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Vagus nerve size determined via ultrasonography is associated with white matter lesions in patients with vascular risk factors. 通过超声波检查确定的迷走神经大小与有血管风险因素患者的白质病变有关。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-07-29 DOI: 10.1007/s40477-024-00936-2
Tomohisa Nezu, Futoshi Eto, Akemi Hironaka, Shiro Aoki, Shuichiro Neshige, Saki Tasaka, Hikari Kirimoto, Hirofumi Maruyama

Purpose: The cross-sectional area (CSA) of the cervical vagus nerve (VN), as assessed through ultrasonography, might be linked to autonomic nervous system dysfunction. Hypertension is the primary factor associated with cerebral white matter lesions (WMLs), but there is also evidence of a connection with autonomic nervous system dysfunction. However, the associations between WMLs and VN size are unclear. Our objective was to investigate the associations between WMLs and VN size in patients with vascular risk factors.

Methods: The CSA of the VN was evaluated using carotid ultrasonography in patients with a history of stroke (acute or chronic) and comorbidities (n = 196, 70.2 ± 12.7 years). Common carotid artery (CCA) intima-media thickness and interadventitial diameter (IAD) were also measured. The severity of the WMLs was assessed by the Fazekas classification and Scheltens' scale.

Results: The CSA of the right VN (2.08 ± 0.65 mm2) was significantly greater than that of the CSA of the left VN (1.56 ± 0.44 mm2) (P < 0.001). Multiple linear regression analyses revealed that older age, hypertension, increased right CCA IAD, and decreased CSA of the right VN (standardized partial regression coefficient [β] - 0.226; P < 0.001) were independently associated with the severity of WMLs (Scheltens' scale). A decreased CSA of the left VN was also associated with the severity of WMLs (β = - 0.239; P < 0.001).

Conclusion: VN size determined via ultrasonography was associated with the severity of WMLs. While these findings do not establish a causal relationship, they suggest that autonomic nervous system dysfunction is involved in the progression of WMLs.

目的:通过超声波检查评估的颈迷走神经(VN)横截面积(CSA)可能与自主神经系统功能障碍有关。高血压是与脑白质病变(WMLs)相关的主要因素,但也有证据表明与自主神经系统功能障碍有关。然而,WMLs 与 VN 大小之间的关系尚不清楚。我们的目的是研究有血管风险因素的患者的 WMLs 与 VN 大小之间的关系:方法:对有中风(急性或慢性)病史和合并症的患者(n = 196,70.2 ± 12.7 岁)使用颈动脉超声波对 VN 的 CSA 进行评估。此外,还测量了颈总动脉 (CCA) 的内膜厚度和动脉间直径 (IAD)。WMLs的严重程度由Fazekas分类法和Scheltens量表进行评估:结果:右侧 VN 的 CSA(2.08 ± 0.65 mm2)明显大于左侧 VN 的 CSA(1.56 ± 0.44 mm2):通过超声波检查确定的 VN 大小与 WML 的严重程度有关。虽然这些发现并不能确定因果关系,但它们表明自律神经系统功能障碍与 WMLs 的进展有关。
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引用次数: 0
Effects of superficial tissue and intermuscular connections on rectus femoris muscle shear modulus heterogeneity. 表层组织和肌间连接对股直肌剪切模量异质性的影响
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2023-02-07 DOI: 10.1007/s40477-022-00769-x
Taiki Kodesho, Takuya Kato, Gakuto Nakao, Yu Yokoyama, Yuhei Saito, Kota Watanabe, Yuki Ohsaki, Masaki Katayose, Keigo Taniguchi

Introduction: Intramuscular heterogeneity exists in the shear modulus of the rectus femoris (RF) muscle. However, the underlying heterogeneity mechanisms are not entirely understood. Previous research has reported that detachment of superficial tissues reduces the shear modulus by 50%. The aim of this study was to examine the effects of the skin, deep fascia, and intermuscular connections on the shear modulus of the RF at multiple sites.

Materials and methods: Eleven donors were fixed using the Thiel method. Measurements were performed at 0°, 60°, and 120° knee flexion in a neutral hip position. Tissue processing was performed under four conditions: superficial tissue (CONT), skin off (SKIN), deep fascia detachment (FASC), and intermuscular connections detachment (ALL). The shear modulus at the proximal, central, and distal regions were measured using ultrasound shear wave elastography. The study was approved by the Sapporo Medical University Ethical Committee.

Results: Three-way ANOVA revealed no significant interaction between treatment, site, and angle (P = 0.156), treatment and angle (P = 0.067), or site and angle (P = 0.441). There was a significant effect of treatment (P < 0.001), site (P = 0.010), and angle (P < 0.001) and interaction between treatment and site (P < 0.001). The proximal shear modulus was greater than the central for CONT. There were no significant differences between the measurement sites for SKIN. The distal shear modulus was greater than the proximal for FASC. The distal shear modulus was also greater than the proximal and central for ALL.

Conclusions: Intramuscular regional differences that influence superficial tissue and intermuscular connections of RF elasticity heterogeneity were observed.

简介股直肌(RF)的剪切模量存在肌内异质性。然而,其潜在的异质性机制尚未完全明了。以前的研究报告称,表层组织的剥离会使剪切模量降低 50%。本研究的目的是检查皮肤、深筋膜和肌间连接对 RF 多个部位剪切模量的影响:采用蒂尔法固定 11 名供体。在中立髋位、膝关节屈曲 0°、60° 和 120°时进行测量。组织处理在四种条件下进行:表层组织(CONT)、皮肤剥离(SKIN)、深筋膜剥离(FASC)和肌间连接剥离(ALL)。使用超声剪切波弹性成像技术测量了近端、中央和远端区域的剪切模量。该研究获得了札幌医科大学伦理委员会的批准:三方方差分析显示,治疗、部位和角度(P = 0.156)、治疗和角度(P = 0.067)或部位和角度(P = 0.441)之间无显著交互作用。治疗方法有明显的影响(P 结论:P = 0.441):观察到了影响射频弹性异质性的表层组织和肌肉间连接的肌肉内区域差异。
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引用次数: 0
Evaluating acoustic and thermal properties of a plaque phantom. 评估斑块模型的声学和热学特性。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2023-04-08 DOI: 10.1007/s40477-023-00778-4
Michalis Sotiriou, Christakis Damianou

Purpose: The aim of this study is to evaluate the acoustic and thermal properties of a plaque phantom. This is very important for the effective implementation of ultrasound not only in diagnosis but especially in treatment for the future.

Material and methods: An evaluation of acoustic and thermal properties of plaque phantoms to test their suitability mainly for ultrasound imaging and therapy was presented. The evaluation included measurements of the acoustic propagation speed using pulse-echo technique, ultrasonic attenuation coefficient using through transmission immersion technique, and absorption coefficient. Moreover, thermal properties (thermal conductivity, volumetric specific heat capacity and thermal diffusivity) were measured with the transient method using a needle probe.

Results: It was shown that acoustic and thermal properties of atherosclerotic plaque phantoms fall well within the range of reported values for atherosclerotic plaque and slightly different for thermal diffusivity and volumetric specific heat capacity for soft tissues. The mean value of acoustic and thermal properties and their standard deviation of plaque phantoms were 1523 ± 23 m/s for acoustic speed, 0.50 ± 0.02 W/mK for thermal conductivity, 0.30 ± 0.21 db/cm-MHz for ultrasonic absorption coefficient and 1.63 ± 0.46 db/cm-MHz for ultrasonic attenuation coefficient.

Conclusions: This study demonstrated that acoustic and thermal properties of atherosclerotic plaque phantoms were within the range of reported values. Future studies should be focused on the optimum recipe of the atherosclerotic plaque phantoms that mimics the human atherosclerotic plaque (agar 4% w/v, gypsum 10% w/v and butter 10% w/v) and can be used for HIFU therapy.

目的:本研究旨在评估斑块模型的声学和热学特性。这对于未来有效实施超声诊断,尤其是治疗非常重要:材料和方法:对斑块模型的声学和热学特性进行了评估,以测试其是否适用于超声成像和治疗。评估包括使用脉冲回波技术测量声波传播速度、使用透射浸入技术测量超声衰减系数和吸收系数。此外,还使用针形探针以瞬态法测量了热特性(热导率、体积比热容和热扩散率):结果表明,动脉粥样硬化斑块模型的声学和热学特性完全符合动脉粥样硬化斑块的报告值范围,而软组织的热扩散率和体积比热容则略有不同。斑块模型声学和热学特性的平均值及其标准偏差分别为:声速(1523 ± 23 m/s)、导热系数(0.50 ± 0.02 W/mK)、超声吸收系数(0.30 ± 0.21 db/cm-MHz)和超声衰减系数(1.63 ± 0.46 db/cm-MHz):本研究表明,动脉粥样硬化斑块模型的声学和热学特性均在报告值范围内。今后的研究重点应放在模拟人类动脉粥样硬化斑块的动脉粥样硬化斑块模型的最佳配方上(琼脂 4% w/v、石膏 10% w/v 和黄油 10% w/v),并可用于 HIFU 治疗。
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引用次数: 0
The role of CEUS in the management of biloma. CEUS 在胆脂瘤治疗中的作用。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-01 Epub Date: 2024-02-08 DOI: 10.1007/s40477-023-00849-6
Valentina Marinato, Alice Phillips, Leonardo Giuliano, Tommaso Cascella, Giorgio Greco, Rodolfo Lanocita

Background: A biloma refers to an abnormal, well-defined accumulation of bile outside the biliary tree within the abdomen, which can be either intra- or extra-hepatic in nature. It can result from traumatic or iatrogenic causes, leading to a disruption in the biliary system. Without prompt diagnosis and appropriate management, it can result in significant morbidity and mortality. While magnetic resonance cholangiopancreatography (MRCP) is the typical diagnostic method, there are instances where it may not provide conclusive results.

Case presentation: We present the case of a 72-year-old woman who underwent an hepatic resection of the seventh segment after recurrence of hepatocellular carcinoma (HCC). During the ultrasound (US) follow-up, she developed a peri-hepatic collection which proved to be a biloma continuously refurnished by the biliary tree. Neither the MRCP nor the percutaneous transhepatic cholangiography (PTC) were able to clearly detect the exact site of the bile leak. While awaiting the Endoscopic Retrograde Cholangio-Pancreatography (ERCP), a Contrast-Enhanced Ultrasound (CEUS) was conducted administering the contrast agent directly through the percutaneous drainage catheter placed in the biloma. This revealed the presence of contrast flow from the collection to a peripheral right bile duct, confirming the intra-hepatic leak communication.

Conclusions: This case demonstrates that Contrast-Enhanced Ultrasound (CEUS) presents a straightforward, secure, and precise approach to detect biliary leakage responsible for the formation of a biloma. Additionally, the adoption of CEUS offers the dual benefit of minimizing radiation exposure for the patient and obviating the requirement for anesthesia. In summary, CEUS emerges as a compelling alternative to conventional diagnostic methods for effectively managing a biloma.

背景:胆汁瘤是指胆汁在腹腔内胆管外的异常、明确的积聚,其性质可以是肝内或肝外的。它可能由外伤或先天性原因引起,导致胆道系统紊乱。如果没有及时诊断和适当的治疗,可能会导致严重的发病率和死亡率。虽然磁共振胆管胰管造影术(MRCP)是典型的诊断方法,但在某些情况下可能无法提供确诊结果:本病例是一名 72 岁女性的病例,她在肝细胞癌(HCC)复发后接受了第七段肝切除术。在超声波(US)随访期间,她出现了肝周积液,事实证明这是胆管树持续反流的胆汁瘤。无论是 MRCP 还是经皮经肝胆管造影术(PTC),都无法清楚地检测到胆漏的确切部位。在等待内镜逆行胰胆管造影术(ERCP)的过程中,进行了造影增强超声检查(CEUS),通过放置在胆囊内的经皮引流导管直接注入造影剂。结果显示,造影剂从胆汁淤积处流向右侧胆管外周,证实了肝内漏沟通:本病例表明,对比增强超声(CEUS)是一种直接、安全、精确的方法,可用于检测导致胆汁瘤形成的胆汁渗漏。此外,采用 CEUS 还具有双重优势,既能最大限度地减少对患者的辐射照射,又无需进行麻醉。总之,CEUS 是有效治疗胆汁瘤的传统诊断方法的一种令人信服的替代方法。
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引用次数: 0
Optimizing scapulothoracic injections: the role of hand positioning in enhancing procedural ease. 优化肩胛胸注射:手部定位在提高程序简便性中的作用。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-28 DOI: 10.1007/s40477-024-00947-z
Sonal Saran, Kapil Shirodkar, Mohsin Hussein, K Durgaprasad Bhamidipaty, Robert Henderson, Christine Azzopardi, G R Madhu Mallik, Karthikeyan P Iyengar, Rajesh Botchu

Introduction: Pathologies of the scapulothoracic articulation may lead to painful symptoms such as crepitus and bursitis. While conservative treatments are preferred, persistent symptoms may require image-guided injections. This study aims to determine the optimal hand positioning during ultrasound to maximize the distance between the scapula and thoracic wall, and improve its accessibility during injections.

Methods: This cross-sectional observational study included ten healthy adult volunteers without scapulothoracic issues or history of trauma/surgery. Two musculoskeletal radiologists independently measured the scapulothoracic distance on Ultrasound in three hand positions: 1. Hands under the head; 2. Hands by the side of the trunk; and 3. Hands hanging by the side of the couch. Data was analyzed using SPSS 24.0. Continuous variables were described using mean and standard deviation (SD), with significance set at p < 0.05.

Results: Measurements on 20 scapulothoracic articulations (10 volunteers) showed the following findings: Position 1: Baseline value of 1. Position 2: Distance increased by 1.515 mm ± 3.617 (95% CI [- 0.0178, 3.208]. Position 3: Distance increased by 2.175 mm ± 0.66 (95% CI [0.793, 3.557]. Statistical analysis indicated no significant difference (p = 0.39) between positions. However, both radiologists subjectively noted that positions 2 and 3 provided better access for interventions.

Conclusion: This study highlights the importance of hand positioning in optimizing the scapulothoracic distance for therapeutic interventions. While no significant statistical differences were found, the results suggest potential benefits for clinical practice. Further research with larger samples is needed to establish evidence-based guidelines for scapulothoracic injections.

简介肩胛胸关节的病变可能导致疼痛症状,如皱襞和滑囊炎。虽然保守治疗是首选,但持续的症状可能需要图像引导注射。本研究旨在确定超声波检查时的最佳手部定位,以最大限度地增加肩胛骨与胸壁之间的距离,并改善注射时的可及性:这项横断面观察研究包括 10 名健康的成年志愿者,他们没有肩胛胸问题或外伤/手术史。两名肌肉骨骼放射科医生分别用超声波测量了三种手位的肩胛胸距离:1.双手放在头部下方;2. 双手放在躯干一侧;3.双手悬挂在沙发边。数据使用 SPSS 24.0 进行分析。连续变量用平均值和标准差(SD)表示,显著性以 p 为标准:对 20 个肩胛胸关节(10 名志愿者)的测量结果如下:位置 1:基线值为 1。 位置 2:距离增加了 1.515 毫米 ± 3.617(95% CI [- 0.0178, 3.208])。位置 3:距离增加了 2.175 毫米 ± 0.66(95% CI [0.793,3.557])。统计分析表明,不同位置之间无明显差异(P = 0.39)。不过,两位放射科医生都主观地指出,2 号和 3 号体位能更好地进行介入治疗:这项研究强调了手部定位在优化肩胛胸距离以进行治疗干预方面的重要性。虽然没有发现明显的统计学差异,但结果表明对临床实践有潜在的益处。需要对更大的样本进行进一步研究,以建立以证据为基础的肩胛胸注射指南。
{"title":"Optimizing scapulothoracic injections: the role of hand positioning in enhancing procedural ease.","authors":"Sonal Saran, Kapil Shirodkar, Mohsin Hussein, K Durgaprasad Bhamidipaty, Robert Henderson, Christine Azzopardi, G R Madhu Mallik, Karthikeyan P Iyengar, Rajesh Botchu","doi":"10.1007/s40477-024-00947-z","DOIUrl":"https://doi.org/10.1007/s40477-024-00947-z","url":null,"abstract":"<p><strong>Introduction: </strong>Pathologies of the scapulothoracic articulation may lead to painful symptoms such as crepitus and bursitis. While conservative treatments are preferred, persistent symptoms may require image-guided injections. This study aims to determine the optimal hand positioning during ultrasound to maximize the distance between the scapula and thoracic wall, and improve its accessibility during injections.</p><p><strong>Methods: </strong>This cross-sectional observational study included ten healthy adult volunteers without scapulothoracic issues or history of trauma/surgery. Two musculoskeletal radiologists independently measured the scapulothoracic distance on Ultrasound in three hand positions: 1. Hands under the head; 2. Hands by the side of the trunk; and 3. Hands hanging by the side of the couch. Data was analyzed using SPSS 24.0. Continuous variables were described using mean and standard deviation (SD), with significance set at p < 0.05.</p><p><strong>Results: </strong>Measurements on 20 scapulothoracic articulations (10 volunteers) showed the following findings: Position 1: Baseline value of 1. Position 2: Distance increased by 1.515 mm ± 3.617 (95% CI [- 0.0178, 3.208]. Position 3: Distance increased by 2.175 mm ± 0.66 (95% CI [0.793, 3.557]. Statistical analysis indicated no significant difference (p = 0.39) between positions. However, both radiologists subjectively noted that positions 2 and 3 provided better access for interventions.</p><p><strong>Conclusion: </strong>This study highlights the importance of hand positioning in optimizing the scapulothoracic distance for therapeutic interventions. While no significant statistical differences were found, the results suggest potential benefits for clinical practice. Further research with larger samples is needed to establish evidence-based guidelines for scapulothoracic injections.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142094173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Point-of-care lung and inferior vena cava ultrasound in hemodialysis: more complex than it appears. 血液透析中的护理点肺部和下腔静脉超声:比表面看起来更复杂。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-25 DOI: 10.1007/s40477-024-00940-6
Amir Kazory, Olanrewaju A Olaoye, Abhilash Koratala
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引用次数: 0
BAASIK technique: an innovative single needle technique of performing shoulder corticosteroid injections. BAASIK 技术:进行肩部皮质类固醇注射的创新单针技术。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-22 DOI: 10.1007/s40477-024-00948-y
Nidhi Agrawal, Kapil Shirodkar, Sindhura Mettu, Ankit B Shah, Bipin R Shah, Karthikeyan P Iyengar, Rajesh Botchu

The novel BAASIK (B-Botchu,Bipin, A-Agrawal, A-Ankit, S- Sindhura, I-Iyengar, K- Kapil) technique is a combined ultrasound-guided injection into the subacromial-subdeltoid (SASD) bursa and the biceps tendon sheath to treat shoulder pain associated with biceps tendonitis/tendinopathy, subacromial bursitis, rotator cuff impingement or to determine the source of shoulder pain. This technique aims in reducing shoulder pain, improving functional activities and enhancing treatment delivery. A single-entry supine ultrasound-guided injection of the subacromial-subdeltoid (SASD) bursa and biceps tendon sheath involves using a single needle insertion point to access both structures for therapeutic injection. This technique could become a favoured alternative technique, rather than  subjecting patients to two needlesticks and preparing two separate injections to address often concomitant pathologies.

新颖的 BAASIK(B-Botchu,Bipin, A-Agrawal, A-Ankit, S- Sindhura, I-Iyengar, K- Kapil)技术是在超声波引导下对肩峰下滑囊和肱二头肌腱鞘进行联合注射,以治疗与肱二头肌肌腱炎/肌腱病、肩峰下滑囊炎、肩袖撞击有关的肩痛,或确定肩痛的来源。该技术旨在减轻肩部疼痛、改善功能活动并提高治疗效果。单进路仰卧超声引导下肩峰下滑囊和肱二头肌腱鞘注射是指使用单个针插入点进入这两个结构进行治疗性注射。这种技术可能成为一种受欢迎的替代技术,而不是让患者接受两次针刺和准备两次单独的注射,以解决往往同时存在的病理问题。
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引用次数: 0
Trans-axillary sonography in the ABER (ABduction and External Rotation) position: a window to the subscapularis, teres major and latissimus dorsi. ABER(ABduction and External Rotation,内收外旋)体位下的经腋窝超声造影:了解肩胛下肌、大圆肌和背阔肌的窗口。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-10 DOI: 10.1007/s40477-024-00924-6
Logeswaran Selvarajah, Mark Cresswell, Romain David, Paul Winston, Timothy Murray

Shoulder ultrasound is a key tool used by musculoskeletal practitioners to diagnose and treat a variety of upper girdle diseases. While magnetic resonance imaging is the cornerstone of shoulder imaging, sonography is readily available, practical and superior in its ability for dynamic assessment of musculoskeletal pathologies. The subscapularis, teres major and latissimus dorsi muscles are commonly involved in a myriad of pathology including myofascial pain and spasticity. There is scarce literature on the assessment of these muscles for diagnostic and therapeutic purposes. Conventional approaches to shoulder ultrasound have not included a dedicated assessment of the subscapularis muscle due to its inherent anatomical location deep to the scapular blade which blocks sound wave penetration. We describe an approach to visualizing the subscapularis muscle as a short addition to the established shoulder sonography format, which also permits assessment of both the latissimus dorsi and teres major muscles, which are important muscles for shoulder spasticity. The patient is imaged in a semi-recumbent position with the arms elevated above and behind the head in the ABduction and External Rotation (ABER) position. The relative ease of positioning and sonographic access to the musculature coupled with the potential for assessment and intervention makes this approach extremely desirable to the musculoskeletal practitioner looking to diagnose or treat muscle belly pathologies of the subscapularis, teres major or latissimus dorsi.

肩部超声是肌肉骨骼医生诊断和治疗各种上腰椎疾病的重要工具。虽然磁共振成像是肩部成像的基石,但超声波成像技术在动态评估肌肉骨骼病变方面具有方便、实用和优越性。肩胛下肌、大圆肌和背阔肌常见于各种病症,包括肌筋膜疼痛和痉挛。对这些肌肉进行诊断和治疗评估的文献很少。由于肩胛下肌位于肩胛骨的深处,其固有的解剖位置阻碍了声波的穿透,因此传统的肩部超声检查方法并不包括对肩胛下肌的专门评估。我们介绍了一种肩胛下肌可视化方法,它是对现有肩部超声造影方法的一个简短补充,同时还能评估背阔肌和大圆肌,这两块肌肉是肩部痉挛的重要肌肉。患者以半卧位进行成像,双臂抬高至头顶上方和后方,呈内收外旋 (ABER) 位。由于定位和声像图检查肌肉组织相对容易,而且具有评估和干预的潜力,因此这种方法对于希望诊断或治疗肩胛下肌、大圆肌或背阔肌肌腹病变的肌肉骨骼医生来说非常理想。
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引用次数: 0
Intra-articular and intraosseous approach to temporomandibular joint-targeted injections: a cadaveric investigation. 颞下颌关节靶向注射的关节内和骨内方法:尸体研究。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-08 DOI: 10.1007/s40477-024-00942-4
Ricardo de Souza Tesch, Esther Rieko Takamori, Rosana Bizon Vieira Carias, Juliana Oliveira de Medeiros Vilela, Thayanne Brasil Barbosa Calcia

Purpose: Temporomandibular joint osteoarthritis (TMJ-OA) management is complex, and several conservative and minimally invasive protocols have been proposed. Intra-articular injections of medications directed at OA have been performed, but in some cases, these medications do not directly contact the tissue lesion sites. Here, we propose a new real-time ultrasound-guided technique to inject medications directly into the subchondral bone.

Methods: Ultrasound image screening was carried out with the point-of-care Clarius L15 device. Then, with the patient's mouth closed, a stainless-steel cannula with a concentric trocar was US-guided using an in-plane approach until the perforating tip of the internal trocar touched the lateral pole of the mandibular condyle. Then, the trocar was inserted through the medullary bone, where a posterior injection was made.

Results: The technique's precision was confirmed by capturing an iodine contrast solution that imaged the medullary condyle of fresh anatomical specimens processed by computed tomography.

Conclusion: The proposed technique was effective in accessing the mandibular condyle subchondral bone in the inferior TMJ space for the simultaneously intra-articular (IA) and intra-osseous (IO) in-plane US-guided injections. Thus, its implementation may represent an important advance in early TMJ-OA treatment. This may be a promising approach, especially in OA cases in which the cortical bone is still preserved.

目的:颞下颌关节骨关节炎(TMJ-OA)的治疗非常复杂,目前已提出了几种保守和微创方案。针对 OA 的关节内药物注射已经开展,但在某些情况下,这些药物不能直接接触组织病变部位。在此,我们提出一种新的实时超声引导技术,将药物直接注入软骨下骨:方法:使用护理点 Clarius L15 设备进行超声图像筛查。然后,在患者闭口的情况下,在超声引导下使用平面内方法插入带有同心套管的不锈钢套管,直到内部套管的穿孔尖端接触到下颌骨髁状突的外侧极。然后,将套管插入髓质骨,进行后方注射:结果:通过捕捉碘造影剂溶液,对经计算机断层扫描处理的新鲜解剖标本的髓髁部进行成像,证实了该技术的精确性:结论:所提出的技术能有效进入颞下颌关节下间隙的下颌骨髁状突软骨下骨,同时进行关节内(IA)和骨内(IO)平面内 US 引导注射。因此,它的实施可能代表着早期颞下颌关节-OA 治疗的重要进步。这可能是一种很有前景的方法,尤其是在皮质骨仍被保留的 OA 病例中。
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引用次数: 0
Imaging of experimental venous thrombus by means of Doppler and CEUS techniques in dogs. 利用多普勒和 CEUS 技术对狗的实验性静脉血栓进行成像。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-06 DOI: 10.1007/s40477-024-00935-3
Mariana S Barbagianni, Stefanos G Georgiou, Pagona G Gouletsou, Apostolos D Galatos, Irene Valasi, Elena Pappa, Anargyros T Karatrantos, Athanasios Giannoukas

Venous thrombosis has been widely studied in humans, but not in dogs. This study was designed to evaluate a venous thrombus in dogs, from creation to solution, by means of various ultrasonographic techniques. Nine healthy Beagle dogs were included in the study. The venous thrombus was formatted by puncturing the lumen of the external jugular veins and then, the veins were examined with B-mode, color Doppler, pulsed-wave Doppler, and contrast-enhanced ultrasound (CEUS) techniques, at regular intervals, within 210-270 min after venipuncture. Haemodynamic parameters were calculated at two different locations, before and after the site of the thrombus formation. The existence of a thrombus was confirmed by CEUS technique. Thrombus volume and echogenicity were evaluated. The results showed that the visualization of the venous thrombus by color Doppler modality was not feasible in some veins. The blood volume was the parameter that could more precisely indicate the presence or absence of a thrombus. In cases where thrombus volume was less than 0.001 cm3, it was impossible to detect its presence using haemodynamic parameters. The CEUS imaging depicted accurately the size and shape of an anechoic venous thrombus, even when its volume was 0.001cm3.

静脉血栓已在人类身上得到广泛研究,但在狗身上还没有。本研究旨在通过各种超声波技术评估狗体内静脉血栓从形成到溶解的整个过程。九只健康的比格犬参与了这项研究。静脉血栓是通过穿刺颈外静脉管腔形成的,然后在静脉穿刺后 210-270 分钟内,每隔一定时间用 B 型、彩色多普勒、脉冲波多普勒和造影剂增强超声(CEUS)技术对静脉进行检查。在血栓形成部位前后两个不同位置计算血流动力学参数。通过 CEUS 技术确认血栓的存在。对血栓体积和回声进行了评估。结果显示,在某些静脉中,彩色多普勒模式无法显示静脉血栓。血容量是更能准确显示血栓存在与否的参数。在血栓体积小于 0.001 立方厘米的情况下,无法通过血流动力学参数检测血栓的存在。CEUS 成像能准确显示无回声静脉血栓的大小和形状,即使血栓体积只有 0.001 立方厘米。
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