Bladder diverticulum rarely causes deep vein thrombosis (DVT) due to compression of leg veins. However, only a few cases have been reported to date. In this article, we report the first known case of DVT caused by a giant bladder diverticulum associated with long-term use of antipsychotic medication.
Case Presentation
A male in his 40s with a 20-year history of schizophrenia was admitted to the hospital with complaints of swelling and pain in the left lower extremity. He was diagnosed with drug-induced urinary retention caused by antipsychotics, a giant bladder diverticulum, and DVT. The patient underwent urinary catheter placement and was treated with rivaroxaban. He has limited therapeutic options due to poor adherence to treatment and is currently undergoing intermittent replacement of the urinary catheter.
Conclusion
Patients taking antipsychotic medications must be aware of the risk of urinary retention and may be unable to choose optimal medical care.
{"title":"Deep Vein Thrombosis Caused by Drug-Induced Giant Bladder Diverticulum in Long-Term Use of Antipsychotic Drugs: Case Report and Literature Review","authors":"Kazuki Sato, Kotaro Hirai, Yumiko Yokomizo, Azumi Fujioka, Yuki Ito, Yuichi Sugiyama, Yuko Hishiki","doi":"10.1002/iju5.70094","DOIUrl":"https://doi.org/10.1002/iju5.70094","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Bladder diverticulum rarely causes deep vein thrombosis (DVT) due to compression of leg veins. However, only a few cases have been reported to date. In this article, we report the first known case of DVT caused by a giant bladder diverticulum associated with long-term use of antipsychotic medication.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A male in his 40s with a 20-year history of schizophrenia was admitted to the hospital with complaints of swelling and pain in the left lower extremity. He was diagnosed with drug-induced urinary retention caused by antipsychotics, a giant bladder diverticulum, and DVT. The patient underwent urinary catheter placement and was treated with rivaroxaban. He has limited therapeutic options due to poor adherence to treatment and is currently undergoing intermittent replacement of the urinary catheter.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Patients taking antipsychotic medications must be aware of the risk of urinary retention and may be unable to choose optimal medical care.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 6","pages":"583-586"},"PeriodicalIF":0.0,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We present a case of carcinoma in situ (CIS) of the bilateral upper urinary tract (UUT) in which long-term complete remission was achieved through retrograde perfusion of Bacillus Calmette–Guérin (BCG) via open-ended ureteral catheters following the failure of endoluminal therapy using double-J stents.
Case Presentation
A 52-year-old male patient was diagnosed with CIS of the bilateral UUT and bladder. Intravesical BCG instillation using double-J stents failed to eradicate persistently positive catheter urine cytology from the bilateral UUT. Since the patient strongly desired kidney-sparing treatment, retrograde BCG perfusion via open-ended ureteral catheter was performed. This treatment resulted in durable complete remission lasting 3 years.
Conclusions
Retrograde BCG treatment via double-J stent may result in suboptimal efficacy due to limited drug exposure to the UUT urothelium. In cases in which kidney-sparing treatment is required, retrograde BCG perfusion via open-ended ureteral catheters may be considered a viable therapeutic option.
{"title":"A Case of Complete Remission of Bilateral Upper Tract Carcinoma In Situ Following Retrograde Bacillus Calmette–Guérin (\u0000 BCG\u0000 ) Instillation via Open-Ended Ureteral Catheters After Failure Using Double-J Stents","authors":"Nanaka Katsurayama, Toshihide Horiuchi, Koichi Nishimura, Kazutaka Nakamura, Takanori Endo, Yuki Nemoto, Nao Nakajima, Daisuke Toki, Tsunenori Kondo","doi":"10.1002/iju5.70092","DOIUrl":"https://doi.org/10.1002/iju5.70092","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>We present a case of carcinoma in situ (CIS) of the bilateral upper urinary tract (UUT) in which long-term complete remission was achieved through retrograde perfusion of Bacillus Calmette–Guérin (BCG) via open-ended ureteral catheters following the failure of endoluminal therapy using double-J stents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 52-year-old male patient was diagnosed with CIS of the bilateral UUT and bladder. Intravesical BCG instillation using double-J stents failed to eradicate persistently positive catheter urine cytology from the bilateral UUT. Since the patient strongly desired kidney-sparing treatment, retrograde BCG perfusion via open-ended ureteral catheter was performed. This treatment resulted in durable complete remission lasting 3 years.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Retrograde BCG treatment via double-J stent may result in suboptimal efficacy due to limited drug exposure to the UUT urothelium. In cases in which kidney-sparing treatment is required, retrograde BCG perfusion via open-ended ureteral catheters may be considered a viable therapeutic option.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 6","pages":"575-577"},"PeriodicalIF":0.0,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70092","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Synchronous bilateral renal cell carcinoma is a rare clinical entity that poses considerable challenges in establishing an optimal treatment strategy.
Case Presentation
A 56-year-old woman had synchronous bilateral renal cell carcinoma, with tumors in the right (61 mm) and left (71 mm) kidneys. Systemic therapy with pembrolizumab and lenvatinib was administered for five months, resulting in tumor reduction to 35 mm (right) and 52 mm (left). This facilitated right partial nephrectomy and then left radical nephrectomy to achieve complete tumor resection with preserved renal function and avoidance of dialysis.
Conclusion
Pre-surgical therapy with pembrolizumab and lenvatinib effectively shrank the initially unresectable renal tumors to enable successful partial nephrectomy. This approach may be viable for patients with large bilateral renal masses.
{"title":"Synchronous Bilateral Large Renal Cell Carcinoma Treated With Presurgical Pembrolizumab and Lenvatinib Enabling Unilateral Partial Nephrectomy and Dialysis Avoidance: A Case Report","authors":"Hiroki Kawabata, Shimpei Yamashita, Yuya Iwahashi, Satoshi Muraoka, Takahito Wakamiya, Yasuo Kohjimoto, Isao Hara","doi":"10.1002/iju5.70095","DOIUrl":"https://doi.org/10.1002/iju5.70095","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Synchronous bilateral renal cell carcinoma is a rare clinical entity that poses considerable challenges in establishing an optimal treatment strategy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 56-year-old woman had synchronous bilateral renal cell carcinoma, with tumors in the right (61 mm) and left (71 mm) kidneys. Systemic therapy with pembrolizumab and lenvatinib was administered for five months, resulting in tumor reduction to 35 mm (right) and 52 mm (left). This facilitated right partial nephrectomy and then left radical nephrectomy to achieve complete tumor resection with preserved renal function and avoidance of dialysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Pre-surgical therapy with pembrolizumab and lenvatinib effectively shrank the initially unresectable renal tumors to enable successful partial nephrectomy. This approach may be viable for patients with large bilateral renal masses.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 6","pages":"587-590"},"PeriodicalIF":0.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70095","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ureterosciatic hernia is a rare condition in which the ureter herniates through the sciatic foramen, causing ureteral obstruction, and urinary infection.
Case Presentation
A 72-year-old woman presented with left flank pain. Computed tomography revealed left hydronephrosis with ureterosciatic hernia. During treatment planning, she developed a cerebral infarction and worsening angina, and received conservative management. One year later, computed tomography showed spontaneous resolution of the hernia. Subsequently, she experienced left flank pain, and repeat computed tomography demonstrated recurrence of the hernia with emphysematous pyelonephritis. Due to the high surgical risk, she underwent antibiotic therapy and stepwise retrograde ureteral realignment with ureteral catheter insertion, followed by double-J stent replacement.
Conclusion
This is the first report to describe the spontaneous resolution and intermittent recurrence of ureterosciatic hernia on serial radiographic examinations. Retrograde ureteral realignment may be a safe and effective alternative to surgical repair in frail patients.
{"title":"Intermittent Recurrence of Ureterosciatic Hernia After Spontaneous Resolution, Complicated by Emphysematous Pyelonephritis","authors":"Akira Ohtsu, Keisuke Hori, Seiji Arai, Yuki Morimura, Ayaka Igarashi, Yuji Fujizuka, Yoshitaka Sekine, Hidekazu Koike, Hiroshi Matsui, Kazuhiro Suzuki","doi":"10.1002/iju5.70096","DOIUrl":"https://doi.org/10.1002/iju5.70096","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Ureterosciatic hernia is a rare condition in which the ureter herniates through the sciatic foramen, causing ureteral obstruction, and urinary infection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 72-year-old woman presented with left flank pain. Computed tomography revealed left hydronephrosis with ureterosciatic hernia. During treatment planning, she developed a cerebral infarction and worsening angina, and received conservative management. One year later, computed tomography showed spontaneous resolution of the hernia. Subsequently, she experienced left flank pain, and repeat computed tomography demonstrated recurrence of the hernia with emphysematous pyelonephritis. Due to the high surgical risk, she underwent antibiotic therapy and stepwise retrograde ureteral realignment with ureteral catheter insertion, followed by double-J stent replacement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This is the first report to describe the spontaneous resolution and intermittent recurrence of ureterosciatic hernia on serial radiographic examinations. Retrograde ureteral realignment may be a safe and effective alternative to surgical repair in frail patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 6","pages":"591-595"},"PeriodicalIF":0.0,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70096","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Testicular germ cell tumors (GCTs) are rare cancers. Mature teratomas may rarely undergo somatic malignant transformation (SMT) and may exhibit histological features resembling those of sarcomas.
Case
A 22-year-old male presented to our hospital with a complaint of a left scrotal mass. Under a diagnosis of metastatic mixed germ cell tumor, high inguinal orchiectomy was performed, followed by chemotherapy, retroperitoneal lymph node dissection, and metastasectomy. A liver specimen showed residual mature teratoma. Three years later, a left renal mass was found, and resection was performed. Histopathological examination confirmed it to be liposarcoma derived from mature teratoma.
{"title":"Liposarcoma Arising From Mature Teratoma Following Testicular Tumor Surgery: A Case Report","authors":"Mai Yamazaki, Kousuke Kitamura, Kanako Ogura, Gento Oomae, Kazuhiko Mizushima, Takahiro Nonami, Yuto Miyoshi, Yoshirou Sakamoto, Satoru Muto","doi":"10.1002/iju5.70091","DOIUrl":"https://doi.org/10.1002/iju5.70091","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Testicular germ cell tumors (GCTs) are rare cancers. Mature teratomas may rarely undergo somatic malignant transformation (SMT) and may exhibit histological features resembling those of sarcomas.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case</h3>\u0000 \u0000 <p>A 22-year-old male presented to our hospital with a complaint of a left scrotal mass. Under a diagnosis of metastatic mixed germ cell tumor, high inguinal orchiectomy was performed, followed by chemotherapy, retroperitoneal lymph node dissection, and metastasectomy. A liver specimen showed residual mature teratoma. Three years later, a left renal mass was found, and resection was performed. Histopathological examination confirmed it to be liposarcoma derived from mature teratoma.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 6","pages":"571-574"},"PeriodicalIF":0.0,"publicationDate":"2025-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70091","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Hiraguri, Y. Sato, J. Hata, et al., “Bilateral High Intra-Abdominal Testes Successfully Treated With Multistage Fowler–Stephens Orchiopexy to Preserve Testicular Function,” IJU Case Reports 8, no. 4 (2025): 427–430.
The image originally published as Figure 4 contains an error; the correct version of Figure 4 is as follows.
We apologize for this error.
A. Hiraguri， Y. Sato， J. Hata，等，“多阶段Fowler-Stephens睾丸切除术成功治疗双侧高腹内睾丸以保持睾丸功能”，《IJU病例报告》第8期。4(2025): 427-430。最初作为图4发布的图像包含一个错误；图4的正确版本如下所示。我们为这个错误道歉。
{"title":"Correction to “Bilateral High Intra-Abdominal Testes Successfully Treated With Multistage Fowler–Stephens Orchiopexy to Preserve Testicular Function”","authors":"","doi":"10.1002/iju5.70087","DOIUrl":"https://doi.org/10.1002/iju5.70087","url":null,"abstract":"<p>A. Hiraguri, Y. Sato, J. Hata, et al., “Bilateral High Intra-Abdominal Testes Successfully Treated With Multistage Fowler–Stephens Orchiopexy to Preserve Testicular Function,” <i>IJU Case Reports</i> 8, no. 4 (2025): 427–430.</p><p>The image originally published as Figure 4 contains an error; the correct version of Figure 4 is as follows.</p><p>We apologize for this error.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70087","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Priapism is a persistent penile erection lasting > 4 h without sexual stimulation. Ischemic priapism requires urgent management. We report a recurrent ischemic priapism case post-living-donor kidney transplantation necessitating multiple interventions, including bilateral T-shunt procedures.
Case Presentation
A 44-year-old man with end-stage kidney disease from malignant nephrosclerosis and IgA nephropathy underwent living-donor kidney transplantation. On postoperative Day 5, priapism appeared upon catheter removal. Bedside corporal aspiration was initially performed. Recurrence prompted Winter's shunt on Day 6. Blood gas analysis confirmed ischemic priapism. On Day 7, further recurrence required bilateral T-shunts, resolving the condition. Propofol, used during anesthesia, was suspected as the cause. At the 6-month follow-up, priapism had not recurred, though erectile dysfunction developed.
Conclusion
This case highlights a rare but serious complication of kidney transplantation under general anesthesia, potentially linked to propofol. Timely escalation from aspiration to surgical shunting is crucial in persistent cases to prevent long-term sequelae.
{"title":"Recurrent Priapism After Living Donor Kidney Transplantation Requiring Bilateral T-Shunt Procedure: A Case Report","authors":"Hiroto Kishino, Toru Sugihara, Takuya Iwaki, Sho Nishida, Kyoko Minamisono, Takehiro Oyama, Satoshi Ando, Kimihiko Moriya, Daiki Iwami, Tetsuya Fujimura","doi":"10.1002/iju5.70090","DOIUrl":"https://doi.org/10.1002/iju5.70090","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Priapism is a persistent penile erection lasting > 4 h without sexual stimulation. Ischemic priapism requires urgent management. We report a recurrent ischemic priapism case post-living-donor kidney transplantation necessitating multiple interventions, including bilateral T-shunt procedures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 44-year-old man with end-stage kidney disease from malignant nephrosclerosis and IgA nephropathy underwent living-donor kidney transplantation. On postoperative Day 5, priapism appeared upon catheter removal. Bedside corporal aspiration was initially performed. Recurrence prompted Winter's shunt on Day 6. Blood gas analysis confirmed ischemic priapism. On Day 7, further recurrence required bilateral T-shunts, resolving the condition. Propofol, used during anesthesia, was suspected as the cause. At the 6-month follow-up, priapism had not recurred, though erectile dysfunction developed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This case highlights a rare but serious complication of kidney transplantation under general anesthesia, potentially linked to propofol. Timely escalation from aspiration to surgical shunting is crucial in persistent cases to prevent long-term sequelae.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 6","pages":"567-570"},"PeriodicalIF":0.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70090","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We present a rare case of tuberculous retroperitoneal lymphadenitis after kidney transplantation that was difficult to diagnose and treat.
Case Presentation
A 52-year-old man who received a kidney transplantation from his wife presented with right lower quadrant pain. Computed tomography (CT) scan revealed multiple enlarged retroperitoneal lymph nodes, which later formed abscesses. From the positive Mycobacterium tuberculosis polymerase chain reaction test and smear in the drainage fluid, he was diagnosed with tuberculosis. Despite treatment with antituberculosis drugs, the abscesses increased, and he was treated by open drainage. He showed gradual clinical improvement and was discharged 9 weeks after hospitalization. While an abscess around the pancreatic tail remained, he was in remission, and antituberculosis drugs were terminated 404 days after initiation. He has gone 1 year without recurrence.
Conclusion
Tuberculous lymphadenitis after kidney transplantation is a rare condition but should be kept in mind for accurate diagnosis.
{"title":"Tuberculous Retroperitoneal Lymphadenitis After Kidney Transplantation That Was Difficult to Diagnose and Treat: A Case Report","authors":"Ryota Nakayasu, Yuki Kita, Yuki Teramoto, Kenji Nakamura, Toru Sakatani, Kimihiko Masui, Takayuki Goto, Ryoichi Saito, Takashi Kobayashi","doi":"10.1002/iju5.70076","DOIUrl":"https://doi.org/10.1002/iju5.70076","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>We present a rare case of tuberculous retroperitoneal lymphadenitis after kidney transplantation that was difficult to diagnose and treat.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 52-year-old man who received a kidney transplantation from his wife presented with right lower quadrant pain. Computed tomography (CT) scan revealed multiple enlarged retroperitoneal lymph nodes, which later formed abscesses. From the positive <i>Mycobacterium tuberculosis</i> polymerase chain reaction test and smear in the drainage fluid, he was diagnosed with tuberculosis. Despite treatment with antituberculosis drugs, the abscesses increased, and he was treated by open drainage. He showed gradual clinical improvement and was discharged 9 weeks after hospitalization. While an abscess around the pancreatic tail remained, he was in remission, and antituberculosis drugs were terminated 404 days after initiation. He has gone 1 year without recurrence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Tuberculous lymphadenitis after kidney transplantation is a rare condition but should be kept in mind for accurate diagnosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 6","pages":"558-562"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70076","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mao Saito, Hiromichi Katayama, Satoko Sato, Sota Oguro, Takuro Goto, Yohei Satake, Takuma Sato, Yoshihide Kawasaki, Naoki Kawamorita, Akihiro Ito
Introduction
Spermatocytic tumor is rare, accounting for approximately 1% of all testicular neoplasms. It is clinically and pathologically distinct from classical seminoma and typically presents as a unilateral, slow-growing mass in older men.
Case Presentation
A 54-year-old man presented with painless bilateral scrotal swelling. Imaging revealed heterogeneous masses in both testes, and laboratory findings were within normal limits. Left high orchiectomy revealed polygonal cells with clear cytoplasm, initially suggesting seminoma. Given the patient's age and histological features, immunohistochemistry was performed. A right high orchiectomy was subsequently conducted. Both tumors were diagnosed as spermatocytic tumors based on SALL4 positivity and PLAP, c-kit, and Vimentin negativity. The patient developed postoperative hypogonadism and began testosterone replacement therapy. No recurrence was observed during 1-year follow-up.
Conclusion
This rare case of synchronous bilateral spermatocytic tumor highlights the importance of considering this diagnosis in older men with bilateral testicular masses. Immunohistochemistry is essential for accurate identification.
{"title":"A Case of Synchronous Bilateral Spermatocytic Tumor","authors":"Mao Saito, Hiromichi Katayama, Satoko Sato, Sota Oguro, Takuro Goto, Yohei Satake, Takuma Sato, Yoshihide Kawasaki, Naoki Kawamorita, Akihiro Ito","doi":"10.1002/iju5.70075","DOIUrl":"https://doi.org/10.1002/iju5.70075","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Spermatocytic tumor is rare, accounting for approximately 1% of all testicular neoplasms. It is clinically and pathologically distinct from classical seminoma and typically presents as a unilateral, slow-growing mass in older men.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 54-year-old man presented with painless bilateral scrotal swelling. Imaging revealed heterogeneous masses in both testes, and laboratory findings were within normal limits. Left high orchiectomy revealed polygonal cells with clear cytoplasm, initially suggesting seminoma. Given the patient's age and histological features, immunohistochemistry was performed. A right high orchiectomy was subsequently conducted. Both tumors were diagnosed as spermatocytic tumors based on SALL4 positivity and PLAP, c-kit, and Vimentin negativity. The patient developed postoperative hypogonadism and began testosterone replacement therapy. No recurrence was observed during 1-year follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This rare case of synchronous bilateral spermatocytic tumor highlights the importance of considering this diagnosis in older men with bilateral testicular masses. Immunohistochemistry is essential for accurate identification.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 6","pages":"553-557"},"PeriodicalIF":0.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70075","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Primary squamous cell carcinoma of the prostate accounts for < 1% of prostate cancers.
Case Presentation
A 70-year-old man with no urinary symptoms and a normal prostate-specific antigen of 0.96 ng/mL was referred for abnormal prostate uptake on positron emission tomography-computed tomography. He was diagnosed with locally advanced squamous cell carcinoma of the prostate with lymph node metastasis. Robot-assisted radical prostatectomy and adjuvant chemoradiotherapy were administered. The patient remained in complete remission at 18 months postoperatively.
Conclusion
Squamous cell carcinoma of the prostate should be suspected based on positron emission tomography-computed tomography prostate uptake. Robot-assisted radical prostatectomy may be feasible for locally advanced squamous cell carcinoma of the prostate; genetic profiling should be considered to identify targeted therapies.
{"title":"Locally Advanced Prostate Squamous Cell Carcinoma Diagnosed Using PET-CT and Treated With Robot-Assisted Radical Prostatectomy","authors":"Masayuki Waki, Akira Fujisaki, Shunya Usami, Kei Muraoka, Yasuhiro Hakamata, Yuka Kanda, Kota Sugiura, Masashi Yoshida, Yoshiro Otsuki, Tatsuaki Yoneda","doi":"10.1002/iju5.70088","DOIUrl":"https://doi.org/10.1002/iju5.70088","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Primary squamous cell carcinoma of the prostate accounts for < 1% of prostate cancers.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 70-year-old man with no urinary symptoms and a normal prostate-specific antigen of 0.96 ng/mL was referred for abnormal prostate uptake on positron emission tomography-computed tomography. He was diagnosed with locally advanced squamous cell carcinoma of the prostate with lymph node metastasis. Robot-assisted radical prostatectomy and adjuvant chemoradiotherapy were administered. The patient remained in complete remission at 18 months postoperatively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Squamous cell carcinoma of the prostate should be suspected based on positron emission tomography-computed tomography prostate uptake. Robot-assisted radical prostatectomy may be feasible for locally advanced squamous cell carcinoma of the prostate; genetic profiling should be considered to identify targeted therapies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":"539-543"},"PeriodicalIF":0.0,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144934824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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