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Treatment of medial tibial stress syndrome using an investigational lower leg brace. A pilot for a randomised controlled trial. 小腿支架治疗胫骨内侧应激综合征的研究。随机对照试验的先导。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-04-28 DOI: 10.1136/bmjinnov-2022-001054
W. McNamara, T. Longworth, Joo Y. Sunwoo, Syed MT Rizvi, Christopha J Knee, Brandi Cole
Objective Medial tibial stress syndrome (MTSS) is common and often difficult to treat. The purpose of this study was to examine the effect of a lower leg brace on MTSS symptoms compared to a placebo. Methods A pilot of a prospective double-blinded randomised placebo-controlled trial conducted in two private sports medicine practices. Included were those with symptomatic MTSS lasting 6 weeks or more. Excluded were those with other lower limb pathologies. Fourteen participants formed the study cohort who wore the brace or placebo. The brace applied counterforce pressure to the musculotendinous junctions of the soleus, compressed periosteum at the distal third of the posteromedial tibia and applied inferomedial torsion to the soleus muscle. Additional treatment modalities were recorded. Participants completed a standardised MTSS Severity Score at 0–6, 8, 12 and 24 weeks and recorded return to full activity. Results The brace group demonstrated a significantly reduced MTSS severity score from 5 to 24 weeks (p<0.03) and had returned to full activity within 5 weeks. MTSS score in the placebo group remained unchanged (p >0.05), all participants experienced MTSS recurrence and none returned to full activity over 24 weeks. Conclusion The lower leg brace demonstrated a reduction in MTSS symptoms from 5 weeks that was sustained over 6 months with a lower rate of MTSS recurrence compared with the placebo. If similar results are seen in a larger cohort, it has potential to benefit patients with MTSS as an adjunct to current treatment modalities. Further investigation regarding efficacy is needed. Trial registration number ACTRN12620000906954.
目的胫骨内侧应激综合征(MTSS)是一种常见且难以治疗的疾病。本研究的目的是研究与安慰剂相比,下肢支架对MTSS症状的影响。方法在两家私人运动医学诊所进行前瞻性双盲随机安慰剂对照试验。包括症状性MTSS持续6周或更长时间的患者。排除有其他下肢病变的患者。14名参与者组成了研究队列,他们佩戴了支架或安慰剂。该支具对比目鱼肌的肌肉肌腱连接处施加反力压力,压迫胫骨后内侧远端三分之一的骨膜,并对比目鱼肌施加内侧间扭转。记录其他治疗方式。参与者在0-6周、8周、12周和24周完成标准化的MTSS严重程度评分,并记录全部活动的恢复情况。结果支架组MTSS严重程度评分从5周到24周显著降低(p0.05),所有参与者都经历了MTSS复发,没有人在24周内恢复完全活动。结论:与安慰剂组相比,下肢支架组5周后MTSS症状减轻,持续6个月以上,MTSS复发率较低。如果在更大的队列中看到类似的结果,它有可能使MTSS患者受益,作为当前治疗方式的辅助。需要进一步研究其疗效。试验注册号ACTRN12620000906954。
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引用次数: 0
Emerging technologies and global health: a systematic review generating bibliometric evidence for innovation management 新兴技术与全球健康:为创新管理提供文献计量证据的系统综述
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-04-07 DOI: 10.1136/bmjinnov-2022-001064
Sheng Wu, Bernardo Mariano Junior
Objective To obtain quantitative evidence for innovation management on Emerging Technologies and Global Health from existing scientific research with a bibliometric approach. Design This study generates quantitative evidence for healthcare innovation policy making, offering new insights: first, innovation quality can be measured through dynamic interactions among key innovation elements; second, as emerging technologies are impacting global health in an interdisciplinary and fast-changing manner, new theories and tools that suit the planetary innovation ecosystem need to be established. The evidence contains two aspects, the intellectual base and the research front. The software used is Citespace V.6.1.R3 and Python. Data source This study scanned the Web of Science Core Collection with an extensive range of research themed around emerging technologies and global health, resulting in a dataset of 9738 items of science literature between 2017 and 2021. Eligibility criteria for selecting studies This dataset contains literature across sciences and social sciences in the form of journal research articles, excluding systematic reviews and surveys. The search includes literature in all languages. Results This study presents the landscape of emerging technology and global health, depicts the quality of innovation, and reveals the innovation trends. It demonstrates the major players and major sources of innovation, captures innovation foci and detects research blanks. Conclusion This bibliometric analysis, which is conducted on scientific research, outlines the quality and impact of innovation in Emerging Technologies and Global Health. It shows the importance of Research and Development for generating quantitative evidence for innovation management policy making.
目的运用文献计量学方法,从现有科学研究中获得新兴技术创新管理与全球健康的定量证据。本研究为医疗卫生创新政策制定提供了量化证据,提供了新的见解:第一,创新质量可以通过关键创新要素之间的动态互动来衡量;第二,随着新兴技术以跨学科和快速变化的方式影响全球卫生,需要建立适合全球创新生态系统的新理论和工具。证据包括知识基础和研究前沿两个方面。软件版本为Citespace V.6.1。R3和Python。本研究扫描了以新兴技术和全球健康为主题的广泛研究的Web of Science Core Collection,得出了2017年至2021年间9738项科学文献的数据集。本数据集包含以期刊研究文章形式出现的跨科学和社会科学文献,不包括系统综述和调查。搜索包括所有语言的文献。结果本研究呈现了新兴技术与全球健康的格局,描绘了创新的质量,揭示了创新的趋势。它展示了创新的主要参与者和主要来源,抓住了创新焦点,发现了研究空白。这项文献计量分析是对科学研究进行的,概述了新兴技术和全球健康创新的质量和影响。这表明了研究与开发对创新管理政策制定提供定量证据的重要性。
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引用次数: 1
Correction: User-centred innovation to advance safe surgery at the point of need: report on development of the SurgiField system 更正:以用户为中心的创新,在需要时推进安全手术:关于SurgiField系统开发的报告
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-02-22 DOI: 10.1136/bmjinnov-2021-000893.corr1
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引用次数: 0
Community engagement self-monitoring (CE-SM) strategy for social innovations in health: pilot implementation in the Philippines 促进卫生领域社会创新的社区参与自我监测战略:在菲律宾试点实施
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2023-01-13 DOI: 10.1136/bmjinnov-2022-001049
Pauline Marie Padilla Tiangco, J. Mier-Alpaño, J. R. B. Cruz, J. Alacapa, Joey J. Escauso, U. Amazigo, B. Halpaap, M. Labarda, N. Juban
The Social Innovation in Health Initiative (SIHI) piloted a community engagement self-monitoring (CE-SM) strategy, where communities were actively engaged in monitoring the implementation and performance of their social innovations to ensure that their objectives were achieved. This strategy aims to empower communities to document processes, understand the factors involved and measure outcomes by developing a community-grounded self-monitoring tool and implementing their own approach. Two community comanaged social innovations were selected. For one innovation, the communities implemented the CE-SM independent of external intervention. For the second, the communities were provided with minimal assistance by SIHI. These communities identified their monitoring indicators and selected local monitors to collect data to assess performance outcomes and document the entire process. Communities chose indicators based on their perceived importance and practicality, while monitors were chosen based on their familiarity with the community. Community leaders’ proactive leadership and community members’ participation contributed significantly to its success. The important role of regular feedback sessions was also emphasised, not only as a means of monitoring progress but also for boosting their morale. The level of external support needed by a community was determined by the scope of the project and the community’s grasp of the strategy. CE-SM has been demonstrated to be a viable strategy when communities realise their capacity to monitor their own projects using an approach they deem fit. It has also enhanced their sense of ownership which could improve the chances of sustaining these initiatives and contribute to more accessible healthcare and services.
保健方面的社会创新倡议试行了一项社区参与自我监测战略,社区积极参与监测其社会创新的实施和绩效,以确保实现其目标。该战略旨在通过开发以社区为基础的自我监测工具和实施自己的方法,使社区能够记录过程,了解所涉及的因素并衡量结果。选择了两个社区管理的社会创新。其中一个创新是,社区独立于外部干预实施CE-SM。第二,SIHI向社区提供了最低限度的援助。这些社区确定了他们的监测指标,并选择了当地监测员来收集数据,以评估绩效结果,并记录整个过程。社区根据其感知的重要性和实用性选择指标,而监测员则根据其对社区的熟悉程度选择。社区领袖的积极领导和社区成员的积极参与对项目的成功起到了重要作用。还强调了定期反馈会议的重要作用,这不仅是监测进展的一种手段,而且也是提高他们士气的一种手段。社区所需的外部支持水平取决于项目的范围和社区对策略的掌握程度。当社区意识到他们有能力使用他们认为合适的方法来监测自己的项目时,CE-SM已被证明是一种可行的战略。它还增强了他们的主人翁意识,这可以提高维持这些举措的机会,并有助于提供更容易获得的保健和服务。
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引用次数: 0
Non-communicable diseases in a time of infection 非传染性疾病在感染的时代
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-12-26 DOI: 10.1136/bmjinnov-2022-000996
Helen Surana
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引用次数: 0
Patient-specific tracheal stoma plug improves quality of life for tracheostomy patients 患者特异性气管造口塞改善气管造口术患者的生活质量
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-12-05 DOI: 10.1136/bmjinnov-2022-001028
K. VanKoevering, Julia Brennen, Rachel Fenberg, Samuel D. Dolphin, Natalia von Windheim, L. Matrka, B. D. De Silva, M. Spector, S. Chinn, P. Choi, Songzhu Zhao, K. Casper, G. Green
Objective Despite being life-saving, tracheostomies carry numerous social, functional and quality of life (QOL) drawbacks. The aim of this study was to design and test the use of small, discrete, customised tracheostomy stoma plugs in patients who are not tracheostomy-dependent during the day, with the overall goals to demonstrate the feasibility of creating these patient-specific devices and obtain preliminary results of impact on QOL. Methods We developed and evaluated a novel patient-specific ‘stoma plug’ to improve the lives of those with tracheostomies who did not have a daytime ventilation requirement. The stoma plug was designed and manufactured using three-dimensional printing for each subject. Measurements of the patient’s fistula were obtained in the clinic and the features of the stoma plug were created to match the fistula and trach tube dimensions. Patients were monitored for any changes in their eligibility status and for complications associated with using the ‘stoma plug’. A survey questionnaire examining multiple QOL domains was performed predevice and at 1 and 6 months of use. Results Devices were designed and produced for 35 patients enrolled across two institutions. The survey results demonstrate statistically significant improvement in quality-of-life scores (p<0.05) in all six domains queried (Overall QOL, voice strength, voice clarity, water tolerance, swallowing and breathing) with substantial improvements in social isolation and skin irritation reported. Conclusion Our study demonstrates that a patient specific device can be created to ameliorate many of the drawbacks associated with a tracheostomy tube, with the potential to revolutionise tracheostomy care.
目的:尽管气管切开术可以挽救生命,但在社会、功能和生活质量(QOL)方面存在许多缺陷。本研究的目的是设计和测试在白天不依赖气管造口术的患者中使用小型、离散、定制的气管造口塞,总体目标是证明制造这些患者专用设备的可行性,并获得对生活质量影响的初步结果。方法:我们开发并评估了一种新型的患者特异性“造口塞”,以改善气管造口术患者的生活,这些患者不需要日间通气。使用三维打印技术为每个受试者设计和制造造口塞。在临床获得了患者瘘管的测量,并创建了瘘塞的特征以匹配瘘管和气管管的尺寸。监测患者的适格状态的任何变化以及与使用“造口塞”相关的并发症。在器械前和使用1个月和6个月时进行了一份调查问卷,检查了多个生活质量领域。研究人员为两家机构的35名患者设计和生产了器械。调查结果显示,在所调查的所有六个领域(总体生活质量、声音强度、声音清晰度、水耐受性、吞咽和呼吸)中,生活质量评分均有统计学显著改善(p<0.05),社会隔离和皮肤刺激也有实质性改善。结论:我们的研究表明,可以创建一种患者专用设备来改善与气管造口管相关的许多缺点,具有彻底改变气管造口护理的潜力。
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引用次数: 0
Effectiveness of an anti-fog polymer coating in protective eyewear: a blinded, randomised controlled cross-over trial with healthcare providers in an emergency department setting 防护眼镜中防雾聚合物涂层的有效性:一项与急诊科设置的医疗保健提供者进行的盲法、随机对照交叉试验
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-11-03 DOI: 10.1136/bmjinnov-2022-000962
Yonatan G. Keschner, A. Raja, J. Margolin, Hui Zheng, K. Olson
Background Eye protection is a mandatory component of the personal protective equipment in healthcare settings, especially for suspected or confirmed cases of COVID-19 and during aerosolising procedures. Fogging of protective eyewear is a frequent problem experienced by providers. The hydrophilic property of a sulfonated polymer, BiaXam, may be able to decrease fogging through wicking moisture from the lens. In this study, we tested the anti-fogging properties of this polymer when applied to protective eyewear. Methods An investigator-initiated prospective, randomised, single-blinded cross-over study was conducted in an emergency department in a large, tertiary care hospital. Participants were blinded and randomised first to either a pair of anti-fog coated or uncoated eyewear, and then to the alternative pair after 2 hours. Study participants completed an identical survey at the end of each 2-hour period. Results 50 emergency medicine healthcare providers were enrolled and 48 completed the study. Results demonstrated a significant difference in fogging between the coated and uncoated eyewear, as 81% of the participants reported fogging of the uncoated lenses and only 55% of the participants reported fogging in the coated pair (p=0.0029). Participants reported that the uncoated lenses fogged two times as frequently on a 10-point Likert scale (4.5±3.3 vs 2.1±2.5; p<0.0001). Subgroup analysis of participants who wore only a surgical mask demonstrated even more efficacious results with coated eyewear. Conclusion Overall, sulfonated polymer-coated eyewear improved provider visualisation, user experience and perceived mitigation of potential medical errors.
护眼是医疗机构中个人防护装备的强制性组成部分,特别是对于COVID-19疑似或确诊病例以及在雾化过程中。护目镜起雾是供应商经常遇到的问题。磺化聚合物BiaXam的亲水性可以通过吸干透镜中的水分来减少起雾。在这项研究中,我们测试了这种聚合物在防护眼镜上的防雾性能。方法在一家大型三级医院的急诊科进行了一项研究者发起的前瞻性、随机、单盲交叉研究。参与者被盲法随机分为两组,一组戴有防雾涂层的眼镜,另一组戴无防雾涂层的眼镜,两小时后再戴另一组。研究参与者在每两小时结束时完成一份相同的调查。结果纳入50名急诊医疗服务提供者,48名完成研究。结果表明,涂层眼镜和未涂层眼镜在起雾方面存在显著差异,81%的参与者报告未涂层眼镜起雾,而只有55%的参与者报告涂层眼镜起雾(p=0.0029)。参与者报告说,未涂覆的镜片在10分李克特量表(4.5±3.3 vs 2.1±2.5;p < 0.0001)。对只戴外科口罩的参与者的亚组分析表明,戴涂层眼镜的结果更有效。总体而言,磺化聚合物涂层眼镜改善了提供者的可视化,用户体验和潜在医疗差错的感知缓解。
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引用次数: 0
Novel ‘half-and-half’ design of staining jars for comparative assessment of stains 新颖的“半对半”染色罐设计,用于比较评估污渍
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-11-01 DOI: 10.1136/bmjinnov-2022-000983
S. Sachdev, T. Chettiankandy
© Author(s) (or their employer(s)) 2022. No commercial reuse. See rights and permissions. Published by BMJ. INTRODUCTION At present, Coplin jars are used universally for histological staining. They are grooved glass jars which allow microscopic slides to stand separated while staining procedure. They were invented by William Coplin in 1897 and remain in use to date. Except for a few modifications such as use of plastic materials, or screwcapping to avoid evaporation or contamination, the design of Coplin jars has remained mostly unchanged. Many times, situations arise in histopathological laboratories wherein multiple special stains are to be applied on the tissue sections for histochemical confirmation of the nature of cells or material. The scenario is fairly common in researches that compare two or more histological stains. Certain study designs also revolve around comparing the effect of fixation or embedding on staining characteristics. Demonstrating suitability of histological stains in detecting microbes, pigments, or tissue elements such as muscle, cartilage, etc aids in making the diagnostic pathological procedures more accurate and efficient. In such scenarios, the extent of materials such as microscopic slides, cover slips, staining dyes and other chemicals required for the procedures correspond to the number of samples to be stained. The need may not seem significant in routine cases, but the financial toll is amplified exponentially when a large number of samples are involved in studies. Many laboratories, particularly in lowincome and middleincome countries, are not able to afford such exuberant expenditure and are ultimately unable to conduct such largescale comparative studies due to nonfeasibility. They either refrain from conducting the study or select a smaller sample size. A smaller sample size ultimately makes the finals results of their study less valid. The chemicals and materials required for research may also be difficult to procure at times. The problem is fairly common in rural areas of lowincome and middleincome countries, such as India. The problem was even further amplified in COVID19 pandemic, wherein much of the funds were focused on countering the pandemic. There was a decrease Summary box
©作者(或其雇主)2022。禁止商业重用。请参阅权利和权限。英国医学杂志出版。目前普遍采用Coplin罐进行组织学染色。它们是有槽的玻璃罐,在染色过程中可以使显微镜载玻片分离。它们是由威廉·科普林于1897年发明的,至今仍在使用。除了一些修改,如使用塑料材料,或螺旋盖,以避免蒸发或污染,Coplin罐的设计基本保持不变。很多时候,在组织病理学实验室中,需要在组织切片上应用多个特殊的染色剂来组织化学确认细胞或材料的性质。这种情况在比较两种或更多组织学染色的研究中相当常见。某些研究设计也围绕着比较固定或包埋对染色特征的影响。证明组织学染色在检测微生物、色素或组织元素(如肌肉、软骨等)方面的适用性,有助于使病理诊断过程更加准确和有效。在这种情况下,材料的程度,如显微镜载玻片,盖玻片,染色染料和其他化学品所需的程序对应于样品染色的数量。在常规情况下,这种需求似乎并不重要,但当研究涉及大量样本时,经济代价就会成倍增加。许多实验室,特别是低收入和中等收入国家的实验室,无法负担如此庞大的支出,由于不可行,最终无法进行如此大规模的比较研究。他们要么避免进行研究,要么选择较小的样本量。较小的样本量最终会使他们研究的最终结果不那么有效。研究所需的化学品和材料有时也很难获得。这个问题在印度等低收入和中等收入国家的农村地区相当普遍。在2019冠状病毒病大流行期间,这一问题进一步加剧,其中大部分资金都用于应对这一流行病。有一个减少摘要框
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引用次数: 0
SAFER framework for moving forward on the medical device right to repair 推进医疗器械维修权的更安全框架
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-10-26 DOI: 10.1136/bmjinnov-2022-000936
Shuhan He, D. Lai, Grace Jin, Jarone Lee
Across various industries, the right to repair (RTR) movement has gained momentum as more than 20 states have proposed RTR laws to expand access to repair of consumer products. Medical device equipment shortages during the COVID-19 pandemic demonstrated that stronger repair mechanisms are necessary for the US health system to become more efficient, affordable and sustainable. We propose a 5-point SAFER framework including safety and security, adaptability, fiscal, environmental and regulatory factors for consideration in implementing medical device RTR. The healthcare community can help advance RTR legislation in a manner that serves our patients and healthcare system best.
在各个行业中,随着20多个州提出RTR法律以扩大消费者产品维修的机会,维修权(RTR)运动获得了动力。COVID-19大流行期间医疗器械设备短缺表明,美国卫生系统需要更强大的修复机制,以提高效率、负担得起和可持续性。在实施医疗器械RTR时,我们提出了一个包括安全和安保、适应性、财政、环境和监管因素在内的五点SAFER框架。医疗保健社区可以帮助推进RTR立法,以最好地服务于我们的患者和医疗保健系统。
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引用次数: 1
Implementation of a community-based referral project to improve access to emergency obstetric and newborn care in Rohingya population during COVID-19 pandemic in Bangladesh. 在孟加拉国实施基于社区的转诊项目,以改善罗兴亚人在COVID-19大流行期间获得紧急产科和新生儿护理的机会。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-09-29 DOI: 10.1136/bmjinnov-2021-000831
Mrittika Barua, Avijit Saha, Srizan Chowdhury, Sayantan Chowdhury, Stenly Hely Sajow, Malabika Sarker

Introduction: The delay in seeking emergency obstetric care leads to significant maternal morbidity and mortality and can worsen during pandemics, especially in humanitarian conflict settings with low uptake of obstetric services. To mitigate the challenges related to the second delay caused by lack of transport in the COVID-19 pandemic, the organisation United Nations Population Fund implements a community-based referral project called Referral Hub in the Rohingya refugee population in Bangladesh. The objective of the paper is to describe the implementation process of the Referral hub and present clients' utilisation and perception of the service.

Methods: Findings from part of a larger mixed-method study, the analysis of the standard operating protocol of the intervention, secondary data of routine utilisation of the 12 referral hubs between January and August 2020, 21 key informant interviews and a community survey among 100 pregnant women are presented in this paper.

Results: The findings show an increasing trend in the referral hub utilisation and a strong recommendation of the service.

Conclusion: Due to a robust referral mechanism by collaborating with the community and engaging accessible and free of cost transport service, the intervention has high potential to improve access to facility care in low-resource and humanitarian contexts, especially during pandemics.

导言:寻求紧急产科护理的延误导致产妇发病率和死亡率很高,在大流行病期间可能会恶化,特别是在产科服务使用率低的人道主义冲突环境中。为减轻因COVID-19大流行期间交通不便造成的第二次延误所带来的挑战,联合国人口基金组织在孟加拉国罗兴亚难民人口中实施了一个名为转诊中心的社区转诊项目。本文的目的是描述转诊中心的实施过程,并介绍客户对服务的利用和感知。方法:本文介绍了一项大型混合方法研究的部分结果、对干预标准操作方案的分析、2020年1月至8月期间12个转诊中心常规利用的次要数据、21个关键信息提供者访谈和对100名孕妇的社区调查。结果:调查结果显示,在转诊中心的利用和服务的强烈推荐增加的趋势。结论:由于通过与社区合作和采用无障碍和免费运输服务建立了强有力的转诊机制,该干预措施在资源匮乏和人道主义情况下,特别是在大流行病期间,具有很大的潜力改善获得设施护理的机会。
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引用次数: 2
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