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German Pharmaceutical Pricing: Lessons for the United States. 德国药品定价:给美国的教训。
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2021-10-20 DOI: 10.1177/00207314211040948
Marc A Rodwin, Sara Gerke

To control pharmaceutical spending and improve access, the United States could adopt strategies similar to those introduced in Germany by the 2011 German Pharmaceutical Market Reorganization Act. In Germany, manufacturers sell new drugs immediately upon receiving marketing approval. During the first year, the German Federal Joint Committee assesses new drugs to determine their added medical benefit. It assigns them a score indicating their added benefit. New drugs comparable to drugs in a reference price group are assigned to that group and receive the same reimbursement, unless they are therapeutically superior. The National Association of Statutory Health Insurance Funds then negotiates with manufacturers the maximum reimbursement starting the 13th month, consistent with the drug's added benefit assessment and price caps in other European countries. In the absence of agreement, an arbitration board sets the price. Manufacturers accept the price resolution or exit the market. Thereafter, prices generally are not increased, even for inflation. US public and private insurers control prices in diverse ways, but typically obtain discounts by designating certain drugs as preferred and by restricting patient access or charging high copayment for nonpreferred drugs. This article draws 10 lessons for drug pricing reform in US federal programs and private insurance.

为了控制药品支出和改善获取途径,美国可以采取与德国2011年《德国药品市场重组法案》类似的策略。在德国,制造商在获得市场批准后立即销售新药。在第一年,德国联邦联合委员会对新药进行评估,以确定其附加的医疗效益。它会给他们一个分数,表明他们的额外收益。与参考价格组中的药物相当的新药被分配到该组并获得相同的报销,除非它们在治疗上更优越。国家法定健康保险基金协会随后与制造商协商从第13个月开始的最高报销金额,与其他欧洲国家的药品附加效益评估和价格上限保持一致。在没有达成协议的情况下,由仲裁委员会确定价格。制造商要么接受价格解决方案,要么退出市场。此后,即使考虑到通货膨胀,价格一般也不会上涨。美国的公共和私营保险公司以不同的方式控制价格,但通常通过指定某些药物为首选药物、限制患者使用或对非首选药物收取高额共同费用来获得折扣。本文为美国联邦计划和私人保险的药品定价改革提供了10条经验教训。
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引用次数: 3
Health Shocks and Unbalanced Growth of Medical Resources: Evidence From the SARS Epidemic in China. 健康冲击与医疗资源不平衡增长:来自中国SARS疫情的证据。
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2021-01-10 DOI: 10.1177/0020731420978871
Juan Wang, Hantao Wu
Since the outbreak of the SARS epidemic in 2003, the Chinese government has increased inputs to bolster the health care system. However, the COVID-19 pandemic has exposed the geographic maldistribution of health resources in China. We examine the spatial and temporal variation of the SARS epidemic using a difference-in-differences strategy. Our empirical results show that, compared with cities without SARS case reports, exogenous health shocks significantly increased the affected cities' medical resources supply. We provide multiple robustness tests to examine the validity of the main findings. Further study shows that the mechanism is because the SARS event increased the financial autonomy of the epidemic-affected cities, thus providing an incentive for local governments to increase health resources. Meanwhile, health shocks have little influence on the regions with only imported cases than the infected area. These findings provide a possible explanation for the inequality in the distribution of health resources.
自2003年非典疫情爆发以来,中国政府加大了对医疗卫生体系的投入。然而,新冠肺炎疫情暴露了中国卫生资源的地域分布不均。我们使用差异中的差异策略检查了SARS流行的时空变化。实证结果表明,与未报告SARS病例的城市相比,外源性卫生冲击显著增加了受影响城市的医疗资源供给。我们提供了多个稳健性测试来检验主要发现的有效性。进一步的研究表明,其机制是由于SARS事件增加了疫情城市的财政自主权,从而为地方政府增加卫生资源提供了激励。与此同时,卫生冲击对只有输入病例的地区的影响小于感染地区。这些发现为卫生资源分配不平等提供了可能的解释。
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引用次数: 2
Effectiveness of Government Policies in Controlling COVID-19 in India. 印度政府防控新冠肺炎政策的有效性
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2020-12-29 DOI: 10.1177/0020731420983749
Ashutosh Pandey, Nitin Kishore Saxena

The purpose of this study is to find the demographic factors associated with the spread of COVID-19 and to suggest a measure for identifying the effectiveness of government policies in controlling COVID-19. The study hypothesizes that the cumulative number of confirmed COVID-19 patients depends on the urban population, rural population, number of persons older than 50, population density, and poverty rate. A log-linear model is used to test the stated hypothesis, with the cumulative number of confirmed COVID-19 patients up to period t as a dependent variable and demographic factors as an independent variable. The policy effectiveness indicator is calculated by taking the difference of the COVID rank of the ith state based on the predicted model and the actual COVID rank of the ith state. Our study finds that the urban population significantly impacts the spread of COVID-19. On the other hand, demographic factors such as rural population, density, and age structure do not impact the spread of COVID-19 significantly. Thus, people residing in urban areas face a significant threat of COVID-19 as compared to people in rural areas.

本研究的目的是找出与COVID-19传播相关的人口因素,并提出一种衡量政府政策控制COVID-19有效性的措施。该研究假设,新冠肺炎累计确诊人数取决于城市人口、农村人口、50岁以上人口、人口密度和贫困率。使用对数线性模型来检验所述假设,以截至t期的COVID-19确诊患者累计人数为因变量,人口统计学因素为自变量。政策有效性指标是根据预测模型计算的第i个州的COVID排名与第i个州的实际COVID排名之差计算得出的。我们的研究发现,城市人口对COVID-19的传播有显著影响。另一方面,农村人口、密度、年龄结构等人口因素对新冠病毒的传播影响不大。因此,与农村地区相比,居住在城市地区的人面临着COVID-19的重大威胁。
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引用次数: 9
Mandatory Public Health Measures for Coronavirus-19 Are Associated With Improved Mortality, Equity and Economic Outcomes. 针对冠状病毒19的强制性公共卫生措施与改善死亡率、公平和经济成果有关。
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2021-10-21 DOI: 10.1177/00207314211049306
Brita Lundberg, Kathryn McDonald

The impact of public health measures on the coronavirus-2019 pandemic was analyzed by comparing mandatory versus voluntary nonpharmaceutical interventions between 2 comparable European countries and among 3 U.S. states. Using an ecological retrospective cohort study design, we examine differences in mortality, economic impact, and equity. Compared to voluntary policies, mandatory shelter-in-place policies were associated with a 3- to 5-fold lower population-adjusted mortality in the U.S. model and between 11- to 12-fold lower in the European one. Voluntary shelter-in-place measures were associated with overall increased mortality cost, as measured by value of a statistical life; somewhat greater decreases in gross domestic product; and substantial negative impacts on minority communities, who experienced markedly increased mortality rates (the percentage of minority deaths was 2.3 and 4 times greater in the U.S. model and 14.5 times higher in the European one) and mortality cost (2.7- and 4.5-fold higher in the U.S. model and 11.1-fold higher in the European one). We conclude that voluntary policies are less effective than mandatory ones, based on historical precedent and the current analysis. Negative effects on health equity mirrored the increased mortality outcomes of voluntary policies, and there was no apparent economic benefit associated with voluntary measures.

通过比较两个可比的欧洲国家和美国三个州的强制性和自愿非药物干预措施,分析了公共卫生措施对2019冠状病毒大流行的影响。采用生态回顾性队列研究设计,我们检验了死亡率、经济影响和公平性的差异。与自愿政策相比,在美国模型中,强制性安置政策与人口调整死亡率降低了3至5倍有关,在欧洲模型中,这一比例降低了11至12倍。按统计寿命值衡量,自愿安置措施与总体死亡成本增加有关;国内生产总值(gdp)降幅略大;以及对少数民族社区的重大负面影响,这些社区的死亡率(少数民族死亡率在美国模型中是2.3倍和4倍,在欧洲模型中是14.5倍)和死亡率成本(在美国模型中是2.7倍和4.5倍,在欧洲模型中是11.1倍)显著增加。根据历史先例和目前的分析,我们得出结论,自愿政策不如强制性政策有效。对卫生公平的负面影响反映了自愿政策导致死亡率增加的结果,而且与自愿措施没有明显的经济效益。
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引用次数: 1
The Future of Work in America: Demise of Employer-Sponsored Insurance and What Should Replace it. 美国工作的未来:雇主赞助的保险的消亡和取而代之的应该是什么。
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2021-10-20 DOI: 10.1177/00207314211044002
John Geyman

The COVID-19 pandemic has wrought fundamental changes in the US workplace, placing employer-sponsored health insurance (ESI) in disarray. Before the pandemic, ESI was the single largest share of private health insurance in the country, including some 150 million Americans. Even before the pandemic, however, ESI had become increasingly volatile and more unaffordable for both employers and employees. During the pandemic, many workers found that they could work at home remotely. Job losses during the pandemic left many millions uninsured, with many jobs lost indefinitely. Today, many Americans are rethinking how and where they want to be involved in the workplace, while many businesses are considering a future when more people are working from home or being replaced by robots, placing ESI in further jeopardy. This article brings historical perspective to these problems, showing how the private health insurance industry has failed the public interest by being too fragmented and unreliable to be afforded or depended upon. Three major reform alternatives are described, only 1 of which-single-payer improved Medicare for All-can provide stable universal coverage that meets the needs of all Americans while being affordable for patients, families, and taxpayers.

新冠肺炎大流行给美国的工作场所带来了根本性的变化,使雇主赞助的健康保险(ESI)陷入混乱。在大流行之前,ESI是该国私人医疗保险的最大份额,包括约1.5亿美国人。然而,即使在大流行之前,ESI也变得越来越不稳定,雇主和雇员都负担不起。在大流行期间,许多工人发现他们可以在家远程工作。大流行期间的失业导致数百万人没有保险,许多人无限期地失去了工作。今天,许多美国人正在重新思考他们希望如何以及在哪里参与工作场所,而许多企业正在考虑一个更多人在家工作或被机器人取代的未来,这将ESI置于进一步的危险之中。这篇文章从历史的角度来看待这些问题,展示了私人健康保险行业是如何因过于分散和不可靠而无法提供或依赖而辜负了公众利益的。报告描述了三种主要的改革方案,其中只有一种——单一付款人改进的全民医疗保险——可以提供稳定的全民覆盖,满足所有美国人的需求,同时为患者、家庭和纳税人负担得起。
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引用次数: 1
Spatial Analysis of the Sociodemographic Characteristics, Comorbidities, Hospitalization, Signs, and Symptoms Among Hospitalized Coronavirus Disease 2019 Cases in the State of Rio De Janeiro, Brazil. 巴西里约热内卢州2019年冠状病毒病住院病例的社会人口特征、合并症、住院、体征和症状的空间分析
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2021-10-07 DOI: 10.1177/00207314211044991
André T J Alves, Letícia M Raposo, Flávio F Nobre

After more than 1 year from the beginning of the pandemic, the coronavirus disease 2019 (COVID-19) has reached all continents. The number of infected people is still increasing, and Brazil is among the countries with the highest number of registered cases in the world. In this study, we investigated the profile of hospitalized COVID-19 cases and the eventual clusters of similar areas, using geographic information systems. The study was conducted using secondary data. Variables such as sociodemographic characteristics, comorbidities, hospitalization, signs, and symptoms among confirmed cases were considered for each microregion/city of the state of Rio de Janeiro. These proportions were used when calculating the Global Moran's I. The local indicator of spatial association was used to identify local clusters. A significant global spatial auto correlation was found in 28% of the variables. The presence of spatial autocorrelation indicates that the proportions of patients with COVID-19 according to these characteristics are spatially oriented. Moran maps reveal 2 clusters, 1 of high proportions and 1 of low proportions. Understanding the geographic patterns of COVID-19 may assist public health investigators, contributing to actions to prevent and control the pandemic in the state.

在大流行开始一年多后,2019年冠状病毒病(COVID-19)已传播到各大洲。受感染人数仍在增加,巴西是世界上登记病例最多的国家之一。在本研究中,我们使用地理信息系统调查了住院COVID-19病例的概况以及类似地区的最终聚集性。这项研究是使用二手数据进行的。考虑了里约热内卢州每个微区/城市确诊病例的社会人口特征、合并症、住院、体征和症状等变量。在计算全球Moran’s i时使用这些比例。空间关联的本地指标用于识别本地集群。28%的变量存在显著的全球空间自相关性。空间自相关的存在表明,根据这些特征的COVID-19患者比例具有空间方向性。Moran地图显示了两个集群,一个高比例,一个低比例。了解COVID-19的地理模式可以帮助公共卫生调查人员,有助于采取行动预防和控制该州的大流行。
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引用次数: 1
Impacts of Absolute and Relative Income on Self-Rated Health in Urban and Rural China. 绝对收入和相对收入对中国城乡居民自评健康的影响
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2020-05-03 DOI: 10.1177/0020731420922689
Jiaoli Cai, Audrey Laporte, Li Zhang, Yulin Zhao, Di Tang, Hongli Fan, Liqian Deng, Peter C Coyte

This study aims to assess the impacts of absolute and relative income on self-rated health (SRH) of residents in rural and urban China. Data were derived from the China Health and Nutrition Survey. Three distinct measures of relative income were considered (Gini coefficient, Yitzhaki index, and Deaton index) and computed for 3 geographic units (nation, province, and community). Nonlinear dynamic models for panel data were employed to test the absolute and relative income hypotheses. Absolute income was significantly associated with SRH among urban and rural populations. Relative income, as measured by the Gini coefficient, the Yitzhaki index, and the Deaton index, had statistically significant and negative impacts on SRH among the rural population, regardless of the reference group. For the urban population, the Gini coefficient was associated with SRH regardless of the reference group. In contrast, only the Yitzhaki index and the Deaton index at the provincial level were associated with SRH among the urban population. Our findings may provide a reference for policymakers to implement health policies designed to improve population health.

本研究旨在探讨绝对收入和相对收入对中国城乡居民自评健康(SRH)的影响。数据来源于中国健康与营养调查。考虑了三个不同的相对收入衡量标准(基尼系数、伊扎克指数和迪顿指数),并对3个地理单位(国家、省和社区)进行了计算。采用面板数据的非线性动态模型对绝对收入假设和相对收入假设进行检验。在城市和农村人口中,绝对收入与性健康和生殖健康显著相关。以基尼系数、伊扎克指数和迪顿指数衡量的相对收入对农村人口的生殖健康有统计学上显著的负面影响,无论参照组如何。对于城市人口,无论参照组如何,基尼系数都与SRH相关。相比之下,只有省级的Yitzhaki指数和Deaton指数与城市人口的生殖健康有关。本研究结果可为决策者实施旨在改善人口健康的卫生政策提供参考。
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引用次数: 3
Socioeconomic Inequalities in Small-for-Gestational-Age Births Before and During the Economic Crisis: An Ecologic Study of Trends in 13 Spanish Cities. 经济危机前后小胎龄儿的社会经济不平等:对13个西班牙城市趋势的生态学研究。
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2020-05-14 DOI: 10.1177/0020731420923532
María Felícitas Domínguez-Berjón, Glòria Pérez, Mercè Gotsens, Ricard Gènova, Unai Martín, Miguel Ruiz-Ramos

Economic recessions can increase socioeconomic inequalities in health. The objective of this study was to analyze socioeconomic inequalities in small-for-gestational-age (SGA) births before and during the Spanish economic crisis. We conducted an ecological study of trends based on 2 periods before the crisis (1999-2003 and 2004-2008) and another during the crisis (2009-2013). The study population was Spanish women resident in 13 cities who had given birth during 1999-2013. The prevalence of SGA was calculated for each census tract. A hierarchical Bayesian model was used to obtain the prevalence ratio (PR) and 95% credible intervals (CI). We analyzed the association between SGA and socioeconomic deprivation in each period for each city and for 3 age groups. The PR was above 1 and statistically significant for all 3 time periods in most of the 13 cities. The differences in PR between periods were only statistically significant for Madrid (PR = 1.56, 95% CI 1.48-1.65 for 1999-2003; PR = 1.28, 95% CI 1.19-1.38 for 2004-2008) and Barcelona (PR = 0.99, 95% CI 0.87-1.12 for 2004-2008; PR = 1.20, 95% CI 1.05-1.36 for 2009-2013). Socioeconomic inequalities in SGA births in small areas (census tracts) of most Spanish cities studied remained stable before and during the economic crisis.

经济衰退会加剧健康方面的社会经济不平等。本研究的目的是分析西班牙经济危机之前和期间小胎龄(SGA)出生的社会经济不平等。我们对危机前两个时期(1999-2003年和2004-2008年)和危机期间(2009-2013年)的趋势进行了生态学研究。研究对象是1999年至2013年期间在13个城市生育的西班牙女性。计算每个人口普查区的SGA患病率。采用层次贝叶斯模型获得患病率(PR)和95%可信区间(CI)。我们分析了每个城市和3个年龄组在每个时期的SGA与社会经济剥夺之间的关系。在13个城市中,大部分城市的3个时间段的PR都在1以上,且具有统计学意义。不同时期的PR差异仅在马德里有统计学意义(1999-2003年PR = 1.56, 95% CI 1.48-1.65;2004-2008年PR = 1.28, 95% CI 1.19-1.38)和巴塞罗那(2004-2008年PR = 0.99, 95% CI 0.87-1.12;2009-2013年PR = 1.20, 95% CI 1.05-1.36)。在经济危机之前和危机期间,大多数西班牙城市小地区(人口普查区)的SGA出生的社会经济不平等保持稳定。
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引用次数: 1
Determinants of Legislation on Social Health Insurance in Transition Countries. 转型期国家社会健康保险立法的决定因素。
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2020-08-20 DOI: 10.1177/0020731420952013
Sungkyoung Choi, Myongsei Sohn, Hyoung-Sun Jeong, Soyoon Kim

This study aims to address the question: Why did transition countries enact laws related to social health insurance (SHI) at different times, even though they experienced dissolution of the Soviet Union at the same time in the early 1990s? We used Ragin's fuzzy-set qualitative comparative analysis to investigate the configurations of causal conditions that affected the speed of developing SHI-related legislation in 24 post-socialist countries. The potential causal conditions were health status, economic status, level of governance, level of democracy, issue salience, and number of medical professionals. We found 3 pathways that led to the enactment of SHI-related laws and 1 pathway that inhibits enactment. The key factors impacting enactment of SHI-related laws were non-corrupt governments and realization of democracy. In addition, medical professionals' involvement in policymaking could be the factor to enact SHI-related laws. Further research is needed for more in-depth analysis regarding what the laws specifically include, type of health insurance systems that were adopted based on the laws, and if the legislation contributed toward achieving universal health coverage.

本研究旨在解决这样一个问题:为什么转型期国家在不同的时间颁布了与社会健康保险(SHI)相关的法律,尽管它们在20世纪90年代初同时经历了苏联的解体?我们使用Ragin的模糊集定性比较分析,调查了24个后社会主义国家中影响社会卫生相关立法发展速度的因果条件的配置。潜在的因果条件是健康状况、经济状况、治理水平、民主水平、问题突出程度和医疗专业人员数量。我们发现了3条导致shii相关法律制定的途径和1条抑制制定的途径。影响shii相关法律制定的关键因素是政府廉洁和民主的实现。此外,医疗专业人员参与政策制定可能是制定卫生相关法律的因素。需要进一步研究,以更深入地分析法律具体包括什么,根据法律采用的健康保险制度类型,以及立法是否有助于实现全民健康覆盖。
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引用次数: 2
Health Disparities Among Workers With Standing Position and Limited Restroom Access: A Cosmetics Saleswomen Study in South Korea. 站着工作和洗手间有限的员工之间的健康差异:韩国化妆品销售女性的研究。
IF 3.4 4区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2021-06-24 DOI: 10.1177/00207314211025490
Bokyoung Choi, Ji-Hwan Kim, Jaehong Yoon, Hyemin Lee, Seung-Sup Kim

Korean cosmetics sales workers in department stores face harmful working environments, including limited restroom access, working long hours in a standing position, and customer violence. This study investigated health disparities between cosmetics saleswomen and the general population of working women in South Korea. We assessed the prevalence of health indicators, including physician-diagnosed disease, using a cross-sectional survey of 860 Korean cosmetics saleswomen in September 2018. Health indicators of cosmetics saleswomen were compared to those of general working women from the nationally representative datasets (e.g., National Health Insurance Service-National Sample Cohort). We estimated age-standardized prevalence ratios (SPRs) for health outcomes, including physical, mental, and health-related behavioral conditions. Cosmetics saleswomen were more likely to be diagnosed or treated for physical and mental conditions (e.g., cystitis SPR: 4.03, 95% confidence interval [CI]: 3.48-4.65; plantar fasciitis SPR: 23.48, 95% CI: 18.12-29.93; varicose vein SPR: 38.41, 95% CI: 32.18-45.49; and depression SPR: 11.18, 95% CI: 8.53-14.40) compared to general working women. Prevalence of smoking and hazardous alcohol consumption was also higher among cosmetics saleswomen than those of general women workers. Given our findings, further research is needed to identify work-related risk factors that could deteriorate cosmetic sales workers' health in South Korea.

百货店化妆品销售人员的工作环境恶劣,卫生间使用受限,长时间站着工作,顾客暴力等。本研究调查了韩国化妆品销售女性和普通职业女性之间的健康差异。我们在2018年9月对860名韩国化妆品销售女性进行了横断面调查,评估了健康指标的流行程度,包括医生诊断的疾病。将化妆品女销售人员的健康指标与来自全国代表性数据集(例如,国家健康保险服务-国家样本队列)的普通职业妇女的健康指标进行比较。我们估计了健康结果的年龄标准化患病率(SPRs),包括身体、精神和与健康相关的行为状况。化妆品销售女性更有可能被诊断或治疗身体和精神疾病(例如,膀胱炎SPR: 4.03, 95%可信区间[CI]: 3.48-4.65;足底筋膜炎SPR: 23.48, 95% CI: 18.12 ~ 29.93;静脉曲张SPR: 38.41, 95% CI: 32.18-45.49;与一般职业女性相比,抑郁症SPR: 11.18, 95% CI: 8.53-14.40)。化妆品女销售员吸烟和有害酒精消费的流行率也高于一般女工。鉴于我们的研究结果,需要进一步的研究来确定与工作相关的风险因素,这些因素可能会损害韩国化妆品销售人员的健康。
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引用次数: 3
期刊
International Journal of Health Services
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