tachuelo (Zanthoxylum rhoifolium), a tree belonging to the family Rutaceae, which has been attributed an analgesic use by communities of the Colombian southwest. Nevertheless, this species has been scarce studied in Colombia. The studies have been limited to the isolation of compounds with antifungal and insecticide activity, using the leaves, branches, and bark of the plant in aqueous, and organic extracts. Neither pharmacological tests have been carried out, nor the analgesic and neuromotor activity have been tested from preparations with this plant’s fruits. OBJECTIVES: To evaluate the analgesic and neuromotor effect of the aqueous and hexane extract of the fruits of Z. rhoifolium. METHODS: As there were no preliminary reports of this study, the first observation was made through Irwin’s test. The formalin and the rotarod test were performed to determine the analgesic and motor coordination effects, respectively. RESULTS: All the evaluated treatments demonstrated to generate analgesia, anesthesia, passivity, reduction in the alarm reaction, and have antinociceptive activity in the formalin test; while only the high dose of the nonpolar extract generated a deficit in the motor performance of the rodents in the rotarod test. CONCLUSIONS: the antinociceptive effect of the aqueous and hexane extracts of this species’ fruits was demonstrated. The hexane extract generated a neuromotor effect, which validates the ethnobotanical reports on Z. rhoifolium fruits.
{"title":"Analgesic and neuromotor effects of two extracts of Zanthoxylum rhoifolium (Rutaceae) in the Swiss albino mouse (Mus musculus)","authors":"Melany Villegas-Valencia, Libardo Andrés González-Reyes, Helberg Asencio-Santofimio, José Óscar Gutiérrez-Montes, A. Garcia, Silverio Garzón-Gaviria","doi":"10.17533/UDEA.VITAE.V27N3A03","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V27N3A03","url":null,"abstract":"BACKGROUND: Colombia has a high diversity of medicinal plants, including Tachuelo (Zanthoxylum rhoifolium), a tree belonging to the family Rutaceae, which has been attributed an analgesic use by communities of the Colombian southwest. Nevertheless, this species has been scarce studied in Colombia. The studies have been limited to the isolation of compounds with antifungal and insecticide activity, using the leaves, branches, and bark of the plant in aqueous, and organic extracts. Neither pharmacological tests have been carried out, nor the analgesic and neuromotor activity have been tested from preparations with this plant’s fruits. OBJECTIVES: To evaluate the analgesic and neuromotor effect of the aqueous and hexane extract of the fruits of Z. rhoifolium. METHODS: As there were no preliminary reports of this study, the first observation was made through Irwin’s test. The formalin and the rotarod test were performed to determine the analgesic and motor coordination effects, respectively. RESULTS: All the evaluated treatments demonstrated to generate analgesia, anesthesia, passivity, reduction in the alarm reaction, and have antinociceptive activity in the formalin test; while only the high dose of the nonpolar extract generated a deficit in the motor performance of the rodents in the rotarod test. CONCLUSIONS: the antinociceptive effect of the aqueous and hexane extracts of this species’ fruits was demonstrated. The hexane extract generated a neuromotor effect, which validates the ethnobotanical reports on Z. rhoifolium fruits.","PeriodicalId":51213,"journal":{"name":"Vitae","volume":"62 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86393511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-11DOI: 10.17533/udea.vitae.v27n3a02
Marcela Forgerini, Geovana Schiavo, R. Lucchetta, P. Mastroianni
Background: The elderly people have high morbimortality associated with respiratory disorders, in addition to the presence of other safety risk factors, such as the use of potentially inappropriate medication and the occurrence of drug interactions. Objective: Considering the current pandemic scenario, it was intended to identify explicit criteria-based tools that reported drug interactions between potentially inappropriate medication and respiratory system disorders and possibly worse prognosis of COVID-19 infection. Methods: A systematic scoping review was conducted until February 2020. Study characteristics of explicit criteria-based tools, and potentially inappropriate medication, drug interactions, and therapeutic management, were extracted. Results: Nineteen explicit criteria-based tools were included. Nineteen drug interactions and 17 potentially inappropriate medications with concerns for three respiratory disorders (asthma, chronic pulmonary obstructive disease, and respiratory failure) were identified. The most frequent pharmacological classes reported were benzodiazepines and beta-blockers. For clinical management, the tools recommend using cardioselective beta-blockers, calcium channel blockers, angiotensin-converting enzyme inhibitors, and angiotensin II type I receptor blockers, and benzodiazepines with a short or intermediate half-life. Conclusion: Considering the increased risk of COVID-19 infection in the elderly, drug interactions and the use of potentially inappropriate medication associated with the occurrence of adverse drug events in the respiratory system may also worsening COVID-19 infection in patients with uncontrolled respiratory disorders. Thus, it is essential to assess drug therapy in use, to identify safety risks, and monitor the elderly in general and those with a worse prognosis concerning COVID-19, promoting patient safety.
{"title":"Drug interactions for elderly with respiratory disorders and times of COVID-19: a systematic scoping review","authors":"Marcela Forgerini, Geovana Schiavo, R. Lucchetta, P. Mastroianni","doi":"10.17533/udea.vitae.v27n3a02","DOIUrl":"https://doi.org/10.17533/udea.vitae.v27n3a02","url":null,"abstract":"Background: The elderly people have high morbimortality associated with respiratory disorders, in addition to the presence of other safety risk factors, such as the use of potentially inappropriate medication and the occurrence of drug interactions. Objective: Considering the current pandemic scenario, it was intended to identify explicit criteria-based tools that reported drug interactions between potentially inappropriate medication and respiratory system disorders and possibly worse prognosis of COVID-19 infection. Methods: A systematic scoping review was conducted until February 2020. Study characteristics of explicit criteria-based tools, and potentially inappropriate medication, drug interactions, and therapeutic management, were extracted. Results: Nineteen explicit criteria-based tools were included. Nineteen drug interactions and 17 potentially inappropriate medications with concerns for three respiratory disorders (asthma, chronic pulmonary obstructive disease, and respiratory failure) were identified. The most frequent pharmacological classes reported were benzodiazepines and beta-blockers. For clinical management, the tools recommend using cardioselective beta-blockers, calcium channel blockers, angiotensin-converting enzyme inhibitors, and angiotensin II type I receptor blockers, and benzodiazepines with a short or intermediate half-life. Conclusion: Considering the increased risk of COVID-19 infection in the elderly, drug interactions and the use of potentially inappropriate medication associated with the occurrence of adverse drug events in the respiratory system may also worsening COVID-19 infection in patients with uncontrolled respiratory disorders. Thus, it is essential to assess drug therapy in use, to identify safety risks, and monitor the elderly in general and those with a worse prognosis concerning COVID-19, promoting patient safety.","PeriodicalId":51213,"journal":{"name":"Vitae","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91249723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-11DOI: 10.17533/udea.vitae.v27n3a01
R. Ordoñez-Araque, Johnny RODRÍGUEZ-VILLACRES, Julio C. Urresto-Villegas
Background: The electronic nose, tongue, and eye are futuristic technologies that have been used for many years; they have been gaining market in different types of industries and can increasingly be found in the food area; their function is to determine sensory characteristics (smell, aroma, and flavor) and objective visuals, without the subjectivity that can be represented by sensory analysis by people (the study that can complement the analysis of machines, without being exclusive). Objectives: Find the main generalities of these mechanisms, their sensors, software, mechanism of action, and applications within the food industry. Methods: A search was carried out in the main databases of indexed articles, with terms that allowed collecting the necessary information, and 89 articles were used that met different inclusion criteria. Results: The main outcomes were to understand the operation of each of these technologies, what their main components are, and how they can be linked in the beer, wine, oil, fruit, vegetable, dairy, etc. industry to determine their quality, safety, and fraud. Conclusions: The use of electronic nose, tongue, and eye is found in more food industries every day. Its technology continues to evolve; the future of sensory analysis will undoubtedly apply these mechanisms due to the reliability, speed, and reproducibility of the results.
{"title":"Electronic Nose, Tongue and Eye: Their Usefulness for the Food Industry","authors":"R. Ordoñez-Araque, Johnny RODRÍGUEZ-VILLACRES, Julio C. Urresto-Villegas","doi":"10.17533/udea.vitae.v27n3a01","DOIUrl":"https://doi.org/10.17533/udea.vitae.v27n3a01","url":null,"abstract":"Background: The electronic nose, tongue, and eye are futuristic technologies that have been used for many years; they have been gaining market in different types of industries and can increasingly be found in the food area; their function is to determine sensory characteristics (smell, aroma, and flavor) and objective visuals, without the subjectivity that can be represented by sensory analysis by people (the study that can complement the analysis of machines, without being exclusive). Objectives: Find the main generalities of these mechanisms, their sensors, software, mechanism of action, and applications within the food industry. Methods: A search was carried out in the main databases of indexed articles, with terms that allowed collecting the necessary information, and 89 articles were used that met different inclusion criteria. Results: The main outcomes were to understand the operation of each of these technologies, what their main components are, and how they can be linked in the beer, wine, oil, fruit, vegetable, dairy, etc. industry to determine their quality, safety, and fraud. Conclusions: The use of electronic nose, tongue, and eye is found in more food industries every day. Its technology continues to evolve; the future of sensory analysis will undoubtedly apply these mechanisms due to the reliability, speed, and reproducibility of the results.","PeriodicalId":51213,"journal":{"name":"Vitae","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78206360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-10DOI: 10.17533/udea.vitae.v27n1a03
M. Zapata, A. Polo, A. Alzate, Luis Fernando Restrepo Betancur, B. Rojano, M. Maldonado
Background: Mango (Mangifera indica L.) is one of the world’s most consumed fruit, and it is also a rich source of antioxidants that may prevent oxidative stress. Objectives: This study aimed to determine if mango (cv. Azúcar) juice can improve the antioxidant status of healthy individuals with low consumption of vegetables and fruit. Methods: This was a cross-over single-blind study carried out with 16 healthy individuals for 73 days. Participants were randomly assigned to either a mango juice period or a placebo period. Total phenolic content, antioxidant capacity, mangiferin, thiobarbituric acid reactive substances (TBARS), total glutathione, and 8-hydroxydeoxyguanosine levels were determined in plasma. Results: Plasma antioxidant activity was significantly higher in the juice consumption period than the placebo consumption period; however, total phenolic content, total glutathione, TBARS, and 8-hydroxydeoxyguanosine levels did not show significant differences between juice period and placebo period. Mangiferin was detected in every participant after juice consumption. Conclusions: Mango (cv. Azúcar) juice daily consumption improves plasma antioxidant capacity.
{"title":"EFFECT OF MANGO (Mangifera indica) CV. AZÚCAR JUICE CONSUMPTION ON PLASMA ANTIOXIDANT CAPACITY AND OXIDATIVE STRESS BIOMARKERS","authors":"M. Zapata, A. Polo, A. Alzate, Luis Fernando Restrepo Betancur, B. Rojano, M. Maldonado","doi":"10.17533/udea.vitae.v27n1a03","DOIUrl":"https://doi.org/10.17533/udea.vitae.v27n1a03","url":null,"abstract":"Background: Mango (Mangifera indica L.) is one of the world’s most consumed fruit, and it is also a rich source of antioxidants that may prevent oxidative stress. Objectives: This study aimed to determine if mango (cv. Azúcar) juice can improve the antioxidant status of healthy individuals with low consumption of vegetables and fruit. Methods: This was a cross-over single-blind study carried out with 16 healthy individuals for 73 days. Participants were randomly assigned to either a mango juice period or a placebo period. Total phenolic content, antioxidant capacity, mangiferin, thiobarbituric acid reactive substances (TBARS), total glutathione, and 8-hydroxydeoxyguanosine levels were determined in plasma. Results: Plasma antioxidant activity was significantly higher in the juice consumption period than the placebo consumption period; however, total phenolic content, total glutathione, TBARS, and 8-hydroxydeoxyguanosine levels did not show significant differences between juice period and placebo period. Mangiferin was detected in every participant after juice consumption. Conclusions: Mango (cv. Azúcar) juice daily consumption improves plasma antioxidant capacity.","PeriodicalId":51213,"journal":{"name":"Vitae","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90550777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-08DOI: 10.17533/udea.vitae.v27n1a01
Jonny Ariel Fajardo Daza, Frank Carlos Herrera Ruales, Carol Andrea Ibarra Cabrera
Background: The determination of polyphenols in cocoa beans allows the establishing of antioxidant properties of great benefit to this product. Objectives: Optimization of the ultrasound-assisted extraction method to determine the content of polyphenols in cocoa beans. Methods: Two experiments design stages were carried out to optimize the ultrasound-assisted extraction process of polyphenols from the cocoa bean. In the first experiment design stage, the adequate extraction solvent was determined; for this purpose, five types of solvents were evaluated through a completely random design unrestricted (CRD). In the second experiment stage, a central composite design 22 + star point (with two central points) was used, which was evaluated using the response surface methodology to determine the influence of the temperature, time, and solute / solvent ratio. Results: The experiment found that acetone: water: acetic acid (70: 29.5: 0.5) mixture, leads to a greater amount of total extracted phenols measured for the Folin-Ciocalteu method. Analysis of variance (ANOVA) found that six significant effects that influence the response variable (total phenols extracted). The main effects were of the three factors and three of their interactions. Conclusions: After the optimizing said factors, an optimal point was found: 39.3 °C oftemperature, 74.5 minutes, and 22.8 mL of solvent per gram of cocoa sample.
背景:测定可可豆中多酚的含量可以建立对该产品有很大好处的抗氧化特性。目的:优化超声辅助提取可可豆中多酚含量的方法。方法:通过两个实验设计阶段对可可豆中多酚的超声辅助提取工艺进行优化。在第一个实验设计阶段，确定了合适的提取溶剂;为此，通过完全随机设计不受限制(CRD)对五种溶剂进行了评估。实验第二阶段，采用22 +星点(2个中心点)的中心复合设计，采用响应面法评估温度、时间和溶质/溶剂比的影响。结果:实验发现丙酮:水:乙酸(70:29.5:0.5)的混合物，导致总提取酚的量较大，可用于Folin-Ciocalteu法测定。方差分析(ANOVA)发现六个显著影响响应变量(总酚提取)。主要影响因素是这三个因素以及它们之间的三个相互作用。结论:对上述因素进行优化后，找到了一个最佳点:温度39.3℃，时间74.5 min，溶剂用量22.8 mL / g可可样品。
{"title":"OPTIMIZATION OF ULTRASOUND ASSISTED EXTRACTION OF POLYPHENOLS IN COCOA BEANS","authors":"Jonny Ariel Fajardo Daza, Frank Carlos Herrera Ruales, Carol Andrea Ibarra Cabrera","doi":"10.17533/udea.vitae.v27n1a01","DOIUrl":"https://doi.org/10.17533/udea.vitae.v27n1a01","url":null,"abstract":"Background: The determination of polyphenols in cocoa beans allows the establishing of antioxidant properties of great benefit to this product. Objectives: Optimization of the ultrasound-assisted extraction method to determine the content of polyphenols in cocoa beans. Methods: Two experiments design stages were carried out to optimize the ultrasound-assisted extraction process of polyphenols from the cocoa bean. In the first experiment design stage, the adequate extraction solvent was determined; for this purpose, five types of solvents were evaluated through a completely random design unrestricted (CRD). In the second experiment stage, a central composite design 22 + star point (with two central points) was used, which was evaluated using the response surface methodology to determine the influence of the temperature, time, and solute / solvent ratio. Results: The experiment found that acetone: water: acetic acid (70: 29.5: 0.5) mixture, leads to a greater amount of total extracted phenols measured for the Folin-Ciocalteu method. Analysis of variance (ANOVA) found that six significant effects that influence the response variable (total phenols extracted). The main effects were of the three factors and three of their interactions. Conclusions: After the optimizing said factors, an optimal point was found: 39.3 °C oftemperature, 74.5 minutes, and 22.8 mL of solvent per gram of cocoa sample.","PeriodicalId":51213,"journal":{"name":"Vitae","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89548455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-07DOI: 10.17533/UDEA.VITAE.V26N2A01
Diana Margarita MÁRQUEZ FERNÁNDEZ
Multiple researches have allowed the development of nanoencapsulation techniques that ease the controlled or targeted release of bioactive components and favor their incorporation in different foods and medication formulations to improve their bioavailability. Recent studies have facilitated the development of nanoencapsulation systems of different active ingredients for functional foods, comprising phenolic compounds, antioxidants, essential oils, minerals, flavors, fish oils, essential fatty acids, vitamins, antimicrobials, soluble fiber, peptides, lycopene, lutein, β-carotene, phytosterols, iron, calcium, among others, as well as bioactive compounds for therapeutic applications as polyphenols, curcumin, quercetin, resveratrol and epigallocatechin-3-gallate.
{"title":"Nanoencapsulation of bioactive ingredients: trends in pharmaceutical industry and functional foods","authors":"Diana Margarita MÁRQUEZ FERNÁNDEZ","doi":"10.17533/UDEA.VITAE.V26N2A01","DOIUrl":"https://doi.org/10.17533/UDEA.VITAE.V26N2A01","url":null,"abstract":"Multiple researches have allowed the development of nanoencapsulation techniques that ease the controlled or targeted release of bioactive components and favor their incorporation in different foods and medication formulations to improve their bioavailability. Recent studies have facilitated the development of nanoencapsulation systems of different active ingredients for functional foods, comprising phenolic compounds, antioxidants, essential oils, minerals, flavors, fish oils, essential fatty acids, vitamins, antimicrobials, soluble fiber, peptides, lycopene, lutein, β-carotene, phytosterols, iron, calcium, among others, as well as bioactive compounds for therapeutic applications as polyphenols, curcumin, quercetin, resveratrol and epigallocatechin-3-gallate.","PeriodicalId":51213,"journal":{"name":"Vitae","volume":"31 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.17533/UDEA.VITAE.V26N2A01","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72486957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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