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Post-infectious bronchiolitis obliterans secondary to adenovirus 继发于腺病毒的感染后阻塞性支气管炎
Pub Date : 2024-02-21 DOI: 10.60147/8ef93f7f
Sara Beltrán, Elena Aranda, Carlos Martín, Mercedes Odriozola, Mercedes Cemeli
Bronchiolitis obliterans is a rare chronic obstructive respiratory disease secondary to damage of the lower respiratory tract causing inflammation and partial or total obliteration of it. There are different causes, being infectious the most frequent in pediatrics, mainly due to adenovirus. We present the case of an 18-month-old male infant with a history of admission to the Pediatric Intensive Care Unit at 8 months of age due to bronchitis secondary to respiratory syncytial virus and adenovirus. After this episode, he presented persistent respiratory distress and pathological pulmonary auscultation. High resolution pulmonary computed tomography showed a mosaic pattern with areas of air trapping and decreased vascular caliber in the affected areas, findings suggestive of bronchiolitis obliterans.
阻塞性支气管炎是一种罕见的慢性阻塞性呼吸道疾病,继发于下呼吸道损伤,导致炎症和部分或全部阻塞。发病原因多种多样,在儿科最常见的是感染性疾病,主要由腺病毒引起。本病例是一名 18 个月大的男婴,8 个月大时因继发于呼吸道合胞病毒和腺病毒的支气管炎被送入儿科重症监护室。这次发病后,他出现了持续性呼吸困难和病理性肺部听诊。高分辨率肺部计算机断层扫描显示,受影响区域出现空气潴留和血管口径减小的马赛克模式,结果提示为阻塞性支气管炎。
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引用次数: 0
Melatonin in sleep disorders. comparison of different products and literature review 褪黑素治疗睡眠障碍:不同产品的比较和文献综述
Pub Date : 2024-02-07 DOI: 10.60147/45efa623
Victoria Domínguez, Beatriz Flores, Cristóbal Coronel
Introduction: sleep disorders in paediatrics are a growing problem. Melatonin is the drug of choice and it is common to receive advertising for multiple products containing melatonin in primary care. In this paper, a comparative analysis of these products is carried out, examining the most recent scientific evidence, in order to determine whether their use is justified or not. Methods: a descriptive study was conducted on melatonin-containing products sold in pharmacies in Spain and aimed at the paediatric population. Subsequently, a systematic review of documents on the use of melatonin in children and on each extra component present in the products collected was carried out. Results: fifty-three products were analysed. The most common form of administration was drops or millilitres. The usual recommended dose of melatonin was 1 mg per day. The most frequently reported added component was vitamin B6, and lemon balm and passionflower were the most frequently used herbs. None of the products were specifically listed in the Spanish Agency for Medicines and Health Products, and no bibliographical references were found in the advertising of any of the products. Conclusions: although the efficacy of melatonin in sleep disorders is well known, there is currently no consensus on its effective dose in children. The substances most frequently associated with melatonin have little literature to support their results in sleep, and there are no standardised doses for them either, or doses lower than these are used due to a lack of studies in the paediatric population.
导言:儿科睡眠障碍是一个日益严重的问题。褪黑素是首选药物,在初级保健中经常会收到含有褪黑素的多种产品的广告。本文对这些产品进行了比较分析,研究了最新的科学证据,以确定其使用是否合理。方法:对西班牙药店出售的针对儿科人群的含褪黑素产品进行了描述性研究。随后,对有关褪黑素在儿童中的使用以及所收集产品中每种额外成分的文件进行了系统性审查。结果:共分析了 53 种产品。最常见的给药形式是滴剂或毫升剂。褪黑素的推荐剂量通常为每天 1 毫克。最常报告的添加成分是维生素 B6,最常使用的草药是柠檬香膏和西番莲。这些产品均未在西班牙药品和保健品管理局的具体清单中列出,也未在任何产品的广告中发现任何参考文献。结论:虽然褪黑激素对睡眠障碍的疗效众所周知,但目前对其在儿童中的有效剂量还没有达成共识。最常与褪黑激素联系在一起的物质很少有文献支持其在睡眠方面的效果,而且也没有标准剂量,或者由于缺乏对儿科人群的研究,使用的剂量低于标准剂量。
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引用次数: 0
Adequacy of medical prescriptions in streptococcal pharyngitis and acute otitis media to therapeutic guidelines 链球菌性咽炎和急性中耳炎的医疗处方是否符合治疗指南的要求
Pub Date : 2024-02-05 DOI: 10.60147/c4a39d2d
Marcelo Vivas, Beatriz Barbarin, Silvia García de Garayo, José Tomás Ramos
Background and objective: to analyze the degree of adequacy to consensus therapeutic guidelines in acute pharyngotonsillitis and acute otitis media of primary care pediatricians. Material and Methods: retrospective observational study with data collection from electronic medical records of patients with suppurative AOM and streptococcal AAF in patients from 0 to 14 years of age residing in Araba, in an 18-month period study. Results: in the group of patients with suppurative AOM, 238 episodes have been evaluated, with a degree of therapeutic adequacy of 56.7%, being underdosing the main cause of inadequacy. In the group of patients with streptococcal AAF, 1721 episodes have been evaluated, with a degree of therapeutic adequacy of 57%, being the main causes of inadequacy overdose and short-duration regimens. Conclusion: in both suppurative AOM and streptococcal AAF, the degree of therapeutic adequacy is somewhat lower than in other analysed studies. To achieve a correct treatment in these processes in primary care settings is of vital importance due to its high frequency of diagnosis. It is also important to improve the quality of registered data in medical records of all patients.
背景和目的:分析初级保健儿科医生对急性咽炎和急性中耳炎的共识治疗指南的掌握程度。材料和方法:回顾性观察研究,从居住在阿拉巴的 0 至 14 岁化脓性 AOM 和链球菌性 AAF 患者的电子病历中收集数据,研究为期 18 个月。结果:在化脓性 AOM 患者组中,共评估了 238 次病例,治疗充分度为 56.7%,用药不足是造成治疗充分度不足的主要原因。在链球菌性 AAF 患者组中,共评估了 1721 次病例,治疗充分度为 57%,用药过量和疗程过短是导致治疗充分度不足的主要原因。结论:化脓性 AOM 和链球菌性 AAF 的治疗充分性略低于其他分析研究。由于这些疾病的诊断频率很高,因此在基层医疗机构对这些疾病进行正确治疗至关重要。此外,提高所有患者病历中登记数据的质量也很重要。
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引用次数: 0
Alice in Wonderland syndrome in SARS-CoV-2 infection SARS-CoV-2 感染者的爱丽丝梦游仙境综合征
Pub Date : 2024-01-24 DOI: 10.60147/1dec69fd
Sara Beltrán, Eva M.ª Jiménez, Paula Vidal, M.ª Pilar Vicente, Mercedes Cemeli
The Alice in Wonderland syndrome is defined by the presence of visual perception disorders with several etiologies, being the most frequent the infections in pediatrics. It is a rare clinical condition, but it is important to recognize it because of the generally self-limited nature. We present a 11 years old child who presented visual body distortions, micropsia and macropsia 48 after SARS-CoV-2 infection. Other organic causes were discarded, maintaining an expectant treatment because of its benign evolution. To point this syndrome associated with SARS-CoV-2 infection, has not yet published right now.
爱丽丝梦游仙境综合症(Alice in Wonderland Syndrome)是由多种病因引起的视觉感知障碍,是儿科最常见的感染性疾病。这是一种罕见的临床病症,但由于其通常具有自限性,因此识别这种病症非常重要。我们报告了一名 11 岁儿童在感染 SARS-CoV-2 48 天后出现的视体变形、小视点和大视点。由于该病是良性发展,因此排除了其他器质性病因,并坚持期待疗法。目前还没有人发表过这种与 SARS-CoV-2 感染相关的综合征。
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引用次数: 0
Growth and pubertal development in girls adopted from Russia: 12-year follow-up 从俄罗斯收养的女孩的生长和青春期发育:12 年的跟踪调查
Pub Date : 2024-01-22 DOI: 10.60147/43e0f65f
Gonzalo Oliván
Introduction: the objectives were to provide longitudinal data on growth and determine the age of thelarche and menarche in girls adopted from Russia. Material and methods: prospective cohort study in 24 girls from Russia adopted in Spain in the 2002-2010 period, who were followed up for 12 years. The history of adverse childhood experiences was collected by reviewing pre-adoption medical records. We recorded standardised measurements of weight, height and head circumference and the age at thelarche and menarche. The mean values were compared with reference standards. Results: Salient history: preterm birth (33.3%), low birth weight (41.7%), prenatal alcohol exposure (45.8%), abuse and neglect (54.2%). Initial evaluation: mean age, 3 years (standard deviation [SD] 1.6) years; weight z-score (z), −1.35; height z, −2.42; head circumference z −1.77. One year after adoption, there was significant catch-up growth in weight (z +0.68), height (z +0.98), and head circumference (z +0.76). Temporal trends in growth: no weight delay from age 7 years; height continued to recover until age 10 (z −0.40) and remained stable until age 15 (z −0.46); the delay was greater compared to weight at every timepoint. The mean age at onset of thelarche was 9.9 years (SD 0.8) with a height of 135.4 cm (z −0.43). The mean age at menarche was 11.9 years (SD 0.7) years, with a height of 147.6 cm (z −0.44). Conclusions: the pattern of growth and development was characterized by severe delay in linear growth and a moderate delay in weight and head circumference at the time of adoption, rapid, significant and prolonged catch-up growth, acceleration of pubertal development with early thelarche and menarche and an incomplete recovery of linear growth.
导言:目的是提供纵向生长数据,并确定从俄罗斯收养的女孩的初潮和月经初潮年龄。材料与方法:对 2002-2010 年期间在西班牙收养的 24 名俄罗斯女孩进行了为期 12 年的前瞻性队列研究。我们通过查阅收养前的医疗记录,收集了她们童年的不良经历。我们记录了体重、身高和头围的标准化测量值,以及初潮和月经初潮的年龄。将平均值与参考标准进行比较。结果主要病史:早产(33.3%)、出生体重不足(41.7%)、产前饮酒(45.8%)、虐待和忽视(54.2%)。初步评估:平均年龄 3 岁(标准差 [SD] 1.6);体重 z 值(z)-1.35;身高 z 值-2.42;头围 z 值-1.77。采用该方法一年后,体重(z +0.68)、身高(z +0.98)和头围(z +0.76)均有明显的追赶性增长。生长的时间趋势:体重从 7 岁起没有延迟;身高在 10 岁前持续恢复(z -0.40),并在 15 岁前保持稳定(z -0.46);与体重相比,每个时间点的延迟都更大。月经初潮的平均年龄为 9.9 岁(SD 0.8),身高 135.4 厘米(z -0.43)。月经初潮的平均年龄为 11.9 岁(标准差 0.7),身高为 147.6 厘米(z -0.44)。结论:生长发育模式的特点是:收养时线性生长严重延迟,体重和头围中度延迟,追赶性生长迅速、显著且持续时间长,青春期发育加速,月经初潮和初潮提前,线性生长未完全恢复。
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引用次数: 0
Effectiveness of theoretical-practical training in basic life support for school canteen monitors from Primary Care 学校食堂初级保健监督员基本生命支持理论-实践培训的效果
Pub Date : 2024-01-17 DOI: 10.60147/a767b139
Gustavo Andrés Salom, Natalia Campos
Introduction: cardiovascular diseases constitute a public health problem worldwide and among them cardiorespiratory arrest (CPA) stands out. School canteens are spaces with potential risk of witnessing a PCR. Materials and methods: quasi-experimental analytical study of intervention. The participants received training through an interactive virtual platform and a face-to-face clinical simulation session on the Heimlich maneuver, basic cardiopulmonary resuscitation (CPR) and the use of the semiautomatic external defibrillator (SAED). A descriptive analysis of the study population and a comparative statistical analysis between the results obtained in a test before and after the virtual training were carried out. A variable was created by subtracting the score obtained before training from that obtained after it. Clinical simulation was analyzed by direct observation. Statistical significance was defined as p < 0.05. Statistical analysis with SPSS version 19.0. The principles of the Declaration of Helsinki and the guidelines on good clinical practice were followed. Results: the entire sample was women with a median age of 48.50 years. The median mark of the pre-test was 6.7/10 and the post-test had a constant result of 10/10. The difference between the post-test and the pre-test had a median of 3.3 (p 0.01) and was found in the simulation that the learning was optimal. Conclusions: training in CPR is a strategy with a social impact, related to an improvement in the response to a case of CPA, reducing the morbidity and mortality that this implies.
导言:心血管疾病是全世界的公共卫生问题,其中心肺骤停(CPA)尤为突出。学校食堂是可能发生 PCR 的场所。材料和方法:准实验性干预分析研究。参与者通过互动虚拟平台和面对面的临床模拟课程接受海姆立克急救法、基本心肺复苏术(CPR)和半自动体外除颤器(SAED)使用的培训。对研究对象进行了描述性分析,并对虚拟培训前后的测试结果进行了比较统计分析。通过将培训前的得分减去培训后的得分,创建了一个变量。通过直接观察对临床模拟进行分析。统计学意义的定义是 p < 0.05。使用 SPSS 19.0 版进行统计分析。研究遵循了《赫尔辛基宣言》和良好临床实践指南的原则。结果:所有样本均为女性,年龄中位数为 48.50 岁。前测的中位数为 6.7/10,后测的恒定结果为 10/10。后测与前测的差异中位数为 3.3(P 0.01),在模拟中发现学习效果最佳。结论:心肺复苏术培训是一项具有社会影响的战略,它能提高对 CPA 病例的反应能力,降低发病率和死亡率。
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引用次数: 0
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Revista Pediatría Atención Primaria
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