Pub Date : 2025-09-01Epub Date: 2025-07-01DOI: 10.5624/isd.20250028
Gabass Eltayeb, Ghada Jassem Abdulla, Shamma Karimzadeh, Ahmed Ramadan, Abd Alrahman Alrifai, Maha Albaqali, Basheer Salman, Mohammad S Alrashdan, Shishir Shetty
Purpose: Haller cells (HCs) represent an anatomical variation in the maxillofacial region, frequently linked to sino-nasal pathologies. Numerous regional studies have reported the prevalence of HCs using various imaging modalities. This systematic review aims to evaluate the prevalence of HCs as reported in the existing literature.
Materials and methods: A comprehensive literature search was carried out across multiple databases, including ScienceDirect, PubMed, Scopus, Dentistry and Oral Sciences (EBSCO), Ovid, and LILACS. Different keyword combinations employing Boolean logic were used to identify relevant studies. Data extraction procedures adhered closely to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The quality of studies was assessed using the Critical Appraisal Skills Program (CASP) checklist for cross-sectional studies.
Results: After data extraction, 9 studies qualified for critical analysis. The highest reported prevalence of HCs was 66.84%, whereas the lowest was 16%. Across these 9 studies, the average prevalence was 32.40%. Unilateral HCs predominated in most reported studies. Four studies provided details regarding the shapes of HCs, while size information was available in three studies. Eight of the 9 included studies demonstrated strong evidence quality according to the CASP checklist.
Conclusion: Approximately one-third of radiographic scans analyzed in published studies revealed the presence of HCs. Unilateral HCs were found to be more common than bilateral HCs. The most frequently reported shapes were round, ovoid, and teardrop, with the majority measuring between 2 and 4 mm.
目的:哈勒细胞(HCs)代表了颌面部区域的解剖变异,通常与鼻鼻病变有关。许多区域研究报告了不同成像方式的hcc患病率。本系统综述旨在评估现有文献中报道的hcc患病率。材料和方法:在多个数据库中进行了全面的文献检索,包括ScienceDirect、PubMed、Scopus、Dentistry and Oral Sciences (EBSCO)、Ovid和LILACS。采用布尔逻辑的不同关键词组合来识别相关研究。数据提取程序严格遵守系统评价和荟萃分析(PRISMA)指南的首选报告项目。研究的质量使用关键评估技能程序(CASP)检查表进行横断面研究。结果:数据提取后,9项研究符合关键分析条件。报告的HCs患病率最高为66.84%,最低为16%。在这9项研究中,平均患病率为32.40%。在大多数报道的研究中,单侧hcc占主导地位。4项研究提供了有关hcc形状的详细信息,3项研究提供了hcc的大小信息。9项纳入的研究中有8项根据CASP检查表显示了强有力的证据质量。结论:在已发表的研究中,大约三分之一的x线扫描显示hcc的存在。单侧hcc比双侧hcc更常见。最常见的形状是圆形、卵形和泪滴状,大多数尺寸在2到4毫米之间。
{"title":"Prevalence and radiographic features of Haller cells: A systematic review.","authors":"Gabass Eltayeb, Ghada Jassem Abdulla, Shamma Karimzadeh, Ahmed Ramadan, Abd Alrahman Alrifai, Maha Albaqali, Basheer Salman, Mohammad S Alrashdan, Shishir Shetty","doi":"10.5624/isd.20250028","DOIUrl":"10.5624/isd.20250028","url":null,"abstract":"<p><strong>Purpose: </strong>Haller cells (HCs) represent an anatomical variation in the maxillofacial region, frequently linked to sino-nasal pathologies. Numerous regional studies have reported the prevalence of HCs using various imaging modalities. This systematic review aims to evaluate the prevalence of HCs as reported in the existing literature.</p><p><strong>Materials and methods: </strong>A comprehensive literature search was carried out across multiple databases, including ScienceDirect, PubMed, Scopus, Dentistry and Oral Sciences (EBSCO), Ovid, and LILACS. Different keyword combinations employing Boolean logic were used to identify relevant studies. Data extraction procedures adhered closely to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The quality of studies was assessed using the Critical Appraisal Skills Program (CASP) checklist for cross-sectional studies.</p><p><strong>Results: </strong>After data extraction, 9 studies qualified for critical analysis. The highest reported prevalence of HCs was 66.84%, whereas the lowest was 16%. Across these 9 studies, the average prevalence was 32.40%. Unilateral HCs predominated in most reported studies. Four studies provided details regarding the shapes of HCs, while size information was available in three studies. Eight of the 9 included studies demonstrated strong evidence quality according to the CASP checklist.</p><p><strong>Conclusion: </strong>Approximately one-third of radiographic scans analyzed in published studies revealed the presence of HCs. Unilateral HCs were found to be more common than bilateral HCs. The most frequently reported shapes were round, ovoid, and teardrop, with the majority measuring between 2 and 4 mm.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"55 3","pages":"215-222"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-05-09DOI: 10.5624/isd.20250041
Hyun Jin Cho, Sam-Sun Lee, Joo Hee Kang, Jo-Eun Kim, Kyung-Hoe Huh, Won-Jin Yi, Min-Suk Heo, Han-Gyeol Yeom, Chena Lee, Hang-Moon Choi, Seo-Young An, Jong Seok Lee, Sung Sun Noh, Hyun Jin Kim, Kyung-Hyun Do, Woo Kyoung Jeong, Hong Eo, Hyun Cheol Kim, Jina Shim, Jun-Bong Shin, Jae-Yeon Hwang, Min Woo Lee
Purpose: This study aimed to establish an expert consensus on a set of principles for radiation protection in oral and maxillofacial radiology in Korea. Although national and international guidelines exist, their practical application to dental radiology remains limited, with key clinical components not subject to mandatory enforcement. Therefore, guidelines tailored specifically to dental radiology are necessary to ensure consistent and effective radiation safety.
Materials and methods: A modified Delphi method was utilized, involving 20 experts-7 specialists in oral and maxillofacial radiology and 13 in medical radiology. A Guideline Development Committee initially drafted the principles, which were refined over 3 rounds of email-based surveys. Panelists evaluated each principle using a 9-point Likert scale, with quantitative scores and qualitative feedback informing the revision process.
Results: Consensus was reached on 10 principles, addressing radiographic justification, imaging scope limitations, pregnancy considerations, pediatric optimization, portable radiography, radiation dose monitoring and equipment operation. Final agreement scores approached 9.0, with standard deviations ≤0.7, confirming strong expert consensus.
Conclusion: The finalized principles constitute a structured, evidence-based guideline aligned with international standards while addressing specific challenges unique to oral and maxillofacial radiology. They offer practical strategies to enhance patient safety and standardize radiographic decision-making. Further research should investigate their clinical implementation and recommend periodic updates to reflect evolving technologies.
{"title":"Development of 10 principles of radiation protection in oral and maxillofacial radiology.","authors":"Hyun Jin Cho, Sam-Sun Lee, Joo Hee Kang, Jo-Eun Kim, Kyung-Hoe Huh, Won-Jin Yi, Min-Suk Heo, Han-Gyeol Yeom, Chena Lee, Hang-Moon Choi, Seo-Young An, Jong Seok Lee, Sung Sun Noh, Hyun Jin Kim, Kyung-Hyun Do, Woo Kyoung Jeong, Hong Eo, Hyun Cheol Kim, Jina Shim, Jun-Bong Shin, Jae-Yeon Hwang, Min Woo Lee","doi":"10.5624/isd.20250041","DOIUrl":"10.5624/isd.20250041","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to establish an expert consensus on a set of principles for radiation protection in oral and maxillofacial radiology in Korea. Although national and international guidelines exist, their practical application to dental radiology remains limited, with key clinical components not subject to mandatory enforcement. Therefore, guidelines tailored specifically to dental radiology are necessary to ensure consistent and effective radiation safety.</p><p><strong>Materials and methods: </strong>A modified Delphi method was utilized, involving 20 experts-7 specialists in oral and maxillofacial radiology and 13 in medical radiology. A Guideline Development Committee initially drafted the principles, which were refined over 3 rounds of email-based surveys. Panelists evaluated each principle using a 9-point Likert scale, with quantitative scores and qualitative feedback informing the revision process.</p><p><strong>Results: </strong>Consensus was reached on 10 principles, addressing radiographic justification, imaging scope limitations, pregnancy considerations, pediatric optimization, portable radiography, radiation dose monitoring and equipment operation. Final agreement scores approached 9.0, with standard deviations ≤0.7, confirming strong expert consensus.</p><p><strong>Conclusion: </strong>The finalized principles constitute a structured, evidence-based guideline aligned with international standards while addressing specific challenges unique to oral and maxillofacial radiology. They offer practical strategies to enhance patient safety and standardize radiographic decision-making. Further research should investigate their clinical implementation and recommend periodic updates to reflect evolving technologies.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"55 3","pages":"280-289"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-05-09DOI: 10.5624/isd.20250004
Alice Corrêa Silva-Sousa, Yara Teresinha Corrêa Silva-Sousa, Guilherme Nilson Alves Dos Santos, Sérgio André Lopes Quaresma, Amanda Pelegrin Candemil, Jardel Francisco Mazzi-Chaves, Manoel Damião Sousa-Neto, Hugo Gaêta-Araujo
Purpose: This study aimed to evaluate artefact expression and volumetric distortion of endodontic obturation materials with varying radiopacity in root canal-treated teeth using cone-beam computed tomography (CBCT).
Material and methods: The radiopacity test was performed according to ANSI/ADA standards for AH Plus sealer, Bio-C Sealer, and conventional and bioceramic cones. Upper incisors were selected and instrumented with WaveOne Gold files (45/05). Teeth were individually positioned into empty sockets of a human jaw, and CBCT scans were initially performed (control group). Each tooth was subsequently filled with different combinations of root filling materials. Mean dentin gray values, image noise, and filling material volumes were measured and segmented. Data comparisons among groups were conducted using analysis of variance and the paired t-test (α=0.05).
Results: The conventional cone and AH Plus demonstrated the highest radiopacity. CBCT images exhibited significantly higher mean gray values, noise, and volumetric distortion for groups with conventional cones and AH Plus sealer (P<0.05).
Conclusion: Bioceramic materials, which had lower radiopacity, generated fewer artefacts and less volumetric distortion compared to conventional gutta-percha cones and AH Plus sealer.
{"title":"Enhancing image quality: The role of low-radiopacity bioceramic materials in CBCT scans.","authors":"Alice Corrêa Silva-Sousa, Yara Teresinha Corrêa Silva-Sousa, Guilherme Nilson Alves Dos Santos, Sérgio André Lopes Quaresma, Amanda Pelegrin Candemil, Jardel Francisco Mazzi-Chaves, Manoel Damião Sousa-Neto, Hugo Gaêta-Araujo","doi":"10.5624/isd.20250004","DOIUrl":"10.5624/isd.20250004","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate artefact expression and volumetric distortion of endodontic obturation materials with varying radiopacity in root canal-treated teeth using cone-beam computed tomography (CBCT).</p><p><strong>Material and methods: </strong>The radiopacity test was performed according to ANSI/ADA standards for AH Plus sealer, Bio-C Sealer, and conventional and bioceramic cones. Upper incisors were selected and instrumented with WaveOne Gold files (45/05). Teeth were individually positioned into empty sockets of a human jaw, and CBCT scans were initially performed (control group). Each tooth was subsequently filled with different combinations of root filling materials. Mean dentin gray values, image noise, and filling material volumes were measured and segmented. Data comparisons among groups were conducted using analysis of variance and the paired t-test (α=0.05).</p><p><strong>Results: </strong>The conventional cone and AH Plus demonstrated the highest radiopacity. CBCT images exhibited significantly higher mean gray values, noise, and volumetric distortion for groups with conventional cones and AH Plus sealer (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Bioceramic materials, which had lower radiopacity, generated fewer artefacts and less volumetric distortion compared to conventional gutta-percha cones and AH Plus sealer.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"55 3","pages":"234-244"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-07-01DOI: 10.5624/isd.20250067
Francisco Pessotto Balem, Débora Costa Ruiz, Mariana Quirino Silveira Soares, Deborah Queiroz Freitas, Anne Caroline Oenning
Purpose: This study assessed the effectiveness of an educational video in reducing tongue positioning errors on panoramic radiographs.
Materials and methods: An educational video instructing patients on proper tongue positioning during panoramic radiograph acquisition was sent via WhatsApp (WhatsApp Inc., Menlo Park, CA, USA) at the time of appointment scheduling. Patients were instructed to view the video again before their appointment. Collected data included patients' sex, age, scheduling method, educational background, the necessity for panoramic radiograph retake, and the reason for retake. The frequency of retakes due to tongue positioning errors was compared with retrospective data from patients who did not receive the video, resulting in the evaluation of 1,088 panoramic radiographs. Descriptive data analyses were conducted, and simple and multiple logistic regression models were applied with a significance level of 5%.
Results: Of the 1,088 panoramic radiographs evaluated, 69 displayed tongue positioning errors. Of these, 53 radiographs were from patients without access to the educational video, whereas only 16 were from patients who had received the video (P<0.05). Patients without video access were 2.07 times more likely to exhibit tongue positioning errors than those who had access. The other variables assessed (sex, age, scheduling method, and educational background) did not significantly influence tongue positioning errors (P>0.05).
Conclusion: Providing patients with an educational video on proper tongue positioning significantly reduced tongue positioning errors on panoramic radiographs.
{"title":"Reducing positioning errors in panoramic radiographs: Impact of an educational video on tongue positioning.","authors":"Francisco Pessotto Balem, Débora Costa Ruiz, Mariana Quirino Silveira Soares, Deborah Queiroz Freitas, Anne Caroline Oenning","doi":"10.5624/isd.20250067","DOIUrl":"10.5624/isd.20250067","url":null,"abstract":"<p><strong>Purpose: </strong>This study assessed the effectiveness of an educational video in reducing tongue positioning errors on panoramic radiographs.</p><p><strong>Materials and methods: </strong>An educational video instructing patients on proper tongue positioning during panoramic radiograph acquisition was sent via WhatsApp (WhatsApp Inc., Menlo Park, CA, USA) at the time of appointment scheduling. Patients were instructed to view the video again before their appointment. Collected data included patients' sex, age, scheduling method, educational background, the necessity for panoramic radiograph retake, and the reason for retake. The frequency of retakes due to tongue positioning errors was compared with retrospective data from patients who did not receive the video, resulting in the evaluation of 1,088 panoramic radiographs. Descriptive data analyses were conducted, and simple and multiple logistic regression models were applied with a significance level of 5%.</p><p><strong>Results: </strong>Of the 1,088 panoramic radiographs evaluated, 69 displayed tongue positioning errors. Of these, 53 radiographs were from patients without access to the educational video, whereas only 16 were from patients who had received the video (<i>P</i><0.05). Patients without video access were 2.07 times more likely to exhibit tongue positioning errors than those who had access. The other variables assessed (sex, age, scheduling method, and educational background) did not significantly influence tongue positioning errors (<i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Providing patients with an educational video on proper tongue positioning significantly reduced tongue positioning errors on panoramic radiographs.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"55 3","pages":"302-309"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-07-01DOI: 10.5624/isd.20250045
Parisa Motie, Ali Ashkan, Hossein Mohammad-Rahimi, Sahel Hassanzadeh-Samani, Negar Razzaghi, Mohammad Behnaz, Shahriar Shahab, Saeed Reza Motamadian
Purpose: Classifying cervical vertebral maturation (CVM) stages aids in determining the peak period of growth and in predicting growth rates and patterns. This study aimed to develop a multistage framework for the automated classification of CVM.
Materials and methods: The dataset consisted of 2325 lateral cephalograms. Two orthodontists independently classified these images into 6 categories. One object detection model (Faster RCNN) and 2 classification models (ResNet 101) were implemented using the Python programming language and the PyTorch library. The first classification model divided images into 2 primary groups (CS1-CS3 and CS4-CS6) based on the morphology of the C4 vertebra. The second model subsequently classified each primary group into their respective subcategories. Each classification model was trained and evaluated using a 10-fold cross-validation strategy. The learning process of the models was visualized with gradient-weighted class activation maps.
Results: The overall framework achieved an accuracy of 82.96%. Object detection for region-of-interest extraction reached mAP50 and mAP75 values of 100%. The first classification model demonstrated an accuracy of 99.10% on the hold-out test set. The classifier for CS1-CS3 images showed higher accuracy than the classifier for CS4-CS6 images (86.49% vs. 82.80%).
Conclusion: The accuracy achieved by this fully automated framework was promising.
目的:对颈椎成熟(CVM)分期进行分类,有助于确定生长高峰期,预测生长速度和模式。本研究旨在建立一个多阶段的CVM自动分类框架。材料和方法:数据集包括2325张侧位脑电图。两名正畸医生独立地将这些图像分为6类。使用Python编程语言和PyTorch库实现了一个对象检测模型(Faster RCNN)和两个分类模型(ResNet 101)。第一种分类模型根据C4椎体形态将图像分为2组(CS1-CS3和CS4-CS6)。第二个模型随后将每个主要群体划分为各自的子类别。每个分类模型都使用10倍交叉验证策略进行训练和评估。用梯度加权类激活图将模型的学习过程可视化。结果:整体框架准确率为82.96%。目标检测对感兴趣区域提取的mAP50和mAP75值达到100%。第一个分类模型在hold-out测试集上的准确率为99.10%。CS1-CS3图像分类器的准确率高于CS4-CS6图像分类器(86.49% vs. 82.80%)。结论:该全自动框架的准确性是有希望的。
{"title":"Improving cervical maturation degree classification accuracy using a multi-stage deep learning approach.","authors":"Parisa Motie, Ali Ashkan, Hossein Mohammad-Rahimi, Sahel Hassanzadeh-Samani, Negar Razzaghi, Mohammad Behnaz, Shahriar Shahab, Saeed Reza Motamadian","doi":"10.5624/isd.20250045","DOIUrl":"10.5624/isd.20250045","url":null,"abstract":"<p><strong>Purpose: </strong>Classifying cervical vertebral maturation (CVM) stages aids in determining the peak period of growth and in predicting growth rates and patterns. This study aimed to develop a multistage framework for the automated classification of CVM.</p><p><strong>Materials and methods: </strong>The dataset consisted of 2325 lateral cephalograms. Two orthodontists independently classified these images into 6 categories. One object detection model (Faster RCNN) and 2 classification models (ResNet 101) were implemented using the Python programming language and the PyTorch library. The first classification model divided images into 2 primary groups (CS1-CS3 and CS4-CS6) based on the morphology of the C4 vertebra. The second model subsequently classified each primary group into their respective subcategories. Each classification model was trained and evaluated using a 10-fold cross-validation strategy. The learning process of the models was visualized with gradient-weighted class activation maps.</p><p><strong>Results: </strong>The overall framework achieved an accuracy of 82.96%. Object detection for region-of-interest extraction reached mAP50 and mAP75 values of 100%. The first classification model demonstrated an accuracy of 99.10% on the hold-out test set. The classifier for CS1-CS3 images showed higher accuracy than the classifier for CS4-CS6 images (86.49% vs. 82.80%).</p><p><strong>Conclusion: </strong>The accuracy achieved by this fully automated framework was promising.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"55 3","pages":"290-301"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-07-01DOI: 10.5624/isd.20250015
Thaiza Goncalves Rocha, Raphael Dos Santos Alves Martins Veiga, Eduardo Murad Villoria, Roberto Josè Pessoa de Magalhães Filho, Angelo Maiolino, Sandra Regina Torres, Maria Augusta Visconti
Purpose: This study analyzed cone-beam computed tomography images of 27 patients with multiple myeloma at different disease stages to identify jawbone destruction patterns and assess their associations with clinical data.
Materials and methods: In this cross-sectional study, 2 trained examiners performed standardized, consensus-based image analyses. Lesions were classified into 4 distinct bone destruction patterns: diffuse, multilocular, unilocular, and punched-out. Clinical data were collected from medical records.
Results: The sample included 51.8% male and 48.2% female patients, predominantly between 42 and 60 years old. All cases exhibited diffuse bone destruction affecting both jaws. Multilocular and unilocular patterns were observed in 51.9% and 29.6% of cases, respectively, while no punched-out lesions were identified. The unilocular pattern was significantly associated with cases classified as International Staging System stage I and Durie-Salmon stage IIIA.
Conclusion: Among the studied cases of multiple myeloma, the most frequently observed bone destruction patterns were diffuse and multilocular. The absence of punched-out lesions may be attributable to the use of 3-dimensional imaging. A clear association was identified between the unilocular pattern and disease staging.
{"title":"Cone-beam computed tomography-based analysis of jawbone destruction patterns in multiple myeloma: Associations with clinical data in an observational study.","authors":"Thaiza Goncalves Rocha, Raphael Dos Santos Alves Martins Veiga, Eduardo Murad Villoria, Roberto Josè Pessoa de Magalhães Filho, Angelo Maiolino, Sandra Regina Torres, Maria Augusta Visconti","doi":"10.5624/isd.20250015","DOIUrl":"10.5624/isd.20250015","url":null,"abstract":"<p><strong>Purpose: </strong>This study analyzed cone-beam computed tomography images of 27 patients with multiple myeloma at different disease stages to identify jawbone destruction patterns and assess their associations with clinical data.</p><p><strong>Materials and methods: </strong>In this cross-sectional study, 2 trained examiners performed standardized, consensus-based image analyses. Lesions were classified into 4 distinct bone destruction patterns: diffuse, multilocular, unilocular, and punched-out. Clinical data were collected from medical records.</p><p><strong>Results: </strong>The sample included 51.8% male and 48.2% female patients, predominantly between 42 and 60 years old. All cases exhibited diffuse bone destruction affecting both jaws. Multilocular and unilocular patterns were observed in 51.9% and 29.6% of cases, respectively, while no punched-out lesions were identified. The unilocular pattern was significantly associated with cases classified as International Staging System stage I and Durie-Salmon stage IIIA.</p><p><strong>Conclusion: </strong>Among the studied cases of multiple myeloma, the most frequently observed bone destruction patterns were diffuse and multilocular. The absence of punched-out lesions may be attributable to the use of 3-dimensional imaging. A clear association was identified between the unilocular pattern and disease staging.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"55 3","pages":"253-260"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-07-12DOI: 10.5624/isd.20250018
Tatielly Karine Costa Alves, Bruna Lara França Lima, Ana Clara Gonzaga da Costa Ferreira, Giulio Cesar Moreira Manzi, Franca Arenare Jeunon, Micena Roberta Miranda Alves E Silva, Flávio Ricardo Manzi
Purpose: This study aimed to evaluate the influence of different cone-beam computed tomography (CBCT) image reconstruction parameters (slice thickness, noise filter application and orthogonal plane) on the calculation of bone fractal dimension and, based on those findings, to determine the optimal protocol for this type of assessment.
Materials and methods: The sample consisted of 18 patients who underwent CBCT scans of the mandible and bone densitometry examinations. Four mandibular regions of interest were selected from the scans, with various image reconstruction parameters applied. Fractal dimension was calculated using the box-counting method. Two independent observers performed the evaluations, and all analyses were conducted with a significance level of 5%.
Results: The retromolar triangle and mandibular body regions did not demonstrate statistically significant differences when different tomographic reconstruction parameters were applied (P>0.05). The mandibular base did not display a consistent pattern that could define the influence of these parameters on its evaluation. The symphysis region showed improved performance in fractal analysis when using sagittal plane images with a 1 mm slice thickness.
Conclusion: Operator-dependent parameters inherent to navigation software can influence fractal dimension analysis, with variations depending on the region of interest. The most appropriate parameters for this evaluation were identified as the sagittal plane with a 1 mm slice thickness. Among the regions assessed, the mandibular body was found to be the most suitable for fractal dimension analysis in CBCT.
{"title":"Influence of cone-beam computed tomography reconstruction parameters on bone fractal dimension: A cross-sectional observational study.","authors":"Tatielly Karine Costa Alves, Bruna Lara França Lima, Ana Clara Gonzaga da Costa Ferreira, Giulio Cesar Moreira Manzi, Franca Arenare Jeunon, Micena Roberta Miranda Alves E Silva, Flávio Ricardo Manzi","doi":"10.5624/isd.20250018","DOIUrl":"10.5624/isd.20250018","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the influence of different cone-beam computed tomography (CBCT) image reconstruction parameters (slice thickness, noise filter application and orthogonal plane) on the calculation of bone fractal dimension and, based on those findings, to determine the optimal protocol for this type of assessment.</p><p><strong>Materials and methods: </strong>The sample consisted of 18 patients who underwent CBCT scans of the mandible and bone densitometry examinations. Four mandibular regions of interest were selected from the scans, with various image reconstruction parameters applied. Fractal dimension was calculated using the box-counting method. Two independent observers performed the evaluations, and all analyses were conducted with a significance level of 5%.</p><p><strong>Results: </strong>The retromolar triangle and mandibular body regions did not demonstrate statistically significant differences when different tomographic reconstruction parameters were applied (<i>P</i>>0.05). The mandibular base did not display a consistent pattern that could define the influence of these parameters on its evaluation. The symphysis region showed improved performance in fractal analysis when using sagittal plane images with a 1 mm slice thickness.</p><p><strong>Conclusion: </strong>Operator-dependent parameters inherent to navigation software can influence fractal dimension analysis, with variations depending on the region of interest. The most appropriate parameters for this evaluation were identified as the sagittal plane with a 1 mm slice thickness. Among the regions assessed, the mandibular body was found to be the most suitable for fractal dimension analysis in CBCT.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"55 3","pages":"261-270"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-07-01DOI: 10.5624/isd.20250023
Ali Nazari, Seyed Mohammad Yousef Najafi, Reza Abbasi, Hossein Mohammad-Rahimi, Parisa Motie, Mina Iranparvar Alamdari, Mehdi Hosseinzadeh, Ruben Pauwels, Falk Schwendicke
Purpose: This study was conducted to develop and evaluate a deep learning-based super-resolution approach for enhancing the quality of cone-beam computed tomography (CBCT) images in dentomaxillofacial imaging.
Materials and methods: A deep learning-based super-resolution method using the MIRNet-v2 model was developed to enhance CBCT image quality. The study used a dataset comprising 6,961 anonymized axial slices from 15 CBCT scans. High-resolution images served as ground truth, while low-resolution versions were created through artificial degradation, including downscaling, blurring, and noise addition. The model was evaluated using a 5-fold cross-validation strategy, employing peak signal-to-noise ratio (PSNR) and structural similarity index measure (SSIM) as metrics. Qualitative assessments conducted by 2 experienced radiologists involved criteria such as noise, sharpness, spatial resolution, and diagnostic quality, scored using a CBCT evaluation chart.
Results: The model significantly improved degraded CBCT images across all evaluation metrics. Enhanced images demonstrated mean PSNR values exceeding 35 dB and SSIM values over 0.85, with the highest performance achieved for blurred images (PSNR: 43.86±1.61, SSIM: 0.98±0.01). Subjective assessments indicated improvements in diagnostic quality, noise reduction, and spatial resolution, with outputs comparable to the original images in several degradation scenarios. Interobserver reliability was fair (Cohen kappa: 0.335). Notable improvements were observed for noise and artifact reduction in specific degradation groups, suggesting improved diagnostic utility.
Conclusion: Deep learning-based super-resolution demonstrates considerable potential for enhancing CBCT image quality, especially in scenarios involving blur and downscaling. These results suggest possible applications in low-dose imaging protocols and improved clinical decision-making.
{"title":"Deep learning for dentomaxillofacial cone-beam computed tomography image quality enhancement: A pilot study.","authors":"Ali Nazari, Seyed Mohammad Yousef Najafi, Reza Abbasi, Hossein Mohammad-Rahimi, Parisa Motie, Mina Iranparvar Alamdari, Mehdi Hosseinzadeh, Ruben Pauwels, Falk Schwendicke","doi":"10.5624/isd.20250023","DOIUrl":"10.5624/isd.20250023","url":null,"abstract":"<p><strong>Purpose: </strong>This study was conducted to develop and evaluate a deep learning-based super-resolution approach for enhancing the quality of cone-beam computed tomography (CBCT) images in dentomaxillofacial imaging.</p><p><strong>Materials and methods: </strong>A deep learning-based super-resolution method using the MIRNet-v2 model was developed to enhance CBCT image quality. The study used a dataset comprising 6,961 anonymized axial slices from 15 CBCT scans. High-resolution images served as ground truth, while low-resolution versions were created through artificial degradation, including downscaling, blurring, and noise addition. The model was evaluated using a 5-fold cross-validation strategy, employing peak signal-to-noise ratio (PSNR) and structural similarity index measure (SSIM) as metrics. Qualitative assessments conducted by 2 experienced radiologists involved criteria such as noise, sharpness, spatial resolution, and diagnostic quality, scored using a CBCT evaluation chart.</p><p><strong>Results: </strong>The model significantly improved degraded CBCT images across all evaluation metrics. Enhanced images demonstrated mean PSNR values exceeding 35 dB and SSIM values over 0.85, with the highest performance achieved for blurred images (PSNR: 43.86±1.61, SSIM: 0.98±0.01). Subjective assessments indicated improvements in diagnostic quality, noise reduction, and spatial resolution, with outputs comparable to the original images in several degradation scenarios. Interobserver reliability was fair (Cohen kappa: 0.335). Notable improvements were observed for noise and artifact reduction in specific degradation groups, suggesting improved diagnostic utility.</p><p><strong>Conclusion: </strong>Deep learning-based super-resolution demonstrates considerable potential for enhancing CBCT image quality, especially in scenarios involving blur and downscaling. These results suggest possible applications in low-dose imaging protocols and improved clinical decision-making.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"55 3","pages":"271-279"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: Temporomandibular joint osteoarthritis (TMJOA) is a significant subtype of temporomandibular joint disorders (TMDs). The purpose of this study was to comprehensively summarize the current literature on the use of artificial intelligence (AI) technologies in the diagnosis and management of TMJOA using cone-beam computed tomography (CBCT).
Materials and methods: This systematic review was pre-registered in the PROSPERO database (PROSPERO CRD42024509772). Up to December 2023, research was conducted using Google Scholar, Embase, MEDLINE, and Web of Science databases to identify studies evaluating the use of AI technologies in the management and diagnosis of TMJOA via CBCT. The search strategy included MeSH terms, keywords, and their combinations. Risk of bias was assessed using the ROBINS-I tool.
Results: Out of 2,543 articles retrieved, a total of 9 studies were included in this systematic review. All included studies were observational and employed AI models based on convolutional neural networks, including SVA, SSD, LightGBM, XGBoost, and YOLO. The performance of these models varied, with accuracy ranging from 73.5% to 99% and F1-scores between 0.80 and 0.86. Among these, YOLO demonstrated the highest accuracy for the assessment and diagnosis of TMJOA using CBCT scans.
Conclusion: AI algorithms developed for the automated diagnosis of TMJOA can be utilized by clinicians as decision-support tools. Incorporating diverse input data types, such as electronic medical records, radiomics features, and biomarkers, alongside diagnostic imaging may further increase the diagnostic accuracy for TMDs.
目的:颞下颌关节骨关节炎(TMJOA)是颞下颌关节疾病(TMDs)的一个重要亚型。本研究的目的是全面总结目前关于使用人工智能(AI)技术在锥束计算机断层扫描(CBCT)诊断和管理TMJOA的文献。材料和方法:本系统综述在PROSPERO数据库中预先注册(PROSPERO CRD42024509772)。截至2023年12月,研究使用谷歌Scholar、Embase、MEDLINE和Web of Science数据库进行,以确定通过CBCT评估人工智能技术在TMJOA管理和诊断中的应用的研究。搜索策略包括MeSH术语、关键字及其组合。使用ROBINS-I工具评估偏倚风险。结果:在检索到的2543篇文章中,共有9项研究被纳入本系统综述。所有纳入的研究均为观察性研究,采用基于卷积神经网络的人工智能模型,包括SVA、SSD、LightGBM、XGBoost和YOLO。这些模型的性能各不相同,准确率在73.5%到99%之间,f1得分在0.80到0.86之间。其中,YOLO在使用CBCT评估和诊断TMJOA方面表现出最高的准确性。结论:用于TMJOA自动诊断的人工智能算法可作为临床医生决策支持工具。结合不同的输入数据类型,如电子医疗记录、放射组学特征和生物标记物,以及诊断成像,可以进一步提高tmd的诊断准确性。
{"title":"Application of artificial intelligence in the diagnosis and management of temporomandibular joint osteoarthritis using cone-beam computed tomography: An evidence-based systematic review.","authors":"Utkarsh Yadav, Adit Srivastava, Junaid Ahmed, Raveena Yadav, Ajay Kumar, Amlendu Shekhar","doi":"10.5624/isd.20250077","DOIUrl":"10.5624/isd.20250077","url":null,"abstract":"<p><strong>Purpose: </strong>Temporomandibular joint osteoarthritis (TMJOA) is a significant subtype of temporomandibular joint disorders (TMDs). The purpose of this study was to comprehensively summarize the current literature on the use of artificial intelligence (AI) technologies in the diagnosis and management of TMJOA using cone-beam computed tomography (CBCT).</p><p><strong>Materials and methods: </strong>This systematic review was pre-registered in the PROSPERO database (PROSPERO CRD42024509772). Up to December 2023, research was conducted using Google Scholar, Embase, MEDLINE, and Web of Science databases to identify studies evaluating the use of AI technologies in the management and diagnosis of TMJOA via CBCT. The search strategy included MeSH terms, keywords, and their combinations. Risk of bias was assessed using the ROBINS-I tool.</p><p><strong>Results: </strong>Out of 2,543 articles retrieved, a total of 9 studies were included in this systematic review. All included studies were observational and employed AI models based on convolutional neural networks, including SVA, SSD, LightGBM, XGBoost, and YOLO. The performance of these models varied, with accuracy ranging from 73.5% to 99% and F1-scores between 0.80 and 0.86. Among these, YOLO demonstrated the highest accuracy for the assessment and diagnosis of TMJOA using CBCT scans.</p><p><strong>Conclusion: </strong>AI algorithms developed for the automated diagnosis of TMJOA can be utilized by clinicians as decision-support tools. Incorporating diverse input data types, such as electronic medical records, radiomics features, and biomarkers, alongside diagnostic imaging may further increase the diagnostic accuracy for TMDs.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"55 3","pages":"223-233"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-07-12DOI: 10.5624/isd.20250013
Marco Serafin, Benedetta Baldini, Elisa Boccalari, Francesca Parravicini, Piero Antonio Zecca, Alberto Caprioglio
Purpose: This retrospective study aimed to evaluate the accuracy of facial scan (FS) to cone-beam computed tomography (CBCT) registration by comparing superimpositions on full-cranium and reduced field-of-view (FOV) CBCT, with the goal of assessing its potential to reduce radiation exposure without compromising diagnostic quality.
Materials and methods: CBCT scans from 50 patients were analyzed, integrating FS data obtained via 3D laser scanning. FSs were registered to both full-cranium and reduced FOV CBCT using landmark-based matching and a best-fit algorithm. Accuracy was evaluated by calculating the point-to-point surface distance between FS and CBCT soft-tissue renderings. The metrics used were root mean square distance (RMSD), Hausdorff distance (HD), and median distance (MD). Registration of FS onto full FOV CBCT served as the ground truth. Statistical analysis employed the Mann-Whitney U test to compare registration performance on both the overall surface and the facial midline.
Results: There was no significant difference in HD (P=0.288) between the 2 methods. However, median RMSD and MD were significantly lower for full-cranium CBCT (P=0.019). Midline alignment between FS and reduced FOV CBCT showed no visual discrepancies, with an MD of 0.35 mm along the midsagittal plane.
Conclusion: FS registration to reduced FOV CBCT provides clinically acceptable accuracy, particularly in the midline region, while substantially reducing radiation exposure. This approach is promising for a range of dental applications, especially in pediatric cases and situations prioritizing facial aesthetics. Further research is warranted to optimize this technique for diverse clinical contexts.
{"title":"Accuracy of facial scan registration: A comparison between full-cranium and reduced field-of-view cone-beam computed tomography.","authors":"Marco Serafin, Benedetta Baldini, Elisa Boccalari, Francesca Parravicini, Piero Antonio Zecca, Alberto Caprioglio","doi":"10.5624/isd.20250013","DOIUrl":"10.5624/isd.20250013","url":null,"abstract":"<p><strong>Purpose: </strong>This retrospective study aimed to evaluate the accuracy of facial scan (FS) to cone-beam computed tomography (CBCT) registration by comparing superimpositions on full-cranium and reduced field-of-view (FOV) CBCT, with the goal of assessing its potential to reduce radiation exposure without compromising diagnostic quality.</p><p><strong>Materials and methods: </strong>CBCT scans from 50 patients were analyzed, integrating FS data obtained via 3D laser scanning. FSs were registered to both full-cranium and reduced FOV CBCT using landmark-based matching and a best-fit algorithm. Accuracy was evaluated by calculating the point-to-point surface distance between FS and CBCT soft-tissue renderings. The metrics used were root mean square distance (RMSD), Hausdorff distance (HD), and median distance (MD). Registration of FS onto full FOV CBCT served as the ground truth. Statistical analysis employed the Mann-Whitney U test to compare registration performance on both the overall surface and the facial midline.</p><p><strong>Results: </strong>There was no significant difference in HD (<i>P</i>=0.288) between the 2 methods. However, median RMSD and MD were significantly lower for full-cranium CBCT (<i>P</i>=0.019). Midline alignment between FS and reduced FOV CBCT showed no visual discrepancies, with an MD of 0.35 mm along the midsagittal plane.</p><p><strong>Conclusion: </strong>FS registration to reduced FOV CBCT provides clinically acceptable accuracy, particularly in the midline region, while substantially reducing radiation exposure. This approach is promising for a range of dental applications, especially in pediatric cases and situations prioritizing facial aesthetics. Further research is warranted to optimize this technique for diverse clinical contexts.</p>","PeriodicalId":51714,"journal":{"name":"Imaging Science in Dentistry","volume":"55 3","pages":"245-252"},"PeriodicalIF":2.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}