Pub Date : 2022-01-01DOI: 10.1136/bmjinnov-2021-000739
E. Harris, K. Shelley, Thenjiwe Sisimayi, Catherine Wandie, Cal Bruns
Objective For adolescent girls and young women (AGYW) in sub-Saharan Africa, oral tenofovir‐based pre‐exposure prophylaxis (commonly referred to as PrEP) provides a user-controlled HIV prevention method, critical to addressing their HIV risk and unmet prevention needs. Addressing the gap between clinical and real-world PrEP efficacy requires new approaches, such as ‘V’. ‘V’ reframes PrEP from medicine to self-care that is as easy to use as a young women’s favourite fashion or beauty brand. This article describes how human-centred design (HCD) was used to adapt the ‘V’ brand and service delivery strategy for implementation in Zimbabwe from its development via formative research in South Africa. Methods Following literature review, stakeholder analysis and landscaping, the ‘V’ brand and service delivery strategy were assessed through participatory immersion sessions with 152 participants in four Zimbabwe districts. Insights were synthesised across learning questions: What do AGYW and health workers think about ‘V’?; Which of the ‘V’ materials are most acceptable and relevant for Zimbabwe?; What adaptations are necessary for the selected ‘V’ materials for Zimbabwe?; and How should the selected ‘V’ assets be integrated? Results The ‘V’ innovative design principles—delightfully bold branding, a discreet starter kit and user-friendly materials that put young women in control of educating others—remained resonant. Feasible modifications were identified to adapt the ‘V’ brand and service delivery strategy to suit the local context. Conclusion ‘V’ delivers a ‘delightfully discreet’ approach that puts AGYW in charge of preventing HIV. The resonance of the core ‘V’ design concepts demonstrates how HCD can be applied to reframe PrEP as a product category (ie, from a stigmatising medicine to empowering self-care).
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Pub Date : 2021-12-03DOI: 10.1136/bmjinnov-2021-000790
G. Messina, D. Amodeo, A. Corazza, N. Nante, G. Cevenini
Introduction Surface disinfection is one of the key points to reduce the risk of transmission both in healthcare and other public spaces. A novel UV-chip disinfection technology is presented. Technological, photonic and microbiocidal characteristics are evaluated taking as reference an ultraviolet-C (UV-C) LED source of equivalent radiant power. Methods The UV chip has a circular radiating surface with a diameter of 1.3 cm, emitting UV cold light at about 5 mW and driven current of about 80 µA. Four bacterial strains were used to conduct the microbiological tests at 4°C and 60°C to evaluate the bactericidal performance of the two technologies under the same operating conditions. Results Spectral differences were found between the UV-C LED and the chip, with an emission curve strictly around 280 nm and a broader band centred around 264 nm, respectively. Between-technology microbiological inactivation levels were comparable, achieving total abatement (99.999%) in 8 min at 7.5 cm. Discussion The UV chip exhibits unique properties that make it applicable in some specific contexts, where UV-C LEDs present the most critical issues. Besides, it is portable and exhibits a broad spectrum of UV wavelengths with a peak where the maximum microbiocidal efficacy occurs. Important issues to be addressed to improve this technology are the high voltage management and the too low energy efficiency. Conclusion This cold emission technology is virtually unaffected by changes in ambient temperature and is particularly useful in short-distance applications. Recent developments in technology are moving towards a progressive increase in the chip’s radiant power.
无论是在卫生保健场所还是其他公共场所,表面消毒都是降低传播风险的关键之一。提出了一种新型紫外芯片消毒技术。以等效辐射功率的紫外- c (UV-C) LED光源为参考,对其工艺、光子和杀菌特性进行了评价。方法紫外芯片采用直径1.3 cm的圆形辐射表面,发射功率约为5 mW的紫外冷光,驱动电流约为80µa。采用4株菌株在4℃和60℃条件下进行微生物学试验,评价两种工艺在相同操作条件下的杀菌性能。结果UV-C LED与芯片在光谱上存在差异,发射曲线严格在280 nm附近,而以264 nm为中心的波段较宽。两种技术之间的微生物失活水平是相当的,在7.5 cm处8分钟内达到了99.999%的总减少。UV芯片具有独特的性能,使其适用于某些特定的环境,其中UV- c led提出了最关键的问题。此外,它是便携式的,具有广谱的紫外线波长,在峰值处出现最大的杀微生物效果。改进该技术需要解决的重要问题是高电压管理和过低的能量效率。这种冷发射技术几乎不受环境温度变化的影响,在短距离应用中特别有用。最近的技术发展正朝着逐步提高芯片的辐射功率的方向发展。
{"title":"Analysis of the physical and microbiocidal characteristics of an emerging and innovative UV disinfection technology","authors":"G. Messina, D. Amodeo, A. Corazza, N. Nante, G. Cevenini","doi":"10.1136/bmjinnov-2021-000790","DOIUrl":"https://doi.org/10.1136/bmjinnov-2021-000790","url":null,"abstract":"Introduction Surface disinfection is one of the key points to reduce the risk of transmission both in healthcare and other public spaces. A novel UV-chip disinfection technology is presented. Technological, photonic and microbiocidal characteristics are evaluated taking as reference an ultraviolet-C (UV-C) LED source of equivalent radiant power. Methods The UV chip has a circular radiating surface with a diameter of 1.3 cm, emitting UV cold light at about 5 mW and driven current of about 80 µA. Four bacterial strains were used to conduct the microbiological tests at 4°C and 60°C to evaluate the bactericidal performance of the two technologies under the same operating conditions. Results Spectral differences were found between the UV-C LED and the chip, with an emission curve strictly around 280 nm and a broader band centred around 264 nm, respectively. Between-technology microbiological inactivation levels were comparable, achieving total abatement (99.999%) in 8 min at 7.5 cm. Discussion The UV chip exhibits unique properties that make it applicable in some specific contexts, where UV-C LEDs present the most critical issues. Besides, it is portable and exhibits a broad spectrum of UV wavelengths with a peak where the maximum microbiocidal efficacy occurs. Important issues to be addressed to improve this technology are the high voltage management and the too low energy efficiency. Conclusion This cold emission technology is virtually unaffected by changes in ambient temperature and is particularly useful in short-distance applications. Recent developments in technology are moving towards a progressive increase in the chip’s radiant power.","PeriodicalId":53454,"journal":{"name":"BMJ Innovations","volume":"54 1","pages":"21 - 28"},"PeriodicalIF":2.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87765120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}