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Deep Learning-Based Magnetic Resonance-Ultrashort Time of Echo Imaging for Analyzing Degeneration of Intervertebral Disc Cartilage Endplate and Rehabilitation Nursing 基于深度学习的磁共振-超短时间回波成像分析椎间盘软骨终板退变及康复护理
IF 0.4 4区 化学 Q4 CHEMISTRY, PHYSICAL Pub Date : 2022-07-13 DOI: 10.1155/2022/8709075
Sainan Jiang, Xiaoyun Song, Chengming Jiang

This study was focused on the magnetic resonance-ultrashort time of echo (MR-UTE) imaging technology based on the convolution residual network (CRN) algorithm to evaluate the degeneration of intervertebral disc endplate (DIDCE) and the efficacy of rehabilitation nursing intervention. In this study, 90 patients with intervertebral disc degeneration in the hospital were randomly divided into an intervention group (45 cases) and a control group (45 cases). All patients were scanned by a magnetic resonance imaging system, and the original UTE images were postprocessed. The control group received routine nursing. The intervention group used massage and rehabilitation nursing intervention measures. The CRN algorithm is used to reconstruct the undersampled MR image and compared with ESPIRiT algorithm and the Regridding algorithm. The result found that CRN has more advantages than ESPIRiT and Regridding reconstruction algorithms. The proportion of partial disappearance and complete disappearance of fibrous ring structure in the low back pain group was higher than that in the non-low back pain group, with a statistical difference (P < 0.05). 90 patients with intervertebral disc cartilage endplate degeneration were divided into lumbago group (62 cases) and nonlumbago group (28 cases) according to whether they had lumbago. The nursing satisfaction of patients in the intervention group (97%) is significantly higher than that of patients in the control group (69%) (P < 0.05). In conclusion, the CRN algorithm successfully removes artifacts and noise in the undersampled image. Cartilage endplate, annulus fibrosus, and bony endplate partially disappeared by the MR-UTE imaging technique. Rehabilitation intervention proved to have a positive effect on the treatment of patients with intervertebral disc degeneration and can improve patients’ satisfaction.

本研究主要采用基于卷积残差网络(CRN)算法的磁共振-超短时间回波(MR-UTE)成像技术评价椎间盘终板退变(DIDCE)及康复护理干预的效果。本研究将90例住院的椎间盘退变患者随机分为干预组(45例)和对照组(45例)。所有患者均接受磁共振成像系统扫描,并对原始UTE图像进行后处理。对照组患者给予常规护理。干预组采用按摩、康复护理等干预措施。利用CRN算法对欠采样的MR图像进行重构,并与ESPIRiT算法和Regridding算法进行比较。结果表明,CRN重构算法比spirit和Regridding重构算法更有优势。腰痛组纤维环结构部分消失和完全消失的比例高于非腰痛组,差异有统计学意义(P <;0.05)。将90例椎间盘软骨终板退变患者根据是否有腰痛分为腰痛组(62例)和非腰痛组(28例)。干预组患者的护理满意度(97%)显著高于对照组(69%)(P <;0.05)。综上所述,CRN算法成功地去除了欠采样图像中的伪影和噪声。软骨终板、纤维环、骨终板部分消失。康复干预对椎间盘退变患者的治疗有积极的效果,可以提高患者的满意度。
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引用次数: 0
MRI Semi-Quantitative Evaluation of Clinical Features of Cartilage Injury in Patients with Osteoarthritis 骨关节炎软骨损伤临床特征的MRI半定量评价
IF 0.4 4区 化学 Q4 CHEMISTRY, PHYSICAL Pub Date : 2022-07-08 DOI: 10.1155/2022/9057181
Xianchao Zhou, Xiang Shen

This study aimed to investigate the correlation between magnetic resonance imaging (MRI) findings of articular cartilage and clinical symptoms in patients with osteoarthritis (OA). Eighty patients with OA were selected as the study subjects (OA group) and 80 healthy subjects during the same period were also selected as the control group. All subjects underwent knee sagittal PDW-SPAIR, sagittal T1WI-aTSE, sagittal T2WI-TSE, coronal PDW-SPAIR, sagittal 3D-WATSc, and sagittal T2 mapping scans. Thereafter, all subjects underwent clinical assessment. The whole-organ MRI score (WORMS) was adopted for MRI examination and semiquantitative analysis, and the T2 value was calculated. The correlation among T2 value, WORMS, and Western Ontario and Mc Master University OA Index (WOMAC) was then compared and analyzed. The correlation coefficients between T2 values and WORMS in each sub-region of patients with OA were 0.8, 0.55, −0.038, 0.811, and 0.743; the correlation coefficients between WORMS and WOAMC were 0.66, 0.71, 0.46, and 0.88; and the correlation coefficients between T2 values and WOAMC were 0.483, 0.33, 0.282, and 0.636, respectively. There was a significant positive correlation between the results of MRI semiquantitative analysis and clinical symptoms as well as disease severity in patients with OA.

本研究旨在探讨骨关节炎(OA)患者关节软骨的磁共振成像(MRI)表现与临床症状的相关性。选取80例OA患者作为研究对象(OA组),同时选取同期健康受试者80例作为对照组。所有受试者均接受膝关节矢状位PDW-SPAIR、矢状位T1WI-aTSE、矢状位T2WI-TSE、冠状位PDW-SPAIR、矢状位3D-WATSc和矢状位T2成像扫描。之后,所有受试者进行临床评估。采用全器官MRI评分(WORMS)进行MRI检查和半定量分析,计算T2值。比较分析T2值与WORMS、Western Ontario and Mc Master University OA Index (WOMAC)的相关性。OA患者各亚区T2值与WORMS的相关系数分别为0.8、0.55、- 0.038、0.811、0.743;WORMS与WOAMC的相关系数分别为0.66、0.71、0.46、0.88;T2值与WOAMC的相关系数分别为0.483、0.33、0.282、0.636。MRI半定量分析结果与OA患者的临床症状及病情严重程度呈显著正相关。
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引用次数: 0
Awakening Effect of Transcranial Magnetic Stimulation with Multimodal Magnetic Resonance Imaging under Three-Dimensional Reconstruction Algorithm Combined with Wake-Up Nursing on Patients with Massive Cerebral Infarction 三维重建算法下多模态磁共振经颅磁刺激结合唤醒护理对大面积脑梗死患者的唤醒效果
IF 0.4 4区 化学 Q4 CHEMISTRY, PHYSICAL Pub Date : 2022-07-06 DOI: 10.1155/2022/3495098
Bocan Chen, Li Li, Xiaoxia Ji

This study was aimed to provide arousal treatment for disturbance of consciousness in patients with massive cerebral infarction, using multimodal magnetic resonance imaging (MRI)-assisted transcranial magnetic stimulation (TMS) under three-dimensional reconstruction algorithm combined with wake-up nursing. The application effect was also evaluated. 80 patients with massive cerebral infarction were selected as the research objects. These patients were divided into the control group (routine nursing and TMS) and the experimental group (routine nursing, multisensory stimulation wake-up nursing, and TMS) according to the even- and odd-numbered admission orders. There were 40 cases in each group, and the treatment effects of the two groups were compared and analyzed. The peak signal-to-noise ratio (PSNR) (800 dB) of the bilateral filtering algorithm was higher than that of the wavelet threshold denoising (321 dB) and the nonlocal mean filtering algorithm (455 dB). The segmentation accuracy of the improved region growing method/fuzzy spatial clustering algorithm (96.21% and 97.22%) was higher than that of the unimproved ones (82.11% and 79.99%). The Glasgow Coma Scale (GCS), Coma Recovery Scale-Revised (CRS-R), and Dysfunction Scale (DFS) scores of the experimental group were significantly higher than those of the control group 1 week and 2 weeks after treatment (P < 0.05). The awakening rate of patients in the experimental group (95%) was also significantly higher than that in the control group (72.5%), and the time needed for waking up was (2.28 ± 2.92) hours, lower than that in the control group (4.34 ± 3.49) hours (P < 0.05). The three-dimensional reconstruction algorithm could effectively improve the display effect of MRI images and assist in the examination of diseases. Multisensory stimulation wake-up nursing combined with TMS could promote patients to wake up more quickly and help the recovery of brain function of patients in the treatment of massive cerebral infarction and disturbance of consciousness.

本研究旨在采用多模态磁共振成像(MRI)辅助经颅磁刺激(TMS)在三维重建算法下结合唤醒护理,对大面积脑梗死患者的意识障碍进行唤醒治疗。并对其应用效果进行了评价。选取80例大面积脑梗死患者作为研究对象。按双、奇数号入院顺序分为对照组(常规护理+经颅磁刺激)和实验组(常规护理+多感官刺激唤醒护理+经颅磁刺激)。两组各40例,比较分析两组治疗效果。双边滤波算法的峰值信噪比(PSNR)为800 dB,高于小波阈值去噪算法的峰值信噪比(321 dB)和非局部均值滤波算法的峰值信噪比(455 dB)。改进区域生长法和模糊空间聚类算法的分割准确率分别为96.21%和97.22%,高于未改进区域生长法和模糊空间聚类算法的分割准确率分别为82.11%和79.99%。治疗后1周和2周,实验组的格拉斯哥昏迷量表(GCS)、昏迷恢复量表-修订版(CRS-R)和功能障碍量表(DFS)评分均显著高于对照组()。实验组患者苏醒率(95%)也显著高于对照组(72.5%),苏醒所需时间(2.28±2.92)小时,低于对照组(4.34±3.49)小时()。三维重建算法可以有效提高MRI图像的显示效果,辅助疾病的检查。多感觉刺激唤醒护理联合经颅磁刺激可促进大面积脑梗死及意识障碍患者更快苏醒,有助于患者脑功能恢复。
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引用次数: 0
The Clebsch–Gordan Coefficients and Their Application to Magnetic Resonance Clebsch-Gordan系数及其在磁共振中的应用
IF 0.4 4区 化学 Q4 CHEMISTRY, PHYSICAL Pub Date : 2022-05-17 DOI: 10.1155/2022/1143341
Edward P. Saliba, Alexander B. Barnes

The Clebsch–Gordan coefficients are extremely useful in magnetic resonance theory, yet have an infamous perceived level of complexity by many students. The Clebsch–Gordan coefficients are used to determine both the matrix elements of the spherical tensor operators and the total angular momentum states of a system of component angular momenta. Full derivations of these coefficients are rarely worked through step by step. Instead, students are provided with tables accompanied by little or no explanation of where the values in it originated from. This lack of direction is often a source of confusion for students. For this reason, we work through two common examples of the application of the Clebsch–Gordan coefficients to magnetic resonance experiments. In the first, we determine the components of the magnetic resonance Hamiltonian of ranks 0, 1, and 2 and use these to identify the secular portion of the static, heteronuclear dipolar Hamiltonian. In the second, we derive the singlet and triplet states that arise from the interaction of two identical spin-1/2 particles.

Clebsch-Gordan系数在磁共振理论中是非常有用的,然而对于许多学生来说,它的复杂程度是臭名昭著的。Clebsch-Gordan系数用于确定球面张量算子的矩阵元素和分量角动量系统的总角动量状态。这些系数的完全推导很少是一步一步地完成的。相反,给学生提供的表格很少或根本没有解释其中的值是从哪里来的。这种方向的缺乏往往是学生困惑的根源。出于这个原因,我们通过两个常见的例子,应用克莱布希-戈登系数的磁共振实验。首先,我们确定了0、1和2阶的磁共振哈密顿量的分量,并用这些分量来确定静态异核偶极哈密顿量的长期部分。在第二部分,我们推导了由两个相同的自旋为1/2的粒子相互作用产生的单重态和三重态。
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引用次数: 0
Multispin Cross-Correlated Transverse Dipolar NMR Relaxation in Solution 溶液中的多自旋交叉相关横向偶极核磁共振弛豫
IF 0.4 4区 化学 Q4 CHEMISTRY, PHYSICAL Pub Date : 2022-04-12 DOI: 10.1155/2022/1617848
Erik R. P. Zuiderweg

In this paper, we want to consider what would be involved in calculating the R2 relaxation of amide protons in a protein caused by dipolar interactions with nearby protons, for which there are many. NMR textbooks give analytical equations and sometimes derivations for solution NMR relaxation due to dipolar interactions between two spins. There are also closed equations for dipolar interactions between three spins, which include relaxation interference, also known as cross-correlated cross-relaxation. We here derive an expression for interference between four spins. For larger systems, such as amide protons in a protein, we develop a local-field methodology, from which solution relaxation interference can be computed for a basically limitless number of interacting spins.

在本文中,我们想要考虑计算蛋白质中酰胺质子的R2弛豫所涉及的是由与附近质子的偶极相互作用引起的,这样的质子有很多。核磁共振课本给出了由于两个自旋之间的偶极相互作用而引起的溶液核磁共振弛豫的解析方程,有时也给出了推导。也有三个自旋之间的偶极相互作用的封闭方程,其中包括弛豫干扰,也称为交叉相关交叉弛豫。我们在这里导出了四个自旋之间干涉的表达式。对于更大的系统,如蛋白质中的酰胺质子,我们开发了一种局部场方法,从这种方法可以计算出基本上无限数量的相互作用自旋的溶液弛豫干扰。
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引用次数: 0
Groundwater Potential Assessment Using Vertical Electrical Sounding and Magnetic Methods: A Case of Adilo Catchment, South Nations, Nationalities and Peoples Regional Government, Ethiopia 利用垂直电测深和磁法评价地下水潜力:以阿迪洛流域为例,埃塞俄比亚南部国家、民族和人民地区政府
IF 0.4 4区 化学 Q4 CHEMISTRY, PHYSICAL Pub Date : 2021-12-08 DOI: 10.1155/2021/5424865
Mulugeta Markos, Abel Saka, Leta Tesfaye Jule, N. Nagaprasad, Krishnaraj Ramaswamy

Vertical electrical sounding and magnetic methods were carried out to assess groundwater potential in Adilo catchment, Kembata Tembaro Zone, South Nations, Nationalities and Peoples Regional Government, Main Ethiopian Rift. The data were acquired from eight VES points using Schlumberger electrode arrays with maximum half current electrode spacing (AB/2 = 500) and 253 magnetic data points were analyzed. The qualitative analysis of VES data was accomplished by using curves, apparent resistivity, and pseudodepths, and the quantitative interpretations of the VES data were constructed by the VES data using IPI-Res3, IPI2Win, and surfer software and constructing geoelectric section along with profiles and lithological information from the borehole and Geosoft interpretation was used for magnetic data. The VES results of the data revealed five geoelectric layers which differ in degree of fracturing, weathering, and formation. The upward continued magnetic field map anomaly to 560 m illustrated northwestern to the southwest; areas have a low magnetic anomaly. Examining the potential aquifer of profile one’s geoelectric section, the horizons of layer four were better potential aquifers as the highly fractured and weathered ignimbrite zone of layer five of VES13 was 219 m deeper than the depths of the other VES points, and along with profile two geoelectric sections, the horizon of layer four VES23 layer five has the lowest resistivity with large thickness at a depth of 253 m. Thus, the low resistivity and the large thickness of these formations are an indication of the high yield of groundwater potential in the study area.

采用垂直电测深和磁法评估了埃塞俄比亚主要裂谷南部国家、民族和人民地区政府Kembata Tembaro地区Adilo集水区的地下水潜力。使用最大半电流电极间距(AB/2 = 500)的斯伦贝谢电极阵列从8个VES点获取数据,并分析了253个磁数据点。利用测井曲线、视电阻率、拟深度等方法对VES数据进行定性分析,利用IPI-Res3、IPI2Win和surfer软件对VES数据进行定量解释,并结合钻孔剖面和岩性信息构建地电剖面,利用Geosoft软件对磁力数据进行解释。探测结果显示了5个地电层,这些地电层的压裂程度、风化程度和地层形成程度各不相同。560m的向上连续磁场图异常由西北向西南方向显示;该地区具有低磁异常。对1号剖面地电剖面的潜在含水层进行检测发现,VES13第5层高度断裂风化的火成岩带比其他测点深度深219 m,第4层为较好的潜在含水层,与2号剖面地电剖面一样,VES23第5层的层位在深度253 m处电阻率最低,厚度较大。因此,这些地层的低电阻率和大厚度表明研究区地下水潜力高。
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引用次数: 0
What Are the Relative Intensities of the Components of NMR Spectral Multiplets from Quadrupolar Nuclei in Uniformly Anisotropic Media? 均匀各向异性介质中四极核磁共振波谱多态各组分的相对强度是什么?
IF 0.4 4区 化学 Q4 CHEMISTRY, PHYSICAL Pub Date : 2021-02-19 DOI: 10.1155/2021/8890478
Stuart J. Elliott, Philip W. Kuchel

Stretched hydrogels make uniformly anisotropic environments for quadrupolar nuclei such as 2H, 23Na, and 133Cs. Such surroundings cause the partial alignment of nuclear spin bearing ions and molecules that is sufficiently pronounced to alter the nuclear magnetic resonance spectra of the guest species. In most cases, resonance splittings are directly related to the spin quantum number I. The relative intensities of the components of the resonance multiplets can be inferred from basic quantum mechanics.

拉伸后的水凝胶为四极核(如2H、23Na和133c)提供了均匀的各向异性环境。这样的环境导致核自旋离子和分子的部分排列,这足以改变客体物种的核磁共振光谱。在大多数情况下,共振分裂与自旋量子数i直接相关,共振多重态各分量的相对强度可以从基本量子力学中推断出来。
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引用次数: 0
A Statistical Robust Approach to Design Parallel Transmit Radiofrequency Excitations in MRI 磁共振成像中平行发射射频激励设计的统计鲁棒方法
IF 0.4 4区 化学 Q4 CHEMISTRY, PHYSICAL Pub Date : 2020-09-18 DOI: 10.1155/2020/6018107
Vincent Gras, Franck Mauconduit, Nicolas Boulant

In MRI, at ultrahigh field, the use of parallel transmit radiofrequency (RF) arrays is very beneficial to better control spin excitation spatially. In that framework, the so-called “universal pulse” technique, proposed recently for head imaging at 7 tesla, gives access to “plug-and-play” nonadiabatic solutions exhibiting good robustness against intersubject variations in the resonant transmit fields. This new type of solution has been defined so far as the result of numerical pulse optimizations performed across a collection of RF field maps acquired on a small population sample (pulse design database). In this work, we investigate an alternative universal pulse design approach in the linear small tip angle regime whereby the database of RF field maps is first transformed into a second-order statistical model and which then exploits a statistical robust design formalism for the optimization of the RF and magnetic field gradient waveforms. Experimental validation with an eightfold transmit RF coil for 7 tesla brain imaging shows that this new approach brings some benefit in terms of computational efficiency. Hence, for a design database composed of 35 maps, the computation time initially of 50 min could be reduced down to 3 min. The proposed statistical approach thus enables integration of large databases, presumably necessary to ensure robust solutions. Finally, it provides means to compute flip angle statistics and, along with it, simple performance metrics for quality assurance (RF pulse performance) or guidance in the optimization of TX array architectures.

在磁共振成像中,在超高场下,平行发射射频(RF)阵列的使用有利于更好地控制自旋激发的空间。在这个框架下,所谓的“通用脉冲”技术,最近被提出用于7特斯拉的头部成像,提供了“即插即用”的非绝热解决方案,在共振发射场的主体间变化中表现出良好的鲁棒性。到目前为止,这种新型解决方案已被定义为在小样本(脉冲设计数据库)上获得的射频场图集合上进行数值脉冲优化的结果。在这项工作中,我们研究了线性小尖端角区域的另一种通用脉冲设计方法,其中射频场图数据库首先转换为二阶统计模型,然后利用统计鲁棒设计形式来优化射频和磁场梯度波形。用8倍发射射频线圈进行7特斯拉脑成像的实验验证表明,这种新方法在计算效率方面有一定的好处。因此,对于由35张图组成的设计数据库,可以将最初50分钟的计算时间减少到3分钟。因此,所建议的统计方法可以集成大型数据库,这可能是确保健壮的解决方案所必需的。最后,它提供了计算翻转角统计数据的方法,以及用于质量保证的简单性能指标(RF脉冲性能)或TX阵列架构优化的指导。
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引用次数: 0
Solution of the Bloch Equations including Relaxation 包含松弛的Bloch方程的解
IF 0.4 4区 化学 Q4 CHEMISTRY, PHYSICAL Pub Date : 2020-09-02 DOI: 10.1155/2020/8819956
Eric R. Johnston

The magnetization differential equations of Bloch are integrated using a matrix diagonalization method. The solution describes several limiting cases and leads to compact expressions of wide validity for a spin ensemble initially at equilibrium.

采用矩阵对角化方法对布洛赫磁化微分方程进行了积分。该解描述了几种极限情况,并得到了初始处于平衡态的自旋系综具有广泛有效性的紧化表达式。
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引用次数: 0
Lineshape of Magnetic Resonance and its Effects on Free Induction Decay and Steady-State Free Precession Signal Formation 磁共振线形及其对自由感应衰减和稳态自由进动信号形成的影响
IF 0.4 4区 化学 Q4 CHEMISTRY, PHYSICAL Pub Date : 2020-01-19 DOI: 10.1155/2020/5057386
C. H. Ziener, M. Uhrig, T. Kampf, V. J. F. Sturm, F. T. Kurz, S. Heiland, M. Bendszus, M. Pham, P. M. Jakob, H.-P. Schlemmer, L. R. Buschle

Magnetic resonance imaging based on steady-state free precision (SSFP) sequences is a fast method to acquire T1, T2, and -weighted images. In inhomogeneous tissues such as lung tissue or blood vessel networks, however, microscopic field inhomogeneities cause a nonexponential free induction decay and a non-Lorentzian lineshape. In this work, the SSFP signal is analyzed for different prominent tissue models. Neglecting the effect of non-Lorentzian lineshapes can easily result in large errors of the determined relaxation times. Moreover, sequence parameters of SSFP measurements can be optimized for the nonexponential signal decay in many tissue structures.

基于稳态自由精度(SSFP)序列的磁共振成像是一种快速获取T1、T2和加权图像的方法。然而,在不均匀的组织中,如肺组织或血管网络,微观场的不均匀性会导致非指数自由诱导衰减和非洛伦兹线形。在这项工作中,分析了不同突出组织模型的SSFP信号。忽略非洛伦兹线形的影响很容易导致松弛时间的确定误差很大。此外,SSFP测量的序列参数可以针对许多组织结构中的非指数信号衰减进行优化。
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引用次数: 0
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Concepts in Magnetic Resonance Part A
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