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[25/m-Sexual risk exposure : Preparation for the medical specialist examination: part 114]. [25/m-性风险暴露:为医学专家检查做准备:第114部分]。
4区 医学 Q3 Medicine
Internist
Pub Date : 2022-02-01 Epub Date: 2021-09-01 DOI: 10.1007/s00108-021-01133-7
H Matthews, S Schmiedel
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引用次数: 0
[72/f-Sudden onset of palpitations : Preparation for the medical specialist examination: part 125]. [72/f]突发心悸:为医学专家检查做准备:第125部分]。
4区 医学 Q3 Medicine
Internist
Pub Date : 2022-02-01 Epub Date: 2022-01-20 DOI: 10.1007/s00108-021-01253-0
M Privoznik
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引用次数: 0
[74/f-Vigilance reduction and left-sided hemiparesis : Preparation for the medical specialist examination: part 121]. [74/f]警惕性降低和左侧偏瘫:为医学专家检查做准备:第121部分]。
4区 医学 Q3 Medicine
Internist
Pub Date : 2022-02-01 Epub Date: 2022-01-20 DOI: 10.1007/s00108-021-01252-1
C Bauer-Büntzel, M Abu-Tair
{"title":"[74/f-Vigilance reduction and left-sided hemiparesis : Preparation for the medical specialist examination: part 121].","authors":"C Bauer-Büntzel, M Abu-Tair","doi":"10.1007/s00108-021-01252-1","DOIUrl":"https://doi.org/10.1007/s00108-021-01252-1","url":null,"abstract":"","PeriodicalId":54924,"journal":{"name":"Internist","volume":"63 Suppl 1","pages":"105-109"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39934528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[What should specialist in internal medicine be aware of in patients treated with biologics? : Infections and autoimmune phenomena]. [内科专家在接受生物制剂治疗的患者中应注意什么?]:感染和自身免疫现象]。
4区 医学 Q3 Medicine
Internist
Pub Date : 2022-02-01 Epub Date: 2022-01-28 DOI: 10.1007/s00108-021-01259-8
Thomas Zander, Michael Hallek

Biologics that influence the immune system play a crucial role in the treatment of autoimmune and malignant diseases. Overall these drugs have revolutionized treatment as they demonstrate high efficacy and a relatively low amount of side effects. This leads to longer treatment of patients with a high quality of life. Side effects, especially longer-term side effects, become ever more important as patients are simultaneously seen by different physicians due to comorbidities. Infections, mainly of the upper airway or urogenital tract, represent the main side effect of immunosuppressive biologics, but atypical infections by fungi or mycobacteria may also occur. Biologics that enhance the immune response such as checkpoint inhibitors lead to autoimmune phenomena necessitating the interruption of treatment or immunosuppressive treatment.

影响免疫系统的生物制剂在自身免疫性疾病和恶性疾病的治疗中起着至关重要的作用。总的来说，这些药物已经彻底改变了治疗，因为它们表现出高效率和相对较少的副作用。这使得患者的治疗时间更长，生活质量更高。副作用，特别是长期的副作用，变得越来越重要，因为病人同时看到不同的医生由于合并症。感染，主要是上呼吸道或泌尿生殖道，是免疫抑制生物制剂的主要副作用，但真菌或分枝杆菌的非典型感染也可能发生。增强免疫反应的生物制剂，如检查点抑制剂，会导致自身免疫现象，需要中断治疗或免疫抑制治疗。
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引用次数: 0
[57/m-Hemoptysis : Preparation for the medical specialist examination: part 122]. [57/m-咯血:医学专科检查的准备:第122部分]。
4区 医学 Q3 Medicine
Internist
Pub Date : 2022-02-01 Epub Date: 2021-12-09 DOI: 10.1007/s00108-021-01224-5
E Pappe, R-H Hübner, M Raspe
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引用次数: 0
[32/f-Pain in the right knee : Preparation for the medical specialist examination: part 123]. [32/f-右膝疼痛:医学专家检查的准备:第123部分]。
4区 医学 Q3 Medicine
Internist
Pub Date : 2022-02-01 Epub Date: 2021-09-22 DOI: 10.1007/s00108-021-01140-8
C Meyer-Schwickerath, K Schmidt-Hellerau, N Jung
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引用次数: 0
[35/f-Dry cough, fatigue and weight loss : Preparation for the medical specialist examination: part 116]. [35/f]干咳、疲劳和体重减轻:为医学专家检查做准备:第116部分]。
4区 医学 Q3 Medicine
Internist
Pub Date : 2022-02-01 Epub Date: 2022-01-04 DOI: 10.1007/s00108-021-01216-5
E Büscher, J Wälscher
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引用次数: 0
[35/m-Fatigue, lower abdominal pain and fecal blood : Preparation for the medical specialist examination: part 106]. [35/m-疲劳、下腹痛和粪血:为医学专家检查做准备:第106部分]。
4区 医学 Q3 Medicine
Internist
Pub Date : 2022-02-01 Epub Date: 2021-09-22 DOI: 10.1007/s00108-021-01145-3
U Helwig
{"title":"[35/m-Fatigue, lower abdominal pain and fecal blood : Preparation for the medical specialist examination: part 106].","authors":"U Helwig","doi":"10.1007/s00108-021-01145-3","DOIUrl":"https://doi.org/10.1007/s00108-021-01145-3","url":null,"abstract":"","PeriodicalId":54924,"journal":{"name":"Internist","volume":"63 Suppl 1","pages":"31-34"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39441089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Rare cause of renal infarction in a 28-year-old male patient]. 【一例28岁男性肾梗死的罕见病因】。
4区 医学 Q3 Medicine
Internist
Pub Date : 2022-02-01 Epub Date: 2021-10-15 DOI: 10.1007/s00108-021-01186-8
Dimitrios David Papazoglou, Salome Weiss, Pascal Kissling

This article presents the case of a 28-year-old male patient with a renal infarction due to an embolizing traumatic postdissection aneurysm of a renal segmental artery. He presented with abdominal and flank pain 1.5 years after a motorcycle accident. The C‑reactive protein (CRP) and lactate dehydrogenase (LDH) levels were elevated and the diagnosis was made by computed tomography (CT) angiography. Other causes of renal infarction were excluded. After an interdisciplinary discussion we decided to use interventional coiling in this young and athletically active patient in order to avoid long-term anticoagulation.

这篇文章提出的情况下，28岁的男性患者肾梗死由于栓塞创伤后肾节段动脉动脉瘤。他在一次摩托车事故1.5年后出现腹部和腹部疼痛。C反应蛋白(CRP)和乳酸脱氢酶(LDH)水平升高，并通过计算机断层扫描(CT)血管造影进行诊断。排除其他肾梗死原因。经过跨学科的讨论，我们决定对这名年轻且运动活跃的患者使用介入盘绕，以避免长期抗凝。
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引用次数: 0
[Acute porphyrias viewed differently]. [对急性卟啉症的不同看法]。
4区 医学 Q3 Medicine
Internist
Pub Date : 2022-02-01 Epub Date: 2021-11-11 DOI: 10.1007/s00108-021-01203-w
Jasmin Barman-Aksözen, Anna-Elisabeth Minder

The acute porphyrias are a group of four metabolic defects in which the heme synthesis in the liver is disrupted. They are characterized by massively painful acute attacks, which can be life-threatening if not diagnosed. To raise the awareness for these rare disorders, a heme molecule in cartoon style is introduced, which accurately explains the basic biochemical processes in the body and mediates important information on the acute hepatic porphyrias in a simplified and attractive way. The article is complemented by a case report.

急性卟啉症是一组四种代谢缺陷，其中肝脏中的血红素合成被破坏。它们的特点是剧烈疼痛的急性发作，如果不及时诊断，可能危及生命。为了提高人们对这些罕见疾病的认识，本文介绍了一种卡通风格的血红素分子，它准确地解释了体内的基本生化过程，并以简化和吸引人的方式介导了有关急性肝性卟啉症的重要信息。这篇文章附有一份病例报告。
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引用次数: 0
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