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Diffusion-Weighted Magnetic Resonance Imaging in the Evaluation of Wilms Tumors: Correlation with Histological Data. Pilot Study 弥散加权磁共振成像对Wilms肿瘤的评价:与组织学资料的相关性。试点研究
IF 2.7 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2021-11-02 DOI: 10.52560/2713-0118-2021-5-28-37
E. E. Manzhurtsevа, V. A. Lopatina, P. Menshchikov, G. Tereshchenko
The aim of the study is to assess the difference in apparent diffusion coefficient (ADC) values depending on the degrees of malignancy of Wilms’ tumor. The study includes 64 patients with verified Wilms tumor after a course of chemotherapy, before undergoing surgical treatment. The patients were examined using scanners with magnetic field induction of 3.0 and 1,5 T. ADC data collection (mm2/s) was carried out using specialized software. Statistical analysis was performed using the Graphpad Prism software package. Based on the results of this study, average ADC values were obtained for histological types of Wilms’ tumors distributed by clinical risk groups: 0.4 × 10-3 mm2/s — for the low grade of malignancy, 1.1 × 10-3 mm2/s — for the average grade of malignancy and 0.6 × 10-3 mm2/s — for the high grade. In addition, for the average grade of malignancy, the ADC values were divided into groups depending on the cellular composition — 1 ± 0.2 × 10-3 mm2/s — for the regressive and mixed type; 0.9 ± 0.2 × 10-3 mm2/s — for the epithelial type; 1.3 ± 0.4 × 10-3 mm2/s — for the stromal type. Thus, diffusion-weighted MRI can be a useful tool in the initial assessment and differential diagnosis of patients with Wilms tumor.
该研究的目的是评估表观扩散系数(ADC)值的差异取决于Wilms肿瘤的恶性程度。该研究包括64例经证实的Wilms肿瘤患者,在接受手术治疗前,经过一个疗程的化疗。采用磁场感应3.0和1.5 t的扫描仪对患者进行检查,采用专用软件进行ADC数据采集(mm2/s)。使用Graphpad Prism软件包进行统计分析。根据本研究结果,获得临床危险组分布的Wilms肿瘤组织学类型的平均ADC值:低恶性分级为0.4 × 10-3 mm2/s,平均恶性分级为1.1 × 10-3 mm2/s,高恶性分级为0.6 × 10-3 mm2/s。此外,对于恶性肿瘤的平均分级,ADC值根据细胞组成分为组- 1±0.2 × 10-3 mm2/s -回归型和混合型;上皮型为0.9±0.2 × 10-3 mm2/s;1.3±0.4 × 10- 3mm2 /s -基质型。因此,弥散加权MRI在Wilms肿瘤患者的初步评估和鉴别诊断中是一个有用的工具。
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引用次数: 0
The Role of Doppler Ultrasound in the Diagnosis of Postnatal Testicular Torsion in Children 多普勒超声在儿童出生后睾丸扭转诊断中的作用
IF 2.7 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2021-11-02 DOI: 10.52560/2713-0118-2021-5-69-81
E. B. Olkhova, S. Y. Borisov, M. V. Topolnik, A. Y. Tagirova, S. V. Zhumasitov, T. V. Mukaseeva
The diagnostic significance of the color Doppler study of testicular blood flow in testicular torsion has been studied for about 40 years, however, the prognostic value of the results obtained is ambiguous, as are the actual imaging capabilities of the technique. Our own experience of 110 observations of testicular torsion in children older than the neonatal period allows us to draw statistically reliable conclusions. Made on equipment premium-class research made it possible to evaluate how visualization intratesticular vascular pattern, and whirpool-sign and submit the primitive model of the actual inversion, explaining the impossibility of rendering whirpool-sign with the greatest tight inversion. The dynamics of testicular blood flow was studied immediately after successful and unsuccessful manual detorsion and in the long term after operative detorsion and orchopexy. The publication contains a brief analysis of the literature and is extensively illustrated.
彩色多普勒研究睾丸血流对睾丸扭转的诊断意义已经研究了大约40年,然而,所获得的结果的预后价值是模糊的,就像该技术的实际成像能力一样。我们对110例大于新生儿期的儿童睾丸扭转的观察经验使我们能够得出统计上可靠的结论。在设备上进行的一流研究,使评价睾丸内血管形态和漩涡征的可视化成为可能,并提交了实际反演的原始模型,解释了以最大的紧密反转呈现漩涡征的不可能。研究了手工扭转成功和不成功后的睾丸血流动态,以及手术扭转和切除后的长期血流动态。该出版物包含对文献的简要分析,并进行了广泛的说明。
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引用次数: 1
Ultrasound in the Diagnosis of Perinatal Ischemic Strokes (Literature Review with Their Own Clinical Observations) 超声在围产期缺血性脑卒中诊断中的应用(文献综述及自身临床观察)
IF 2.7 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2021-11-02 DOI: 10.52560/2713-0118-2021-5-100-114
Yu.K. Bykova, L. Ushakova, E. A. Filippova, A. Sugak, K. Vatolin, V. Bychenko, V. Zubkov, A. Suvorov
The issues of early diagnosis of perinatal arterial stroke (PAII) continue to be discussed in the domestic and foreign literature. Along with MRI, the ultrasound method allows to identify foci of ischemia of different localization and sizes in newborns. During ultrasound, we identified 29 cases of PAIA of different localization in children of different gestational and postnatal age. Analysis of our own and published data showed that up to 32 weeks of gestational development, AII develops in the lenticular-striar basin, and later in the cortical-subcortical region. Diagnostic capabilities of ultrasound in PAII can be significantly expanded by using ultrasound duplex scanning of brain vessels. Our observations showed that the nature of changes in Doppler parameters depends on the localization of the affected vascular basin and on the duration of cerebrovascular disorders
围产期动脉性卒中(PAII)的早期诊断问题在国内外文献中一直被讨论。与MRI一起,超声方法可以识别新生儿不同位置和大小的缺血灶。在超声检查中,我们发现了29例不同胎龄和出生年龄的儿童不同部位的PAIA。我们自己和已发表的数据分析表明,直到妊娠32周,AII在透镜体-纹状体盆地发育,随后在皮质-皮质下区域发育。超声血管双工扫描可显著提高超声对pai的诊断能力。我们的观察表明,多普勒参数变化的性质取决于受影响血管盆地的定位和脑血管疾病的持续时间
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引用次数: 0
Cardiac and Visceral Signs of Connective Tissue Dysplasia in Children with Juvenile Rheumatoid Arthritis According to Ultrasound Examination Data 根据超声检查资料,儿童类风湿关节炎结缔组织发育不良的心脏和内脏征象
IF 2.7 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2021-11-02 DOI: 10.52560/2713-0118-2021-5-91-98
A. Yusufov, I. A. Cherkasova, E. Lavrova, A. A. Plyukhin
To study the cardiac and visceral signs of connective tissue dysplasia in children with juvenile rheumatoid arthritis, a comprehensive ultrasound examination of the abdominal cavity organs and echocardiography examination were conducted according to the standard protocol in 52 children aged from 5 to 16 years with the diagnosis of juvenile rheumatoid arthritis. The reference group consisted of 26 patients with autonomic dysfunction (vegetative-vascular dystonia). The incidence of such visceral dysplasia types as duodenogastric reflux, gastroesophageal reflux, and gallbladder malformations among children with juvenile rheumatoid arthritis was shown higher than in the reference group. The main cardiac sign of connective tissue dysplasia in patients with juvenile rheumatoid arthritis are an excessive chord of the left ventricle.
为研究幼年型类风湿关节炎患儿结缔组织发育不良的心脏及内脏征象,对52例5 ~ 16岁诊断为幼年型类风湿关节炎的患儿按标准方案进行了腹腔器官超声检查及超声心动图检查。参照组由26例自主神经功能障碍(植物性血管张力障碍)患者组成。在幼年类风湿性关节炎儿童中,十二指肠胃反流、胃食管反流和胆囊畸形等内脏发育不良类型的发生率高于对照组。幼年类风湿性关节炎患者结缔组织发育不良的主要心脏征象是左心室弦过长。
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引用次数: 0
Ultrasound Еxamination of the Еxtrahepatic Bile Ducts in Children (Literature Review with our own Clinical Observations) 儿童Еxtrahepatic胆管超声Еxamination检查(文献综述及临床观察)
IF 2.7 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2021-11-02 DOI: 10.52560/2713-0118-2021-5-140-149
A. Yusufov, M. I. Medvedeva, A. A. Plyukhin
To study the normal sonographic anatomy of extrahepatic bile ducts, a polypositional ultrasound examination of 120 children aged 0 to 17 years was conducted. The technique of hepatoduodenal ligament ultrasound examination is described. The main sonographic visual indicators for studying the anatomical and topographic structure of extrahepatic bile ducts in children are denoted. The normative parameters of the common bile and common hepatic ducts in children of different age groups are presented.
为了研究肝外胆管的正常超声解剖,对120例0 ~ 17岁儿童进行了多体位超声检查。介绍肝十二指肠韧带超声检查技术。指出了研究儿童肝外胆管解剖和地形结构的主要超声视觉指标。介绍了不同年龄组儿童胆总管和肝总管的规范性参数。
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引用次数: 0
Radiology Imaging of Bronchiectasis in Children and Adolescents (Literature Review with Own Observations) 儿童和青少年支气管扩张症的影像学表现(附文献综述)
IF 2.7 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2021-11-02 DOI: 10.52560/2713-0118-2021-5-115-128
P. Gavrilov
Timely detection of bronchiectasis in children is of great prognostic value. The importance of modern bronchiectasis in children is due to their possible reversibility over time with effective treatment, as well as a number of significant differences between bronchiectasis in childhood and onset in children, which may reflect different phenotypes of bronchiectasis. In adult patients with bronchiectasis that began in childhood, the pathological process has a more severe and worse prognosis compared to bronchiectasis that began in adulthood. In 2020, the European Respiratory Society proposed a new formulation of the terminal «bronchiectasis» for children and adolescents, now this term refers to an abnormal expansion of the bronchi by computed tomography (CT) of the chest, which, if detected early, can be reversible. CT is the true «gold standard» for confirming bronchiectasis in children and adolescents. This method is included in the minimum set of tests for children and adolescents with suspected bronchiectasis according to the recommendations of the European Respiratory Society. When conducting CT, it is recommended to perform a continuous spiral scan with a collimation of 1 mm, the study is carried out without intravenous use using low-dose protocols. To assess the state of the bronchi in children and adolescents, it is necessary to use the pediatric norms of the broncho-arterial ratio (> 0.8). At the same time, radiation methods are not decisive in establishing the causes of bronchiectasis and only in rare cases can help in establishing bronchiectasis. Dynamic observation of bronchiectasis for children and adolescents is determined individually. Consideration should be given to repeat chest computed tomography scans to answer the question that will change treatment.
及时发现儿童支气管扩张症具有重要的预后价值。现代儿童支气管扩张的重要性在于,随着时间的推移,通过有效的治疗,支气管扩张可能具有可逆性,而且儿童支气管扩张与儿童发病之间存在许多显著差异,这可能反映了支气管扩张的不同表型。在儿童期开始的成人支气管扩张患者中,与成年期开始的支气管扩张相比,其病理过程更严重,预后更差。2020年,欧洲呼吸学会提出了儿童和青少年终末期“支气管扩张”的新说法,现在这个术语是指通过胸部计算机断层扫描(CT)发现的支气管异常扩张,如果早期发现,可以逆转。CT是确认儿童和青少年支气管扩张的真正“金标准”。根据欧洲呼吸学会的建议,该方法包括在疑似支气管扩张的儿童和青少年的最小测试集中。在进行CT时,建议进行连续螺旋扫描,准直为1mm,本研究采用低剂量方案进行,无需静脉注射。为了评估儿童和青少年的支气管状况,有必要使用儿童标准的支气管动脉比(> 0.8)。同时,放射方法在确定支气管扩张的原因方面并不是决定性的,只有在极少数情况下才能帮助确定支气管扩张。儿童和青少年支气管扩张的动态观察是单独确定的。应考虑重复胸部计算机断层扫描,以回答将改变治疗的问题。
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引用次数: 0
Visualization of Lesions of Metaphyses and Epiphyses of Bones in Newborns and Young Children 新生儿和幼儿骨的形而上和骨骺病变的可视化
IF 2.7 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2021-11-02 DOI: 10.52560/2713-0118-2021-5-82-90
N. Sholokhova
The aim of this study was to determine the diagnostic capabilities of various methods of radiological diagnostics for lesions of the metaphyses and epiphyses of bones in newborns and young children.The study involved 108 children in the age group 5 days – 12 months with pathological changes in the pineal gland and bone metaphysis. The possibilities and advantages of standard radiography (СR), ultrasound examination (US) and magnetic resonance imaging (MRI) in the early and differential diagnosis of the osteomyelitis process and epiphyseolysis have been determined. High sensitivity (98 %), specificity (99 %) and accuracy (98 %) for ultrasound and sensitivity (94 %), specificity (89 %) and accuracy (95 %) of MRI in diagnosing osteomyelitis in patients of this age groups. At the same time, the possibilities of standard radiography at the stages of early diagnosis of inflammatory processes in the distal parts of the bones were limited due to a number of factors. The use of diagnostic algorithms greatly facilitates the work of a radiologist and reduces the number of false negative results during the initial treatment of patients.
本研究的目的是确定各种放射诊断方法对新生儿和幼儿骨的形而上学和骨骺病变的诊断能力。该研究涉及108名年龄在5天至12个月之间的儿童,他们在松果体和骨干部有病理变化。标准x线摄影(СR)、超声检查(US)和磁共振成像(MRI)在骨髓炎过程和骨骺溶解的早期和鉴别诊断中的可能性和优势已经确定。超声诊断骨髓炎的敏感性(98%)、特异性(99%)和准确性(98%)高,MRI诊断骨髓炎的敏感性(94%)、特异性(89%)和准确性(95%)高。与此同时,由于许多因素,标准x线摄影在早期诊断骨远端炎症过程的可能性受到限制。诊断算法的使用大大方便了放射科医生的工作,并减少了患者初始治疗期间假阴性结果的数量。
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引用次数: 1
Secondary Iron Overload in Pediatric Hematology: the Priority of Free-Breathing Liver Study at 3.0 T Magnetic Resonance Scanner in Children with Severe Iron Overload 小儿血液学继发性铁超载:3.0 T磁共振扫描对严重铁超载儿童自由呼吸肝脏的优先研究
IF 2.7 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2021-11-02 DOI: 10.52560/2713-0118-2021-5-39-53
E. E. Manzhurtsevа, G. Tereshchenko, D. Kupriyanov, G. Novichkova
The aim of the study was to compare the effectiveness and scanning features of iron detection in the liver based on 3T MR scanner data using a breath holding and free breathing sequences in children with iron overload. 108 patients aged of 3 to 17 years with secondary iron overload associated with the regular blood transfusions underwent an MRI study on a 3.0 T MR scanner using specialized sequences for obtaining relaxometric maps: 3T-mGRE and 3T-uTE. The quality of the images received by the 3T-mGRE and 3T-uTE sequences was assessed by determining the signal-to-noise ratio (SNR). The SNR of 3T-uTE was found to be 8 times higher than the SNR of 3T-mGRE. In addition, it was found that for patients with an iron overload less than 25 mg/g the 3T-mGRE and 3T-uTE sequences showed the same efficacy in iron detection in the liver (r = 0.99, p = 0.54). The concentration of iron in the liver in patients with extremely severe iron overload could be calculated only using 3T-uTE relaxometric maps due to the high approximation error of the results obtaining by 3T-mGRE maps. These data demonstrate the possibility of using the 3T-mGRE sequence to determine the concentration of iron in the liver below 25 mg/g. However, with extremely severe iron overload, it is better to use the 3T-uTE sequence.
该研究的目的是比较铁超载儿童使用屏气和自由呼吸序列基于3T MR扫描仪数据的肝脏铁检测的有效性和扫描特征。108例3 - 17岁的常规输血继发性铁超载患者在3.0 T MR扫描仪上进行了MRI研究,使用专门的序列获得松弛测量图:3T-mGRE和3T-uTE。通过确定信噪比(SNR)来评估3T-mGRE和3T-uTE序列接收到的图像质量。3T-uTE的信噪比是3T-mGRE的8倍。此外,我们还发现,对于铁负荷小于25 mg/g的患者,3T-mGRE和3T-uTE序列在肝脏铁检测中表现出相同的功效(r = 0.99, p = 0.54)。由于3T-mGRE图所得结果的近似误差较大,因此只能使用3T-uTE弛豫图来计算极严重铁过载患者的肝脏铁浓度。这些数据证明了使用3T-mGRE序列测定肝脏中铁浓度低于25 mg/g的可能性。然而,对于极其严重的铁过载,最好使用3T-uTE序列。
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引用次数: 0
Ultrasound Diagnostics of the Kidney Carbuncle (Brief Literature Review and Case Report of the Girl 5 Years Old) 肾痈的超声诊断(文献复习并附5岁女童一例报告)
IF 2.7 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2021-11-02 DOI: 10.52560/2713-0118-2021-5-150-160
E. V. Dmitriyeva, M. Bulanov, V. E. Lykov, T. V. Barhatova
The article presents a case of preoperative diagnostics of a rare variant purulent-inflammatory kidney disease in children – the kidney carbuncle. The rarity of the pathology and the early child’s age (5 years old) determined complexity of clinical diagnostics and the importance of radiation research methods. The diagnosis was suspected by ultrasound diagnostics and confirmed by CT. The child was operated on (resection of the upper pole of the kidney), and clinical recovery was achieved. The article includes illustrative material and a brief review of the literature on this problem.
本文提出了一个病例的术前诊断一种罕见的变异型化脓性炎症性肾脏疾病在儿童-肾结石。罕见的病理和早期儿童的年龄(5岁)决定了临床诊断的复杂性和放射研究方法的重要性。经超声诊断怀疑,CT确诊。患儿行肾上极切除手术,临床恢复。这篇文章包括说明性的材料和关于这个问题的文献的简要回顾。
{"title":"Ultrasound Diagnostics of the Kidney Carbuncle (Brief Literature Review and Case Report of the Girl 5 Years Old)","authors":"E. V. Dmitriyeva, M. Bulanov, V. E. Lykov, T. V. Barhatova","doi":"10.52560/2713-0118-2021-5-150-160","DOIUrl":"https://doi.org/10.52560/2713-0118-2021-5-150-160","url":null,"abstract":"The article presents a case of preoperative diagnostics of a rare variant purulent-inflammatory kidney disease in children – the kidney carbuncle. The rarity of the pathology and the early child’s age (5 years old) determined complexity of clinical diagnostics and the importance of radiation research methods. The diagnosis was suspected by ultrasound diagnostics and confirmed by CT. The child was operated on (resection of the upper pole of the kidney), and clinical recovery was achieved. The article includes illustrative material and a brief review of the literature on this problem.","PeriodicalId":51864,"journal":{"name":"Radiology Research and Practice","volume":"79 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2021-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84088920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential Diagnosis of Anterior Mediastinal Masses in Children (Literature Review with Their Own Clinical Observations) 儿童前纵隔肿块的鉴别诊断(附文献及临床观察)
IF 2.7 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2021-11-02 DOI: 10.52560/2713-0118-2021-5-129-139
N. Kriventsova, G. Tereshchenko
The article is devoted to the description of the X-ray anatomy of the mediastinum, the evolution of the classification of this anatomical region. As well as systematization of radiological signs of the most common formations of the anterior (prevascular) mediastinum in children. Based on these data, a table of the most characteristic radiographic features of various neoplasms of different groups. Reflected basic criteria differential diagnosis of various tumors of the anterior mediastinum.
本文致力于纵隔的x线解剖描述,这一解剖区域的分类的演变。以及对儿童最常见的前纵隔(血管前)形成的影像学征象的系统化。根据这些资料,我们列出了不同组的各种肿瘤的最典型的影像学特征。反映了前纵隔各种肿瘤鉴别诊断的基本标准。
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引用次数: 0
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Radiology Research and Practice
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