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Improved pregnancy rate and sex ratio in fresh/frozen in vivo derived embryo transfer of Hanwoo (Bos taurus coreanae) cows. 提高韩宇牛体内新鲜/冷冻胚胎移植的受孕率和性别比。
IF 2.3 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-07-01 Epub Date: 2023-07-30 DOI: 10.5187/jast.2023.e69
Jihyun Park, Wonyou Lee, Islam M Saadelin, Seonggyu Bang, Sanghoon Lee, Junkoo Yi, Jongki Cho

This study aimed to assess the effects of embryonic developmental stage, quality grade, and fresh or frozen/thawed conditions on the pregnancy rate and sex ratio of live offspring in Hanwoo (Bos taurus coreanae) cows. The quality and developmental stage of in vivo-derived (IVD) transferred embryos were evaluated using the standard criteria of the International Embryo Technology Society. The recipient cows were synchronized using conventional (estradiol benzoate and progesterone) protocols before embryo transfer. Embryos were transferred to 297 cows, and pregnancy was monitored for 60-70 days after embryo transfer. The pregnancy rates of fresh and frozen/thawed embryos were 56.90% and 52.49%, respectively. Pregnancy rates varied according to embryo quality (56.18% for grade 1 vs. 36.67% for grade 2). Pregnancy rates also varied by developmental stage and cryopreservation (67.86% vs. 63.49% for stage 4-1, 64.00% vs. 54.72% for 5-1, and 50.00% vs. 47.83% for 6-1, in fresh embryos vs. frozen/thawed embryos, respectively). For stage 7-1, the pregnancy rates were 72.73% for fresh embryos and 20.00% for frozen/thawed embryos. In 66 fresh embryos, the sex ratio of live offspring was 5:5, whereas it was 4(female):6(male) for frozen/thawed embryos among the 95 frozen/thawed embryos. The miscarriage rate was approximately 3% higher for frozen/thawed embryos than for fresh embryos (18.1% for fresh vs. 21.1% for frozen). Seasonal fertility rates were 33.3% in spring, 55.67% in summer, 52.8% in autumn, 60.0% in winter. The following male-to-female ratios were observed in different seasons: 6.7:3.3 in spring, 4.0:6.0 in summer, 5.5:4.5 in autumn, and 3.3:6.7 in winter. The current data revealed no significant differences in pregnancy rates between fresh and frozen/thawed IVD embryos. However, there was a lower pregnancy rate with advanced-stage frozen/thawed embryos (stage 7-1). The current study provides comprehensive results for the better optimization of embryo transfer in Hanwoo cattle to obtain the desired fertility rate, pregnancy rate, and sex ratio of calves. These results provide important insights into the factors that influence the viability and success of IVD embryo transfer in Hanwoo cows and may have practical applications for improving breeding programs and reducing production costs.

本研究旨在探讨胚胎发育阶段、品质等级、新鲜或冷冻/解冻条件对韩牛(Bos taurus coreanae)活仔受孕率和性别比例的影响。采用国际胚胎技术学会的标准对体外移植胚胎的质量和发育阶段进行评价。在胚胎移植前,使用传统的(苯甲酸雌二醇和黄体酮)方案对受体奶牛进行同步。将胚胎移植到297头奶牛身上,胚胎移植后监测妊娠60-70天。新鲜胚胎和冻融胚胎的受孕率分别为56.90%和52.49%。妊娠率因胚胎质量而异(1级为56.18%,2级为36.67%)。在新鲜胚胎与冷冻/解冻胚胎中,妊娠率也因发育阶段和冷冻保存而异(4-1期67.86%对63.49%,5-1期64.00%对54.72%,6-1期50.00%对47.83%)。在7-1期,新鲜胚胎的妊娠率为72.73%,冷冻/解冻胚胎的妊娠率为20.00%。66个新鲜胚胎的活子代性别比为5:5,而95个冷冻/解冻胚胎的活子代性别比为4(雌性):6(雄性)。冷冻/解冻胚胎的流产率比新鲜胚胎高约3%(新鲜胚胎18.1%比冷冻胚胎21.1%)。季节生育率分别为春季33.3%、夏季55.67%、秋季52.8%、冬季60.0%。不同季节的男女比例分别为:春季6.7:3.3,夏季4.0:6.0,秋季5.5:4.5,冬季3.3:6.7。目前的数据显示,新鲜和冷冻/解冻体外受精胚胎的妊娠率没有显著差异。然而,晚期冷冻/解冻胚胎(7-1期)的妊娠率较低。本研究为更好地优化韩宇牛胚胎移植,获得理想的受孕率、受孕率和犊牛性别比提供了全面的结果。这些结果对影响韩宇奶牛IVD胚胎移植存活率和成功率的因素提供了重要的见解,并可能在改进育种计划和降低生产成本方面具有实际应用价值。
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引用次数: 0
“It’s different for heterosexuals”: exploring cis-heteronormativity in COVID-19 public health directives and its impacts on Canadian gay, bisexual, and queer men “异性恋者不同”:探索新冠肺炎公共卫生指令中的顺式异性恋及其对加拿大男同性恋、双性恋和酷儿的影响
IF 2.8 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-06-28 DOI: 10.1080/09581596.2023.2226807
E. Daroya, M. Gaspar, Cornel Grey, D. Lessard, B. Klassen, S. Skakoon-Sparling, J. Sinno, Barry Adam, A. Perez-Brumer, N. Lachowsky, Jordan M. Sang, T. Hart, J. Cox, D. Tan, D. Grace
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引用次数: 1
E-cigarette flavours and vaping as a social practice: implications for tobacco control 电子烟口味和电子烟作为一种社会实践:对烟草控制的启示
IF 2.8 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-06-20 DOI: 10.1080/09581596.2023.2226806
M. Blank, J. Hoek
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引用次数: 0
The Public-in-Waiting: Children’s representation and inclusion in Aotearoa New Zealand’s COVID-19 public health response 等待的公众:儿童在新西兰新冠肺炎公共卫生应对中的代表性和包容性
IF 2.8 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-06-20 DOI: 10.1080/09581596.2023.2227334
J. Spray, Samantha Samaniego
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引用次数: 0
Do you see the problem? Visualising a generalised 'complex local system' of antibiotic prescribing across the United Kingdom using qualitative interview data. 你看到问题了吗?使用定性访谈数据可视化英国各地抗生素处方的通用“复杂地方系统”
IF 2.8 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-06-13 eCollection Date: 2023-01-01 DOI: 10.1080/09581596.2023.2210743
Rebecca E Glover, Nicholas B Mays, Alec Fraser

Antimicrobial resistance (AMR) is often referred to as a complex problem embedded in a complex system. Despite this insight, interventions in AMR, and in particular in antibiotic prescribing, tend to be narrowly focused on the behaviour of individual prescribers using the tools of performance monitoring and management rather than attempting to bring about more systemic change. In this paper, we aim to elucidate the nature of the local antibiotic prescribing 'system' based on 71 semi-structured interviews undertaken in six local areas across the United Kingdom (UK). We applied complex systems theory and systems mapping methods to our qualitative data to deepen our understanding of the interactions among antibiotic prescribing interventions and the wider health system. We found that a complex and interacting set of proximal and distal factors can have unpredictable effects in different local systems in the UK. Ultimately, enacting performance management-based interventions in the absence of in-depth contextual understandings about other pressures prescribers face is a recipe for temporary solutions, waning intervention effectiveness, and unintended consequences. We hope our insights will enable policy makers and academics to devise and evaluate interventions in future in a manner that better reflects and responds to the dynamics of complex local prescribing systems.

摘要抗微生物耐药性(AMR)通常被称为嵌入复杂系统中的复杂问题。尽管有这一见解,但AMR的干预措施,特别是抗生素处方的干预措施往往狭隘地关注个体处方医生的行为,使用绩效监测和管理工具,而不是试图带来更系统的改变。在本文中,我们旨在根据在英国六个地方进行的71次半结构化访谈,阐明当地抗生素处方“系统”的性质。我们将复杂系统理论和系统映射方法应用于我们的定性数据,以加深我们对抗生素处方干预措施和更广泛的卫生系统之间相互作用的理解。我们发现,在英国不同的地方系统中,一组复杂且相互作用的近端和远端因素可能会产生不可预测的影响。最终,在对处方医生面临的其他压力缺乏深入的背景理解的情况下,制定基于绩效管理的干预措施是一种临时解决方案,以及意想不到的后果。我们希望我们的见解将使政策制定者和学者能够在未来制定和评估干预措施,更好地反映和应对复杂的当地处方系统的动态。
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引用次数: 0
The quest for diffusible community health worker projects and the pitfalls of scaling culture 寻求可扩散的社区卫生工作者项目和规模文化的陷阱
IF 2.8 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-05-26 DOI: 10.1080/09581596.2023.2214689
Luis Aue, Tine Hanrieder
ABSTRACT Researchers of community health worker (CHW) models in many countries are looking for ways to scale without losing one of their main advantages, their context-sensitivity. This paper looks at one research strategy to make CHW projects scalable, namely by developing a generic notion of culture-sensitivity. Based on in-depth qualitative analysis, we reconstruct how ‘culture’ has been enshrined in a US-based CHW project and specifically in the artefact of a binder with teaching materials for vulnerable mothers. The inscription of generalized, culture-sensitive spaces into the binder did allow the Project to comply with standards of evidence-based medicine while respecting community self-determination and made space for creative and competent CHW practices. Yet at the same time, it took away from more substantive conceptions of community engagement and from community empowerment through CHWs. Our analysis highlights how the focus on culture can invisibilise and displace the importance of competent CHW practice and processes of community engagement.
摘要:许多国家的社区卫生工作者(CHW)模式的研究人员正在寻找在不失去其主要优势之一——环境敏感性的情况下扩大规模的方法。本文着眼于一种使CHW项目可扩展的研究策略,即通过开发文化敏感性的通用概念。基于深入的定性分析,我们重建了“文化”是如何体现在美国CHW项目中的,特别是在为弱势母亲准备教材的活页夹中。在活页夹中加入广义的、对文化敏感的空间确实使该项目符合循证医学的标准,同时尊重社区自决权,并为创造性和胜任的CHW实践腾出了空间。然而,与此同时,它剥夺了更实质性的社区参与概念和通过CHW赋予社区权力的概念。我们的分析强调了对文化的关注如何掩盖并取代CHW实践和社区参与过程的重要性。
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引用次数: 0
“A change in the narrative, a change in consensus”: the role of Deep End networks in supporting primary care practitioners serving areas of blanket socioeconomic deprivation “叙事的改变,共识的改变”:深端网络在支持为全面社会经济剥夺地区服务的初级保健从业人员中的作用
IF 2.8 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-05-08 DOI: 10.1080/09581596.2023.2205569
J. Wildman, S. Sowden, C. Norman
ABSTRACT England’s primary care crisis threatens the ability of general practice to play its role in the latest attempts to address the nation’s stubbornly persistent health inequalities. The primary care crisis is particularly acute in areas of blanket socioeconomic deprivation, where need is greatest. Deep End networks of general practitioners (GPs) are being established in the UK, and internationally, in response to the challenges of delivering primary care in deprived areas. As part of the co-creation of a Deep End network in the North East and North Cumbria, in this study we capture the challenges of delivering primary care in socioeconomically deprived areas that, if not addressed, threaten ambitions to reduce health inequalities. We also explore ways in which a Deep End network could support delivery of more effective primary care. In-depth interviews were conducted between September 2020 and April 2021 with 15 practitioners working in Deep End general practices in North East and North Cumbria. We find that the Deep End metaphor is apposite: it is the volume of clinical and social patient need that creates burdens for Deep End practitioners. We also find a severe mismatch between the demands of caring for Deep End communities and the fantasy paradigm that expects GPs to address health inequalities while failing to redistribute resources to areas of greatest need. We identify practitioners’ hopes for a Deep End network that delivers initiatives tailored to patients’ needs, gives a name to their struggles, and advocates for wider healthcare system recognition of deprivation, and a funding formula that recognises need.
英国的初级保健危机威胁到全科医生在解决国家顽固持续的健康不平等的最新尝试中发挥作用的能力。初级保健危机在全面的社会经济剥夺地区尤其严重,那里的需求最大。为了应对在贫困地区提供初级保健的挑战,英国和国际上正在建立全科医生(gp)的深层网络。作为东北和北坎布里亚郡深端网络共同创建的一部分,在这项研究中,我们抓住了在社会经济贫困地区提供初级保健的挑战,如果不解决这些挑战,就会威胁到减少健康不平等的雄心。我们还探讨了如何使深端网络能够支持提供更有效的初级保健。在2020年9月至2021年4月期间,对在东北和北坎布里亚郡的深端全科诊所工作的15名从业者进行了深入访谈。我们发现深端比喻是恰当的:它是临床和社会病人的需求量,创造负担深端从业者。我们还发现,在照顾深端社区的需求与期望全科医生解决健康不平等问题而未能将资源重新分配到最需要的地区的幻想范式之间存在严重的不匹配。我们确定了从业者对Deep End网络的希望,该网络提供针对患者需求的举措,为他们的斗争命名,并倡导更广泛的医疗保健系统认识到剥夺,以及认识到需求的资助公式。
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引用次数: 0
Changing school cultures for mental wellbeing in Hong Kong: the potential of pedagogic practices that take power into account 改变学校文化以促进香港的心理健康:考虑到权力的教学实践的潜力
IF 2.8 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-05-08 DOI: 10.1080/09581596.2023.2207721
L. Tang, P. Tsui, A. K. Shum, W. G. Leung, D. Lung, P. Ng, Kenus P. Y. Leung, Paul S. F. Yip
ABSTRACT School-based programs are recommended by the World Health Organization (WHO) to promote mental health for young people. However the effectiveness of such programs varies, and there are multi-level challenges to embedding mental health education in schools. Further, critical scholarship has focused on the ways in which such programs can contribute to neoliberal goals, rather than empowering students meaningfully. Our research used focus group interviews to capture the perspectives and experiences of teachers and children participating in a school-based program in Hong Kong. We applied Bernstein’s theory of pedagogic practices to analyze the interview data, in particular the concepts of boundaries and framing. We identified rigid boundaries between classrooms, the wider school, and home. Boundaries between academic and wider learning, and between school leaders and teachers, hindered cultural change towards mental wellbeing in schools. The program in this study reduced boundaries between students, and between students and teachers. This enhanced students’ communication, and bonding with peers and teachers. School culture about mental health education was found to have weak framing, with students having more influence on the learning process in this program than they currently do in other subjects. We argue that understanding boundaries and framing underpins development of better pedagogic practices in mental health education. When rooted in careful analysis of power relationships with school cultures, mental health promotion is not necessarily aligned with dominant values in society that privilege academic success over wellbeing. School-based programs can provide co-learning spaces for teachers and students, that encourage learning about mental health.
世界卫生组织(WHO)推荐以学校为基础的项目来促进青少年的心理健康。然而,这些计划的有效性各不相同,并且在学校中嵌入心理健康教育存在多层次的挑战。此外,批判性学术关注的是这些项目如何为新自由主义目标做出贡献,而不是有意义地赋予学生权力。我们的研究采用焦点小组访谈的方式来捕捉参与香港校本项目的教师和儿童的观点和经验。我们运用伯恩斯坦的教学实践理论来分析访谈数据,特别是边界和框架的概念。我们在教室、更广阔的学校和家之间划定了严格的界限。学术和广泛学习之间的界限,以及学校领导和教师之间的界限,阻碍了学校对心理健康的文化变革。这项研究中的项目减少了学生之间以及学生和老师之间的界限。这加强了学生之间的交流,以及与同学和老师之间的联系。心理健康教育的学校文化框架较弱,学生对心理健康教育的学习过程的影响比目前在其他科目上的影响更大。我们认为,理解边界和框架是心理健康教育中更好的教学实践发展的基础。在仔细分析学校文化与权力关系的基础上,促进心理健康并不一定符合社会的主流价值观,即把学业成功置于幸福之上。以学校为基础的项目可以为教师和学生提供共同学习的空间,鼓励学习心理健康知识。
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引用次数: 1
Using Habermas’ theory of communicative action to transform sociological analyses of evidence-based policy 运用哈贝马斯的交往行为理论改造循证政策的社会学分析
IF 2.8 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-04-21 DOI: 10.1080/09581596.2023.2204182
C. Bonell, G. Melendez‐Torres
ABSTRACT Many sociological analyses of evidence-based policy frame it as contributing to the rationalisation of social relations, and being constructed through and implicated in systems of knowledge/power. These analyses are based on social theory placing insufficient emphasis on the emancipatory potential of evidence, and the possibility of rational adjudication of truth claims. We argue sociological engagement with evidence-based policy could be transformed by being informed by the work of Habermas. Habermas’ work could enable a more nuanced view of EBP in terms of whether or not this leads to rationalisation in the form of de-politicisation or marginalisation of citizens’ voices. Habermas’ work on knowledge-constitutive interests could inform a reconstructed view of evidence, disabused of positivist assumptions and with increased emancipatory potential. Habermas’ notion of the ideal speech situation as a procedural basis for truth could function as a standard for exploring how EBP is affected by power asymmetries, as well as for adjudicating truth claims.
许多基于证据的政策的社会学分析将其框架为有助于社会关系的合理化,并且通过知识/权力系统构建并涉及其中。这些分析是基于社会理论,对证据的解放潜力和对真理主张的理性裁决的可能性重视不够。我们认为,社会学对基于证据的政策的参与可以通过哈贝马斯的工作来改变。哈贝马斯的工作可以让我们对EBP有一个更细致入微的看法,即这是否会以公民声音的去政治化或边缘化的形式导致合理化。哈贝马斯关于知识构成利益的工作可以为重建证据的观点提供信息,消除实证主义假设的滥用,并具有更大的解放潜力。哈贝马斯关于理想言语情境作为真理的程序基础的概念,可以作为探索EBP如何受到权力不对称影响的标准,也可以作为裁决真理主张的标准。
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引用次数: 1
Using discursive approaches to examine the utility and functions of language in public health and health promotion: highlighting social constructions of e-cigarettes 使用话语方法考察语言在公共卫生和健康促进中的效用和功能:突出电子烟的社会结构
IF 2.8 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-04-19 DOI: 10.1080/09581596.2023.2201658
G. Wilson, J. Keenan, L. Porcellato, I. Gee, B. Gough, S. Grogan
ABSTRACT This article uses discursive approaches to examine the utility and functions of language in public health, focusing on social constructions of e-cigarettes. Due to the ambiguity surrounding the use of e-cigarettes, understanding may be negotiated collaboratively through co-construction in talk. Ten participants, three men and seven women aged 26–47 years, took part in two focus groups in Manchester, UK, where they discussed e-cigarettes. Data were analysed using blended discourse analysis, with a view to identifying dominant repertoires used by speakers. Participants drew from two discursive frameworks to communicate perceptions of e-cigarettes: (1) uncertainty and risk and (2) the social acceptability and stigma spectrum. The ambiguity surrounding e-cigarettes was reflected in the linguistic devices used in talk. This article demonstrates the value of drawing on discourse analysis to better understand the impact of health-related communication by providing insight into how existing messages are interpreted, co-constructed, and assigned meaning through shared interactions.
摘要本文采用话语的方法来考察语言在公共卫生中的效用和功能,重点关注电子烟的社会结构。由于电子烟的使用存在歧义,可以通过对话中的共建来协商理解。10名参与者,3男7女,年龄26-47岁 多年来,他参加了英国曼彻斯特的两个焦点小组,在那里他们讨论了电子烟。使用混合话语分析对数据进行分析,以确定演讲者使用的主要曲目。参与者从两个话语框架中交流对电子烟的看法:(1)不确定性和风险;(2)社会可接受性和污名谱。围绕电子烟的歧义反映在谈话中使用的语言手段上。本文通过深入了解如何通过共享互动来解释、共同构建和分配现有信息,展示了利用话语分析更好地理解健康相关沟通的影响的价值。
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引用次数: 1
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Critical Public Health
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