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Poor Sleep Quality, Mobile Phone Addiction, and Depressive Symptoms Among College Students: A Three-Wave Longitudinal Study. 大学生睡眠质量差、手机成瘾和抑郁症状:一项三波纵向研究
IF 1.6 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-10-21 DOI: 10.1080/15402002.2025.2569375
Tongyan Deng, Weiqiang Yu, Yu Liu, Shuqin Li, JingYi Xu, Yifan Wang, Rui Wang, Xianbing Song, Tian Xing, Yuhui Wan

Background: This study employed a multilevel autoregressive mediation model to clarify the longitudinal role of poor sleep quality in the association between mobile-phone addiction and depressive symptoms among Chinese college students.

Methods: 3,662 freshmen (976 Male/2,686 Female) from two Anhui colleges were assessed at T1 (November 2019, N = 4,211), T2 (May 2020, N = 4,193) and T3 (November 2020, N = 3,662) for sleep quality, mobile-phone addiction and depressive symptoms.

Results: Correlation analysis revealed significant associations between smartphone addiction (β = 0.493, 0.391, p <0.001), sleep problems (β = 0.336, 0.318, p <0.001), and depressive symptoms (β = 0.488, 0.431, p <0.001) across T1, T2 and T3 . Positive associations were observed between smartphone addiction and both sleep problems and depressive symptoms (β = 0.343, 0.329 at T1; β = 0.381, 0.402 at T2; β = 0.315, 0.261 at T3; all p < 0.001). A simple mediation model revealed that poor sleep quality partially mediated the association between mobile phone addiction and depressive symptoms among college students (indirect effect β = 0.0505, p < 0.001; total effect β = 0.237, p < 0.001). The multilevel autoregressive mediation model further confirmed that poor sleep quality partially mediated this association (indirect effect β = 0.002, p < 0.05; total effect β = 0.047, p < 0.001).

Conclusion: This study underscores poor sleep quality as a critical mediating factor in the long-term relationship between mobile phone addiction and depressive symptoms among Chinese college students.

背景:本研究采用多层次自回归中介模型来阐明睡眠质量差在中国大学生手机成瘾与抑郁症状关联中的纵向作用。方法:在T1(2019年11月,N = 4,211)、T2(2020年5月,N = 4,193)和T3(2020年11月,N = 3,662)对安徽省两所高校的3,662名新生(男976人/女2,686人)进行睡眠质量、手机成瘾和抑郁症状评估。结果:相关分析显示,智能手机成瘾与青少年之间存在显著相关性(T1时β = 0.493、0.391,p β = 0.336、0.318,p β = 0.488、0.431,p β = 0.343、0.329,T2时β = 0.381、0.402,T3时β = 0.315、0.261,均p < 0.001)。一个简单的中介模型显示,睡眠质量差在手机成瘾与大学生抑郁症状之间存在部分中介作用(间接效应β = 0.0505, p < 0.001;总效应β = 0.237, p < 0.001)。多层次自回归中介模型进一步证实,睡眠质量差部分介导了这种关联(间接效应β = 0.002, p < 0.05;总效应β = 0.047, p < 0.001)。结论:本研究强调睡眠质量差是中国大学生手机成瘾与抑郁症状长期关系的重要中介因素。
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引用次数: 0
A Case Series of Group Videoconference-Delivered Cognitive-Behavioral Therapy with Morning Light Therapy in Adolescents with Delayed Sleep Timing. 小组视频会议提供的认知行为疗法与晨光疗法对睡眠时间延迟的青少年的案例系列。
IF 1.6 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-10-09 DOI: 10.1080/15402002.2025.2569376
Emily J Ricketts, Ariel J Rissman, Valerie S Swisher, Daniel S Joyce, Christopher S Colwell, Helen J Burgess

Objectives: This case series examined the feasibility and preliminary effects of group-based, videoconference-delivered cognitive-behavioral therapy (CBT) combined with morning light therapy (LT) in adolescents with delayed sleep timing.

Method: Five females aged 14-16 years (M = 15.0, SD = 0.7) completed clinician-administered screening interviews, and baseline and post-treatment assessments, including circadian phase measurement, and validated measures of chronotype, bedtime procrastination, pre-sleep arousal, daytime sleepiness, anxiety, depression, and quality of life. Actigraphy was used for the duration of the study. The intervention included six weekly CBT sessions and short-wavelength wearable LT assigned for 1 hr daily following an advancing wake time schedule.

Results: One participant showed a 94-min circadian phase advance; others showed minimal phase advance, no change, or phase delays (n = 2). All participants reported earlier chronotype by post-treatment. Three advanced either sleep onset or wake time, with one showing both. Two showed increased total sleep time, primarily due to delayed wake time. Other objective sleep outcomes are presented. Bedtime procrastination, pre-sleep arousal, daytime sleepiness, depression, and quality of life improved, with modest reductions in anxiety. Challenges included napping, ADHD and anxiety comorbidity, scheduling barriers (homework, extracurricular activities, screen use), and resistance to earlier bedtimes.

Conclusions: Results suggest heterogeneous circadian and sleep responses but consistent behavioral improvements. Extended LT duration, motivational enhancement, executive function or time management strategies, and behavioral economics-informed interventions may improve engagement and treatment efficacy.

目的:本病例系列研究了基于小组的、视频会议提供的认知行为疗法(CBT)联合晨光疗法(LT)治疗睡眠时间延迟的青少年的可行性和初步效果。方法:5名年龄在14-16岁的女性(M = 15.0, SD = 0.7)完成了临床管理的筛查访谈,以及基线和治疗后评估,包括昼夜节律阶段测量,以及时间型、睡前拖延症、睡前唤醒、白天嗜睡、焦虑、抑郁和生活质量的验证测量。在研究期间使用活动描记术。干预包括每周6次的CBT治疗和每天1小时的短波可穿戴LT。结果:一名参与者表现出94分钟的昼夜节律期提前;另一些患者表现出最小的相位提前,没有变化或相位延迟(n = 2)。所有参与者在治疗后报告了较早的时型。三个人要么提前了睡眠开始时间,要么提前了起床时间,其中一个人两者都提前了。其中两组显示总睡眠时间增加,主要是由于醒来时间推迟。提出了其他客观的睡眠结果。睡前拖延症、睡前觉醒、白天嗜睡、抑郁和生活质量得到改善,焦虑有所减少。挑战包括午睡、多动症和焦虑共病、日程安排障碍(家庭作业、课外活动、屏幕使用)以及抵制早睡。结论:结果表明昼夜节律和睡眠反应不同,但行为改善一致。延长LT持续时间、动机增强、执行功能或时间管理策略以及行为经济学干预可以改善参与和治疗效果。
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引用次数: 0
Sleep Hygiene Among Adolescents Clinically Referred to Behavioral Sleep Medicine: Comparisons to the Validation Sample and Associations with Sleep Problems. 临床行为睡眠医学中青少年的睡眠卫生:与验证样本的比较以及与睡眠问题的关联。
IF 1.6 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-05-19 DOI: 10.1080/15402002.2025.2506446
Andrea L Fidler, Tori R Van Dyk, Danielle M Simmons, Kristina Decker, Kelly C Byars

Objectives: 1) Compare the sleep hygiene of our clinical sample to the community-based validation sample and established clinical thresholds and 2) clarify the relationship between sleep hygiene and sleep problems in adolescents referred for Behavioral Sleep Medicine (BSM) treatment.

Methods: Clinical participants included BSM patients aged 11-18 years (n = 354) with insomnia. Adolescents completed the Adolescent Sleep Hygiene Scale (ASHS) and the Pediatric Insomnia Severity Index. Caregivers completed the Sleep Disorders Inventory for Students. Independent samples t-tests compared sleep hygiene between our clinical sample and the community-based ASHS validation sample (572 American adolescents). We report which sleep hygiene subscales fell below thresholds indicating clinically significant problems. Multiple linear regressions determined whether demographics and sleep hygiene subscales predicted sleep problems.

Results: Adolescents referred to our BSM clinic had better overall sleep hygiene than the community-based validation sample, p < .001. They had inadequate sleep hygiene practices related to sleep stability, behavioral arousal, and cognitive/emotional arousal. Demographics and sleep hygiene factors significantly predicted both adolescent-reported insomnia severity and caregiver-reported sleep disturbance, ps < 0.001.

Conclusion: Poor sleep hygiene may result from maladaptive coping and can compound existing sleep problems. It is important to have consistent definitions of sleep hygiene that limit overlap with other key intervention targets.

目的:1)将临床样本的睡眠卫生与社区验证样本和建立的临床阈值进行比较;2)阐明接受行为睡眠医学(BSM)治疗的青少年睡眠卫生与睡眠问题之间的关系。方法:临床研究对象为11-18岁伴有失眠的BSM患者(n = 354)。青少年完成青少年睡眠卫生量表(ASHS)和儿童失眠严重程度指数。护理人员完成了学生睡眠障碍量表。独立样本t检验比较了临床样本和社区ASHS验证样本(572名美国青少年)的睡眠卫生状况。我们报告哪些睡眠卫生量表低于阈值,表明有临床意义的问题。多元线性回归确定了人口统计学和睡眠卫生亚量表是否能预测睡眠问题。结果:与社区验证样本相比,BSM门诊青少年的整体睡眠卫生状况较好。结论:睡眠卫生状况不佳可能是由于适应不良导致的,并可能使已有的睡眠问题复杂化。重要的是要有一致的睡眠卫生定义,以限制与其他关键干预目标的重叠。
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引用次数: 0
A Mixed-methods Systematic Review of Sleep Duration and Quality in Healthcare Workers: Impacts on Patient Safety and Quality of Care. 一项对医护人员睡眠时间和质量的混合方法系统评价:对患者安全和护理质量的影响。
IF 1.6 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-06-19 DOI: 10.1080/15402002.2025.2522682
Jordan Fox, Matthew McGrail, Yu Jin Cha, Daisy Cho, Raymond Weimeng Lu, Roy Yi, Priya Martin

Objectives: The aim of this systematic review was to synthesize evidence on the impacts of sleep duration and quality in healthcare workers on patient safety and quality of care. A secondary aim was to understand the impact of shiftwork and workload characteristics alongside sleep duration and quality.

Methods: A systematic search of Scopus, PubMed, Embase, APA PsycINFO, and CINAHL databases was completed in May 2023 and updated in December 2024. Only studies published in English from 2013 onwards were considered for inclusion in the review. Quality appraisal of included studies was conducted via the McMaster tools for quantitative and qualitative studies, respectively, and results were synthesized and presented as a narrative summary.

Results: Database searching revealed 7,422 results, with 30 studies eventually included in the review. Studies consistently showed that short sleep duration in healthcare workers was associated with worse patient safety (increased errors and poorer cognitive functioning). There was also a clear link between shiftwork and long shifts with reduced patient safety.

Conclusions: The majority of included studies revealed that patient safety and quality of care are worse where HCWs experience short duration and/or low-quality sleep or are working long and/or irregular shifts.

目的:本系统综述的目的是综合有关医护人员睡眠时间和睡眠质量对患者安全和护理质量影响的证据。第二个目的是了解轮班工作和工作量特征以及睡眠时间和质量的影响。方法:系统检索Scopus、PubMed、Embase、APA PsycINFO和CINAHL数据库,检索时间为2023年5月,更新时间为2024年12月。只有2013年以后用英语发表的研究才被纳入综述。分别通过麦克马斯特定量和定性研究工具对纳入的研究进行质量评估,并对结果进行综合并以叙述性摘要的形式呈现。结果:数据库检索显示了7422项结果,其中30项研究最终纳入了综述。研究一致表明,卫生保健工作者睡眠时间短与患者安全性较差(错误增加和认知功能较差)有关。倒班和长时间倒班与降低病人安全之间也有明显的联系。结论:大多数纳入的研究表明,当医护人员经历短时间和/或低质量睡眠或工作时间长和/或轮班不规律时,患者的安全和护理质量更差。
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引用次数: 0
Development and Preliminary Validation of a Novel Tool to Measure Negative and Positive Affect for Sleep (NAP-AS). 一种测量睡眠消极和积极影响的新工具(NAP-AS)的开发和初步验证。
IF 1.6 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-07-21 DOI: 10.1080/15402002.2025.2508768
Caitlin Dow, Samuel Wilson, William R McMahon, Jessica E Manousakis, Caroline J Beatty, Rowan P Ogeil, Clare Anderson

Objectives: The PANAS is the most widely used measure to detect changes in mood following sleep loss. Although insufficient sleep is associated with enhanced negativity, negative affect items on the PANAS appear unaffected. We examined whether PANAS items were deemed relevant to sleep and subsequently developed a novel tool reflecting changes in negative and positive affect with sleep (NAP-AS).

Methods: Four hundred and forty-nine online respondents (18-79y) indicated the extent to which 100 positive and negative word-items (n = 48 new; n = 52 from any PANAS) were useful in describing the experience of insufficient sleep. Using factor analysis, a new questionnaire to reflect changing mood in relation to insufficient sleep was developed and validated under sleep deprivation conditions (n = 24, 18-34y).

Results: Four out of 10 original negative affect (NA) PANAS items (and 0/10 positive affect (PA) items) were deemed irrelevant to sleep by >50% of respondents ("guilt", "afraid", "scared", "ashamed"). To address this, we developed the NAP-AS using factor analysis (from 100 word items) resulting in 14 items reflecting NA and PA (71.4% new items for PA and NA equally; final fit model: RMSEA = 0.048, CFI = 0.98). In a validation study, this tool was sensitive to sleep deprivation (p < .001), such that NA significantly increased (p = .017, d > 0.47), while PA decreased (p < .001, d > 0.75), relative to when well-rested.

Conclusions: Despite the PANAS being a valid tool assessing changes in affect, several items appear irrelevant to the experience of poor sleep. The NAP-AS was developed to specifically capture changes in positive and negative affect following insufficient sleep. The new tool was sensitive to sleep loss, although further validation for clinical populations is recommended.

目的:PANAS是最广泛用于检测睡眠缺失后情绪变化的方法。虽然睡眠不足与消极情绪的增强有关,但PANAS上的消极影响项目似乎不受影响。我们研究了PANAS项目是否被认为与睡眠有关,并随后开发了一种反映睡眠消极和积极影响变化的新工具(NAP-AS)。方法:449名18-79岁的在线被调查者表示100个积极和消极词项(n = 48 new;n = 52)在描述睡眠不足的经历时是有用的。采用因子分析方法,在睡眠剥夺条件下(n = 24,18 -34y)编制并验证了一份反映睡眠不足与情绪变化关系的新问卷。结果:有50%的受访者认为10个原始消极情绪(NA)项中有4个与睡眠无关(0/10的积极情绪(PA)项)(“内疚”、“害怕”、“害怕”、“羞愧”)。为了解决这个问题,我们使用因子分析(从100个单词的条目中)开发了NAP-AS,结果产生了14个反映NA和PA的条目(71.4%的新条目为PA和NA;最终拟合模型:RMSEA = 0.048, CFI = 0.98)。在一项验证研究中,该工具对睡眠剥夺很敏感(p p =。017, d > 0.47),而相对于充分休息时,PA降低(p 0.75)。结论:尽管PANAS是评估影响变化的有效工具,但有几个项目似乎与睡眠质量差无关。开发NAP-AS是为了专门捕捉睡眠不足后积极和消极情绪的变化。新工具对睡眠缺失很敏感,但建议对临床人群进行进一步验证。
{"title":"Development and Preliminary Validation of a Novel Tool to Measure Negative and Positive Affect for Sleep (NAP-AS).","authors":"Caitlin Dow, Samuel Wilson, William R McMahon, Jessica E Manousakis, Caroline J Beatty, Rowan P Ogeil, Clare Anderson","doi":"10.1080/15402002.2025.2508768","DOIUrl":"10.1080/15402002.2025.2508768","url":null,"abstract":"<p><strong>Objectives: </strong>The PANAS is the most widely used measure to detect changes in mood following sleep loss. Although insufficient sleep is associated with enhanced negativity, negative affect items on the PANAS appear unaffected. We examined whether PANAS items were deemed relevant to sleep and subsequently developed a novel tool reflecting changes in negative and positive affect with sleep (NAP-AS).</p><p><strong>Methods: </strong>Four hundred and forty-nine online respondents (18-79y) indicated the extent to which 100 positive and negative word-items (<i>n</i> = 48 new; <i>n</i> = 52 from any PANAS) were useful in describing the experience of insufficient sleep. Using factor analysis, a new questionnaire to reflect changing mood in relation to insufficient sleep was developed and validated under sleep deprivation conditions (<i>n</i> = 24, 18-34y).</p><p><strong>Results: </strong>Four out of 10 original negative affect (NA) PANAS items (and 0/10 positive affect (PA) items) were deemed irrelevant to sleep by >50% of respondents (\"guilt\", \"afraid\", \"scared\", \"ashamed\"). To address this, we developed the NAP-AS using factor analysis (from 100 word items) resulting in 14 items reflecting NA and PA (71.4% new items for PA and NA equally; final fit model: RMSEA = 0.048, CFI = 0.98). In a validation study, this tool was sensitive to sleep deprivation (<i>p</i> < .001), such that NA significantly increased (<i>p</i> = .017, d > 0.47), while PA decreased (<i>p</i> < .001, d > 0.75), relative to when well-rested.</p><p><strong>Conclusions: </strong>Despite the PANAS being a valid tool assessing changes in affect, several items appear irrelevant to the experience of poor sleep. The NAP-AS was developed to specifically capture changes in positive and negative affect following insufficient sleep. The new tool was sensitive to sleep loss, although further validation for clinical populations is recommended.</p>","PeriodicalId":55393,"journal":{"name":"Behavioral Sleep Medicine","volume":" ","pages":"633-647"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mental Health, Substance Use, and Related Factors Associated with Recent Use of Cannabis for Sleep: A Co-Twin Control Study. 精神健康、物质使用以及与近期使用大麻睡眠相关的相关因素:一项双胞对照研究
IF 1.6 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-05-22 DOI: 10.1080/15402002.2025.2508770
Zoë Panchal, Joseph Sakai, Andrea N Goldstein-Piekarski, Jarrod M Ellingson, William Iacono, Robin P Corley, Scott Vrieze, Christian J Hopfer, John K Hewitt, Matt K McGue, J Megan Ross

Objectives: To examine: 1) cross-sectional associations between past-month use of cannabis for sleep with mental health, substance use, and related factors in adults and 2) the role of genetic and early environmental factors shared by twins (familial confounds) in explaining significant associations.

Methods: In a population-based sample of adult twins (n = 3,165, Mage36.7) we ran regression (phenotypic) and multilevel (co-twin control) models examining associations between past-month use of cannabis for sleep without comes of interest. We controlled for cannabis frequency and sleep quality except when each was the outcome of interest.

Results: Recent use of cannabis for sleep was associated with multiple mental health, substance use, and related factors in phenotypic models. In co-twincontrol models, within-family effects were significant between using cannabis for sleep with more problems from cannabis use, higher cannabis frequency, worse sleep quality, and more frequent use of alcohol and medication for sleep.

Conclusions: Familial confounds may explain many, but not all, associations between recent use of cannabis for sleep and mental health, substance use, and related factors. Longitudinal work is needed to clarify the directionality of associations not explained by familial confounds, and whether they are risks of using cannabis for sleep.

目的:检验:1)过去一个月使用大麻睡眠与成人心理健康、物质使用和相关因素之间的横断面关联;2)双胞胎共有的遗传和早期环境因素(家族混淆)在解释显著关联中的作用。方法:在以人口为基础的成年双胞胎样本(n = 3,165, Mage36.7)中,我们运行回归(表型)和多水平(双胎对照)模型,检查过去一个月在没有兴趣的情况下使用大麻用于睡眠之间的关系。我们控制了吸食大麻的频率和睡眠质量,除非两者都是我们感兴趣的结果。结果:在表型模型中,近期使用大麻用于睡眠与多种精神健康、物质使用和相关因素相关。在双胎对照模型中,家庭内部效应显著:使用大麻睡眠问题更多,使用大麻频率更高,睡眠质量更差,更频繁地使用酒精和药物来睡眠。结论:家族混淆可以解释近期使用大麻睡眠与精神健康、物质使用和相关因素之间的许多关联,但不是全部。需要进行纵向研究,以澄清家族混杂因素无法解释的关联的方向性,以及它们是否存在使用大麻睡眠的风险。
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引用次数: 0
Prevention of Pain Interference in Insomnia Patients via Digital Cognitive-Behavioral Therapy for Insomnia. 数字认知行为疗法对失眠患者疼痛干扰的预防
IF 1.6 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-05-05 DOI: 10.1080/15402002.2025.2500519
Matthew B Jennings, David A Kalmbach, Anthony N Reffi, Christopher B Miller, Timothy Roehrs, Christopher L Drake, Philip Cheng

Objectives: Insomnia disorder is co-morbid with and predictive of developing pain conditions and a key factor in pain interference (PI) - the extent to which pain impedes daily living. Emerging literature suggests treating insomnia with cognitive-behavioral therapy for insomnia reduces co-occurring PI. This secondary data analysis tested the extent to which digital CBT-I (dCBT-I) vs. sleep education reduces and prevents significant PI by treating insomnia.

Methods: Insomnia disorder participants were randomized into dCBT-I (n = 697) and sleep education (n = 623) and reported pre- and post-treatment insomnia and PI. Logistic regressions evaluated intervention effects: 1) reduction of insomnia severity changes in PI and 2) prevention of treatment condition on PI.

Results: The reduction model showed that dCBT-I participants with moderate-to-severe pre-treatment PI experienced 17% odds increase in reduced PI for each one-point reduction in insomnia severity compared to control, OR = 1.17, 95% CI [1.01, 1.35]. In the prevention model, dCBT-I participants with little-to-no pre-treatment PI exhibited a 32% odds reduction of post-treatment progression to moderate-to-severe PI compared to control, OR = 0.68, 95% CI [0.51, 0.90].

Conclusion: dCBT-I demonstrated significant and clinically meaningful reduction and prevention effects against PI in a large sample. dCBT-I may help providers address sleep issues to restore pain-related impairments to daytime function, quality of life, and overall sleep.

目的:失眠与疼痛并存,是疼痛干扰(PI)的一个关键因素,即疼痛对日常生活的影响程度。新出现的文献表明,用认知行为疗法治疗失眠可以减少并发PI。这一次要数据分析测试了数字CBT-I (dCBT-I)与睡眠教育相比,通过治疗失眠减少和预防显著PI的程度。方法:失眠障碍参与者随机分为dCBT-I组(n = 697)和睡眠教育组(n = 623),并报告治疗前和治疗后的失眠和PI。Logistic回归评估干预效果:1)减少失眠严重程度的PI变化,2)预防PI的治疗状况。结果:减少模型显示,与对照组相比,治疗前PI为中重度的dCBT-I参与者失眠严重程度每降低1点,PI降低的几率增加17%,OR = 1.17, 95% CI[1.01, 1.35]。在预防模型中,与对照组相比,治疗前PI很少或没有的dCBT-I参与者治疗后进展为中度至重度PI的几率降低32%,OR = 0.68, 95% CI[0.51, 0.90]。结论:在大样本中,dCBT-I对PI的降低和预防效果显著且具有临床意义。dCBT-I可以帮助提供者解决睡眠问题,以恢复与疼痛相关的白天功能,生活质量和整体睡眠。
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引用次数: 0
Multidimensional Characterization of Long COVID Fatigue. COVID - 19长时间疲劳的多维表征
IF 1.6 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-06-19 DOI: 10.1080/15402002.2025.2522671
Matthew B Maas, Kathryn J Reid, Millenia Jimenez, Melissa Lopez, Janet Miller, Mercedes R Carnethon, Phyllis C Zee, Kristen L Knutson, Igor J Koralnik

Objectives: We performed a multidimensional analysis of mood, cognition, sleep and circadian rhythms in patients with post-acute sequelae of SARS-CoV-2 infection (PASC) with the objective of characterizing the phenotype of PASC fatigue.

Methods: We recruited adult patients from a Neuro-COVID-19 Clinic with persistence of disabling symptoms beyond 6 weeks from acute infection. Self-reported symptoms were assessed with Patient-Reported Outcomes Measurement Information System instruments. We evaluated cognitive performance using NIH Toolbox measures and assessed sleep and rest-activity rhythms by 7 days of wrist actigraphy. We performed level 2 polysomnography in a subset of 20 participants.

Results: We studied 58 participants: 83% White, 59% female and 91% not hospitalized for COVID-19. Fatigue severity was significantly correlated with worse self-reported cognitive abilities but not with objectively measured cognitive performance and with greater depression symptoms, several rest-activity rhythm and light exposure disruption measures, and greater actigraphy measured sleep time and time in bed. A multivariable model found significant, independent associations between fatigue severity and subjective cognitive abilities, depression symptoms, and rest-activity rhythm disruption.

Conclusions: Long total sleep times, disruption of light exposure and circadian rest-activity patterns, depression and subjective cognitive impairment are associated with PASC fatigue. Behaviorally influenced sleep and circadian abnormalities may exacerbate fatigue and be targets for therapeutic interventions.

目的:我们对SARS-CoV-2感染急性后后遗症(PASC)患者的情绪、认知、睡眠和昼夜节律进行了多维分析,目的是表征PASC疲劳的表型。方法:我们从一家神经- covid -19诊所招募了急性感染后持续6周以上致残症状的成年患者。自我报告的症状用患者报告结果测量信息系统工具进行评估。我们使用NIH工具箱测量评估认知表现,并通过7天的手腕活动记录仪评估睡眠和休息-活动节律。我们对20名参与者进行了二级多导睡眠描记术。结果:我们研究了58名参与者:83%白人,59%女性,91%未因COVID-19住院。疲劳严重程度与较差的自我报告认知能力显著相关,但与客观测量的认知表现无关,与更严重的抑郁症状、几种休息-活动节奏和光照干扰测量、更大的活动记录仪测量的睡眠时间和卧床时间相关。一个多变量模型发现,疲劳严重程度与主观认知能力、抑郁症状和休息-活动节律中断之间存在显著的独立关联。结论:总睡眠时间过长、光照和昼夜休息活动模式中断、抑郁和主观认知障碍与PASC疲劳有关。受行为影响的睡眠和昼夜节律异常可能加剧疲劳,成为治疗干预的目标。
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引用次数: 0
A Randomized Pilot Cognitive Behavioral Sleep Health Trial for Young Adults with Type 1 Diabetes. 1型糖尿病青年患者认知行为睡眠健康随机先导试验
IF 1.6 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-06-26 DOI: 10.1080/15402002.2025.2522680
Stephanie Griggs, Quiana Howard, Bethany L Armentrout, Grant A Pignatiello, Kingman P Strohl, Sybil L Crawford, Chiang-Shan R Li, Mary Leuchtag, Ronald L Hickman

Objectives: The purpose of this randomized controlled trial was to determine whether a cognitive-behavioral sleep health self-management intervention (CB-Sleep Health) would be more effective than a time-balanced attention control (AC) condition in improving multiple dimensions of sleep health (self-reported and objectively derived).

Methods: Young adults with T1D (ages 18-26 years) were randomly assigned to a 12-week CB-Sleep Health (n = 21) or AC condition (n = 18). They wore concurrent continuous glucose monitors and actigraphy devices and completed daily sleep surveys for 14 days at baseline, post-intervention, and 3-month follow-up.

Results: Of the randomized participants, 31 (79.5%) completed the post-intervention, while 33 (84.6%) completed the 3-month follow-up. The CB-Sleep Health intervention had a significant effect on alertness and duration compared to the control group. The changes from baseline were -3.21 s vs. +0.71, p = .005 and +18 min vs. -25.8 min, p = .01, respectively. These effects were sustained at the 3-month follow-up.

Conclusions: Longer sleep duration, higher daytime alertness, and sustained sleep efficiency are possible with this CB-Sleep Health intervention in young adults managing a complex condition.

目的:本随机对照试验的目的是确定认知-行为睡眠健康自我管理干预(CB-Sleep health)在改善睡眠健康的多个维度(自我报告和客观得出)方面是否比时间平衡注意控制(AC)条件更有效。方法:青年T1D患者(18-26岁)随机分为12周cb -睡眠健康组(n = 21)和AC组(n = 18)。他们同时佩戴连续血糖监测仪和活动记录仪,并在基线、干预后和3个月随访期间完成了14天的每日睡眠调查。结果:在随机分组的参与者中,31人(79.5%)完成了干预后的治疗,33人(84.6%)完成了3个月的随访。与对照组相比,cb -睡眠健康干预对警觉性和持续时间有显著影响。与基线相比,变化为-3.21 s vs. +0.71, p =。005和+18分钟vs. -25.8分钟,p =。分别为01。这些效果在3个月的随访中持续存在。结论:较长的睡眠时间、较高的白天警觉性和持续的睡眠效率是可能的,这种cb -睡眠健康干预管理复杂的年轻人。
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引用次数: 0
Cognitive Behavioral Therapy for Perinatal Insomnia: Exploring Adherence, Perceived Usefulness of Intervention Components, and their Associations with Sleep Outcomes. 围产期失眠症的认知行为疗法:探索依从性、干预成分的感知有用性及其与睡眠结果的关联。
IF 1.6 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-05-21 DOI: 10.1080/15402002.2025.2501704
Orly Atzmon, Meagan E Crowther, Nina Quin, Laura Cassera, Cornelia Wellecke, Donna M Pinnington, Bei Bei

Objective: To explore the adherence and perceived usefulness of Cognitive Behavioral Therapy for Insomnia (CBT-I) components in the perinatal period and their association with sleep outcomes.

Methods: Seventy-six nulliparous individuals (age M = 33.07 SD ±3.10) from two randomized control trials who received CBT-I at three time points: late pregnancy (35 weeks' gestation), 1.5-3 months postpartum, and 6 months postpartum were analyzed. At each time point, participants self-reported perceived usefulness and adherence for each of the six CBT-I components, and completed the Insomnia Severity Index (ISI), PROMIS Sleep-Related Impairment (PROMIS-SRI), and Dysfunctional Beliefs and Attitudes about Sleep scale (DBAS-16).

Results: All components were perceived as useful by most (74.3-97.1%) participants; adherence varied between components and across time. Cross-sectional multiple regression analyses showed that for "sleep hygiene", higher adherence was associated with lower DBAS-16 at 35 weeks' gestation (small effect). Higher adherence and usefulness to "managing sleep deprivation, sleepiness and fatigue" was associated with lower ISI at 6 months postpartum (small and medium effect size, respectively); higher perceived usefulness was associated with lower PROMIS-SRI at 6 months (small effect; all p-values < .05). There were no significant associations among adherence/usefulness and sleep at 2 months postpartum.

Conclusions: The overall high perceived usefulness of CBT-I components suggests a strong interest in engaging with perinatal sleep health information. Pregnancy may be a crucial time for delivering sleep strategies before facing caregiving duties and heightened postpartum sleep disruptions. These findings provide insights into how CBT-I components are perceived and applied during the perinatal period.

目的:探讨围生期失眠症认知行为疗法(CBT-I)成分的依从性和感知有用性及其与睡眠结局的关系。方法:对两项随机对照试验中76例在妊娠晚期(妊娠35周)、产后1.5 ~ 3个月、产后6个月三个时间点接受CBT-I治疗的未产个体(年龄M = 33.07 SD±3.10)进行分析。在每个时间点,参与者自我报告对每六个CBT-I组成部分的感知有用性和依从性,并完成失眠严重程度指数(ISI)、允诺睡眠相关损害(promise - sri)和睡眠功能失调信念和态度量表(DBAS-16)。结果:大多数(74.3-97.1%)参与者认为所有组件都是有用的;依从性因组件和时间而异。横断面多元回归分析显示,在“睡眠卫生”方面,妊娠35周时,依从性越高,DBAS-16越低(影响小)。较高的依从性和“管理睡眠剥夺、嗜睡和疲劳”的有效性与产后6个月较低的ISI相关(分别为小型和中型效应量);较高的感知有用性与6个月时较低的promise - sri相关(小效应;p值均< 0.05)。产后2个月依从性/有用性与睡眠无显著关联。结论:CBT-I组成部分的总体高感知有用性表明对围产期睡眠健康信息的参与有强烈的兴趣。在面临照顾孩子的责任和产后睡眠中断加剧之前,怀孕可能是制定睡眠策略的关键时期。这些发现提供了如何感知和围产期应用CBT-I组件的见解。
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引用次数: 0
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Behavioral Sleep Medicine
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