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Comments on "Endoscopic transorbital approach for the removal of a frontal lobe foreign body: a case report". “内镜下经眶入路切除额叶异物1例”评论。
IF 0.2 Pub Date : 2025-11-20 DOI: 10.20408/jti.2025.0131
Myoung Soo Kim
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引用次数: 0
Self-inflicted rectal injury triggering acute myocardial infarction: a case report. 自残直肠损伤引发急性心肌梗死1例。
IF 0.2 Pub Date : 2025-11-20 DOI: 10.20408/jti.2025.0138
Muge Gulen, Mehmet Gorur, Salim Satar, Selen Acehan, Ozge Ozcan Abacioglu, Adnan Kuvvetli

A 47-year-old male patient who had self-inserted a rectal foreign body for anal autoerotic purposes was admitted to the emergency department. Thirty minutes after admission, he developed chest pain and profuse sweating. Electrocardiography revealed an acute inferior myocardial infarction. Initially, the patient underwent coronary angiography, and percutaneous transluminal angioplasty was performed for a 100% occlusion of the right coronary artery. Subsequently, under general anesthesia, the foreign body was removed via rectal examination in the lithotomy position. This rare clinical scenario, which has not been previously reported in the literature, highlights the potential for psychological trauma and local rectal injury to act as triggers for myocardial infarction. Respecting patient confidentiality, maintaining a nonjudgmental approach, and implementing a multidisciplinary strategy are critically important for the effective management of such uncommon cases.

一位47岁的男性患者因自我插入直肠异物以达到肛交目的而被送入急诊科。入院30分钟后,患者出现胸痛和大量出汗。心电图显示急性下壁心肌梗死。最初,患者接受了冠状动脉造影,并进行了经皮腔内血管成形术,以100%闭塞右冠状动脉。随后全麻下,取取取石位,经直肠检查取出异物。这种罕见的临床情况,以前从未在文献中报道过,强调了心理创伤和局部直肠损伤作为心肌梗死触发因素的可能性。尊重患者的隐私,保持非判断性的方法,并实施多学科的策略对有效管理这类罕见病例至关重要。
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引用次数: 0
An exsanguinating arterial-vesical injury after a gunshot wound to the lower extremity: a case report. 下肢枪伤后出血的动脉-膀胱损伤:一例报告。
IF 0.2 Pub Date : 2025-11-20 DOI: 10.20408/jti.2025.0046
Brendan P Stewart, Herbert Downton Ramos, Andrew R Doben, Stephanie C Montgomery

Arterial-vesical injuries are rare entities, often presenting with bladder distension, bright red hematuria, and clot retention. The few cases reported in the literature typically occur following traumatic injuries to the groin or pelvis. We present a case of an arterial and vesical injury with decompression through the bladder. Our patient was a 21-year-old man who presented to a level I trauma center as a high-level activation trauma case following a single gunshot wound to the left lateral thigh. Upon arrival, the patient's systolic blood pressure was 80/50 mmHg. A pelvic x-ray revealed ballistic fragments in the pelvis. Physical examination showed a 1+ palpable left dorsalis pedis pulse. He underwent a formal trauma laparotomy, which did not identify any acute injuries. Concurrently, his Foley catheter exhibited bloody output with bladder distension. Following continuous bladder irrigation, he had profuse sanguineous output. Angiography revealed a complete disruption of the profunda femoris artery. An open exploration of the femoral canal was performed to achieve proximal control of the common femoral artery. We identified a 3-cm longitudinal injury to the profunda femoris artery and an obliterated femoral vein, both of which were ligated, resulting in decreased bladder exsanguination and hemodynamic stabilization. Consistent with the limited published cases of arterial-vesical fistula, our patient presented after a traumatic groin injury. Maintaining a high index of suspicion for communication between the thigh and extraperitoneal space due to projectile trajectory remains crucial to successfully managing these challenging injuries.

动脉-膀胱损伤是罕见的,通常表现为膀胱膨胀、鲜红色血尿和血块潴留。文献中报道的少数病例通常发生在腹股沟或骨盆外伤后。我们提出一个病例动脉和膀胱损伤减压通过膀胱。我们的病人是一名21岁的男性,他在左大腿外侧中了一枪后作为高度激活性创伤来到了一级创伤中心。到达时,患者收缩压为80/50 mmHg。骨盆x光片显示骨盆有弹道碎片。体格检查显示左足背脉搏1+可触。他接受了正式的创伤性剖腹手术,没有发现任何急性损伤。同时,他的Foley导尿管显示出血性膀胱膨胀。持续膀胱冲洗后,患者大量出血。血管造影显示股深动脉完全断裂。开放股管探查以达到股总动脉近端控制。我们发现股深动脉和股静脉有一个3厘米的纵向损伤,这两条静脉都被结扎,导致膀胱出血减少和血流动力学稳定。与有限发表的动脉膀胱瘘病例一致,我们的病人是在创伤性腹股沟损伤后出现的。由于弹丸轨迹,保持大腿和腹腔外空间之间的高度怀疑指数对于成功处理这些具有挑战性的损伤至关重要。
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引用次数: 0
Damage control thoracotomy with chest packing for hemorrhage control in massive hemothorax and shock: a case report. 损伤控制开胸胸填塞术治疗大量血胸及休克后出血1例。
IF 0.2 Pub Date : 2025-09-29 DOI: 10.20408/jti.2025.0066
Shivinder Singh, Jitendra Kumar Singh, Shalendra Singh, Aishwainee Vg, Umesh Kumar, Venkat Narayanan

Severe hemorrhagic shock is a leading cause of death among potentially salvageable casualties. We report the case of a 24-year-old man who sustained a gunshot wound to the right hemithorax and presented with class IV hemorrhagic shock. He underwent resuscitative damage control via a right posterolateral thoracotomy. Intraoperatively, the bleeding source was identified as a lacerated posterior intercostal artery at the level of the 11th dorsal vertebra. Because access to the bleeding site remained limited even after extending the incision, right thoracic packing was performed to control the hemorrhage. On reevaluation 48 hours later, no active bleeding was observed.

严重失血性休克是潜在可抢救伤员的主要死因。我们报告的情况下,一个24岁的男子谁持续枪伤到右半胸,并提出了四级失血性休克。他通过右后外侧开胸手术进行了恢复性损伤控制。术中,出血源被确定为在第11背椎水平的后肋间动脉撕裂。由于即使在扩大切口后进入出血部位仍然有限,因此进行右胸填塞以控制出血。48小时后复查,未见活动性出血。
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引用次数: 0
Penetrating orbital floor injury by an undetected foreign body: a case report. 未发现异物穿透眶底损伤1例。
IF 0.2 Pub Date : 2025-09-03 DOI: 10.20408/jti.2025.0025
Simon Chummar, Yamini Ghatikar, K Thoi Thoi Singha, Divya Ann Mathews

Orbital trauma can result in significant complications, particularly when accompanied by foreign body entrapment. Wooden foreign bodies are rare but carry a high risk of infection and chronic inflammation. In these cases, immediate surgical intervention is critical for restoring orbital anatomy and preventing complications. A 16-year-old male patient presented with a 2-month history of persistent pus discharge from his right cheek following facial trauma sustained from a fall. Initial management involved drainage of the abscess; however, the condition persisted. On examination, the patient exhibited infraorbital nerve paresthesia and an orbital floor fracture, and his history was notable for prior foreign body retrieval involving wooden fragments. Computed tomography revealed retained foreign bodies and discontinuity of the orbital floor. Surgical management included foreign body retrieval, the Caldwell-Luc procedure, and orbital floor reconstruction with mesh and platelet-rich fibrin placement. The patient's symptoms progressively improved over 6 months, with a reduction in paresthesia and no ocular or intracranial complications despite the delayed presentation. This case highlights the challenges of diagnosing and managing penetrating wooden foreign bodies in orbital trauma. It underscores the importance of prompt surgical intervention and interdisciplinary care to prevent potentially critical complications.

眶外伤可导致严重的并发症,特别是当伴有异物夹持时。木质异物很少见,但感染和慢性炎症的风险很高。在这种情况下,立即手术干预对于恢复眼窝解剖结构和防止并发症至关重要。一名16岁男性患者,因跌倒造成面部创伤,右脸颊持续流脓2个月。最初的治疗包括脓肿引流;然而,这种情况仍然存在。在检查中,患者表现出眶下神经感觉异常和眶底骨折,他的历史是值得注意的先前异物取出涉及木制碎片。计算机断层扫描显示保留的异物和眶底不连续性。外科治疗包括异物取出,Caldwell-Luc手术,眶底重建与补片和富血小板纤维蛋白放置。患者的症状在6个月内逐渐改善,感觉异常减少,尽管出现延迟,但没有眼部或颅内并发症。本病例强调了在眼眶外伤中诊断和处理穿透性木质异物所面临的挑战。它强调了及时手术干预和跨学科护理的重要性,以防止潜在的严重并发症。
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引用次数: 0
Management of posttraumatic refractory paroxysmal sympathetic hyperactivity with bromocriptine: a case report. 溴隐亭治疗创伤后难治性阵发性交感神经亢进1例。
IF 0.2 Pub Date : 2025-09-03 DOI: 10.20408/jti.2025.0016
Min-Seok Woo, Seong-Hyun Park, Jeong-Hyun Hwang, Chaejin Lee

This case report describes a unique instance of refractory paroxysmal sympathetic hyperactivity (PSH) in a 19-year-old woman following a traumatic brain injury sustained in a motorcycle accident. The patient presented in a semicomatose state with a Glasgow Coma Scale score of 3 (E1, VT, M2), a significant left frontotemporal subdural hematoma, and a midline shift that necessitated emergency craniectomy and hematoma evacuation. Postoperatively, she developed recurrent episodes of hyperthermia, tachycardia, hypertension, tachypnea, diaphoresis, rigidity, and eyeball deviation triggered by non-noxious stimuli. These episodes proved resistant to conventional treatments, including opioids, sedatives, and β-blockers. Based on the clinical presentation and a Paroxysmal Sympathetic Hyperactivity-Assessment Measure score of 28 (out of 29), a diagnosis of PSH was established. Bromocriptine was initiated at 0.025 mg/kg every 12 hours and later increased to every 8 hours, leading to a significant reduction in both the frequency and severity of episodes within days. Complete resolution of PSH episodes was observed by the sixth day of bromocriptine treatment, with no recurrence during the remaining treatment period. Bromocriptine was administered for a total of 1 month before being discontinued, and the patient remained symptom-free over a 10-month follow-up period. This case highlights the efficacy of bromocriptine in managing refractory PSH and underscores the importance of early recognition and targeted intervention for this rare but debilitating condition. Bromocriptine may offer a valuable therapeutic option for similar cases, particularly when conventional therapies fail.

本病例报告描述了一个难治性阵发性交感神经亢进(PSH)的独特实例,发生在一名19岁的女性在摩托车事故中遭受创伤性脑损伤后。患者表现为半昏迷状态,格拉斯哥昏迷评分为3分(E1, VT, M2),左侧额颞叶硬膜下血肿明显,中线移位,需要紧急开颅和血肿清除。术后,患者出现非有害刺激引发的反复高热、心动过速、高血压、呼吸急促、出汗、僵硬和眼球偏离。事实证明,这些发作对包括阿片类药物、镇静剂和β受体阻滞剂在内的常规治疗具有耐药性。根据临床表现和阵发性交感神经亢进评估量表得分28分(总分29分),诊断为PSH。溴隐亭开始剂量为每12小时0.025 mg/kg,后来增加到每8小时一次,导致数天内发作频率和严重程度显著降低。经溴隐亭治疗第6天,PSH发作完全消退,其余治疗期间无复发。在停药前给予溴隐亭共1个月,患者在10个月的随访期间无症状。本病例强调了溴隐亭治疗难治性PSH的疗效,并强调了早期识别和有针对性干预这种罕见但使人衰弱的疾病的重要性。溴隐亭可能为类似病例提供有价值的治疗选择,特别是当常规治疗失败时。
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引用次数: 0
Identification of predictive factors and development of a prediction model for rehabilitation facility discharge in patients with traumatic spinal cord injury: a retrospective analysis of the National Trauma Data Bank. 外伤性脊髓损伤患者出院的预测因素识别和预测模型的建立:对国家创伤数据库的回顾性分析。
IF 0.2 Pub Date : 2025-09-01 Epub Date: 2025-09-29 DOI: 10.20408/jti.2025.0049
James Bridges, Norris C Talbot, Michael Folse, Stephen Whipple, Bharat Guthikonda, Navdeep Samra, Deepak Kumbhare

Purpose: Previous studies have shown that early rehabilitation is associated with better long-term outcomes in patients with traumatic spinal cord injury. However, data are still limited regarding which factors are associated with discharge to a rehabilitation facility. This study aims to expand on prior research by identifying factors associated with disposition and by introducing a prediction model for these factors.

Methods: The National Trauma Data Bank was queried for patients aged 18 years or older who presented to US trauma centers from 2019 to 2021 with traumatic spinal cord injury. Multivariate logistic regression models were used to determine which patient, injury, and hospital variables were significant factors for disposition to a rehabilitation facility, compared to home and intermediate care facilities. Prediction modeling was then performed using these factors.

Results: Overall, 14,597 patients were identified, of whom 6,220 were discharged to a rehabilitation facility, 2,647 to an intermediate care facility, and 5,730 to home. Significant factors associated with discharge to a rehabilitation facility compared to home included age, injury location and severity, insurance type, estimated length of stay, systolic blood pressure at admission, and admission blood alcohol level and drug screen results. Similarly, when comparing discharge to a rehabilitation facility with discharge to an intermediate care facility, sex, age, race, estimated length of stay, systolic blood pressure at admission, drug screen results, and coexisting substance use and metabolic conditions all significantly influenced disposition. Fine tree binary classification achieved a prediction accuracy of 72.5% when comparing discharge to a rehabilitation facility and home, and a prediction accuracy of 70.0% when comparing discharge to a rehabilitation facility and an intermediate care facility.

Conclusions: This study demonstrates significant factors associated with discharge to a rehabilitation facility in patients with traumatic spinal cord injury. Further studies are needed to improve prediction accuracy.

目的:以往的研究表明,早期康复与创伤性脊髓损伤患者较好的长期预后相关。然而,关于哪些因素与出院到康复机构有关的数据仍然有限。本研究旨在通过识别与性格相关的因素并引入这些因素的预测模型来扩展先前的研究。方法:对2019年至2021年在美国创伤中心就诊的18岁及以上的创伤性脊髓损伤患者进行国家创伤数据库的查询。使用多变量logistic回归模型来确定与家庭和中间护理机构相比,哪些患者、损伤和医院变量是选择康复机构的重要因素。然后利用这些因素进行预测建模。结果:总体而言,确定了14,597例患者,其中6,220例出院到康复机构,2,647例出院到中间护理机构,5,730例出院回家。与在家相比,与出院到康复机构相关的重要因素包括年龄、受伤部位和严重程度、保险类型、预计住院时间、入院时收缩压、入院时血液酒精水平和药物筛查结果。同样,当比较出院到康复机构和出院到中间护理机构时,性别、年龄、种族、估计住院时间、入院时收缩压、药物筛选结果、共存的物质使用和代谢状况都显著影响处置。细树二分类在比较康复机构和家庭出院时的预测准确率为72.5%,在比较康复机构和中间护理机构出院时的预测准确率为70.0%。结论:本研究证明了创伤性脊髓损伤患者出院到康复机构的显著因素。需要进一步的研究来提高预测的准确性。
{"title":"Identification of predictive factors and development of a prediction model for rehabilitation facility discharge in patients with traumatic spinal cord injury: a retrospective analysis of the National Trauma Data Bank.","authors":"James Bridges, Norris C Talbot, Michael Folse, Stephen Whipple, Bharat Guthikonda, Navdeep Samra, Deepak Kumbhare","doi":"10.20408/jti.2025.0049","DOIUrl":"10.20408/jti.2025.0049","url":null,"abstract":"<p><strong>Purpose: </strong>Previous studies have shown that early rehabilitation is associated with better long-term outcomes in patients with traumatic spinal cord injury. However, data are still limited regarding which factors are associated with discharge to a rehabilitation facility. This study aims to expand on prior research by identifying factors associated with disposition and by introducing a prediction model for these factors.</p><p><strong>Methods: </strong>The National Trauma Data Bank was queried for patients aged 18 years or older who presented to US trauma centers from 2019 to 2021 with traumatic spinal cord injury. Multivariate logistic regression models were used to determine which patient, injury, and hospital variables were significant factors for disposition to a rehabilitation facility, compared to home and intermediate care facilities. Prediction modeling was then performed using these factors.</p><p><strong>Results: </strong>Overall, 14,597 patients were identified, of whom 6,220 were discharged to a rehabilitation facility, 2,647 to an intermediate care facility, and 5,730 to home. Significant factors associated with discharge to a rehabilitation facility compared to home included age, injury location and severity, insurance type, estimated length of stay, systolic blood pressure at admission, and admission blood alcohol level and drug screen results. Similarly, when comparing discharge to a rehabilitation facility with discharge to an intermediate care facility, sex, age, race, estimated length of stay, systolic blood pressure at admission, drug screen results, and coexisting substance use and metabolic conditions all significantly influenced disposition. Fine tree binary classification achieved a prediction accuracy of 72.5% when comparing discharge to a rehabilitation facility and home, and a prediction accuracy of 70.0% when comparing discharge to a rehabilitation facility and an intermediate care facility.</p><p><strong>Conclusions: </strong>This study demonstrates significant factors associated with discharge to a rehabilitation facility in patients with traumatic spinal cord injury. Further studies are needed to improve prediction accuracy.</p>","PeriodicalId":52698,"journal":{"name":"Journal of Trauma and Injury","volume":"38 3","pages":"255-267"},"PeriodicalIF":0.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12550874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silent ST elevation: unmasking blunt cardiac injury: a case report. 无症状ST段抬高:揭露钝性心脏损伤1例报告。
IF 0.2 Pub Date : 2025-09-01 Epub Date: 2025-06-25 DOI: 10.20408/jti.2025.0034
Vasudha Dinesh, Arun A Mohanan, Swetha Ramesh, Amaravathi Uthayakumar

Blunt cardiac injury is a rare but serious complication of thoracic trauma. We present the case of a 22-year-old male pedestrian involved in a road traffic accident (pedestrian vs. four‑wheeler) who was found to have ST‑segment elevation on electrocardiography during trauma evaluation. Despite being hemodynamically stable and lacking clinical signs or symptoms of cardiac injury, his electrocardiography showed ST elevations in the inferior leads. This case underscores the importance of vigilant cardiac monitoring in polytrauma patients, in whom blunt cardiac injury may be easily overlooked.

钝性心脏损伤是一种罕见但严重的胸外伤并发症。我们报告了一名22岁的男性行人卷入道路交通事故(行人与四轮车),他在创伤评估时发现心电图显示ST段抬高。尽管血流动力学稳定且无心脏损伤的临床体征或症状,但他的心电图显示下导联ST段升高。这个病例强调了在多发外伤患者中警惕心脏监测的重要性,在这些患者中,钝性心脏损伤很容易被忽视。
{"title":"Silent ST elevation: unmasking blunt cardiac injury: a case report.","authors":"Vasudha Dinesh, Arun A Mohanan, Swetha Ramesh, Amaravathi Uthayakumar","doi":"10.20408/jti.2025.0034","DOIUrl":"10.20408/jti.2025.0034","url":null,"abstract":"<p><p>Blunt cardiac injury is a rare but serious complication of thoracic trauma. We present the case of a 22-year-old male pedestrian involved in a road traffic accident (pedestrian vs. four‑wheeler) who was found to have ST‑segment elevation on electrocardiography during trauma evaluation. Despite being hemodynamically stable and lacking clinical signs or symptoms of cardiac injury, his electrocardiography showed ST elevations in the inferior leads. This case underscores the importance of vigilant cardiac monitoring in polytrauma patients, in whom blunt cardiac injury may be easily overlooked.</p>","PeriodicalId":52698,"journal":{"name":"Journal of Trauma and Injury","volume":" ","pages":"294-298"},"PeriodicalIF":0.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of base deficit and age shock index with in-hospital mortality in geriatric major trauma patients: a 1-year retrospective study at a single level I trauma center in Indonesia. 基础缺陷和年龄休克指数与老年重大创伤患者住院死亡率的相关性:印度尼西亚单一一级创伤中心的1年回顾性研究
IF 0.2 Pub Date : 2025-09-01 Epub Date: 2025-09-03 DOI: 10.20408/jti.2025.0021
Miftahul Khairat Musmar Elbama, M Iqbal Rivai, Irwan, Avit Suchitra, Aulia Rahman, Rose Dinda Martini

Purpose: Base deficit (BD) and age shock index have been utilized as an indicator of resuscitation adequacy and a predictor of poor outcomes in trauma cases, respectively. However, evidence regarding their correlation with in-hospital mortality among geriatric major trauma patients remains scarce in the literature.

Methods: This analytical observational study employed a retrospective cohort design involving 82 geriatric major trauma patients treated at our institution between November 2023 and November 2024. Data were collected from patients' medical records at admission (age, trauma mechanism, vital signs, Glasgow Coma Scale [GCS], Injury Severity Score, hemoglobin, BD, and comorbidities) and at discharge (survival or death).

Results: The geriatric major trauma patients who experienced in-hospital mortality were predominantly male, with an average age of 69.6 years. Traffic accidents constituted the most common trauma mechanism. Most patients presented with a GCS score between 13 and 15, and hypertension was the most frequently recorded comorbidity. BD demonstrated a significant correlation with in-hospital mortality (P<0.05). Severe BD was associated with the highest odds of in-hospital mortality (adjusted odds ratio, 40.72; 95% confidence interval, 2.90-560.86). Although age shock index did not directly correlate with mortality, it played a confounding role. Additionally, a GCS score of <9 was significantly correlated with in-hospital mortality (P<0.05).

Conclusions: The findings of this study can inform initial clinical management strategies for geriatric major trauma patients at trauma centers. Prompt resuscitation and treatment should be prioritized for patients presenting with moderate or severe BD to reduce preventable mortality in this population.

目的:基础缺陷(BD)和年龄休克指数分别被用作创伤病例复苏充分性的指标和不良预后的预测指标。然而,文献中关于它们与老年重大创伤患者住院死亡率相关性的证据仍然很少。方法:本分析性观察研究采用回顾性队列设计,纳入了2023年11月至2024年11月在我院治疗的82例老年严重创伤患者。数据收集自患者入院时的医疗记录(年龄、创伤机制、生命体征、格拉斯哥昏迷量表[GCS]、损伤严重程度评分、血红蛋白、BD和合并症)和出院时的医疗记录(生存或死亡)。结果:院内死亡的老年重大创伤患者以男性为主,平均年龄69.6岁。交通事故是最常见的创伤机制。大多数患者的GCS评分在13到15之间,高血压是最常见的合并症。结论:本研究结果可为创伤中心老年重大创伤患者的初步临床管理策略提供参考。对于出现中度或重度双相障碍的患者,应优先考虑及时复苏和治疗,以减少该人群中可预防的死亡率。
{"title":"Correlation of base deficit and age shock index with in-hospital mortality in geriatric major trauma patients: a 1-year retrospective study at a single level I trauma center in Indonesia.","authors":"Miftahul Khairat Musmar Elbama, M Iqbal Rivai, Irwan, Avit Suchitra, Aulia Rahman, Rose Dinda Martini","doi":"10.20408/jti.2025.0021","DOIUrl":"10.20408/jti.2025.0021","url":null,"abstract":"<p><strong>Purpose: </strong>Base deficit (BD) and age shock index have been utilized as an indicator of resuscitation adequacy and a predictor of poor outcomes in trauma cases, respectively. However, evidence regarding their correlation with in-hospital mortality among geriatric major trauma patients remains scarce in the literature.</p><p><strong>Methods: </strong>This analytical observational study employed a retrospective cohort design involving 82 geriatric major trauma patients treated at our institution between November 2023 and November 2024. Data were collected from patients' medical records at admission (age, trauma mechanism, vital signs, Glasgow Coma Scale [GCS], Injury Severity Score, hemoglobin, BD, and comorbidities) and at discharge (survival or death).</p><p><strong>Results: </strong>The geriatric major trauma patients who experienced in-hospital mortality were predominantly male, with an average age of 69.6 years. Traffic accidents constituted the most common trauma mechanism. Most patients presented with a GCS score between 13 and 15, and hypertension was the most frequently recorded comorbidity. BD demonstrated a significant correlation with in-hospital mortality (P<0.05). Severe BD was associated with the highest odds of in-hospital mortality (adjusted odds ratio, 40.72; 95% confidence interval, 2.90-560.86). Although age shock index did not directly correlate with mortality, it played a confounding role. Additionally, a GCS score of <9 was significantly correlated with in-hospital mortality (P<0.05).</p><p><strong>Conclusions: </strong>The findings of this study can inform initial clinical management strategies for geriatric major trauma patients at trauma centers. Prompt resuscitation and treatment should be prioritized for patients presenting with moderate or severe BD to reduce preventable mortality in this population.</p>","PeriodicalId":52698,"journal":{"name":"Journal of Trauma and Injury","volume":" ","pages":"204-210"},"PeriodicalIF":0.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence and predictors of mortality among traumatic brain injury patients in Ethiopia: a systematic review and meta-analysis. 埃塞俄比亚外伤性脑损伤患者的发病率和死亡率预测因素:系统回顾和荟萃分析。
IF 0.2 Pub Date : 2025-09-01 Epub Date: 2025-09-29 DOI: 10.20408/jti.2024.0104
Addisu Waleligne Tadesse, Derara Girma Tufa, Hiwot Dejene Dissassa, Melese Wagaye

Purpose: Traumatic brain injury (TBI) represents a significant public health concern due to its high incidence, substantial prevalence of chronic neuropsychiatric sequelae, disabilities, and economic burdens. Although several primary studies have examined mortality rates among individuals with TBI in Ethiopia, no systematic reviews and meta-analyses have yet synthesized these findings to provide a comprehensive nationwide estimate.

Methods: A systematic search for Ethiopian TBI mortality studies was conducted using PubMed, MEDLINE, Hinari, ScienceDirect, Ovid, the Web of Science, the Directory of Open Access Journals, and the African Journals Online. Following the PRISMA guidelines, we screened eligible studies, assessed quality with the Joanna Briggs Institute tool, and analyzed data in Stata ver. 18. A random-effects model estimated TBI mortality and the pooled odds ratios (PORs) of predictors. Heterogeneity (I2) was assessed, and subgroup analyses, meta-regression, forest plots, and funnel plots with Egger and Begg tests addressed variability and publication bias.

Results: Of 100 records, 23 studies (n=7,866) met inclusion. The pooled incidence of mortality from TBI in Ethiopia was 15.69% (95% confidence interval [CI], 12.41-18.96). Regional incidence varied from 3.15% (95% CI, 1.23-5.08) in the Sidama Region to 39.42% (95% CI, 33.25-45.59) in the Amhara Region. Identified predictors of mortality included aspiration pneumonia (POR, 10.41; 95% CI, 3.25-33.40), penetrating injury (POR, 1.76; 95% CI, 1.07-2.90), road traffic accident injuries (POR, 1.71; 95% CI, 1.11-2.64), severe Glasgow Coma Scale (GCS) scores (POR, 18.94; 95% CI, 7.37-48.7), moderate GCS scores (POR, 2.95; 95% CI, 1.60-5.44), bilateral pupillary reaction (POR, 24.56; 95% CI, 7.72-78.19), unilateral pupillary reaction (POR, 7.75; 95% CI, 4.45-13.48), hypoxia (POR, 8.22; 95% CI, 2.42-27.98), concomitant injuries (POR, 2.15; 95% CI, 1.05-4.38), complications (POR, 4.76; 95% CI, 2.49-9.09), surgical management (POR, 0.58; 95% CI, 0.36-0.94), and mechanical ventilation (POR, 4.45; 95% CI, 2.00-9.88).

Conclusions: The high TBI mortality in Ethiopia underscores the urgent need to expand advanced trauma care centers, deploy trained personnel beyond urban areas, and strengthen road safety policies to achieve Sustainable Development Goal targets by 2030.

目的:外伤性脑损伤(TBI)由于其高发病率、慢性神经精神后遗症、残疾和经济负担的普遍存在,是一个重要的公共卫生问题。尽管有几项初步研究调查了埃塞俄比亚TBI患者的死亡率,但尚未有系统的综述和荟萃分析将这些发现综合起来,以提供全面的全国估计。方法:使用PubMed、MEDLINE、Hinari、ScienceDirect、Ovid、Web of Science、Open Access Journals Directory和the African Journals Online对埃塞俄比亚TBI死亡率研究进行系统搜索。遵循PRISMA指南,我们筛选了符合条件的研究,使用Joanna Briggs Institute工具评估质量,并在Stata ver中分析数据。18. 随机效应模型估计TBI死亡率和预测因子的合并优势比(por)。异质性(I2)被评估,亚组分析、meta回归、森林图和漏斗图采用Egger和Begg检验来解决变异性和发表偏倚。结果:在100条记录中,23项研究(n= 7866)符合纳入标准。埃塞俄比亚TBI的总死亡率为15.69%(95%可信区间[CI], 12.41-18.96)。地区发病率从西达马地区的3.15% (95% CI, 1.23-5.08)到阿姆哈拉地区的39.42% (95% CI, 33.25-45.59)不等。确定的死亡预测因素包括吸入性肺炎(POR, 10.41, 95% CI, 3.25-33.40)、穿透性损伤(POR, 1.76, 95% CI, 1.07-2.90)、道路交通事故伤害(POR, 1.71, 95% CI, 1.11-2.64)、严重格拉斯哥昏迷评分(GCS) (POR, 18.94, 95% CI, 7.37-48.7)、中度格拉斯哥昏迷评分(POR, 2.95, 95% CI, 1.60-5.44)、双侧瞳孔反应(POR, 24.56, 95% CI, 7.72-78.19)、单侧瞳孔反应(POR, 7.75, 95% CI, 4.45-13.48)、缺氧(POR, 8.22;95% CI, 2.42-27.98)、伴随损伤(POR, 2.15; 95% CI, 1.05-4.38)、并发症(POR, 4.76; 95% CI, 2.49-9.09)、手术处理(POR, 0.58; 95% CI, 0.36-0.94)和机械通气(POR, 4.45; 95% CI, 2.00-9.88)。结论:埃塞俄比亚的高创伤性脑损伤死亡率表明,迫切需要扩大先进的创伤护理中心,在城市地区以外部署训练有素的人员,并加强道路安全政策,以实现到2030年的可持续发展目标。
{"title":"Incidence and predictors of mortality among traumatic brain injury patients in Ethiopia: a systematic review and meta-analysis.","authors":"Addisu Waleligne Tadesse, Derara Girma Tufa, Hiwot Dejene Dissassa, Melese Wagaye","doi":"10.20408/jti.2024.0104","DOIUrl":"10.20408/jti.2024.0104","url":null,"abstract":"<p><strong>Purpose: </strong>Traumatic brain injury (TBI) represents a significant public health concern due to its high incidence, substantial prevalence of chronic neuropsychiatric sequelae, disabilities, and economic burdens. Although several primary studies have examined mortality rates among individuals with TBI in Ethiopia, no systematic reviews and meta-analyses have yet synthesized these findings to provide a comprehensive nationwide estimate.</p><p><strong>Methods: </strong>A systematic search for Ethiopian TBI mortality studies was conducted using PubMed, MEDLINE, Hinari, ScienceDirect, Ovid, the Web of Science, the Directory of Open Access Journals, and the African Journals Online. Following the PRISMA guidelines, we screened eligible studies, assessed quality with the Joanna Briggs Institute tool, and analyzed data in Stata ver. 18. A random-effects model estimated TBI mortality and the pooled odds ratios (PORs) of predictors. Heterogeneity (I2) was assessed, and subgroup analyses, meta-regression, forest plots, and funnel plots with Egger and Begg tests addressed variability and publication bias.</p><p><strong>Results: </strong>Of 100 records, 23 studies (n=7,866) met inclusion. The pooled incidence of mortality from TBI in Ethiopia was 15.69% (95% confidence interval [CI], 12.41-18.96). Regional incidence varied from 3.15% (95% CI, 1.23-5.08) in the Sidama Region to 39.42% (95% CI, 33.25-45.59) in the Amhara Region. Identified predictors of mortality included aspiration pneumonia (POR, 10.41; 95% CI, 3.25-33.40), penetrating injury (POR, 1.76; 95% CI, 1.07-2.90), road traffic accident injuries (POR, 1.71; 95% CI, 1.11-2.64), severe Glasgow Coma Scale (GCS) scores (POR, 18.94; 95% CI, 7.37-48.7), moderate GCS scores (POR, 2.95; 95% CI, 1.60-5.44), bilateral pupillary reaction (POR, 24.56; 95% CI, 7.72-78.19), unilateral pupillary reaction (POR, 7.75; 95% CI, 4.45-13.48), hypoxia (POR, 8.22; 95% CI, 2.42-27.98), concomitant injuries (POR, 2.15; 95% CI, 1.05-4.38), complications (POR, 4.76; 95% CI, 2.49-9.09), surgical management (POR, 0.58; 95% CI, 0.36-0.94), and mechanical ventilation (POR, 4.45; 95% CI, 2.00-9.88).</p><p><strong>Conclusions: </strong>The high TBI mortality in Ethiopia underscores the urgent need to expand advanced trauma care centers, deploy trained personnel beyond urban areas, and strengthen road safety policies to achieve Sustainable Development Goal targets by 2030.</p>","PeriodicalId":52698,"journal":{"name":"Journal of Trauma and Injury","volume":"38 3","pages":"181-194"},"PeriodicalIF":0.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Trauma and Injury
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