Pub Date : 2018-06-30DOI: 10.18004/RDN2018.0010.01.017-035
Patricia Abigail Arias Yrazusta, Gladys Maribel Godoy Torales, G. Samudio, C. Aparicio
Introduction: in recent decades, the agent of choice for the treatment of Artículo original Efectos adversos de anfotericina B desoxicolato en neonatos del Hospital Nacional de Itauguá Adverse effects of amphotericin B deoxycholate in neonates of the National Hospital of Itauguá Patricia Abigail Arias Yrazusta, Gladys Godoy Torales, Gloria Samudio, Chantal Marie Real Aparicio DEL NACIONAL Rev. Nac (Itauguá) 2018;10(1):017-035 10.18004/rdn2018.0010.01.017-035 most systemic mycoses has been amphotericin B which, despite the toxic effects, continues to play an important role in the treatment of fungal infections. Objective: to determine the adverse effects associated with the use of amphotericin B in neonates of the Neonatology Service of the National Hospital of Itauguá, in the period 2013 2015. Materials and methods: retrospective case series study of newborns treated with amphotericin B. Results: among 28 newborns treated with amphotericin B, there was a higher prevalence in males. With regard to age, more than half of the newborns were pre-term in the group studied. There was a predominance of low birth weight (32.14%). The risk factors showed that 53.5% did not have a history of sepsis. The mean age of onset of amphotericin was 19 ± 9 days, more than half of the infants used progressive dose from 0.5 mg / kp / day to 1 mg / kp / day, in 24 hours. 96.4% received infusion of amphotericin B for 4 hours, 1 case required 6 hours. Among the side effects, 35.7% of the patients presented anemia, the most frequent water and electrolyte disturbance was hypokalemia, among the signs were tachycardia and hypotension. Conclusions: the most striking side effects found during treatment with amphotericin B were anemia, Sodium and Potassium alterations.
简介：近几十年来，Artículo治疗意大利国家医院新生婴儿的首选药物阿替卡林B脱氧胆酸盐对意大利国家医院新生儿的不良影响Patricia Abigail Arias Yrazusta、Gladys Godoy Torales、Gloria Samudio、Chantal Marie Real Aparicio del Nacional Rev。Nac（意大利）2018；10（1）：017-035 10.18004/rdn2018.0010.01.017-035大多数系统性真菌病都是两性霉素B，尽管有毒性作用，但它在真菌感染的治疗中仍然发挥着重要作用。目的：确定2013年至2015年期间，意大利国立医院新生儿服务中心在新生儿中使用两性霉素B的不良反应。材料和方法：对接受两性霉素B治疗的新生儿进行回顾性病例系列研究。结果：在接受两性蛋白酶B治疗的28名新生儿中，男性的患病率较高。就年龄而言，研究组中超过一半的新生儿是足月前出生的。以低出生体重为主（32.14%），危险因素显示53.5%无败血症史。两性霉素的平均发病年龄为19±9天，超过一半的婴儿在24小时内使用了从0.5mg/kp/天到1mg/kp/天的渐进剂量。96.4%的患者输注两性霉素B 4小时，1例需输注6小时。在副作用中，35.7%的患者表现为贫血，最常见的水和电解质紊乱是低钾血症，其中体征是心动过速和低血压。结论：两性霉素B治疗期间发现的最显著的副作用是贫血、钠和钾的改变。
{"title":"Adverse effects of amphotericin B deoxycholate in neonates of the National Hospital of Itauguá","authors":"Patricia Abigail Arias Yrazusta, Gladys Maribel Godoy Torales, G. Samudio, C. Aparicio","doi":"10.18004/RDN2018.0010.01.017-035","DOIUrl":"https://doi.org/10.18004/RDN2018.0010.01.017-035","url":null,"abstract":"Introduction: in recent decades, the agent of choice for the treatment of Artículo original Efectos adversos de anfotericina B desoxicolato en neonatos del Hospital Nacional de Itauguá Adverse effects of amphotericin B deoxycholate in neonates of the National Hospital of Itauguá Patricia Abigail Arias Yrazusta, Gladys Godoy Torales, Gloria Samudio, Chantal Marie Real Aparicio DEL NACIONAL Rev. Nac (Itauguá) 2018;10(1):017-035 10.18004/rdn2018.0010.01.017-035 most systemic mycoses has been amphotericin B which, despite the toxic effects, continues to play an important role in the treatment of fungal infections. Objective: to determine the adverse effects associated with the use of amphotericin B in neonates of the Neonatology Service of the National Hospital of Itauguá, in the period 2013 2015. Materials and methods: retrospective case series study of newborns treated with amphotericin B. Results: among 28 newborns treated with amphotericin B, there was a higher prevalence in males. With regard to age, more than half of the newborns were pre-term in the group studied. There was a predominance of low birth weight (32.14%). The risk factors showed that 53.5% did not have a history of sepsis. The mean age of onset of amphotericin was 19 ± 9 days, more than half of the infants used progressive dose from 0.5 mg / kp / day to 1 mg / kp / day, in 24 hours. 96.4% received infusion of amphotericin B for 4 hours, 1 case required 6 hours. Among the side effects, 35.7% of the patients presented anemia, the most frequent water and electrolyte disturbance was hypokalemia, among the signs were tachycardia and hypotension. Conclusions: the most striking side effects found during treatment with amphotericin B were anemia, Sodium and Potassium alterations.","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46090471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.18004/rdn2018.0010.01.057-067
Roger Mareco Martínez
Introduction: Preterm birth is the cause of the greatest number of neonatal deaths worldwide and also of neurological sequels, this implies a high cost for the family and the State. Many studies have already been done to try to prevent it. Objective: to update the ultrasound methods used to diagnose cervical alterations in relation to preterm delivery. Results: transvaginal ultrasound can measure and evaluate the characteristics of the cervix in pregnant women, which is why it is the most widely used method to identify women at risk of spontaneous preterm birth, and it can be used as screening due to its accessible cost and availability in the Health services. Conclusions: the ultrasound measurement of the length of the cervix at 23 weeks of gestation represents the best independent predictor for delivery before 32 weeks. Artículo original Medición ecográfica de la longitud cervical y riesgo de parto
{"title":"Ultrasound measurement of cervical length and risk of preterm birth","authors":"Roger Mareco Martínez","doi":"10.18004/rdn2018.0010.01.057-067","DOIUrl":"https://doi.org/10.18004/rdn2018.0010.01.057-067","url":null,"abstract":"Introduction: Preterm birth is the cause of the greatest number of neonatal deaths worldwide and also of neurological sequels, this implies a high cost for the family and the State. Many studies have already been done to try to prevent it. Objective: to update the ultrasound methods used to diagnose cervical alterations in relation to preterm delivery. Results: transvaginal ultrasound can measure and evaluate the characteristics of the cervix in pregnant women, which is why it is the most widely used method to identify women at risk of spontaneous preterm birth, and it can be used as screening due to its accessible cost and availability in the Health services. Conclusions: the ultrasound measurement of the length of the cervix at 23 weeks of gestation represents the best independent predictor for delivery before 32 weeks. Artículo original Medición ecográfica de la longitud cervical y riesgo de parto","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67547997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.18004/RDN2018.0010.01.131-134
Hugo Gustavo Kunzle-Elizeche, C. A. Domínguez, S. Enriquez, Á. González, J. C. Melgarejo
{"title":"Post-traumatic axillary artery injury associated with scapula fracture","authors":"Hugo Gustavo Kunzle-Elizeche, C. A. Domínguez, S. Enriquez, Á. González, J. C. Melgarejo","doi":"10.18004/RDN2018.0010.01.131-134","DOIUrl":"https://doi.org/10.18004/RDN2018.0010.01.131-134","url":null,"abstract":"","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44833169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.18004/rdn2018.0010.01.147-149
Hugo Gustavo Kunzle-Elizeche, D. González-Fernández
{"title":"Requirements to publish letters to the editor in biomedical journals SciELO Paraguay","authors":"Hugo Gustavo Kunzle-Elizeche, D. González-Fernández","doi":"10.18004/rdn2018.0010.01.147-149","DOIUrl":"https://doi.org/10.18004/rdn2018.0010.01.147-149","url":null,"abstract":"","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47100899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.18004/RDN2018.0010.01.144-146
C. Rios-González
{"title":"Zika infection in Paraguay: an epidemiological approach","authors":"C. Rios-González","doi":"10.18004/RDN2018.0010.01.144-146","DOIUrl":"https://doi.org/10.18004/RDN2018.0010.01.144-146","url":null,"abstract":"","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48060649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.18004/rdn2018.0010.01.068-091
María Constanza Real Aparicio
{"title":"Temporomandibular dysfunction: causes and treatments","authors":"María Constanza Real Aparicio","doi":"10.18004/rdn2018.0010.01.068-091","DOIUrl":"https://doi.org/10.18004/rdn2018.0010.01.068-091","url":null,"abstract":"","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67548008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.18004/RDN2018.0010.01.036-056
C. Aparicio, Lorena Spinzi, F. Romero
Introduction: ventricular septal defect (VSD) is a frequent congenital heart disease, which varies from a minute defect without hemodynamic consequences to a large defect, accompanied by heart failure and pulmonary hypertension. Although medical treatment manages to control heart failure, it is undoubted that in some cases surgical closure is necessary. Objective: to describe the clinical characteristics of the pre- and post-operative of patients undergoing IVC closure. Methodology: observational, descriptive, retrospective study, which included 74 patients from 3 months to 16 years of age, undergoing surgical closure of VSD in the Pediatric Cardiology Department of Hospital de Clínicas FCM-UNA in the 2012-2017 period. Clinical, electrocardiographic and echocardiographic variables are described in the pre- and postoperative period. Cases of intra-operative death, cases with complex congenital heart defects associated with VSD and atrioventricular canal were excluded. Results: the most frequently intervened VSD was the perimembranous type (95%) and the majority with preoperative grade I functional class (52%). Post-operative parameters (electrocardiogram and echocardiography) normalized in most patients, with a decrease in evidence of cardiac chamber overload. Infectious (67%) and pulmonary (pneumothorax and atelectasis) complications occurred. The mortality was 1.3%. Conclusion: Surgical closure of the VSD had significant morbidity, low mortality and excellent functional recovery.
{"title":"Characteristics of post-operated patients of interventricular communication in the Department of Pediatric Cardiology of the Hospital de Clinics","authors":"C. Aparicio, Lorena Spinzi, F. Romero","doi":"10.18004/RDN2018.0010.01.036-056","DOIUrl":"https://doi.org/10.18004/RDN2018.0010.01.036-056","url":null,"abstract":"Introduction: ventricular septal defect (VSD) is a frequent congenital heart disease, which varies from a minute defect without hemodynamic consequences to a large defect, accompanied by heart failure and pulmonary hypertension. Although medical treatment manages to control heart failure, it is undoubted that in some cases surgical closure is necessary. Objective: to describe the clinical characteristics of the pre- and post-operative of patients undergoing IVC closure. Methodology: observational, descriptive, retrospective study, which included 74 patients from 3 months to 16 years of age, undergoing surgical closure of VSD in the Pediatric Cardiology Department of Hospital de Clínicas FCM-UNA in the 2012-2017 period. Clinical, electrocardiographic and echocardiographic variables are described in the pre- and postoperative period. Cases of intra-operative death, cases with complex congenital heart defects associated with VSD and atrioventricular canal were excluded. Results: the most frequently intervened VSD was the perimembranous type (95%) and the majority with preoperative grade I functional class (52%). Post-operative parameters (electrocardiogram and echocardiography) normalized in most patients, with a decrease in evidence of cardiac chamber overload. Infectious (67%) and pulmonary (pneumothorax and atelectasis) complications occurred. The mortality was 1.3%. Conclusion: Surgical closure of the VSD had significant morbidity, low mortality and excellent functional recovery.","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48625409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.18004/rdn2018.0010.01.001-003
Lis Kharinne Pérez Ibarra
{"title":"Occupational exposure to blood and body fluids","authors":"Lis Kharinne Pérez Ibarra","doi":"10.18004/rdn2018.0010.01.001-003","DOIUrl":"https://doi.org/10.18004/rdn2018.0010.01.001-003","url":null,"abstract":"","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42737588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.18004/RDN2018.0010.01.124-130
Lorenzo Diosnel Acosta Brunaga, S. Cabañas, Diego Julián Fleitas Oviedo, C. Chamorro, P. Portillo
We present a clinical case of intestinal perforation for chicken bone treated at the Central Hospital of the Social Security Institute (IPS). The patient was a 71-year-old woman who was referred from another center with 24 hs abdominal pain, with nausea and vomiting. Laparoscopic surgery, a was done and sigmoid perforation was found by foreign body (chicken bone) that was treated with primary suture of the perforation and laparoscopic drainage of the cavity.
{"title":"Colonic perforation by foreign body","authors":"Lorenzo Diosnel Acosta Brunaga, S. Cabañas, Diego Julián Fleitas Oviedo, C. Chamorro, P. Portillo","doi":"10.18004/RDN2018.0010.01.124-130","DOIUrl":"https://doi.org/10.18004/RDN2018.0010.01.124-130","url":null,"abstract":"We present a clinical case of intestinal perforation for chicken bone treated at the Central Hospital of the Social Security Institute (IPS). The patient was a 71-year-old woman who was referred from another center with 24 hs abdominal pain, with nausea and vomiting. Laparoscopic surgery, a was done and sigmoid perforation was found by foreign body (chicken bone) that was treated with primary suture of the perforation and laparoscopic drainage of the cavity.","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46461270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.18004/rdn2018.0010.01.135-143
Lorenzo Diosnel Acosta Brunaga, Diego Julián Fleitas Oviedo, F. González
Intestinal injuries due to blunt or closed abdominal trauma are less frequent; however, they represent the third most injured frecuent organ for this cause. Early diagnosis of intestinal injure is difficult and any delay is associated with high morbidity and mortality. The complementary study for its diagnosis in a stable patient is tomography. We present a case of a 56 years old woman who attended goes to the Emergency Service for a history of motor vehicle accident. Based on predictive criteria for intestinal and mesenteric lesions, emergency surgery was indicated, getting an early diagnosis and treatment of intestinal lesion in blunt trauma by laparoscopy. Caso Clínico Manejo de lesión intestinal por laparoscopia Management of intestinal injury by laparoscopy Lorenzo Diosnel Acosta Brunaga, Diego Julián Fleitas Oviedo, Fernando González DEL NACIONAL Rev. Nac (Itauguá) 2018;10(1):135-143 10.18004/rdn2018.0010.01.135-143
钝性或闭合性腹部创伤造成的肠道损伤不太常见；然而，它们是第三大受伤的器官。肠损伤的早期诊断很困难，任何延误都会导致高发病率和死亡率。对稳定患者进行诊断的补充研究是断层扫描。我们介绍了一个案例，一位56岁的女性因有机动车事故史而前往急救中心。根据肠道和肠系膜病变的预测标准，建议急诊手术，通过腹腔镜对钝性创伤中的肠道病变进行早期诊断和治疗。Caso Clínico Manejo de lesión肠道腹腔镜治疗肠道损伤Lorenzo Diosnel Acosta Brunaga，Diego Julián Fleitas Oviedo，Fernando González DEL NACIONAL Rev.Nac（意大利）2018；10（1）：135-143 10.18004/rdn2018.0010.01.135-143
{"title":"Management of intestinal injury by laparoscopy","authors":"Lorenzo Diosnel Acosta Brunaga, Diego Julián Fleitas Oviedo, F. González","doi":"10.18004/rdn2018.0010.01.135-143","DOIUrl":"https://doi.org/10.18004/rdn2018.0010.01.135-143","url":null,"abstract":"Intestinal injuries due to blunt or closed abdominal trauma are less frequent; however, they represent the third most injured frecuent organ for this cause. Early diagnosis of intestinal injure is difficult and any delay is associated with high morbidity and mortality. The complementary study for its diagnosis in a stable patient is tomography. We present a case of a 56 years old woman who attended goes to the Emergency Service for a history of motor vehicle accident. Based on predictive criteria for intestinal and mesenteric lesions, emergency surgery was indicated, getting an early diagnosis and treatment of intestinal lesion in blunt trauma by laparoscopy. Caso Clínico Manejo de lesión intestinal por laparoscopia Management of intestinal injury by laparoscopy Lorenzo Diosnel Acosta Brunaga, Diego Julián Fleitas Oviedo, Fernando González DEL NACIONAL Rev. Nac (Itauguá) 2018;10(1):135-143 10.18004/rdn2018.0010.01.135-143","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48035203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：