Pub Date : 2022-03-09DOI: 10.4274/mjima.galenos.2022.2021.22
M. Çabalak, Tayibe Bal, F. Turgut
{"title":"Investigation of the Effects of Antivirals Used for HIV Treatment on Renal Function","authors":"M. Çabalak, Tayibe Bal, F. Turgut","doi":"10.4274/mjima.galenos.2022.2021.22","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2021.22","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75873833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-09DOI: 10.4274/mjima.galenos.2022.2021.19
Hasan Yeşilağaç, H. Alışkan, H. Gümüş, İ. Ödemiş, Zuhal EKİCİ ÜNSAL
Introduction: Since the Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) first emerged in Wuhan, on 12 December 2019, it has spread rapidly across the world and developed into a pandemic. As healthcare workers are frequently in contact with Coronavirus disease-2019 (COVID-19) patients, they can be affected more often than the general population. In this study we aimed to investigate the SARS-CoV-2 seroprevalence and the IgG antibody levels among healthcare workers who frequently encountered COVID-19 patients in our hospital.Materials and Methods: In total, 182 healthcare workers were identified from database and their data was retrospectively analyzed. Participants with previous PCR positivity, pregnant, autoimmune disease history or immunosuppressive treatment history were excluded. Participants were grouped depending on their frequency of contact with COVID-19 patients (high and medium risk). All the samples were tested simultaneously for anti-SARS-CoV-2-IgG antibodies by the ELISA method. A chi-square test was used to compare categorical variables. A t-test and an ANOVA test were carried out to where appropriate.Results: Serological testing of 182 HCWs exposed to SARS-CoV-2 patients illustrated that 13.2% of them (24 out of 182) might have experienced an asymptomatic or subclinical SARS-CoV-2 infection. High risk participants, anosmia, and ageusia were statistically significant risk factors. The rate of detection of antibody positivity among doctors (p=0.030) and patients with anosmia, and ageusia (p=0.047) were found significantly higher than the others. In addition, SARS-CoV-2 antibody ratio results were found significantly higher in the groups of high risk participants (p=0.046), patients with clinical signs (p=0.008), myalgia (p=0.039), anosmia, and ageusia (p=0.025), respectively.Conclusion: Our study showed that serological testing is useful for determining asymptomatic or subclinical infections prevelance of SARS-CoV-2 among those with close contact with COVID-19 patients. Serological tests can be helpful determining the prevelance COVID-19 infection, especially among the HCWs.
{"title":"Evaluation of IgG Neutralizing Antibodies to SARS-CoV-2 Among Healthcare Workers Who Frequently Encountered COVID-19 Patients in Our Hospital","authors":"Hasan Yeşilağaç, H. Alışkan, H. Gümüş, İ. Ödemiş, Zuhal EKİCİ ÜNSAL","doi":"10.4274/mjima.galenos.2022.2021.19","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2021.19","url":null,"abstract":"Introduction: Since the Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) first emerged in Wuhan, on 12 December 2019, it has spread rapidly across the world and developed into a pandemic. As healthcare workers are frequently in contact with Coronavirus disease-2019 (COVID-19) patients, they can be affected more often than the general population. In this study we aimed to investigate the SARS-CoV-2 seroprevalence and the IgG antibody levels among healthcare workers who frequently encountered COVID-19 patients in our hospital.Materials and Methods: In total, 182 healthcare workers were identified from database and their data was retrospectively analyzed. Participants with previous PCR positivity, pregnant, autoimmune disease history or immunosuppressive treatment history were excluded. Participants were grouped depending on their frequency of contact with COVID-19 patients (high and medium risk). All the samples were tested simultaneously for anti-SARS-CoV-2-IgG antibodies by the ELISA method. A chi-square test was used to compare categorical variables. A t-test and an ANOVA test were carried out to where appropriate.Results: Serological testing of 182 HCWs exposed to SARS-CoV-2 patients illustrated that 13.2% of them (24 out of 182) might have experienced an asymptomatic or subclinical SARS-CoV-2 infection. High risk participants, anosmia, and ageusia were statistically significant risk factors. The rate of detection of antibody positivity among doctors (p=0.030) and patients with anosmia, and ageusia (p=0.047) were found significantly higher than the others. In addition, SARS-CoV-2 antibody ratio results were found significantly higher in the groups of high risk participants (p=0.046), patients with clinical signs (p=0.008), myalgia (p=0.039), anosmia, and ageusia (p=0.025), respectively.Conclusion: Our study showed that serological testing is useful for determining asymptomatic or subclinical infections prevelance of SARS-CoV-2 among those with close contact with COVID-19 patients. Serological tests can be helpful determining the prevelance COVID-19 infection, especially among the HCWs.","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"40 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73554146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-09DOI: 10.4274/mjima.galenos.2022.2021.21
C. Sellitto, G. Scarpati, T. Ascione, G. Franci, O. Piazza, A. Filippelli, V. Conti, P. Pagliano
{"title":"Pharmacological Approaches to Visceral Leishmaniasis in Immunocompromised Patients","authors":"C. Sellitto, G. Scarpati, T. Ascione, G. Franci, O. Piazza, A. Filippelli, V. Conti, P. Pagliano","doi":"10.4274/mjima.galenos.2022.2021.21","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2022.2021.21","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"19 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81974270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-18DOI: 10.4274/mjima.galenos.2021.2021.11
Alper Tahmaz, Nefise Öztoprak, F. Kizilateş
{"title":"Investigation of Plasma Preseptin (sCD14-ST) Levels in Sepsis","authors":"Alper Tahmaz, Nefise Öztoprak, F. Kizilateş","doi":"10.4274/mjima.galenos.2021.2021.11","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.11","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"16 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78828121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-18DOI: 10.4274/mjima.galenos.2021.2021.8
N. Bataineh, Waleed Al Momani, Luai Abu-Ismail, Almu’atasim Khamees, I. Malkawi, Leen Al Momani, Muthanna Saraireh, M. Khatatbeh
{"title":"Stethoscope, Hand and Mobile Phone: Bacterial Contamination and Infection Control Among Medical and Nursing Students in Jordan","authors":"N. Bataineh, Waleed Al Momani, Luai Abu-Ismail, Almu’atasim Khamees, I. Malkawi, Leen Al Momani, Muthanna Saraireh, M. Khatatbeh","doi":"10.4274/mjima.galenos.2021.2021.8","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.8","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"74 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83763105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-18DOI: 10.4274/mjima.galenos.2021.2021.6
R. Saeidi, N. Izadi, Y. Mehrabi, K. Etemad, B. Eshrati, S. Hashemi-Nazari
{"title":"Factors Related to the Incidence of ICU-acquired Infections in Iran: Analysis of National Data","authors":"R. Saeidi, N. Izadi, Y. Mehrabi, K. Etemad, B. Eshrati, S. Hashemi-Nazari","doi":"10.4274/mjima.galenos.2021.2021.6","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.6","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"56 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74025312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-18DOI: 10.4274/mjima.galenos.2021.2021.9
S. Aydin, Okan Derin, M. Yılmaz
{"title":"A Case of an Endocarditis due to Coxiella burnetii","authors":"S. Aydin, Okan Derin, M. Yılmaz","doi":"10.4274/mjima.galenos.2021.2021.9","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.9","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"52 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89509170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-18DOI: 10.4274/mjima.galenos.2021.2021.10
S. Tehrani, Behnood Hatami, Sadaf Saket, Amirreza Keyvanfar
{"title":"Comparison of the Efficacy of Cefazolin with And without Naproxen in Patients with Cellulitis Admitted to a Tertiary Hospital; 2019-2020","authors":"S. Tehrani, Behnood Hatami, Sadaf Saket, Amirreza Keyvanfar","doi":"10.4274/mjima.galenos.2021.2021.10","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.10","url":null,"abstract":"","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"49 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77805234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-18DOI: 10.4274/mjima.galenos.2021.2021.16
Merve Kaplan, Aysegul Akkol Camurcu, S. Erol
Introduction: Some patients with Coronavirus disease-2019 (COVID-19) disease have persistent symptoms, and information about the long-term consequences of those who have recovered is limited. Thus, this study aimed to investigate the persistent symptoms of healthcare workers after COVID-19 and the relationship between demographic and clinical characteristics of patients. Materials and Methods: Healthcare workers who had symptomatic COVID-19 that is proven by reverse transcription-polymerase chain reaction and were diagnosed at least 12 weeks ago were included in the study. Demographic characteristics, comorbidities, and symptoms at the time of diagnosis and that persisted >3 weeks were examined in detail using a questionnaire. The effects of COVID-19 on the participants' quality of life were investigated using the EuroQoL five-dimension five-level (EQ-5D-5L) questionnaire and EuroQoL visual analog scale (EQ-VAS). Results: Of the 121 participants, the mean age was 33.5 years [22-59, standard deviation (SD)=8.23], and the mean time since their diagnoses with COVID-19 was 30.3 weeks (12.7-56.9, SD=12.6). Of the participants, 92% (n=112) were followed up as outpatients, 63% (n=77) had symptoms that lasting >3 weeks, and the most common symptoms were fatigue (n=40, 33%), loss of smell (n=27, 22.3%), and attention-deficit/concentration disorder (n=25, 20.7%). Of the 77 patients, 19 (24.6%) stated that their symptoms lasted for >24 weeks, with loss of smell as the most common symptom. Additionally, 33% of participants defined their health status as worse than before according to the EQ-5D-5L scale and 15% had a decrease of seven points or more in their EQ-VAS score. Conclusion: These results revealed that, even in young patients with mild and moderate COVID-19 infection, post-COVID-19 symptoms are at a rate that will affect their quality of life, thus health services should be planned for the rehabilitation of these patients.
{"title":"Post-COVID Syndrome in Healthcare Workers","authors":"Merve Kaplan, Aysegul Akkol Camurcu, S. Erol","doi":"10.4274/mjima.galenos.2021.2021.16","DOIUrl":"https://doi.org/10.4274/mjima.galenos.2021.2021.16","url":null,"abstract":"Introduction: Some patients with Coronavirus disease-2019 (COVID-19) disease have persistent symptoms, and information about the long-term consequences of those who have recovered is limited. Thus, this study aimed to investigate the persistent symptoms of healthcare workers after COVID-19 and the relationship between demographic and clinical characteristics of patients. Materials and Methods: Healthcare workers who had symptomatic COVID-19 that is proven by reverse transcription-polymerase chain reaction and were diagnosed at least 12 weeks ago were included in the study. Demographic characteristics, comorbidities, and symptoms at the time of diagnosis and that persisted >3 weeks were examined in detail using a questionnaire. The effects of COVID-19 on the participants' quality of life were investigated using the EuroQoL five-dimension five-level (EQ-5D-5L) questionnaire and EuroQoL visual analog scale (EQ-VAS). Results: Of the 121 participants, the mean age was 33.5 years [22-59, standard deviation (SD)=8.23], and the mean time since their diagnoses with COVID-19 was 30.3 weeks (12.7-56.9, SD=12.6). Of the participants, 92% (n=112) were followed up as outpatients, 63% (n=77) had symptoms that lasting >3 weeks, and the most common symptoms were fatigue (n=40, 33%), loss of smell (n=27, 22.3%), and attention-deficit/concentration disorder (n=25, 20.7%). Of the 77 patients, 19 (24.6%) stated that their symptoms lasted for >24 weeks, with loss of smell as the most common symptom. Additionally, 33% of participants defined their health status as worse than before according to the EQ-5D-5L scale and 15% had a decrease of seven points or more in their EQ-VAS score. Conclusion: These results revealed that, even in young patients with mild and moderate COVID-19 infection, post-COVID-19 symptoms are at a rate that will affect their quality of life, thus health services should be planned for the rehabilitation of these patients.","PeriodicalId":53879,"journal":{"name":"Mediterranean Journal of Infection Microbes and Antimicrobials","volume":"19 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89545574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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