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Current Opinion in Otolaryngology & Head and Neck Surgery最新文献

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Management of traumatic auricular avulsion injury - partial and complete. 外伤性耳廓撕脱伤的处理-部分和完全。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-01 Epub Date: 2025-05-02 DOI: 10.1097/MOO.0000000000001054
Allison Goldberg, Rhorie Kerr

Purpose of review: Auricular avulsion injuries present complex reconstructive challenges due to the intricate three-dimensional (3D) structure and vascular supply of the ear. This review examines traditional and emerging techniques in auricular trauma repair, including microsurgical advancements, digital planning, tissue engineering, and 3D bioprinting, highlighting their impact on reconstructive outcomes.

Recent findings: Traditional techniques, such as multilayer closure and microsurgical reattachment, remain foundational in auricular reconstruction. However, recent studies suggest that subtotal amputations with small vascular pedicles may survive without microvascular anastomosis. Microsurgical refinements, including digital planning and customized surgical guides, enhance precision in reconstruction. Tissue engineering innovations, such as 3D bioprinting with biomimetic scaffolds and magnetoresponsive hydrogels, show promise for auricular cartilage regeneration. Additionally, postoperative adjuncts like antipressure alarm systems and bioactive hydrogels seeded with stem cells improve healing and long-term outcomes.

Summary: Auricular trauma repair is evolving through a combination of established and innovative techniques. Digital planning, microsurgical advancements, and tissue engineering are shaping a new era of patient-specific reconstruction. Future research should focus on refining these technologies, evaluating long-term efficacy, and addressing economic feasibility to optimize patient outcomes.

综述目的:由于耳部复杂的三维结构和血管供应,耳部撕脱伤的重建面临复杂的挑战。本文综述了耳部创伤修复的传统技术和新兴技术,包括显微外科手术的进步、数字计划、组织工程和3D生物打印,并强调了它们对重建结果的影响。近年来的研究发现:传统技术,如多层封闭和显微外科再植,仍然是耳廓重建的基础。然而,最近的研究表明,小血管蒂的次全截肢可以在没有微血管吻合的情况下存活。显微外科技术的改进,包括数字化规划和定制手术指南,提高了重建的精度。组织工程方面的创新,如生物3D打印仿生支架和磁响应水凝胶,显示了耳软骨再生的前景。此外,术后辅助装置,如抗压报警系统和植入干细胞的生物活性水凝胶,可以改善愈合和长期疗效。摘要:耳廓创伤修复是通过既有技术和创新技术的结合而不断发展的。数字规划、显微外科手术的进步和组织工程正在塑造一个针对患者的重建的新时代。未来的研究应侧重于改进这些技术,评估长期疗效,并解决经济可行性,以优化患者的结果。
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引用次数: 0
Techniques for maxillomandibular fixation: old and new. 上颌下颌固定技术:新旧。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-01 Epub Date: 2025-04-01 DOI: 10.1097/MOO.0000000000001043
Sarah Rathnam Akkina, Scott Eric Bevans, Alan Wellington Johnson

Purpose of review: Maxillomandibular fixation (MMF) is essential for many surgeries on the bony middle and lower face. MMF techniques have multiplied in recent years, each with unique benefits and drawbacks. This review catalogs MMF trends and evidence for and against the most prevalent MMF methods.

Recent findings: Traditional Erich arch bars remain the most robust technique in establishing MMF, particularly for comminuted/complicated fractures. Drawbacks are increased operative time required, wire stick injuries, poor oral hygiene, and gingival trauma. Screw-based techniques save considerable time but cannot stabilize comminuted fractures as adequately and risk tooth root and nerve damage. Embrasure wires offer time and cost savings but are solely for intraoperative use and uncomplicated fractures. Similarly, dental occlusion ties provide the benefits of reduced time and wire sticks, with the added capability of postoperative use, but require adequate dentition and minimally displaced fractures. Recent studies show decreased use of wire-based techniques, with increased adoption of hybrid systems and dental occlusion ties.

Summary: MMF techniques each have unique advantages and weaknesses. Selection should depend on surgical goals, including the severity of fractures, the need to maintain occlusion postoperatively, application/removal time, safety, and patient comfort.

回顾目的:上颌骨下颌固定(MMF)在许多骨性中、下面部手术中是必不可少的。近年来,MMF技术成倍增长,每种技术都有其独特的优点和缺点。这篇综述列出了MMF的趋势以及支持和反对最流行的MMF方法的证据。最近的研究发现:传统的Erich弓棒仍然是建立MMF最可靠的技术,特别是对于粉碎性/复杂骨折。缺点是需要增加手术时间,钢丝棒损伤,口腔卫生差,牙龈创伤。螺钉技术节省了大量时间,但不能充分稳定粉碎性骨折,并有损伤牙根和神经的风险。Embrasure钢丝可节省时间和成本,但仅用于术中使用和非复杂骨折。类似地,牙咬合带提供了减少时间和金属丝棒的好处,并增加了术后使用的能力,但需要足够的牙列和最小位移的骨折。最近的研究表明,使用基于金属丝的技术减少,越来越多地采用混合系统和牙齿咬合带。摘要:MMF技术各有其独特的优点和缺点。选择应取决于手术目标,包括骨折的严重程度、术后维持咬合的需要、应用/取出时间、安全性和患者舒适度。
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引用次数: 0
Hyperbaric oxygen therapy for wounds of the face, head and neck. 高压氧治疗面部、头部及颈部伤口。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-01 Epub Date: 2025-05-02 DOI: 10.1097/MOO.0000000000001053
Peter W Kahng, Adeeb Derakhshan, Shekhar K Gadkaree

Purpose of review: Wounds within the face, head, and neck region can have devastating aesthetic, functional, and potentially fatal outcomes for patients and often require multimodality treatment. Here we discuss the role of hyperbaric oxygen for a variety of wounds within the head and neck region and the clinically associated outcomes.

Recent findings: Hyperbaric oxygen (HBO) treatment can be useful in the management of wounds and infections within the head and neck region. While there are few randomized controlled clinical trials evaluating the effectiveness of HBO therapy, there is a large amount of retrospective literature supporting its adjunctive role in the treatment of radiation associated head and neck wounds, compromised grafts and flaps, and necrotizing soft tissue infections. The most common treatment protocols are typically initiated at 2-2.4 atmosphere absolute (ATA) at 100% oxygen for 90 min for 30 daily sessions, though this varies significantly in the available literature. In the setting of osteoradionecrosis (ORN) and medication-induced osteonecrosis of the jaw (MRONJ), however, emerging treatments such as the Potentiation by Clodronate (PENTOCLO) protocol may provide more effective treatment that HBO therapy.

Summary: Hyperbaric oxygen therapy should be considered as an adjuvant therapy for head and neck wounds involving radiated soft tissue, compromised local and free flaps, filler-induced soft tissue necrosis or blindness, and for necrotizing soft tissue infection; however, more randomized controlled trials are needed to better evaluate both their clinical impact as well as better establish treatment protocols, particularly in the setting of ORN and MRONJ.

综述目的:面部、头部和颈部的伤口对患者的审美、功能和潜在的致命后果具有破坏性,通常需要多种方式的治疗。在这里,我们讨论高压氧在头颈部各种伤口中的作用和临床相关的结果。最近的发现:高压氧(HBO)治疗可用于治疗头颈部的伤口和感染。虽然很少有随机对照临床试验评估HBO治疗的有效性,但有大量回顾性文献支持其在放疗相关头颈部伤口、移植物和皮瓣受损以及坏死性软组织感染的辅助治疗中的作用。最常见的治疗方案通常是在2-2.4大气压(ATA)下,在100%氧气下进行90分钟,每天30次,尽管在现有文献中差异很大。然而,在放射性骨坏死(ORN)和药物性颌骨骨坏死(MRONJ)的情况下,氯膦酸盐增强(PENTOCLO)方案等新兴治疗方法可能提供比HBO治疗更有效的治疗。总结:高压氧治疗应被视为头颈部创伤的辅助治疗,包括放射性软组织、局部和游离皮瓣受损、填充物引起的软组织坏死或失明,以及坏死性软组织感染;然而,需要更多的随机对照试验来更好地评估它们的临床影响,并更好地建立治疗方案,特别是在ORN和MRONJ的情况下。
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引用次数: 0
Factors associated with plate fractures in mandibular reconstruction. 下颌骨重建术中钢板骨折的相关因素。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-01 Epub Date: 2025-06-05 DOI: 10.1097/MOO.0000000000001065
George A Petrides, Richard J Fox, Ryan Winters

Purpose of review: Mandibular plate fracture (MPF) is a serious complication of mandibular reconstruction, leading to postoperative morbidity and potential revision surgeries. Recently, there has been an increased utilization of virtual surgical planning (VSP) with patient-specific reconstruction plates to decrease operative time and improve postoperative outcomes. It is critical for surgeons performing mandibular reconstruction to have a comprehensive understanding of the contributing factors and strategies for minimizing the likelihood of MPF.

Recent findings: This review examines the patient-related and surgical factors contributing to MPF. The literature highlights that patient-related factors include younger age and degree of occlusion, while surgical factors include lateral mandibular defects, the absence of coronoidectomy, and the use of bridging plates without bony reconstruction. Notably, recent studies suggest a reduction in MPFs with the implementation of VSP and patient-specific reconstruction plates.

Summary: This review aims to inform surgeons about patients who are at increased risk of MPF following mandibular reconstruction, emphasizing the need for close monitoring. Furthermore, it underscores the additional benefits of VSP and patient-specific reconstruction plates in improving postoperative outcomes. However, further research is required to assess the long-term efficacy of these reconstruction plates.

回顾目的:下颌钢板骨折(MPF)是下颌重建的严重并发症,导致术后发病率和潜在的翻修手术。最近,虚拟手术计划(VSP)与患者特异性重建钢板的使用越来越多,以减少手术时间并改善术后预后。对于进行下颌骨重建的外科医生来说,全面了解导致MPF发生的因素和策略是至关重要的。最近的发现:本综述探讨了患者相关因素和手术因素对MPF的影响。文献强调,患者相关因素包括年龄较小和咬合程度,而手术因素包括下颌外侧缺损、未切除冠状体和使用桥接板而未进行骨重建。值得注意的是,最近的研究表明,实施VSP和患者特异性重建钢板可以减少mpf。摘要:本综述旨在告知外科医生下颌骨重建后MPF风险增加的患者,强调密切监测的必要性。此外,它强调了VSP和患者特异性重建钢板在改善术后预后方面的额外益处。然而,需要进一步的研究来评估这些重建钢板的长期疗效。
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引用次数: 0
Surface scanning and imaging in craniofacial surgery. 颅面外科的表面扫描与成像。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-08-01 Epub Date: 2025-06-12 DOI: 10.1097/MOO.0000000000001062
Estelle Viaud-Murat, Dhruv Patel, Sherard A Tatum

Purpose of review: This review describes recent innovations in craniofacial imaging, focusing on emerging techniques such as 3D photogrammetry, smartphone-based scanning, and artificial intelligence applied to cephalometric assessments in facial plastic and reconstructive surgery.

Recent findings: Traditional methods like occipitofrontal circumference and cephalic index remain widely used, but newer, more precise technologies have recently emerged. 3D photogrammetry is a reproducible, safe, and noninvasive alternative, offering detailed cranial modeling using external landmarks. The integration of smartphone technologies has further democratized craniofacial imaging by enabling accurate 3D scans with minimal cost and radiation exposure. Despite variability in certain facial regions, these technologies have shown promising accuracy for clinical use. Furthermore, AI-driven approaches enhance diagnostic precision by generating synthetic data and improving landmark detection in complex cranial morphologies.

Summary: Recent technological advances are reshaping craniofacial imaging and optimizing preoperative and postoperative care in facial plastic and reconstructive surgery. 3D imaging and AI applications offer significant improvements over traditional methods and allow for more precise and reliable methods for operative planning and longitudinal assessments. As these tools develop, they are bound to become the new standards for clinical evaluation of craniofacial anomalies.

综述目的:本综述描述了颅面成像的最新创新,重点介绍了新兴技术,如3D摄影测量、基于智能手机的扫描和人工智能应用于面部整形和重建手术的颅面测量评估。最新发现:枕额围和头侧指数等传统方法仍被广泛使用,但最近出现了更新、更精确的技术。3D摄影测量是一种可重复、安全、无创的替代方法,使用外部地标提供详细的颅骨建模。智能手机技术的集成进一步普及了颅面成像,使精确的3D扫描以最小的成本和辐射暴露成为可能。尽管某些面部区域存在差异,但这些技术在临床应用中显示出了良好的准确性。此外,人工智能驱动的方法通过生成合成数据和改进复杂颅形态的地标检测来提高诊断精度。摘要:最近的技术进步正在重塑颅面成像,优化面部整形和重建手术的术前和术后护理。3D成像和人工智能应用对传统方法进行了重大改进,并为作业计划和纵向评估提供了更精确、更可靠的方法。随着这些工具的发展,它们必将成为颅面畸形临床评价的新标准。
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引用次数: 0
Non-obstructive sleep apnea pediatric sleep disorders: what the otolaryngologist should know. 非阻塞性睡眠呼吸暂停儿童睡眠障碍:耳鼻喉科医生应该知道什么。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-07-03 DOI: 10.1097/MOO.0000000000001066
Rachel L Whelan, Cristina M Baldassari

Purpose of review: Sleep complaints are exceedingly common in children and are associated with cognitive and psychosocial impairment. Obstructive sleep apnea (OSA) accounts for only a small percentage of pediatric sleep problems. A comprehensive understanding of nonbreathing-related sleep disorders in pediatric patients is, therefore, needed to adequately assess and treat pediatric patients presenting with sleep concerns.

Recent findings: The review below summarizes the most common non-OSA sleep disorders in pediatric patients, focusing on comprehensive evaluation and evidence-based treatment recommendations. We also describe and review the literature on the newest pediatric sleep disorder, restless sleep disorder (RSD).

Summary: Pediatric otolaryngologists should be equipped to take a concise yet thorough sleep history, identify features of non-OSA sleep disorders, counsel patients and families regarding key sleep hygiene measures, and appropriately refer patients with suspected non-OSA sleep disorders such as circadian rhythm disorders, parasomnias, and/or narcolepsy for additional sleep medicine evaluation, testing and/or treatment whenever indicated.

回顾目的:睡眠抱怨在儿童中非常常见,并与认知和心理障碍有关。阻塞性睡眠呼吸暂停(OSA)只占儿科睡眠问题的一小部分。因此,需要全面了解儿科患者的非呼吸相关睡眠障碍,以充分评估和治疗出现睡眠问题的儿科患者。最新发现:以下综述总结了儿科患者中最常见的非阻塞性睡眠障碍,重点是综合评估和循证治疗建议。我们还介绍和回顾了最新的儿童睡眠障碍,不宁睡眠障碍(RSD)的文献。总结:儿科耳鼻喉科医生应具备简明而全面的睡眠病史,识别非阻塞性睡眠呼吸暂停睡眠障碍的特征,就关键的睡眠卫生措施向患者和家属提供咨询,并适当地转诊疑似非阻塞性睡眠呼吸暂停睡眠障碍的患者,如昼夜节律障碍、睡眠异常和/或发作性睡病,进行额外的睡眠药物评估、测试和/或治疗。
{"title":"Non-obstructive sleep apnea pediatric sleep disorders: what the otolaryngologist should know.","authors":"Rachel L Whelan, Cristina M Baldassari","doi":"10.1097/MOO.0000000000001066","DOIUrl":"https://doi.org/10.1097/MOO.0000000000001066","url":null,"abstract":"<p><strong>Purpose of review: </strong>Sleep complaints are exceedingly common in children and are associated with cognitive and psychosocial impairment. Obstructive sleep apnea (OSA) accounts for only a small percentage of pediatric sleep problems. A comprehensive understanding of nonbreathing-related sleep disorders in pediatric patients is, therefore, needed to adequately assess and treat pediatric patients presenting with sleep concerns.</p><p><strong>Recent findings: </strong>The review below summarizes the most common non-OSA sleep disorders in pediatric patients, focusing on comprehensive evaluation and evidence-based treatment recommendations. We also describe and review the literature on the newest pediatric sleep disorder, restless sleep disorder (RSD).</p><p><strong>Summary: </strong>Pediatric otolaryngologists should be equipped to take a concise yet thorough sleep history, identify features of non-OSA sleep disorders, counsel patients and families regarding key sleep hygiene measures, and appropriately refer patients with suspected non-OSA sleep disorders such as circadian rhythm disorders, parasomnias, and/or narcolepsy for additional sleep medicine evaluation, testing and/or treatment whenever indicated.</p>","PeriodicalId":55195,"journal":{"name":"Current Opinion in Otolaryngology & Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing laryngology through artificial intelligence: a comprehensive review of implementation frameworks and strategies. 通过人工智能推动喉科学发展:实施框架和战略综合评述。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-06-01 Epub Date: 2025-03-03 DOI: 10.1097/MOO.0000000000001041
Rachel B Kutler, Linh He, Ross W Green, Anaïs Rameau

Purpose of review: This review aims to explore the integration of artificial intelligence (AI) in laryngology, with specific focus on the barriers preventing translation from pilot studies into routine clinical practice and strategies for successful implementation.

Recent findings: Laryngology has seen an increasing number of pilot and proof-of-concept studies demonstrating AI's ability to enhance diagnostics, treatment planning, and patient outcomes. Despite these advancements, few tools have been successfully adopted in clinical settings. Effective implementation requires the application of established implementation science frameworks early in the design phase. Additional factors required for the successful integration of AI applications include addressing specific clinical needs, fostering diverse and interdisciplinary teams, and ensuring scalability without compromising model performance. Governance, epistemic, and ethical considerations must also be continuously incorporated throughout the project lifecycle to ensure the safe, responsible, and equitable use of AI technologies.

Summary: While AI hold significant promise for advancing laryngology, its implementation in clinical practice remains limited. Achieving meaningful integration will require a shift toward practical solutions that prioritize clinicians' and patients' needs, usability, sustainability, and alignment with clinical workflows.

综述目的:本综述旨在探讨人工智能(AI)在喉科的整合,特别关注从初步研究转化为常规临床实践的障碍和成功实施的策略。最近的发现:喉科已经看到越来越多的试点和概念验证研究,证明人工智能能够增强诊断、治疗计划和患者预后。尽管取得了这些进步,但在临床环境中成功采用的工具很少。有效的实现需要在设计阶段早期应用已建立的实现科学框架。成功集成人工智能应用程序所需的其他因素包括满足特定的临床需求,培养多样化和跨学科团队,以及在不影响模型性能的情况下确保可扩展性。治理、认知和伦理考虑也必须在整个项目生命周期中持续纳入,以确保人工智能技术的安全、负责和公平使用。摘要:虽然人工智能在推进喉科学方面具有重要的前景,但其在临床实践中的应用仍然有限。实现有意义的整合需要转向实用的解决方案,优先考虑临床医生和患者的需求、可用性、可持续性,并与临床工作流程保持一致。
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引用次数: 0
Editorial introductions. 编辑介绍。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-06-01 Epub Date: 2025-04-30 DOI: 10.1097/MOO.0000000000001050
{"title":"Editorial introductions.","authors":"","doi":"10.1097/MOO.0000000000001050","DOIUrl":"https://doi.org/10.1097/MOO.0000000000001050","url":null,"abstract":"","PeriodicalId":55195,"journal":{"name":"Current Opinion in Otolaryngology & Head and Neck Surgery","volume":"33 3","pages":"v-vi"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rhinology in the developing world - an important yet frequently overlooked theme. 发展中国家的鼻科学——一个重要但经常被忽视的主题。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-06-01 Epub Date: 2025-04-02 DOI: 10.1097/MOO.0000000000001047
Emma Stapleton
{"title":"Rhinology in the developing world - an important yet frequently overlooked theme.","authors":"Emma Stapleton","doi":"10.1097/MOO.0000000000001047","DOIUrl":"10.1097/MOO.0000000000001047","url":null,"abstract":"","PeriodicalId":55195,"journal":{"name":"Current Opinion in Otolaryngology & Head and Neck Surgery","volume":" ","pages":"162-163"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Granulomatous disorders of the nose and paranasal sinuses: perspective from low- and middle-income countries. 鼻和鼻窦肉芽肿性疾病:来自低收入和中等收入国家的观点。
IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY Pub Date : 2025-06-01 Epub Date: 2025-04-02 DOI: 10.1097/MOO.0000000000001048
Baskaran Ranganathan, Kiran Natarajan, Raghu Nandhan, Amr Abdlehamid

Purpose of review: This is a comprehensive overview of current trends in the prevalence, clinical presentation, diagnostic challenges and management of granulomatous disorders involving the nose and paranasal sinuses in low- and middle-income countries. Emphasis is placed on infective aetiologies contributing to granulomatous diseases and the emerging innovations in the diagnosis and management of these conditions.

Recent findings: Granulomatous inflammations represent a distinctive spectrum of conditions arising from infectious, autoimmune, neoplastic, and chemical exposures. The prevalence of these disorders varies globally, with infectious aetiologies being more common in subtropical regions and autoimmune inflammatory conditions predominating in Western countries. Notably, the global burden of certain infectious granulomatous diseases is declining due to improved awareness, socio-economic conditions, and enhanced access to healthcare.However, the incidence of invasive fungal mucormycosis has risen sharply following the COVID-19 pandemic, particularly in the Indian subcontinent. Contributing factors include diabetes mellitus, excessive use of high-dose corticosteroids, and environmental influences. Early diagnosis, along with aggressive surgical debridement and antifungal therapy, remains critical for successful management.

Summary: Otolaryngologists must be aware of granulomatous conditions affecting the nose and paranasal sinuses, given their potential to cause significant morbidity if left untreated. Timely diagnosis relies on clinical suspicion supported by blood tests, imaging, and histopathology for effective intervention.

综述的目的:这是对低收入和中等收入国家涉及鼻子和鼻窦的肉芽肿性疾病的流行、临床表现、诊断挑战和管理的当前趋势的全面概述。重点放在感染性病原学有助于肉芽肿性疾病和新兴的创新诊断和管理这些条件。最近发现:肉芽肿性炎症是由感染性、自身免疫性、肿瘤性和化学物质暴露引起的一种独特的疾病。这些疾病的患病率在全球范围内各不相同,感染性病因在亚热带地区更为常见,自身免疫性炎症在西方国家占主导地位。值得注意的是,由于认识的提高、社会经济条件的改善和获得保健的机会的增加,某些传染性肉芽肿疾病的全球负担正在下降。然而,在2019冠状病毒病大流行之后,侵袭性真菌毛霉病的发病率急剧上升,特别是在印度次大陆。诱发因素包括糖尿病、过度使用大剂量皮质类固醇和环境影响。早期诊断,以及积极的手术清创和抗真菌治疗,仍然是成功治疗的关键。摘要:耳鼻喉科医生必须意识到影响鼻子和副鼻窦的肉芽肿状况,因为如果不及时治疗,它们有可能导致严重的发病率。及时诊断依赖于血液检查、影像学和组织病理学支持的临床怀疑,以进行有效的干预。
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引用次数: 0
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Current Opinion in Otolaryngology & Head and Neck Surgery
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