Zhonghua shao shang yu chuang mian xiu fu za zhi最新文献

Chronic refractory wounds have emerged as a significant public health challenge that needs to be addressed urgently in China, necessitating strengthened construction of wound repair discipline. Since the National Health Commission of China officially encouraged medical institutions to establish specialized wound repair discipline in 2019, diverse regional models of specialized discipline have emerged nationwide, effectively advancing the construction and development of wound repair discipline system in China. Leveraging Hainan's unique regional characteristics, the First Affiliated Hospital of Hainan Medical University has innovatively integrated the wound repair discipline into the construction of the emergency medical rescue system, successfully creating the distinctive "Hainan Model" for specialized wound repair discipline. This model not only addresses the wound treatment needs of local populations, but also provides robust support for the implementation of national strategic initiatives, achieving dual value in both disciplinary development and social benefits and highlighting its core strengths and advantages. This paper systematically elaborates on the developmental trajectory of Hainan's wound repair system and the exploration of the "Hainan Model" in construction of specialized wound repair discipline, aiming to offer valuable reference for building a China-specific wound repair discipline system and promote its high-quality development.

Wound measurement plays a critical role in wound repair and chronic disease management, its accuracy directly influences the development of personalized treatment plans and the evaluation of wound healing progress. Although traditional one-dimensional measurement methods (such as the ruler method and the probe method) are simple to use, they are unable to meet modern clinical demands due to insufficient accuracy and consistency. In recent years, two-dimensional imaging methods, three-dimensional imaging methods, and the corresponding intelligent measurement devices have become mainstream of wound measurement. By employing digital image processing, three-dimensional modeling, and artificial intelligence technologies, the measurement accuracy has been significantly improved, providing multidimensional data support for the assessment of complex wounds. This article systematically reviews the current development status of wound measurement technologies, representative devices, and their clinical applications. It also explores future directions for optimization, including the integration of artificial intelligence, multi-modal data fusion, and privacy protection. The aim is to provide practical guidance and technical references for clinicians and researchers.

The efficiency of wound repair and the function of regenerated tissue are governed by the precise regulation of the wound microenvironment. At the physiological level, wounds undergo intricate cascades of signaling events, including persistent amplification of inflammation, remodeling of cytokine networks, disruption of redox homeostasis, and succession of microbial communities. The spatiotemporal dynamics of these signals directly determine the course and quality of wound repair. At the physical level, impaired exudate management, compromised microbial barriers, stress concentration at wound edges, and local thermal imbalance further exacerbate tissue injury and delay wound repair. Conventional wound therapies often fail to address the individualized features and dynamic pathological changes of wounds, underscoring the urgent need for a new generation of intelligent dressings capable of real-time sensing pathological signals and adaptive modulation of the wound microenvironment. Natural polysaccharides, characterised by their structural diversity and modifiability, provide a versatile design space for constructing multifunctional hydrogels. The integration of these platforms with exogenous stimulus-responsive platforms further expands the functional potential of wound dressings. This article systematically reviews the latest advances in precise regulation of wound microenvironment by natural polysaccharide hydrogels, focusing on the intelligent response mechanisms to physiological microenvironment and the functional design strategies for physical microenvironment. It aims to provide theoretical guidance for the rational design and clinical application of natural polysaccharide hydrogels.