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Gastric bypass - 10 years' results. 胃旁路手术 - 10 年来的成果。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.33699/PIS.2024.103.1.19-25
M Čierný, J Ucháľ, A Trávniček

Introduction: Gastric bypass has not gained as much popularity in the Czech Republic as technically simpler restrictive bariatric procedures, frequently with a fading long-term effect. The aim of the presentation is to point out the long-term results after two types of gastric bypasses.

Method: Retrospective analysis of prospectively collected data in an initial set of patients after laparoscopic RYGB (Roux Y gastric bypass) and OAGB/MGB (one anastomosis/mini gastric bypass) performed at Breclav Hospital in 2010-2013. Evaluation based on the BAROS system, according to weight development, comorbidities, psychological aspects, complications and reoperations.

Results: Data available for evaluation are from 32 patients out of a total of 60; the follow-up rate is 53%. The patients are lighter by 34 kg on average (0-64 kg); TBWL (total basic weight loss): 25.7%. The majority of operated diabetics are free of signs of diabetes, and all others have a reduced need for antidiabetic medication. Hypertension, sleep apnea and psychological assessment of life in 6 domains improved. Eight of the 32 followed patients underwent reoperation during 10 years; only 2 of these procedures were acute for complications (anastomotic ulceration), both in smokers; further elective reoperations included 2 conversions of OAGB/MGB to RYGB due to reflux, 2 corrective surgeries, and 2 procedures for a suspected internal hernia. There was no conversion from laparoscopic to open surgery, no peritonitis associated with a leak, and no mortality within 30 days. The BAROS score (5.56) indicates a "very good result" of the gastric bypasses after 10 years.

Conclusion: Gastric bypasses are safe and provide a high and lasting metabolic effect that meets the general expectations of an invasive intervention that can fundamentally improve the quality of treatment for otherwise incurable chronic diseases related to adiposity (so-called ABCD), especially type 2 diabetes.

导言:在捷克共和国,胃旁路术并不像技术上更简单的限制性减肥手术那样广受欢迎,其长期效果往往不明显。本文旨在介绍两种胃旁路术后的长期效果:方法:对2010年至2013年在布雷克拉夫医院接受腹腔镜RYGB(Roux Y胃旁路术)和OAGB/MGB(单吻合/迷你胃旁路术)手术的首批患者的前瞻性数据进行回顾性分析。根据体重发展、合并症、心理方面、并发症和再手术情况,按照 BAROS 系统进行评估:在总共 60 名患者中,有 32 名患者的数据可供评估;随访率为 53%。患者体重平均减轻 34 千克(0-64 千克);TBWL(总基本体重减轻)为 25.7%:25.7%.大多数接受过手术的糖尿病患者都没有了糖尿病的症状,所有其他患者对抗糖尿病药物的需求也有所减少。高血压、睡眠呼吸暂停和生活心理评估等 6 个方面均有所改善。在 32 名接受随访的患者中,有 8 名患者在 10 年间接受了再次手术;其中只有 2 例是因并发症(吻合口溃疡)而进行的急性手术,这 2 例患者都是吸烟者;其他选择性再次手术包括 2 例因反流而从 OAGB/MGB 转为 RYGB 的手术、2 例矫正手术和 2 例疑似内疝的手术。没有人从腹腔镜手术转为开腹手术,没有人因腹腔渗漏引发腹膜炎,也没有人在 30 天内死亡。10 年后,BAROS 评分(5.56)表明胃旁路术的效果 "非常好":胃旁路术是安全的,并能提供较高和持久的新陈代谢效果,符合人们对侵入性干预的普遍期望,可从根本上改善与肥胖有关的慢性疾病(所谓的 ABCD),尤其是 2 型糖尿病的治疗质量。
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引用次数: 0
Surgical treatment of breast precancers - our experience. 乳腺癌前病变的手术治疗--我们的经验。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.48095/ccrvch2024269
I Zedníková, Mach, M Hlaváčková, K Pivovarčíková, T Svoboda

Introduction: Thanks to mammographic screening and the improvement of breast cancer diagnostics, the detection of precancers is also increasing. They are defined as morphological changes of the mammary gland which are more likely to cause cancer. The evaluated precancers are atypical ductal hyperplasia (ADH), lobular carcinoma in situ (LCIS) and radial scar.

Methodology: In the period 1. 1. 2018-31. 12. 2022, we performed 1,302 planned operations for breast disease at the Surgical Clinic of Teaching Hospital Plzeň, of which 30 (2%) were precancer operations. ADH was confirmed 11×, LCIS 8×, and a radical scar 11×. The average age of the patients in all three groups was 56 years (27-85). Precancer was diagnosed 8× only by sonography, 3× by mammography and 19× by a combination of both methods. Subsequently, a puncture biopsy was always completed. We performed 28 tumor excisions with intraoperative biopsy and 2 mastectomies.

Results: In the case of ADH from puncture biopsy, ADH was confirmed intraoperatively 8×, DCIS was diagnosed 2×, and mucinous carcinoma 1×. In LCIS, no tumor was found by intraoperative biopsy 4×, LCIS was confirmed 1×, lobular invasive carcinoma was diagnosed 1×, mastectomy was performed 2× without intraoperative biopsy. In the radial scar, ADH was diagnosed 3×, sclerosing adenosis 6×, DCIS 1×, invasive carcinoma 1×. After the final histological processing of the samples, there was an increase in diagnosed carcinomas. In ADH, DCIS was confirmed 3×, DIC 2×, and mucinous carcinoma 1×. In LCIS, LIC was diagnosed 3×. In the radial scar, DCIS was confirmed 1×, and invasive carcinoma remain 1×. Thus, carcinoma was diagnosed in 11 patients (37%) thanks to the surgical solution. No patient underwent axillary node surgery. All 11 patients subsequently underwent oncological treatment, always a combination of radiotherapy and hormone therapy. All patients are alive, 10 patients are in complete remission of the disease, one with DCIS experienced a local recurrence after 4 years.

Conclusion: Surgical treatment of precancers of the breast makes sense, DCIS or even invasive cancer is often hidden in addition to precancer. Thanks to the surgical solution, the cancer was detected in time.

导言:由于乳房 X 线照相筛查和乳腺癌诊断技术的改进,乳腺癌前病变的检测率也在不断提高。它们被定义为乳腺的形态变化,更有可能导致癌症。已评估的乳腺癌前病变包括非典型导管增生(ADH)、小叶原位癌(LCIS)和放射状瘢痕:在 1.1. 2018-31.12.2022 年,我们在 Plzeň 教学医院外科诊所实施了 1302 例乳腺疾病计划手术,其中 30 例(2%)为癌前病变手术。确诊 ADH 11 例,LCIS 8 例,根治性疤痕 11 例。三组患者的平均年龄为 56 岁(27-85 岁)。仅通过超声波诊断出癌前病变的有 8 例,通过乳腺 X 射线诊断出癌前病变的有 3 例,通过两种方法联合诊断出癌前病变的有 19 例。随后,均进行了穿刺活检。我们进行了 28 例术中活检的肿瘤切除术和 2 例乳房切除术:结果:在穿刺活检发现 ADH 的病例中,术中确诊 ADH 8 例,确诊 DCIS 2 例,确诊粘液癌 1 例。在 LCIS 中,术中活检未发现肿瘤 4 例,确诊 LCIS 1 例,小叶浸润癌 1 例,乳房切除术 2 例,未进行术中活检。在径向瘢痕中,诊断出 ADH 3×,硬化性腺病 6×,DCIS 1×,浸润癌 1×。对样本进行最终组织学处理后,确诊的癌有所增加。在 ADH 中,确诊 DCIS 3×,DIC 2×,粘液癌 1×。在 LCIS 中,确诊 LIC 3 次。在放射状疤痕中,确诊 DCIS 1 次,浸润癌 1 次。因此,有 11 名患者(37%)通过手术确诊为癌。没有患者接受腋窝结节手术。所有 11 名患者随后都接受了肿瘤治疗,始终是放疗和激素治疗相结合。所有患者均健在,10 名患者病情完全缓解,一名 DCIS 患者在 4 年后局部复发:结论:对乳腺癌前病变进行手术治疗是有意义的,DCIS 甚至浸润性癌症往往隐藏在癌前病变之外。多亏了手术治疗,癌症才得以及时发现。
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引用次数: 0
Surgical treatment of breast cancer associated with pregnancy and lactation. 与妊娠和哺乳有关的乳腺癌手术治疗。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.48095/ccrvch2024255
D Pavlišta

This paper provides a brief overview of current information and recommendations for surgical treatment of breast cancer in pregnancy, including three currently controversial areas - indications for breast-conserving surgery in the 1st trimester of pregnancy, indications for sentinel lymph node biopsy and its technique, and fetal monitoring during surgery.

本文简要概述了目前有关妊娠期乳腺癌手术治疗的信息和建议,包括目前存在争议的三个方面--妊娠头三个月保乳手术的适应症、前哨淋巴结活检的适应症及其技术,以及手术过程中的胎儿监护。
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引用次数: 0
Cystic lymphangioma of the lesser omentum in an adult patient. 一名成年患者的小网膜囊性淋巴管瘤。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.33699/PIS.2024.103.6.224-227
M Mišánik, M Smolár, M Grajciar, J Miklušica, G Mičurová

Introduction: Lymphangiomas belong to the group of benign vascular tumors that originate in the lymphatic tissue. Up to 90% of cases manifest in children before the second year of life. In adults, their presence is very rare. In most cases, they are located in the head, neck and axilla. Intra-abdominal lymphangiomas are very rare and represent less than 1% of all cases.

Case report: The authors present the case of a 64-year-old female patient diagnosed with an intra-abdominal cystic lesion following a routine examination. A CT scan of the abdomen confirmed a cystic lesion located in the lesser omentum between the left lobe of the liver and the lesser curvature of the stomach. The patient was scheduled for laparoscopic exstirpation of the lesion. Histological examination confirmed the clinical diagnosis of cystic lymphangioma of the lesser omentum.

Conclusion: The etiopathogenesis of lymphangiomas remains unclear. Despite the fact that they are benign tumors, lymphangiomas tend to have an infiltrative pattern of growth, invading surrounding structures. The majority of cases are asymptomatic and the diagnosis is incidental. The gold standard in treatment remains complete surgical extirpation with microscopically negative margins.

导言淋巴管瘤属于良性血管肿瘤,起源于淋巴组织。高达 90% 的病例在儿童出生后第二年之前出现。成人淋巴管瘤则非常罕见。大多数情况下,淋巴瘤位于头部、颈部和腋窝。腹腔内淋巴管瘤非常罕见,占所有病例的 1%以下:作者介绍了一名 64 岁女性患者的病例,她在例行检查后被诊断为腹腔内囊性病变。腹部 CT 扫描证实,位于肝左叶和胃小弯之间的小网膜上有一个囊性病变。患者被安排在腹腔镜下切除病灶。组织学检查证实了小网膜囊性淋巴管瘤的临床诊断:结论:淋巴管瘤的发病机制尚不清楚。尽管淋巴管瘤是一种良性肿瘤,但它往往呈浸润性生长,并侵犯周围结构。大多数病例没有症状,诊断是偶然的。治疗的金标准仍然是彻底手术切除,显微镜下阴性边缘。
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引用次数: 0
Spigelian hernia. 脊柱疝
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.33699/PIS.2024.103.3.96-99
L Petr, J Honzík, R Sequens

Introduction: Spigelian hernia is a rare type of abdominal wall hernias which are often diagnosed when incarcerated. These hernias typically develop at the crossing point of the arcuate line and lateral portion of rectus abdominis muscle.

Case report: We present the case of a 44-year-old female patient admitted to our surgery unit for a painful lump in her right mesogastrium. Incarcerated atypical hernia in the right mesogastrium was suspected based on completed imaging assessments. Spigelian hernia was confirmed by preoperative findings. Interestingly, the patient applied interferon (multiple sclerosis therapy) at the site of the lump, which is why the diagnosis of lipodystrophy had been considered.

Conclusion: In general, the diagnosis of Spigelian hernia is difficult. From the anatomical point of view the clinical finding is not always specific. The risk of incarceration is relatively high, and thus even clinically silent findings are indicated for surgery.

简介斯皮格尔疝是一种罕见的腹壁疝,通常在嵌顿时被诊断出来。这种疝通常发生在弓形线和腹直肌外侧的交叉点:本病例是一名 44 岁女性患者的病例,她因右腹中部肿块疼痛而入住本院外科。根据已完成的影像学评估,怀疑患者右侧腹中间隙存在嵌顿性非典型疝。术前检查结果证实为斯皮格疝。有趣的是,患者在肿块部位使用了干扰素(多发性硬化症治疗),这也是考虑脂肪营养不良诊断的原因:总的来说,斯皮格疝的诊断比较困难。从解剖学角度来看,临床发现并不总是特异的。疝气嵌顿的风险相对较高,因此即使是临床无症状,也有手术指征。
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引用次数: 0
Summary of the skin substitute revolution - skin coverings in the modern era of healthcare. 皮肤替代品革命摘要--现代医疗保健中的皮肤覆盖物。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.33699/PIS.2024.103.6.202-207
J Bartková, E Horálková, V Barčinová, R Hrušovská

Skin substitutes and covers are crucial across surgical disciplines, promoting interdisciplinary collaboration to meet varied clinical needs. While some medical professionals may encounter these products infrequently in their practice, understanding their properties and applications is paramount to provide optimal patient care. In this overview, we aim to provide healthcare professionals with essential information regarding skin substitutes and covers, equipping them with knowledge to navigate their use effectively across different clinical scenarios and to optimize patient outcomes. The speed of progress in tissue engineering and regenerative medicine is notable, driven by collaborative efforts among scientists, engineers, and clinicians. Technological advancements, increased funding, and a deeper understanding of cellular and molecular processes have accelerated research and development. However, challenges remain, such as achieving vascularization in engineered tissues, addressing immune responses, and ensuring long-term functionality of regenerated organs. Despite these hurdles, the field continues to evolve rapidly, offering hope for transformative medical solutions that may redefine the treatment landscape soon. In this article, we review the current selected commercially available epidermal, dermal, and total skin substitutes for wound healing.

皮肤替代品和覆盖物在外科领域至关重要,可促进跨学科合作,满足不同的临床需求。虽然一些医疗专业人员在实践中可能很少接触到这些产品,但了解它们的特性和应用对于提供最佳的患者护理至关重要。在本综述中,我们旨在为医疗专业人员提供有关皮肤替代品和覆盖物的基本信息,让他们掌握在不同临床情况下有效使用这些产品的知识,并优化患者的治疗效果。在科学家、工程师和临床医生通力合作的推动下,组织工程和再生医学的发展速度令人瞩目。技术进步、资金增加以及对细胞和分子过程的深入了解加速了研究和开发。然而,挑战依然存在,例如实现工程组织的血管化、解决免疫反应以及确保再生器官的长期功能性。尽管存在这些障碍,该领域仍在继续快速发展,为变革性医疗解决方案带来了希望,可能很快就会重新定义治疗领域。在这篇文章中,我们将回顾目前选定的用于伤口愈合的商业化表皮、真皮和全皮肤替代品。
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引用次数: 0
Oligometastatic pancreatic cancer - prognostic factors for oncosurgical individualized therapy. 少转移性胰腺癌-肿瘤手术个体化治疗的预后因素。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.48095/ccrvch2024421
B Mohelníková Duchoňová, H Švébišová, A Langer, P Skalický, J Tesaříková, M Gregořík, M Loveček

Currently, no international consensus includes surgery as part of the standard of metastatic pancreatic ductal adenocarcinoma care. There is weak evidence to support the general introduction of surgical resection in the metastatic pancreatic ductal adenocarcinoma treatment. However, in the rare cases of oligometastatic spread there is increasing evidence that surgical intervention can lead to favourable outcomes. Individualisation of the care and tailored therapy refers not only to targeted treatment but also to the whole complex cancer care, including the indication for surgery. This review summarizes the current status of combined oncosurgical therapy in the multidisciplinary management of oligometastatic pancreatic cancer, together with our own experience, and discusses future perspectives, particularly regarding prognostic and predictive factors that could better predict this group.

目前,国际上尚无共识将手术作为转移性胰腺导管腺癌治疗标准的一部分。在转移性胰腺导管腺癌的治疗中,没有足够的证据支持手术切除。然而,在罕见的少转移性扩散病例中,越来越多的证据表明手术干预可以导致良好的结果。个性化护理和个性化治疗不仅是指有针对性的治疗,而且包括手术指征在内的整个复杂的癌症护理。本文综述了肿瘤外科联合治疗在少转移性胰腺癌多学科治疗中的现状,结合我们自己的经验,并讨论了未来的前景,特别是关于预后和预测因素,可以更好地预测这一群体。
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引用次数: 0
Therapy of bone infection with an antibiotic cement-coated intramedullary nail - preliminary results.
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.33699/PIS.2024.103.5.167-174
M Petráš, D Ira, L Bučka, M Krtička, J Kovařík

Introduction: Antibiotic cement-coated intramedullary nails (ACCINs) are an increasingly popular method in the treatment of FRI (fracture-related infections). FRI is a major challenge that poses a major problem for the treating physician and the health care system, both in terms of cost of therapy, time required, and the complexity of treatment with an uncertain outcome. The aim of our report is to evaluate the results of surgical management using ACCINs in patients with FRI who were treated during a 5-year period at our institution.

Methods: A retrospective evaluation of the results of surgical treatment using ACCINs in patients with FRI treated at the Department of Trauma Surgery, University Hospital Brno and Faculty of Medicine, Masaryk University in Brno in 2018-2022. Based on the exclusion criteria, 5 out of 18 patients were excluded from the study for the following reasons: a follow-up period less than 6 months, chronic immunosuppressive drug therapy, and any oncological or autoimmune disease. Bone infections in the femoral diaphysis, tibial diaphysis and infections in the ankle joint were among the inclusion criteria for the use of ACCINs. The study population consisted of 13 patients (3 women, 10 men); mean age was 48 years and median age was 44 years. Three patients had an infection after osteosynthesis in the femoral diaphysis, 7 patients had an infection in the tibial diaphysis and 3 had an infection in the ankle joint.

Results: In our cohort, bone healing without any clinical and laboratory signs of infection or stable arthrodesis was observed in 7 (54%) patients. In 3 cases (23%), healing proceeded without any signs of infection. In 3 patients (23%), further surgical treatment was required because of fracture nonhealing (n=1) and because of the combination of bone nonhealing and infection (n=2). The overall limb salvage rate was 100%.

Conclusion: The use of ACCINs fulfills the three basic principles of bone infection therapy after thorough debridement: local action of antibiotics, filling of the dead space, and stabilization of the skeleton. ACCINs provide an effective method in the treatment of FRI of the diaphysis of long bones and septic arthritis of the ankle.

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引用次数: 0
Current treatment strategy for proximal humerus fractures.
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.33699/PIS.2024.103.5.147-157
M Kloub, M Doležalová Hrubá, T Zídek

Fractures of the proximal humerus present a unique challenge in orthopedic practice due to the complex anatomy and biomechanical complexity of this region. The spectrum of injuries occurring here ranges from nondisplaced stable fractures to complex displaced fractures or fracture-dislocations. Historically, the treatment of these fractures has been the subject of much debate and treatment modalities have mainly involved a conservative approach, with surgical management being relatively rare. In recent decades, there has been a paradigm shift in the treatment of proximal humerus fractures not only due to advances in surgical techniques, but especially with the development of new types of angular-stable implants and modern total arthroplasties. The development and availability of high-quality imaging techniques have enabled better understanding of the nature of fractures and precise planning of surgical interventions. The main goals of treatment include restoration of function, pain relief and prevention of complications such as prolonged healing or non-healing and avascular necrosis. An individualized approach to each individual patient, considering all factors that affect the final outcome, appears to be essential in the choice of treatment. The aim of this review article is to provide an up-to-date overview of the current concept of treatment of proximal humerus fractures. Trends in nonoperative and operative treatment strategies, indications for each type of treatment, operative techniques, outcomes, and complications associated with each approach are summarized.

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引用次数: 0
Volkmann's ischaemic contracture of the upper extremity - raising a red flag in the setting of developing countries. 沃尔克曼氏上肢缺血性挛缩症--在发展中国家的环境中引起警惕。
Q4 Medicine Pub Date : 2024-01-01 DOI: 10.33699/PIS.2024.103.6.219-223
S Shrestha, P Obruba, V Kunc, V Kunc

Introduction: Volkmann's ischaemic contracture (VIC) is a disabling condition resulting from tissue necrosis due to impaired vascular supply to the limb. Over the years VIC has become rare in developed countries with many different aetiologies described. It was alarming to have high incidence of established VIC in our practice in Nepal. A detailed analysis was conducted to accurately describe this issue.

Methods: We collected 47 cases of VIC over six years and noted the age, sex, district of origin and cause of VIC, duration of injury to presentation, and the grade of VIC. Then we compared these characteristics of VIC of each Nepal province and created a map to show the problematic regions.

Results: Out of 47 patients, 46 could have been prevented by an early treatment. The most common cause was a tight cast in 25 patients (53.19%), followed by unintentionally self-caused VIC by applying tight bandages in 21 patients (44.68%). Most cases came from province 6 (29.78%). Our group included three mild (6.4%), 35 moderate (74.5%) and nine severe (19.1%) cases of VIC. Only 14 cases (29.78%) had a timely fasciotomy in the past.

Conclusion: VIC is an irreversible complication of the compartment syndrome which is an easily preventable condition in the setting of developing countries. Our focus should, therefore, aim at preventing such disastrous conditions as 97.87% of cases we encountered could have been avoided by proper primary care. In the case of Nepal most cases came from province 6 and province 3.

简介沃尔克曼缺血性挛缩症(VIC)是一种因肢体血管供应受损而导致组织坏死的致残性疾病。多年来,VIC 在发达国家已变得十分罕见,并有许多不同的病因描述。在我们尼泊尔的临床实践中,VIC 的高发病率令人震惊。为了准确描述这一问题,我们进行了详细的分析:我们收集了六年来的 47 例 VIC 病例,并记录了患者的年龄、性别、原籍地区和 VIC 病因、从受伤到发病的持续时间以及 VIC 的等级。然后,我们比较了尼泊尔各省 VIC 的这些特征,并绘制了一张地图来显示存在问题的地区:结果:在 47 名患者中,有 46 人本可通过早期治疗加以预防。最常见的原因是石膏过紧,有 25 名患者(占 53.19%),其次是自己无意中使用过紧的绷带造成的 VIC,有 21 名患者(占 44.68%)。大多数病例来自第 6 省(29.78%)。本组病例包括 3 例轻度 VIC(6.4%)、35 例中度 VIC(74.5%)和 9 例重度 VIC(19.1%)。结论:VIC是一种不可逆转的并发症:结论:VIC 是室间隔综合征的一种不可逆转的并发症,在发展中国家很容易预防。因此,我们的重点应放在预防此类灾难性疾病上,因为我们遇到的 97.87% 的病例本可以通过适当的初级保健来避免。在尼泊尔,大多数病例来自第 6 省和第 3 省。
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引用次数: 0
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Rozhledy v Chirurgii
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