Pub Date : 2022-06-28DOI: 10.4274/mjima.galenos.2022.2022.32
S. Ghasemi, S. Shoja, Farzad Mazloomirad, M. A. Ghatee, Fatemeh Rashidpoor, S. Khoramrooz, S. Khosravani, A. Sharifi
{"title":"Prevalence of Aminoglycoside and Carbapenemase Resistance Genes and Biofilm Formation among Clinical Isolates of Acinetobacter baumannii in Iran","authors":"S. Ghasemi, S. Shoja, Farzad Mazloomirad, M. A. Ghatee, Fatemeh Rashidpoor, S. Khoramrooz, S. Khosravani, A. Sharifi","doi":"10.4274/mjima.galenos.2022.2022.32","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2022.32","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"35 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76110086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-16DOI: 10.4274/mjima.galenos.2022.2022.26
A. Altıntop Geçkil, Isilay Gokce Benk, Sukru Aydin, Mehmet Akçiçek
Introduction: This study investigates the relationship between the viral load calculated from oropharyngeal/nasopharyngeal swabs at diagnosis and the laboratory parameters and radiological findings in patients with Coronavirus disease-2019 (COVID-19).Materials and Methods: Sixty-seven patients who were positive for severe acute respiratory syndrome-coronavirus-2 via quantitative reverse transcription-polymerase chain reaction (qPCR) from their oropharyngeal/nasopharyngeal swabs and admitted to Malatya Turgut Ozal University Hospital were included in the study. Demographic data, laboratory parameters, and the severity of thorax computed tomography findings were recorded. The relationship between the viral load and these data was compared.Results: The mean age of the patients was 63.4 +/- 9.8 years, mean body mass index (BMI) was 28.6 +/- 5.4 kg/m2, and mean cycle threshold (Ct) values were 21.4 +/- 5.2 cycles. No correlation was found between Ct value and gender, age, and BMI. There was a significant relationship between radiological severity and Ct value, age, and gender. There was a significant correlation between the Ct value and C-reactive protein, leukocyte, neutrophil, lymphocyte, neutrophil-lymphocyte ratio, ferritin, albumin, and calcium levels. In contrast, no significant correlation was found betweenConclusion: The viral load amount shown by PCR during the early period predicts the condition of the patient's lung in the advanced immunological phase. The Ct value can be an independent factor for evaluating the patient's radiological and biochemical status.
{"title":"The Relationship Between Viral Load and Laboratory Values and Radiological Findings in COVID-19 Patients","authors":"A. Altıntop Geçkil, Isilay Gokce Benk, Sukru Aydin, Mehmet Akçiçek","doi":"10.4274/mjima.galenos.2022.2022.26","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2022.26","url":null,"abstract":"Introduction: This study investigates the relationship between the viral load calculated from oropharyngeal/nasopharyngeal swabs at diagnosis and the laboratory parameters and radiological findings in patients with Coronavirus disease-2019 (COVID-19).Materials and Methods: Sixty-seven patients who were positive for severe acute respiratory syndrome-coronavirus-2 via quantitative reverse transcription-polymerase chain reaction (qPCR) from their oropharyngeal/nasopharyngeal swabs and admitted to Malatya Turgut Ozal University Hospital were included in the study. Demographic data, laboratory parameters, and the severity of thorax computed tomography findings were recorded. The relationship between the viral load and these data was compared.Results: The mean age of the patients was 63.4 +/- 9.8 years, mean body mass index (BMI) was 28.6 +/- 5.4 kg/m2, and mean cycle threshold (Ct) values were 21.4 +/- 5.2 cycles. No correlation was found between Ct value and gender, age, and BMI. There was a significant relationship between radiological severity and Ct value, age, and gender. There was a significant correlation between the Ct value and C-reactive protein, leukocyte, neutrophil, lymphocyte, neutrophil-lymphocyte ratio, ferritin, albumin, and calcium levels. In contrast, no significant correlation was found betweenConclusion: The viral load amount shown by PCR during the early period predicts the condition of the patient's lung in the advanced immunological phase. The Ct value can be an independent factor for evaluating the patient's radiological and biochemical status.","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"37 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90536624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-16DOI: 10.4274/mjima.galenos.2022.2021.27
Melike Yaşar-Duman, C. Çavuşoğlu, I. Altuğlu, A. Zeytinoglu, Ayşe Deni Gökengi, Tansu Gülbahar Aydoğan, M. Orman
{"title":"Evaluation of the Performance of QuantiFERON-TB Gold Plus Assay in HIV Infection","authors":"Melike Yaşar-Duman, C. Çavuşoğlu, I. Altuğlu, A. Zeytinoglu, Ayşe Deni Gökengi, Tansu Gülbahar Aydoğan, M. Orman","doi":"10.4274/mjima.galenos.2022.2021.27","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2021.27","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"95 4","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72452197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-16DOI: 10.4274/mjima.galenos.2022.2022.28
Esra Yildirim Servi, M. Uzun
{"title":"Candida auris: Microbiological Characteristics and Laboratory Diagnosis of the Hidden Pathogen","authors":"Esra Yildirim Servi, M. Uzun","doi":"10.4274/mjima.galenos.2022.2022.28","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2022.28","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"40 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85488946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-12DOI: 10.4274/mjima.galenos.2022.2021.23
A. Bahar, Yasemin Ekim, S. Uysal, M. Ç. Sönmezer, Dolunay Gülmez, Sevgen Çeli̇k Önder, M. Onur, S. Arıkan Akdağlı, A. Inkaya, D. Inan, S. Ünal
{"title":"A Multidisciplinary Approach to Opportunistic Infections in a Late-presenter Person Living with HIV","authors":"A. Bahar, Yasemin Ekim, S. Uysal, M. Ç. Sönmezer, Dolunay Gülmez, Sevgen Çeli̇k Önder, M. Onur, S. Arıkan Akdağlı, A. Inkaya, D. Inan, S. Ünal","doi":"10.4274/mjima.galenos.2022.2021.23","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2021.23","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"82 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74864359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-12DOI: 10.4274/mjima.galenos.2022.2021.25
B. Başpınar, İ. Güven, İ. Yüksel
{"title":"Outcomes of COVID-19 in Patients with Inflammatory Bowel Disease: A Tertiary Center Experience","authors":"B. Başpınar, İ. Güven, İ. Yüksel","doi":"10.4274/mjima.galenos.2022.2021.25","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2021.25","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"75 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80573257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-12DOI: 10.4274/mjima.galenos.2022.2021.24
Ayşin Kılınç Toker, Duygu Çerçioğlu Özdemir, E. Eren, Ayşe Turunç Özdemir, Azade Kanat, I. Çelik, Ibrahim Toker
Introduction: The Coronavirus disease-2019 (COVID-19) pandemic that started over two years ago has led to high mortality and morbidity. Vaccine studies have been initiated worldwide to end the pandemic, and the CoronaVac (R) vaccine was first administered to healthcare workers at high risk of COVID-19 in Turkey. In our study, we aimed to investigate serum antibody levels after vaccination. Materials and Methods: Volunteer healthcare workers without COVID-19 disease who received two doses of CoronaVac (R) vaccine 28 days apart and were at least 14 days after the last dose of vaccine were included in this study. Assessment of antibodies against Severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) in blood samples from participants was performed using the Elecsys (R) anti-SARS-CoV-2 electrochemiluminescence immunoassay. Samples with a cut-off index (COI) (COI;signal sample/cut-off) <1.0 were considered negative;whereas samples with COI >= 1.0 were deemed positive. Results: A total of 269 healthcare workers, 168 women (62.5%), were included in our study. The mean age of the participants was 37.7 +/- 8.6 (minimum-maximum: 21-62). Antibody levels were positive in 188 (69.9%) of the participants. The median antibody level was 9.2 COI (interquartile ranges=3-34.7). In terms of mean age, the mean age of participants with negative antibodies was higher with a statistically significant difference (p=0.001). The antibody positivity rate of women was higher than that of men (p<0.001). No statistically significant association was found between the time elapsed after vaccination, presence of comorbidities, development of post-vaccine side effects, and antibody levels. It was found that one or more side effects developed in 45.7% of the participants after vaccination. Conclusion: Our study showed that seropositivity developed significantly in healthcare workers after the CoronaVac (R) vaccine. It emphasizes the importance of maintaining infection prevention and control measures and administering the SARS-CoV-2 vaccine for healthcare workers at high risk.
{"title":"Anti-nucleocapsid Antibody Response After Two Doses of CoronaVac® Among Healthcare Workers","authors":"Ayşin Kılınç Toker, Duygu Çerçioğlu Özdemir, E. Eren, Ayşe Turunç Özdemir, Azade Kanat, I. Çelik, Ibrahim Toker","doi":"10.4274/mjima.galenos.2022.2021.24","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2021.24","url":null,"abstract":"Introduction: The Coronavirus disease-2019 (COVID-19) pandemic that started over two years ago has led to high mortality and morbidity. Vaccine studies have been initiated worldwide to end the pandemic, and the CoronaVac (R) vaccine was first administered to healthcare workers at high risk of COVID-19 in Turkey. In our study, we aimed to investigate serum antibody levels after vaccination. Materials and Methods: Volunteer healthcare workers without COVID-19 disease who received two doses of CoronaVac (R) vaccine 28 days apart and were at least 14 days after the last dose of vaccine were included in this study. Assessment of antibodies against Severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) in blood samples from participants was performed using the Elecsys (R) anti-SARS-CoV-2 electrochemiluminescence immunoassay. Samples with a cut-off index (COI) (COI;signal sample/cut-off) <1.0 were considered negative;whereas samples with COI >= 1.0 were deemed positive. Results: A total of 269 healthcare workers, 168 women (62.5%), were included in our study. The mean age of the participants was 37.7 +/- 8.6 (minimum-maximum: 21-62). Antibody levels were positive in 188 (69.9%) of the participants. The median antibody level was 9.2 COI (interquartile ranges=3-34.7). In terms of mean age, the mean age of participants with negative antibodies was higher with a statistically significant difference (p=0.001). The antibody positivity rate of women was higher than that of men (p<0.001). No statistically significant association was found between the time elapsed after vaccination, presence of comorbidities, development of post-vaccine side effects, and antibody levels. It was found that one or more side effects developed in 45.7% of the participants after vaccination. Conclusion: Our study showed that seropositivity developed significantly in healthcare workers after the CoronaVac (R) vaccine. It emphasizes the importance of maintaining infection prevention and control measures and administering the SARS-CoV-2 vaccine for healthcare workers at high risk.","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"63 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81125336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-09DOI: 10.4274/mjima.galenos.2022.2021.18
Abubakar Suleiman Kankara, U. A. Dutsinma, I. Yusuf
{"title":"Antimicrobial Activities of Piperacillin-Tazobactam plus oxyimino-cephalosporins and Gentamicin against Extensively Drug Resistant Non-Carbapenemase producing Enterobacteriaceae Isolated from Immune-compromised Patients in a Nigerian Hospital","authors":"Abubakar Suleiman Kankara, U. A. Dutsinma, I. Yusuf","doi":"10.4274/mjima.galenos.2022.2021.18","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2021.18","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"88 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81937307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-09DOI: 10.4274/mjima.galenos.2022.2021.17
Emsal Aydın, Nihal Türkmen Türker, A. Şahin
{"title":"A Case of Mild Encephalitis/encephalopathy with a ReversibleSplenial Lesion (MERS)Caused by Hantavirus","authors":"Emsal Aydın, Nihal Türkmen Türker, A. Şahin","doi":"10.4274/mjima.galenos.2022.2021.17","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2021.17","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"26 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83641817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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