Operative Neurosurgery最新文献

Background and objectives: Cerebral bypass can provide flow augmentation for select patients with moyamoya disease (MMD) and steno-occlusive cerebrovascular disease (SOCD). Earlier work has suggested that sacrificing the nondonor branch of the superficial temporal artery (STA) can optimize direct flow, which we assessed in real time.

Methods: This was a single-institution observational study of consecutive patients undergoing direct STA-middle cerebral artery (MCA) bypass with indirect encephalo-duro-myo-synangiosis for MMD and SOCD over 1 year. Excluding patients with significant STA-intracranial collateralization, the intraoperative effect of nondonor STA branch temporary occlusion on direct STA-MCA bypass flow was assessed using a Charbel flow probe. Patient characteristics and perioperative and postoperative data were reviewed.

Results: Eleven patients (5 MMD, 6 SOCD; mean age 53.5 ± 15.3 years) underwent combined revascularization (4 left, 7 right). The mean donor STA branch flow increased from 4.91 ± 2.79 (baseline) to 16.63 ± 11.92 mL/min after anastomosis (95% CI 1.25-17.50; P = .015), and to 20.94 ± 10.63 mL/min after nondonor STA branch test occlusion (95% CI 1.71-6.90; P = .002). The parietal STA branch was used as the donor in 8 cases (72%). In 9 patients, the nondonor STA branch was sacrificed. Perioperatively, 1 patient experienced transient dysarthria/paresthesias (9.1%); there were no strokes or other major complications. The median hospital stay was 5.0 (IQR 4.0, 7.0) days, with 81% of patients discharged home. Over a mean follow-up of 6.2 ± 3.0 months, no patients had significant wound-healing issues, and the median modified Rankin Scale score improved from 2 (IQR 1.0, 2.5) preoperatively to 0 (IQR 0.0, 0.0) (95% CI 0.11-1.69; P < .015). Six-month angiography (available in 9 patients) demonstrated 100% direct bypass patency and a median direct bypass flow grade of 2.0 (IQR 2.0, 3.0).

Conclusion: In patients without STA-intracranial anastomoses, STA-MCA direct bypass flow may be optimized safely by nondonor STA branch sacrifice.

Background and objectives: Transforaminal lumbar interbody fusion (TLIF) allows for direct and indirect decompression and segmental lordosis in sagittal plane correction. This study compares the effectiveness of "Bullet" type and "Banana" type devices for sagittal plane correction.

Methods: Patients who underwent 1-level or 2-level TLIF for degenerative pathology at a single tertiary care center were identified. Details were extracted on demographics, interbody dimensions, and preoperative and postoperative lumbopelvic parameters from upright radiographs. Cages were categorized as "Bullet" or "Banana" type based on morphology and manufacturer description of optimal position. Univariable comparisons between levels treated with "Bullet" and "Banana" type interbodies were performed. Multivariable linear regression was performed to identify independent predictors of postoperative segmental lordosis and change in segmental lordosis.

Results: One hundred and ninety eight unique patients (median 66.6 years; [IQR 59.5, 73.7]; 56.6% female) were included with 241 levels treated, of which 114 (52.7%) were treated with "Banana" type interbodies and 127 (47.3%) with "Bullet" type. "Banana" type interbodies afforded both greater postoperative segmental lordosis (8.1 [6.2, 10.7] vs 7.5 [5.2, 9.6]; P = .048) and greater increase in segmental lordosis (3.3 [0.7, 7.0] vs 2.3 [0.1, 4.2]; P = .015). On multivariable linear regression, only preoperative segmental lordosis (β = 0.322 per degree; [0.244, 0.399]; P < .001), implant listed lordosis (β = 0.146 per degree; 95% CI [0.048, 0.244]; P = .004), preoperative pelvic incidence (0.072 per degree; [0.034, 0.111]; P < .001), and use of bilateral TLIF windows (β = 3.133; [1.213, 5.053]; P = .001) were predictive of postoperative segmental lordosis.

Conclusion: The present analysis suggests that baseline lumbopelvic anatomy, interbody lordosis, and the use of bilateral TLIF windows are the most important predictors of postoperative segmental lordosis. Use of "Banana" vs "Bullet" type interbodies was not predictive of segmental lordosis achieved on immediate postoperative upright radiographs. Further work is merited to determine whether the 2 interbody types demonstrate differences regarding subsidence risk or maintenance of correction.

Background and objectives: The training of cerebrovascular neurosurgeons faces significant challenges, particularly due to the decreasing volume of aneurysm clipping procedures. Traditional training methods rely heavily on clinical case availability, which limits skill development. This study aimed to implement and validate a Microsurgical Aneurysm Training Simulator (MATS) that offers a comprehensive, realistic, and cost-effective solution for neurosurgical training.

Methods: MATS was designed using semiautomated algorithms and additive manufacturing to replicate a bifurcation aneurysm of the middle cerebral artery. The simulator includes a pulsatile perfusion system and is compatible with indocyanine-green angiography. The simulation was evaluated by medical students, residents, and experienced neurosurgeons through face, content, and construct validity assessments. Performance was measured using a modified Objective Structured Assessment of Aneurysm Clipping Skills.

Results: MATS demonstrated high face and content validity, particularly in replicating the visual and procedural aspects of aneurysm clipping. Participants across all experience levels showed significant improvements in modified Objective Structured Assessment of Aneurysm Clipping Skills scores, with medical students displaying the most pronounced learning curve. The simulators compatibility with indocyanine green angiography was confirmed, though limitations were noted in replicating physiological perfusion pressures and the visual impact of subarachnoid hemorrhage during aneurysm rupture simulations.

Conclusion: MATS is a validated, cost-effective, and reproducible tool that significantly enhances neurosurgical training by improving technical skills, especially in inexperienced participants. While the simulator effectively mimics key aspects of aneurysm surgery, further research is needed to assess its predictive validity and its potential impact on actual surgical outcomes.

Background and objectives: After surgical drainage of a chronic subdural hematoma (cSDH), middle meningeal artery (MMA) embolization aids in preventing the revascularization of the cSDH membranes at the capillary level and, in turn, reaccumulation. With the MMA circulation ipsilateral to the surgical side often being disrupted, there is recruitment of collaterals from the contralateral MMA tree to the ipsilateral cSDH membranes. The aim of this study was to demonstrate the ability of additive contralateral liquid embolic (LE) injection after ipsilateral surgery to augment MMA embolization. We hypothesized that contralateral LE injection may provide additional MMA embolization to the affected ipsilateral side and increase response to treatment.

Methods: Consecutive cases of unilateral cSDH surgery with ipsilateral MMA embolization and additive contralateral LE injection were retrospectively identified from a prospectively maintained database of the senior authors.

Results: Over the study period, 26 consecutive cases of recurrent cSDH after unilateral surgery were identified. There was an average age of 73 ± 2.7 years (range 27-90 years), and 14 patients (54%) were female. All 26 patients (100%) had previous burr holes or a craniotomy. The average cSDH thickness after surgery and before embolization was 10 ± 0.3 mm, and the average midline shift was 3.5 ± 0.7 mm. Of the 26 patients who underwent bilateral MMA embolization, 96% had over-the-top contralateral-to-ipsilateral LE injection and penetration, providing additional embolization to membranes of the index ipsilateral cSDH. The average cSDH thickness on follow-up was 4 ± 5 mm and midline shift of 0.2 ± 0.7 mm. Complete cSDH resolution was achieved in 7 patients (39%). Two patients had cSDH recurrence, one of which required reoperation. There were no LE or catheter-related complications.

Conclusion: Contralateral MMA embolization in patients who have undergone ipsilateral cSDH evacuation and traditional ipsilateral MMA embolization allows for over-the-top LE penetration of cSDH membranes, thereby further augmenting the desired ipsilateral MMA embolization.

Background and objectives: Jugular foramen schwannomas (JFS) are rare benign tumors arising from lower cranial nerves. In this study, we aim to compare the outcomes of surgical resection (SR) and stereotactic radiosurgery (SRS) in the treatment of JFS.

Methods: We conducted a retrospective analysis of 31 patients with JFS who underwent SRS (13 patients [41.9%]) or surgical resection (18 patients [58.1%]) as their primary management modality over a two-decade period. Outcomes included progression-free survival, post-treatment adverse events based on Common Terminology Criteria for Adverse Events, symptom improvement, overall survival, and the necessity for secondary interventions. Local tumor control was also evaluated in all patients who received SRS.

Results: Significant differences were observed in baseline characteristics between the SRS and SR groups, including median age (58 vs 48 years, P = .001), largest tumor diameter (32.0 vs 47.5 mm, P = .02), and total tumor volume (6.50 vs 20.5 mm 3 , P = .01). There were no significant differences in sex or lesion morphology (dumbbell vs nondumbbell shaped). After adjusting for baseline characteristics, no significant differences were noted in progression-free survival (90.9 vs 86.2%), overall survival (92.3 vs 100%), symptom improvement (61.5 vs 55.5%), or median Common Terminology Criteria for Adverse Events grade (1 in both groups) between the SRS and SR groups, respectively. SRS patients had significantly lower odds of requiring secondary treatment procedures after their primary intervention as compared with those who underwent SR (odds ratio = 0.02, 95% CI: 0.001-0.88, P -value = .04). Local tumor control in all SRS patients (19 patients) was 93.7% and 79.1% at six-month and five-year time points, respectively.

Conclusion: SRS and SR demonstrate comparable effectiveness in treating JFS. However, SRS may be a more favorable option because of a reduced need for secondary interventions. Future controlled prospective studies are needed to draw more definitive conclusions.