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Reply regarding: “Optimizing non-pharmacological strategies for UEVT prevention: Standard care and IPC in TBI patients with PICCs—Letter on Liang et al.” 回复:“优化UEVT预防的非药物策略:piccs TBI患者的标准护理和IPC - letter on Liang等人。”
IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE Pub Date : 2025-11-06 DOI: 10.1016/j.aucc.2025.101458
Hongmei Liang RD, MSN, Long Liu MD
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引用次数: 0
Feasibility and pilot studies in critical care—Our top five lessons learnt as early- and mid-career researchers in Australia and New Zealand 重症监护的可行性和试点研究——我们在澳大利亚和新西兰作为职业生涯早期和中期的研究人员吸取的五大经验教训
IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE Pub Date : 2025-11-06 DOI: 10.1016/j.aucc.2025.101464
Kimberley J. Haines PhD, BHSc Physiotherapy , Antony Attokaran MBBS, FRACP, FCICM , Lee-anne Chapple BMedSci, MNutrDiet, PhD, APD , Julieann Coombes PhD , Bianca Crichton (Tainui, Ngāti Awa) BHealSc , Alisa M. Higgins PhD, MPH, BPhysio(Hons) , Carol Hodgson BAppSc(PT) FAAHMS FACP , Belinda Howe RN, BAppSc(Nursing), CCCert, MPH , Diane Mackle PhD, MN, BHSc (Nursing) , Alexis Poole BNSc(Hons), GDip.NSc Intensive Care, GCert.NSc Retrieval, PhD , Emma J. Ridley BNutriDietet, PhD , Manoj Saxena PhD, MB BChir, BSc(Immunology), FCICM , Neil Glassford BSc MBChB GCertClinUS PhD MRCP FCICM
Feasibility and pilot studies are an essential step in the development of clinical trials evaluating the effect of an intervention on patient-centred outcomes. Yet, challenges exist related to obtaining funding and conducting feasibility and pilot studies. This commentary provides an overview of five important areas of focus for early-career researchers (and is more broadly applicable), which emerged from a programmed session on feasibility and pilot studies at the 25th Annual Meeting on Clinical Trials in Intensive Care by the Australia and New Zealand Intensive Care Society Clinical Trials Group. The five areas included are as follows: (i) Building a program of research; (ii) Obtaining funding; (iii) Methodological excellence; (iv) Building a successful and diverse research team; and (v) Engaging with the clinical coalface.
可行性和试点研究是临床试验发展的重要步骤,评估干预措施对以患者为中心的结果的影响。然而,在获得资金和进行可行性研究和试点研究方面存在挑战。本评论概述了早期职业研究人员关注的五个重要领域(并且更广泛适用),这些领域来自澳大利亚和新西兰重症监护学会临床试验小组在第25届重症监护临床试验年会上关于可行性和试点研究的计划会议。包括的五个领域如下:(i)建立一个研究方案;获得经费;方法卓越;(四)建立一支成功和多样化的研究队伍;(五)与临床煤层接触。
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引用次数: 0
Comment on “Intermittent pneumatic compression can reduce the incidence of upper extremity venous thrombosis after peripherally inserted central catheter placement in traumatic brain injury patients: A randomised controlled trial” 《一项随机对照试验:间歇性气动压缩可降低外伤性脑损伤患者外周置管后上肢静脉血栓的发生率》
IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE Pub Date : 2025-11-06 DOI: 10.1016/j.aucc.2025.101463
S Dhanya Dedeepya MD, Vaishali Goel PhD, Nivedita Nikhil Desai MD
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引用次数: 0
Parents’ and nurses’ experiences of end-of-life care in intensive care for children: A systematic review 儿童重症监护中父母和护士临终关怀的经验:系统回顾
IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE Pub Date : 2025-11-01 DOI: 10.1016/j.aucc.2025.101455
Melissa J. Bloomer RN, PhD, FACCCN , Ashleigh E. Butler RN, PhD, MACCCN , Laura A. Brooks RN, PhD, MACCCN , Alysia Coventry RN, MPhil MACCCN , Stephen McKeever RGN, PhD, MACCCN , Kristen Ranse RN, PhD, MACCCN , Jessie Rowe BN (Hons), Grad Dip Nurs Pract Paed Crit Care, MACCCN , Shontelle Thomas Grad Cert Nurse Pract Paed Intens Care, BN, MACCCN , Rebecca Thornton RN, PhD, MACCCN

Background

The provision of end-of-life care for children in intensive care is a stressful and traumatic event for parents with immediate and life-long impacts. End-of-life care for children is also challenging for critical care nurses who must balance the child’s clinical requirements concurrently with facilitating and supporting the needs of parents and family members.

Research question

What is the research evidence about nurses’ and parents’ experiences of the provision of end-of-life care in intensive care for children?

Review methods

Following registration with the International Prospective Register of Systematic Reviews, a systematic review was undertaken. A combination of keywords, synonyms, and Medical Subject Headings were used across Cumulative Index for Nursing and Allied Health (CINAHL) Complete, Medline, and APA PsycInfo databases. Papers were independently assessed against inclusion and exclusion criteria. Included papers were assessed for quality. Narrative synthesis was used to analyse and present the findings.

Findings

From 40,904 records screened, 55 research publications were included, representing the perspectives of nurses, mothers, fathers, extended family, and legal guardians. Narrative synthesis revealed seven themes identified from the nurse and parent experiences: (i) communication; (ii) end-of-life decision-making; (iii) suffering; (iv) preparing for death; (v) at the end of life; (vi) after death; and (vii) nurse impacts. While there was mostly concordance between nurse and parent experiences, there was some discord between parents’ communication needs and nurses’ understanding of their role in communication. This review also highlighted how nurses commit to supporting parents in their grief and bereavement while concurrently managing their own emotions in response to a child’s death.

Conclusion

A child’s death cannot always be prevented. By exploring nurses’ and parents’ experiences of end-of-life care, as they occur simultaneously and in parallel, it is possible to build understanding and evolve practices to improve the experience of end-of-life care for children for all involved.
为重症监护儿童提供临终关怀对父母来说是一个压力和创伤事件,具有直接和终身的影响。对于重症监护护士来说,儿童的临终关怀也是一项挑战,他们必须在儿童的临床需求与促进和支持父母和家庭成员的需求之间取得平衡。研究问题:关于在重症监护中为儿童提供临终关怀的护士和父母的经验的研究证据是什么?在国际前瞻性系统综述注册后,进行了系统综述。关键词、同义词和医学主题标题的组合在护理和联合健康累积索引(CINAHL)完整、Medline和APA PsycInfo数据库中使用。根据纳入和排除标准对论文进行独立评估。对纳入的论文进行质量评估。叙述性综合用于分析和呈现研究结果。研究结果从40904份记录中筛选,包括55份研究出版物,代表了护士、母亲、父亲、大家庭和法定监护人的观点。叙事综合揭示了从护士和父母的经历中确定的七个主题:(i)沟通;(ii)临终决策;(3)痛苦;(四)为死亡作准备;(v)生命结束时;(六)死后;(七)护士影响。护士与父母的沟通需求基本一致,但父母的沟通需求与护士对沟通角色的理解不一致。这篇综述还强调了护士如何致力于在悲伤和丧亲之痛中支持父母,同时在应对孩子死亡时管理自己的情绪。结论儿童的死亡并非总是可以避免的。通过探索护士和父母在临终关怀方面的经验,因为它们同时发生并并行发生,有可能建立理解并发展实践,以改善所有相关人员对儿童临终关怀的体验。
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引用次数: 0
Optimising intermittent pneumatic compression for peripherally inserted central catheter–related thrombosis prevention in traumatic brain injury: A critical appraisal of Liang et al.’s randomised controlled trial 在外伤性脑损伤中,优化间歇性气动压缩以预防外周插入中心导管相关血栓形成:对Liang等人随机对照试验的关键评价
IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE Pub Date : 2025-11-01 DOI: 10.1016/j.aucc.2025.101457
Parth Aphale Ph.D, Shashank Dokania BHMS, Himanshu Shekhar BHMS
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引用次数: 0
The use of large data sets in clinical research: Don't throw the baby out with the bathwater 在临床研究中使用大数据集:不要把婴儿连同洗澡水一起倒掉。
IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE Pub Date : 2025-11-01 DOI: 10.1016/j.aucc.2025.101489
Andrea P. Marshall RN, PhD
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引用次数: 0
Effects of neuromuscular electrical stimulation on recovery in intensive care units: An umbrella review 神经肌肉电刺激对重症监护病房患者康复的影响:综述。
IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE Pub Date : 2025-11-01 DOI: 10.1016/j.aucc.2025.101456
Joana Vila Pouca RN, MN , Narcisa Gonçalves RN, MN , Carla Silvia Fernandes RN, Phd

Aim

The aim of this umbrella review was to synthesise existing evidence from systematic reviews on the impact of neuromuscular electrical stimulation on recovery in intensive care units.

Methods

This umbrella review was conducted in accordance with the Joanna Briggs Institute methodological guidance, and its reporting followed the Preferred Reporting Items for Overviews of Reviews statement. The search was carried out in the databases Medline®, CINAHL®, Scopus®, SciELO®, Web of Science®, Cochrane®, and SportDiscus®, using both indexed terms specific to each database and free-text terms. To assess the methodological quality of the included systematic reviews, the AMSTAR 2, tool was usedcovering 16 domains related to review design and reporting quality. The search was conducted with no temporal limits, until December 2024.

Results

A total of 21 systematic reviews were included. The most frequently assessed outcomes were muscle strength, muscle mass, and duration of mechanical ventilation. Muscle strength was the most extensively investigated outcome, with 11 reviews reporting positive effects. The analysis of primary study overlap revealed a moderate degree of overlap (6.71%).

Conclusion

It is concluded that neuromuscular electrical stimulation is safe for critically ill patients, with positive effects on muscle strength, muscle mass, and the duration of mechanical ventilation. Although neuromuscular electrical stimulation demonstrates promising results in the rehabilitation of critically ill patients, the methodological quality of the available systematic reviews is variable. Therefore, there is a need for more robust and high-quality systematic reviews to strengthen the evidence base.
目的:本综述的目的是综合现有的关于神经肌肉电刺激对重症监护病房康复影响的系统综述证据。方法:该总括性综述按照Joanna Briggs研究所的方法指南进行,其报告遵循综述声明的首选报告项目。在Medline®、CINAHL®、Scopus®、SciELO®、Web of Science®、Cochrane®和SportDiscus®数据库中进行检索,使用每个数据库特定的索引术语和自由文本术语。为了评估纳入的系统评价的方法学质量,使用了AMSTAR 2工具,涵盖了与评价设计和报告质量相关的16个领域。搜寻工作一直持续到2024年12月,没有时间限制。结果:共纳入21篇系统评价。最常见的评估结果是肌肉力量、肌肉质量和机械通气持续时间。肌肉力量是研究最广泛的结果,有11篇综述报告了积极的效果。初级研究重叠分析显示有中等程度的重叠(6.71%)。结论:神经肌肉电刺激对危重患者是安全的,对肌力、肌量、机械通气时间均有积极影响。虽然神经肌肉电刺激在危重病人的康复中显示出有希望的结果,但现有系统评价的方法学质量是可变的。因此,需要更有力和高质量的系统评价来加强证据基础。
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引用次数: 0
Systematic review and meta-analysis of intensive care unit outcomes in critically ill nonagenarians versus octogenarians: Impact on mortality, morbidity, and treatment intensity 重症监护病房结果的系统回顾和荟萃分析:对死亡率、发病率和治疗强度的影响
IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE Pub Date : 2025-11-01 DOI: 10.1016/j.aucc.2025.101454
Nattaya Raykateeraroj MD , Laurence Weinberg MD, PhD , Chayanan Thanakiattiwibun Msc , Suchanun Lao-amornphunkul MD , Nuanprae Kitisin MD

Introduction

As life expectancy increases, intensive care units (ICUs) are treating more patients aged 90 years and older. Whether outcomes in nonagenarians differ significantly from those of octogenarians (aged 80–89 years) remains uncertain.

Objective

The objective of this study was to compare ICU, in-hospital, and longer-term mortality (3 months–1 year) and treatment intensity between critically ill nonagenarians and octogenarians.

Methods

We conducted a systematic review and meta-analysis following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Ovid MEDLINE, Embase, and CENTRAL were searched through October 2024. Studies reporting outcomes for both age groups were included. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using random-effect models.

Results

Eleven retrospective studies were included, involving 138,073 ICU patients (13,717 nonagenarians and 124,356 octogenarians). ICU mortality was comparable overall (OR: 1.30, 95% CI: 0.94–1.80), although heterogeneity was high (I2 = 87%). In-hospital mortality (OR: 1.20, 95% CI: 1.04–1.39, I2 = 82%) and longer-term mortality (OR: 1.65, 95% CI: 1.58–1.72, I2 = 0%) were significantly higher among nonagenarians. Use of renal replacement therapy was significantly lower in nonagenarians (OR: 0.35, 95% CI: 0.26–0.48). Sensitivity analysis excluding short-stay ICU admissions revealed increased ICU mortality in nonagenarians (OR: 1.46, 95% CI: 1.06–2.02), suggesting that the initial comparability may underestimate true differences.

Conclusion

Observed similarities in ICU mortality may reflect selection bias towards less severely ill nonagenarians. When short-stay admissions were excluded, a consistent pattern of worse outcomes emerged. These findings highlight the need for individualised ICU decision-making in the oldest old and support future research using matched cohorts that account for illness severity, treatment intensity, and frailty to better understand the true impact of advanced age.
随着预期寿命的增加,重症监护病房(icu)治疗的90岁及以上患者越来越多。九十岁老人的预后是否与八十岁老人(80-89岁)有显著差异仍不确定。目的本研究的目的是比较危重的九十岁和八十岁老人的ICU、住院和长期死亡率(3个月- 1年)和治疗强度。方法我们按照系统评价和荟萃分析指南的首选报告项目进行了系统评价和荟萃分析。Ovid MEDLINE, Embase和CENTRAL在2024年10月之前都进行了搜索。研究报告了两个年龄组的结果。采用随机效应模型计算合并优势比(ORs)和95%置信区间(ci)。结果纳入6项回顾性研究,共纳入138073例ICU患者(其中老年13717例,老年124356例)。ICU死亡率总体上具有可比性(OR: 1.30, 95% CI: 0.94-1.80),尽管异质性很高(I2 = 87%)。住院死亡率(OR: 1.20, 95% CI: 1.04-1.39, I2 = 82%)和长期死亡率(OR: 1.65, 95% CI: 1.58-1.72, I2 = 0%)在百岁老人中显著较高。使用肾脏替代疗法的老年人明显较低(OR: 0.35, 95% CI: 0.26-0.48)。排除短期ICU住院的敏感性分析显示,老年患者ICU死亡率增加(OR: 1.46, 95% CI: 1.06-2.02),表明最初的可比性可能低估了真正的差异。结论观察到的ICU死亡率的相似性可能反映了对病情较轻的老年患者的选择偏差。当排除短期住院的情况时,出现了一贯的更糟糕的结果模式。这些发现强调了对老年患者进行个性化ICU决策的必要性,并支持未来的研究,使用匹配的队列,考虑疾病严重程度、治疗强度和虚弱程度,以更好地了解老年的真正影响。
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引用次数: 0
The experiences and challenges of caring for a healthcare professional patient in intensive and acute care settings: A cross-sectional exploratory survey 在重症和急性护理环境中护理医疗保健专业患者的经验和挑战:一项横断面探索性调查
IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE Pub Date : 2025-11-01 DOI: 10.1016/j.aucc.2025.101453
Lynne Hunt RN, BN(Hons), Melissa Riegel RN, PhD, Robyn Gallagher RN, PhD, Thomas Buckley RN, PhD

Background

Hospital admission can be a stressful experience for patients and their families. Although healthcare professionals can also be patients, there is limited understanding of nurses’ experiences when caring for them in hospital settings.

Aim

The aims of this study were to explore the challenges nurses encounter while caring for hospitalised healthcare professionals and to compare experiences between participants in intensive care unit and acute care settings.

Methods

A cross-sectional exploratory study was conducted in July 2022 using an online survey via Research Electronic Data Capture (REDCap) with registered nurses who had cared for a healthcare professional-patient within the previous 3 years.

Results

Sixty-nine participants were included, with a mean age of 44.8 years and a mean of 18.8 years of experience as a registered nurse; 49% worked in intensive care and 51% in acute care settings, including surgery, emergency, and cardiology. A substantial 63.7% reported that caring for healthcare professional-patients was more challenging, while 49.3% found it more stressful than caring for non–healthcare professional-patients. Only 3% had received prior education that supported them in this role, despite 87% feeling prepared to deliver care and 75% feeling comfortable doing so. Open-ended questions reflecting on their experience caring for healthcare professional-patients generated three themes: enhanced support and knowledge needed to facilitate the role reversal of healthcare professionals becoming patients, recognising and respecting the evolving dynamics in caring for healthcare professionals as patients, and tailoring communication to align with individual needs and prior knowledge. There were no differences between intensive care unit participants and acute care participants regarding feeling prepared, experiencing stress, or feeling challenged caring for health professional-patients.

Conclusion

In conclusion, many nurses face significant challenges and heightened stress while caring for hospitalised healthcare professionals, whether in intensive care or acute care environments. The findings highlight a critical need for enhanced training and support to address the unique dynamics and communication requirements of these situations.
住院对病人和他们的家人来说是一段压力很大的经历。虽然医疗保健专业人员也可能是病人,但对护士在医院照顾他们时的经验了解有限。目的本研究的目的是探讨护士在照顾住院医疗保健专业人员时遇到的挑战,并比较重症监护病房和急性护理环境参与者之间的经验。方法于2022年7月通过研究电子数据采集(REDCap)进行在线调查,对在过去3年内照顾过医疗保健专业患者的注册护士进行横断面探索性研究。结果共纳入69人,平均年龄44.8岁,注册护士年龄18.8岁;49%在重症监护室工作,51%在急症护理机构工作,包括外科、急诊和心脏病学。63.7%的受访者表示,照顾医疗保健专业患者更具挑战性,而49.3%的受访者认为照顾非医疗保健专业患者的压力更大。只有3%的人接受过支持他们担任这一角色的先前教育,尽管87%的人觉得准备好提供护理,75%的人觉得这样做很舒服。开放式问题反映了他们照顾医疗保健专业人员患者的经验,产生了三个主题:加强支持和知识,以促进医疗保健专业人员成为患者的角色转换,认识和尊重护理医疗保健专业人员作为患者的不断变化的动态,以及根据个人需求和先前的知识定制沟通。重症监护室的参与者和急症护理的参与者在照顾健康专业患者的感觉准备、经历压力或感觉挑战方面没有差异。总之,无论是在重症监护室还是在急症监护室,许多护士在照顾住院医疗保健专业人员时都面临着重大挑战和更高的压力。调查结果强调,迫切需要加强培训和支助,以解决这些情况的独特动态和沟通需求。
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引用次数: 0
The development and feasibility of a psychologist-led screening and modular-based psychological intervention in an Australian intensive care unit: A pilot study. 心理学家主导的筛选和基于模块的心理干预在澳大利亚重症监护病房的发展和可行性:一项试点研究。
IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE Pub Date : 2025-11-01 Epub Date: 2025-08-07 DOI: 10.1016/j.aucc.2025.101301
Jessica M Hampton, Elizabeth C Ward, Lynette Morrison, Kellie Sosnowski, James Banham, Marilia Libera, Chanelle Louwen, Hayden White, Rachael Watson, Melissa A Day

Background: Psychological distress is common among intensive care unit (ICU) patients and can lead to long-term adverse psychological sequelae. While early psychological interventions may help mitigate these effects, their feasibility within critical care settings remains largely unexplored. Additionally, the role of psychologists in delivering such interventions in Australia remains unclear, particularly given inconsistencies in workforce availability and integration into standard care.

Aims/objectives: The aim of this study was to (i) outline the development of a psychologist-led screening and intervention protocol in an Australian ICU and (ii) evaluate its preliminary feasibility. It also examined the suitability of a potential outcome measure to inform future trial design.

Methods: The Medical Research Council's framework for developing complex interventions in health was applied. The intervention was designed for an Australian metropolitan ICU. It consisted of a modular-based psychological intervention tailored to the patient's level of psychological distress. A single-arm prospective pilot study was conducted, and 30 patients were recruited. Feasibility was assessed based on recruitment rates, patient engagement, and outcome measure completion.

Results: Recruitment challenges were observed, with a low eligibility screening rate. Staffing constraints and consent-related barriers further limited recruitment. Intervention engagement was high, with 96% of consenting participants completing at least one intervention component. Outcome measure completion rates supported the feasibility of a larger trial, with preliminary findings suggesting a significant reduction in negative emotional affect over time. Consistent with the Medical Research Council's framework, refinements to the intervention are recommended.

Conclusions: The findings support the feasibility of a psychologist-led intervention in the ICU, though refinements are necessary to improve recruitment, streamline delivery, and enhance engagement. This study highlights the potential of early psychological interventions to improve patients' emotional well-being. Addressing staffing limitations and consent barriers could enhance accessibility and effectiveness in future trials.

Registration: This trial was registered with the Australian New Zealand Clinical Trials Registry (ACTRN12623000619640), with the first participant recruited on 4/07/2023.

背景:心理困扰在重症监护病房(ICU)患者中很常见,并可导致长期的不良心理后遗症。虽然早期心理干预可能有助于减轻这些影响,但其在重症监护环境中的可行性在很大程度上仍未得到探索。此外,心理学家在澳大利亚提供此类干预措施方面的作用尚不清楚,特别是考虑到劳动力可用性和融入标准护理的不一致性。目的/目的:本研究的目的是(i)概述澳大利亚ICU中心理学家主导的筛查和干预方案的发展,(ii)评估其初步可行性。它还检查了潜在结果测量的适用性,以告知未来的试验设计。方法:采用医学研究理事会制定的制定复杂卫生干预措施的框架。该干预措施是为澳大利亚大都市ICU设计的。它包括一个基于模块的心理干预量身定制的病人的心理困扰水平。进行了一项单臂前瞻性先导研究,招募了30名患者。可行性根据招募率、患者参与度和结果测量完成情况进行评估。结果:观察到招募困难,合格筛选率低。人员配备限制和与同意有关的障碍进一步限制了征聘。干预的参与度很高,96%的同意参与者完成了至少一个干预部分。结果测量完成率支持更大规模试验的可行性,初步结果表明,随着时间的推移,负面情绪影响显著减少。根据医学研究理事会的框架,建议对干预措施进行改进。结论:研究结果支持在ICU进行心理学家主导的干预的可行性,尽管需要改进以改善招募、简化交付和增强参与。这项研究强调了早期心理干预对改善患者情绪健康的潜力。解决人员配备限制和同意障碍可以提高未来试验的可及性和有效性。注册:该试验已在澳大利亚新西兰临床试验注册中心注册(ACTRN12623000619640),第一位受试者于2023年7月4日招募。
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Australian Critical Care
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