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GLP-1R drugs and alcohol use disorder: A definitive therapeutic solution or just another unfulfilled promise? GLP-1R药物与酒精使用障碍:一个明确的治疗方案或只是另一个未实现的承诺?
IF 1.8 4区 医学 Q3 SUBSTANCE ABUSE Pub Date : 2025-09-22 DOI: 10.20882/adicciones.2497
Albert Batalla, Hugo López-Pelayo, Ramón Bataller Albelora
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引用次数: 0
A relational model of wellbeing-centered recovery in alcohol use disorder. 以幸福为中心的酒精使用障碍康复的关系模型
IF 1.8 4区 医学 Q3 SUBSTANCE ABUSE Pub Date : 2025-09-22 DOI: 10.20882/adicciones.2037
Laura Esteban Rodríguez, Ana Sion, Enrique Rubio, Daniel Maldonado Sánchez, Víctor Armada, Gabriel Rubio, Rosa Jurado Barba, In Recovery Group

Wellbeing is a key element among the prevailing definitions of recovery from alcohol use disorder. However, there is an increasing need to develop a unified framework for recovery conceptualization and characterization of its components, as well as the mechanisms to achieve it. The objective of the study was to test a model relating the dimensions involved in recovery. A total of 348 participants with different periods of abstinence (range:1 month-28 years) were assessed using self-reports of psychological well-being, quality of life, negative emotionality and coping strategies. Statistical analyses entailed an exploratory factor analysis (EFA) to uncover the underlying dimensions of psychological measures and a structural equation model (SEM) to elucidate their interrelations. The EFA identified 3 factors that explained 54.95% of the variance: i) Coping; ii) Functional Discomfort (emotional management and recovery capital); iii) Positive Mental Health (well-being and quality of life). The SEM demonstrated robust fit indices (GFI = 1.00, SRMR = .137) and explained 85% of the variance in well-being (R2 = .85). The results suggest that during recovery in AUD, abstinence duration propels coping strategies which can ameliorate negative emotionality and enable an increase in personal and social resources. This process ultimately contributes to heightened well-being and an enhanced quality of life. The study represents a first methodologically sound proposal in Spain for a clinical recovery model centered on well-being. Its comprehensive paradigm not only reshapes our understanding of AUD recovery but also establishes a robust foundation for more efficacious clinical interventions and evaluations.

健康是当前对酒精使用障碍康复的定义中的一个关键因素。但是,越来越需要制定一个统一的框架,以便对恢复的组成部分进行概念化和定性,并制定实现这一目标的机制。本研究的目的是检验一个与康复有关的维度模型。共有348名不同禁欲期(范围:1个月至28年)的参与者接受了心理健康、生活质量、负面情绪和应对策略的自我报告评估。统计分析包括探索性因素分析(EFA)来揭示心理测量的潜在维度和结构方程模型(SEM)来阐明它们之间的相互关系。EFA确定了3个因素,解释了54.95%的差异:1)应对;ii)功能性不适(情绪管理和恢复资本);三)积极的心理健康(幸福和生活质量)。SEM显示了稳健的拟合指数(GFI = 1.00, SRMR = 0.137),并解释了85%的幸福感方差(R2 = 0.85)。结果表明,在AUD恢复期,戒断时间促进了应对策略,可以改善负面情绪,增加个人和社会资源。这个过程最终有助于提高幸福感和提高生活质量。该研究代表了第一个方法学上合理的建议,在西班牙的临床康复模式为中心的福祉。它的综合模式不仅重塑了我们对AUD恢复的理解,而且为更有效的临床干预和评估奠定了坚实的基础。
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引用次数: 0
ALCO-VR Project: A randomized clinical trial evaluating virtual reality cue-exposure Therapy for Treatment-Resistant Alcohol Use Disorder patients. ALCO-VR项目:一项随机临床试验,评估虚拟现实提示暴露治疗难治性酒精使用障碍患者。
IF 1.8 4区 医学 Q3 SUBSTANCE ABUSE Pub Date : 2025-09-22 DOI: 10.20882/adicciones.1958
Alexandra Ghiţă, Olga Hernández-Serrano, Jolanda Fernández-Ruiz, Mariano Gacto-Sánchez, Miquel Monras, Antoni Gual, Bruno Porras-García, Marta Ferrer-García, José Gutiérrez-Maldonado

The management of "treatment-resistant" alcohol use disorder (AUD) often presents significant challenges. Virtual reality (VR) applications, specifically VR cue exposure therapy (VR-CET), offer a potentially complementary approach to the standard treatment (TAU). This randomized clinical trial (RCT) aimed to assess VR-CET's effectiveness when added to TAU, compared to TAU alone, in reducing alcohol craving and anxiety among individuals with treatment-resistant AUD. The study also sought to determine anxiety and craving levels during VR-CET sessions and to explore long-term effects. Eighty-five AUD patients from the Clinic Hospital of Barcelona participated. They were randomly assigned to either an experimental group (EG), receiving VR-CET plus TAU, or a control group (CG), receiving TAU alone. The EG completed six VR-CET sessions alongside TAU, while the CG continued with only TAU. Alcohol craving and anxiety were assessed before and after treatment for both groups, and during VR-CET sessions for the EG. Relapses were monitored at 3-, 6-, and 12-months post-treatment. Results indicated no significant main effects of "type of treatment" (EG vs. CG) on craving or anxiety. However, a significant "time" factor was observed, showing reductions in craving and anxiety from pre-test to post-test, regardless of the treatment type. Within VR-CET sessions, EG participants reported minimal anxiety and craving by the end of the therapy. Importantly, no statistically significant differences in relapse rates were found between the EG and CG at any follow-up period (3, 6, 12 months). The clinical implications of the study, limitations, and research directions are further discussed.

“难治性”酒精使用障碍(AUD)的管理往往面临重大挑战。虚拟现实(VR)应用,特别是VR提示暴露疗法(VR- cet),为标准治疗(TAU)提供了一种潜在的补充方法。这项随机临床试验(RCT)旨在评估在治疗难治性AUD患者中,与单独使用TAU相比,将VR-CET添加到TAU中时,在减少酒精渴望和焦虑方面的有效性。该研究还试图确定VR-CET会话期间的焦虑和渴望水平,并探索长期影响。85名来自巴塞罗那诊所医院的AUD患者参与了研究。他们被随机分配到实验组(EG),接受VR-CET + TAU,或对照组(CG),单独接受TAU。EG组与TAU一起完成了6次VR-CET会话,而CG组只继续使用TAU。在两组治疗前后以及EG的VR-CET期间,对酒精渴望和焦虑进行评估。治疗后3个月、6个月和12个月监测复发情况。结果显示,“治疗类型”(EG vs. CG)对渴望或焦虑没有显著的主要影响。然而,一个重要的“时间”因素被观察到,从测试前到测试后,无论治疗类型如何,渴望和焦虑都有所减少。在VR-CET会话中,EG参与者在治疗结束时报告了最小的焦虑和渴望。重要的是,在任何随访期间(3,6,12个月),EG和CG的复发率均无统计学差异。进一步讨论了本研究的临床意义、局限性和研究方向。
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引用次数: 0
Core vs. peripheral: Exploring social media overvaluation and problematic use in a longitudinal adolescent study. 核心与外围:在一项纵向青少年研究中探索社交媒体的高估和有问题的使用。
IF 1.8 4区 医学 Q3 SUBSTANCE ABUSE Pub Date : 2025-09-22 DOI: 10.20882/adicciones.2237
Víctor Ciudad-Fernández, Alfredo Zarco-Alpuente, Tamara Escrivá-Martínez, Marcos Romero-Suárez, Rosa Baños

Individuals with Overvaluation of the Relative Utility of Social Media (ORUSM) overestimate the value of social media to meet needs, prioritizing it over alternative activities. ORUSM is a key mechanism in the development of Problematic Social Media Use (PSMU), frequently associated with mental health issues. The Plan-net 25 measures ORUSM but lacks evaluation of its longitudinal psychometric properties. PSMU is assessed using six criteria derived from substance use disorders, reclassified into core criteria (mood modification, withdrawal, conflict, relapse) as indicators of problematic use, and peripheral criteria (salience, tolerance) that reflect high engagement without pathology. This study examined the temporal stability and longitudinal invariance of the Plan-net 25, as well as its associations with PSMU criteria and various mental health indicators over six weeks. A sample of 294 adolescents (14-20 years old) completed measures of ORUSM, PSMU, depression, anxiety, loneliness, and life satisfaction. The results showed low to moderate temporal stability of the subscales and longitudinal invariance of the Plan-net 25. ORUSM domains related to emotional regulation, social expression, and boredom management were positively associated with both core and peripheral PSMU criteria. Core criteria predicted worse mental health outcomes, while peripheral criteria were positively associated with life satisfaction. These findings highlight the importance of distinguishing between core and peripheral PSMU criteria.

高估社交媒体相对效用(ORUSM)的个体高估了社交媒体满足需求的价值,优先考虑社交媒体而不是其他活动。ORUSM是问题社交媒体使用(PSMU)发展的关键机制,通常与心理健康问题相关。Plan-net 25测量ORUSM,但缺乏对其纵向心理测量特性的评估。PSMU的评估使用来自物质使用障碍的六个标准,重新分类为核心标准(情绪改变、戒断、冲突、复发),作为有问题使用的指标,以及反映无病理高度参与的外围标准(显著性、耐受性)。本研究在六周内考察了Plan-net 25的时间稳定性和纵向不变性,以及它与PSMU标准和各种心理健康指标的关联。294名14-20岁的青少年完成了ORUSM、PSMU、抑郁、焦虑、孤独和生活满意度的测量。结果表明,Plan-net 25的子尺度具有低至中等的时间稳定性和纵向不变性。与情绪调节、社会表达和无聊管理相关的ORUSM域与核心和外围PSMU标准均呈正相关。核心标准预测较差的心理健康结果,而外围标准与生活满意度呈正相关。这些发现强调了区分核心和外围PSMU标准的重要性。
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引用次数: 0
Social media addiction, personality, psychopathology and gender: Cross-sectional and longitudinal findings in adolescents. 社交媒体成瘾、人格、精神病理和性别:青少年的横断面和纵向研究结果。
IF 1.8 4区 医学 Q3 SUBSTANCE ABUSE Pub Date : 2025-09-22 DOI: 10.20882/adicciones.2084
Francisco Javier López-Fernández, Laura Mezquita, Verónica Vidal-Arenas, Alba Monfil-Carratalá, Generós Ortet, Manuel Ignacio Ibáñez

Social media addiction (SMA) is associated with a wide range of psychological problems in adults, but there are fewer studies about its impact on adolescents. A first step for SMA research in adolescents is to develop instruments to properly examine SMA among them. So the first aim of the current study was to explore the psychometric properties of the Bergen Social Media Addiction Scale (BSMAS) among Spanish adolescents. The study also examined the role of personality in SMA, the associations between SMA and mental health both cross-sectionally and longitudinally, and how these associations may be affected by gender and when personality is considered. A sample of 616 adolescents participated in the study (mean age = 15.01, SD = 1.17, 309 girls), with 1-year follow-up with 222 of them. The BSMAS emerged as a psychometrically sound instrument to assess SMA in adolescents, and showed proper evidence for construct and criterion-related validity, invariance between genders and excellent internal consistency. SMA was related to extraversion, neuroticism and low agreeableness in boys, and to neuroticism, extraversion and lower conscientiousness, openness and agreeableness in girls. SMA showed cross-sectional and longitudinal associations with many psychological problems, with differential associations appearing according to gender, but most disappeared when considering personality. Accordingly, disordered gaming and defiant behaviors predicted SMA after controlling for personality. These findings show the importance of using longitudinal designs and considering personality and gender when examining SMA development and its relations with psychological problems.

社交媒体成瘾(SMA)与成年人的多种心理问题有关,但关于其对青少年影响的研究较少。青少年SMA研究的第一步是开发合适的仪器来检测青少年SMA。因此,本研究的第一个目的是探索卑尔根社交媒体成瘾量表(BSMAS)在西班牙青少年中的心理测量特性。该研究还检查了人格在SMA中的作用,SMA与心理健康之间的横断面和纵向关联,以及这些关联如何受到性别和人格因素的影响。本研究共纳入青少年616人(平均年龄15.01岁,SD = 1.17,女生309人),其中222人随访1年。BSMAS作为一种心理测量学上可靠的工具来评估青少年的SMA,并显示出结构和标准相关的效度,性别之间的不变性和良好的内部一致性。SMA与男孩的外向性、神经质和低宜人性有关,与女孩的神经质、外向性和低严谨性、开放性和宜人性有关。SMA与许多心理问题表现出横断面和纵向的联系,根据性别出现差异的联系,但在考虑人格时大多数消失。因此,在人格控制后,游戏障碍和挑衅行为预测SMA。这些研究结果表明,在研究SMA发展及其与心理问题的关系时,使用纵向设计并考虑个性和性别的重要性。
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引用次数: 0
Drug Dependency Units: what information do they provide for epidemiological surveillance? 药物依赖单位:它们为流行病学监测提供什么信息?
IF 1.8 4区 医学 Q3 SUBSTANCE ABUSE Pub Date : 2025-09-22 DOI: 10.20882/adicciones.2401
Carla Guerra-Tort, Sara Correia, Ana Teijeiro, María Isolina Santiago-Pérez, María Carou, Agustín Montes, Mónica Pérez-Ríos
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引用次数: 0
Association between emotional dependence, traumatic life events, and early maladaptive schemas in women with gambling disorder. 赌博障碍女性情绪依赖、创伤性生活事件与早期适应不良图式的关系。
IF 1.8 4区 医学 Q3 SUBSTANCE ABUSE Pub Date : 2025-09-22 DOI: 10.20882/adicciones.2034
Ana Estévez, Janire Momeñe López, Laura Macía, Paula Jáuregui, Gema Aonso-Diego

Women with gambling disorder (GD) present a high number of traumatic life events, early maladaptive schemas, and emotional dependence towards the partner. The objectives of the study focused on (I) analyzing the relationships between traumatic life events, schemas, and emotional dependence in women with GD; (II) analyzing the differences in traumatic life events, emotional dependence, and schemas between women and men with GD; (III) analyzing the predictive role of traumatic life events and schemas in emotional dependence in women with GD; and (IV) analyzing the mediating role of schemas between traumatic life events and emotional dependence in a clinical sample of women with GD. The sample comprised 60 women (M = 49.07, SD = 12.70) and 48 men (M = 41.33, SD = 12.32) who were in outpatient treatment for GD. The findings reflected a significantly positive relationship between traumatic life events and early maladaptive schemas and emotional dependence (r between .31 and .57). Women reported higher scores in traumatic life events and the early maladaptive schema of self-sacrifice, whereas men did so in emotional dependence (attention-seeking) and in the early maladaptive schema of social isolation (d ≥ .34). Finally, the mediating role of enmeshment and abandonment schemas in the relationship between traumatic life events and separation anxiety was demonstrated. The results allow the development of better interventions for women with GD. It is crucial to address enmeshment and abandonment patterns in women with GD with a history of traumatic life events to prevent them from leading to high emotional dependence on the partner.

女性赌博障碍(GD)表现出大量的创伤性生活事件,早期适应不良图式和对伴侣的情感依赖。本研究的目的主要集中在:(1)分析焦虑女性创伤性生活事件、图式和情绪依赖之间的关系;(二)分析性别焦虑患者在创伤性生活事件、情感依赖、心理图式等方面的差异;(三)分析创伤性生活事件和图式对焦虑女性情绪依赖的预测作用;(四)分析心理图式在焦虑女性创伤性生活事件与情绪依赖之间的中介作用。样本包括60名女性(M = 49.07, SD = 12.70)和48名男性(M = 41.33, SD = 12.32),均在门诊接受GD治疗。研究结果反映了创伤性生活事件与早期适应不良图式和情感依赖之间的显著正相关。31和0.57)。女性在创伤性生活事件和自我牺牲的早期适应不良图式中得分较高,而男性在情感依赖(寻求注意)和社会孤立的早期适应不良图式中得分较高(d≥0.34)。最后,探讨了依恋和抛弃图式在创伤性生活事件与分离焦虑关系中的中介作用。研究结果有助于为患有性别焦虑的女性制定更好的干预措施。对于有创伤性生活事件历史的焦虑女性来说,解决纠缠和抛弃模式是至关重要的,以防止它们导致对伴侣的高度情感依赖。
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引用次数: 0
An integrated behavioral approach to understanding sociocognitive determinants and risk profiles of cannabis use in adolescents. 综合行为方法理解社会认知决定因素和青少年使用大麻的风险概况。
IF 2.2 4区 医学 Q3 SUBSTANCE ABUSE Pub Date : 2025-05-30 DOI: 10.20882/adicciones.1961
María-Carmen Torrejón-Guirado, Shahab Jolani, Marta Lima-Serrano, Liesbeth Mercken, Hein De Vries

Cannabis experimentation usually begins during adolescence, and it is associated with the development of mental disorders, and regular use in adulthood. This study aims to analyze the determinants and the trajectories of cannabis use in adolescence. A longitudinal study was conducted with 1,051 adolescents aged 14-18 years who completed a baseline and 6-month follow-up survey based on the I-Change Model. Two cross-sectional and one longitudinal regression analyses were performed to identify which determinants are associated with cannabis use. Then, the five cannabis use trajectories that were found were compared using ANOVA with Tukey's post hoc comparisons. The results showed that at 6 months of follow-up, 669 adolescents had remained non-users, while 187 non-users became users, of whom 121 were experimental and 66 regular users. Data analysis revealed the influence on cannabis use of having boyfriend/girlfriend, sensation seeking, not being convinced about the disadvantages of cannabis use, having peer influence favoring cannabis use and a positive intention to use cannabis in the future. At the beginning, non-users differed on perceptions about the sociocognitive factors from consistent users, but not of the new users. When comparing sociocognitive factors at follow-up, the scenario change, and they are the new users who showed more sociocognitive perceptions favoring cannabis than non-users. Considering the determinants of cannabis use from an integrated behavioral approach can be useful to develop prevention campaigns for this substance. This should provide healthy alternatives to the search for sensations, reinforce a negative attitude towards cannabis use, and influence peer influence and self-efficacy in risky situations/emotions that invite its consumption.

大麻实验通常在青春期开始,它与精神障碍的发展和成年期的经常使用有关。本研究旨在分析青少年大麻使用的决定因素和轨迹。对1051名14-18岁的青少年进行了一项纵向研究,他们完成了基于I-Change模型的基线和6个月的随访调查。进行了两次横断面和一次纵向回归分析,以确定哪些决定因素与大麻使用有关。然后,将发现的五种大麻使用轨迹与Tukey的事后比较使用方差分析进行比较。结果显示,在6个月的随访中,669名青少年仍然不使用手机,而187名不使用手机的青少年成为了手机用户,其中121名是实验性用户,66名是常规用户。数据分析显示,有男朋友/女朋友、寻求刺激、不相信使用大麻的缺点、有有利于使用大麻的同伴影响以及将来使用大麻的积极意图对大麻的使用产生了影响。一开始,非用户对社会认知因素的看法与老用户不同,但与新用户不同。当比较随访时的社会认知因素时,情况发生了变化,新使用者比非使用者表现出更多的社会认知感知。从综合行为方法考虑大麻使用的决定因素可能有助于开展针对这种物质的预防运动。这应该为寻找感觉提供健康的替代办法,加强对使用大麻的消极态度,并在导致吸食大麻的危险情况/情绪中影响同伴的影响和自我效能。
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引用次数: 0
Psychometric properties of the Cuestionario de Evaluación de las Relaciones Familiares Básicas (CERFB) in substance use disorder: Marital and parental relationships. 基本家庭关系评估问卷(CERFB)在物质使用障碍中的心理测量特性:婚姻和父母关系。
IF 2.2 4区 医学 Q3 SUBSTANCE ABUSE Pub Date : 2025-05-30 DOI: 10.20882/adicciones.1821
Laura Mercadal Salort, Meritxell Campreciós Orriols, Antonino Callea, Maurizio Coletti, Anna Vilaregut Puigdesens

Family therapy stands out among the main psychotherapeutic treatments for substance use disorder. Nonetheless, we should point out a deficit of psychometric instruments for family evaluation, specifically validated for this disorder in Spanish population. It is necessary to have questionnaires available to evaluate family dynamics, commencing with the quantification of the marital relationship and the parenting exercise which result in design-suitable interventions. The present study aims to validate and determine the clinical applicability of the Cuestionario de Evaluación de las Relaciones Familiares Básicas (CERFB; in English, Basic Family Relations Assessment Questionnaire) in substance use disorder. One hundred and fifty-two couples of Spanish nationality (N = 304 participants) with a child suffering from substance use disorder completed the CERFB as well as other means of family evaluation. The results of the CFA presented the validity of the two-factor structure model of the CERFB of the original version within the general Spanish population. The results of the invariance factor across sex allowed us to assume the configural invariance between the groups. However, the metric invariance based on the sex could not be assumed. The validity evidence based on relations to other variables determined significant correlations between the CERFB and the Dyadic Adjustment Scale and the Parental Bonding Instrument. The reliability of both scales was satisfactory: Marital (α = .93; ω = .93) and Parental (α = .82; ω = .81) Normative data are provided. The CERFB is the first instrument to come about which is validated within the clinical Spanish population and which evaluates the family within substance use disorder.

家庭治疗在物质使用障碍的主要心理治疗中脱颖而出。尽管如此,我们应该指出家庭评估的心理测量工具的缺陷,特别是在西班牙人群中验证了这种疾病。有必要提供调查问卷来评估家庭动态,从量化婚姻关系和养育子女开始,从而产生适合设计的干预措施。本研究旨在验证和确定Evaluación亲属亲属关系问卷Básicas (CERFB;基本家庭关系评估问卷)。152对西班牙国籍夫妇(N = 304名参与者)的孩子患有物质使用障碍,他们完成了CERFB以及其他家庭评估方法。CFA的结果证明了原始版本CERFB的双因素结构模型在西班牙普通人群中的有效性。跨性别不变性因子的结果使我们能够假设群体之间的结构不变性。然而,不能假设基于性别的度规不变性。基于与其他变量关系的效度证据表明,CERFB与二元调整量表和亲代依恋量表之间存在显著的相关性。两个量表的信度均令人满意:婚姻(α = 0.93;ω = 0.93)和parent (α = 0.82;ω = .81)提供了规范性数据。CERFB是第一个在西班牙临床人群中得到验证的工具它评估了药物使用障碍中的家庭。
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引用次数: 0
School prevention programs for problematic Internet use, problematic gambling and video game addiction in Spain: A systematic review. 西班牙学校预防网络使用问题、赌博问题和电子游戏成瘾的项目:系统回顾。
IF 2.2 4区 医学 Q3 SUBSTANCE ABUSE Pub Date : 2025-05-30 DOI: 10.20882/adicciones.2045
Víctor J Villanueva-Blasco, Dalila Eslava, Eduardo Ibor Bernalte, Manuel Isorna Folgar, Antonio Rial-Boubeta

The present work aims to identify the school prevention programs for problematic Internet use, problematic gambling and video game addiction existing in Spain, reporting on their characteristics and effectiveness, establishing different degrees of recommendation. A systematic review was carried out with two complementary strategies: a) a search in the Xchange, Good Practices in Addictions (PPBB), Evidence-Based Prevention and EDDRA portals; b) a search of Web of Science, PudMed/MEDLINE, APA PsycInfo, Scopus or Cochrane Library. The search included the keywords "Spain", "gambling", "videogames", "Internet", "social network", "school prevention" and synonyms. Six programs were identified, of which five had empirical studies to evaluate their effectiveness. All were based on theoretical models related to the etiology of the problem, used an active and interactive methodology and were implemented by professionals with specific training. The programs ¿Qué te juegas?, Ludens and Safety.net achieved a higher degree of recommendation. For the Cubilete and PrevTec 3.1 programs, additional studies of its effectiveness are suggested. Regarding good practice portals, it is suggested that evidence be prioritized over accessibility and that the specific problem for which each program has been proven effective be clearly indicated. Based on these findings, we insist on the need to provide empirical evidence regarding any prevention strategy or program. Finally, some questions of interest are raised, such as the convenience of considering the prevention of these new problems jointly or separately.

目前的工作旨在确定西班牙存在的问题网络使用,问题赌博和视频游戏成瘾的学校预防方案,报告其特点和有效性,建立不同程度的推荐。采用两种互补策略进行了系统评价:A)在交换、成瘾良好做法(PPBB)、循证预防和EDDRA门户网站中进行搜索;b)搜索Web of Science, PudMed/MEDLINE, APA PsycInfo, Scopus或Cochrane Library。搜索的关键词包括“西班牙”、“赌博”、“电子游戏”、“互联网”、“社交网络”、“学校预防”和同义词。确定了六个项目,其中五个项目进行了实证研究以评估其有效性。所有这些都是基于与问题病因相关的理论模型,采用积极和互动的方法,并由经过专门培训的专业人员实施。这些节目“ququest juegas”?, Ludens和safy.net获得了更高的推荐程度。对于Cubilete和PrevTec 3.1程序,建议对其有效性进行进一步研究。关于良好实践门户,建议将证据优先于可访问性,并明确指出每个程序已被证明有效的具体问题。基于这些发现,我们坚持需要提供有关任何预防策略或计划的经验证据。最后,提出了一些值得关注的问题,如联合或单独考虑这些新问题的预防是否方便。
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