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Time and State Opioid Legislation Have Reduced Opioid Filling in Elective Shoulder Surgery. 时间和州阿片类药物立法减少了选择性肩部手术中的阿片类药物填充。
Daniel J Cunningham, Jay Levin, Jeffrey O'Donnell, Joshua Helmkamp, Oke Anakwenze, Tally Lassiter, Mark J Gage, Christopher S Klifto

Opioid-limiting legislation has been enacted in response to the opioid epidemic in the United States. However, the impact of this legislation on perioperative opioid prescribing in elective shoulder surgery is not well understood. This is an observational review of 90-day perioperative opioid-prescription filling by patients undergoing shoulder surgery using a national insurance database (n = 231,634 patients) between 2010 and 2019. Statistics evaluated the impact of the year and opioid-limiting legislation on first prescription and cumulative 90-day opioid filling. Initial and cumulative opioid-prescription volume decreased significantly from 2010 to 2019 (49 to 44.4 initial oxycodone 5-mg equivalents, 132.8 to 72.3 cumulative oxycodone 5-mg equivalents; all p < 0.001). States with opioid-limiting legislation had larger reductions in initial and cumulative opioid-prescription filling over similar time frames (p < 0.001). Perioperative opioid prescribing has decreased significantly in shoulder surgery with time and state legislation. Individual prescribers and state and national legislators should continue to seek ways to reduce opioid overprescribing. (Journal of Surgical Orthopaedic Advances 33(3):152-157, 2024).

为应对阿片类药物在美国的流行,美国颁布了限制阿片类药物的法律。然而,这项立法对肩部择期手术围手术期阿片类药物处方的影响还不甚了解。这是一项观察性研究,利用国家保险数据库(n = 231,634 名患者)对 2010 年至 2019 年期间接受肩部手术的患者 90 天围手术期阿片类药物处方的填写情况进行回顾。统计评估了年份和阿片类药物限制法规对首次处方和 90 天阿片类药物累积用量的影响。从 2010 年到 2019 年,阿片类药物的首次处方量和累计处方量均大幅下降(首次 5 毫克羟考酮当量从 49 降至 44.4,累计 5 毫克羟考酮当量从 132.8 降至 72.3;所有 p <0.001)。有阿片类药物限制立法的州在相似的时间范围内阿片类药物初始处方量和累计处方量的减少幅度更大(p < 0.001)。随着时间的推移和各州立法的实施,肩部手术围手术期阿片类药物处方量明显减少。个人处方者以及州和国家立法者应继续寻求减少阿片类药物过量处方的方法。(外科骨科进展杂志》33(3):152-157,2024 年)。
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引用次数: 0
Liposomal Bupivacaine Use During Adolescent Idiopathic Scoliosis Surgery Decreases Postoperative Narcotic Usage.
Alexander H Jinnah, Rosser McCallie, Alejandro Marquez-Lara, Nicholas Tully, Michael S Hughes, John Frino

Postoperative pain control in adolescent patients following posterior spinal fusion (PSF) for adolescent idiopathic scoliosis (AIS) requires a multimodal pain regimen involving a combination of opioids and adjuvant analgesic medications. The purpose of this study was to identify whether the use of the local anesthetic liposomal bupivacaine (LB) at time of closure following PSF reduced postoperative narcotic use in patients when compared with an alternative local anesthetic. Twenty-five patients who received LB at time of wound closure were matched with 25 AIS patients from the year prior to minimize changes in protocol and instrumentation. Charts were retrospectively reviewed, and significant difference was found in age, gender, body mass index, length of stay, visual analog scores for pain, or number of levels fused. However, the LB group had significantly less morphine equivalent totals. Based on the results, the authors would recommend the use of LB during closure of PSF for AIS. (Journal of Surgical Orthopaedic Advances 33(4):219-221, 2024).

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引用次数: 0
Comparing Severity of Knee Arthritis at an Urban Center by Insurance Type Prior to Total Knee Arthroplasty. 比较城市中心全膝关节置换术前不同保险类型膝关节炎的严重程度。
Salvador G Ayala, Abhishek Deshpande, Michael J Patetta, Julio C Castillo Tafur, Ye Lin, Diego Barragan Echenique, Mark H Gonzalez

This study compares radiographic osteoarthritis severity prior with total knee arthroplasty (TKA) by payer type. Five hundred and three primary TKAs were included. Preoperative radiographs were scored by Ahlback, Kellgren-Lawrence (KL), and International Knee Documentation Committee (IKDC) classifications. Osteoarthritis severity by age and insurance type (private, Medicare, and Medicaid) were compared using Mann Whitney U and Kruskal-Wallis testing. Three hundred and two (60%) subjects were under 65 years old, and 201 (40%) were 65 years and older. Younger subjects had no differences in radiographic severity in KL (p = 0.268), Ahlback (p = 1), or IKDC (p = 0.948) classification by insurance. Older subjects also had no differences in osteoarthritis severity for KL (p = 0.282), Ahlback (p = 0.354), or IKDC (p = 0.735) classifications by insurance. Three osteoarthritis classification systems found no difference in preoperative radiographic changes by payor type, suggesting that, in the study's population, there is no delay in appropriate surgical treatment by payer. Future studies should compare preoperative clinical symptoms. (Journal of Surgical Orthopaedic Advances 33(3):184-188, 2024).

本研究按付款人类型比较了全膝关节置换术(TKA)前的放射骨关节炎严重程度。研究共纳入了 53 例初级 TKA。术前X光片按照Ahlback、Kellgren-Lawrence(KL)和国际膝关节文献委员会(IKDC)的分类进行评分。使用 Mann Whitney U 和 Kruskal-Wallis 检验比较了不同年龄和保险类型(私人、医疗保险和医疗补助)的骨关节炎严重程度。322名受试者(60%)的年龄在65岁以下,201名受试者(40%)的年龄在65岁及以上。在 KL(p = 0.268)、Ahlback(p = 1)或 IKDC(p = 0.948)分类中,较年轻的受试者在放射学严重程度上没有因保险而产生的差异。老年受试者的骨关节炎严重程度在 KL(p = 0.282)、Ahlback(p = 0.354)或 IKDC(p = 0.735)分类中也没有保险差异。三种骨关节炎分类系统的术前影像学变化在支付方类型上没有差异,这表明在该研究的人群中,支付方并没有延迟适当的手术治疗。未来的研究应比较术前临床症状。(外科骨科进展杂志》33(3):184-188,2024)。
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引用次数: 0
Risk Factors for Postoperative Deep Venous Thrombosis and Pulmonary Embolism Following Primary Total Hip Arthroplasty and Primary Total Knee Arthroplasty. 原发性全髋关节置换术和原发性全膝关节置换术术后深静脉血栓形成和肺栓塞的风险因素。
Catherine Raquel, Michael Zebold, Michael Foy, Anshum Sood, Mark Gonzalez

Pulmonary embolism (PE) and deep vein thrombosis (DVT) are common postoperative complications. This study retrospectively analyzes preoperative attributes as risk factors for DVT or PE following primary total hip arthroplasty (THA) and total knee arthroplasty (TKA). Preoperative transfusion, age 65+, dyspnea with moderate exertion, body mass index (BMI) 24.9+ were independent risk factors for PE following THA. Cardiac comorbidities were related with reduced risk. Bleeding disorder, operative time > 110 minutes, perioperative transfusion, age 65+, dyspnea at rest, and BMI < 18.5 were independent risk factors for DVT following THA. Perioperative transfusion, age 57+, dyspnea at rest and with moderate exertion, and BMI 24.9+ were independent risk factors for PE following TKA. Smoking status was related to reduced risk. Perioperative transfusion, age 65+, dyspnea with moderate exertion, and male sex were independent risk factors for DVT following TKA. Cardiac comorbidities were related with reduced risk. Identifying risk factors helps prevent DVT and PE after THA or TKA. (Journal of Surgical Orthopaedic Advances 33(3):138-142, 2024).

肺栓塞(PE)和深静脉血栓形成(DVT)是常见的术后并发症。本研究回顾性分析了初级全髋关节置换术(THA)和全膝关节置换术(TKA)术前作为深静脉血栓或肺栓塞风险因素的属性。术前输血、65 岁以上、中度用力呼吸困难、体重指数 (BMI) 24.9 以上是 THA 术后发生 PE 的独立风险因素。心脏病合并症与风险降低有关。出血障碍、手术时间大于 110 分钟、围手术期输血、年龄大于 65 岁、休息时呼吸困难和体重指数小于 18.5 是 THA 术后深静脉血栓形成的独立风险因素。TKA术后发生PE的独立风险因素包括围手术期输血、57岁以上、静息时和中度用力时呼吸困难以及体重指数24.9以上。吸烟与风险降低有关。围手术期输血、65 岁以上、中度劳累时呼吸困难和男性是 TKA 术后深静脉血栓形成的独立风险因素。心脏病合并症与风险降低有关。识别风险因素有助于预防THA或TKA术后深静脉血栓形成和PE。(外科骨科进展杂志》33(3):138-142,2024)。
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引用次数: 0
Assessment of Prophylactic Antibiotic Coverage in Culture-positive Traumatic Open Fractures. 评估培养阳性外伤性开放骨折的预防性抗生素覆盖率。
Rachel LaBianca Toler, Susan E Hamblin, Lauren E Mangan, J Myles Keck, Austin Ing, Matthew Felbinger, Cory Collinge, Bradley M Dennis

Guidelines provide varying recommendations for the prophylactic antimicrobial treatment of open fractures. This single-center, retrospective cohort study was conducted to determine how well an institutional prophylactic antibiotic protocol covered pathogens associated with open fractures. The authors included adult trauma patients with one or more open fractures and a positive culture from the site of the open fracture, and compared outcomes between patients who were covered by prophylactic antibiotics with patients not covered by prophylactic antibiotics. Of 957 patients evaluated, 75 were included, with 40 patients (53%) covered by the prophylactic antibiotics received. Multidrug-resistant pathogens were isolated in 23 (58%) patients covered versus 26 (74%) patients not covered (p = 0.128). The median time to positive culture was less in patients not covered by initial antibiotics compared with those who were covered (30.2 vs. 102.1 days; p = 0.003). Over half of the patients developed cultures with pathogens that were covered by their initial antibiotic prophylaxis. (Journal of Surgical Orthopaedic Advances 33(2):084-087, 2024).

指南对开放性骨折的预防性抗菌治疗提出了不同的建议。这项单中心回顾性队列研究旨在确定机构预防性抗生素方案对开放性骨折相关病原体的覆盖程度。作者纳入了有一处或多处开放性骨折且开放性骨折部位培养阳性的成人创伤患者,并比较了使用预防性抗生素的患者与未使用预防性抗生素的患者的治疗效果。在接受评估的 957 名患者中,有 75 名患者接受了预防性抗生素治疗,其中 40 名患者(53%)接受了预防性抗生素治疗。在预防性抗生素覆盖的患者中,有 23 人(58%)分离出了耐多药病原体,而在未覆盖的患者中,有 26 人(74%)分离出了耐多药病原体(P = 0.128)。与使用初始抗生素的患者相比,未使用初始抗生素的患者培养阳性的中位时间较短(30.2 天 vs. 102.1 天;p = 0.003)。半数以上患者培养出的病原体在最初的抗生素预防中已被覆盖。(外科骨科进展杂志》33(2):084-087,2024 年)。
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引用次数: 0
Outcomes of Total Hip Arthroplasty With and Without a History of Hip Arthroscopy. 有无髋关节镜检查史的全髋关节置换术结果
Laura A Stock, Andrea H Johnson, Jane C Brennan, Justin J Turcotte, Benjamin M Petre, Paul J King

Studies have shown increased risk for dislocation, loosening, and revision in patients undergoing total hip arthroplasty (THA) after hip arthroscopy (HA). The authors examined differences in presentation and outcomes between patients who underwent THA with and without prior HA from 2016 to 2021. Twenty-one HA to THA patients were matched on age, sex, race, body mass index (BMI), American Society of Anesthesiology (ASA) score, and comorbidities to 100 THA controls. Univariate analysis was used to determine differences between groups. HA patients were more likely to have Kellgren-Lawrence (KL) grades of 2 or 3, whereas those with no HA were more likely to present with 3 or 4. HA to THA patients had 1.2 mm more joint space than THA patients. Time to THA from first orthopaedic visit was 16 months longer for patients with HA. Postoperatively, there were no significant differences. This suggests THA can be an effective intervention for failed HA. (Journal of Surgical Orthopaedic Advances 33(3):168-170, 2024).

研究表明,髋关节镜(HA)术后接受全髋关节置换术(THA)的患者发生脱位、松动和翻修的风险增加。作者研究了2016年至2021年期间接受全髋关节置换术(THA)和未接受全髋关节置换术的患者在表现和预后方面的差异。根据年龄、性别、种族、体重指数 (BMI)、美国麻醉学会 (ASA) 评分和合并症,将 21 名接受过髋关节置换术的患者与 100 名接受过髋关节置换术的对照组患者进行了配对。采用单变量分析确定组间差异。HA患者的Kellgren-Lawrence(KL)分级更有可能达到2级或3级,而没有HA的患者更有可能达到3级或4级。HA转THA患者的关节间隙比THA患者多1.2毫米。有HA的患者从首次骨科就诊到THA的时间比THA患者长16个月。术后没有明显差异。这表明 THA 可以有效干预失败的 HA。
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引用次数: 0
The Fate of Orthopaedic Surgery Applicants from Medical Schools Without an Orthopaedic Surgery Residency. 没有矫形外科住院医生的医学院的矫形外科申请者的命运。
Joshua R Eskew, Jonathan J Light, Amelia J Weingart, Jacob R Jackowski, Natalie M Marenghi, Lisa Cannada

The purpose of this study was to analyze and assess students from medical schools without a home orthopaedic residency program when applying for a residency position in orthopaedic surgery in terms of metrics utilized by program directors in the Match. An anonymous survey consisting of 23 questions was distributed to graduates of six different medical schools without a home orthopaedic residency program who successfully matched into orthopaedic residency over the past 6 years. Forty-three total responses were received. The number of honors achieved in the junior clerkship phase, mean United States Medical Licensing Examination (USMLE) step 1 and step 2 clinical knowledge (CK) exam scores, number of away rotations, and number of orthopaedic research publications in surgery and total publications overall at the time of application were determined. Graduates of medical schools without a home orthopaedic residency program who successfully matched performed at a higher level across all metrics compared with national match data and the orthopaedic literature. (Journal of Surgical Orthopaedic Advances 33(3):172-177, 2024).

本研究旨在分析和评估来自没有骨科住院医师培训项目的医学院校的学生在申请骨科住院医师职位时,项目主任在匹配中使用的指标。本研究向过去 6 年中成功通过匹配进入骨科住院医师培训的 6 所不同医学院的毕业生发放了一份包含 23 个问题的匿名调查问卷。共收到 43 份回复。调查内容包括初级实习阶段获得的荣誉数量、美国医学执业资格考试(USMLE)第 1 步和第 2 步临床知识考试(CK)的平均分数、外出轮转的次数、申请时在外科领域发表的骨科研究论文数量以及总的论文数量。与全国匹配数据和骨科文献相比,没有骨科住院医师培训项目的医学院毕业生在所有指标上的表现都更优秀。(外科骨科进展杂志》33(3):172-177,2024 年)。
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引用次数: 0
Efficacy of Liposomal Bupivacaine Versus a Traditional Local Anesthetic in Periarticular Injections during Total Hip Arthroplasty: A Systematic Review and Meta-analysis. 在全髋关节置换术中进行关节周围注射时,脂质体布比卡因与传统局麻药的疗效对比:系统回顾与元分析》。
Samantha Harrer, Michael Yayac, Gregory R Toci, Eric Levicoff, P Maxwell Courtney, Andrew M Star, Arjun Saxena

Periarticular injections (PAI) are a common component to multimodal regimens in total hip arthroplasty (THA), although the efficacy of adding liposomal bupivacaine (LB) remains unclear. A meta-analysis of total knee arthroplasty did not find LB superior, but a similar study has not been performed in THA. The purpose of this study was to compare opioid consumption, pain scores, and length of stay between PAIs with LB and traditional PAIs in THA. Eleven included studies showed LB to have minor decreases in opioid consumption and length of stay. No clinically significant benefits were achieved in pain control based on minimal clinically important difference thresholds. There is not adequate evidence to suggest that the increased cost of LB merits its utilization over traditional PAI in THA. The variability in the study designs, as well as results, calls for more consistent randomized clinical trials to ascertain the true efficacy of LB. (Journal of Surgical Orthopaedic Advances 33(3):143-153, 2024).

关节周围注射(PAI)是全髋关节置换术(THA)中多模式疗法的常见组成部分,但加入脂质体布比卡因(LB)的疗效仍不明确。一项关于全膝关节置换术的荟萃分析并未发现 LB 的优越性,但在全髋关节置换术中尚未进行过类似的研究。本研究的目的是比较使用 LB 的 PAI 与传统 PAI 在 THA 中的阿片类药物消耗量、疼痛评分和住院时间。纳入的 11 项研究显示,LB 可略微减少阿片类药物的用量和住院时间。根据最小临床重要性差异阈值,在疼痛控制方面没有取得有临床意义的益处。没有足够的证据表明,在 THA 中使用 LB 比使用传统 PAI 成本增加。由于研究设计和结果存在差异,因此需要更多一致的随机临床试验来确定 LB 的真正疗效。
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引用次数: 0
Who Benefits from Manipulation under Anesthesia Following Total Knee Arthroplasty? 全膝关节置换术后麻醉下操作对哪些人有益?
Matthew L Brown, Kenneth M Vaz, Julie C McCauley, Laura May, Clifford W Colwell

Arthrofibrosis is a multifactorial process that results in decreased knee range of motion (ROM). Manipulation under anesthesia (MUA) is commonly regarded as the preferred initial treatment of arthrofibrosis following total knee arthroplasty (TKA). There have been no well-controlled studies demonstrating that MUA effectively increases ROM in patients who develop arthrofibrosis after TKA when compared with routine care. The purpose of this study was to determine whether MUA had any advantage over routine care in the treatment of patients who developed arthrofibrosis following TKA. The authors identified patients who underwent primary TKA at the authors' institution between 2010 and 2014 and had flexion ≤ 100 degrees at early follow-up. Knees were grouped based on how the arthrofibrosis was treated: those who underwent MUA and those who received routine care. Knee flexion was captured preoperatively (prior to TKA), at early follow-up (prior to MUA or routine care), and at 1-year follow up. Flexion change from early follow-up to 1 year was calculated. The average flexion at 1-year follow-up was not significantly different between the two groups (106.1 ± 11.7 degrees in the routine care group versus 106.3 ± 12.8 degrees in the MUA group). The MUA group had a greater proportion of patients with flexion gains > 20 degrees at final follow-up when compared with patients who underwent routine care (56% vs. 8%, p < 0.0001). This study demonstrates that patients with decreased ROM at early follow-up after primary TKA can expect greater ROM increase at 1-year follow-up if they undergo MUA compared with patients who undergo routine care. (Journal of Surgical Orthopaedic Advances 33(1):033-036, 2024).

关节纤维化是一个多因素过程,会导致膝关节活动范围(ROM)减小。麻醉下手法治疗(MUA)通常被认为是治疗全膝关节置换术(TKA)后关节纤维化的首选初始疗法。与常规治疗相比,目前还没有对照良好的研究证明麻醉下手法治疗能有效增加 TKA 术后关节纤维化患者的活动度。本研究旨在确定 MUA 在治疗 TKA 后出现关节纤维化的患者方面是否比常规护理更具优势。作者确定了2010年至2014年期间在作者所在机构接受初级TKA且早期随访时屈曲度≤100度的患者。根据关节纤维化的治疗方式对膝关节进行分组:接受MUA的患者和接受常规护理的患者。在术前(TKA之前)、早期随访(MUA或常规护理之前)和1年随访时采集膝关节屈曲度。计算从早期随访到 1 年的屈曲变化。两组患者随访1年时的平均屈曲度差异不大(常规护理组为106.1 ± 11.7度,MUA组为106.3 ± 12.8度)。与接受常规护理的患者相比,MUA 组患者在最终随访时屈曲增高大于 20 度的比例更高(56% 对 8% ,P < 0.0001)。这项研究表明,与接受常规治疗的患者相比,接受MUA治疗的患者在初次TKA术后早期随访时的关节活动度下降,而接受MUA治疗的患者在1年随访时的关节活动度有望得到更大的提高。(外科骨科进展杂志》33(1):033-036,2024 年)。
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引用次数: 0
Incidence of Urinary Retention Following Posterior Spinal Fusion for Adolescent and Pediatric Scoliosis at a Single Academic Center: Is There a Role for Prophylactic Tamsulosin? 单个学术中心青少年和儿童脊柱侧凸后路脊柱融合术后尿潴留的发生率:预防性坦索罗辛的作用?
Georges Abdelahad, Alejandro Marquez-Lara, Kathleen Marsh, Alexander Jinnah, John Frino

The purpose of this study is to better characterize patient- and surgery-specific parameters associated with postoperative urinary retention (POUR) and assess the impact of prophylactic Tamsulosin following posterior spinal fusion (PSF) for the management of scoliosis in pediatric and adolescent patients. All patients who underwent PSF for surgical correction of adolescent idiopathic scoliosis (AIS) and neuromuscular scoliosis (NMS) between 2015 and 2019 were retrospectively reviewed. Patients were stratified based on whether they received prophylactic Tamsulosin. Overall, POUR was reported in 3.7% (n = 10) of all patients in the study, although Tamsulosin was associated with a lower rate of POUR, and this did not reach statistical significance. Longer fusion constructs were identified as a risk factor for POUR and could help surgeons counsel families prior to surgery. This is the first study to assess the rate of POUR on AIS and NMS patients following PSF without epidural analgesia. (Journal of Surgical Orthopaedic Advances 33(1):010-013, 2024).

本研究旨在更好地描述与术后尿潴留(POUR)相关的患者和手术特异性参数,并评估在后路脊柱融合术(PSF)治疗儿童和青少年脊柱侧凸后预防性使用坦索罗辛的影响。对2015年至2019年期间接受PSF手术矫正青少年特发性脊柱侧凸(AIS)和神经肌肉性脊柱侧凸(NMS)的所有患者进行了回顾性研究。根据患者是否接受预防性坦索罗辛进行了分层。总体而言,在研究的所有患者中,有3.7%(n = 10)的患者发生了POUR,尽管坦索罗辛与较低的POUR发生率相关,但这并不具有统计学意义。较长的融合结构被认为是POUR的一个风险因素,有助于外科医生在手术前为患者家属提供咨询。这是第一项评估无硬膜外镇痛 PSF 术后 AIS 和 NMS 患者 POUR 发生率的研究。(外科骨科进展杂志》33(1):010-013,2024)。
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引用次数: 0
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Journal of surgical orthopaedic advances
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