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Role of Foam Sclerotherapy with Injection Ethanolamine Oleate for the Treatment of Venous Malformation in Head-Neck Region 注射用油酸乙醇胺泡沫硬化治疗头颈部静脉畸形
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2020-12-09 DOI: 10.3329/bjo.v26i2.50606
M. H. Rahman, Abirvab Naha, Riashat Azim Majumder, Khalid Mahmud, A. M. Jewel, K. Tarafder, A. Chowdhury, S. Rahman
Background: Venous malformations (VMs) are a variety of low flow vascular malformations, which are developmental error of morphogenesis of veins where veins are dysplastic lined by quiescent or normal endothelium. Although surgical extirpation is the standard method for the treatment of vascular malformations, this procedure often leads to significant loss of motor function, nerve damage, or massive bleeding in patients which may endanger the life. Therefore, sclerotherapy has now been accepted as a less invasive alternative and good results have been obtained. Objectives: This study was conducted to evaluate the clinical outcomes after Foam sclerotherapy with injection Ethanolamine Oleate (EO) for the treatment of VMs in head-neck region. Methods: This quasi-experimental study was conducted in the Department of Otolaryngology- Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU). Forty-three patients with venous malformation in head neck region that had the inclusion criteria were enrolled as a study sample. The patients were diagnosed mostly clinically & confirmed by demonstrating non-pulsatile blood flow and venous space using Duplex ultrasound. The sclerosing solution 5% Ethanolamine Oleate (EO) was used in this study. Sclerofoam was produced using the Tessari method in 4:1 air to liquid ratio, the foam had been used within 60- 90 seconds. Results of the study were categorized as excellent, good, fair and poor. Ethical clearance was obtained from the Institutional Review Board (IRB) of BSMMU. Results: Among 43 patients 34(79.1%) patients underwent single session and 9(20.9%) were two sessions. All the lesions were responded to EO. Response to sclerotherapy categorized as excellent were in two third 29 (67.4%) patients and 14 (32.6%) had good response. No sessions resulted in poor responses. No complications occurred following any procedures. All of the sessions were performed as a day case basis without anesthesia. Conclusions: Foam sclerotherapy with injection EO appears to be safe and effective for the treatment of VMs in the head and neck region and should be considered when treating these complex lesions. Bangladesh J Otorhinolaryngol; October 2020; 26(2): 79-85
背景:静脉畸形(Venous malformations, VMs)是一种低流量的血管畸形,是静脉形态发生的发育错误,静脉被静止或正常的内皮所包围。虽然手术切除是治疗血管畸形的标准方法,但手术往往会导致患者严重的运动功能丧失、神经损伤或大出血,危及生命。因此,硬化疗法已被认为是一种侵入性较小的替代方法,并取得了良好的效果。目的:评价油酸乙醇胺(EO)泡沫硬化治疗头颈部vm的临床效果。方法:本准实验研究在Bangabandhu Sheikh Mujib医科大学耳鼻咽喉头颈外科进行。纳入43例符合纳入标准的头颈部静脉畸形患者作为研究样本。患者多为临床诊断,通过双工超声显示无搏动性血流及静脉间隙来确诊。本研究采用5%乙醇胺油酸酯(EO)作为硬化液。采用Tessari法在4:1的气液比下制备硬泡沫,泡沫在60- 90秒内用完。研究结果分为优秀、良好、一般和差。获得了BSMMU机构审查委员会(IRB)的伦理许可。结果:43例患者中34例(79.1%)为单次治疗,9例(20.9%)为两次治疗。所有病变均对EO有反应。2 / 3的患者(67.4%)对硬化治疗反应良好,14(32.6%)对硬化治疗反应良好。没有会议导致不良反应。手术后无并发症发生。所有的疗程都是在没有麻醉的情况下进行的。结论:泡沫硬化联合注射EO治疗头颈部vm安全有效,在治疗此类复杂病变时应予以考虑。孟加拉国J耳鼻咽喉;2020年10月;26 (2): 79 - 85
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引用次数: 0
Prevention of Deafness in Bangladesh 孟加拉国的耳聋预防
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2020-12-09 DOI: 10.3329/bjo.v26i2.50605
A. H. Joarder, Nazmul Islam
Abstract Not Available Bangladesh J Otorhinolaryngol; October 2020; 26(2): 77-78
摘要不可用孟加拉国耳鼻喉科杂志;2020年10月;26(2):77-78
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引用次数: 0
Evaluation of Hypoparathyroidism following Total Thyroidectomy 甲状腺全切除术后甲状旁腺功能减退的评价
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2020-12-09 DOI: 10.3329/bjo.v26i2.50612
Md Nazmul Haque, S. Khan, Moshammat Fatima Akhter, M. A. Bhuiyan, Mohammad Zakaria Sarker, M. A. Sakik
The most common cause of hypoparathyroidism is damage to the glands during thyroid surgery. Parathyroid gland preservation during thyroidectomy is not only desirable, but essential for the effective management of surgical diseases of the thyroid gland Objective: To find out the incidence rate of hypoparathyroidism after total thyroidectomy. Methods: Study Period: 2 years from Jan 2017 to December 2018 Place of Study : National Institute of ENT, Tejgaon, Dhaka Study Design: Prospective Observational Study Sample size: 107 Sampling Technique: Convenient Sampling technique Results: Among the 107 cases 39 cases were malignant comprising 36.45% of the cases. toxic multinodular goitre were 6 cases among 107 cases (5.6%) and rest 62 cases were benign multinodular goitre with or without cystic change and follicular adenomas (57.94 %). 29 cases out of 39 malignant cases were papillary carcinoma of thyroid (74.36% of malignant lesions), 2 cases of medullary Ca thyroid (5.12 % of malignant lesions) rest 8 were follicular carcinoma (20.51% of malignant lesions). 26 out of 107 (24.30%) cases suffered from postoperative hypocalcaemic tetany within 1st-5th POD. Their parathyroid hormones were significantly reduced and serum calcium were also reduced and they required calcium supplementation. In 5 (4.67%) cases there was no sign and symptoms of tetany but their serum parathormone levels were little below normal level but serum calcium levels were normal and therefore no calcium supplementation were given. The rest 76 (71.03%) cases did not show any sign or symptoms of tetany and did not require calcium supplementation. Among the patients who suffered from tetany majority were cases of Carcinoma of thyroid (18 out of 26 patients of hypoparathyroidism) 69.23%, however lateral neck dissection did not seem to affect decline in parathyroid function as 10 out of 18 patients with thyroid malignancy who suffered from postoperative tetany undergone level II to level V neck dissection in addition to total thyroidectomy. Bangladesh J Otorhinolaryngol; October 2020; 26(2): 116-120
甲状旁腺功能减退症最常见的原因是甲状腺手术中的腺体损伤。甲状腺切除术中保留甲状旁腺不仅是可取的,而且对于有效治疗甲状腺外科疾病至关重要。目的:了解甲状腺全切除术后甲状旁腺功能减退的发病率。方法:研究时间:2年,自2017年1月至2018年12月研究地点:达卡特冈国家耳鼻喉科研究所研究设计:前瞻性观察研究样本量:107抽样技术:方便抽样技术结果:107例病例中39例为恶性,占36.45%。毒性多结节性甲状腺肿107例中有6例(5.6%),其余62例为良性多结节甲状腺肿伴或不伴囊性改变和滤泡腺瘤(57.94%)。39例恶性病例中29例为甲状腺乳头状癌(占恶性病变的74.36%),2例为甲状腺髓质钙癌(占肿瘤病变的5.12%),其余8例为滤泡癌(占病变的20.51%)。107例患者中有26例(24.30%)在术后第1~5个POD内出现低钙血症性破伤风。他们的甲状旁腺激素显著降低,血清钙也降低,需要补充钙。在5例(4.67%)病例中,没有破伤风的体征和症状,但他们的血清甲状旁腺激素水平略低于正常水平,但血清钙水平正常,因此没有补充钙。其余76例(71.03%)未出现任何手足口炎的体征或症状,也不需要补钙。在患有破伤风的患者中,大多数是甲状腺癌(26例甲状旁腺功能减退患者中有18例)69.23%,但侧颈清扫似乎不会影响甲状旁腺功能的下降,因为18例甲状腺恶性肿瘤患者中有10例患有术后破伤风,除全甲状腺切除术外,还接受了II至V级颈清扫。孟加拉国耳鼻喉科杂志;2020年10月;26(2):116-120
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引用次数: 0
A Comparative Study of Coblation versus Dissection Tonsillectomy 消融扁桃体切除术与夹层扁桃体切除术的比较研究
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2020-12-09 DOI: 10.3329/bjo.v26i2.50613
Dipankar Lodh, SM Abdul Awual, Tawhidul Islam Mondol, S. Islam, Mohammad Nazrul Islam, H. Rashid
Objectives: To compare the efficacy of coblation tonsillectomy and dissection tonsillectomy regarding the duration of surgery, amount of intraoperative bleeding, postoperative pain, recovery time and complications. Methods: 50 patients aged 5-30 years with chronic tonsillitis who underwent tonsillectomy operation were randomly divided into two groups. One group underwent coblation tonsillectomy while other group with dissection tonsillectomy. Chronic tonsillitis patients with adenoid hypertrophy and Otitis media with effusion were excluded by diagnostic nasal endoscopy, imaging and audiometry. All patient were examined regularly after surgery for 10 days to assess the postoperative morbidity and efficacy of both coblation and dissection methods. Duration of surgery, amount of intraoperative bleeding, recovery time, postoperative pain& requirement of analgesics, time required to regain normal diet & activityand complication were assessed. Result: Comparing the coblation tonsillectomy to cold dissection group the mean duration of surgery was 9.7 versus 18.4 minutes, the amount of intra operative bleeding 10.62 versus 28.72 milliliter. The difference on the postoperative pain scale, requirement of analgesics, condition of the tonsillar fossa, time required to regain normal diet & activity between two groups were statistically significant. Conclusion: In our study patient underwent coblation tonsillectomy providing a near bloodless field, minimum operating time, less postoperative pain, quicker return to normal diet, normal activity and less use of analgesics than patients underwent dissection tonsillectomy. Postoperative morbidity and complications were lower as compared to conventional cold dissection technique. Bangladesh J Otorhinolaryngol; October 2020; 26(2): 121-127
目的:比较消融扁桃体切除术与夹层扁桃体切除术在手术时间、术中出血量、术后疼痛、恢复时间及并发症等方面的疗效。方法:50例5 ~ 30岁行扁桃体切除术的慢性扁桃体炎患者随机分为两组。一组行消融扁桃体切除术,另一组行夹层扁桃体切除术。慢性扁桃体炎伴腺样体肥大及中耳炎伴积液者经诊断性鼻内窥镜、影像学及听力学检查排除。所有患者术后10天定期检查,以评估消融和剥离方法的术后发病率和疗效。评估手术时间、术中出血量、恢复时间、术后疼痛及镇痛药需求、恢复正常饮食及活动所需时间及并发症。结果:消融扁桃体切除术组与冷剥离组比较,平均手术时间9.7 min vs . 18.4 min,术中出血量10.62 ml vs . 28.72 ml。两组患者术后疼痛程度、镇痛药需求、扁桃体窝状况、恢复正常饮食活动所需时间差异均有统计学意义。结论:在我们的研究中,与分离扁桃体切除术患者相比,消融扁桃体切除术患者提供了一个接近无血的区域,手术时间最短,术后疼痛更少,更快恢复正常饮食,正常活动和更少使用止痛药。与传统冷解剖技术相比,术后发病率和并发症均较低。孟加拉国J耳鼻咽喉;2020年10月;26 (2): 121 - 127
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引用次数: 3
Evaluation of Hearing Status in Pre and Postoperative Canal Wall Down Mastoidectomy with Type III Tympanoplasty with or without Cartilage Augmentation III型鼓室成形术伴或不伴软骨增强的乳突管下壁切除术前后听力状况的评价
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2020-12-09 DOI: 10.3329/bjo.v26i2.50607
M. Hanif, Zahedul Alam, K. Tarafder, Rojibul Haque, Mohammad Shaharior Arafat, M. M. Rahman
Objective: To evaluate Hearing Status in Pre and Post-operative Canal Wall Down Mastoidectomy with Type III Tympanoplasty with or without cartilage augmentation. Methods: This was a prospective study, done in Otolaryngology & Head Neck Surgery department of Sir Salimullah Medical College Mitford Hospital(SSMCMH) and Bangabandhu Sheikh Mujib Medical University(BSMMU) , Dhaka, Bangladesh. 1stJuly to 31st December, 2012. Forty patients were studied in this series. Results: The results concluded that mean pre and post-operative air bone gap were 38.5 dB and 29.69 dB respectively with a net gain of 8.81 dB in Canal wall down mastoidectomy with cartilage augmented Tympanoplasty type III which is statistically significant. The postoperative PTA-ABG ranged from 25-36 dB , the ABG closure was 11-15 dB in 40% case. Whereas mean pre and post-operative air bone gap were 37.19 dB and 34.19 dB respectively with a net gain of 3 dB in Canal wall down mastoidectomy without cartilage augmented Tympanoplasty type III which is statistically insignificant. The post-operative PTA-ABG ranged from 26.25-41.75 dB, the ABG closure was 0-5 dB in 35% case. Conclusion: Hearing results after cartilage augmentation in type iii Tympanoplasty showed improvement at individual and mean post-operative PTA-ABG and also improvement in ABG closure suggesting thin cartilage disc increased the effective vibrating area of tympanic membrane graft. Bangladesh J Otorhinolaryngol; October 2020; 26(2): 86-94
目的:评价带或不带软骨增强的III型鼓室成形术前后管壁下乳突切除术的听力状况。方法:这是一项前瞻性研究,在孟加拉国达卡的Salimullah爵士医学院Mitford医院(SSMCMH)和Bangabandhu Sheikh Mujib医科大学(BSMMU)的耳鼻咽喉和头颈外科进行。2012年7月1日至12月31日。本系列共研究了40名患者。结果:结果表明,在III型软骨增强鼓室成形术的管壁下乳突切除术中,术前和术后平均气骨间隙分别为38.5dB和29.69dB,净增益为8.81dB,具有统计学意义。术后PTA-ABG范围为25-36dB,40%的病例ABG闭合范围为11-15dB。而在没有软骨增强型III型鼓室成形术的管壁下乳突切除术中,术前和术后平均气骨间隙分别为37.19dB和34.19dB,净增益为3dB,这在统计学上是不显著的。术后PTA-ABG范围为26.25-41.75dB,35%的病例ABG闭合为0-5dB。结论:iii型鼓室成形术中软骨增强后的听力结果显示,个体和平均术后PTA-ABG均有改善,ABG闭合也有改善,这表明薄软骨盘增加了鼓膜移植物的有效振动面积。孟加拉国耳鼻喉科杂志;2020年10月;26(2):86-94
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引用次数: 0
Comparison of Surgical Outcome between Endoscopic and Microscopic Type 1 Tympanoplasty 内镜和显微镜下1型鼓室成形术的疗效比较
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2020-12-09 DOI: 10.3329/bjo.v26i2.50611
Khalid Mahmud, M. Alam, Mainul Islam, M. H. Rahman, Riashat Azim Majumder, N. Akhtar, P. G. Datta, Abirvab Naha
Background: Chronic otitis media (COM) is the long-standing infection of a part or whole of middle ear cleft characterized by ear discharge & perforation. The most common presenting symptoms are ear discharge, mild to severe hearing loss, sometimes tinnitus even vertigo. Treatment of COM is mainly operative. The treatment of inactive mucosal variety of COM is Type 1 tympanoplasty. It can be done by microscopic or endoscopic technique. Both methods have some merits and demerits. Objectives: Aim of the study was to compare the surgical outcomes between endoscopic and microscopic type 1 tympanoplasty. Methods: This study was carried out in the Department of Otolaryngology–Head & Neck surgery of Bangabandhu Sheikh Mujib Medical University, Dhaka from March 2017 to June 2019 and 60 (30 in each group) patient were included in the study. All patients underwent type 1 tympanoplasty. In Group A endoscopic tympanoplasty cases and in Group B microscopic tympanoplasty cases were placed. Operation duration, post-operative pain, postoperative hearing status, graft uptake was compared in two groups. Results: There were no significant difference of graft uptake and hearing gain (>0.05). But endoscopic operative time and post-operative pain were less than microscopic group (<0.05). Conclusion: Through endoscopic tympanoplasty is a newer approach and it has some limitations. As endoscopic tympanoplasty requires less time, less pain with similar graft uptake and audiological success. It can be adopted as an alternative method of tympanoplasty. Bangladesh J Otorhinolaryngol; October 2020; 26(2): 109-115
背景:慢性中耳炎(Chronic otitis medium, COM)是中耳裂口部分或全部的长期感染,表现为耳漏及耳穿孔。最常见的症状是耳塞,轻微到严重的听力损失,有时耳鸣甚至眩晕。COM的治疗以手术为主。1型鼓室成形术治疗COM的无活性粘膜病变。它可以通过显微镜或内窥镜技术来完成。两种方法各有优缺点。目的:比较内镜下与显微镜下1型鼓室成形术的手术效果。方法:本研究于2017年3月至2019年6月在达卡Bangabandhu Sheikh Mujib医科大学耳鼻喉头颈外科进行,共纳入60例患者(每组30例)。所有患者均行1型鼓室成形术。A组为内窥镜鼓室成形术组,B组为镜下鼓室成形术组。比较两组患者手术时间、术后疼痛、术后听力、移植物摄取情况。结果:两组患者移植物摄取和听力增加无显著差异(>.05)。但内镜组手术时间和术后疼痛均少于镜下组(<0.05)。结论:内镜下鼓室成形术是一种较新的方法,但存在一定的局限性。由于内窥镜鼓室成形术需要更少的时间,更少的疼痛,具有相似的移植物摄取和听力学成功。它可以作为鼓室成形术的一种替代方法。孟加拉国J耳鼻咽喉;2020年10月;26 (2): 109 - 115
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引用次数: 1
Patterns of Neck Node Metastasis in Carcinoma of Oral Cavity 口腔癌颈淋巴结转移的类型
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2020-12-09 DOI: 10.3329/bjo.v26i2.50610
S. Ahmed, A. Delwar, J. A. Mazumder, M. Rashid, M. M. Khan, M. Mahamud, Mostafizur Rahman
Objectives: To find out the patterns of cervical lymph node metastasis in oral cavity carcinoma. Methods: This is across sectional study which was carried out in the department of Otolaryngology & Head Neck Surgery Dhaka Medical College Hospital (DMCH), Sir Salimullah Medical College Hospital (SSMC), Bangabandhu Sheikh Mujib Medical University (BSMMU) and National Institute of Cancer Research & Hospital (NICRH) from July 2013 to December 2014.Total 96 cases were included in this study. Data were collected by detail history, clinical examination, relevant investigation and result were processed manually and analyzed with the help of SPSS. Results: In this study 72 (75%) patients presented with clinically palpable neck nodes and 24 (25%) presented without neck node. Among 24 cases 7 cases was radiologically positive neck node. Out of 96 cases stage III was the highest (50.96%) followed by stage IV (27.01%), stage II (13.52%) and stage I (8.32%). That is 23 (23.92%) patients present with early stage and 73 (76.18%) patients present in late or advanced stage. Level l was the highest 49 (61.71%), followed by level all 35(44.1%), level lll 10 (12.6%). Conclusion: As cervical lymph node metastasis is a critical event for patients with squamous cell carcinoma of oral cavity, as this is the most reliable predictor of poor treatment outcomes. Thus for appropriate treatment it is very important to know this pattern of metastases. Bangladesh J Otorhinolaryngol; October 2020; 26(2): 102-108
目的:了解口腔癌颈淋巴结转移的规律。方法:本研究于2013年7月至2014年12月在达卡医学院医院(DMCH)、萨利穆拉爵士医院(SSMC)、班加班杜·谢赫·穆吉布医科大学(BSMMU)和国家癌症研究与医院研究所(NICRH)耳鼻咽喉和头颈外科进行。共96例病例纳入本研究。通过详细病史、临床检查、相关调查收集数据,人工处理结果,并借助SPSS进行分析。结果:在这项研究中,72名(75%)患者出现临床可触及的颈部淋巴结,24名(25%)患者没有出现颈部淋巴结。在24例病例中,7例颈部淋巴结放射学阳性。在96例病例中,III期最高(50.96%),其次是IV期(27.01%)、II期(13.52%)和I期(8.32%)。即23例(23.92%)早期患者和73例(76.18%)晚期或晚期患者。l级最高49例(61.71%),其次为all 35例(44.1%),lll 10例(12.6%)。因此,对于适当的治疗来说,了解这种转移模式是非常重要的。孟加拉国耳鼻喉科杂志;2020年10月;26(2):102-108
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引用次数: 0
Bilateral Langerhans Cells Histiocytosis in the Temporal Bone: A case report 双侧颞骨郎格汉斯细胞组织细胞增多症1例
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2020-07-01 DOI: 10.3329/bjo.v26i1.47956
K. L. Saha, B. P. Dey, A. H. Joarder, M. A. Haque, B. Bhowmik
Langerhans cells histiocytosis (LCH) or histiocytosis-X is a rare group diseases that includes three overlapping diseases of Hand-Schuller-Christian disease (HSC), Letterer-Siwe disease (LS)and Eosinophilic granuloma(EG). It results from clonal proliferation of histiocytes having similar morphology and immunophenotype to Langerhans cells in skin and mucosa Though head and neck manifestation is common, isolated simultaneous bilateral temporal bone Langerhans Cell Histiocytosis is an extremely rare presentation. Having same otological menifestations, high resolution CT scan is advocated for early identification and differentiation of LCH from other common conditions such as mastoidits,otitis externa ,chronic suppurative otitis media. Diagnosis of LCH is confirmed by biopsy and immunohistochemical staining of S-100 protein and or CD1a antigen. Chemotherapy is main mode of treatment.The prognosis is worse when presenting age of children is younger than 2 years. 1. Associate Professor, Department of Otolaryngology and Head-Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. 2. Professor, Department of Otolaryngology and Head-Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 3. Assistant Registrar, Department of ENT, Shaheed Tajuddin Ahmed Medical College, Gazipur,Bangladesh. 4. Associate Professor, Department of Radiology and Imaging, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 5. Assistant Professor, Department of Pathology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh Address of Correspondence: Dr. Kanu Lal Saha, Associate Professor, Otology Division, Department of Otolaryngology and Head-Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, Room no.702,BlockC,BSMMU, Email:drklsaha@gmail.com Introduction: Langrhans cells histiocytosis (LCH) or histiocytosis-X is a rare group diseases that includes Hand-Schuller-Christian disease (HSC), Letterer-Siwe disease(LS) and Eosinophilic granuloma(EG). It results from clonal proliferation of histiocytes which has similarity in morphology and immunophenotype to Langerhans cells located in the skin and mucosa. The Writing Group of the Histiocyte Society recommendedthe term LCH in 1987. The incidence of LCH is 5.4 per million. It may present any age but average onset of age is between 1-3 years with a male predominance. Though it may involve any organ head and neck is affected in about 55-73% cases. Temporal bone involvement in LCH is variable ranging from 4-61%. Bilateral
Langerhans细胞组织细胞增多症(LCH)是一种罕见的群体性疾病,包括Hand-Schuller-Christian病(HSC)、Letter-Siwe病(LS)和嗜酸性肉芽肿(EG)三种重叠疾病。它是由皮肤和粘膜中与郎格汉斯细胞具有相似形态和免疫表型的组织细胞的克隆增殖引起的。尽管头颈部表现很常见,但孤立的双侧颞骨郎格汉斯组织细胞增多症是一种极为罕见的表现。由于具有相同的耳科特征,高分辨率CT扫描被提倡用于早期识别和区分LCH与其他常见疾病,如乳突、外耳道炎、慢性化脓性中耳炎。LCH的诊断通过活检和S-100蛋白和/或CD1a抗原的免疫组织化学染色来证实。化疗是主要的治疗方式。当儿童年龄小于2岁时,预后更差。1.孟加拉国达卡Bangabandhu Sheikh Mujib医科大学耳鼻咽喉和头颈外科副教授。2.孟加拉国达卡Bangabandhu Sheikh Mujib医科大学耳鼻咽喉和头颈外科教授3。孟加拉国加齐普尔Shaheed Tajuddin Ahmed医学院耳鼻喉科助理注册主任。4.孟加拉国达卡Bangabandhu Sheikh Mujib医科大学放射和成像系副教授5。孟加拉国达卡Bangabandhu Sheikh Mujib医科大学病理学系助理教授通讯地址:Kanu Lal Saha博士,孟加拉达卡Bangaband hu SheikhMujib医学大学耳鼻咽喉和头颈外科耳鼻科副教授,BSMMU C区702室,电子邮箱:drklsaha@gmail.com引言:郎汉斯细胞组织细胞增多症(LCH)或组织细胞增多病-X是一种罕见的群体性疾病,包括Hand-Schuller-Christian病(HSC)、Letter-Siwe病(LS)和嗜酸性肉芽肿(EG)。它是由组织细胞的克隆增殖引起的,组织细胞在形态和免疫表型上与皮肤和粘膜中的郎格汉斯细胞相似。组织细胞学会写作小组于1987年推荐了LCH一词。LCH的发病率为百万分之5.4。它可以表现为任何年龄,但平均发病年龄在1-3岁之间,以男性为主。尽管它可能涉及任何器官,但大约55-73%的病例中头部和颈部受到影响。LCH的颞骨受累率在4-61%之间。双方的
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引用次数: 2
Utility of Tolonium Chloride Rinse in the Diagnosis of Oral Cancer 氯铵冲洗液在口腔癌症诊断中的应用
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2020-07-01 DOI: 10.3329/bjo.v26i1.47947
Kamruzzaman, Kazi Nurjahan, A. Sharifuddin, SK Ballav
Background: Oral cancer burden in developing countries is huge. In Bangladesh and India incidence were 10.6% and 10.4% respectively on 2018. At the same time worldwide incident was only 2%. Majority patients present at advanced stage and their survival rate is poor. Diagnostic delay from patient side and health delivery system side is significantly longer and it is more in developing countries. Like other malignancy early diagnosis can save a lot of these patient. Methods: This prospective study was carried out in Khulna Medical College Hospital from July 2017 to July 2019. Patients who will meet the criteria for this prospective study and capable and willing to give informed consent were enrolled. 20 second rinse/gargle with 10ml of 1% Tolonium chloride solution was done. Biopsy were taken from stained lesion, biopsy report were compared with TC stained lesions. Results: Out of 1650 patients in our outdoor department for various problem and only 30 cases were selected for this study according to selection criteria. Of 30 patients, 18 (60%) were male and 12 (40%) were female. The male-to-female ratio was 3:2. It was found that the sensitivity of 1% Tolonium Chloride rinse for oral precancer and cancer detection was 83.33%, whereas the specificity was 84.21%. Conclusion: Tolonium chloride rinse is a good screening test for oral cancer diagnosis with sensitivity 83.33% and specificity 84.21%.
背景:发展中国家口腔癌症负担巨大。2018年,孟加拉国和印度的发病率分别为10.6%和10.4%。与此同时,全球范围内的事故仅占2%。大多数患者处于晚期,生存率很低。患者和医疗服务系统方面的诊断延迟要长得多,发展中国家的诊断延迟更多。像其他恶性肿瘤一样,早期诊断可以挽救很多这样的病人。方法:本前瞻性研究于2017年7月至2019年7月在库尔纳医学院医院进行。符合本前瞻性研究标准且有能力且愿意给予知情同意的患者被纳入研究。用10ml 1%的Tolonium氯化物溶液冲洗/漱口20秒。对染色病变进行活检,并将活检报告与TC染色病变进行比较。结果:在我们室外科的1650名因各种问题的患者中,根据选择标准,只有30例被选入本研究。在30名患者中,18名(60%)为男性,12名(40%)为女性。男女比例为3:2。结果表明,1%氯氯铵冲洗液对口腔癌前病变和癌症的敏感性为83.33%,特异性为84.21%。
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引用次数: 0
Comparative Study of Neck Swelling by Clinical, Cytological and Histopathological Examination 颈部肿胀的临床、细胞学和组织病理学比较研究
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2020-07-01 DOI: 10.3329/bjo.v26i1.47949
Mohammad Ali, M. Huq, M. Haque, K. Tarafder
Objective: In this study 50 patients of neck swelling were studied to compare the findings with clinical diagnosis and histopathological report for its diagnostic compatibility. Methods: This cross sectional study was done in Department of Otolaryngology –Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2015 to June 2017. Fine needle aspiration cytology, MRI, CT scan, and histopathological examination of postoperative specimen of neck swelling, analyzed data presented by various tables, graphs and figures. Results:In the present series 50 cases of neck swelling were studied. Out of these 50 cases 19 were male and 31 were female. The male, female ratio was 1:1.63. Age range was 4 – 60 years with maximum frequency in the 4 decade with the 3 and 2 in the following suit. Most of the patient were poor. Clinical, cytological and histopathological diagnosis were available in all the cases. The three sorts of diagnoses were compared with each other. Histopathologically 12 cases were tubercular lymphadenopathy. Metastatic carcinoma and lymphoma 5 cases for each. Twelve were nodular goiter, 5 were thyroid carcinoma. Rest were benign, congenital and nonspecific inflammatory conditions. Correct diagnosis were made by FNAC in 45 cases. In the rest 5 cases smear were unsatisfactory in 2 cases and gives inconclusive result, remaining 3 were follicular neoplasm and no definitive result were made which were subsequently diagnosed by histopathological examination as a follicular adenoma in 1 and follicular carcinoma in 2. Sensitivity of FNAC in the diagnosis of neck masses were found 91% for tuberculosis, 100% for metastatic carcinoma also for salivary gland tumour. In case of nodular goiter sensitivity was 92%. But it is only 60% sensitive in case of thyroid malignancy, as FNAC can not demarcate clearly between follicular adenoma and follicular cell carcinoma. But its accuracy in diagnosing papillary cell carcinoma of thyroid was 100%. Conclusion: Keeping the limitations in mind, FNAC can reduce substantially the need of open biopsy for histopathological examination. Last of all I wish to conclude the study with the popular saying of Stewart “Diagnosis by aspiration is as reliable as the combined intelligence of the clinician and pathologist makes it”.
目的:对50例颈部肿胀患者进行研究,比较其表现与临床诊断及组织病理学报告的诊断相容性。方法:本横断面研究于2015年7月至2017年6月在达卡班班杜谢赫穆吉布医科大学耳鼻咽喉头颈外科完成。对术后颈部肿胀标本进行细针抽吸细胞学、MRI、CT扫描、组织病理学检查,并以各种表格、图表、图形的形式对数据进行分析。结果:本文对50例颈部肿胀进行了研究。在这50例病例中,男19例,女31例。男女比例为1:1.63。年龄范围为4 ~ 60岁,以40年最多,3、2年次之。大多数病人都很穷。所有病例均有临床、细胞学和组织病理学诊断。对三种诊断方法进行比较。组织病理学检查为结核性淋巴结病12例。转移性癌、淋巴瘤各5例。结节性甲状腺肿12例,甲状腺癌5例。其余为良性、先天性和非特异性炎症。FNAC正确诊断45例。其余5例中,2例涂片不满意,结果不明确,3例为滤泡性肿瘤,无明确结果,经组织病理学检查,1例诊断为滤泡性腺瘤,2例诊断为滤泡性癌。FNAC诊断颈部肿块对结核的敏感性为91%,对转移癌和唾液腺肿瘤的敏感性为100%。结节性甲状腺肿的敏感性为92%。但由于FNAC不能明确区分滤泡腺瘤和滤泡细胞癌,因此对甲状腺恶性肿瘤的敏感性仅为60%。但对甲状腺乳头状细胞癌的诊断准确率为100%。结论:考虑到局限性,FNAC可以大大减少对组织病理学检查的开放活检的需要。最后,我想用斯图尔特的一句名言来结束我的研究:“临床医生和病理学家的共同智慧使期望诊断同样可靠”。
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引用次数: 2
期刊
Bangladesh Journal of Otorhinolaryngology
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