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Can Acellular Dermal Matrix and Kombucha Cellulose Membrane Be Used in Calvarial Reconstruction? 无细胞真皮基质和康普茶纤维素膜能用于颅骨重建吗?
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-08-10 DOI: 10.4274/jarem.galenos.2023.30306
Osman Boyalı, Ömer Özdemir, Furkan Diren, A. Bilir
Can Acellular Dermal Matrix and Kombucha Cellulose Membrane Be Used in Calvarial
无细胞真皮基质和康普茶纤维素膜能用于Calvaria吗
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引用次数: 0
Evaluation of Factors Affecting Morbidity in Patients with Osteogenesis Imperfecta 影响成骨不全患者发病率的因素评价
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-28 DOI: 10.4274/jarem.galenos.2023.62534
Parisa Hosseini, Nur Canbolat, E. Gürdeniz, C. Chousein, H. Balci, F. Bilgili, I. Edipoglu, Mehmet I. Buget
11,07±7,70
11,07 ± 7,70
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引用次数: 0
The Effects of the COVID-19 Pandemic on Patients with Trauma Presented to the Emergency Department: A Multicentre Experience in İstanbul COVID-19大流行对急诊创伤患者的影响:İstanbul的多中心经验
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-28 DOI: 10.4274/jarem.galenos.2023.79664
M. Çalık, Dilay Satılmış, Burcu Genç Yavuz, R. Güven, Ş. Çolak, Özgür Söğüt, I. Altundag, E. Altınbilek, I. Tayfur, Nihat Müjdat Hökenek, Gökhan Eyüpoğlu, T. Akdemir
Objective: This study examines the characteristics of patients with trauma who presented to the emergency department before and after the novel coronavirus disease-2019 (COVID-19) pandemic and analyze the effects on the traumatic injuries. Methods: In this study, medical records of patients who presented to the emergency departments of seven hospitals operating as tertiary level hospitals in İstanbul between March-June 2018, March-June 2019, and March-June 2020 are due to trauma were retrospectively analyzed. The clinical and demographic characteristics of traumatic injuries before and after the pandemic were compared. Results: In our study, 4088 trauma patients’ data were reviewed: 1279 in March-June 2018, 1684 in March-June 2019, and 1125 in March-June 2020. When the total number of patients was examined, it was noticed that the number of patients decreased significantly during the COVID-19 pandemic. No significant difference was found between the periods regarding the sex and trauma mechanisms of the patients. The mean age was higher in patients admitted in 2020 compared to previous years. In our study, incidences of intracranial hemorrhage, femur fracture, lung injuries, and mortality rates were higher in March-June 2020 compared to previous years. Conclusion: In March-June 2020, compared to the previous year, there was a 34% decrease in trauma cases admitted to the emergency department. Albeit no difference was found between the periods regarding trauma mechanisms, the higher mortality in the March-June 2020 period indicates that trauma continues to be one of the major causes of death despite the pandemic.
目的:研究新型冠状病毒病2019(新冠肺炎)大流行前后急诊科就诊的创伤患者的特点,并分析其对创伤的影响。方法:在本研究中,回顾性分析了2018年3月至6月、2019年3月~6月至2020年3月期间因创伤就诊于伊斯坦布尔七家三级医院急诊科的患者的病历。比较了疫情前后创伤的临床和人口学特征。结果:在我们的研究中,审查了4088名创伤患者的数据:2018年3-6月1279人,2019年3-6月1684人,2020年3-6月1125人。当检查患者总数时,人们注意到,在新冠肺炎大流行期间,患者人数显著减少。在患者的性别和创伤机制方面,两个时期之间没有发现显著差异。与前几年相比,2020年入院患者的平均年龄更高。在我们的研究中,与前几年相比,2020年3-6月的颅内出血、股骨骨折、肺部损伤和死亡率更高。结论:与前一年相比,2020年3月至6月,急诊科收治的创伤病例减少了34%。尽管在创伤机制方面没有发现不同时期的差异,但2020年3月至6月期间的较高死亡率表明,尽管疫情肆虐,创伤仍然是死亡的主要原因之一。
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引用次数: 0
Investigation of the Effect of Low-positive HER-2 on Neoadjuvant Chemotherapy Response in Hormone-positive Breast Cancer Patients 低阳性HER-2对激素阳性乳腺癌症患者新辅助化疗反应影响的研究
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-28 DOI: 10.4274/jarem.galenos.2023.30074
Kubilay Karaboyun, M. Öznur, A. Yolcu, Yakup Iriagac, Selcuk E. Seber
Objective: Recently, it has been suggested that low-positive human epidermal growth factor receptor-2 (HER-2) is a separate group of breast cancer. We examined the effect of low-positive HER-2 on neoadjuvant chemotherapy (NACT). Methods: This retrospective study included female patients aged >18 years who were diagnosed with histologically proven breast cancer between January 1, 2016, and January 1, 2020, and had breast surgery after NACT. Patients with triple-negative, estrogen receptor (<10%) weak positive, HER-2 immunohistochemical (IHC) scores 3+ or 2+/FISH-positive patients, and metastatic patients were excluded. Pathological complete response (pCR) was defined as the no invasive and in situ residue in the breast and lymph nodes in surgery after NACT. Results: One hundred twenty seven patients were included in this study. HER-2 IHC-score “0” patients were 55 (43.3%), “1+” patients were 52 (40.9%), and “2+” patients were 20 (15.7%). Nine (7.1%) patients showed a complete response to NACT. In the univariate analysis with clinicopathological variables of the patients to predict the complete response to NACT; estrogen receptor [odds ratio (OR): 0.97, 95% confidence interval (CI): 0.96-0.99, p=0.012], Ki-67 (OR: 1.12, 95% CI: 1.06-1.18, p<0.001), tumor grade (OR: 0.036, 95% CI: 1.13-30.36, p=0.036), and lymphovascular invasion (OR: 0.11, 95% CI: 0.01-0.93, p=0.043) showed the predictive features. In the multivariate analysis, Ki-67 (OR: 1.10, 95% CI: 0.04-1.17, p=0.001) was found to be an independent predictor of pCR. Conclusion: We determined that the low-positive-HER2 group has no effect on the treatment response in patients treated with NACT. We found that Ki-67 was an independent predictive for pCR.
目的:近年来有研究表明,低阳性人表皮生长因子受体-2(HER-2)是癌症的一个独立组。我们研究了低阳性HER-2对新辅助化疗(NACT)的影响。方法:这项回顾性研究包括年龄>18岁的女性患者,她们在2016年1月1日至2020年1月之间被诊断为组织学证实的癌症,并在NACT后进行了乳腺手术。排除三阴性、雌激素受体(<10%)弱阳性、HER-2免疫组织化学(IHC)评分为3+或2+/FISH阳性的患者和转移性患者。病理完全反应(pCR)被定义为NACT后手术中乳房和淋巴结中无侵袭性和原位残留。结果:127名患者被纳入本研究。HER-2 IHC评分为“0”的患者有55名(43.3%),“1+”的患者52名(40.9%),“2+”的患者20名(15.7%)。9名(7.1%)患者对NACT有完全反应。在对患者的临床病理变量进行单变量分析以预测对NACT的完全反应;雌激素受体[比值比(OR):0.97,95%置信区间(CI):0.96-0.99,p=0.012],Ki-67(OR:1.12,95%CI:1.06-1.18,p<0.001),肿瘤分级(OR:0.036,95%CI:1.13-3.36,p=0.036)和淋巴血管侵袭(OR:0.11,95%CI:0.0.01-0.93,p=0.043)显示了预测特征。在多变量分析中,Ki-67(OR:1.10,95%CI:0.04-1.17,p=0.001)被发现是pCR的独立预测因子。结论:我们确定低阳性HER2组对NACT患者的治疗反应没有影响。我们发现Ki-67是pCR的独立预测因子。
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引用次数: 0
Cryopreservation of Deciduous Teeth Originated Mesenchymal Stem Cells with Different Techniques 不同技术对乳牙间充质干细胞的冷冻保存
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-28 DOI: 10.4274/jarem.galenos.2023.63497
T. Akkoç, D. Genç, T. Akkoç
: Akkoç T, Genç D, Akkoç T. Cryopreservation of Deciduous Teeth Originated Mesenchymal Stem Cells with Different Techniques
: Akkoç T, Genç D, Akkoç T.乳牙间充质干细胞低温保存的研究
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引用次数: 0
Evaluation of School-age Hearing Screening Applications: The Tele-audiological Perspective 学龄期听力筛查应用的评价:远程听力学视角
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-28 DOI: 10.4274/jarem.galenos.2022.99608
A. Ceylan, E. Kara, M. Kesimli, Deniz Kaya, A. Ataş
Objective: Hearing health is one of the areas that should be considered especially in childhood. School-age hearing screening (SAHS) is important for the detection and prevention of hearing loss. The aim of our study is to compare the use of teleaudiological applications for SAHS with standard SAHS applications and to determine possible similarities or differences between the methods. Methods: The study was carried out with a total of 224 students who were first-year students in the same primary school within the borders of Istanbul. The study was completed in two phases with a test session at 15-day intervals. In the first stage, video-otoscope images of all individuals who would be subjected to standard SAHS were recorded and tympanometry test was performed. In the second stage, SAHS results were recorded with the tele-audiological method. Results: According to the tympanometry results obtained from the participants, it was determined that the rate of abnormal hearing was 4.5%. According to the video-otoscope results, which were evaluated as asynchronous, the number of students suspected of dense earwax plug and membrane pathology was 6.7% in the left ear and 5.8 in the right ear. According to the SAHS method results, the average rate of passing and failing the test in the standard method was 12.9% in the right ear, and 12.9% in the left ear. According to the results of the tele-audiological method of the same student group, the rate of failing the test was 16.1% in the right ear and 15.2 in the left ear. Conclusion: Measuring tele-audiologically or using the standard method did not affect the test results. Accordingly, the test result is independent of whether the test is performed with the tele-audiological or standard method.
目的:听力健康是儿童尤其是青少年应重视的问题之一。学龄听力筛查(SAHS)对于发现和预防听力损失非常重要。本研究的目的是比较远程听力学在SAHS中的应用与标准SAHS的应用,并确定两种方法之间可能的相似或差异。方法:研究对象为伊斯坦布尔境内同一所小学的224名一年级学生。研究分两个阶段完成,每隔15天进行一次测试。在第一阶段,记录所有将接受标准SAHS的个体的视频耳镜图像,并进行鼓室测量测试。第二阶段,用远程听力学方法记录SAHS结果。结果:根据参与者的鼓室测量结果,确定听力异常率为4.5%。视频耳镜检查结果为非同步检查,疑似左耳致密耳垢塞及膜状病变的学生占6.7%,右耳占5.8。根据SAHS方法结果,标准方法的平均合格率为右耳12.9%,左耳12.9%。同一学生组远程听力学测试结果显示,右耳不合格率为16.1%,左耳不合格率为15.2%。结论:远程听力学测量或使用标准方法不影响测试结果。因此,测试结果与测试是否使用远程听力学方法或标准方法无关。
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引用次数: 0
Determination of Physical Activity Level, Functional Capacity and Depression in Children with Digital Game Addiction 数字游戏成瘾儿童体力活动水平、功能能力与抑郁的测定
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-28 DOI: 10.4274/jarem.galenos.2023.28942
Y. Karaaslan, Fatih Özyurt, Umut Karaaslan
Objective: The aim of this study was to determine the physical activity level, functional capacity, and depression in children with digital game addiction (DGA). Methods: Ninety-nine children (mean age: 10±1.53 years) with DGA were included in the study. Demographic, physical, and clinical characteristics were recorded. DGA was evaluated using the Digital Game Addiction Scale for Children, physical activity level with the Primary School Students’ Physical Activity Questionnaire, functional capacity with the 2-Minute Walk test, and depression with the Depression Scale for Children. Results: Of the children, 17.2% were in the low-risk group, 41.4% were in the risky group, 26.3% were in the dependent group, and 15.2% were in the highly dependent group. DGA had a high negative correlation with physical activity level (r=-0.659; p=0.001), a weak positive correlation with depression (r=0.342; p=0.001), but no correlation with functional capacity (p>0.05). Simultaneously, it was found that physical activity and depression were found to be independent factors of the DGA with 43.4% of the variance. Additionally, a significant difference was found in terms of physical activity level and depression in children with DGA at different levels (p<0.05). Conclusion: In this study, a negative relationship was found between DGA and physical activity level, and a positive relationship with depression. It is important to raise the awareness of children and families about DGA. Additionally, children can be directed to various exercise programs to increase physical activity levels and reduce depression associated with DGA.
目的:本研究旨在确定数字游戏成瘾(DGA)儿童的体力活动水平、功能能力和抑郁。方法:将99名DGA患儿(平均年龄:10±1.53岁)纳入研究。记录人口统计学、生理学和临床特征。DGA采用儿童数字游戏成瘾量表、小学生体育活动量表、2分钟步行测试功能能力和儿童抑郁量表进行评估。结果:在这些儿童中,17.2%属于低危组,41.4%属于高危组,26.3%属于依赖组,15.2%属于高度依赖组。DGA与体力活动水平呈高度负相关(r=-0.659;p=0.001),与抑郁呈弱正相关(r=0.342;p=0.001。结论:DGA与儿童体力活动水平呈负相关,与抑郁呈正相关。提高儿童和家庭对DGA的认识很重要。此外,可以指导儿童进行各种锻炼计划,以提高身体活动水平,减少与DGA相关的抑郁。
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引用次数: 0
Analysis of Body Composition and Dynamic and Static Balance in Individuals Previously Infected with COVID-19 新冠肺炎既往感染者身体成分及动静态平衡分析
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-28 DOI: 10.4274/jarem.galenos.2023.69772
F. Bodur, D. Şenol, Demet Şencan, Cenk Murat Özer
Objective: This study examines body composition and the parameters of dynamic and statistic balance in individuals previously infected with coronavirus disease-2019 (COVID-19) and to compare these individuals with the control group. Methods: A total of 112 volunteering individuals, 56 individuals previously diagnosed with COVID-19 via polymerase chain reaction test (COVID-19 group), and 56 healthy individuals (control group), between the ages of 18 and 26 participated in the study. Sociodemographic characteristics of the individuals in both groups and their COVID-19 related information were recorded. While Tanita BC 418 (Tokyo, Japan, 2015) operating with bioelectrical impedance was used for body composition measurement, the flamingo balance test and Y balance test were used respectively for static and dynamic balance measurements. Results: Because of the statistical analysis conducted, it was found that the COVID-19 group had a statistically significant lower balance level than the control group according to the Y balance test anterior, posterolateral, posteromedial, total reach values and flamingo balance test values in terms of balance performance (p<0.05). Conclusion: Because of the study, no significant difference was found in the body composition of individuals aged 18-26 previously infected with COVID-19 compared with healthy individuals of the same age. In terms of static and dynamic balance parameters, it was found that those who were previously infected with COVID-19 were more negatively affected than the control group. We think that determining these balance disorders seen after the COVID-19 infection will be a guide in planning rehabilitation programs for actual needs.
目的:本研究检查了先前感染2019冠状病毒病(新冠肺炎)的个体的身体成分以及动态和统计平衡参数,并将这些个体与对照组进行比较。方法:共有112名志愿者、56名经聚合酶链式反应检测确诊为新冠肺炎的患者(新冠肺炎组)和56名18至26岁的健康患者(对照组)参与研究。记录了两组个体的社会形态特征及其新冠肺炎相关信息。Tanita BC 418(日本东京,2015)使用生物电阻抗进行身体成分测量,火烈鸟平衡测试和Y平衡测试分别用于静态和动态平衡测量。结果:由于进行了统计分析,根据Y平衡测试前、后外侧、后内侧、总到达值和火烈鸟平衡测试值,新冠肺炎组的平衡水平低于对照组(p<0.05),先前感染新冠肺炎的18-26岁个体的身体成分与相同年龄的健康个体相比没有发现显著差异。在静态和动态平衡参数方面,研究发现,先前感染新冠肺炎的人比对照组受到的负面影响更大。我们认为,确定新冠肺炎感染后出现的这些平衡障碍将是根据实际需求规划康复计划的指南。
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引用次数: 1
Pathogenetic and Prognostic Importance of Cyclin D1, Estrogen Receptor, and TAG72 in Cutaneous Vascular Tumors and Pericytic Tumors 细胞周期蛋白D1、雌激素受体和TAG72在皮肤血管肿瘤和周细胞肿瘤中的发病机制和预后意义
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-26 DOI: 10.4274/jarem.galenos.2022.35220
S. Karabağ, K. Erdoğan, Akif Mirioğlu, Ö. Zorlu, G. Gönlüşen, S. Özbarlas
{"title":"Pathogenetic and Prognostic Importance of Cyclin D1, Estrogen Receptor, and TAG72 in Cutaneous Vascular Tumors and Pericytic Tumors","authors":"S. Karabağ, K. Erdoğan, Akif Mirioğlu, Ö. Zorlu, G. Gönlüşen, S. Özbarlas","doi":"10.4274/jarem.galenos.2022.35220","DOIUrl":"https://doi.org/10.4274/jarem.galenos.2022.35220","url":null,"abstract":"","PeriodicalId":56162,"journal":{"name":"Journal of Academic Research in Medicine-JAREM","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48655031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship Between Early Diffusion Weighted Imagining Lesion Patterns and Stroke Mechanisms at Atherosclerotic Diseases of Medial Cerebral Artery 大脑内动脉粥样硬化性疾病早期弥散加权成像病变模式与脑卒中机制的关系
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-12-26 DOI: 10.4274/jarem.galenos.2022.32032
Kursat Usalan, Sibel Üstün Özek, Şahinde Fazilet Hız
{"title":"The Relationship Between Early Diffusion Weighted Imagining Lesion Patterns and Stroke Mechanisms at Atherosclerotic Diseases of Medial Cerebral Artery","authors":"Kursat Usalan, Sibel Üstün Özek, Şahinde Fazilet Hız","doi":"10.4274/jarem.galenos.2022.32032","DOIUrl":"https://doi.org/10.4274/jarem.galenos.2022.32032","url":null,"abstract":"","PeriodicalId":56162,"journal":{"name":"Journal of Academic Research in Medicine-JAREM","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46794115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Academic Research in Medicine-JAREM
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