Pub Date : 2025-11-07DOI: 10.1177/08465371251385534
Anand Dhatt, Nevin de Korompay, Manraj K S Heran, Matthew Ruo-Fan Chang, Stephen Ho, David M Liu, Leandro Cardarelli-Leite, Bruce Forster, Alison Harris, Ashley Rampuri, Erin Davidson, Ravjot Dhatt
Background: Physicians in Canada are disproportionately concentrated in urban centers, with rural regions facing significant gaps in specialist care. The geo-spatial characteristics of Interventional Radiology (IR) in Canada have not been systematically studied. This study examines the distribution of Canadian Association of Interventional Radiology (CAIR) members and the sociodemographic characteristics of the populations they serve.
Methods: A list of active members of the Canadian Association of IR (CAIR) was obtained in May 2025. Data from the Canadian Census was used to gather census division (CD)-level information on population size and demographics including data on ethnicity, income, education, employment, and income. CDs were grouped and compared between those with access to IR care and those without, compared between top and bottom quartiles for each population characteristic, and mapped.
Results: Of 293 CDs in Canada, only 48 (19.6%) had at least one CAIR IR, leaving 31.6% of the national population without local access. CAIR IRs were strongly clustered in high-population CDs, with Toronto, Vancouver, and Montreal alone accounting for 56.5% of IRs. CDs with CAIR IRs had significantly higher mean populations (527 322 vs 47 675; P < .001), median incomes ($82 760 vs $75 821; P = .002), and educational attainment (31% vs 16%; P < .001). Conversely, CDs with higher proportions of the population being Indigenous were less likely to have CAIR IRs (5% vs 14%; P < .001).
Conclusion: CAIR member IRs are disproportionately concentrated in large urban centers, leaving substantial geographic disparities. Addressing this maldistribution will require coordinated strategies, including outreach models, telehealth integration, and national workforce planning.
背景:加拿大的医生不成比例地集中在城市中心,农村地区在专科护理方面存在显著差距。加拿大介入放射学(IR)的地理空间特征尚未得到系统研究。本研究考察了加拿大介入放射学会(CAIR)成员的分布及其所服务人群的社会人口特征。方法:于2025年5月获得加拿大IR协会(CAIR)活跃会员名单。来自加拿大人口普查的数据用于收集人口规模和人口统计信息,包括种族、收入、教育、就业和收入数据。对CDs进行分组,并在获得IR护理的患者和未获得IR护理的患者之间进行比较,对每个人群特征的最高和最低四分位数进行比较,并绘制地图。结果:在加拿大293个cd中,只有48个(19.6%)至少有一个CAIR IR,其余31.6%的全国人口没有本地访问。CAIR ir强烈聚集在高人口密度的cd中,仅多伦多、温哥华和蒙特利尔就占ir的56.5%。患有CAIR ir的cd患者的平均人群明显更高(527 322 vs 47 675; P =。002)和受教育程度(31% vs 16%; P P结论:CAIR成员的ir不成比例地集中在大城市中心,留下了巨大的地理差异。解决这种分配不均问题需要协调战略,包括外联模式、远程保健一体化和国家劳动力规划。
{"title":"Understanding the Canadian Interventional Radiology Landscape Through the Canadian Association of Interventional Radiology Database: A Descriptive Study.","authors":"Anand Dhatt, Nevin de Korompay, Manraj K S Heran, Matthew Ruo-Fan Chang, Stephen Ho, David M Liu, Leandro Cardarelli-Leite, Bruce Forster, Alison Harris, Ashley Rampuri, Erin Davidson, Ravjot Dhatt","doi":"10.1177/08465371251385534","DOIUrl":"10.1177/08465371251385534","url":null,"abstract":"<p><strong>Background: </strong>Physicians in Canada are disproportionately concentrated in urban centers, with rural regions facing significant gaps in specialist care. The geo-spatial characteristics of Interventional Radiology (IR) in Canada have not been systematically studied. This study examines the distribution of Canadian Association of Interventional Radiology (CAIR) members and the sociodemographic characteristics of the populations they serve.</p><p><strong>Methods: </strong>A list of active members of the Canadian Association of IR (CAIR) was obtained in May 2025. Data from the Canadian Census was used to gather census division (CD)-level information on population size and demographics including data on ethnicity, income, education, employment, and income. CDs were grouped and compared between those with access to IR care and those without, compared between top and bottom quartiles for each population characteristic, and mapped.</p><p><strong>Results: </strong>Of 293 CDs in Canada, only 48 (19.6%) had at least one CAIR IR, leaving 31.6% of the national population without local access. CAIR IRs were strongly clustered in high-population CDs, with Toronto, Vancouver, and Montreal alone accounting for 56.5% of IRs. CDs with CAIR IRs had significantly higher mean populations (527 322 vs 47 675; <i>P</i> < .001), median incomes ($82 760 vs $75 821; <i>P</i> = .002), and educational attainment (31% vs 16%; <i>P</i> < .001). Conversely, CDs with higher proportions of the population being Indigenous were less likely to have CAIR IRs (5% vs 14%; <i>P</i> < .001).</p><p><strong>Conclusion: </strong>CAIR member IRs are disproportionately concentrated in large urban centers, leaving substantial geographic disparities. Addressing this maldistribution will require coordinated strategies, including outreach models, telehealth integration, and national workforce planning.</p>","PeriodicalId":55290,"journal":{"name":"Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes","volume":" ","pages":"8465371251385534"},"PeriodicalIF":3.7,"publicationDate":"2025-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145472459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-06DOI: 10.1177/08465371251387572
Rakhshan Kamran, Andrea Schwarz Doria, Michael N Patlas
Patient-reported outcome measures (PROMs) are standardized, validated instruments that measure how patients feel and function, collected directly from the patient. Traditionally, key metrics in radiology include technical aspects such as image quality, radiation dose, and diagnostic accuracy. However, medical imaging and image-guided therapies shape patient experience in informational, emotional, physical, and logistical domains that are rarely measured. Failing to capture this information is an important gap in radiology research and practice today that needs to be addressed. This review synthesizes the science of PROMs through a radiology lens: what PROMs are; why PROMs are relevant to diagnostic imaging and interventional practice; how to select and interpret PROMs responsibly, with explicit attention to bias, conflicts of interest, and minimal important differences; and how to implement PROMs pragmatically using contemporary digital workflows. This article highlights radiology-specific frameworks for patient-centred outcomes of diagnostic tests, summarizes evidence on how electronic PROM (ePROM) programs can improve patient experience and clinical outcomes, and proposes a practical roadmap for department-level implementation. Throughout, this review aligns recommendations with current methodological and regulatory guidance, draws on Canadian implementation experience, and translates lessons from applied PROM programs in complex clinical services to radiology settings. Implemented thoughtfully, PROMs give radiologists a rigorous, low-burden way to document benefits radiology already provides, strengthen outcome and health-economic analyses, and co-design services around what patients value. Integrating PROMs alongside established technical and diagnostic metrics can extend radiology's value proposition, and make radiology's patient-centred impact visible, measurable, and improvable.
{"title":"Measuring What Matters in Radiology: A Guide to Selecting, Implementing, and Interpreting Patient-Reported Outcome Measures.","authors":"Rakhshan Kamran, Andrea Schwarz Doria, Michael N Patlas","doi":"10.1177/08465371251387572","DOIUrl":"10.1177/08465371251387572","url":null,"abstract":"<p><p>Patient-reported outcome measures (PROMs) are standardized, validated instruments that measure how patients feel and function, collected directly from the patient. Traditionally, key metrics in radiology include technical aspects such as image quality, radiation dose, and diagnostic accuracy. However, medical imaging and image-guided therapies shape patient experience in informational, emotional, physical, and logistical domains that are rarely measured. Failing to capture this information is an important gap in radiology research and practice today that needs to be addressed. This review synthesizes the science of PROMs through a radiology lens: what PROMs are; why PROMs are relevant to diagnostic imaging and interventional practice; how to select and interpret PROMs responsibly, with explicit attention to bias, conflicts of interest, and minimal important differences; and how to implement PROMs pragmatically using contemporary digital workflows. This article highlights radiology-specific frameworks for patient-centred outcomes of diagnostic tests, summarizes evidence on how electronic PROM (ePROM) programs can improve patient experience and clinical outcomes, and proposes a practical roadmap for department-level implementation. Throughout, this review aligns recommendations with current methodological and regulatory guidance, draws on Canadian implementation experience, and translates lessons from applied PROM programs in complex clinical services to radiology settings. Implemented thoughtfully, PROMs give radiologists a rigorous, low-burden way to document benefits radiology already provides, strengthen outcome and health-economic analyses, and co-design services around what patients value. Integrating PROMs alongside established technical and diagnostic metrics can extend radiology's value proposition, and make radiology's patient-centred impact visible, measurable, and improvable.</p>","PeriodicalId":55290,"journal":{"name":"Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes","volume":" ","pages":"8465371251387572"},"PeriodicalIF":3.7,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-06DOI: 10.1177/08465371251386863
Adrian P Brady
Despite the centrality of radiology and radiologists in much clinical investigation and care of patients, the precise roles radiologists fulfil are often poorly understood by patients, and, sometimes, sadly, by our colleagues in healthcare. Loose use of language often designates those who refer patients for radiological investigation as "clinicians," implying that this descriptor does not apply to radiologists. The term "clinician" applies to physicians with direct responsibility for patient care; this includes typical radiologist activity. For a variety of reasons (personal preference, workload demands, modern methods of communication and working), direct contact between radiologists and patients, and between radiologists and referring colleagues is in decline. Yet this trend is occurring against a backdrop of increased reliance upon radiology and other investigative tests, as opposed to history-taking and physical examination, for diagnosis and management decision-making. Given the opportunity this trend creates for radiology and radiologists to demonstrate and enhance our clinical centrality, and the concurrent increasing expectation on the part of patients for direct interaction with those making decisions with respect to their healthcare, radiologists need to emphasise our clinical role by embracing every opportunity for direct contact with our patients and our referring colleagues, rather than allowing ourselves to become overwhelmed by and hidden behind ever-increasing workload. It is only by being true, active clinicians that radiologists can deliver most value for our patients, and ensure that our speciality prospers and grows.
{"title":"The Radiologist as a Clinician.","authors":"Adrian P Brady","doi":"10.1177/08465371251386863","DOIUrl":"10.1177/08465371251386863","url":null,"abstract":"<p><p>Despite the centrality of radiology and radiologists in much clinical investigation and care of patients, the precise roles radiologists fulfil are often poorly understood by patients, and, sometimes, sadly, by our colleagues in healthcare. Loose use of language often designates those who refer patients for radiological investigation as \"clinicians,\" implying that this descriptor does not apply to radiologists. The term \"clinician\" applies to physicians with direct responsibility for patient care; this includes typical radiologist activity. For a variety of reasons (personal preference, workload demands, modern methods of communication and working), direct contact between radiologists and patients, and between radiologists and referring colleagues is in decline. Yet this trend is occurring against a backdrop of increased reliance upon radiology and other investigative tests, as opposed to history-taking and physical examination, for diagnosis and management decision-making. Given the opportunity this trend creates for radiology and radiologists to demonstrate and enhance our clinical centrality, and the concurrent increasing expectation on the part of patients for direct interaction with those making decisions with respect to their healthcare, radiologists need to emphasise our clinical role by embracing every opportunity for direct contact with our patients and our referring colleagues, rather than allowing ourselves to become overwhelmed by and hidden behind ever-increasing workload. It is only by being true, active clinicians that radiologists can deliver most value for our patients, and ensure that our speciality prospers and grows.</p>","PeriodicalId":55290,"journal":{"name":"Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes","volume":" ","pages":"8465371251386863"},"PeriodicalIF":3.7,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-05DOI: 10.1177/08465371251383887
Bhavana Shyamanur, Korosh Khalili, Khaled Y Elbanna
Diffuse liver diseases, including steatosis, cirrhosis, and fibrosis, significantly alter hepatic architecture, and can obscure, mimic, or alter the imaging features of focal liver lesions and reduce the diagnostic accuracy of specific imaging modalities. This review outlines the key imaging pitfalls created by diffuse liver disease and offers practical, evidence-based strategies to overcome them. We describe several key imaging pitfalls in interpreting liver lesions in diffuse liver disease, including the atypical appearance of focal lesions on ultrasound and CT due to altered background parenchyma; the phenomenon of "vanishing washout" of hepatocellular carcinoma on CT in steatotic livers; and the significant risk of underestimating metastatic disease burden or missing occult lesions. For each pitfall, we discuss the strengths and weaknesses of various imaging modalities and suggest problem-solving strategies, such as guidance on selecting the most appropriate next-line imaging modality for lesion characterization. We highlight the roles of contrast-enhanced ultrasound and MRI in resolving diagnostic uncertainty when initial ultrasound or CT imaging is atypical or equivocal. A comprehensive understanding of how diffuse liver disease affects the imaging of both benign and malignant lesions is important for accurate diagnosis. Recognizing these pitfalls allows a tailored, multimodality imaging approach that optimizes the detection and characterization of focal liver lesions, ultimately guiding clinical management and improving patient care.
{"title":"The Impact of Diffuse Liver Disease on Liver Lesion Detection and Characterization.","authors":"Bhavana Shyamanur, Korosh Khalili, Khaled Y Elbanna","doi":"10.1177/08465371251383887","DOIUrl":"https://doi.org/10.1177/08465371251383887","url":null,"abstract":"<p><p>Diffuse liver diseases, including steatosis, cirrhosis, and fibrosis, significantly alter hepatic architecture, and can obscure, mimic, or alter the imaging features of focal liver lesions and reduce the diagnostic accuracy of specific imaging modalities. This review outlines the key imaging pitfalls created by diffuse liver disease and offers practical, evidence-based strategies to overcome them. We describe several key imaging pitfalls in interpreting liver lesions in diffuse liver disease, including the atypical appearance of focal lesions on ultrasound and CT due to altered background parenchyma; the phenomenon of \"vanishing washout\" of hepatocellular carcinoma on CT in steatotic livers; and the significant risk of underestimating metastatic disease burden or missing occult lesions. For each pitfall, we discuss the strengths and weaknesses of various imaging modalities and suggest problem-solving strategies, such as guidance on selecting the most appropriate next-line imaging modality for lesion characterization. We highlight the roles of contrast-enhanced ultrasound and MRI in resolving diagnostic uncertainty when initial ultrasound or CT imaging is atypical or equivocal. A comprehensive understanding of how diffuse liver disease affects the imaging of both benign and malignant lesions is important for accurate diagnosis. Recognizing these pitfalls allows a tailored, multimodality imaging approach that optimizes the detection and characterization of focal liver lesions, ultimately guiding clinical management and improving patient care.</p>","PeriodicalId":55290,"journal":{"name":"Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes","volume":" ","pages":"8465371251383887"},"PeriodicalIF":3.7,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145446669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-06-11DOI: 10.1177/08465371251348835
Francois H Cornelis
{"title":"Response to Editorial on \"The Current and Future Landscape of Interventional Neuro-Oncology\".","authors":"Francois H Cornelis","doi":"10.1177/08465371251348835","DOIUrl":"10.1177/08465371251348835","url":null,"abstract":"","PeriodicalId":55290,"journal":{"name":"Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes","volume":" ","pages":"572"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-02-27DOI: 10.1177/08465371251323107
Parthiv Amin, Aleena Malik, Matthew D F Mcinnes, Maura J Brown, Andrew Szava-Kovats
The rising global burden of cancer drives increased demands for medical imaging, which is essential throughout cancer care. However, delivering medical imaging presents significant environmental challenges including high energy use, reliance on single-use supplies, and the production of environmental pollutants. Environmental factors, such as ultraviolet radiation, wildfire smoke, and carcinogenic pollutants contribute to rising cancer rates, while extreme weather events driven by climate change disrupt cancer care delivery-highlighting the close connection between patient and planetary health. This review explores opportunities to improve the environmental sustainability of oncologic imaging, emphasizing the importance of patient-relevant outcomes-such as quality of life and overall survival-as a guiding principle in cancer care. Key strategies include optimizing imaging schedules to reduce low-value imaging, selecting modalities with lower environmental impact where clinically appropriate, minimizing waste streams, and adopting energy-efficient practices. Artificial intelligence offers the potential to personalize imaging schedules and improve efficiency, though its benefits must be weighed against energy use. Mobile imaging programs and integrated scheduling reduce patient travel-related emissions while promoting health equity, particularly in underserved communities. Future research should focus on optimizing imaging intervals to address patient-relevant outcomes better, expanding the use of abbreviated imaging protocols, and the judicious deployment of artificial intelligence, ensuring its benefits justify energy use.
{"title":"Environmental Sustainability and Cancer Imaging.","authors":"Parthiv Amin, Aleena Malik, Matthew D F Mcinnes, Maura J Brown, Andrew Szava-Kovats","doi":"10.1177/08465371251323107","DOIUrl":"10.1177/08465371251323107","url":null,"abstract":"<p><p>The rising global burden of cancer drives increased demands for medical imaging, which is essential throughout cancer care. However, delivering medical imaging presents significant environmental challenges including high energy use, reliance on single-use supplies, and the production of environmental pollutants. Environmental factors, such as ultraviolet radiation, wildfire smoke, and carcinogenic pollutants contribute to rising cancer rates, while extreme weather events driven by climate change disrupt cancer care delivery-highlighting the close connection between patient and planetary health. This review explores opportunities to improve the environmental sustainability of oncologic imaging, emphasizing the importance of patient-relevant outcomes-such as quality of life and overall survival-as a guiding principle in cancer care. Key strategies include optimizing imaging schedules to reduce low-value imaging, selecting modalities with lower environmental impact where clinically appropriate, minimizing waste streams, and adopting energy-efficient practices. Artificial intelligence offers the potential to personalize imaging schedules and improve efficiency, though its benefits must be weighed against energy use. Mobile imaging programs and integrated scheduling reduce patient travel-related emissions while promoting health equity, particularly in underserved communities. Future research should focus on optimizing imaging intervals to address patient-relevant outcomes better, expanding the use of abbreviated imaging protocols, and the judicious deployment of artificial intelligence, ensuring its benefits justify energy use.</p>","PeriodicalId":55290,"journal":{"name":"Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes","volume":" ","pages":"611-622"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-02-28DOI: 10.1177/08465371251322762
Felipe Castillo, Omar Taboun, John Farag Alla, Karyna Yankova, Kate Hanneman
Climate change is the most important challenge of this century. Global surface temperature is continuously rising to new record highs, adversely affecting the health of the planet and humans. The purpose of this article is to review the impact of climate related environmental exposures on human health, healthcare delivery, and medical imaging and explore the potential to leverage medical imaging as a non-invasive tool to advance our understanding of climate related health effects. Radiology departments and healthcare systems must focus on building resilience to the effects of climate change while ensuring that the delivery of care is environmentally sustainable. Further research is needed to refine our understanding of the effects of climate change on human health and to forecast the expected changes in the demand for healthcare and radiology services.
{"title":"Imaging Climate-Related Environmental Exposures: Impact and Opportunity.","authors":"Felipe Castillo, Omar Taboun, John Farag Alla, Karyna Yankova, Kate Hanneman","doi":"10.1177/08465371251322762","DOIUrl":"10.1177/08465371251322762","url":null,"abstract":"<p><p>Climate change is the most important challenge of this century. Global surface temperature is continuously rising to new record highs, adversely affecting the health of the planet and humans. The purpose of this article is to review the impact of climate related environmental exposures on human health, healthcare delivery, and medical imaging and explore the potential to leverage medical imaging as a non-invasive tool to advance our understanding of climate related health effects. Radiology departments and healthcare systems must focus on building resilience to the effects of climate change while ensuring that the delivery of care is environmentally sustainable. Further research is needed to refine our understanding of the effects of climate change on human health and to forecast the expected changes in the demand for healthcare and radiology services.</p>","PeriodicalId":55290,"journal":{"name":"Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes","volume":" ","pages":"577-587"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-05-17DOI: 10.1177/08465371251340249
Ruben Geevarghese, Eric Lis, Marc Cohen, Andrew Lin, Viviane Tabar, Stephen B Solomon, Francois H Cornelis
Interventional neuro-oncology is an evolving subspecialty that leverages minimally invasive endovascular and percutaneous techniques to improve outcomes for patients with spine, brain, and head-neck tumours. While conventional interventions have historically focused on vascular pathologies such as stroke and aneurysms, interventional techniques in oncology are gaining prominence. This review explores the role of image-guided interventions in preoperative tumour embolization, middle meningeal artery embolization in thrombocytopenic cancer patients, management of head and neck hemorrhage, intra-arterial drug delivery, and spinal interventions. Through a synthesis of current evidence, we highlighted the growing importance of interventional techniques in neuro-oncology and discuss future advancements in image guidance, robotics, and targeted drug delivery.
{"title":"Interventional Neuro-Oncology: Expanding the Frontiers of Image-Guided Therapy.","authors":"Ruben Geevarghese, Eric Lis, Marc Cohen, Andrew Lin, Viviane Tabar, Stephen B Solomon, Francois H Cornelis","doi":"10.1177/08465371251340249","DOIUrl":"10.1177/08465371251340249","url":null,"abstract":"<p><p>Interventional neuro-oncology is an evolving subspecialty that leverages minimally invasive endovascular and percutaneous techniques to improve outcomes for patients with spine, brain, and head-neck tumours. While conventional interventions have historically focused on vascular pathologies such as stroke and aneurysms, interventional techniques in oncology are gaining prominence. This review explores the role of image-guided interventions in preoperative tumour embolization, middle meningeal artery embolization in thrombocytopenic cancer patients, management of head and neck hemorrhage, intra-arterial drug delivery, and spinal interventions. Through a synthesis of current evidence, we highlighted the growing importance of interventional techniques in neuro-oncology and discuss future advancements in image guidance, robotics, and targeted drug delivery.</p>","PeriodicalId":55290,"journal":{"name":"Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes","volume":" ","pages":"740-749"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-05-04DOI: 10.1177/08465371251335170
Maxime Barat, Mohamed Eltaher, Ahmed W Moawad, Philippe Soyer, David Fuentes, Marianne Golse, Anne Jouinot, Ayahallah A Ahmed, Mostafa A Shehata, Guillaume Assié, Mohab M Elmohr, Magalie Haissaguerre, Mouhammed A Habra, Christine Hoeffel, Khaled M Elsayes, Jérome Bertherat, Anthony Dohan
Purpose: Adrenocortical carcinoma (ACC) is a rare condition with a poor and hardly predictable prognosis. This study aims to build and evaluate a preoperative computed tomography (CT)-based score (CT score) using features previously reported as biomarkers in ACC to predict overall survival (OS) in patients with ACC. Methods: A CT score based on preoperative CT examinations combining shape elongation, maximum tumour diameter, and the European Network for the Study of Adrenal Tumors (ENSAT) stage was built using a logistic regression model to predict OS duration in a development cohort of 89 patients with ACC. An optimal cut-off of the CT score was defined and the Kaplan-Meier method was used to assess OS. The CT score was then tested in an external validation cohort of 54 patients wit ACC. The C-index of the CT score for predicting OS was compared to that of ENSAT stage alone. Results: The CT score helped discriminate between patients with poor prognosis and patients with good prognosis in both the validation cohort (54 patients; mean OS, 69.4 months; 95% confidence interval [CI]: 57.4-81.4 months vs mean OS, 75.6 months; 95% CI: 62.9-88.4 months, respectively; P = .022). In the validation cohort the C-index of the CT score was significantly better than that of the ENSAT stage alone (0.62 vs 0.35; P = .002). Conclusion: A CT score combining morphological criteria, radiomics, and ENSAT stage on preoperative CT examinations allows a better prognostic stratification of patients with ACC compared to ENSAT stage alone.
目的:肾上腺皮质癌(ACC)是一种罕见的疾病,预后差且难以预测。本研究旨在建立和评估术前基于计算机断层扫描(CT)的评分(CT评分),使用先前报道的ACC生物标志物的特征来预测ACC患者的总生存期(OS)。方法:基于术前CT检查,结合形状延伸,最大肿瘤直径和欧洲肾上腺肿瘤研究网络(ENSAT)分期,使用logistic回归模型建立CT评分,预测89例ACC患者的发展队列的OS持续时间。定义CT评分的最佳截止点,并采用Kaplan-Meier法评估OS。然后在54例ACC患者的外部验证队列中测试CT评分。将CT评分预测OS的c指数与单独的ENSAT分期进行比较。结果:CT评分有助于在验证队列(54例;平均OS为69.4个月;95%置信区间[CI]: 57.4-81.4个月,平均OS为75.6个月;95% CI: 62.9-88.4个月;P = .022)。在验证队列中,CT评分的c指数明显优于单独的ENSAT期(0.62 vs 0.35;P = .002)。结论:与单独的ENSAT分期相比,结合形态学标准、放射组学和术前CT检查的ENSAT分期的CT评分可以更好地对ACC患者进行预后分层。
{"title":"A Computed Tomography-Based Score to Predict Survival in Patients With Adrenocortical Carcinoma: A Proof-of-Concept Study.","authors":"Maxime Barat, Mohamed Eltaher, Ahmed W Moawad, Philippe Soyer, David Fuentes, Marianne Golse, Anne Jouinot, Ayahallah A Ahmed, Mostafa A Shehata, Guillaume Assié, Mohab M Elmohr, Magalie Haissaguerre, Mouhammed A Habra, Christine Hoeffel, Khaled M Elsayes, Jérome Bertherat, Anthony Dohan","doi":"10.1177/08465371251335170","DOIUrl":"10.1177/08465371251335170","url":null,"abstract":"<p><p><b>Purpose:</b> Adrenocortical carcinoma (ACC) is a rare condition with a poor and hardly predictable prognosis. This study aims to build and evaluate a preoperative computed tomography (CT)-based score (CT score) using features previously reported as biomarkers in ACC to predict overall survival (OS) in patients with ACC. <b>Methods:</b> A CT score based on preoperative CT examinations combining shape elongation, maximum tumour diameter, and the European Network for the Study of Adrenal Tumors (ENSAT) stage was built using a logistic regression model to predict OS duration in a development cohort of 89 patients with ACC. An optimal cut-off of the CT score was defined and the Kaplan-Meier method was used to assess OS. The CT score was then tested in an external validation cohort of 54 patients wit ACC. The C-index of the CT score for predicting OS was compared to that of ENSAT stage alone. <b>Results:</b> The CT score helped discriminate between patients with poor prognosis and patients with good prognosis in both the validation cohort (54 patients; mean OS, 69.4 months; 95% confidence interval [CI]: 57.4-81.4 months vs mean OS, 75.6 months; 95% CI: 62.9-88.4 months, respectively; <i>P</i> = .022). In the validation cohort the C-index of the CT score was significantly better than that of the ENSAT stage alone (0.62 vs 0.35; <i>P</i> = .002). <b>Conclusion:</b> A CT score combining morphological criteria, radiomics, and ENSAT stage on preoperative CT examinations allows a better prognostic stratification of patients with ACC compared to ENSAT stage alone.</p>","PeriodicalId":55290,"journal":{"name":"Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes","volume":" ","pages":"683-691"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-06-11DOI: 10.1177/08465371251347859
Iain D C Kirkpatrick
{"title":"Yesterday's Plombage, Today's Bypass, Tomorrow's Pill.","authors":"Iain D C Kirkpatrick","doi":"10.1177/08465371251347859","DOIUrl":"10.1177/08465371251347859","url":null,"abstract":"","PeriodicalId":55290,"journal":{"name":"Canadian Association of Radiologists Journal-Journal De L Association Canadienne Des Radiologistes","volume":" ","pages":"570-571"},"PeriodicalIF":3.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}