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Pretreatment Electrodiagnostic Evaluation of the Median Nerve Following Distal Radius Fracture. 桡骨远端骨折后正中神经的预处理电诊断评价。
IF 2.1 2区 医学 Q2 ORTHOPEDICS Pub Date : 2026-01-10 DOI: 10.1016/j.jhsa.2025.11.017
Tahsin Aydın, Elif Yalçın Topcuoğlu, Zülüfe Gümüş, İbrahim Alper Yavuz, Fatih İnci, Erman Ceyhan

Purpose: The aim of this research was to evaluate median nerve neuropathy after distal radius fracture (DRF) using nerve conduction studies (NCSs) before and after treatment.

Methods: This prospective follow-up study included 109 patients who were admitted to a level-1 trauma center with DRFs between July 2021 and January 2022, 52 of whom were treated nonsurgically and 57 of whom were treated surgically. Patients who were treated nonsurgically and were suitable for circumferential casting in the emergency department, patients with known median nerve pathology, and patients who underwent procedures other than volar locking plate surgery were excluded. Nerve conduction studies were performed three times: before treatment, at week 6, and at week 12. The relationships between NCS results and demographic (age and sex), therapeutic (treatment method, reduction time, and treatment time), functional (Disabilities of the Arm, Shoulder, and Hand score), and radiological data were evaluated.

Results: Nerve conduction study abnormalities after DRFs were more frequently observed in older patients. In patients undergoing surgical treatment after DRFs, NCS findings indicating median nerve neuropathy were observed more frequently in pretreatment NCSs than in patients treated nonsurgically. However, this difference was not found at the 6- and 12-week NCSs. Median nerve neuropathy findings in pretreatment NCSs were seen more frequently in patients with delayed reduction, but this difference was not observed at the 6- and 12-week NCSs. Disabilities of the Arm, Shoulder, and Hand scores were higher for patients with abnormalities at the pretreatment and 12-week NCSs. There was no difference in NCS findings between radiological parameters or sex.

Conclusions: Age was a risk factor for median nerve neuropathy after DRFs. Delayed reduction was associated with median nerve neuropathy but resolved spontaneously within 6-12 weeks. Early median nerve neuropathy is more common with severe fracture types that usually require surgical intervention.

Type of study/level of evidence: Prognosis IV.

目的:本研究的目的是通过神经传导研究(NCSs)评估桡骨远端骨折(DRF)治疗前后的正中神经病变。方法:本前瞻性随访研究纳入了109例2021年7月至2022年1月间因DRFs入住一级创伤中心的患者,其中52例接受非手术治疗,57例接受手术治疗。排除了非手术治疗且适合在急诊科进行周向铸造的患者、已知正中神经病变的患者以及接受掌侧锁定钢板手术以外手术的患者。神经传导研究进行了三次:治疗前、第6周和第12周。评估NCS结果与人口统计学(年龄和性别)、治疗(治疗方法、复位时间和治疗时间)、功能(手臂、肩部和手部残疾评分)和放射学数据之间的关系。结果:DRFs后神经传导研究异常在老年患者中更为常见。在DRFs后接受手术治疗的患者中,预处理NCS患者比非手术治疗患者更频繁地观察到正中神经病变的NCS结果。然而,在第6周和第12周的ncs中没有发现这种差异。在延迟复位的ncs患者中,预处理ncs的正中神经病变更常见,但在6周和12周的ncs中没有观察到这种差异。在预处理和12周ncs时出现异常的患者,手臂、肩部和手部的残疾评分更高。NCS结果在放射学参数和性别之间没有差异。结论:年龄是DRFs后正中神经病变的危险因素。延迟复位与正中神经病变相关,但在6-12周内自行消退。早期正中神经病变在严重骨折类型中更为常见,通常需要手术干预。研究类型/证据水平:预后IV。
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引用次数: 0
Total Wrist Arthroplasty. 全腕关节置换术。
IF 2.1 2区 医学 Q2 ORTHOPEDICS Pub Date : 2026-01-10 DOI: 10.1016/j.jhsa.2025.11.022
Christopher J Lama, Daniel A Portney, Arnold-Peter C Weiss

Total wrist arthroplasty has undergone substantial evolution in indications, implant design, and expected functional outcomes over the past decade. Osteoarthritis has overtaken rheumatoid arthritis as the major underlying etiology for joint replacement. Patient expectations have also evolved with a trend toward motion-preserving procedures. Finally, implant design based on careful experimental research efforts has assisted in outcome optimization. This article reviews these points in greater depth and provides examples and some technical points for the interested hand surgeon to consider.

在过去的十年中,全腕关节置换术在适应症、植入物设计和预期的功能结果方面经历了实质性的发展。骨关节炎已经取代类风湿关节炎成为关节置换术的主要潜在病因。病人的期望也随着运动保留手术的趋势而发展。最后,基于仔细实验研究的植入物设计有助于优化结果。这篇文章更深入地回顾了这些要点,并提供了一些例子和一些技术要点,供有兴趣的手外科医生考虑。
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引用次数: 0
Arthroscopic Management of Intraarticular Distal Radius Fractures: A Step-by-Step Approach. 关节镜治疗桡骨远端关节内骨折:一步一步的方法。
IF 2.1 2区 医学 Q2 ORTHOPEDICS Pub Date : 2026-01-09 DOI: 10.1016/j.jhsa.2025.07.028
Gustavo L Gomez Rodriguez, Francisco R Melibosky, Sze Ryn Chung, Sanjeev Kakar

The traditional management of distal radius fractures involves the use of fluoroscopy or capsulotomy to guide articular reduction. Arthroscopy is a tool that can aid in achieving articular congruity as well as the management of concomitant injuries, where indicated. In this article, we present a practical arthroscopic step-by-step guide in the treatment of distal radius fractures.

桡骨远端骨折的传统治疗包括使用透视或关节囊切开术来指导关节复位。关节镜检查是一种工具,可以帮助实现关节一致性,并在必要时处理伴随损伤。在这篇文章中,我们提出了一个实用的关节镜逐步指导桡骨远端骨折的治疗。
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引用次数: 0
Accuracy of Implant Placement Using Augmented Reality-assisted Technique in Total Wrist Arthroplasty. 增强现实辅助技术在全腕关节置换术中植入物放置的准确性。
IF 2.1 2区 医学 Q2 ORTHOPEDICS Pub Date : 2026-01-08 DOI: 10.1016/j.jhsa.2025.11.015
Shimpei Watanabe, Takuji Iwamoto, Atsushi Tanji, Yasuhiro Kiyota, Taku Suzuki, Takeo Nagura, Masaya Nakamura

Purpose: The study aimed to evaluate the accuracy of augmented reality-assisted total wrist arthroplasty (AR-TWA) in a cadaveric model using a three-point registration method. The hypothesis is that AR-assisted surgery can enable surgeons to achieve accurate implant placement comparable with surgeries performed under specialist guidance.

Methods: Fourteen fresh-frozen upper extremities from seven cadavers were used for TWA. Computed tomography data were imported into three-dimensional image analysis software for surgical planning. On one side, AR-TWA was performed by a board-certified orthpaedic surgeon with no clinical experience in TWA, and on the contralateral side, non-AR-TWA was performed by the same surgeon under the guidance of an experienced hand surgeon. The accuracy of implant placement was assessed by comparing preoperative and postoperative computed tomography scans and measuring deviations and angular errors between the planned and actual component positions.

Results: For both the radial and carpal components, four of six parameters demonstrated smaller errors in the AR-TWA. Although certain parameters favored the non-AR-TWA, overall variability was lower with AR. When classified as acceptable or outlier, all seven radial cases in the AR-TWA were acceptable for deviation, and six were acceptable for angular error, indicating better consistency than the non-AR-TWA. On the carpal side, AR-TWA demonstrated higher accuracy than non-AR-TWA, but more outliers were observed, suggesting relatively greater variability in this region.

Conclusions: Augmented reality-assisted TWA using a three-point registration method improved the accuracy of implant placement, even when performed by a less experienced surgeon.

Clinical relevance: Augmented reality technology may assist less experienced surgeons in performing technically demanding procedures, such as TWA, with improved accuracy.

目的:本研究旨在利用三点配准法评估增强现实辅助全腕关节置换术(AR-TWA)在尸体模型中的准确性。假设是ar辅助手术可以使外科医生实现与在专家指导下进行的手术相当的准确植入物放置。方法:采用7具尸体的14条新鲜冷冻上肢进行TWA。将计算机断层扫描数据导入三维图像分析软件进行手术计划。在一侧,AR-TWA由一名没有TWA临床经验的委员会认证的骨科医生进行,在对侧,非AR-TWA由同一名外科医生在一名经验丰富的手外科医生的指导下进行。通过比较术前和术后计算机断层扫描以及测量计划和实际组件位置之间的偏差和角度误差来评估种植体放置的准确性。结果:对于桡骨和腕关节,6个参数中的4个在AR-TWA中显示出较小的误差。虽然某些参数有利于非AR- twa,但AR的总体变异性较低。当被分类为可接受或异常值时,AR- twa的所有7个径向病例的偏差都是可接受的,6个角度误差是可接受的,表明一致性优于非AR- twa。在腕侧,AR-TWA显示出比非AR-TWA更高的准确性,但观察到更多的异常值,表明该区域的变异性相对较大。结论:使用三点配准方法的增强现实辅助TWA提高了种植体放置的准确性,即使是由经验不足的外科医生进行。临床意义:增强现实技术可以帮助经验不足的外科医生进行技术要求高的手术,如TWA,并提高准确性。
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引用次数: 0
Radiographic Characteristics of Carpal Instability Associated With Scaphotrapeziotrapezoid Osteoarthritis. 腕关节不稳合并舟状方椎体骨关节炎的影像学特征。
IF 2.1 2区 医学 Q2 ORTHOPEDICS Pub Date : 2026-01-08 DOI: 10.1016/j.jhsa.2025.11.018
Yasunori Hattori, Jun Sasaki, Sotetsu Sakamoto, Ian Magtoto, Ayumi Suzuki, Kazuteru Doi

Purpose: Scaphotrapeziotrapezoid osteoarthritis (STT-OA) may be related to the progression of carpal instability. This study analyzed the radiographic carpal indices in wrists with varying grades of STT-OA to investigate an association between the severity of STT-OA and the occurrence of dorsal intercalated segment instability (DISI), and to identify radiographic characteristics of carpal instability associated with STT-OA.

Methods: We retrospectively measured carpal indices in 135 wrists with STT-OA (Crosby's classification grade 2, 62; grade 3, 73). Carpal indices measured included radiolunate (RL), radioscaphoid (RS), scapholunate (SL), and lunocapitate (LC) angles and SL distance. We compared the values of these carpal indices and the occurrence of DISI between the STT-OA grade 2 and grade 3 groups. We evaluated the presence of radiographic OA in other joints. In the wrists with DISI, we further investigated the relationship between the RL angle and other carpal angles.

Results: The RL and RS angles of grade 3 patients with STT-OA were smaller than those of grade 2 patients. The LC angle of grade 3 was greater than that of grade 2. DISI was identified in 3 grade 2 wrists (5%), and 44 grade 3 wrists (60%). None of the wrists had an SL angle >70°, a widened SL distance (>3mm), or radiographic OA in the RS joint. In the 47 wrists with DISI, there was a negative correlation between RL and LC angles, and positive correlation between RL and RS angles.

Conclusions: We found an association between the severity of STT-OA and occurrence of DISI, and identified unique characteristics of this carpal instability, which include an extended position of the scaphoid, a normal SL angle, and no development of RS-OA.

Type of study/level of evidence: Differential diagnosis/symptom prevalence study IV.

目的:舟状梯形骨关节炎(STT-OA)可能与腕关节不稳定的进展有关。本研究分析了不同级别STT-OA腕关节的x线片腕关节指数,以探讨STT-OA严重程度与背侧插入节段不稳定(DISI)发生之间的关系,并确定STT-OA相关腕关节不稳定的x线片特征。方法:我们回顾性地测量了135例STT-OA患者腕关节指数(Crosby分级2,62;分级3,73)。腕指数测量包括桡月骨(RL)、桡舟骨(RS)、舟月骨(SL)和月头骨(LC)角度和SL距离。我们比较了STT-OA 2级组和3级组腕关节指数和DISI的发生情况。我们评估了其他关节的骨关节炎影像学表现。在DISI腕关节中,我们进一步研究了RL角和其他腕角之间的关系。结果:STT-OA 3级患者的RL和RS角均小于2级患者。3级的LC角大于2级。2级手腕3例(5%),3级手腕44例(60%)。所有腕关节均无左旋角70°,左旋距离增宽3mm, RS关节无骨性关节炎。在47例DISI腕关节中,RL与LC角呈负相关,RL与RS角呈正相关。结论:我们发现STT-OA的严重程度与DISI的发生之间存在关联,并确定了这种腕不稳定的独特特征,包括舟状骨位置延伸,正常的SL角,没有RS-OA的发展。研究类型/证据水平:鉴别诊断/症状流行研究IV。
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引用次数: 0
Intervention-Free Survival Analysis Following Corticosteroid Injection in First Dorsal Compartment Tendonitis. 第一背间室肌腱炎注射皮质类固醇后无干预生存分析。
IF 2.1 2区 医学 Q2 ORTHOPEDICS Pub Date : 2026-01-08 DOI: 10.1016/j.jhsa.2025.11.013
Joshua K Kim, Suhail K Mithani, Warren C Hammert

Purpose: First dorsal compartment tendonitis is a common cause of radial wrist pain. Initial treatments include corticosteroid injections, bracing, and anti-inflammatory medications, with surgical release reserved for persistent symptoms. This study investigated the efficacy of injections and intervention-free survival time.

Methods: Patients at a single academic institution with first dorsal compartment tendonitis treated with at least one corticosteroid injection between 2014 and 2024 were included. Primary events were defined as a repeat injection or operative release. Time between injection and primary event was recorded and analyzed using the Kaplan-Meier product limit method.

Results: Overall, 2,122 hands received a corticosteroid injection for first dorsal compartment tendonitis. With one injection, 66.5% of cases had no further intervention, which increased to 81.0% with two injections. Following an initial injection, 6.7% of cases progressed to surgery at a median of 111 days, and 26.8% had repeat injections. Intervention-free rates were 97% at 6 weeks, 87% at 3 months, and 75% at 6 months. After a second injection, 18.8% had a third injection at a median of 122 days, and 33.6% underwent surgical release. In the group with more than one injection, intervention-free rates were 97% at 6 weeks, 85% at 3 months, and 64% at 6 months.

Conclusions: A high proportion of patients with first dorsal compartment tendonitis appear to have symptom relief in response to corticosteroid injections. A second corticosteroid injection is less effective in reducing the need for operative release or repeat injection. Patients with first dorsal compartment tendonitis should be advised that corticosteroid injections generally provide relief and mitigate the need for repeat interventions.

Type of study/level of evidence: Prognostic IV.

目的:第一背间室肌腱炎是桡腕关节疼痛的常见原因。初始治疗包括皮质类固醇注射、支具和抗炎药物,对持续症状保留手术释放。本研究考察了注射的疗效和无干预生存时间。方法:纳入2014年至2024年间在单一学术机构接受至少一次皮质类固醇注射治疗的第一背间室肌腱炎患者。主要事件定义为重复注射或手术释放。使用Kaplan-Meier积极限法记录和分析注射与主要事件之间的时间。结果:总的来说,2122只手因第一背间室肌腱炎接受了皮质类固醇注射。注射一次后,66.5%的患者无需进一步干预,注射两次后,这一比例上升至81.0%。在首次注射后,6.7%的病例在中位111天进展到手术,26.8%的病例再次注射。6周无干预率为97%,3个月为87%,6个月为75%。第二次注射后,18.8%的患者在122天内进行了第三次注射,33.6%的患者接受了手术释放。在一次以上注射组中,6周无干预率为97%,3个月为85%,6个月为64%。结论:高比例的第一背间室肌腱炎患者似乎对皮质类固醇注射有症状缓解。第二次皮质类固醇注射在减少手术释放或重复注射方面效果较差。第一背间室肌腱炎患者应被告知,皮质类固醇注射通常提供缓解和减少重复干预的需要。研究类型/证据水平:预后IV。
{"title":"Intervention-Free Survival Analysis Following Corticosteroid Injection in First Dorsal Compartment Tendonitis.","authors":"Joshua K Kim, Suhail K Mithani, Warren C Hammert","doi":"10.1016/j.jhsa.2025.11.013","DOIUrl":"https://doi.org/10.1016/j.jhsa.2025.11.013","url":null,"abstract":"<p><strong>Purpose: </strong>First dorsal compartment tendonitis is a common cause of radial wrist pain. Initial treatments include corticosteroid injections, bracing, and anti-inflammatory medications, with surgical release reserved for persistent symptoms. This study investigated the efficacy of injections and intervention-free survival time.</p><p><strong>Methods: </strong>Patients at a single academic institution with first dorsal compartment tendonitis treated with at least one corticosteroid injection between 2014 and 2024 were included. Primary events were defined as a repeat injection or operative release. Time between injection and primary event was recorded and analyzed using the Kaplan-Meier product limit method.</p><p><strong>Results: </strong>Overall, 2,122 hands received a corticosteroid injection for first dorsal compartment tendonitis. With one injection, 66.5% of cases had no further intervention, which increased to 81.0% with two injections. Following an initial injection, 6.7% of cases progressed to surgery at a median of 111 days, and 26.8% had repeat injections. Intervention-free rates were 97% at 6 weeks, 87% at 3 months, and 75% at 6 months. After a second injection, 18.8% had a third injection at a median of 122 days, and 33.6% underwent surgical release. In the group with more than one injection, intervention-free rates were 97% at 6 weeks, 85% at 3 months, and 64% at 6 months.</p><p><strong>Conclusions: </strong>A high proportion of patients with first dorsal compartment tendonitis appear to have symptom relief in response to corticosteroid injections. A second corticosteroid injection is less effective in reducing the need for operative release or repeat injection. Patients with first dorsal compartment tendonitis should be advised that corticosteroid injections generally provide relief and mitigate the need for repeat interventions.</p><p><strong>Type of study/level of evidence: </strong>Prognostic IV.</p>","PeriodicalId":54815,"journal":{"name":"Journal of Hand Surgery-American Volume","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Distal Scaphoid Excision and Triquetrum Excision on Radioscapholunate Fusion: A Systematic Review. 远端舟状骨和三骨瓣切除对桡舟月骨融合的影响:系统综述。
IF 2.1 2区 医学 Q2 ORTHOPEDICS Pub Date : 2026-01-07 DOI: 10.1016/j.jhsa.2025.11.008
Andy Nie, Sarah C Woodford, Dale Robinson, Stephen K Tham, Eugene T Ek, David C Ackland

Purpose: Radioscapholunate (RSL) fusion is a motion-preserving limited wrist fusion treatment option for symptomatic radiocarpal arthritis; however, there is no consensus regarding the need for excision of the distal scaphoid or triquetrum. This study aimed to determine the impact of distal scaphoid excision (DSE) and triquetrum excision (TE) in RSL fusion and compare the outcomes and complications.

Methods: A systematic review of the literature was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, and relevant clinical studies on RSL fusion were retrieved from Scopus, MEDLINE, and Embase. Meta-analysis with a random-effects model was used to assess the functional and clinical outcomes, including range of motion; grip strength; Disabilities of Arm, Shoulder, and Hand scores; visual analog scale pain scores; and Patient-Rated Wrist Evaluation scores. The rates of complications were analyzed.

Results: The analysis included a total of 24 studies involving 477 wrists, of which, 49% had RSL fusion alone, 41% had RSL fusion with DSE, and 10% had RSL fusion with DSE and TE. Meta-analysis demonstrated improved postoperative flexion and radial deviation in wrists with DSE compared to those without, by 8° and 3°, respectively. The incidence of nonunion was significantly lower in wrists with DSE and wrists with DSE and TE. The incidence of secondary midcarpal osteoarthritis was the lowest in wrists with DSE, but highest in wrists with DSE and TE.

Conclusions: Excision of the distal scaphoid resulted in slightly increased ranges of wrist flexion and radial deviation and reduced the rates of nonunion and secondary midcarpal osteoarthritis in RSL fusion. Patients who have had combined DSE and TE, demonstrated an increased incidence of secondary midcarpal degeneration.

Type of study/level of evidence: Therapeutic IV.

目的:桡舟月骨(RSL)融合术是治疗症状性桡腕关节炎的一种保留运动的有限手腕融合术;然而,对于是否需要切除远端舟状骨或三角骨尚无共识。本研究旨在确定远端舟状骨切除(DSE)和三骨瓣切除(TE)对RSL融合的影响,并比较结果和并发症。方法:按照系统评价和荟萃分析指南的首选报告项目对文献进行系统综述,并从Scopus、MEDLINE和Embase检索RSL融合的相关临床研究。采用随机效应模型进行meta分析,评估功能和临床结果,包括活动范围;握力;手臂、肩部和手部残疾评分;视觉模拟量表疼痛评分;以及患者腕部评估评分。分析并发症发生率。结果:本分析共纳入24项研究,涉及477个腕关节,其中49%的患者单独行RSL融合,41%的患者行RSL融合DSE, 10%的患者行RSL融合DSE和TE。荟萃分析显示,与没有DSE的患者相比,DSE患者的腕关节术后屈曲和桡骨偏差分别改善了8°和3°。伴有DSE的手腕和伴有DSE和TE的手腕不愈合的发生率明显较低。继发性腕中骨关节炎的发生率在DSE患者腕部最低,但在DSE和TE患者腕部最高。结论:切除舟状骨远端可轻微增加腕关节屈曲和桡骨偏移的范围,降低RSL融合术中不愈合和继发性腕中骨关节炎的发生率。合并DSE和TE的患者显示继发性腕中退变的发生率增加。研究类型/证据水平:治疗性IV。
{"title":"The Effect of Distal Scaphoid Excision and Triquetrum Excision on Radioscapholunate Fusion: A Systematic Review.","authors":"Andy Nie, Sarah C Woodford, Dale Robinson, Stephen K Tham, Eugene T Ek, David C Ackland","doi":"10.1016/j.jhsa.2025.11.008","DOIUrl":"https://doi.org/10.1016/j.jhsa.2025.11.008","url":null,"abstract":"<p><strong>Purpose: </strong>Radioscapholunate (RSL) fusion is a motion-preserving limited wrist fusion treatment option for symptomatic radiocarpal arthritis; however, there is no consensus regarding the need for excision of the distal scaphoid or triquetrum. This study aimed to determine the impact of distal scaphoid excision (DSE) and triquetrum excision (TE) in RSL fusion and compare the outcomes and complications.</p><p><strong>Methods: </strong>A systematic review of the literature was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, and relevant clinical studies on RSL fusion were retrieved from Scopus, MEDLINE, and Embase. Meta-analysis with a random-effects model was used to assess the functional and clinical outcomes, including range of motion; grip strength; Disabilities of Arm, Shoulder, and Hand scores; visual analog scale pain scores; and Patient-Rated Wrist Evaluation scores. The rates of complications were analyzed.</p><p><strong>Results: </strong>The analysis included a total of 24 studies involving 477 wrists, of which, 49% had RSL fusion alone, 41% had RSL fusion with DSE, and 10% had RSL fusion with DSE and TE. Meta-analysis demonstrated improved postoperative flexion and radial deviation in wrists with DSE compared to those without, by 8° and 3°, respectively. The incidence of nonunion was significantly lower in wrists with DSE and wrists with DSE and TE. The incidence of secondary midcarpal osteoarthritis was the lowest in wrists with DSE, but highest in wrists with DSE and TE.</p><p><strong>Conclusions: </strong>Excision of the distal scaphoid resulted in slightly increased ranges of wrist flexion and radial deviation and reduced the rates of nonunion and secondary midcarpal osteoarthritis in RSL fusion. Patients who have had combined DSE and TE, demonstrated an increased incidence of secondary midcarpal degeneration.</p><p><strong>Type of study/level of evidence: </strong>Therapeutic IV.</p>","PeriodicalId":54815,"journal":{"name":"Journal of Hand Surgery-American Volume","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Osteoporosis on Survival of Silicone and Pyrocarbon Metacarpophalangeal Implants in Rheumatoid Arthritis. 骨质疏松对类风湿性关节炎中硅胶和焦碳掌指骨植入物存活的影响。
IF 2.1 2区 医学 Q2 ORTHOPEDICS Pub Date : 2026-01-05 DOI: 10.1016/j.jhsa.2025.11.011
Adam Schluttenhofer, Andy Tom, Alex Yonkman, Marco Rizzo

Purpose: To evaluate the impact of preoperative osteoporosis on rates of revision and reoperation for patients with rheumatoid arthritis (RA) who underwent primary metacarpophalangeal (MCP) arthroplasty with silicone or pyrocarbon implants.

Methods: We retrospectively identified all primary silicone and pyrocarbon MCP arthroplasties performed in patients with RA at our institution over an 18-year period. Patient osteoporosis status was determined according to the National Bone Health Alliance criteria. We report survival free from revision (implant removal or replacement) and all-cause reoperation (including revisions) in these groups. We used cluster-robust, multivariable Cox proportional hazards models to analyze osteoporosis as a risk factor for revision and all-cause reoperation and report subgroup analysis for pyrocarbon and silicone implants.

Results: The osteoporosis group included 200 joints (168 silicone, 32 pyrocarbon) in 56 patients with a mean follow-up of 7.9 years. The nonosteoporosis group included 129 joints (93 silicone, 36 pyrocarbon) in 42 patients with a mean follow-up of 10 years. With pyrocarbon implants, the osteoporosis group had lower 10-year survival free from revision (58% vs 100%) and all-cause reoperation (40% vs. 81%) than the nonosteoporosis group. In multivariable analysis of pyrocarbon implants, osteoporosis was associated with increased hazard for revision (HR, 11.0; 95% CI, 1.27-95.8) and all-cause reoperation (HR, 3.4; 95% CI, 1.2-10.3). With silicone implants, there was no difference in 10-year survival free from revision (88% in osteoporosis, 89% in nonosteoporosis) or all-cause reoperation (85% osteoporosis, 85% nonosteoporosis). Osteoporosis did not affect risk for silicone implant revision or reoperation.

Conclusions: Osteoporosis is associated with increased risk for pyrocarbon implant revision and all-cause reoperation in RA patients, though the precise effect size is unknown. Silicone MCP arthroplasty remains a durable option for patients with RA regardless of osteoporosis status.

Type of study/level of evidence: Therapeutic IV.

目的:评价术前骨质疏松对类风湿性关节炎(RA)患者行硅胶或焦碳假体初级掌指关节置换术(MCP)翻修率和再手术率的影响。方法:我们回顾性分析了我院18年来所有RA患者的硅胶和焦碳MCP置换手术。根据国家骨健康联盟标准确定患者骨质疏松状况。我们报告了这些组中无翻修(植入物移除或置换)和全因再手术(包括翻修)的生存率。我们使用聚类稳健性、多变量Cox比例风险模型分析骨质疏松作为翻修手术和全因再手术的危险因素,并报告了焦碳和硅胶植入物的亚组分析。结果:骨质疏松组包括56例患者的200个关节(168个硅胶关节,32个炭关节),平均随访7.9年。非骨质疏松组包括42例患者的129个关节(93个硅胶关节,36个炭关节),平均随访10年。与非骨质疏松组相比,骨质疏松组无翻修的10年生存率(58%对100%)和全因再手术(40%对81%)较低。在多变量分析中,骨质疏松症与翻修风险增加(HR, 11.0; 95% CI, 1.27-95.8)和全因再手术(HR, 3.4; 95% CI, 1.2-10.3)相关。使用硅胶植入物,无翻修的10年生存率(骨质疏松88%,非骨质疏松89%)或全因再手术(骨质疏松85%,非骨质疏松85%)无差异。骨质疏松不影响硅胶植入物翻修或再手术的风险。结论:骨质疏松症与RA患者热炭植入物翻修和全因再手术的风险增加有关,尽管确切的效应大小尚不清楚。硅胶MCP关节置换术仍然是RA患者的持久选择,无论骨质疏松状况如何。研究类型/证据水平:治疗性IV。
{"title":"The Effect of Osteoporosis on Survival of Silicone and Pyrocarbon Metacarpophalangeal Implants in Rheumatoid Arthritis.","authors":"Adam Schluttenhofer, Andy Tom, Alex Yonkman, Marco Rizzo","doi":"10.1016/j.jhsa.2025.11.011","DOIUrl":"https://doi.org/10.1016/j.jhsa.2025.11.011","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the impact of preoperative osteoporosis on rates of revision and reoperation for patients with rheumatoid arthritis (RA) who underwent primary metacarpophalangeal (MCP) arthroplasty with silicone or pyrocarbon implants.</p><p><strong>Methods: </strong>We retrospectively identified all primary silicone and pyrocarbon MCP arthroplasties performed in patients with RA at our institution over an 18-year period. Patient osteoporosis status was determined according to the National Bone Health Alliance criteria. We report survival free from revision (implant removal or replacement) and all-cause reoperation (including revisions) in these groups. We used cluster-robust, multivariable Cox proportional hazards models to analyze osteoporosis as a risk factor for revision and all-cause reoperation and report subgroup analysis for pyrocarbon and silicone implants.</p><p><strong>Results: </strong>The osteoporosis group included 200 joints (168 silicone, 32 pyrocarbon) in 56 patients with a mean follow-up of 7.9 years. The nonosteoporosis group included 129 joints (93 silicone, 36 pyrocarbon) in 42 patients with a mean follow-up of 10 years. With pyrocarbon implants, the osteoporosis group had lower 10-year survival free from revision (58% vs 100%) and all-cause reoperation (40% vs. 81%) than the nonosteoporosis group. In multivariable analysis of pyrocarbon implants, osteoporosis was associated with increased hazard for revision (HR, 11.0; 95% CI, 1.27-95.8) and all-cause reoperation (HR, 3.4; 95% CI, 1.2-10.3). With silicone implants, there was no difference in 10-year survival free from revision (88% in osteoporosis, 89% in nonosteoporosis) or all-cause reoperation (85% osteoporosis, 85% nonosteoporosis). Osteoporosis did not affect risk for silicone implant revision or reoperation.</p><p><strong>Conclusions: </strong>Osteoporosis is associated with increased risk for pyrocarbon implant revision and all-cause reoperation in RA patients, though the precise effect size is unknown. Silicone MCP arthroplasty remains a durable option for patients with RA regardless of osteoporosis status.</p><p><strong>Type of study/level of evidence: </strong>Therapeutic IV.</p>","PeriodicalId":54815,"journal":{"name":"Journal of Hand Surgery-American Volume","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145901722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Edema on Flexor Tendon Tensile Forces Following Zone II Repair: A Biomechanical Analysis in a Cadaveric Model. II区修复后水肿对屈肌腱张力的影响:尸体模型的生物力学分析。
IF 2.1 2区 医学 Q2 ORTHOPEDICS Pub Date : 2026-01-03 DOI: 10.1016/j.jhsa.2025.12.001
Eric R Taleghani, Sean Bucherl, Ryan Davenport, Isaac Hale, Eric Nauman, Kagan Ozer

Purpose: The effect of digital edema on tensile forces in zone II flexor tendon injuries has not been extensively investigated. The purpose of this study was to examine the effect of digital edema on flexor tensile forces following six-strand repair of a zone II flexor tendon laceration and to assess how these forces change throughout the total arc of motion.

Methods: Eight cadaveric upper extremities were used in the study. All specimens were placed in a dorsal blocking splint with the wrist in neutral and metacarpophalangeal joints at 45° of flexion. Continuous force-displacement curves were generated for the following experimental conditions: at baseline; following zone II flexor digitorum profundus six-strand repair, with mild, moderate, and severe edema; and with self-adherent wrap in place. The force required to produce 3 millimeters of tendon gap was measured as the load to failure in this model. A linear mixed effect model was used to evaluate differences in average flexion force among experimental groups.

Results: The average peak force to achieve 270° of flexion for each experimental condition was 10.3 N, 16.1 N, 21.4 N, 28.1 N, 34.3 N, and 47.5 N. The average load to failure was 44.6 N. Digital flexion forces increased nonlinearly throughout the arc of motion. At 180°, moderate edema, severe edema, and self-adherent wrap resulted in significantly increased tensile forces compared to the control and postrepair measurements.

Conclusions: Flexion forces increase exponentially throughout the arc of motion and increase significantly with moderate and severe edema beyond 180° in this model. In the setting of moderate to severe edema, active flexion should be limited to the first half of the arc of motion.

Clinical relevance: This is a biomechanical study that quantifies the effect of edema and self-adherent wrap on flexor tendon tensile forces throughout the arc of motion. The patient and therapist should be aware of this kinetic pattern to avoid complications after surgery.

目的:手指水肿对II区屈肌腱损伤的张力的影响还没有广泛的研究。本研究的目的是研究II区屈肌腱撕裂伤六股修复后手指水肿对屈肌腱张力的影响,并评估这些力在整个运动弧度中如何变化。方法:采用8具尸体上肢进行研究。所有标本置于背侧阻断夹板中,腕关节处于中性,掌指关节屈曲45°。在以下实验条件下,生成连续的力-位移曲线:基线;后II区指深屈肌六股修复,轻度、中度和重度水肿;并将自粘膜贴好。在该模型中,测量产生3毫米肌腱间隙所需的力作为失效载荷。采用线性混合效应模型评价各组平均挠曲力的差异。结果:在每个实验条件下,实现270°屈曲的平均峰值力为10.3 N, 16.1 N, 21.4 N, 28.1 N, 34.3 N和47.5 N,到失效的平均载荷为44.6 N,数字屈曲力在整个运动弧度中呈非线性增加。在180°时,与对照组和修复后的测量结果相比,中度水肿、重度水肿和自粘附包裹导致张力显著增加。结论:在该模型中,屈曲力在整个运动弧度呈指数增长,在180°以上的中度和重度水肿时显著增加。在中度至重度水肿的情况下,主动屈曲应限制在活动弧度的前半部分。临床相关性:这是一项生物力学研究,量化了水肿和自粘附膜在整个运动弧度中对屈肌腱张力的影响。患者和治疗师应注意这种运动模式,以避免术后并发症。
{"title":"Effect of Edema on Flexor Tendon Tensile Forces Following Zone II Repair: A Biomechanical Analysis in a Cadaveric Model.","authors":"Eric R Taleghani, Sean Bucherl, Ryan Davenport, Isaac Hale, Eric Nauman, Kagan Ozer","doi":"10.1016/j.jhsa.2025.12.001","DOIUrl":"https://doi.org/10.1016/j.jhsa.2025.12.001","url":null,"abstract":"<p><strong>Purpose: </strong>The effect of digital edema on tensile forces in zone II flexor tendon injuries has not been extensively investigated. The purpose of this study was to examine the effect of digital edema on flexor tensile forces following six-strand repair of a zone II flexor tendon laceration and to assess how these forces change throughout the total arc of motion.</p><p><strong>Methods: </strong>Eight cadaveric upper extremities were used in the study. All specimens were placed in a dorsal blocking splint with the wrist in neutral and metacarpophalangeal joints at 45° of flexion. Continuous force-displacement curves were generated for the following experimental conditions: at baseline; following zone II flexor digitorum profundus six-strand repair, with mild, moderate, and severe edema; and with self-adherent wrap in place. The force required to produce 3 millimeters of tendon gap was measured as the load to failure in this model. A linear mixed effect model was used to evaluate differences in average flexion force among experimental groups.</p><p><strong>Results: </strong>The average peak force to achieve 270° of flexion for each experimental condition was 10.3 N, 16.1 N, 21.4 N, 28.1 N, 34.3 N, and 47.5 N. The average load to failure was 44.6 N. Digital flexion forces increased nonlinearly throughout the arc of motion. At 180°, moderate edema, severe edema, and self-adherent wrap resulted in significantly increased tensile forces compared to the control and postrepair measurements.</p><p><strong>Conclusions: </strong>Flexion forces increase exponentially throughout the arc of motion and increase significantly with moderate and severe edema beyond 180° in this model. In the setting of moderate to severe edema, active flexion should be limited to the first half of the arc of motion.</p><p><strong>Clinical relevance: </strong>This is a biomechanical study that quantifies the effect of edema and self-adherent wrap on flexor tendon tensile forces throughout the arc of motion. The patient and therapist should be aware of this kinetic pattern to avoid complications after surgery.</p>","PeriodicalId":54815,"journal":{"name":"Journal of Hand Surgery-American Volume","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145892770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Vivo Tracking of Amniotic Fluid Derived Stem Cells on Acellular Nerve Graft 羊水干细胞在脱细胞神经移植中的体内追踪。
IF 2.1 2区 医学 Q2 ORTHOPEDICS Pub Date : 2026-01-01 DOI: 10.1016/j.jhsa.2025.02.012
Xue Ma MD, PhD , Kaitlin Henry BS , Kelsey Healy BS , Tianyi David Luo MD, PhD , Thomas L. Smith PhD , Zhongyu Li MD, PhD

Purpose

This study aimed to track amniotic fluid derived stem (AFS) cells that are seeded into nerve allografts, and to elucidate the potential mechanisms of their impact on the regenerating nerve.

Methods

Amniotic fluid derived stem cells were labeled using supra-paramagnetic micrometer-sized iron oxide (MPIO) and assessed for viability. Cells were cultured in neurogenic induction media and evaluated for neurogenic growth factors. Differentiated cells were confirmed with reverse transcription-polymerase chain reaction for neurogenic lineage markers. MPIO labeled AFS cells were injected into an acellular nerve allograft (ANA) to repair sciatic nerve defects in rats. Labeled AFS cells were evaluated using magnetic resonance imaging (MRI) and the intensity of the MPIO regions in the ANA was quantified. Contiguous frozen sections were stained for iron to identify cells incorporated into the nerve graft.

Results

Proliferation rate and morphology between the control and MPIO-labeled cells demonstrated similar patterns. AFS cells differentiated toward Schwann-like cells after being cultured in neurogenic induction media. nerve growth factor (NGF) and neurofilament light chain gene expression were elevated by 202.60 ± 1.89 and 30.62 ± 1.99 times, respectively, compared with control. Cytokine quantification analysis showed significantly increased brain-derived neurotrophic factor, β-NGF, β-fibroblast growth factor, glial cell-derived neurotrophic factor, nerve growth factor receptor, neurotrophin-4, and tumor growth factor β production. 7-Tesla MRI demonstrated MPIO labeling with a strong decrease in the T2-weighted signal. The average normalized hypointense region volume was similar between groups postinjury. Cell integration into ANA was confirmed by iron staining.

Conclusions

AFS cells remained viable after labeling with MPIO and can be used to augment nerve repair by seeding onto ANAs. Cytokine analysis suggests a paracrine-mediated effect of AFS cells on nerve repair following injury. MRI can effectively track the AFS cells longitudinally in the rat model up to 4 weeks postimplantation.

Clinical relevance

The study provides translational evidence on using MRI for tracking AFS cells in the decellularized nerve allografts for nerve repair and regeneration.
目的:本研究旨在追踪播种到神经异体移植中的羊水衍生干细胞(AFS),并阐明其对再生神经影响的潜在机制:方法:使用超顺磁性微米级氧化铁(MPIO)标记羊水衍生干细胞,并评估其存活率。在神经源诱导培养基中培养细胞,并评估神经源生长因子。通过反转录聚合酶链反应确认分化细胞的神经源系标记。将 MPIO 标记的 AFS 细胞注入无细胞神经异体移植(ANA)以修复大鼠坐骨神经缺损。使用磁共振成像(MRI)对标记的 AFS 细胞进行评估,并对 ANA 中 MPIO 区域的强度进行量化。对连续的冷冻切片进行铁染色,以识别纳入神经移植的细胞:结果:对照组和 MPIO 标记细胞的增殖率和形态显示出相似的模式。神经生长因子(NGF)和神经丝蛋白轻链基因表达分别比对照组提高了 202.60 ± 1.89 倍和 30.62 ± 1.99 倍。细胞因子定量分析显示,脑源性神经营养因子、β-NGF、β-成纤维细胞生长因子、胶质细胞源性神经营养因子、神经生长因子受体、神经营养素-4 和肿瘤生长因子 β 的产生量明显增加。7-Tesla 磁共振成像显示 MPIO 标记与 T2 加权信号的强烈减弱。各组损伤后的平均归一化低密度区体积相似。铁染色证实了细胞与ANA的整合:结论:AFS细胞在用MPIO标记后仍然存活,可通过播种到ANA上增强神经修复。细胞因子分析表明,AFS 细胞对损伤后的神经修复具有旁分泌效应。核磁共振成像可有效追踪大鼠模型中的AFS细胞,直至植入后4周:该研究为利用核磁共振成像追踪脱细胞神经异体移植中的 AFS 细胞进行神经修复和再生提供了转化证据。
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Journal of Hand Surgery-American Volume
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