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A starry night: a case report of severe liver injury due to a close-range shotgun blast in Argentina. 星光灿烂的夜晚:阿根廷近距离霰弹枪爆炸导致严重肝损伤的病例报告。
Pub Date : 2024-10-21 DOI: 10.20408/jti.2024.0036
Rodrigo Antonio Gasque, José Gabriel Cervantes, Magalí Chahdi Beltrame, Marcelo Enrique Lenz-Virreira, Emilio Gastón Quiñonez

This report presents the case of a 20-year-old man who sustained a severe liver injury from a closerange shotgun blast. A prompt medical intervention, including damage control exploratory laparotomy and surgical debridement, was undertaken due to the extent of liver damage. Despite challenges such as a nondirected biliary fistula and extensive liver parenchymal injury, comprehensive surgical management led to successful treatment. Postoperative complications, including biloma and fungal infection, were managed appropriately, highlighting the importance of vigilant follow-up care. The case underscores the complexity of managing severe liver trauma and emphasizes the evolving role of trauma damage control strategies and minimally invasive procedures in achieving favorable outcomes.

本报告介绍了一名 20 岁男子因近距离霰弹枪爆炸导致严重肝损伤的病例。由于肝损伤程度严重,医生迅速采取了医疗干预措施,包括损伤控制探查性开腹手术和外科清创术。尽管出现了非定向胆道瘘和广泛的肝实质损伤等难题,但全面的手术管理使治疗取得了成功。术后并发症,包括胆汁瘤和真菌感染,都得到了妥善处理,突出了警惕性随访护理的重要性。该病例凸显了处理严重肝创伤的复杂性,并强调了创伤损伤控制策略和微创手术在取得良好疗效方面不断发展的作用。
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引用次数: 0
Purtscher retinopathy following isolated chest compression: a case report. 孤立胸腔挤压后的 Purtscher 视网膜病变:病例报告。
Pub Date : 2024-10-21 DOI: 10.20408/jti.2024.0032
Min Uk Jang, Ho Gil Jung, Youngwoong Kim

This case report describes the case of a 56-year-old man who developed Purtscher retinopathy following compressive chest trauma. During the tertiary survey, the patient was found to have a unilateral partial vision decline despite sustaining only mild rib fractures. The patient was diagnosed with a rare complication of Purtscher retinopathy. At a 2-week follow-up outpatient examination, improved visual acuity was observed. This case highlights the importance of conducting a tertiary survey not only on the directly impacted site, but also comprehensively across all sites, while attentively listening to and addressing the patient's complaints.

本病例报告描述了一名 56 岁男子在胸部外伤后出现 Purtscher 视网膜病变的病例。在三级检查中,患者被发现单侧部分视力下降,尽管只是轻微的肋骨骨折。患者被诊断为罕见的普氏视网膜病变并发症。在两周的门诊随访检查中,观察到视力有所改善。这个病例突出表明,不仅要对直接受影响的部位进行三级调查,还要对所有部位进行全面调查,同时认真倾听并解决患者的主诉。
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引用次数: 0
Acute irreducible anterior shoulder dislocation due to interposition of the subscapularis muscle and the lesser tuberosity: a case report. 肩胛下肌与小结节之间的夹层导致的急性不可恢复性肩关节前脱位:病例报告。
Pub Date : 2024-10-21 DOI: 10.20408/jti.2024.0044
Nazim Sifi, Ahmad Madani, Mahdi Zeghdoud

Efforts to reduce an anterior shoulder dislocation can fail due to numerous mechanical obstructions caused by soft tissue interposition (long head of the biceps, rotator cuff muscles, labrum, musculocutaneous nerve) and/or bony elements (displaced fragment of a greater tuberosity or glenoid fracture, bone impaction such as a Hill-Sachs lesion fixed on the glenoid rim, a bony Bankart lesion). Herein, we report the case of a 35-year-old man who sustained an anterior shoulder fracture-dislocation of his left shoulder after a fall. Despite a postreduction radiological examination that appeared misleadingly reassuring, subtle signs of persistent subluxation raised concerns. A computed tomography (CT) scan revealed subscapularis muscle entrapment along with avulsion of its bony insertion from the lesser tuberosity of the humerus, and a comminuted avulsion fracture of the greater tuberosity of the humerus. The patient underwent surgery using a deltopectoral approach. This involved releasing the entrapped subscapularis muscle and fixing the two fractured fragments. The lesser tuberosity was reduced and secured with two cannulated screws, and the comminuted fragment of the greater tuberosity was reattached using transosseous sutures. At 12-month follow-up, the patient achieved a Constant-Murley score of 85 of 100, with limitation in internal rotation at L3 but no signs of instability or new dislocation episode. This case underscores the importance of confirming shoulder reduction on at least two orthogonal views and paying close attention to the patient's feedback about sensation in their shoulder. Additionally, it highlights the utility of CT or magnetic resonance imaging scans if doubt exists about the integrity of the reduction.

由于软组织(肱二头肌长头、肩袖肌、盂唇、肌皮神经)和/或骨性要素(大结节或盂骨骨折的移位碎片、固定在盂骨缘上的 Hill-Sachs 病变、骨性 Bankart 病变等)造成的众多机械性障碍,减少肩关节前脱位的努力可能会失败。在此,我们报告了一例 35 岁男子的病例,他在一次跌倒后发生了左肩前部骨折-脱位。尽管复位后的放射学检查似乎令人放心,但持续性半脱位的细微迹象还是引起了他的担忧。计算机断层扫描(CT)显示,肩胛下肌卡压,其骨插入部与肱骨小结节撕脱,肱骨大结节粉碎性撕脱骨折。患者接受了胸骨下入路手术。手术包括松解被夹住的肩胛下肌并固定两块骨折碎片。小结节被缩小,并用两枚套管螺钉固定,大结节的粉碎性骨折片用经骨缝合线重新固定。在12个月的随访中,患者的Constant-Murley评分达到85分(满分100分),L3内旋受限,但没有不稳定或新脱位发作的迹象。该病例强调了在至少两个正交切面上确认肩关节复位并密切关注患者对肩部感觉的反馈的重要性。此外,该病例还强调了如果对肩关节复位的完整性存在疑问,CT 或磁共振成像扫描的实用性。
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引用次数: 0
Endoscopic transorbital approach for the removal of a frontal lobe foreign body: a case report. 经眶内镜方法取出额叶异物:病例报告。
Pub Date : 2024-09-25 DOI: 10.20408/jti.2024.0002
Charles Gervais, Conrad Pelletier, Mathieu Laroche, Pascal Lavergne

Low-velocity orbital penetrating injuries may result in an intracranial retained foreign body that requires surgical removal. We describe the endoscopic transorbital removal of a retained umbrella tip in the frontal lobe, which was secondary to trauma to the orbital roof. This technique facilitated the complete removal of the foreign body without causing additional damage to the surrounding tissue. The patient had a successful postoperative recovery. We also discuss the utility of the transorbital neuroendoscopic procedure in managing these traumatic injuries.

低速眼眶穿透伤可能导致颅内异物滞留,需要手术取出。我们描述了经眶内镜取出额叶内滞留的伞尖的手术,该异物继发于眶顶创伤。这项技术有助于彻底清除异物,而不会对周围组织造成额外损伤。患者术后恢复顺利。我们还讨论了经眶神经内窥镜手术在处理此类外伤时的实用性。
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引用次数: 0
Experience of vascular injuries at a military hospital in Korea. 韩国某军事医院血管损伤的经验
Pub Date : 2024-09-01 Epub Date: 2023-05-19 DOI: 10.20408/jti.2022.0041
Doohun Kim, Soyun Nam, Yoon Hyun Lee, Hojun Lee, Hyun Chul Kim

Purpose: Vascular injuries require immediate surgical treatment with standard vascular techniques. We aimed to identify pitfalls in vascular surgery for trauma team optimization and to suggest recommendations for trauma and vascular surgeons.

Methods: We reviewed 28 victims and analyzed the patterns of injuries, methods of repair, and outcomes.

Results: Ten patients had torso injuries, among whom three thoracic aorta injuries were repaired with thoracic endovascular aortic repair, one left hepatic artery pseudoaneurysm with embolization, and two inferior vena cava with venorrhaphy, three iliac arteries with patch angioplasty or embolization, and three common femoral arteries with bypass surgery or arterioplasty. Four patients had upper extremity injuries, among whom one brachial artery and vein was repaired with bypass surgery after temporary intravascular shunt perfusion, two radial arteries were repaired with anastomoses, and one ulnar artery was repaired with ligation. One radial artery under tension was occluded. Fourteen patients had lower extremity injuries, among whom one superficial femoral artery and vein was repaired with bypass and concomitant ligation of the deep femoral artery and vein, three superficial femoral arteries were repaired with bypass (two concomitant femoral veins with bypass or anastomosis), one deep femoral artery with embolization, two popliteal arteries with bypass or anastomosis, four infrapopliteal transected arteries, one arteriovenous fistula with ligation, and one pseudoaneurysm with bypass. However, one superficial femoral artery and all femoral veins were occluded. One leg replantation failed.

Conclusions: There are potential complications of vascular access during resuscitative endovascular balloon occlusion of the aorta procedures. Vascular repair should be performed without tension or spasm. Preservation of the harvested vein in papaverine solution and blood while using a temporary intravascular shunt is a method of eliminating spasms.

目的:血管损伤需要立即用标准血管技术进行手术治疗。我们的目的是找出血管外科在创伤团队优化中的缺陷,并提出创伤和血管外科医生的建议。方法:我们回顾了28例患者,分析了损伤模式、修复方法和结果。结果:躯干损伤10例,其中胸主动脉损伤3例行胸血管内主动脉修复术,左肝动脉假性动脉瘤1例行栓塞术,下腔静脉2例行静脉缝合术,髂动脉3例行补片血管成形术或栓塞术,股总动脉3例行搭桥手术或动脉成形术。4例患者上肢损伤,其中1例行临时血管内分流灌注后行搭桥术修复肱动静脉,2例行桡动脉吻合修复,1例行尺动脉结扎修复。一条桡动脉受压闭塞。下肢损伤14例,其中1例股浅动静脉行搭桥合并股深动静脉结扎修复,3例股浅动脉行搭桥修复(2例股浅静脉合并搭桥或吻合),1例股深动脉栓塞修复,2例腘动脉搭桥或吻合修复,4例股下动脉横切修复,1例动静脉瘘结扎修复,1例股浅动脉结扎修复。还有一个假性动脉瘤。1股浅动脉及全部股静脉闭塞。一条腿再植失败。结论:在复苏性血管内球囊阻断主动脉手术中存在血管通路的潜在并发症。血管修复应在没有紧张或痉挛的情况下进行。在使用临时血管内分流术的同时,将切除的静脉保存在罂粟碱溶液和血液中是一种消除痉挛的方法。
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引用次数: 0
Minimally invasive techniques as adjuncts in low- versus high-lying retained rectal foreign bodies of autoerotic nature in young men: a tailored management algorithm with two contrasting case reports from India. 微创技术作为年轻男性低位与高位自体残留直肠异物的辅助手段:印度两例对比性病例报告的定制管理算法。
Pub Date : 2024-09-01 Epub Date: 2024-09-30 DOI: 10.20408/jti.2024.0003
Shubham Kumar Gupta, Vivek Kumar Katiyar, Sumit Sharma, Shashi Prakash Mishra, Satyanam Kumar Bhartiya

Retained rectal foreign bodies (RFBs) of an autoerotic nature represent an emerging and rare surgical emergency, posing a sensitive challenge for surgeons. RFBs exhibit a wide range of presentations and require varied management approaches, with the choice of treatment modality differing from case to case. Recently, minimally invasive techniques have been employed for the retrieval of RFBs. In 2021, the World Society of Emergency Surgery and the American Association for the Surgery of Trauma released guidelines on anorectal emergencies, highlighting the usefulness of these techniques as adjunctive tools for both diagnosis and ruling out associated complications. In this report, we describe two noteworthy cases of men who presented to the trauma emergency department with foreign bodies lodged in their rectums. We also highlight the potential role of minimally invasive techniques within a "step-up" approach for the management of retained RFBs.

自发性直肠异物(RFB)是一种新出现的罕见外科急症,给外科医生带来了敏感的挑战。直肠异物的表现多种多样,需要不同的处理方法,不同病例选择的治疗方式也不尽相同。最近,微创技术已被用于取出 RFB。2021 年,世界急诊外科协会和美国创伤外科协会发布了肛门直肠急诊指南,强调了这些技术作为诊断和排除相关并发症的辅助工具的作用。在本报告中,我们描述了两例值得注意的男性病例,他们因异物塞入直肠而到创伤急诊科就诊。我们还强调了微创技术在 "阶梯式 "处理滞留异物中的潜在作用。
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引用次数: 0
Delayed diagnosis of proximal ureter injury after a blunt abdominal trauma in Korea: a case report. 韩国腹部钝伤后近端输尿管损伤的延迟诊断:病例报告。
Pub Date : 2024-09-01 Epub Date: 2024-09-03 DOI: 10.20408/jti.2024.0016
Soon Ki Min, Byungchul Yu, Gil Jae Lee, Min A Lee, Yang Bin Jeon, Youngeun Park, Kang Kook Choi, Hyuk Jun Yang

Traumatic ureteral injuries account for fewer than 1% of traumatic urologic injuries, and those caused by blunt trauma are even rarer than those caused by penetrating trauma. The symptoms associated with ureteral injury may be subtle, with or without hematuria, making it difficult to diagnose. We report the case of a 31-year-old man with a delayed diagnosis of proximal ureter injury after abdominal blunt trauma sustained in a motorcycle traffic accident. The patient underwent emergency laparotomy on admission for liver injury, mesenteric injury, and resultant hemoperitoneum. On postoperative day 6, he underwent angioembolization for suspected remnant intra-abdominal bleeding. Persistent symptoms of flank pain and leukocytosis led to follow-up imaging studies that revealed proximal ureter injury, and the patient underwent unilateral nephrectomy. This case stresses the importance of clinical suspicion for genitourinary injuries in the presence of abdominal trauma.

输尿管外伤在泌尿系统外伤中所占比例不到 1%,钝器外伤造成的输尿管外伤比穿透性外伤造成的输尿管外伤更为罕见。输尿管损伤的相关症状可能很隐蔽,伴有或不伴有血尿,因此很难诊断。我们报告了一例因摩托车交通事故造成腹部钝性外伤而导致输尿管近端损伤诊断延迟的 31 岁男性病例。患者入院时因肝脏损伤、肠系膜损伤和腹腔积血接受了急诊开腹手术。术后第 6 天,他因怀疑腹腔内残余出血而接受了血管栓塞术。持续的侧腹疼痛和白细胞增多症状导致后续影像学检查发现输尿管近端损伤,患者接受了单侧肾切除术。本病例强调了临床怀疑腹部创伤时泌尿生殖系统损伤的重要性。
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引用次数: 0
Life-threatening nasotracheal tube obstruction by a blood clot: a case report. 血凝块阻塞鼻气管,危及生命:病例报告。
Pub Date : 2024-09-01 Epub Date: 2024-09-03 DOI: 10.20408/jti.2023.0084
Dajeong Lee, Chan Yong Park, Sang Wha Kim

The nasotracheal tube (NTT) is frequently used in oral and maxillofacial surgery and is generally considered a safe means of protecting the airway while ensuring an adequate surgical field. The most common complication associated with NTT is epistaxis, and only a few cases of foreign body obstruction have been reported. In this case report, the authors aimed to highlight the potential for NTT obstruction following surgery. A 24-year-old female patient, who underwent mandibuloplasty and rhinoplasty at a local clinic, was referred to our hospital patient due to dyspnea and edema on her right mandibular angle. Even with NTT, patient continued to experience mild dyspnea and tachypnea, so a T-piece was applied. However, tachycardia accompanied by a sudden worsening of dyspnea was observed, and bag-valve-mask ventilation was initiated promptly. But oxygen saturation remained unimproved, so an emergency cricothyroidotomy was performed. After 4 hours, the patient's condition stabilized. Upon examination, the previously inserted NTT was identified, and a blood clot approximately 10 cm long at the NTT tip was discovered, causing lumen obstruction. The obstructions of NTT can lead to serious or life-threatening consequences if left unobserved or ignored. Therefore, when a patient with an NTT complains of dyspnea, clinicians should promptly investigate the possibility of partial NTT obstruction to ensure the airway's security.

鼻气管插管(NTT)经常用于口腔颌面外科手术,通常被认为是一种既能保护气道又能确保足够手术视野的安全手段。与 NTT 相关的最常见并发症是鼻衄,而异物阻塞的病例仅有少数报道。在本病例报告中,作者旨在强调手术后出现 NTT 梗阻的可能性。一名 24 岁的女性患者在当地一家诊所接受了下颌角整形术和鼻整形术,因呼吸困难和右下颌角水肿而转诊至我院。即使使用了 NTT,患者仍有轻微的呼吸困难和心动过速,因此使用了 T 片。然而,观察到心动过速并伴有呼吸困难突然加重,于是及时启动了袋阀面罩通气。但血氧饱和度仍未改善,于是紧急进行了环甲膜切开术。4 小时后,患者病情稳定。经检查,发现了之前插入的 NTT,并在 NTT 顶端发现了一个长约 10 厘米的血块,导致管腔阻塞。如果不加以注意或忽视,NTT 阻塞可能会导致严重后果或危及生命。因此,当 NTT 患者主诉呼吸困难时,临床医生应及时检查 NTT 部分阻塞的可能性,以确保气道安全。
{"title":"Life-threatening nasotracheal tube obstruction by a blood clot: a case report.","authors":"Dajeong Lee, Chan Yong Park, Sang Wha Kim","doi":"10.20408/jti.2023.0084","DOIUrl":"10.20408/jti.2023.0084","url":null,"abstract":"<p><p>The nasotracheal tube (NTT) is frequently used in oral and maxillofacial surgery and is generally considered a safe means of protecting the airway while ensuring an adequate surgical field. The most common complication associated with NTT is epistaxis, and only a few cases of foreign body obstruction have been reported. In this case report, the authors aimed to highlight the potential for NTT obstruction following surgery. A 24-year-old female patient, who underwent mandibuloplasty and rhinoplasty at a local clinic, was referred to our hospital patient due to dyspnea and edema on her right mandibular angle. Even with NTT, patient continued to experience mild dyspnea and tachypnea, so a T-piece was applied. However, tachycardia accompanied by a sudden worsening of dyspnea was observed, and bag-valve-mask ventilation was initiated promptly. But oxygen saturation remained unimproved, so an emergency cricothyroidotomy was performed. After 4 hours, the patient's condition stabilized. Upon examination, the previously inserted NTT was identified, and a blood clot approximately 10 cm long at the NTT tip was discovered, causing lumen obstruction. The obstructions of NTT can lead to serious or life-threatening consequences if left unobserved or ignored. Therefore, when a patient with an NTT complains of dyspnea, clinicians should promptly investigate the possibility of partial NTT obstruction to ensure the airway's security.</p>","PeriodicalId":52698,"journal":{"name":"Journal of Trauma and Injury","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic peripheral nerve injuries in young Korean soldiers: a recent 10-year retrospective study. 韩国年轻士兵的外伤性周围神经损伤:最近 10 年的回顾性研究。
Pub Date : 2024-09-01 Epub Date: 2024-08-08 DOI: 10.20408/jti.2024.0001
Chul Jung, Jae-Hyun Yun, Eun Jin Kim, Jaechan Park, Jiwoon Yeom, Kyoung-Eun Kim

Purpose: Traumatic peripheral nerve injury (PNI), which occurs in up to 3% of trauma patients, is a devastating condition that often leads to permanent disability. However, knowledge of traumatic PNI is limited. We describe epidemiology and clinical characteristics of traumatic PNI in Korea and identify the predictors of traumatic complete PNI.

Methods: A list of enlisted soldier patients who were discharged from military service due to PNI over a 10-year period (2012-2021) was obtained, and their medical records were reviewed. Patients were classified according to the causative events (traumatic vs. nontraumatic) and injury severity (complete vs. incomplete). Of traumatic PNIs, we compared the clinical variables between the incomplete and complete PNI groups and identified predictors of complete PNI.

Results: Of the 119 young male patients who were discharged from military service due to PNI, 85 (71.4%) were injured by a traumatic event; among them, 22 (25.9%) were assessed as having a complete injury. The most common PNI mechanism (n=49, 57.6%), was adjacent fractures or dislocations. Several injury-related characteristics were significantly associated with complete PNI: laceration or gunshot wound, PNI involving the median nerve, PNI involving multiple individual nerves (multiple PNI), and concomitant muscular or vascular injuries. After adjusting for other possible predictors, multiple PNI was identified as a significant predictor of a complete PNI (odds ratio, 3.583; P=0.017).

Conclusions: In this study, we analyzed the characteristics of enlisted Korean soldiers discharged due to traumatic PNI and found that the most common injury mechanism was adjacent fracture or dislocation (57.6%). Patients with multiple PNI had a significantly increased risk of complete injury. The results of this study contribute to a better understanding of traumatic PNI, which directly leads to a decline in functioning in patients with trauma.

目的:外伤性周围神经损伤(PNI)发生率高达 3%,是一种破坏性疾病,通常会导致终身残疾。然而,人们对创伤性周围神经损伤的了解还很有限。我们描述了韩国创伤性 PNI 的流行病学和临床特征,并确定了创伤性完全 PNI 的预测因素:我们获得了一份 10 年内(2012-2021 年)因 PNI 而退伍的士兵患者名单,并审查了他们的医疗记录。根据致病事件(创伤性与非创伤性)和损伤严重程度(完全损伤与不完全损伤)对患者进行分类。在创伤性 PNI 中,我们比较了不完全 PNI 组和完全 PNI 组的临床变量,并确定了完全 PNI 的预测因素:结果:在 119 名因 PNI 而退伍的年轻男性患者中,85 人(71.4%)因创伤性事件而受伤;其中 22 人(25.9%)被评估为完全性损伤。最常见的 PNI 机制(49 人,占 57.6%)是邻近骨折或脱位。几种与损伤相关的特征与完全性 PNI 有明显关联:撕裂伤或枪伤、涉及正中神经的 PNI、涉及多条神经的 PNI(多发性 PNI)以及并发的肌肉或血管损伤。在对其他可能的预测因素进行调整后,多发性正中神经损伤被确定为完全性正中神经损伤的重要预测因素(几率比为 3.583;P=0.017):在这项研究中,我们分析了因外伤性 PNI 而退伍的韩国士兵的特征,发现最常见的损伤机制是邻近骨折或脱位(57.6%)。多发性 PNI 患者完全损伤的风险明显增加。本研究的结果有助于更好地了解创伤性 PNI,它直接导致创伤患者功能下降。
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引用次数: 0
Evaluating chemical venous thromboembolism prophylaxis in trauma patients at a single Australian center. 澳大利亚一家中心对创伤患者的化学性静脉血栓栓塞预防措施进行评估。
Pub Date : 2024-09-01 Epub Date: 2024-09-24 DOI: 10.20408/jti.2024.0020
Natalie Quarmby, Minh Tu Vo, Sean Weng Chan

Purpose: Trauma patients are at an elevated risk of developing venous thromboembolism (VTE), with the subsequent mortality in patients requiring intensive care unit admission ranging from 25% to 38%. There remains significant variability in clinical practice related to VTE prophylaxis in trauma patients due to the frequent presence of contraindications impacting the timing and consistency of application. This study aimed to assess the effectiveness of the current practice of chemical VTE prophylaxis in trauma patients at a single Australian center.

Methods: A prospective review was conducted on patients admitted to the ACT Trauma Service (Canberra, Australia) from July to November 2022. The included patients were 18 years or older, without a direct contraindication to anticoagulation, who received chemical VTE prophylaxis with low-molecular-weight heparin (enoxaparin) for at least three doses and underwent subsequent testing of anti-factor Xa (aFXa) levels.

Results: During the study period, 187 patients were admitted, of whom 63 were included in the study. Of these, 47 patients achieved therapeutic levels of anticoagulation as determined by their aFXa levels, while 16 were subtherapeutic. The only statistically significant difference between the two groups was in weight, with patients in the subtherapeutic group weighing an average of 91.9 kg compared to 79.1 kg in the therapeutic group (P<0.05).

Conclusions: A fixed-dose enoxaparin regimen was utilized, with limited individualization based on patient factors, such as injuries, comorbidities, and other biological factors. Sixteen patients (25%) had subtherapeutic VTE prophylaxis, as measured by aFXa levels. Higher weight was significantly correlated with inadequate VTE prophylaxis dosing. While age, sex, and smoking status might play important roles in clinical decision-making, weight-based dosing of low-molecular-weight heparin may be more effective in achieving adequate VTE prophylaxis.

目的:创伤患者罹患静脉血栓栓塞症(VTE)的风险较高,需要入住重症监护室的患者死亡率为 25% 至 38%。由于经常出现的禁忌症影响了用药的时间和一致性,因此在创伤患者的 VTE 预防临床实践中仍存在很大的差异。本研究旨在评估澳大利亚一家中心目前对创伤患者进行化学性 VTE 预防的有效性:方法:对澳大利亚首都地区创伤服务中心(澳大利亚堪培拉)2022 年 7 月至 11 月期间收治的患者进行了前瞻性回顾。纳入的患者年龄在18岁或18岁以上,无直接抗凝禁忌症,接受了至少三次低分子量肝素(依诺肝素)化学VTE预防治疗,并接受了后续的抗因子Xa(aFXa)水平检测:研究期间共收治了 187 名患者,其中 63 人被纳入研究。其中,47 名患者的 aFXa 水平达到了抗凝治疗水平,16 名患者处于治疗水平以下。两组患者在体重上的差异唯一具有统计学意义,亚治疗组患者的平均体重为 91.9 千克,而治疗组患者的平均体重为 79.1 千克(PConclusions:采用了固定剂量的依诺肝素治疗方案,但根据患者伤情、合并症和其他生物因素等因素进行的个性化治疗有限。根据 aFXa 水平,16 名患者(25%)的 VTE 预防治疗效果不佳。较高的体重与 VTE 预防剂量不足明显相关。虽然年龄、性别和吸烟状况在临床决策中可能起着重要作用,但基于体重的低分子量肝素剂量可能更能有效实现充分的 VTE 预防。
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引用次数: 0
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Journal of Trauma and Injury
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